Orly Alter - Biographical Sketch
Orly Alter - LinkedIn Profile







Institution Degree Year Field
Stanford University, CA Postdoctoral Fellowship 2004 Genetics
Stanford University, CA  Ph.D.1 1999  Applied Physics 
Tel Aviv University, Israel B.Sc. magna cum laude 1989 Physics




2024–

Chief Scientific Officer (CSO) and Co-Founder,
Prism AI Therapeutics, Inc.
2016–


Investigator, and
Member of the Cancer Control and Population Sciences Program,
Huntsman Cancer Institute (HCI), University of Utah
2011–

Adjunct Associate Professor, Department of Human Genetics,
University of Utah
2010–



Utah Science, Technology, and Research (USTAR)
Associate Professor, Department of Bioengineering and
Scientific Computing and Imaging (SCI) Institute,
University of Utah
2010–2016

Adjunct Associate Professor, Department of Mathematics,
University of Texas at Austin
2004–2010


Assistant Professor, Department of Biomedical Engineering, and
Fellow, Institute for Cellular and Molecular Biology,
University of Texas at Austin
1998–2004 Postdoctoral Fellow, Department of Genetics, Stanford University
1991–1998

Graduate Research Assistant, Department of Applied Physics,
Stanford University




2025




25th Advances in Genome Biology and Technology (AGBT) General Meeting (Marco Island, FL), Plenary Lecture, "Multi-Tensor AI/ML Uniquely Able to Identify Actionable and Mechanistically Interpretable Predictors from Small-Cohort and Noisy High-Dimensional Multi-Omic Clinical Data"
2020


Amazon Web Services (AWS) Education Research Webinar, "Multi-Tensor Decompositions for Personalized Cancer Diagnostics, Prognostics, and Therapeutics"
2018


  
14th International Conference on Latent Variable Analysis and Signal Separation (LVA ICA 2018) (Guildford, United Kingdom), Plenary Lecture, "Comparative Spectral Decompositions for Personalized Cancer Diagnostics and Prognostics"2
2018



2018 Society for Industrial and Applied Mathematics (SIAM) Conference on Applied Linear Algebra (SIAM-ALA18) (Hong Kong, China), Plenary Lecture, "Comparative Spectral Decompositions for Personalized Cancer Diagnostics and Prognostics"
2015–2023


  
NIH/National Cancer Institute (NCI) Physical Sciences in Oncology Network (PS-ON), U01 Project Grant, "Multi-Tensor Decompositions for Personalized Cancer Diagnostics and Prognostics"3,4,5
2014




American Association of Physicists in Medicine (AAPM) Science Council Session Winner (SCSW) Lecture Award, "Singular Value Decomposition Identifies Transcript Length Distribution Functions from DNA Microarray Data and Reveals Evolutionary Forces Globally Affecting Glioblastoma Multiforme Metabolism"6
2014


  
Bloomberg L.P. Distinguished Speaker Lectures, "Discovery of Principles of Nature from Matrix and Tensor Modeling of Large-Scale (Molecular Biological) Data," and "(Physics-Inspired) Mathematical Vocabulary for Discovery from Data"7
2009–2015


  
NSF/Division of Mathematical Sciences (DMS), Faculty Early Career Development (CAREER) Award, "Integrative and Comparative Tensor Algebra Models of DNA Microarray Data from Different Studies of the Cell Cycle"8,9
2007–2015


  
NIH/National Human Genome Research Institute (NHGRI), R01 Project Grant, "Tensor Computations for Modeling Large-Scale Molecular Biological Data – from Discovery of Patterns to Discovery of Principles of Nature"10,11
2006



6th International Conference on Independent Component Analysis and Blind Source Separation (ICA 2006) (Charleston, SC), Plenary Lecture, "Uncovering the Molecular Biological Principles That Govern Cellular Systems with Blind Source Separation Models"
2005

  
International Linear Algebra Society (ILAS) Linear Algebra and Its Applications (LAA) Lecture, "Genomic Signal Processing: From Matrix Algebra to Genetic Networks"12
2000–2005

  
NIH/NHGRI, K01 Individual Mentored Research Scientist Development Award in Genomic Research and Analysis, "Mathematical Tools for Gene Expression Data Analysis"13,14
1999–2003

  
DOE/Alfred P. Sloan Foundation, Postdoctoral Fellowship in Computational Molecular Biology, "Analytical and Computational Tools for Genome-Wide Gene Expression Data Analysis"15
1998



  
American Physical Society (APS), Outstanding Doctoral Thesis Research in Atomic, Molecular, or Optical Physics (DAMOP) Award Finalist, "Impossibility of Determining the Quantum Wavefunction of a Single System and Fundamental Limit to External Force Detection"16
1997




5th International Conference on Squeezed States and Uncertainty Relations (FICSSUR 1997) (Balatonfüred, Hungary), Plenary Lecture, "Impossibility of Determining the Quantum Wavefunction of a Single System and Fundamental Limit to External Force Detection"




Mostly since 2015

  3/2025


Society for Industrial and Applied Mathematics (SIAM) Conference on Computational Science and Engineering (CSE25) (Fort Worth, TX), Organizing Committee Member
  1/2025–

International Linear Algebra Society (ILAS), Joint Mathematics Meetings (JMM) Speaker Selection Committee Member
  2/2024–

University of Utah, Scientific Computing and Imaging (SCI) Institute, Associate Director
  2/2023–



NIH/National Cancer Institute (NCI) -DOE Cancer Moonshot Collaboration, Scientific Advisory Board Member, "Innovative Methodologies and New Data for Predictive Oncology Model Evaluation (IMPROVE) Project"
11/2024, 11/2023, 11/2022, 11/2020
Supercomputing (SC) NCI Computational Approaches for Cancer Workshop (CAFCW) (Atlanta, GA;17 Denver, CO;18 Dallas, TX;19 Virtual), Workshop Organizing Committee Member
  1–12/2023, 1–12/2019
NIH/NCI Physical Sciences in Oncology Network (PS-ON), Steering Committee Co-Chair
  9/2015–12/2023
NIH/NCI PS-ON, Steering Committee Member
11/2023

NIH/NCI Cancer Systems Biology Consortium (CSBC) and PS-ON Joint Meeting (Bethesda, MD), Co-Chair, Co-Organizer, and Invited Speaker
  7/2023, 6/2022, 7/2021, 6/2017, 6/2016, 6/2015, 6/2014
International High-Performance Computing (HPC) Summer School on HPC Challenges in Computational Sciences (Atlanta, GA; Athens, Greece; Virtual; Boulder, CO; Ljubljana, Slovenia; Toronto, Canada; Budapest, Hungary), Mentor and Speaker
  9/2022, 9/2019
NIH/NCI Physical Sciences in Oncology Symposium (Virtual; Minneapolis, MN), Co-Chair, Co-Organizer, and Panel Moderator
  9/2020

NIH/NCI, Decade of the PS-ON at the NCI Virtual Symposium, Co-Chair, Co-Organizer, and Invited Speaker
  6/2020


  
2020 American Association for Cancer Research (AACR) Virtual Annual Meeting II, Education Session Co-Chair, Co-Organizer, and Invited Speaker "Artificial Intelligence and Machine Learning from Research to the Cancer Clinic"20
10/2018

2018 Biomedical Engineering Society (BMES) Annual Meeting (Atlanta, GA), Speaker and Panelist, "Physical Sciences in Oncology"
  5/2018


2018 SIAM Conference on Applied Linear Algebra (SIAM-ALA18) (Hong Kong, China), Three-Session Minisymposium Chair and Co-Organizer, "Discovery from Data"
  2/2017

1st Gordon Research Conference on the Physics of Cancer (Galveston, TX), Session Chair
10/2016


American Association of Physicists in Medicine (AAPM) Broadcast (Boston, MA), Panelist, "Provocative Questions for Medical Physics in Oncology"
  9/2014



5th Association for Computing Machinery (ACM) Conference on Bioinformatics, Computational Biology and Health Informatics (ACM-BCB) (Newport Beach, CA), Panel Co-Chair, Co-Organizer, and Participant, "Bioinformatics, Computational and Systems Biology"
  7/2014



2014 SIAM Annual Meeting (Chicago, IL), Three-Session Minisymposium Chair, Organizer, and Speaker, "Discovery from Data:" "I. Mathematical Patterns in Nature," "II. Cancer Genomic Signals and Systems," "III. Decompositions for Big Data Applications"
  9/2013

2013 BMES Annual Meeting (Atlanta, GA), Track Chair, Organizer, and Speaker, "Bioinformatics, Computational and Systems Biology"
  7/2013

NSF–Japan Society for the Promotion of Science (JSPS) Connections 2013 Symposium (Washington, DC), Participant
  2/2009

NSF, Workshop Participant, "Future Directions in Tensor-Based Computation and Modeling"
  2/2008

SXSVD (South by SVD): Gene H. Golub's World Day Celebration (Austin, TX), Chair and Organizer
  1/2008

NIH/National Human Genome Research Institute (NHGRI), Planning Meeting Participant, "The Cancer Genome Atlas (TCGA) Data Portal"
  8/2006
NSF, Workshop Participant, "Petascale Computing in the Biosciences"
  7/2006


17th International Symposium on the Mathematical Theory of Networks and Systems (MTNS) (Kyoto, Japan), Invited Session Chair and Organizer, "Genomic Signals and Systems"
12/2001

NIH/NHGRI, Planning Meeting Participant, "A Vision for the Future of Genomics Research"




2015–2023  NCI U01 CA-20214421,22 $3,395,98623
2009–2015   NSF CAREER DMS-084717324     $400,05325
2007–2015   NHGRI R01 HG-00430226 $1,768,52527
2000–2005   NHGRI K01 HG-00003828     $527,36729
1999–2003   DE FG03-99ER6283630     $100,000