SGD_YORF NAME Aliases PROCESS FUNCTION CELLULAR_COMPONENT CELL_CYCLE_CLASSIFICATION DNA_DAMAGE_CLASSIFICATION Chromosome Start End LAD_Probe SGD_ID Type Description YAL001C TFC3 TSV115|FUN24 transcription_initiation_from_RNA_polymerase_III_promoter RNA_polymerase_III_transcription_factor_activity mitochondrion* None Up 1 151168 147596 YAL001C S000000001 "ORF,_Verified" Largest_of_six_subunits_of_the_RNA_polymerase_III_transcription_initiation_factor_complex_(TFIIIC);_part_of_the_TauB_domain_of_TFIIIC_that_binds_DNA_at_the_BoxB_promoter_sites_of_tRNA_and_similar_genes;_cooperates_with_Tfc6p_in_DNA_binding YAL002W VPS8 VPT8|FUN15 late_endosome_to_vacuole_transport molecular_function_unknown membrane_fraction None None 1 143709 147533 YAL002W S000000002 "ORF,_Verified" Membrane-associated_protein_that_interacts_with_Vps21p_to_facilitate_soluble_vacuolar_protein_localization;_component_of_the_CORVET_complex;_required_for_localization_and_trafficking_of_the_CPY_sorting_receptor;_contains_RING_finger_motif YAL003W EFB1 TEF5 translational_elongation translation_elongation_factor_activity ribosome* None None 1 142176 143162 YAL003W S000000003 "ORF,_Verified" "Translation_elongation_factor_1_beta;_stimulates_nucleotide_exchange_to_regenerate_EF-1_alpha-GTP_for_the_next_elongation_cycle;_part_of_the_EF-1_complex,_which_facilitates_binding_of_aminoacyl-tRNA_to_the_ribosomal_A_site" YAL005C SSA1 YG100 protein_folding* ATPase_activity* cytoplasm* None Up 1 141433 139505 YAL005C S000000004 "ORF,_Verified" "ATPase_involved_in_protein_folding_and_nuclear_localization_signal_(NLS)-directed_nuclear_transport;_member_of_heat_shock_protein_70_(HSP70)_family;_forms_a_chaperone_complex_with_Ydj1p;_localized_to_the_nucleus,_cytoplasm,_and_cell_wall" YAL007C ERP2 None ER_to_Golgi_transport molecular_function_unknown COPII-coated_vesicle None None 1 138347 137700 YAL007C S000000005 "ORF,_Verified" "Protein_that_forms_a_heterotrimeric_complex_with_Erp1p,_Emp24p,_and_Erv25p;_member,_along_with_Emp24p_and_Erv25p,_of_the_p24_family_involved_in_ER_to_Golgi_transport_and_localized_to_COPII-coated_vesicles" YAL008W FUN14 None biological_process_unknown molecular_function_unknown mitochondrion None None 1 136916 137512 YAL008W S000000006 "ORF,_Verified" Mitochondrial_protein_of_unknown_function YAL009W SPO7 None sporulation_(sensu_Fungi)* molecular_function_unknown integral_to_membrane* None None 1 135856 136635 YAL009W S000000007 "ORF,_Verified" "Regulatory_subunit_of_Nem1p-Spo7p_phosphatase_holoenzyme,_which_regulates_nuclear_growth_by_controlling_recruitment_of_Pah1p_onto_promoters_of_phospholipid_biosynthetic_genes;_required_for_normal_nuclear_envelope_morphology_and_sporulation" YAL010C MDM10 FUN37 protein_complex_assembly* molecular_function_unknown mitochondrial_outer_membrane* None None 1 135667 134186 YAL010C S000000008 "ORF,_Verified" Subunit_of_both_the_Mdm10-Mdm12-Mmm1_complex_and_the_mitochondrial_sorting_and_assembly_machinery_(SAM_complex);_functions_in_both_the_general_and_Tom40p-specific_pathways_for_import_and_assembly_of_outer_membrane_beta-barrel_proteins YAL011W SWC3 SWC1 chromatin_remodeling* molecular_function_unknown nucleus* None None 1 132202 134079 YAL011W S000000009 "ORF,_Verified" "Protein_of_unknown_function,_component_of_the_SWR1_complex,_which_exchanges_histone_variant_H2AZ_(Htz1p)_for_chromatin-bound_histone_H2A;_required_for_formation_of_nuclear-associated_array_of_smooth_endoplasmic_reticulum_known_as_karmellae" YAL012W CYS3 STR1|FUN35|CYI1 sulfur_amino_acid_metabolism* cystathionine_gamma-lyase_activity cytoplasm None None 1 130802 131986 YAL012W S000000010 "ORF,_Verified" "Cystathionine_gamma-lyase,_catalyzes_one_of_the_two_reactions_involved_in_the_transsulfuration_pathway_that_yields_cysteine_from_homocysteine_with_the_intermediary_formation_of_cystathionine" YAL013W DEP1 FUN54 regulation_of_transcription_from_RNA_polymerase_II_promoter* molecular_function_unknown cellular_component_unknown None None 1 129271 130533 YAL013W S000000011 "ORF,_Verified" "Transcriptional_modulator_involved_in_regulation_of_structural_phospholipid_biosynthesis_genes_and_metabolically_unrelated_genes,_as_well_as_maintenance_of_telomeres,_mating_efficiency,_and_sporulation" YAL014C SYN8 SLT2|UIP2 transport SNAP_receptor_activity endosome None Up 1 129020 128253 YAL014C S000000012 "ORF,_Verified" Endosomal_SNARE_related_to_mammalian_syntaxin_8 YAL015C NTG1 SCR1|FUN33 DNA_repair* DNA-(apurinic_or_apyrimidinic_site)_lyase_activity* nucleus* None Up 1 128103 126904 YAL015C S000000013 "ORF,_Verified" "DNA_N-glycosylase_and_apurinic/apyrimidinic_(AP)_lyase_involved_in_base_excision_repair,_localizes_to_the_nucleus_and_mitochondrion" YAL016W TPD3 FUN32 protein_biosynthesis* protein_phosphatase_type_2A_activity cytoplasm* None None 1 124880 126787 YAL016W S000000014 "ORF,_Verified" "Regulatory_subunit_A_of_the_heterotrimeric_protein_phosphatase_2A,_which_also_contains_regulatory_subunit_Cdc55p_and_either_catalytic_subunit_Pph21p_or_Pph22p;_required_for_cell_morphogenesis_and_for_transcription_by_RNA_polymerase_III" YAL018C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 119542 118565 YAL018C S000000016 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YAL019W FUN30 None chromosome_organization_and_biogenesis_(sensu_Eukaryota) molecular_function_unknown nucleus* None None 1 114920 118315 YAL019W S000000017 "ORF,_Verified" "Protein_whose_overexpression_affects_chromosome_stability,_potential_Cdc28p_substrate;_homolog_of_Snf2p;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YAL020C ATS1 KTI13|FUN28 budding_cell_bud_growth* molecular_function_unknown cytoplasm None None 1 114616 113615 YAL020C S000000018 "ORF,_Verified" "Protein_required,_with_Elongator_complex,_Kti11p,_and_Kti12p,_for_modification_of_wobble_nucleosides_in_tRNA;_has_a_potential_role_in_regulatory_interactions_between_microtubules_and_the_cell_cycle" YAL022C FUN26 None nucleoside_transport nucleoside_transporter_activity membrane* G2/M None 1 110431 108878 YAL022C S000000020 "ORF,_Verified" Nucleoside_transporter_with_broad_nucleoside_selectivity;_localized_to_intracellular_membranes YAL023C PMT2 FUN25 protein_amino_acid_O-linked_glycosylation dolichyl-phosphate-mannose-protein_mannosyltransferase_activity endoplasmic_reticulum None None 1 108552 106273 YAL023C S000000021 "ORF,_Verified" "Protein_O-mannosyltransferase,_transfers_mannose_residues_from_dolichyl_phosphate-D-mannose_to_protein_serine/threonine_residues;_acts_in_a_complex_with_Pmt1p,_can_instead_interact_with_Pmt5p_in_some_conditions;_target_for_new_antifungals" YAL024C LTE1 MSI2 regulation_of_exit_from_mitosis guanyl-nucleotide_exchange_factor_activity bud None None 1 105873 101566 YAL024C S000000022 "ORF,_Verified" "Putative_GDP/GTP_exchange_factor_required_for_mitotic_exit_at_low_temperatures;_acts_as_a_guanine_nucleotide_exchange_factor_(GEF)_for_Tem1p,_which_is_a_key_regulator_of_mitotic_exit;_physically_associates_with_Ras2p-GTP" YAL025C MAK16 None ribosomal_large_subunit_biogenesis molecular_function_unknown nucleolus None Down 1 101146 100226 YAL025C S000000023 "ORF,_Verified" "Essential_nuclear_protein,_constituent_of_66S_pre-ribosomal_particles;_required_for_maturation_of_25S_and_5.8S_rRNAs;_required_for_maintenance_of_M1_satellite_double-stranded_RNA_of_the_L-A_virus" YAL026C DRS2 SWA3|FUN38 processing_of_20S_pre-rRNA* ATPase_activity* plasma_membrane* None None 1 99698 95631 YAL026C S000000024 "ORF,_Verified" Aminophospholipid_translocase_(flippase)_that_maintains_membrane_lipid_asymmetry_in_post-Golgi_secretory_vessicles;_contributes_to_clathrin-coated_vesicle_formation_and_endocytosis;_mutations_in_human_homolog_ATP8B1_result_in_liver_disease YAL027W SAW1 None biological_process_unknown molecular_function_unknown nucleus None None 1 94688 95473 YAL027W S000000025 "ORF,_Verified" Catalyzes_3'-nonhomologous_tail_removal_of_Rad1p/Rad10p-dependent_single-strand_annealing_recombination_intermediates;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus;_YAL027W_is_a_non-essential_gene YAL028W FRT2 HPH2 response_to_stress molecular_function_unknown endoplasmic_reticulum None None 1 92901 94487 YAL028W S000000026 "ORF,_Verified" "Tail-anchored_endoplasmic_reticulum_membrane_protein,_interacts_with_homolog_Frt1p_but_is_not_a_substrate_of_calcineurin_(unlike_Frt1p),_promotes_growth_in_conditions_of_high_Na+,_alkaline_pH,_or_cell_wall_stress;_potential_Cdc28p_substrate" YAL031C GIP4 FUN21 biological_process_unknown molecular_function_unknown cytoplasm None None 1 87032 84750 YAL031C S000000029 "ORF,_Verified" Cytoplasmic_Glc7-interacting_protein_whose_overexpression_relocalizes_Glc7p_from_the_nucleus_and_prevents_chromosome_segregation;_potential_Cdc28p_substrate YAL032C PRP45 FUN20 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter transcriptional_activator_activity nucleus None None 1 84475 83336 YAL032C S000000030 "ORF,_Verified" Protein_required_for_pre-mRNA_splicing;_associates_with_the_spliceosome_and_interacts_with_splicing_factors_Prp22p_and_Prp46p;_orthologous_to_human_transcriptional_coactivator_SKIP_and_can_activate_transcription_of_a_reporter_gene YAL033W POP5 FUN53 rRNA_processing* ribonuclease_P_activity* ribonuclease_MRP_complex* None None 1 82707 83228 YAL033W S000000031 "ORF,_Verified" "Subunit_of_both_RNase_MRP,_which_cleaves_pre-rRNA,_and_nuclear_RNase_P,_which_cleaves_tRNA_precursors_to_generate_mature_5'_ends" YAL034C FUN19 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 81952 80711 YAL034C S000002134 "ORF,_Verified" Non-essential_protein_of_unknown_function YAL034W-A MTW1 NSL2|DSN3 chromosome_segregation molecular_function_unknown spindle_pole* None None 1 79719 80588 YAL034W-A S000000032 "ORF,_Verified" Essential_component_of_the_MIND_kinetochore_complex_(Mtw1p_Including_Nnf1p-Nsl1p-Dsn1p)_which_joins_kinetochore_subunits_contacting_DNA_to_those_contacting_microtubules;_critical_to_kinetochore_assembly YAL036C RBG1 FUN11 biological_process_unknown GTP_binding cytoplasm None None 1 76153 75044 YAL036C S000000034 "ORF,_Verified" Member_of_the_DRG_family_of_GTP-binding_proteins;_interacts_with_translating_ribosomes_and_with_Tma46p YAL037W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 74021 74824 YAL037W S000000035 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YAL038W CDC19 PYK1 glycolysis* pyruvate_kinase_activity cytosol None None 1 71787 73289 YAL038W S000000036 "ORF,_Verified" "Pyruvate_kinase,_functions_as_a_homotetramer_in_glycolysis_to_convert_phosphoenolpyruvate_to_pyruvate,_the_input_for_aerobic_(TCA_cycle)_or_anaerobic_(glucose_fermentation)_respiration" YAL039C CYC3 None cytochrome_c-heme_linkage holocytochrome-c_synthase_activity mitochondrial_intermembrane_space None None 1 69526 68717 YAL039C S000000037 "ORF,_Verified" "Cytochrome_c_heme_lyase_(holocytochrome_c_synthase),_attaches_heme_to_apo-cytochrome_c_(Cyc1p_or_Cyc7p)_in_the_mitochondrial_intermembrane_space;_human_ortholog_may_have_a_role_in_microphthalmia_with_linear_skin_defects_(MLS)" YAL041W CDC24 CLS4 establishment_of_cell_polarity_(sensu_Fungi)* signal_transducer_activity* nucleus* None None 1 62841 65405 YAL041W S000000039 "ORF,_Verified" "Guanine_nucleotide_exchange_factor_(GEF_or_GDP-release_factor)_for_Cdc42p;_required_for_polarity_establishment_and_maintenance,_and_mutants_have_morphological_defects_in_bud_formation_and_shmooing" YAL043C PTA1 FUN39 tRNA_processing* RNA_binding mRNA_cleavage_and_polyadenylation_specificity_factor_complex* None None 1 61053 58696 YAL043C S000000041 "ORF,_Verified" "Subunit_of_holo-CPF,_a_multiprotein_complex_and_functional_homolog_of_mammalian_CPSF,_required_for_the_cleavage_and_polyadenylation_of_mRNA_and_snoRNA_3'_ends;_involved_in_pre-tRNA_processing;_binds_to_the_phosphorylated_CTD_of_RNAPII" YAL044C GCV3 None one-carbon_compound_metabolism* glycine_dehydrogenase_(decarboxylating)_activity mitochondrion* None None 1 58463 57951 YAL044C S000000042 "ORF,_Verified" "H_subunit_of_the_mitochondrial_glycine_decarboxylase_complex,_required_for_the_catabolism_of_glycine_to_5,10-methylene-THF;_expression_is_regulated_by_levels_of_levels_of_5,10-methylene-THF_in_the_cytoplasm" YAL046C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 57386 57030 YAL046C S000000044 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation) YAL047C SPC72 LDB4 mitotic_sister_chromatid_segregation* structural_constituent_of_cytoskeleton outer_plaque_of_spindle_pole_body None None 1 56858 54990 YAL047C S000000045 "ORF,_Verified" "Component_of_the_cytoplasmic_Tub4p_(gamma-tubulin)_complex,_binds_spindle_pole_bodies_and_links_them_to_microtubules;_has_roles_in_astral_microtubule_formation_and_stabilization" YAL048C GEM1 GON1 vesicle-mediated_transport GTPase_activity mitochondrial_outer_membrane None None 1 54790 52802 YAL048C S000000046 "ORF,_Verified" "Evolutionarily-conserved_tail-anchored_outer_mitochondrial_membrane_GTPase_which_regulates_mitochondrial_morphology;_cells_lacking_Gem1p_contain_collapsed,_globular,_or_grape-like_mitochondria;_not_required_for_pheromone-induced_cell_death" YAL051W OAF1 YAF1 peroxisome_organization_and_biogenesis* DNA_binding* nucleus None None 1 48565 51708 YAL051W S000000048 "ORF,_Verified" "Oleate-activated_transcription_factor,_acts_alone_and_as_a_heterodimer_with_Pip2p;_activates_genes_involved_in_beta-oxidation_of_fatty_acids_and_peroxisome_organization_and_biogenesis" YAL055W PEX22 YAF5 protein_targeting_to_peroxisome molecular_function_unknown peroxisome None None 1 42178 42720 YAL055W S000000051 "ORF,_Verified" "Putative_peroxisomal_membrane_protein_required_for_import_of_peroxisomal_proteins,_functionally_complements_a_Pichia_pastoris_pex22_mutation" YAL058W CNE1 FUN48 protein_folding* unfolded_protein_binding integral_to_endoplasmic_reticulum_membrane None None 1 37465 38973 YAL058W S000000054 "ORF,_Verified" "Calnexin;_integral_membrane_ER_chaperone_involved_in_folding_and_quality_control_of_glycoproteins;_chaperone_activity_is_inhibited_by_Mpd1p,_with_which_Cne1p_interacts;_24%_identical_to_mammalian_calnexin;_Ca+_binding_not_yet_shown_in_yeast" YAL059W ECM1 None cell_wall_organization_and_biogenesis* molecular_function_unknown nucleus* None None 1 36510 37148 YAL059W S000000055 "ORF,_Verified" "Protein_of_unknown_function,_localized_in_the_nucleoplasm_and_the_nucleolus,_genetically_interacts_with_MTR2_in_60S_ribosomal_protein_subunit_export" YAL060W BDH1 None butanediol_fermentation "(R,R)-butanediol_dehydrogenase_activity" cytoplasm None Up 1 35156 36304 YAL060W S000000056 "ORF,_Verified" "NAD-dependent_(R,R)-butanediol_dehydrogenase,_catalyzes_oxidation_of_(R,R)-2,3-butanediol_to_(3R)-acetoin,_oxidation_of_meso-butanediol_to_(3S)-acetoin,_and_reduction_of_acetoin;_enhances_use_of_2,3-butanediol_as_an_aerobic_carbon_source" YAL061W BDH2 None biological_process_unknown "oxidoreductase_activity,_acting_on_the_CH-OH_group_of_donors,_NAD_or_NADP_as_acceptor" cytoplasm* None None 1 33449 34702 YAL061W S000000057 "ORF,_Uncharacterized" Putative_medium-chain_alcohol_dehydrogenase_with_similarity_to_BDH1;_transcription_induced_by_constitutively_active_PDR1_and_PDR3;_BDH2_is_an_essential_gene YAL062W GDH3 FUN51 glutamate_biosynthesis glutamate_dehydrogenase_activity nucleus* None None 1 31568 32941 YAL062W S000000058 "ORF,_Verified" "NADP(+)-dependent_glutamate_dehydrogenase,_synthesizes_glutamate_from_ammonia_and_alpha-ketoglutarate;_rate_of_alpha-ketoglutarate_utilization_differs_from_Gdh1p;_expression_regulated_by_nitrogen_and_carbon_sources" YAL064C-A None YAL065C-A biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 13744 13364 YAL064C-A S000002140 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YAL064C-A_is_not_an_essential_gene YAL064W-B None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 12047 12427 YAL064W-B S000002141 "ORF,_Uncharacterized" Fungal-specific_protein_of_unknown_function YAL065C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 11952 11566 YAL065C S000001817 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_has_homology_to_FLO1;_possible_pseudogene YAL068C PAU8 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 2169 1807 YAL068C S000002142 "ORF,_Uncharacterized" Hypothetical_protein YAR002C-A ERP1 None ER_to_Golgi_transport molecular_function_unknown mitochondrion* None None 1 154726 154067 YAR002C-A S000002129 "ORF,_Verified" "Protein_that_forms_a_heterotrimeric_complex_with_Erp2p,_Emp24p,_and_Erv25p;_member,_along_with_Emp24p_and_Erv25p,_of_the_p24_family_involved_in_ER_to_Golgi_transport_and_localized_to_COPII-coated_vesicles" YAR002W NUP60 None nucleocytoplasmic_transport* structural_constituent_of_nuclear_pore nuclear_pore None None 1 152259 153878 YAR002W S000000063 "ORF,_Verified" "Subunit_of_the_nuclear_pore_complex_(NPC),_functions_to_anchor_Nup2p_to_the_NPC_in_a_process_controlled_by_the_nucleoplasmic_concentration_of_Gsp1p-GTP;_potential_Cdc28p_substrate;_involved_in_telomere_maintenance" YAR003W SWD1 SAF49|CPS50|FUN16 chromatin_silencing_at_telomere* histone_lysine_N-methyltransferase_activity_(H3-K4_specific) COMPASS_complex G1 None 1 155007 156287 YAR003W S000000064 "ORF,_Verified" "Subunit_of_the_COMPASS_(Set1C)_complex,_which_methylates_histone_H3_on_lysine_4_and_is_required_in_transcriptional_silencing_near_telomeres;_WD40_beta_propeller_superfamily_member_with_similarity_to_mammalian_Rbbp7" YAR007C RFA1 RPA1|FUN3|BUF2 DNA_recombination* single-stranded_DNA_binding* cytoplasm* G1 Up 1 158621 156756 YAR007C S000000065 "ORF,_Verified" "Subunit_of_heterotrimeric_Replication_Protein_A_(RPA),_which_is_a_highly_conserved_single-stranded_DNA_binding_protein_involved_in_DNA_replication,_repair,_and_recombination" YAR008W SEN34 FUN4 tRNA_splicing tRNA-intron_endonuclease_activity mitochondrial_outer_membrane* G1 None 1 158967 159794 YAR008W S000000066 "ORF,_Verified" "Subunit_of_the_tRNA_splicing_endonuclease,_which_is_composed_of_Sen2p,_Sen15p,_Sen34p,_and_Sen54p;_Sen34p_contains_the_active_site_for_tRNA_3'_splice_site_cleavage_and_has_similarity_to_Sen2p_and_to_Archaeal_tRNA_splicing_endonuclease" YAR009C None YARCTyB1-1 None None None None None 1 164188 160598 YAR009C S000000067 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_in_YARCTY1-1_TYB_is_mutant_and_probably_non-functional YAR010C None YARCTyA1-1 None None None None None 1 165867 164545 YAR010C S000000068 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_in_YARCTY1-1_TYB_is_mutant_and_probably_non-functional YAR014C BUD14 None "regulation_of_transcription,_DNA-dependent*" protein_phosphatase_type_1_regulator_activity bud_neck* None None 1 168866 166743 YAR014C S000000069 "ORF,_Verified" "Protein_involved_in_bud-site_selection,_Bud14p-Glc7p_complex_functions_as_a_cortical_regulator_of_dynein;_diploid_mutants_display_a_random_budding_pattern_instead_of_the_wild-type_bipolar_pattern" YAR015W ADE1 None de_novo'_IMP_biosynthesis* phosphoribosylaminoimidazolesuccinocarboxamide_synthase_activity cytoplasm* None None 1 169370 170290 YAR015W S000000070 "ORF,_Verified" "N-succinyl-5-aminoimidazole-4-carboxamide_ribotide_(SAICAR)_synthetase,_required_for_'de_novo'_purine_nucleotide_biosynthesis;_red_pigment_accumulates_in_mutant_cells_deprived_of_adenine" YAR018C KIN3 NPK1|FUN52 chromosome_segregation protein_kinase_activity cellular_component_unknown G2/M None 1 171698 170391 YAR018C S000000071 "ORF,_Verified" Nonessential_protein_kinase_with_unknown_cellular_role YAR019C CDC15 LYT1 protein_amino_acid_phosphorylation* protein_kinase_activity bud_neck* None None 1 175133 172209 YAR019C S000000072 "ORF,_Verified" Protein_kinase_of_the_Mitotic_Exit_Network_that_is_localized_to_the_spindle_pole_bodies_at_late_anaphase;_promotes_mitotic_exit_by_directly_switching_on_the_kinase_activity_of_Dbf2p YAR020C PAU7 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 177021 176854 YAR020C S000000073 "ORF,_Verified" "Part_of_23-member_seripauperin_multigene_family,_active_during_alcoholic_fermentation,_regulated_by_anaerobiosis,_inhibited_by_oxygen,_repressed_by_heme" YAR027W UIP3 None biological_process_unknown molecular_function_unknown nuclear_envelope None None 1 183764 184471 YAR027W S000000075 "ORF,_Verified" Putative_integral_membrane_protein_of_unknown_function;_interacts_with_Ulp1p_at_the_nuclear_periphery;_member_of_DUP240_gene_family YAR028W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 184886 185590 YAR028W S000000076 "ORF,_Uncharacterized" "Putative_integral_membrane_protein,_member_of_DUP240_gene_family;_GFP-fusion_protein_is_induced_in_response_to_the_DNA-damaging_agent_MMS" YAR029W None None biological_process_unknown molecular_function_unknown cytoplasm None None 1 186315 186539 YAR029W S000000077 "ORF,_Uncharacterized" Member_of_DUP240_gene_family_but_contains_no_transmembrane_domains;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern YAR031W PRM9 None vesicle_organization_and_biogenesis molecular_function_unknown endoplasmic_reticulum* None None 1 186830 187726 YAR031W S000000078 "ORF,_Verified" "Pheromone-regulated_protein_with_3_predicted_transmembrane_segments_and_an_FF_sequence,_a_motif_involved_in_COPII_binding;_member_of_DUP240_gene_family" YAR033W MST28 None vesicle_organization_and_biogenesis protein_binding endoplasmic_reticulum* None None 1 188101 188805 YAR033W S000000079 "ORF,_Verified" "Putative_integral_membrane_protein,_involved_in_vesicle_formation;_forms_complex_with_Mst27p;_member_of_DUP240_gene_family;_binds_COPI_and_COPII_vesicles" YAR035W YAT1 None alcohol_metabolism* carnitine_O-acetyltransferase_activity mitochondrion None None 1 190187 192250 YAR035W S000000080 "ORF,_Verified" "Outer_mitochondrial_carnitine_acetyltransferase,_minor_ethanol-inducible_enzyme_involved_in_transport_of_activated_acyl_groups_from_the_cytoplasm_into_the_mitochondrial_matrix;_phosphorylated" YAR050W FLO1 FLO4|FLO2 flocculation_(sensu_Saccharomyces) mannose_binding cell_wall_(sensu_Fungi) None None 1 203394 208007 YAR050W S000000084 "ORF,_Verified" "Lectin-like_protein_involved_in_flocculation,_cell_wall_protein_that_binds_to_mannose_chains_on_the_surface_of_other_cells,_confers_floc-forming_ability_that_is_chymotrypsin_sensitive_and_heat_resistant;_similar_to_Flo5p" YAR064W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 220189 220488 YAR064W S000000089 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YAR068W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 1 222397 222882 YAR068W S000000091 "ORF,_Uncharacterized" Fungal-specific_protein_of_unknown_function;_induced_in_respiratory-deficient_cells YAR071W PHO11 None phosphate_metabolism acid_phosphatase_activity extracellular_region G2/M None 1 225451 226854 YAR071W S000000094 "ORF,_Verified" "One_of_three_repressible_acid_phosphatases,_a_glycoprotein_that_is_transported_to_the_cell_surface_by_the_secretory_pathway;_induced_by_phosphate_starvation_and_coordinately_regulated_by_PHO4_and_PHO2" YBL001C ECM15 None cell_wall_organization_and_biogenesis molecular_function_unknown cytoplasm* None None 2 237469 237155 YBL001C S000000097 "ORF,_Verified" "Non-essential_protein_of_unknown_function,_likely_exists_as_tetramer,_may_be_regulated_by_the_binding_of_small-molecule_ligands_(possibly_sulfate_ions),_may_have_a_role_in_yeast_cell-wall_biogenesis" YBL002W HTB2 None chromatin_assembly_or_disassembly DNA_binding nuclear_nucleosome S Down 2 236495 236890 YBL002W S000000098 "ORF,_Verified" "Histone_H2B,_core_histone_protein_required_for_chromatin_assembly_and_chromosome_function;_nearly_identical_to_HTB1;_Rad6p-Bre1p-Lge1p_mediated_ubiquitination_regulates_transcriptional_activation,_meiotic_DSB_formation_and_H3_methylation" YBL003C HTA2 H2A2 DNA_repair* DNA_binding nuclear_nucleosome S Down 2 235795 235397 YBL003C S000000099 "ORF,_Verified" "Histone_H2A,_core_histone_protein_required_for_chromatin_assembly_and_chromosome_function;_one_of_two_nearly_identical_(see_also_HTA1)_subtypes;_DNA_damage-dependent_phosphorylation_by_Mec1p_facilitates_DNA_repair;_acetylated_by_Nat4p" YBL004W UTP20 None 35S_primary_transcript_processing snoRNA_binding cytoplasm* None None 2 227639 235120 YBL004W S000000100 "ORF,_Verified" "Component_of_the_small-subunit_(SSU)_processome,_which_is_involved_in_the_biogenesis_of_the_18S_rRNA" YBL005W PDR3 TPE2|AMY2 regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* cytoplasm* None None 2 217473 220403 YBL005W S000000101 "ORF,_Verified" "Transcriptional_activator_of_the_pleiotropic_drug_resistance_network,_regulates_expression_of_ATP-binding_cassette_(ABC)_transporters_through_binding_to_cis-acting_sites_known_as_PDREs_(PDR_responsive_elements)" YBL005W-A None None None None None None None 2 221333 222655 YBL005W-A S000002146 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YBL005W-B None None None None None None None 2 221333 226601 YBL005W-B S000002147 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YBL007C SLA1 None cell_wall_organization_and_biogenesis* "protein_binding,_bridging*" actin_cortical_patch None None 2 216369 212635 YBL007C S000000103 "ORF,_Verified" Cytoskeletal_protein_binding_protein_required_for_assembly_of_the_cortical_actin_cytoskeleton;_interacts_with_proteins_regulating_actin_dynamics_and_proteins_required_for_endocytosis;_found_in_the_nucleus_and_cell_cortex;_has_3_SH3_domains YBL008W HIR1 None regulation_of_transcription_from_RNA_polymerase_II_promoter transcription_corepressor_activity nucleus* None None 2 209656 212178 YBL008W S000000104 "ORF,_Verified" "Subunit_of_the_HIR_complex,_a_nucleosome_assembly_complex_involved_in_regulation_of_histone_gene_transcription;_contributes_to_nucleosome_formation,_heterochromatic_gene_silencing,_and_formation_of_functional_kinetochores" YBL010C None None biological_process_unknown molecular_function_unknown clathrin-coated_vesicle None None 2 206952 206110 YBL010C S000000106 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_colocalizes_with_clathrin-coated_vesicles YBL011W SCT1 GAT2 phospholipid_biosynthesis glycerol-3-phosphate_O-acyltransferase_activity endoplasmic_reticulum None None 2 203541 205820 YBL011W S000000107 "ORF,_Verified" "Glycerol_3-phosphate/dihydroxyacetone_phosphate_dual_substrate-specific_sn-1_acyltransferase_of_the_glycerolipid_biosynthesis_pathway,_prefers_16-carbon_fatty_acids,_similar_to_Gpt2p,_gene_is_constitutively_transcribed" YBL014C RRN6 None transcription_from_RNA_polymerase_I_promoter RNA_polymerase_I_transcription_factor_activity RNA_polymerase_I_transcription_factor_complex None None 2 201751 199067 YBL014C S000000110 "ORF,_Verified" "Protein_involved_in_the_transcription_of_35S_rRNA_genes_by_RNA_polymerase_I;_component_of_the_core_factor_(CF)_complex_also_composed_of_Rrn11p,_Rrn7p_and_TATA-binding_protein" YBL015W ACH1 None acetate_metabolism* acetyl-CoA_hydrolase_activity mitochondrion* None None 2 194125 195705 YBL015W S000000111 "ORF,_Verified" "Acetyl-coA_hydrolase,_primarily_localized_to_mitochondria;_phosphorylated;_required_for_acetate_utilization_and_for_diploid_pseudohyphal_growth" YBL016W FUS3 DAC2 protein_amino_acid_phosphorylation* MAP_kinase_activity cytoplasm* None None 2 192454 193515 YBL016W S000000112 "ORF,_Verified" "Mitogen-activated_serine/threonine_protein_kinase_involved_in_mating;_phosphoactivated_by_Ste7p;_substrates_include_Ste12p,_Far1p,_Bni1p,_Sst2p;_inhibits_invasive_growth_during_mating_by_phosphorylating_Tec1p,_promoting_its_degradation" YBL018C POP8 None rRNA_processing* ribonuclease_P_activity* ribonuclease_MRP_complex* None None 2 186477 186001 YBL018C S000000114 "ORF,_Verified" "Subunit_of_both_RNase_MRP,_which_cleaves_pre-rRNA,_and_nuclear_RNase_P,_which_cleaves_tRNA_precursors_to_generate_mature_5'_ends" YBL019W APN2 ETH1 DNA_repair phosphodiesterase_I_activity* nucleus None None 2 184356 185918 YBL019W S000000115 "ORF,_Verified" Class_II_abasic_(AP)_endonuclease_involved_in_repair_of_DNA_damage;_homolog_of_human_HAP1_and_E._coli_exoIII YBL021C HAP3 None transcription* transcriptional_activator_activity nucleus* None None 2 182097 181663 YBL021C S000000117 "ORF,_Verified" "Subunit_of_the_heme-activated,_glucose-repressed_Hap2p/3p/4p/5p_CCAAT-binding_complex,_a_transcriptional_activator_and_global_regulator_of_respiratory_gene_expression;_contains_sequences_contributing_to_both_complex_assembly_and_DNA_binding" YBL022C PIM1 LON1 proteolysis* ATP-dependent_peptidase_activity mitochondrial_matrix None None 2 181278 177877 YBL022C S000000118 "ORF,_Verified" "ATP-dependent_Lon_protease,_involved_in_degradation_of_misfolded_proteins_in_mitochondria;_required_for_biogenesis_and_maintenance_of_mitochondria" YBL024W NCL1 TRM4 tRNA_methylation tRNA_(cytosine-5-)-methyltransferase_activity nucleus None None 2 172537 174591 YBL024W S000000120 "ORF,_Verified" "S-adenosyl-L-methionine-dependent_tRNA:_m5C-methyltransferase,_methylates_cytosine_to_m5C_at_several_positions_in_tRNAs_and_intron-containing_pre-tRNAs;_similar_to_Nop2p_and_human_proliferation_associated_nucleolar_protein_p120" YBL025W RRN10 None transcription_from_RNA_polymerase_I_promoter RNA_polymerase_I_transcription_factor_activity* RNA_polymerase_I_upstream_activating_factor_complex None None 2 171484 171921 YBL025W S000000121 "ORF,_Verified" "Protein_involved_in_promoting_high_level_transcription_of_rDNA,_subunit_of_UAF_(upstream_activation_factor)_for_RNA_polymerase_I" YBL026W LSM2 SNP3|SMX5 "nuclear_mRNA_splicing,_via_spliceosome*" RNA_binding* nucleolus* None None 2 170626 171041 YBL026W S000000122 "ORF,_Verified" "Lsm_(Like_Sm)_protein;_part_of_heteroheptameric_complexes_(Lsm2p-7p_and_either_Lsm1p_or_8p):_cytoplasmic_Lsm1p_complex_involved_in_mRNA_decay;_nuclear_Lsm8p_complex_part_of_U6_snRNP_and_possibly_involved_in_processing_tRNA,_snoRNA,_and_rRNA" YBL027W RPL19B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 2 168426 169379 YBL027W S000000123 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl19Ap_and_has_similarity_to_rat_L19_ribosomal_protein;_rpl19a_and_rpl19b_single_null_mutations_result_in_slow_growth,_while_the_double_null_mutation_is_lethal" YBL028C None None biological_process_unknown molecular_function_unknown nucleus* None None 2 167841 167521 YBL028C S000000124 "ORF,_Verified" Protein_of_unknown_function_that_may_interact_with_ribosomes;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleolus;_predicted_to_be_involved_in_ribosome_biogenesis YBL031W SHE1 None biological_process_unknown molecular_function_unknown microtubule_cytoskeleton None None 2 161702 162718 YBL031W S000000127 "ORF,_Verified" Cytoskeletal_protein_of_unknown_function;_overexpression_causes_growth_arrest YBL032W HEK2 KHD1 telomerase-dependent_telomere_maintenance* mRNA_binding cytoplasm* None None 2 160187 161332 YBL032W S000000128 "ORF,_Verified" RNA_binding_protein_with_similarity_to_hnRNP-K_that_localizes_to_the_cytoplasm_and_to_subtelomeric_DNA;_required_for_the_proper_localization_of_ASH1_mRNA;_involved_in_the_regulation_of_telomere_position_effect_and_telomere_length YBL033C RIB1 None riboflavin_biosynthesis cyclohydrolase_activity cytoplasm* None Up 2 159696 158659 YBL033C S000000129 "ORF,_Verified" GTP_cyclohydrolase_II;_catalyzes_the_first_step_of_the_riboflavin_biosynthesis_pathway YBL034C STU1 None microtubule_nucleation structural_constituent_of_cytoskeleton spindle_pole_body None None 2 158392 153851 YBL034C S000000130 "ORF,_Verified" Component_of_the_mitotic_spindle_that_binds_to_interpolar_microtubules_via_its_association_with_beta-tubulin_(Tub2p);_required_for_interpolar_microtubules_to_provide_an_outward_force_on_the_spindle_poles YBL035C POL12 None DNA_replication_initiation* alpha_DNA_polymerase_activity nucleus* G1 Up 2 153613 151496 YBL035C S000000131 "ORF,_Verified" "B_subunit_of_DNA_polymerase_alpha-primase_complex,_required_for_initiation_of_DNA_replication_during_mitotic_and_premeiotic_DNA_synthesis;_also_functions_in_telomere_capping_and_length_regulation" YBL036C None None amino_acid_metabolism alanine_racemase_activity* intracellular None None 2 151223 150450 YBL036C S000000132 "ORF,_Verified" "Single-domain_racemase,_possibly_non-specific_due_to_the_lack_of_the_second_domain,_which_presumably_determines_specificity;_GFP-fusion_protein_expression_is_induced_in_response_to_the_DNA-damaging_agent_MMS" YBL038W MRPL16 None protein_biosynthesis structural_constituent_of_ribosome* mitochondrial_large_ribosomal_subunit None None 2 146190 146888 YBL038W S000000134 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YBL040C ERD2 None protein_retention_in_ER HDEL_sequence_binding integral_to_endoplasmic_reticulum_membrane None None 2 142871 142115 YBL040C S000000136 "ORF,_Verified" "HDEL_receptor,_an_integral_membrane_protein_that_binds_to_the_HDEL_motif_in_proteins_destined_for_retention_in_the_endoplasmic_reticulum;_has_a_role_in_maintenance_of_normal_levels_of_ER-resident_proteins" YBL041W PRE7 PRS3 ubiquitin-dependent_protein_catabolism endopeptidase_activity "proteasome_core_complex,_beta-subunit_complex_(sensu_Eukaryota)" None None 2 141250 141975 YBL041W S000000137 "ORF,_Verified" Beta_6_subunit_of_the_20S_proteasome YBL043W ECM13 None cell_wall_organization_and_biogenesis molecular_function_unknown cellular_component_unknown None None 2 136691 137464 YBL043W S000000139 "ORF,_Verified" Non-essential_protein_of_unknown_function;_induced_by_treatment_with_8-methoxypsoralen_and_UVA_irradiation YBL044W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 136001 136369 YBL044W S000000140 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YBL044W_is_not_an_essential_protein YBL045C COR1 QCR1 aerobic_respiration ubiquinol-cytochrome-c_reductase_activity respiratory_chain_complex_III_(sensu_Eukaryota) None None 2 135519 134146 YBL045C S000000141 "ORF,_Verified" "Core_subunit_of_the_ubiquinol-cytochrome_c_reductase_complex_(bc1_complex),_which_is_a_component_of_the_mitochondrial_inner_membrane_electron_transport_chain" YBL046W PSY4 None biological_process_unknown molecular_function_unknown nucleus None None 2 132427 133752 YBL046W S000000142 "ORF,_Verified" Putative_regulatory_subunit_of_an_evolutionarily_conserved_protein_phosphatase_complex_containing_the_catalytic_subunit_Pph3p_and_a_third_subunit_Psy2p;_required_for_cisplatin_resistance;_GFP-fusion_protein_localizes_to_the_nucleus YBL047C EDE1 BUD15 endocytosis molecular_function_unknown bud_neck* None None 2 132043 127898 YBL047C S000000143 "ORF,_Verified" "Key_endocytic_protein_involved_in_a_network_of_interactions_with_other_endocytic_proteins,_binds_membranes_in_a_ubiquitin-dependent_manner,_may_also_bind_ubiquitinated_membrane-associated_proteins" YBL051C PIN4 MDT1 G2/M_transition_of_mitotic_cell_cycle* molecular_function_unknown cytoplasm None None 2 124762 122756 YBL051C S000000147 "ORF,_Verified" "Protein_involved_in_G2/M_phase_progression_and_response_to_DNA_damage,_interacts_with_Rad53p;_contains_an_RNA_recognition_motif,_a_nuclear_localization_signal,_and_several_SQ/TQ_cluster_domains;_hyperphosphorylated_in_response_to_DNA_damage" YBL052C SAS3 None chromatin_silencing_at_telomere* histone_acetyltransferase_activity* histone_acetyltransferase_complex* S/G2 None 2 121877 119382 YBL052C S000000148 "ORF,_Verified" "Histone_acetyltransferase_catalytic_subunit_of_NuA3_complex_that_acetylates_histone_H3,_involved_in_transcriptional_silencing;_homolog_of_the_mammalian_MOZ_proto-oncogene;_sas3_gcn5_double_mutation_confers_lethality" YBL056W PTC3 None protein_amino_acid_dephosphorylation* protein_phosphatase_type_2C_activity cytoplasm* None None 2 113765 115171 YBL056W S000000152 "ORF,_Verified" Type_2C_protein_phosphatase;_dephosphorylates_Hog1p_(see_also_Ptc2p)_to_limit_maximal_kinase_activity_induced_by_osmotic_stress;_dephosphorylates_T169_phosphorylated_Cdc28p_(see_also_Ptc2p);_role_in_DNA_checkpoint_inactivation YBL058W SHP1 UBX1 sporulation_(sensu_Fungi)* protein_phosphatase_type_1_regulator_activity cytoplasm* None Up 2 111439 112710 YBL058W S000000154 "ORF,_Verified" UBX_(ubiquitin_regulatory_X)_domain-containing_protein_that_regulates_Glc7p_phosphatase_activity_and_interacts_with_Cdc48p;_interacts_with_ubiquitylated_proteins_in_vivo_and_is_required_for_degradation_of_a_ubiquitylated_model_substrate YBL059C-A None None biological_process_unknown molecular_function_unknown cytoplasm* None None 2 110541 110127 YBL059C-A S000007488 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_contains_twin_Cx9C_motifs_that_can_form_coiled_coil-helix-coiled-coil_helix_fold;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus YBL059W None None biological_process_unknown molecular_function_unknown mitochondrion None None 2 110596 111246 YBL059W S000000155 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YBL061C SKT5 CSD4|CHS4|CAL2 response_to_osmotic_stress* enzyme_activator_activity bud_neck* M/G1 None 2 107408 105318 YBL061C S000000157 "ORF,_Verified" "Activator_of_Chs3p_(chitin_synthase_III),_recruits_Chs3p_to_the_bud_neck_via_interaction_with_Bni4p;_has_similarity_to_Shc1p,_which_activates_Chs3p_during_sporulation" YBL063W KIP1 CIN9 microtubule_nucleation* structural_constituent_of_cytoskeleton* spindle_pole_body* S None 2 101888 105223 YBL063W S000000159 "ORF,_Verified" Kinesin-related_motor_protein_required_for_mitotic_spindle_assembly_and_chromosome_segregation;_functionally_redundant_with_Cin8p YBL064C PRX1 None regulation_of_cell_redox_homeostasis thioredoxin_peroxidase_activity mitochondrion M/G1 Up 2 101158 100373 YBL064C S000000160 "ORF,_Verified" "Mitochondrial_peroxiredoxin_(1-Cys_Prx)_with_thioredoxin_peroxidase_activity,_has_a_role_in_reduction_of_hydroperoxides;_induced_during_respiratory_growth_and_under_conditions_of_oxidative_stress;_phosphorylated" YBL066C SEF1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 100117 96671 YBL066C S000000162 "ORF,_Verified" "Putative_transcription_factor,_has_homolog_in_Kluyveromyces_lactis" YBL067C UBP13 None biological_process_unknown ubiquitin-specific_protease_activity cellular_component_unknown None None 2 95884 93641 YBL067C S000000163 "ORF,_Verified" "Putative_ubiquitin_carboxyl-terminal_hydrolase,_ubiquitin-specific_protease_that_cleaves_ubiquitin-protein_fusions" YBL069W AST1 None protein_targeting_to_membrane molecular_function_unknown extrinsic_to_membrane None None 2 90739 92028 YBL069W S000000165 "ORF,_Verified" "Peripheral_membrane_protein_that_interacts_with_the_plasma_membrane_ATPase_Pma1p_and_has_a_role_in_its_targeting_to_the_plasma_membrane,_possibly_by_influencing_its_incorporation_into_lipid_rafts" YBL072C RPS8A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 2 89123 88521 YBL072C S000000168 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_identical_to_Rps8Bp_and_has_similarity_to_rat_S8_ribosomal_protein YBL074C AAR2 None assembly_of_spliceosomal_tri-snRNP molecular_function_unknown snRNP_U5 None None 2 87787 86720 YBL074C S000000170 "ORF,_Verified" "Component_of_the_U5_snRNP,_required_for_splicing_of_U3_precursors;_originally_described_as_a_splicing_factor_specifically_required_for_splicing_pre-mRNA_of_the_MATa1_cistron" YBL075C SSA3 YG106 response_to_stress* ATPase_activity cytosol None None 2 86446 84497 YBL075C S000000171 "ORF,_Verified" ATPase_involved_in_protein_folding_and_the_response_to_stress;_plays_a_role_in_SRP-dependent_cotranslational_protein-membrane_targeting_and_translocation;_member_of_the_heat_shock_protein_70_(HSP70)_family;_localized_to_the_cytoplasm YBL076C ILS1 None protein_biosynthesis isoleucine-tRNA_ligase_activity cytosol None None 2 84259 81041 YBL076C S000000172 "ORF,_Verified" "Cytoplasmic_isoleucine-tRNA_synthetase,_target_of_the_G1-specific_inhibitor_reveromycin_A" YBL079W NUP170 NLE3 mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 2 75256 79764 YBL079W S000000175 "ORF,_Verified" "Abundant_subunit_of_the_nuclear_pore_complex_(NPC),_required_for_proper_localization_of_specific_nucleoporins_within_the_NPC,_involved_in_nuclear_envelope_permeability_and_in_chromosome_segregation,_has_similarity_to_Nup157p" YBL080C PET112 None protein_biosynthesis* molecular_function_unknown mitochondrion None None 2 74692 73067 YBL080C S000000176 "ORF,_Verified" Protein_required_for_mitochondrial_translation;_mutation_is_functionally_complemented_by_a_Bacillus_subtilis_ortholog YBL081W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 71863 72969 YBL081W S000000177 "ORF,_Uncharacterized" Non-essential_protein_of_unknown_function;_null_mutation_results_in_a_decrease_in_plasma_membrane_electron_transport YBL082C ALG3 RHK1 protein_amino_acid_glycosylation* "alpha-1,3-mannosyltransferase_activity" endoplasmic_reticulum None None 2 71124 69748 YBL082C S000000178 "ORF,_Verified" "Dolichol-P-Man_dependent_alpha(1-3)_mannosyltransferase,_involved_in_the_synthesis_of_dolichol-linked_oligosaccharide_donor_for_N-linked_glycosylation_of_proteins" YBL085W BOI1 BOB1|GIN7 establishment_of_cell_polarity_(sensu_Fungi)* phospholipid_binding bud_neck* None None 2 63873 66815 YBL085W S000000181 "ORF,_Verified" "Protein_implicated_in_polar_growth,_functionally_redundant_with_Boi2p;_interacts_with_bud-emergence_protein_Bem1p;_contains_an_SH3_(src_homology_3)_domain_and_a_PH_(pleckstrin_homology)_domain" YBL087C RPL23A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 2 60735 59818 YBL087C S000000183 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_identical_to_Rpl23Bp_and_has_similarity_to_E._coli_L14_and_rat_L23_ribosomal_proteins" YBL088C TEL1 None response_to_DNA_damage_stimulus* protein_kinase_activity nucleus* None None 2 59379 51016 YBL088C S000000184 "ORF,_Verified" Protein_kinase_primarily_involved_in_telomere_length_regulation;_contributes_to_cell_cycle_checkpoint_control_in_response_to_DNA_damage;_functionally_redundant_with_Mec1p;_homolog_of_human_ataxia_telangiectasia_(ATM)_gene YBL089W AVT5 None transport transporter_activity cellular_component_unknown None None 2 49571 50950 YBL089W S000000185 "ORF,_Verified" "Putative_transporter,_member_of_a_family_of_seven_S._cerevisiae_genes_(AVT1-7)_related_to_vesicular_GABA-glycine_transporters" YBL090W MRP21 MRP50 protein_biosynthesis* structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 2 48822 49355 YBL090W S000000186 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit;_MRP21_exhibits_genetic_interactions_with_mutations_in_the_COX2_and_COX3_mRNA_5'-untranslated_leader_sequences YBL091C-A SCS22 None biological_process_unknown* molecular_function_unknown cellular_component_unknown None None 2 47177 46562 YBL091C-A S000007228 "ORF,_Verified" Protein_involved_in_regulation_of_phospholipid_metabolism;_homolog_of_Scs2p;_similar_to_D._melanogaster_inturned_protein YBL092W RPL32 None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 2 45975 46367 YBL092W S000000188 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_rat_L32_ribosomal_protein;_overexpression_disrupts_telomeric_silencing" YBL093C ROX3 MED19|SSN7|NUT3 transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_mediator_activity nucleus* None None 2 44915 44253 YBL093C S000000189 "ORF,_Verified" Subunit_of_the_RNA_polymerase_II_mediator_complex;_associates_with_core_polymerase_subunits_to_form_the_RNA_polymerase_II_holoenzyme YBL095W None None biological_process_unknown molecular_function_unknown mitochondrion None None 2 43274 44086 YBL095W S000000191 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YBL097W BRN1 None mitotic_sister_chromatid_segregation* molecular_function_unknown nucleus* None None 2 40828 43092 YBL097W S000000193 "ORF,_Verified" "Essential_protein_required_for_chromosome_condensation,_likely_to_function_as_an_intrinsic_component_of_the_condensation_machinery,_may_influence_multiple_aspects_of_chromosome_transmission_and_dynamics" YBL098W BNA4 None NAD_biosynthesis kynurenine_3-monooxygenase_activity mitochondrion G2/M None 2 39142 40524 YBL098W S000000194 "ORF,_Verified" "Kynurenine_3-mono_oxygenase,_required_for_the_de_novo_biosynthesis_of_NAD_from_tryptophan_via_kynurenine;_expression_regulated_by_Hst1p;_putative_therapeutic_target_for_Huntington_disease" YBL100W-A None TY2A_B|YBL101W-A None None None None None 2 29932 31248 YBL101W-A S000002148 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YBL102W SFT2 None Golgi_to_endosome_transport molecular_function_unknown Golgi_membrane None None 2 24098 24745 YBL102W S000000198 "ORF,_Verified" "Non-essential_tetra-spanning_membrane_protein_found_mostly_in_the_late_Golgi,_can_suppress_some_sed5_alleles;_may_be_part_of_the_transport_machinery,_but_precise_function_is_unknown;_similar_to_mammalian_syntaxin_5" YBL103C RTG3 None transcription_initiation_from_RNA_polymerase_II_promoter* specific_RNA_polymerase_II_transcription_factor_activity cytoplasm* None None 2 23535 22075 YBL103C S000000199 "ORF,_Verified" "Basic_helix-loop-helix-leucine_zipper_(bHLH/Zip)_transcription_factor_that_forms_a_complex_with_another_bHLH/Zip_protein,_Rtg1p,_to_activate_the_retrograde_(RTG)_and_TOR_pathways" YBL104C None YBL103C-A biological_process_unknown molecular_function_unknown cytoplasm None None 2 21293 18177 YBL104C S000000200 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_promoter_contains_multiple_GCN4_binding_sites" YBL106C SRO77 SNI2|SOP2 exocytosis* molecular_function_unknown plasma_membrane None None 2 13879 10847 YBL106C S000000202 "ORF,_Verified" Protein_with_roles_in_exocytosis_and_cation_homeostasis;_functions_in_docking_and_fusion_of_post-Golgi_vesicles_with_plasma_membrane;_homolog_of_Sro7p_and_Drosophila_lethal_giant_larvae_tumor_suppressor;_interacts_with_SNARE_protein_Sec9p YBL107C None None biological_process_unknown molecular_function_unknown cytoplasm None None 2 10551 9961 YBL107C S000000203 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YBL107C_is_not_an_essential_gene YBL111C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 2 5009 2907 YBL111C S000002151 "ORF,_Uncharacterized" Helicase-like_protein_encoded_within_the_telomeric_Y'_element YBL112C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 2 2899 2582 YBL112C S000002152 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YBL112C_is_contained_within_TEL02L YBL113C None None biological_process_unknown helicase_activity cellular_component_unknown G1 None 2 2658 280 YBL113C S000002153 "ORF,_Uncharacterized" Helicase-like_protein_encoded_within_the_telomeric_Y'_element YBR001C NTH2 None response_to_stress* "alpha,alpha-trehalase_activity" cytoplasm* None None 2 241285 238943 YBR001C S000000205 "ORF,_Verified" "Putative_neutral_trehalase,_required_for_thermotolerance_and_may_mediate_resistance_to_other_cellular_stresses" YBR003W COQ1 None ubiquinone_metabolism trans-hexaprenyltranstransferase_activity mitochondrion None None 2 242811 244232 YBR003W S000000207 "ORF,_Verified" "Hexaprenyl_pyrophosphate_synthetase,_catalyzes_the_first_step_in_ubiquinone_(coenzyme_Q)_biosynthesis" YBR004C GPI18 FMP44 GPI_anchor_biosynthesis mannosyltransferase_activity endoplasmic_reticulum None None 2 245669 244368 YBR004C S000000208 "ORF,_Verified" "Functional_ortholog_of_human_PIG-V,_which_is_a_mannosyltransferase_that_transfers_the_second_mannose_in_glycosylphosphatidylinositol_biosynthesis;_the_authentic,_non-tagged_protein_was_localized_to_mitochondria" YBR005W RCR1 SSH6 cell_wall_organization_and_biogenesis molecular_function_unknown integral_to_endoplasmic_reticulum_membrane None None 2 245908 246549 YBR005W S000000209 "ORF,_Verified" "Protein_of_the_ER_membrane_involved_in_cell_wall_chitin_deposition;_may_function_in_the_endosomal-vacuolar_trafficking_pathway,_helping_determine_whether_plasma_membrane_proteins_are_degraded_or_routed_to_the_plasma_membrane" YBR006W UGA2 UGA5 response_to_oxidative_stress* succinate-semialdehyde_dehydrogenase_[NAD(P)+]_activity cytoplasm None Up 2 247012 248505 YBR006W S000000210 "ORF,_Verified" Succinate_semialdehyde_dehydrogenase_involved_in_the_utilization_of_gamma-aminobutyrate_(GABA)_as_a_nitrogen_source;_part_of_the_4-aminobutyrate_and_glutamate_degradation_pathways;_localized_to_the_cytoplasm YBR008C FLR1 None response_to_toxin multidrug_transporter_activity integral_to_plasma_membrane S Up 2 254210 252564 YBR008C S000000212 "ORF,_Verified" "Plasma_membrane_multidrug_transporter_of_the_major_facilitator_superfamily,_involved_in_efflux_of_fluconazole,_diazaborine,_benomyl,_methotrexate,_and_other_drugs" YBR009C HHF1 None chromatin_assembly_or_disassembly DNA_binding nuclear_nucleosome S None 2 255682 255371 YBR009C S000000213 "ORF,_Verified" "Histone_H4,_core_histone_protein_required_for_chromatin_assembly_and_chromosome_function;_one_of_two_identical_histone_proteins_(see_also_HHF2);_contributes_to_telomeric_silencing;_N-terminal_domain_involved_in_maintaining_genomic_integrity" YBR010W HHT1 SIN2|BUR5 chromatin_assembly_or_disassembly DNA_binding nucleus* S None 2 256329 256739 YBR010W S000000214 "ORF,_Verified" "Histone_H3,_core_histone_protein_required_for_chromatin_assembly,_part_of_heterochromatin-mediated_telomeric_and_HM_silencing;_one_of_two_identical_histone_H3_proteins_(see_HHT2);_regulated_by_acetylation,_methylation,_and_phosphorylation" YBR011C IPP1 PPA1 phosphate_metabolism inorganic_diphosphatase_activity cytosol None None 2 257973 257110 YBR011C S000000215 "ORF,_Verified" "Cytoplasmic_inorganic_pyrophosphatase_(PPase),_catalyzes_the_rapid_exchange_of_oxygens_from_Pi_with_water,_highly_expressed_and_essential_for_viability,_active-site_residues_show_identity_to_those_from_E._coli_PPase" YBR012W-A None None None None None None None 2 259867 261189 YBR012W-A S000002154 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YBR012W-B None None None None None None None 2 259867 265138 YBR012W-B S000002155 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YBR013C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 265879 265490 YBR013C S000000217 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_haploid_deletion_mutant_exhibits_synthetic_phenotype_with_alpha-synuclein" YBR014C GRX7 None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi)* None None 2 267336 266725 YBR014C S000000218 "ORF,_Verified" Cis-golgi_localized_monothiol_glutaredoxin;_more_similar_in_activity_to_dithiol_than_other_monothiol_glutaredoxins;_involved_in_the_oxidative_stress_response;_does_not_bind_metal_ions;_functional_overlap_with_GRX6 YBR015C MNN2 LDB8|CRV4|TTP1 protein_amino_acid_glycosylation "alpha-1,2-mannosyltransferase_activity" Golgi_apparatus None None 2 269503 267710 YBR015C S000000219 "ORF,_Verified" "Alpha-1,2-mannosyltransferase,_responsible_for_addition_of_the_first_alpha-1,2-linked_mannose_to_form_the_branches_on_the_mannan_backbone_of_oligosaccharides,_localizes_to_an_early_Golgi_compartment" YBR016W None None response_to_desiccation molecular_function_unknown plasma_membrane None None 2 270247 270633 YBR016W S000000220 "ORF,_Uncharacterized" "Plasma_membrane_protein_of_unknown_function;_has_similarity_to_hydrophilins,_which_are_hydrophilic,_glycine-rich_proteins_involved_in_the_adaptive_response_to_hyperosmotic_conditions" YBR017C KAP104 None protein_import_into_nucleus* nuclear_localization_sequence_binding cytosol None None 2 273703 270947 YBR017C S000000221 "ORF,_Verified" "Transportin,_cytosolic_karyopherin_beta_2_involved_in_delivery_of_heterogeneous_nuclear_ribonucleoproteins_to_the_nucleoplasm,_binds_rg-nuclear_localization_signals_on_Nab2p_and_Hrp1p,_plays_a_role_in_cell-cycle_progression" YBR019C GAL10 None galactose_metabolism UDP-glucose_4-epimerase_activity cellular_component_unknown None None 2 278352 276253 YBR019C S000000223 "ORF,_Verified" "UDP-glucose-4-epimerase,_catalyzes_the_interconversion_of_UDP-galactose_and_UDP-D-glucose_in_galactose_metabolism;_also_catalyzes_the_conversion_of_alpha-D-glucose_or_alpha-D-galactose_to_their_beta-anomers" YBR021W FUR4 None uracil_transport uracil_permease_activity plasma_membrane* None None 2 281443 283344 YBR021W S000000225 "ORF,_Verified" "Uracil_permease,_localized_to_the_plasma_membrane;_expression_is_tightly_regulated_by_uracil_levels_and_environmental_cues" YBR025C OLA1 None biological_process_unknown molecular_function_unknown cytoplasm None None 2 291865 290681 YBR025C S000000229 "ORF,_Verified" P-loop_ATPase_with_similarity_to_human_OLA1_and_bacterial_YchF;_identified_as_specifically_interacting_with_the_proteasome;_protein_levels_are_induced_by_hydrogen_peroxide YBR026C ETR1 MRF1'|MRF1 aerobic_respiration* enoyl-[acyl-carrier_protein]_reductase_activity mitochondrion None None 2 294019 292877 YBR026C S000000230 "ORF,_Verified" "2-enoyl_thioester_reductase,_member_of_the_medium_chain_dehydrogenase/reductase_family;_localized_to_in_mitochondria,_where_it_has_a_probable_role_in_fatty_acid_synthesis" YBR028C None None biological_process_unknown protein_kinase_activity cytoplasm None None 2 296002 294425 YBR028C S000000232 "ORF,_Uncharacterized" "Putative_protein_kinase,_possible_substrate_of_cAMP-dependent_protein_kinase_(PKA)" YBR029C CDS1 CDG1 phosphatidylglycerol_biosynthesis* phosphatidate_cytidylyltransferase_activity mitochondrion* None None 2 297742 296369 YBR029C S000000233 "ORF,_Verified" "Phosphatidate_cytidylyltransferase_(CDP-diglyceride_synthetase);_an_enzyme_that_catalyzes_that_conversion_of_CTP_+_phosphate_into_diphosphate_+_CDP-diaclglyerol,_a_critical_step_in_the_synthesis_of_all_major_yeast_phospholipids" YBR030W None None phospholipid_metabolism molecular_function_unknown nucleus None None 2 298292 299950 YBR030W S000000234 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_predicted_protein_contains_a_SET_domain_(S-adenosyl-L-methionine-binding_fold) YBR031W RPL4A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 2 300166 301254 YBR031W S000000235 "ORF,_Verified" "N-terminally_acetylated_protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl4Bp_and_has_similarity_to_E._coli_L4_and_rat_L4_ribosomal_proteins" YBR033W EDS1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 301944 304703 YBR033W S000000237 "ORF,_Uncharacterized" Putative_zinc_cluster_protein;_YBR033W_is_not_an_essential_gene YBR034C HMT1 RMT1|ODP1|HCP1 mRNA_export_from_nucleus* protein-arginine_N-methyltransferase_activity nucleus None None 2 305976 304930 YBR034C S000000238 "ORF,_Verified" "Nuclear_SAM-dependent_mono-_and_asymmetric_arginine_dimethylating_methyltransferase_that_modifies_hnRNPs,_including_Npl3p_and_Hrp1p,_thus_facilitating_nuclear_export_of_these_proteins;_required_for_viability_of_npl3_mutants" YBR035C PDX3 None fatty_acid_metabolism pyridoxamine-phosphate_oxidase_activity cellular_component_unknown None None 2 306955 306269 YBR035C S000000239 "ORF,_Verified" "Pyridoxine_(pyridoxamine)_phosphate_oxidase,_has_homologs_in_E._coli_and_Myxococcus_xanthus;_transcription_is_under_the_general_control_of_nitrogen_metabolism" YBR036C CSG2 CLS2 calcium_ion_homeostasis* enzyme_regulator_activity integral_to_endoplasmic_reticulum_membrane None None 2 310313 309081 YBR036C S000000240 "ORF,_Verified" "Endoplasmic_reticulum_membrane_protein,_required_for_mannosylation_of_inositolphosphorylceramide_and_for_growth_at_high_calcium_concentrations" YBR037C SCO1 PET161 protein_complex_assembly* thioredoxin_peroxidase_activity* mitochondrial_inner_membrane None None 2 311451 310564 YBR037C S000000241 "ORF,_Verified" "Copper-binding_protein_of_the_mitochondrial_inner_membrane,_required_for_cytochrome_c_oxidase_activity_and_respiration;_may_function_to_deliver_copper_to_cytochrome_c_oxidase;_has_similarity_to_thioredoxins" YBR038W CHS2 None cytokinesis chitin_synthase_activity bud_neck G2/M None 2 311897 314788 YBR038W S000000242 "ORF,_Verified" "Chitin_synthase_II,_requires_activation_from_zymogenic_form_in_order_to_catalyze_the_transfer_of_N-acetylglucosamine_(GlcNAc)_to_chitin;_required_for_the_synthesis_of_chitin_in_the_primary_septum_during_cytokinesis" YBR039W ATP3 None ATP_synthesis_coupled_proton_transport "hydrogen-transporting_ATP_synthase_activity,_rotational_mechanism" "proton-transporting_ATP_synthase,_central_stalk_(sensu_Eukaryota)" None None 2 315575 316510 YBR039W S000000243 "ORF,_Verified" "Gamma_subunit_of_the_F1_sector_of_mitochondrial_F1F0_ATP_synthase,_which_is_a_large,_evolutionarily_conserved_enzyme_complex_required_for_ATP_synthesis" YBR044C TCM62 None protein_complex_assembly unfolded_protein_binding mitochondrial_inner_membrane None None 2 326058 324337 YBR044C S000000248 "ORF,_Verified" Protein_involved_in_the_assembly_of_the_mitochondrial_succinate_dehydrogenase_complex;_putative_chaperone YBR045C GIP1 None spore_wall_assembly_(sensu_Fungi) protein_phosphatase_type_1_regulator_activity* prospore_membrane* None None 2 330090 328369 YBR045C S000000249 "ORF,_Verified" "Meiosis-specific_regulatory_subunit_of_the_Glc7p_protein_phosphatase,_regulates_spore_wall_formation_and_septin_organization,_required_for_expression_of_some_late_meiotic_genes_and_for_normal_localization_of_Glc7p" YBR047W None None biological_process_unknown molecular_function_unknown mitochondrion None Up 2 331831 332358 YBR047W S000000251 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YBR048W RPS11B None protein_biosynthesis* structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None Down 2 332829 333810 YBR048W S000000252 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_identical_to_Rps11Ap_and_has_similarity_to_E._coli_S17_and_rat_S11_ribosomal_proteins YBR049C REB1 GRF2 regulation_of_transcription_from_RNA_polymerase_II_promoter* RNA_polymerase_II_transcription_factor_activity* nucleus None None 2 336816 334384 YBR049C S000000253 "ORF,_Verified" RNA_polymerase_I_enhancer_binding_protein;_DNA_binding_protein_which_binds_to_genes_transcribed_by_both_RNA_polymerase_I_and_RNA_polymerase_II;_required_for_termination_of_RNA_polymerase_I_transcription YBR050C REG2 None negative_regulation_of_transcription_from_RNA_polymerase_II_promoter protein_phosphatase_type_1_regulator_activity protein_phosphatase_type_1_complex None None 2 338197 337181 YBR050C S000000254 "ORF,_Verified" "Regulatory_subunit_of_the_Glc7p_type-1_protein_phosphatase;_involved_with_Reg1p,_Glc7p,_and_Snf1p_in_regulation_of_glucose-repressible_genes,_also_involved_in_glucose-induced_proteolysis_of_maltose_permease" YBR052C RFS1 None biological_process_unknown molecular_function_unknown cytoplasm None None 2 339350 338718 YBR052C S000000256 "ORF,_Verified" Protein_of_unknown_function;_member_of_a_flavodoxin-like_fold_protein_family_that_includes_Pst2p_and_Ycp4p;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern YBR053C None None biological_process_unknown molecular_function_unknown cellular_component_unknown M/G1 Up 2 340749 339673 YBR053C S000000257 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_induced_by_cell_wall_perturbation YBR054W YRO2 None biological_process_unknown molecular_function_unknown mitochondrion* G2/M None 2 343099 344133 YBR054W S000000258 "ORF,_Verified" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_a_phosphorylated_state_in_highly_purified_mitochondria_in_high-throughput_studies;_transcriptionally_regulated_by_Haa1p" YBR056W None None biological_process_unknown molecular_function_unknown cytoplasm None None 2 347877 349382 YBR056W S000000260 "ORF,_Uncharacterized" Putative_cytoplasmic_protein_of_unknown_function YBR057C MUM2 SPOT8 premeiotic_DNA_synthesis molecular_function_unknown cytoplasm None None 2 353291 352191 YBR057C S000000261 "ORF,_Verified" "Cytoplasmic_protein_essential_for_meiotic_DNA_replication_and_sporulation;_interacts_with_Orc2p,_which_is_a_component_of_the_origin_recognition_complex" YBR059C AKL1 None actin_cytoskeleton_organization_and_biogenesis* protein_kinase_activity cytoplasm* None None 2 360185 356859 YBR059C S000000263 "ORF,_Verified" "Ser-Thr_protein_kinase,_member_(with_Ark1p_and_Prk1p)_of_the_Ark_kinase_family;_involved_in_endocytosis_and_actin_cytoskeleton_organization" YBR060C ORC2 SIR5|RRR1 DNA_replication_initiation* DNA_replication_origin_binding pre-replicative_complex* None None 2 362512 360650 YBR060C S000000264 "ORF,_Verified" "Subunit_of_the_origin_recognition_complex,_which_directs_DNA_replication_by_binding_to_replication_origins_and_is_also_involved_in_transcriptional_silencing;_phosphorylated_by_Cdc28p" YBR061C TRM7 None protein_biosynthesis* tRNA_methyltransferase_activity cytoplasm None None 2 365717 364785 YBR061C S000000265 "ORF,_Verified" "2'-O-ribose_methyltransferase,_methylates_the_2'-O-ribose_of_nucleotides_at_positions_32_and_34_of_the_tRNA_anticodon_loop" YBR062C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 366598 365974 YBR062C S000000266 "ORF,_Uncharacterized" Hypothetical_protein YBR063C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 368182 366968 YBR063C S000000267 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YBR063C_is_not_an_essential_gene YBR065C ECM2 SLT11 cell_wall_organization_and_biogenesis* molecular_function_unknown nucleus None None 2 369676 368582 YBR065C S000000269 "ORF,_Verified" "Pre-mRNA_splicing_factor,_facilitates_the_cooperative_formation_of_U2/U6_helix_II_in_association_with_stem_II_in_the_spliceosome,_function_may_be_regulated_by_Slu7p" YBR067C TIP1 None cell_wall_organization_and_biogenesis structural_constituent_of_cell_wall* cell_wall_(sensu_Fungi) G1 None 2 372732 372100 YBR067C S000000271 "ORF,_Verified" Major_cell_wall_mannoprotein_with_possible_lipase_activity;_transcription_is_induced_by_heat-_and_cold-shock;_member_of_the_Srp1p/Tip1p_family_of_serine-alanine-rich_proteins YBR068C BAP2 None amino_acid_transport amino_acid_transporter_activity plasma_membrane None None 2 375687 373858 YBR068C S000000272 "ORF,_Verified" "High-affinity_leucine_permease,_functions_as_a_branched-chain_amino_acid_permease_involved_in_the_uptake_of_leucine,_isoleucine_and_valine;_contains_12_predicted_transmembrane_domains" YBR069C TAT1 VAP1|TAP1 amino_acid_transport amino_acid_transporter_activity plasma_membrane G2/M None 2 378430 376571 YBR069C S000000273 "ORF,_Verified" "Amino_acid_transport_protein_for_valine,_leucine,_isoleucine,_and_tyrosine,_low-affinity_tryptophan_and_histidine_transporter;_overexpression_confers_FK506_and_FTY720_resistance" YBR070C ALG14 None dolichol-linked_oligosaccharide_biosynthesis N-acetylglucosaminyldiphosphodolichol_N-acetylglucosaminyltransferase_activity* membrane_fraction* G1 None 2 379931 379218 YBR070C S000000274 "ORF,_Verified" Component_of_UDP-GlcNAc_transferase_required_for_the_second_step_of_dolichyl-linked_oligosaccharide_synthesis;_anchors_the_catalytic_subunit_Alg13p_to_the_ER_membrane;_similar_to_bacterial_and_human_glycosyltransferases YBR071W None None biological_process_unknown molecular_function_unknown cytoplasm G1 None 2 380408 381043 YBR071W S000000275 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_(GFP)-fusion_and_epitope-tagged_proteins_localize_to_the_cytoplasm;_mRNA_expression_may_be_regulated_by_the_cell_cycle_and/or_cell_wall_stress YBR074W None YBR075W proteolysis metalloendopeptidase_activity cellular_component_unknown None None 2 386281 389211 YBR074W S000000278 "ORF,_Uncharacterized" Putative_metalloprotease YBR076W ECM8 None cell_wall_organization_and_biogenesis molecular_function_unknown cellular_component_unknown None None 2 390369 391388 YBR076W S000000280 "ORF,_Verified" Non-essential_protein_of_unknown_function YBR077C SLM4 GSE1|NIR1|EGO3 signal_transduction* "phosphatidylinositol-3,4-bisphosphate_binding" cytoplasm* None None 2 392287 391799 YBR077C S000000281 "ORF,_Verified" "Component_of_the_EGO_complex,_which_is_involved_in_the_regulation_of_microautophagy,_and_of_the_GSE_complex,_which_is_required_for_proper_sorting_of_amino_acid_permease_Gap1p;_gene_exhibits_synthetic_genetic_interaction_with_MSS4" YBR078W ECM33 None cell_wall_organization_and_biogenesis molecular_function_unknown mitochondrion* None None 2 393118 394854 YBR078W S000000282 "ORF,_Verified" "GPI-anchored_protein_of_unknown_function,_has_a_possible_role_in_apical_bud_growth;_GPI-anchoring_on_the_plasma_membrane_crucial_to_function;_phosphorylated_in_mitochondria;_similar_to_Sps2p_and_Pst1p" YBR079C RPG1 TIF32 translational_initiation translation_initiation_factor_activity cytoplasm* None None 2 398271 395377 YBR079C S000000283 "ORF,_Verified" "Subunit_of_the_core_complex_of_translation_initiation_factor_3(eIF3),_essential_for_translation;_part_of_a_subcomplex_(Prt1p-Rpg1p-Nip1p)_that_stimulates_binding_of_mRNA_and_tRNA(i)Met_to_ribosomes" YBR081C SPT7 GIT2 protein_complex_assembly* structural_molecule_activity mitochondrion* None None 2 405245 401247 YBR081C S000000285 "ORF,_Verified" "Subunit_of_the_SAGA_transcriptional_regulatory_complex,_involved_in_proper_assembly_of_the_complex;_also_present_as_a_C-terminally_truncated_form_in_the_SLIK/SALSA_transcriptional_regulatory_complex" YBR082C UBC4 None response_to_stress* ubiquitin_conjugating_enzyme_activity proteasome_complex_(sensu_Eukaryota) None None 2 407163 406622 YBR082C S000000286 "ORF,_Verified" "Ubiquitin-conjugating_enzyme_(E2),_mediates_degradation_of_short-lived_and_abnormal_proteins;_interacts_with_E3-CaM_in_ubiquitinating_calmodulin;_interacts_with_many_SCF_ubiquitin_protein_ligases;_component_of_the_cellular_stress_response" YBR083W TEC1 ROC1 pseudohyphal_growth* specific_RNA_polymerase_II_transcription_factor_activity nucleus M/G1 None 2 409163 410623 YBR083W S000000287 "ORF,_Verified" "Transcription_factor_required_for_full_Ty1_epxression,_Ty1-mediated_gene_activation,_and_haploid_invasive_and_diploid_pseudohyphal_growth;_TEA/ATTS_DNA-binding_domain_family_member" YBR084C-A RPL19A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 2 415255 414180 YBR084C-A S000002156 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl19Bp_and_has_similarity_to_rat_L19_ribosomal_protein;_rpl19a_and_rpl19b_single_null_mutations_result_in_slow_growth,_while_the_double_null_mutation_is_lethal" YBR085W AAC3 ANC3 anaerobic_respiration ATP:ADP_antiporter_activity mitochondrial_inner_membrane None None 2 415977 416900 YBR085W S000000289 "ORF,_Verified" "Mitochondrial_inner_membrane_ADP/ATP_translocator,_exchanges_cytosolic_ADP_for_mitochondrially_synthesized_ATP;_expressed_under_anaerobic_conditions;_similar_to_Pet9p_and_Aac1p;_has_roles_in_maintenance_of_viability_and_in_respiration" YBR086C IST2 None response_to_osmotic_stress molecular_function_unknown plasma_membrane* G2/M None 2 423035 420195 YBR086C S000000290 "ORF,_Verified" "Plasma_membrane_protein_that_may_be_involved_in_osmotolerance,_localizes_to_the_mother_cell_in_small-budded_cells_and_to_the_bud_in_medium-_and_large-budded_cells;_mRNA_is_transported_to_the_bud_tip_by_an_actomyosin-driven_process" YBR087W RFC5 None mismatch_repair* DNA_clamp_loader_activity DNA_replication_factor_C_complex G1 None 2 423759 424823 YBR087W S000000291 "ORF,_Verified" "Subunit_of_heteropentameric_Replication_factor_C_(RF-C),_which_is_a_DNA_binding_protein_and_ATPase_that_acts_as_a_clamp_loader_of_the_proliferating_cell_nuclear_antigen_(PCNA)_processivity_factor_for_DNA_polymerases_delta_and_epsilon" YBR088C POL30 None nucleotide-excision_repair* DNA_polymerase_processivity_factor_activity nucleus* G1 None 2 425760 424984 YBR088C S000000292 "ORF,_Verified" "Proliferating_cell_nuclear_antigen_(PCNA),_functions_as_the_sliding_clamp_for_DNA_polymerase_delta;_may_function_as_a_docking_site_for_other_proteins_required_for_mitotic_and_meiotic_chromosomal_DNA_replication_and_for_DNA_repair" YBR090C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 2 427052 426327 YBR090C S000000294 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus YBR091C MRS5 TIM12 protein_import_into_mitochondrial_inner_membrane protein_transporter_activity mitochondrial_intermembrane_space* None None 2 427478 427149 YBR091C S000000295 "ORF,_Verified" "Essential_protein_of_the_inner_mitochondrial_membrane,_peripherally_localized;_component_of_the_TIM22_complex,_which_is_a_twin-pore_translocase_that_mediates_insertion_of_numerous_multispanning_inner_membrane_proteins" YBR092C PHO3 phoC phosphate_metabolism* acid_phosphatase_activity periplasmic_space_(sensu_Fungi) G2/M Down 2 429095 427692 YBR092C S000000296 "ORF,_Verified" "Constitutively_expressed_acid_phosphatase_similar_to_Pho5p;_brought_to_the_cell_surface_by_transport_vesicles;_hydrolyzes_thiamin_phosphates_in_the_periplasmic_space,_increasing_cellular_thiamin_uptake;_expression_is_repressed_by_thiamin" YBR093C PHO5 phoE phosphate_metabolism* acid_phosphatase_activity* cell_wall_(sensu_Fungi)* G2/M None 2 430945 429542 YBR093C S000000297 "ORF,_Verified" Repressible_acid_phosphatase_(1_of_3)_that_also_mediates_extracellular_nucleotide-derived_phosphate_hydrolysis;_secretory_pathway_derived_cell_surface_glycoprotein;_induced_by_phosphate_starvation_and_coordinately_regulated_by_PHO4_and_PHO2 YBR095C RXT2 RAF60 invasive_growth_(sensu_Saccharomyces)* molecular_function_unknown nucleus None None 2 435692 434400 YBR095C S000000299 "ORF,_Verified" Subunit_of_the_histone_deacetylase_Rpd3L_complex;_possibly_involved_in_cell_fusion_and_invasive_growth YBR096W None None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 2 436015 436707 YBR096W S000000300 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_ER YBR098W MMS4 YBR100W|SLX2 DNA_repair* transcription_coactivator_activity* nucleus None None 2 441509 443584 YBR100W S000000302 "ORF,_Verified" Subunit_of_the_structure-specific_Mms4p-Mus81p_endonuclease_that_cleaves_branched_DNA;_involved_in_recombination_and_DNA_repair YBR101C FES1 None protein_biosynthesis adenyl-nucleotide_exchange_factor_activity cytosol* None None 2 444687 443815 YBR101C S000000305 "ORF,_Verified" "Hsp70_(Ssa1p)_nucleotide_exchange_factor,_cytosolic_homolog_of_Sil1p,_which_is_the_nucleotide_exchange_factor_for_BiP_(Kar2p)_in_the_endoplasmic_reticulum" YBR103W SIF2 EMB1 chromatin_silencing_at_telomere* transcription_corepressor_activity* nucleus* None None 2 447703 449310 YBR103W S000000307 "ORF,_Verified" "WD40_repeat-containing_subunit_of_the_Set3C_histone_deacetylase_complex,_which_represses_early/middle_sporulation_genes;_antagonizes_telomeric_silencing;_binds_specifically_to_the_Sir4p_N-terminus" YBR104W YMC2 None transport transporter_activity mitochondrial_inner_membrane None None 2 449661 450650 YBR104W S000000308 "ORF,_Verified" "Mitochondrial_protein,_putative_inner_membrane_transporter_with_a_role_in_oleate_metabolism_and_glutamate_biosynthesis;_member_of_the_mitochondrial_carrier_(MCF)_family;_has_similarity_with_Ymc1p" YBR106W PHO88 None phosphate_transport phosphate_transporter_activity mitochondrion* None None 2 452652 453218 YBR106W S000000310 "ORF,_Verified" "Probable_membrane_protein,_involved_in_phosphate_transport;_pho88_pho86_double_null_mutant_exhibits_enhanced_synthesis_of_repressible_acid_phosphatase_at_high_inorganic_phosphate_concentrations" YBR107C IML3 MCM19 sporulation_(sensu_Fungi)* molecular_function_unknown outer_kinetochore_of_condensed_nuclear_chromosome None None 2 454524 453787 YBR107C S000000311 "ORF,_Verified" "Protein_with_a_role_in_kinetochore_function,_localizes_to_the_outer_kinetochore_in_a_Ctf19p-dependent_manner,_interacts_with_Chl4p_and_Ctf19p" YBR109C CMD1 CaM endocytosis* protein_binding* cytoplasm* None None 2 458356 457913 YBR109C S000000313 "ORF,_Verified" "Calmodulin;_Ca++_binding_protein_that_regulates_Ca++_independent_processes_(mitosis,_bud_growth,_actin_organization,_endocytosis,_etc.)_and_Ca++_dependent_processes_(stress-activated_pathways),_targets_include_Nuf1p,_Myo2p_and_calcineurin" YBR112C CYC8 SSN6|CRT8 chromatin_remodeling* transcription_coactivator_activity* nucleus None None 2 465764 462864 YBR112C S000000316 "ORF,_Verified" "General_transcriptional_co-repressor,_acts_together_with_Tup1p;_also_acts_as_part_of_a_transcriptional_co-activator_complex_that_recruits_the_SWI/SNF_and_SAGA_complexes_to_promoters" YBR115C LYS2 None lysine_biosynthesis_via_aminoadipic_acid L-aminoadipate-semialdehyde_dehydrogenase_activity cytoplasm None None 2 473920 469742 YBR115C S000000319 "ORF,_Verified" "Alpha_aminoadipate_reductase,_catalyzes_the_reduction_of_alpha-aminoadipate_to_alpha-aminoadipate_6-semialdehyde,_which_is_the_fifth_step_in_biosynthesis_of_lysine;_activation_requires_posttranslational_phosphopantetheinylation_by_Lys5p" YBR117C TKL2 None pentose-phosphate_shunt transketolase_activity cytoplasm* None None 2 476431 474386 YBR117C S000000321 "ORF,_Verified" "Transketolase,_similar_to_Tkl1p;_catalyzes_conversion_of_xylulose-5-phosphate_and_ribose-5-phosphate_to_sedoheptulose-7-phosphate_and_glyceraldehyde-3-phosphate_in_the_pentose_phosphate_pathway;_needed_for_synthesis_of_aromatic_amino_acids" YBR119W MUD1 None "nuclear_mRNA_splicing,_via_spliceosome" RNA_binding snRNP_U1 None None 2 479332 480317 YBR119W S000000323 "ORF,_Verified" "U1_snRNP_A_protein,_homolog_of_human_U1-A;_involved_in_nuclear_mRNA_splicing" YBR121C GRS1 None glycyl-tRNA_aminoacylation* glycine-tRNA_ligase_activity cytoplasm* None None 2 483361 481358 YBR121C S000000325 "ORF,_Verified" Cytoplasmic_and_mitochondrial_glycyl-tRNA_synthase_that_ligates_glycine_to_the_cognate_anticodon_bearing_tRNA;_transcription_termination_factor_that_may_interact_with_the_3'-end_of_pre-mRNA_to_promote_3'-end_formation YBR122C MRPL36 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 2 484497 483964 YBR122C S000000326 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit;_overproduction_suppresses_mutations_in_the_COX2_leader_peptide-encoding_region YBR123C TFC1 None transcription_initiation_from_RNA_polymerase_III_promoter RNA_polymerase_III_transcription_factor_activity transcription_factor_TFIIIC_complex None None 2 486685 484736 YBR123C S000000327 "ORF,_Verified" One_of_six_subunits_of_the_RNA_polymerase_III_transcription_initiation_factor_complex_(TFIIIC);_part_of_the_TauA_globular_domain_of_TFIIIC_that_binds_DNA_at_the_BoxA_promoter_sites_of_tRNA_and_similar_genes;_human_homolog_is_TFIIIC-63 YBR125C PTC4 GCT1 biological_process_unknown protein_phosphatase_type_2C_activity cytoplasm None None 2 488374 487193 YBR125C S000000329 "ORF,_Verified" Cytoplasmic_type_2C_protein_phosphatase;_identified_as_a_high-copy_number_suppressor_of_the_synthetic_lethality_of_a_cnb1_mpk1_double_deletion;_overexpression_decreases_high-osmolarity_induced_Hog1p_phosphorylation_and_kinase_activity YBR126C TPS1 TSS1|GLC6|GGS1|FDP1|CIF1|BYP1 response_to_stress* "alpha,alpha-trehalose-phosphate_synthase_(UDP-forming)_activity" cytoplasm* None Up 2 490386 488899 YBR126C S000000330 "ORF,_Verified" "Synthase_subunit_of_trehalose-6-phosphate_synthase/phosphatase_complex,_which_synthesizes_the_storage_carbohydrate_trehalose;_also_found_in_a_monomeric_form;_expression_is_induced_by_the_stress_response_and_repressed_by_the_Ras-cAMP_pathway" YBR127C VMA2 ATPSV|VAT2 vacuolar_acidification "hydrogen-transporting_ATPase_activity,_rotational_mechanism" cytoplasm* None None 2 492816 491263 YBR127C S000000331 "ORF,_Verified" "Subunit_B_of_the_eight-subunit_V1_peripheral_membrane_domain_of_the_vacuolar_H+-ATPase_(V-ATPase),_an_electrogenic_proton_pump_found_throughout_the_endomembrane_system;_contains_nucleotide_binding_sites;_also_detected_in_the_cytoplasm" YBR129C OPY1 None conjugation_with_cellular_fusion molecular_function_unknown cytoplasm* None None 2 495333 494347 YBR129C S000000333 "ORF,_Verified" "Protein_of_unknown_function,_overproduction_blocks_cell_cycle_arrest_in_the_presence_of_mating_pheromone;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YBR131W CCZ1 CVT16 protein_targeting_to_vacuole* guanyl-nucleotide_exchange_factor_activity membrane* None None 2 497157 499271 YBR131W S000000335 "ORF,_Verified" "Protein_involved_in_vacuolar_assembly,_essential_for_autophagy_and_the_cytoplasm-to-vacuole_pathway" YBR132C AGP2 None response_to_osmotic_stress* amino_acid_transporter_activity* endoplasmic_reticulum_membrane* None None 2 501436 499646 YBR132C S000000336 "ORF,_Verified" "High_affinity_polyamine_permease,_preferentially_uses_spermidine_over_putrescine;_expression_is_down-regulated_by_osmotic_stress;_plasma_membrane_carnitine_transporter,_also_functions_as_a_low-affinity_amino_acid_permease" YBR133C HSL7 None regulation_of_progression_through_cell_cycle* protein-arginine_N-methyltransferase_activity bud_neck S/G2 None 2 504281 501798 YBR133C S000000337 "ORF,_Verified" "Protein_arginine_N-methyltransferase_that_exhibits_septin_and_Hsl1p-dependent_bud_neck_localization_and_periodic_Hsl1p-dependent_phosphorylation;_required_along_with_Hsl1p_for_bud_neck_recruitment,_phosphorylation,_and_degradation_of_Swe1p" YBR135W CKS1 None transcription* protein_kinase_activator_activity cytoplasm* None None 2 504848 505300 YBR135W S000000339 "ORF,_Verified" "Cyclin-dependent_protein_kinase_regulatory_subunit_and_adaptor;_modulates_proteolysis_of_M-phase_targets_through_interactions_with_the_proteasome;_role_in_transcriptional_regulation,_recruiting_proteasomal_subunits_to_target_gene_promoters" YBR136W MEC1 SAD3|ESR1 meiotic_recombination* protein_kinase_activity nucleus* None None 2 505662 512768 YBR136W S000000340 "ORF,_Verified" Genome_integrity_checkpoint_protein_and_PI_kinase_superfamily_member;_signal_transducer_required_for_cell_cycle_arrest_and_transcriptional_responses_prompted_by_damaged_or_unreplicated_DNA;_monitors_and_participates_in_meiotic_recombination YBR137W None None biological_process_unknown molecular_function_unknown cytoplasm None Up 2 513038 513577 YBR137W S000000341 "ORF,_Uncharacterized" Protein_of_unknown_function;_localized_to_the_cytoplasm;_binds_to_Replication_Protein_A_(RPA);_YBR137W_is_not_an_essential_gene YBR138C None HDR1 biological_process_unknown molecular_function_unknown cytoplasm G2/M None 2 515330 513756 YBR138C S000000342 "ORF,_Uncharacterized" "Cytoplasmic_protein_of_unknown_function,_potentially_phosphorylated_by_Cdc28p;_YBR138C_is_not_an_essential_gene" YBR139W None None biological_process_unknown carboxypeptidase_C_activity vacuole_(sensu_Fungi) G2/M Up 2 515658 517184 YBR139W S000000343 "ORF,_Verified" "Putative_serine_type_carboxypeptidase_with_a_role_in_phytochelatin_synthesis;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuole;_expression_induced_by_nitrogen_limitation_in_a_GLN3,_GAT1-independent_manner" YBR141C None None biological_process_unknown molecular_function_unknown nucleolus None None 2 528032 527019 YBR141C S000000345 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleolus;_YBR141C_is_not_an_essential_gene YBR142W MAK5 None rRNA_processing* ATP-dependent_RNA_helicase_activity nucleolus None None 2 528311 530632 YBR142W S000000346 "ORF,_Verified" "Essential_nucleolar_protein,_putative_DEAD-box_RNA_helicase_required_for_maintenance_of_M1_dsRNA_virus;_involved_in_biogenesis_of_large_(60S)_ribosomal_subunits" YBR145W ADH5 None alcohol_metabolism alcohol_dehydrogenase_activity cytoplasm* None Up 2 533756 534811 YBR145W S000000349 "ORF,_Verified" Alcohol_dehydrogenase_isoenzyme_V;_involved_in_ethanol_production YBR147W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None Up 2 536569 537459 YBR147W S000000351 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_null_mutant_displays_fluconazole_resistance_and_suppresses_cdc13-1_temperature_sensitivity" YBR148W YSW1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 537870 539699 YBR148W S000000352 "ORF,_Verified" Protein_expressed_specifically_in_spores YBR149W ARA1 None carbohydrate_metabolism aldo-keto_reductase_activity* cytosol None Up 2 539981 541015 YBR149W S000000353 "ORF,_Verified" "NADP+_dependent_arabinose_dehydrogenase,_involved_in_carbohydrate_metabolism;_purified_as_homodimer;_naturally_occurs_with_a_N-terminus_degradation_product" YBR150C TBS1 None biological_process_unknown molecular_function_unknown cytoplasm* None None 2 544487 541203 YBR150C S000000354 "ORF,_Verified" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YBR151W APD1 None biological_process_unknown molecular_function_unknown cytoplasm* None None 2 545022 545972 YBR151W S000000355 "ORF,_Verified" "Protein_of_unknown_function,_required_for_normal_localization_of_actin_patches_and_for_normal_tolerance_of_sodium_ions_and_hydrogen_peroxide;_localizes_to_both_cytoplasm_and_nucleus" YBR152W SPP381 None "nuclear_mRNA_splicing,_via_spliceosome*" protein_binding* U4/U6_x_U5_tri-snRNP_complex None None 2 546370 547245 YBR152W S000000356 "ORF,_Verified" "mRNA_splicing_factor,_component_of_U4/U6.U5_tri-snRNP;_interacts_genetically_and_physically_with_Prp38p" YBR153W RIB7 None riboflavin_biosynthesis diaminohydroxyphosphoribosylaminopyrimidine_deaminase_activity cellular_component_unknown None None 2 547454 548188 YBR153W S000000357 "ORF,_Verified" Diaminohydroxyphoshoribosylaminopyrimidine_deaminase;_catalyzes_the_second_step_of_the_riboflavin_biosynthesis_pathway YBR154C RPB5 None transcription_from_RNA_polymerase_II_promoter* DNA-directed_RNA_polymerase_activity DNA-directed_RNA_polymerase_III_complex* None None 2 549003 548356 YBR154C S000000358 "ORF,_Verified" "RNA_polymerase_subunit_ABC27,_common_to_RNA_polymerases_I,_II,_and_III;_contacts_DNA_and_affects_transactivation" YBR155W CNS1 None protein_folding unfolded_protein_binding cytoplasm None None 2 549765 550922 YBR155W S000000359 "ORF,_Verified" "TPR-containing_co-chaperone;_binds_both_Hsp82p_(Hsp90)_and_Ssa1p_(Hsp70)_and_stimulates_the_ATPase_activity_of_SSA1,_ts_mutants_reduce_Hsp82p_function_while_over_expression_suppresses_the_phenotypes_of_an_HSP82_ts_allele_and_a_cpr7_deletion" YBR156C SLI15 None protein_amino_acid_phosphorylation* protein_kinase_activator_activity spindle_microtubule* None None 2 553194 551098 YBR156C S000000360 "ORF,_Verified" "Subunit_of_the_Ipl1p-Sli15p-Bir1p_complex_that_regulates_kinetochore-microtubule_attachments,_activation_of_the_spindle_tension_checkpoint,_and_mitotic_spindle_disassembly;_regulates_the_activity_and_localization_of_the_Ipl1p_aurora_kinase" YBR157C ICS2 None biological_process_unknown molecular_function_unknown cellular_component_unknown M/G1 None 2 554304 553537 YBR157C S000000361 "ORF,_Verified" "Protein_of_unknown_function;_null_mutation_does_not_confer_any_obvious_defects_in_growth,_spore_germination,_viability,_or_carbohydrate_utilization" YBR158W AMN1 CST13|ICS4 negative_regulation_of_exit_from_mitosis* protein_binding cytoplasm* M/G1 None 2 556543 558192 YBR158W S000000362 "ORF,_Verified" "Protein_required_for_daughter_cell_separation,_multiple_mitotic_checkpoints,_and_chromosome_stability;_contains_12_degenerate_leucine-rich_repeat_motifs;_expression_is_induced_by_the_Mitotic_Exit_Network_(MEN)" YBR159W None None fatty_acid_elongation ketoreductase_activity endoplasmic_reticulum* None None 2 558679 559722 YBR159W S000000363 "ORF,_Verified" "Microsomal_beta-keto-reductase;_contains_oleate_response_element_(ORE)_sequence_in_the_promoter_region;_mutants_exhibit_reduced_VLCFA_synthesis,_accumulate_high_levels_of_dihydrosphingosine,_phytosphingosine_and_medium-chain_ceramides" YBR160W CDC28 SRM5|HSL5|CDK1 protein_amino_acid_phosphorylation* cyclin-dependent_protein_kinase_activity cytoplasm* None None 2 560072 560968 YBR160W S000000364 "ORF,_Verified" Catalytic_subunit_of_the_main_cell_cycle_cyclin-dependent_kinase_(CDK);_alternately_associates_with_G1_cyclins_(CLNs)_and_G2/M_cyclins_(CLBs)_which_direct_the_CDK_to_specific_substrates YBR161W CSH1 None sphingolipid_biosynthesis* mannosyltransferase_activity* vacuole_(sensu_Fungi) G1 None 2 561629 562759 YBR161W S000000365 "ORF,_Verified" "Probable_catalytic_subunit_of_a_mannosylinositol_phosphorylceramide_(MIPC)_synthase,_forms_a_complex_with_probable_regulatory_subunit_Csg2p;_function_in_sphingolipid_biosynthesis_is_overlapping_with_that_of_Sur1p" YBR162C TOS1 None biological_process_unknown molecular_function_unknown cell_wall_(sensu_Fungi)* None None 2 564565 563198 YBR162C S000000366 "ORF,_Verified" "Covalently-bound_cell_wall_protein_of_unknown_function;_identified_as_a_cell_cycle_regulated_SBF_target_gene;_deletion_mutants_are_highly_resistant_to_treatment_with_beta-1,3-glucanase;_has_sequence_similarity_to_YJL171C" YBR162W-A YSY6 None protein_secretion molecular_function_unknown endoplasmic_reticulum None None 2 565226 565423 YBR162W-A S000002158 "ORF,_Verified" Protein_whose_expression_suppresses_a_secretory_pathway_mutation_in_E._coli;_has_similarity_to_the_mammalian_RAMP4_protein_involved_in_secretion YBR163W DEM1 None biological_process_unknown molecular_function_unknown mitochondrion None None 2 565718 567475 YBR163W S000000367 "ORF,_Verified" Mitochondrial_protein_of_unknown_function;_null_mutant_has_defects_in_cell_morphology_and_in_response_to_air_drying;_may_be_regulated_by_the_transcription_factor_Ace2 YBR164C ARL1 DLP2 protein_targeting_to_vacuole* GTPase_activity Golgi_apparatus* None None 2 568421 567870 YBR164C S000000368 "ORF,_Verified" "Soluble_GTPase_with_a_role_in_regulation_of_membrane_traffic;_regulates_potassium_influx;_G_protein_of_the_Ras_superfamily,_similar_to_ADP-ribosylation_factor" YBR165W UBS1 None protein_export_from_nucleus* molecular_function_unknown nucleus None None 2 568847 569680 YBR165W S000000369 "ORF,_Verified" Ubiquitin-conjugating_enzyme_suppressor_that_functions_as_a_general_positive_regulator_of_Cdc34p_activity;_nuclear_protein_that_may_represent_a_link_between_nucleocytoplasmic_transport_and_ubiquitin_ligase_activity YBR166C TYR1 None tyrosine_metabolism prephenate_dehydrogenase_activity cytoplasm None None 2 571195 569837 YBR166C S000000370 "ORF,_Verified" "Prephenate_dehydrogenase_involved_in_tyrosine_biosynthesis,_expression_is_dependent_on_phenylalanine_levels" YBR167C POP7 RPP2 rRNA_processing* ribonuclease_P_activity* ribonuclease_MRP_complex* None None 2 571885 571463 YBR167C S000000371 "ORF,_Verified" "Subunit_of_both_RNase_MRP,_which_cleaves_pre-rRNA,_and_nuclear_RNase_P,_which_cleaves_tRNA_precursors_to_generate_mature_5'_ends" YBR169C SSE2 None protein_folding molecular_function_unknown cytoplasm None None 2 575991 573910 YBR169C S000000373 "ORF,_Verified" Member_of_the_heat_shock_protein_70_(HSP70)_family;_may_be_involved_in_protein_folding;_localized_to_the_cytoplasm;_highly_homologous_to_the_heat_shock_protein_Sse1p YBR170C NPL4 HRD4 ER-associated_protein_catabolism molecular_function_unknown endoplasmic_reticulum* None Up 2 578081 576339 YBR170C S000000374 "ORF,_Verified" "Endoplasmic_reticulum_and_nuclear_membrane_protein,_forms_a_complex_with_Cdc48p_and_Ufd1p_that_recognizes_ubiquitinated_proteins_in_the_endoplasmic_reticulum_and_delivers_them_to_the_proteasome_for_degradation" YBR171W SEC66 SEC71|HSS1 filamentous_growth* protein_transporter_activity endoplasmic_reticulum_membrane* None None 2 578359 578979 YBR171W S000000375 "ORF,_Verified" "Non-essential_subunit_of_Sec63_complex_(Sec63p,_Sec62p,_Sec66p_and_Sec72p);_with_Sec61_complex,_Kar2p/BiP_and_Lhs1p_forms_a_channel_competent_for_SRP-dependent_and_post-translational_SRP-independent_protein_targeting_and_import_into_the_ER" YBR172C SMY2 None cytoskeleton_organization_and_biogenesis molecular_function_unknown cytoplasm None None 2 581367 579145 YBR172C S000000376 "ORF,_Verified" Protein_of_unknown_function_involved_in_COPII_vesicle_formation;_interacts_with_the_Sec23p/Sec24p_subcomplex;_overexpression_suppresses_the_temperature_sensitivity_of_a_myo2_mutant;_has_similarity_to_S._pombe_Mpd2 YBR173C UMP1 RNS2 ubiquitin-dependent_protein_catabolism* proteasome_activator_activity cytoplasm* None None 2 582167 581721 YBR173C S000000377 "ORF,_Verified" Short-lived_chaperone_required_for_correct_maturation_of_the_20S_proteasome;_may_inhibit_premature_dimerization_of_proteasome_half-mers;_degraded_by_proteasome_upon_completion_of_its_assembly YBR175W SWD3 SAF35|CPS30 chromatin_silencing_at_telomere* histone_lysine_N-methyltransferase_activity_(H3-K4_specific) COMPASS_complex None None 2 582403 583350 YBR175W S000000379 "ORF,_Verified" "Essential_subunit_of_the_COMPASS_(Set1C)_complex,_which_methylates_histone_H3_on_lysine_4_and_is_required_in_transcriptional_silencing_near_telomeres;_WD40_beta_propeller_superfamily_member_and_ortholog_of_mammalian_WDR5" YBR176W ECM31 None pantothenate_biosynthesis 3-methyl-2-oxobutanoate_hydroxymethyltransferase_activity mitochondrion None None 2 583715 584653 YBR176W S000000380 "ORF,_Verified" "Ketopantoate_hydroxymethyltransferase,_required_for_pantothenic_acid_biosynthesis,_converts_2-oxoisovalerate_into_2-dehydropantoate" YBR177C EHT1 None lipid_metabolism serine_hydrolase_activity mitochondrion* None None 2 586157 584802 YBR177C S000000381 "ORF,_Verified" Acyl-coenzymeA:ethanol_O-acyltransferase_that_plays_a_minor_role_in_medium-chain_fatty_acid_ethyl_ester_biosynthesis;_possesses_short-chain_esterase_activity;_localizes_to_lipid_particles_and_the_mitochondrial_outer_membrane YBR179C FZO1 None mitochondrion_organization_and_biogenesis* GTPase_activity mitochondrial_inner_membrane* None None 2 589109 586542 YBR179C S000000383 "ORF,_Verified" "Mitofusin,_mitochondrial_integral_membrane_protein_involved_in_mitochondrial_fusion_and_mitochondrial_genome_maintenance;_contains_N-terminal_GTPase_domain;_targeted_for_destruction_by_cytosolic_components_of_the_ubiquitin-proteasome_system" YBR180W DTR1 None spore_wall_assembly_(sensu_Fungi)* multidrug_transporter_activity* prospore_membrane None None 2 589736 591454 YBR180W S000000384 "ORF,_Verified" "Putative_dityrosine_transporter,_required_for_spore_wall_synthesis;_expressed_during_sporulation;_member_of_the_major_facilitator_superfamily_(DHA1_family)_of_multidrug_resistance_transporters" YBR181C RPS6B RPS102|RPS101|LPG18 protein_biosynthesis structural_constituent_of_ribosome cytoplasm* None None 2 592769 591707 YBR181C S000000385 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_identical_to_Rps6Ap_and_has_similarity_to_rat_S6_ribosomal_protein YBR182C SMP1 None positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_factor_activity* cytoplasm* None None 2 594859 593501 YBR182C S000000386 "ORF,_Verified" Putative_transcription_factor_involved_in_regulating_the_response_to_osmotic_stress;_member_of_the_MADS-box_family_of_transcription_factors YBR183W YPC1 None ceramide_metabolism ceramidase_activity endoplasmic_reticulum None None 2 596110 597060 YBR183W S000000387 "ORF,_Verified" "Alkaline_ceramidase_that_also_has_reverse_(CoA-independent)_ceramide_synthase_activity,_catalyzes_both_breakdown_and_synthesis_of_phytoceramide;_overexpression_confers_fumonisin_B1_resistance" YBR184W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 597358 598929 YBR184W S000000388 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YBR184W_is_not_an_essential_gene YBR185C MBA1 None aerobic_respiration* molecular_function_unknown mitochondrial_inner_membrane None None 2 599954 599118 YBR185C S000000389 "ORF,_Verified" Protein_involved_in_assembly_of_mitochondrial_respiratory_complexes;_may_act_as_a_receptor_for_proteins_destined_for_export_from_the_mitochondrial_matrix_to_the_inner_membrane YBR186W PCH2 None regulation_of_meiosis molecular_function_unknown nucleolus None None 2 600548 602355 YBR186W S000000390 "ORF,_Verified" "Nucleolar_component_of_the_pachytene_checkpoint,_which_prevents_chromosome_segregation_when_recombination_and_chromosome_synapsis_are_defective;_also_represses_meiotic_interhomolog_recombination_in_the_rDNA" YBR187W GDT1 None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) None None 2 602629 603471 YBR187W S000000391 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_expression_is_reduced_in_a_gcr1_null_mutant;_GFP-fusion_protein_localizes_to_the_vacuole;_expression_pattern_and_physical_interactions_suggest_a_possible_role_in_ribosome_biogenesis YBR188C NTC20 None "nuclear_mRNA_splicing,_via_spliceosome" "RNA_splicing_factor_activity,_transesterification_mechanism" spliceosome_complex None None 2 604102 603680 YBR188C S000000392 "ORF,_Verified" "Member_of_a_complex,_including_Prp19p,_that_binds_to_the_spliceosome;_required_for_pre-mRNA_splicing" YBR189W RPS9B SUP46|RPS13A protein_biosynthesis* structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota)* None None 2 604503 605503 YBR189W S000000393 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps9Ap_and_has_similarity_to_E._coli_S4_and_rat_S9_ribosomal_proteins YBR191W RPL21A URP1 protein_biosynthesis* structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 2 606265 607135 YBR191W S000000395 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl21Bp_and_has_similarity_to_rat_L21_ribosomal_protein" YBR192W RIM2 PYT1 mitochondrial_genome_maintenance* transporter_activity* mitochondrion None None 2 607647 608780 YBR192W S000000396 "ORF,_Verified" Mitochondrial_pyrimidine_nucleotide_transporter;_imports_pyrimidine_nucleoside_triphosphates_and_exports_pyrimidine_nucleoside_monophosphates;_member_of_the_mitochondrial_carrier_family YBR193C MED8 None transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_mediator_activity mediator_complex None None 2 609748 609077 YBR193C S000000397 "ORF,_Verified" Subunit_of_the_RNA_polymerase_II_mediator_complex;_associates_with_core_polymerase_subunits_to_form_the_RNA_polymerase_II_holoenzyme;_essential_for_transcriptional_regulation YBR194W None SOY1 biological_process_unknown molecular_function_unknown cytoplasm None None 2 610033 610404 YBR194W S000000398 "ORF,_Uncharacterized" Protein_proposed_to_be_associated_with_the_nuclear_pore_complex;_null_mutant_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation)_and_a_severe_growth_defect_in_minimal_glycerol_media YBR195C MSI1 CAC3 DNA_repair* transcription_regulator_activity chromatin_silencing_complex* None None 2 611877 610609 YBR195C S000000399 "ORF,_Verified" "Subunit_of_chromatin_assembly_factor_I_(CAF-1),_negative_regulator_of_the_RAS/cAMP_pathway_via_sequestration_of_Npr1p_kinase;_localizes_to_the_nucleus_and_cytoplasm;_homologous_to_human_retinoblastoma_binding_proteins_RbAp48_and_RbAp46" YBR196C PGI1 CDC30 glycolysis* glucose-6-phosphate_isomerase_activity cytosol None None 2 613895 612231 YBR196C S000000400 "ORF,_Verified" "Glycolytic_enzyme_phosphoglucose_isomerase,_catalyzes_the_interconversion_of_glucose-6-phosphate_and_fructose-6-phosphate;_required_for_cell_cycle_progression_and_completion_of_the_gluconeogenic_events_of_sporulation" YBR197C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 2 615851 615198 YBR197C S000000401 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_YBR197C_is_not_an_essential_gene YBR198C TAF5 TAF90 transcription_initiation_from_RNA_polymerase_II_promoter* general_RNA_polymerase_II_transcription_factor_activity SAGA_complex* None None 2 618518 616122 YBR198C S000000402 "ORF,_Verified" "Subunit_(90_kDa)_of_TFIID_and_SAGA_complexes,_involved_in_RNA_polymerase_II_transcription_initiation_and_in_chromatin_modification" YBR199W KTR4 None protein_amino_acid_N-linked_glycosylation mannosyltransferase_activity Golgi_apparatus None None 2 618904 620298 YBR199W S000000403 "ORF,_Verified" Putative_mannosyltransferase_involved_in_protein_glycosylation;_member_of_the_KRE2/MNT1_mannosyltransferase_family YBR200W BEM1 SRO1 establishment_of_cell_polarity_(sensu_Fungi)* protein_binding bud_neck* G2/M None 2 620867 622522 YBR200W S000000404 "ORF,_Verified" "Protein_containing_SH3-domains,_involved_in_establishing_cell_polarity_and_morphogenesis;_functions_as_a_scaffold_protein_for_complexes_that_include_Cdc24p,_Ste5p,_Ste20p,_and_Rsr1p" YBR201W DER1 None ER-associated_protein_catabolism molecular_function_unknown endoplasmic_reticulum_membrane None None 2 623572 624207 YBR201W S000000405 "ORF,_Verified" "Endoplasmic_reticulum_membrane_protein,_required_for_ER-associated_protein_degradation_of_misfolded_or_unassembled_proteins;_N-_and_C-_termini_protrude_into_the_cytoplasm,_has_similarity_to_Dfm1p" YBR202W MCM7 CDC47 DNA_replication_initiation* chromatin_binding* cytoplasm* M/G1 None 2 625767 628304 YBR202W S000000406 "ORF,_Verified" "Component_of_the_hexameric_MCM_complex,_which_is_important_for_priming_origins_of_DNA_replication_in_G1_and_becomes_an_active_ATP-dependent_helicase_that_promotes_DNA_melting_and_elongation_when_activated_by_Cdc7p-Dbf4p_in_S-phase" YBR203W COS111 None signal_transduction molecular_function_unknown cellular_component_unknown None None 2 629163 631937 YBR203W S000000407 "ORF,_Verified" "Protein_required_for_resistance_to_the_antifungal_drug_ciclopirox_olamine;_not_related_to_the_subtelomerically-encoded_COS_family;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YBR204C None None biological_process_unknown serine_hydrolase_activity lipid_particle M/G1 None 2 633376 632249 YBR204C S000000408 "ORF,_Uncharacterized" Serine_hydrolase;_YBR204C_is_not_an_essential_gene YBR205W KTR3 None cell_wall_organization_and_biogenesis* mannosyltransferase_activity membrane_fraction None None 2 633617 634831 YBR205W S000000409 "ORF,_Verified" "Putative_alpha-1,2-mannosyltransferase_involved_in_O-_and_N-linked_protein_glycosylation;_member_of_the_KRE2/MNT1_mannosyltransferase_family" YBR207W FTH1 None endocytosis* iron_ion_transporter_activity vacuolar_membrane_(sensu_Fungi) None None 2 635141 636538 YBR207W S000000411 "ORF,_Verified" Putative_high_affinity_iron_transporter_involved_in_transport_of_intravacuolar_stores_of_iron;_forms_complex_with_Fet5p;_expression_is_regulated_by_iron;_proposed_to_play_indirect_role_in_endocytosis YBR208C "DUR1,2" DUR80 allantoin_catabolism* allophanate_hydrolase_activity* cytoplasm None None 2 642205 636698 YBR208C S000000412 "ORF,_Verified" "Urea_amidolyase,_contains_both_urea_carboxylase_and_allophanate_hydrolase_activities,_degrades_urea_to_CO2_and_NH3;_expression_sensitive_to_nitrogen_catabolite_repression_and_induced_by_allophanate,_an_intermediate_in_allantoin_degradation" YBR210W ERV15 None axial_bud_site_selection molecular_function_unknown integral_to_membrane None None 2 645545 645973 YBR210W S000000414 "ORF,_Verified" "Protein_involved_in_export_of_proteins_from_the_endoplasmic_reticulum,_has_similarity_to_Erv14p" YBR211C AME1 ARP100 attachment_of_spindle_microtubules_to_kinetochore molecular_function_unknown spindle_pole_body* None None 2 647127 646153 YBR211C S000000415 "ORF,_Verified" "Essential_kinetochore_protein_associated_with_microtubules_and_spindle_pole_bodies;_component_of_the_kinetochore_sub-complex_COMA_(Ctf19p,_Okp1p,_Mcm21p,_Ame1p);_involved_in_spindle_checkpoint_maintenance" YBR214W SDS24 None endocytosis* molecular_function_unknown cytoplasm None None 2 651410 652993 YBR214W S000000418 "ORF,_Verified" "One_of_two_S._cerevisiae_homologs_(Sds23p_and_Sds24p)_of_the_Schizosaccharomyces_pombe_Sds23_protein,_which_genetic_studies_have_implicated_in_APC/cyclosome_regulation;_may_play_an_indirect_role_in_fluid-phase_endocytosis" YBR215W HPC2 None G1/S-specific_transcription_in_mitotic_cell_cycle transcription_regulator_activity nucleus None None 2 653351 655312 YBR215W S000000419 "ORF,_Verified" "Subunit_of_the_HIR_complex,_a_nucleosome_assembly_complex_involved_in_regulation_of_histone_gene_transcription;_mutants_display_synthetic_defects_with_subunits_of_FACT,_a_complex_that_allows_passage_of_RNA_Pol_II_through_nucleosomes" YBR216C YBP1 None response_to_oxidative_stress molecular_function_unknown cytoplasm None None 2 657595 655571 YBR216C S000000420 "ORF,_Verified" "Protein_required_for_oxidation_of_specific_cysteine_residues_of_the_transcription_factor_Yap1p,_resulting_in_the_nuclear_localization_of_Yap1p_in_response_to_stress" YBR218C PYC2 None gluconeogenesis* pyruvate_carboxylase_activity cytosol None None 2 662244 658702 YBR218C S000000422 "ORF,_Verified" "Pyruvate_carboxylase_isoform,_cytoplasmic_enzyme_that_converts_pyruvate_to_oxaloacetate;_highly_similar_to_isoform_Pyc1p_but_differentially_regulated;_mutations_in_the_human_homolog_are_associated_with_lactic_acidosis" YBR219C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 663298 662494 YBR219C S000000423 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YBR219C_is_not_an_essential_gene YBR220C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 664672 662990 YBR220C S000000424 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YBR220C_is_not_an_essential_gene YBR222C PCS60 FAT2 biological_process_unknown AMP_binding cytoplasm* None None 2 668346 666715 YBR222C S000000426 "ORF,_Verified" "Peroxisomal_AMP-binding_protein,_localizes_to_both_the_peroxisomal_peripheral_membrane_and_matrix,_expression_is_highly_inducible_by_oleic_acid,_similar_to_E._coli_long_chain_acyl-CoA_synthetase" YBR223C TDP1 None DNA_repair tyrosyl-DNA_phosophodiesterase_activity nucleus None None 2 670292 668658 YBR223C S000000427 "ORF,_Verified" "Tyrosyl-DNA_Phosphodiesterase_I,_hydrolyzes_3'-phosphotyrosyl_bonds_to_generate_3'-phosphate_DNA_and_tyrosine,_involved_in_the_repair_of_DNA_lesions_created_by_topoisomerase_I" YBR227C MCX1 None biological_process_unknown unfolded_protein_binding* mitochondrial_matrix None None 2 675129 673567 YBR227C S000000431 "ORF,_Verified" "Mitochondrial_ATP-binding_protein,_possibly_a_mitochondrial_chaperone_with_non-proteolytic_function;_similar_to_bacterial_ClpX_proteins" YBR228W SLX1 None DNA_repair* 5'-flap_endonuclease_activity nucleus None None 2 675308 676222 YBR228W S000000432 "ORF,_Verified" "Subunit_of_a_complex,_with_Slx4p,_that_hydrolyzes_5'_branches_from_duplex_DNA_in_response_to_stalled_or_converging_replication_forks;_function_overlaps_with_that_of_Sgs1p-Top3p" YBR230C OM14 None biological_process_unknown molecular_function_unknown mitochondrion None None 2 680045 679544 YBR230C S000000434 "ORF,_Verified" Integral_mitochondrial_outer_membrane_protein;_abundance_is_decreased_in_cells_grown_in_glucose_relative_to_other_carbon_sources;_appears_to_contain_3_alpha-helical_transmembrane_segments;_ORF_encodes_a_97-basepair_intron YBR231C SWC5 AOR1 chromatin_remodeling molecular_function_unknown nucleus* None None 2 683085 682174 YBR231C S000000435 "ORF,_Verified" "Protein_of_unknown_function,_component_of_the_SWR1_complex,_which_exchanges_histone_variant_H2AZ_(Htz1p)_for_chromatin-bound_histone_H2A" YBR233W PBP2 HEK1 biological_process_unknown molecular_function_unknown cytoplasm None None 2 683423 684664 YBR233W S000000437 "ORF,_Verified" "RNA_binding_protein_with_similarity_to_mammalian_heterogeneous_nuclear_RNP_K_protein,_involved_in_the_regulation_of_telomere_position_effect_and_telomere_length" YBR234C ARC40 None actin_filament_organization* structural_constituent_of_cytoskeleton Arp2/3_protein_complex None None 2 686587 685433 YBR234C S000000438 "ORF,_Verified" "Subunit_of_the_ARP2/3_complex,_which_is_required_for_the_motility_and_integrity_of_cortical_actin_patches" YBR235W None None biological_process_unknown ion_transporter_activity cellular_component_unknown None None 2 686896 690258 YBR235W S000000439 "ORF,_Uncharacterized" "Putative_ion_transporter,_similar_to_mammalian_electroneutral_Na(+)-(K+)-C1-_cotransporter_family;_YBR235W_is_not_an_essential_gene" YBR236C ABD1 None mRNA_capping mRNA_(guanine-N7-)-methyltransferase_activity nucleus* None None 2 691688 690378 YBR236C S000000440 "ORF,_Verified" "Methyltransferase,_catalyzes_the_transfer_of_a_methyl_group_from_S-adenosylmethionine_to_the_GpppN_terminus_of_capped_mRNA" YBR237W PRP5 RNA5 U2-type_nuclear_mRNA_branch_site_recognition "RNA_splicing_factor_activity,_transesterification_mechanism*" spliceosome_complex None None 2 691964 694513 YBR237W S000000441 "ORF,_Verified" "RNA_helicase_in_the_DEAD-box_family,_necessary_for_prespliceosome_formation,_bridges_U1_and_U2_snRNPs_and_enables_stable_U2_snRNP_association_with_intron_RNA" YBR238C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 2 697297 695102 YBR238C S000000442 "ORF,_Verified" Mitochondrial_membrane_protein_with_similarity_to_Rmd9p;_not_required_for_respiratory_growth_but_causes_a_synthetic_respiratory_defect_in_combination_with_rmd9_mutations;_transcriptionally_up-regulated_by_TOR;_deletion_increases_life_span YBR239C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 2 699938 698349 YBR239C S000000443 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_plays_a_role_in_restricting_Ty1_transposition YBR241C None None biological_process_unknown molecular_function_unknown vacuolar_membrane_(sensu_Fungi) None Up 2 704050 702584 YBR241C S000000445 "ORF,_Uncharacterized" "Putative_transporter,_member_of_the_sugar_porter_family;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuolar_membrane;_YBR241C_is_not_an_essential_gene" YBR242W None None biological_process_unknown molecular_function_unknown cytoplasm* G2/M None 2 704665 705381 YBR242W S000000446 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_YBR242W_is_not_an_essential_gene YBR243C ALG7 TUR1 protein_amino_acid_N-linked_glycosylation UDP-N-acetylglucosamine-dolichyl-phosphate_N-acetylglucosaminephosphotransferase_activity endoplasmic_reticulum S/G2 None 2 706788 705442 YBR243C S000000447 "ORF,_Verified" "UDP-N-acetyl-glucosamine-1-P_transferase,_transfers_Glc-Nac-P_from_UDP-GlcNac_to_Dol-P_in_the_ER_in_the_first_step_of_the_dolichol_pathway_of_protein_asparagine-linked_glycosylation;_inhibited_by_tunicamycin" YBR244W GPX2 AMI1 response_to_oxidative_stress glutathione_peroxidase_activity cytoplasm* None None 2 707523 708011 YBR244W S000000448 "ORF,_Verified" Phospholipid_hydroperoxide_glutathione_peroxidase_induced_by_glucose_starvation_that_protects_cells_from_phospholipid_hydroperoxides_and_nonphospholipid_peroxides_during_oxidative_stress YBR245C ISW1 SGN2 chromatin_remodeling* ATPase_activity ISW1_complex None None 2 711534 708145 YBR245C S000000449 "ORF,_Verified" "Member_of_the_imitation-switch_(ISWI)_class_of_ATP-dependent_chromatin_remodeling_complexes;_ATPase_that_forms_a_complex_with_Ioc2p_and_Ioc4p_to_regulate_transcription_elongation,_and_a_complex_with_Ioc3p_to_repress_transcription_initiation" YBR246W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 711586 712749 YBR246W S000000450 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_deletion_results_in_a_weak_carboxypeptidase_Y_missorting/secretion_phenotype;_YBR246W_is_not_an_essential_gene YBR247C ENP1 MEG1 35S_primary_transcript_processing* snoRNA_binding nucleus* None None 2 714450 712999 YBR247C S000000451 "ORF,_Verified" "Protein_associated_with_U3_and_U14_snoRNAs,_required_for_pre-rRNA_processing_and_40S_ribosomal_subunit_synthesis;_localized_in_the_nucleus_and_concentrated_in_the_nucleolus" YBR248C HIS7 None histidine_biosynthesis* imidazoleglycerol-phosphate_synthase_activity intracellular None Up 2 716460 714802 YBR248C S000000452 "ORF,_Verified" "Imidazole_glycerol_phosphate_synthase_(glutamine_amidotransferase:cyclase),_catalyzes_the_fifth_and_sixth_steps_of_histidine_biosynthesis_and_also_produces_5-aminoimidazole-4-carboxamide_ribotide_(AICAR),_a_purine_precursor" YBR250W SPO23 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 719028 720599 YBR250W S000000454 "ORF,_Verified" Protein_of_unknown_function;_associates_with_meiosis-specific_protein_Spo1p YBR251W MRPS5 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 2 721385 722308 YBR251W S000000455 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YBR252W DUT1 None pyrimidine_deoxyribonucleoside_triphosphate_catabolism dUTP_diphosphatase_activity cytoplasm* None None 2 722606 723049 YBR252W S000000456 "ORF,_Verified" "dUTPase,_catalyzes_hydrolysis_of_dUTP_to_dUMP_and_PPi,_thereby_preventing_incorporation_of_uracil_into_DNA_during_replication;_critical_for_the_maintenance_of_genetic_stability" YBR253W SRB6 MED22 transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_mediator_activity mediator_complex None None 2 723265 723630 YBR253W S000000457 "ORF,_Verified" Subunit_of_the_RNA_polymerase_II_mediator_complex;_associates_with_core_polymerase_subunits_to_form_the_RNA_polymerase_II_holoenzyme;_essential_for_transcriptional_regulation YBR254C TRS20 None ER_to_Golgi_transport molecular_function_unknown TRAPP_complex None None 2 724258 723731 YBR254C S000000458 "ORF,_Verified" One_of_10_subunits_of_the_transport_protein_particle_(TRAPP)_complex_of_the_cis-Golgi_which_mediates_vesicle_docking_and_fusion;_mutations_in_the_human_homolog_cause_the_spondyloepiphyseal_dysplasia_tarda_(SEDL)_disorder YBR255W None None biological_process_unknown molecular_function_unknown cytoplasm None None 2 724451 726535 YBR255W S000000459 "ORF,_Uncharacterized" "Protein_of_unknown_function,_required_for_normal_growth_rate_at_15_degrees_C;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern;_YBR255W_is_synthetically_sick_with_cdc13-1" YBR256C RIB5 None riboflavin_biosynthesis riboflavin_synthase_activity soluble_fraction S/G2 Up 2 728097 727381 YBR256C S000000460 "ORF,_Verified" Riboflavin_synthase;_catalyzes_the_last_step_of_the_riboflavin_biosynthesis_pathway YBR257W POP4 None rRNA_processing* ribonuclease_P_activity* ribonuclease_MRP_complex* None None 2 728880 729719 YBR257W S000000461 "ORF,_Verified" "Subunit_of_both_RNase_MRP,_which_cleaves_pre-rRNA,_and_nuclear_RNase_P,_which_cleaves_tRNA_precursors_to_generate_mature_5'_ends;_binds_to_the_RPR1_RNA_subunit_in_RNase_P" YBR258C SHG1 CPS15 histone_methylation histone_lysine_N-methyltransferase_activity_(H3-K4_specific) nucleus* None None 2 730157 729729 YBR258C S000000462 "ORF,_Verified" "Subunit_of_the_COMPASS_(Set1C)_complex,_which_methylates_histone_H3_on_lysine_4_and_is_required_in_transcriptional_silencing_near_telomeres" YBR260C RGD1 None osmosensory_signaling_pathway Rho_GTPase_activator_activity actin_cortical_patch* None Up 2 734634 732634 YBR260C S000000464 "ORF,_Verified" "GTPase-activating_protein_(RhoGAP)_for_Rho3p_and_Rho4p,_possibly_involved_in_control_of_actin_cytoskeleton_organization" YBR261C None None biological_process_unknown S-adenosylmethionine-dependent_methyltransferase_activity cytoplasm None None 2 735525 734827 YBR261C S000000465 "ORF,_Uncharacterized" Putative_S-adenosylmethionine-dependent_methyltransferase_of_the_seven_beta-strand_family;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YBR261C_is_not_an_essential_gene YBR262C None FMP51 biological_process_unknown molecular_function_unknown mitochondrion None None 2 736035 735715 YBR262C S000000466 "ORF,_Uncharacterized" Protein_of_unknown_function;_non-tagged_protein_is_detected_in_purified_mitochondria_in_high-throughput_studies;_null_mutant_displays_decreased_frequency_of_mitochondrial_genome_loss_and_reduced_growth_rate_in_minimal_glycerol_media YBR263W SHM1 TMP3|SHMT1 one-carbon_compound_metabolism glycine_hydroxymethyltransferase_activity mitochondrion None None 2 736259 737731 YBR263W S000000467 "ORF,_Verified" "Mitochondrial_serine_hydroxymethyltransferase,_converts_serine_to_glycine_plus_5,10_methylenetetrahydrofolate;_involved_in_generating_precursors_for_purine,_pyrimidine,_amino_acid,_and_lipid_biosynthesis;_reverse_reaction_generates_serine" YBR265W TSC10 None sphingolipid_biosynthesis* "oxidoreductase_activity,_acting_on_NADH_or_NADPH" cytoplasm* None None 2 738577 739539 YBR265W S000000469 "ORF,_Verified" "3-ketosphinganine_reductase,_catalyzes_the_second_step_in_phytosphingosine_synthesis,_essential_for_growth_in_the_absence_of_exogenous_dihydrosphingosine_or_phytosphingosine,_member_of_short_chain_dehydrogenase/reductase_protein_family" YBR267W REI1 None budding_cell_bud_growth* molecular_function_unknown cytoplasm None None 2 739836 741017 YBR267W S000000471 "ORF,_Verified" "Cytoplasmic_pre-60S_factor;_required_for_the_correct_recycling_of_shuttling_factors_Alb1,_Arx1_and_Tif6_at_the_end_of_the_ribosomal_large_subunit_biogenesis;_involved_in_bud_growth_in_the_mitotic_signaling_network" YBR268W MRPL37 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 2 741294 741611 YBR268W S000000472 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YBR269C None None biological_process_unknown molecular_function_unknown mitochondrion None None 2 742571 742155 YBR269C S000000473 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YBR270C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 744393 742756 YBR270C S000000474 "ORF,_Uncharacterized" Hypothetical_protein YBR271W None None biological_process_unknown S-adenosylmethionine-dependent_methyltransferase_activity cytoplasm None None 2 744847 746106 YBR271W S000000475 "ORF,_Uncharacterized" Putative_S-adenosylmethionine-dependent_methyltransferase_of_the_seven_beta-strand_family;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YBR271W_is_not_as_essential_gene YBR272C HSM3 None mismatch_repair molecular_function_unknown cytoplasm None None 2 747798 746356 YBR272C S000000476 "ORF,_Verified" "Protein_of_unknown_function,_involved_in_DNA_mismatch_repair_during_slow_growth;_has_weak_similarity_to_Msh1p" YBR273C UBX7 CUI3 ubiquitin-dependent_protein_catabolism* molecular_function_unknown endoplasmic_reticulum* M/G1 None 2 749366 748056 YBR273C S000000477 "ORF,_Verified" UBX_(ubiquitin_regulatory_X)_domain-containing_protein_that_interacts_with_Cdc48p YBR274W CHK1 None protein_amino_acid_phosphorylation* protein_kinase_activity nucleus None None 2 749589 751172 YBR274W S000000478 "ORF,_Verified" "Serine/threonine_kinase_and_DNA_damage_checkpoint_effector,_mediates_cell_cycle_arrest_via_phosphorylation_of_Pds1p;_phosphorylated_by_checkpoint_signal_transducer_Mec1p;_homolog_of_S._pombe_and_mammalian_Chk1_checkpoint_kinase" YBR276C PPS1 None protein_amino_acid_dephosphorylation* protein_tyrosine/threonine_phosphatase_activity cellular_component_unknown None None 2 760039 757616 YBR276C S000000480 "ORF,_Verified" "Protein_phosphatase_with_specificity_for_serine,_threonine,_and_tyrosine_residues;_has_a_role_in_the_DNA_synthesis_phase_of_the_cell_cycle" YBR278W DPB3 None chromatin_silencing_at_telomere* epsilon_DNA_polymerase_activity replication_fork* G1 None 2 760290 760895 YBR278W S000000482 "ORF,_Verified" "Third-largest_subunit_of_DNA_polymerase_II_(DNA_polymerase_epsilon),_required_to_maintain_fidelity_of_chromosomal_replication_and_also_for_inheritance_of_telomeric_silencing;_mRNA_abundance_peaks_at_the_G1/S_boundary_of_the_cell_cycle" YBR279W PAF1 None DNA_recombination* RNA_polymerase_II_transcription_elongation_factor_activity nucleus* None None 2 761253 762590 YBR279W S000000483 "ORF,_Verified" RNAP_II-associated_protein;_defines_large_complex_biochemically_and_functionally_distinct_from_the_Srb-Mediator_form_of_Pol_II_holoenzyme;_required_for_full_expression_of_a_subset_of_cell_cycle-regulated_genes;_homolog_of_human_PD2/hPAF1 YBR280C SAF1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None Up 2 764693 762780 YBR280C S000000484 "ORF,_Verified" F-Box_protein_involved_in_proteasome-dependent_degradation_of_Aah1p_during_entry_of_cells_into_quiescence;_interacts_with_Skp1 YBR281C DUG2 None biological_process_unknown molecular_function_unknown cytoplasm* None None 2 767602 764966 YBR281C S000000485 "ORF,_Verified" Probable_di-_and_tri-peptidase;_forms_a_complex_with_Dug1p_and_Dug3p_to_degrade_glutathione_(GSH)_and_other_peptides_containing_a_gamma-glu-X_bond_in_an_alternative_pathway_to_GSH_degradation_by_gamma-glutamyl_transpeptidase_(Ecm38p) YBR282W MRPL27 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 2 768236 768676 YBR282W S000000486 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YBR283C SSH1 None cotranslational_protein_targeting_to_membrane protein_transporter_activity endoplasmic_reticulum_membrane* None None 2 770411 768939 YBR283C S000000487 "ORF,_Verified" Subunit_of_the_Ssh1_translocon_complex;_Sec61p_homolog_involved_in_co-translational_pathway_of_protein_translocation;_not_essential YBR284W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 771235 773628 YBR284W S000000488 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YBR284W_is_not_an_essential_gene;_null_mutant_exhibits_decreased_resistance_to_rapamycin_and_wortmannin_and_synthetic_phenotype_with_alpha-synuclein YBR285W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 2 773918 774352 YBR285W S000000489 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YBR285W_is_not_an_essential_gene_and_deletion_of_YBR285W_leads_to_poor_growth_on_glucose-minimal_medium_at_15C YBR286W APE3 APY1 vacuolar_protein_catabolism aminopeptidase_activity vacuole_(sensu_Fungi) None None 2 774696 776309 YBR286W S000000490 "ORF,_Verified" "Vacuolar_aminopeptidase_Y,_processed_to_mature_form_by_Prb1p" YBR287W None ZSP1 biological_process_unknown molecular_function_unknown endoplasmic_reticulum G2/M None 2 776567 777850 YBR287W S000000491 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_ER;_YBR287W_is_not_an_essential_gene YBR289W SNF5 TYE4|SWI10|HAF4 chromatin_remodeling general_RNA_polymerase_II_transcription_factor_activity SWI/SNF_complex* None None 2 779663 782380 YBR289W S000000493 "ORF,_Verified" Subunit_of_the_SWI/SNF_chromatin_remodeling_complex_involved_in_transcriptional_regulation;_functions_interdependently_in_transcriptional_activation_with_Snf2p_and_Snf6p YBR290W BSD2 None protein_targeting_to_vacuole* molecular_function_unknown* endoplasmic_reticulum* None None 2 782587 783552 YBR290W S000000494 "ORF,_Verified" "Heavy_metal_ion_homeostasis_protein,_facilitates_trafficking_of_Smf1p_and_Smf2p_metal_transporters_to_the_vacuole_where_they_are_degraded,_controls_metal_ion_transport,_prevents_metal_hyperaccumulation,_functions_in_copper_detoxification" YBR291C CTP1 None mitochondrial_citrate_transport tricarboxylate_carrier_activity mitochondrial_inner_membrane None None 2 784568 783669 YBR291C S000000495 "ORF,_Verified" "Mitochondrial_inner_membrane_citrate_transporter,_member_of_the_mitochondrial_carrier_family" YBR293W VBA2 None basic_amino_acid_transport multidrug_transporter_activity* vacuolar_membrane_(sensu_Fungi) None None 2 787001 788425 YBR293W S000000497 "ORF,_Verified" Permease_of_basic_amino_acids_in_the_vacuolar_membrane YBR294W SUL1 SFP2 sulfate_transport sulfate_transporter_activity plasma_membrane None None 2 789230 791809 YBR294W S000000498 "ORF,_Verified" "High_affinity_sulfate_permease;_sulfate_uptake_is_mediated_by_specific_sulfate_transporters_Sul1p_and_Sul2p,_which_control_the_concentration_of_endogenous_activated_sulfate_intermediates" YBR296C PHO89 ITN1 phosphate_transport sodium:inorganic_phosphate_symporter_activity plasma_membrane M/G1 None 2 798516 796792 YBR296C S000000500 "ORF,_Verified" "Na+/Pi_cotransporter,_active_in_early_growth_phase;_similar_to_phosphate_transporters_of_Neurospora_crassa;_transcription_regulated_by_inorganic_phosphate_concentrations_and_Pho4p" YBR297W MAL33 MALR|MAL3R "regulation_of_transcription,_DNA-dependent*" transcription_factor_activity nucleus None None 2 800517 801923 YBR297W S000000501 "ORF,_Verified" "MAL-activator_protein,_part_of_complex_locus_MAL3;_nonfunctional_in_genomic_reference_strain_S288C" YBR298C MAL31 MALT|MAL3T alpha-glucoside_transport alpha-glucoside:hydrogen_symporter_activity membrane_fraction None None 2 804469 802625 YBR298C S000000502 "ORF,_Verified" "Maltose_permease,_high-affinity_maltose_transporter_(alpha-glucoside_transporter);_encoded_in_the_MAL3_complex_locus;_member_of_the_12_transmembrane_domain_superfamily_of_sugar_transporters;_functional_in_genomic_reference_strain_S288C" YBR299W MAL32 MALS|MAL3S maltose_catabolism alpha-glucosidase_activity cellular_component_unknown None None 2 805345 807099 YBR299W S000000503 "ORF,_Verified" "Maltase_(alpha-D-glucosidase),_inducible_protein_involved_in_maltose_catabolism;_encoded_in_the_MAL3_complex_locus;_functional_in_genomic_reference_strain_S288C" YBR301W DAN3 None biological_process_unknown molecular_function_unknown cell_wall_(sensu_Fungi) None None 2 809051 809413 YBR301W S000000505 "ORF,_Verified" "Cell_wall_mannoprotein_with_similarity_to_Tir1p,_Tir2p,_Tir3p,_and_Tir4p;_expressed_under_anaerobic_conditions,_completely_repressed_during_aerobic_growth" YBR302C COS2 None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) None None 2 811473 810334 YBR302C S000000506 "ORF,_Verified" "Protein_of_unknown_function,_member_of_the_DUP380_subfamily_of_conserved,_often_subtelomerically-encoded_proteins" YCL002C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 111674 110843 YCL002C S000000508 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YCL002C_is_not_an_essential_gene YCL004W PGS1 YCL003W|PEL1 phospholipid_biosynthesis CDP-diacylglycerol-glycerol-3-phosphate_3-phosphatidyltransferase_activity mitochondrion None None 3 109105 110670 YCL004W S000000510 "ORF,_Verified" "Phosphatidylglycerolphosphate_synthase,_catalyzes_the_synthesis_of_phosphatidylglycerolphosphate_from_CDP-diacylglycerol_and_sn-glycerol_3-phosphate_in_the_first_committed_and_rate-limiting_step_of_cardiolipin_biosynthesis" YCL008C STP22 VPS23 protein_targeting_to_vacuole* protein_binding endosome* None None 3 106853 105696 YCL008C S000000514 "ORF,_Verified" "Component_of_the_ESCRT-I_complex,_which_is_involved_in_ubiquitin-dependent_sorting_of_proteins_into_the_endosome;_homologous_to_the_mouse_and_human_Tsg101_tumor_susceptibility_gene;_mutants_exhibit_a_Class_E_Vps_phenotype" YCL009C ILV6 None branched_chain_family_amino_acid_biosynthesis enzyme_regulator_activity* mitochondrion* None None 3 105548 104619 YCL009C S000000515 "ORF,_Verified" "Regulatory_subunit_of_acetolactate_synthase,_which_catalyzes_the_first_step_of_branched-chain_amino_acid_biosynthesis;_enhances_activity_of_the_Ilv2p_catalytic_subunit,_localizes_to_mitochondria" YCL010C SGF29 None histone_acetylation molecular_function_unknown SAGA_complex None None 3 104350 103571 YCL010C S000000516 "ORF,_Verified" SaGa_associated_Factor_29kDa;_Probable_29kKDa_Subunit_of_SAGA_histone_acetyltransferase_complex YCL011C GBP2 RLF6 telomere_maintenance* RNA_binding* nucleus None None 3 103358 102075 YCL011C S000000517 "ORF,_Verified" "Poly(A+)_RNA-binding_protein,_involved_in_the_export_of_mRNAs_from_the_nucleus_to_the_cytoplasm;_similar_to_Hrb1p_and_Npl3p;_also_binds_single-stranded_telomeric_repeat_sequence_in_vitro" YCL014W BUD3 YCL012W cytokinesis* molecular_function_unknown bud_neck* S/G2 None 3 96281 101191 YCL012W S000000520 "ORF,_Verified" Protein_involved_in_bud-site_selection_and_required_for_axial_budding_pattern;_localizes_with_septins_to_bud_neck_in_mitosis_and_may_constitute_an_axial_landmark_for_next_round_of_budding YCL016C DCC1 None mitotic_sister_chromatid_cohesion molecular_function_unknown DNA_replication_factor_C_complex None None 3 95763 94621 YCL016C S000000521 "ORF,_Verified" "Subunit_of_a_complex_with_Ctf8p_and_Ctf18p_that_shares_some_components_with_Replication_Factor_C,_required_for_sister_chromatid_cohesion_and_telomere_length_maintenance" YCL017C NFS1 SPL1 iron_ion_homeostasis* cystathionine_gamma-lyase_activity mitochondrion None None 3 94270 92777 YCL017C S000000522 "ORF,_Verified" Cysteine_desulfurase_involved_in_iron-sulfur_cluster_(Fe/S)_biogenesis;_required_for_the_post-transcriptional_thio-modification_of_mitochondrial_and_cytoplasmic_tRNAs;_essential_protein_located_predominantly_in_mitochondria YCL018W LEU2 None leucine_biosynthesis 3-isopropylmalate_dehydrogenase_activity cytosol None None 3 91324 92418 YCL018W S000000523 "ORF,_Verified" "Beta-isopropylmalate_dehydrogenase_(IMDH),_catalyzes_the_third_step_in_the_leucine_biosynthesis_pathway" YCL020W None None None None None None None 3 85102 86418 YCL020W S000000525 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YCL024W KCC4 None protein_amino_acid_phosphorylation* protein_kinase_activity bud_neck G1 None 3 79162 82275 YCL024W S000000529 "ORF,_Verified" "Protein_kinase_of_the_bud_neck_involved_in_the_septin_checkpoint,_associates_with_septin_proteins,_negatively_regulates_Swe1p_by_phosphorylation,_shows_structural_homology_to_bud_neck_kinases_Gin4p_and_Hsl1p" YCL025C AGP1 YCC5 amino_acid_transport amino_acid_transporter_activity* plasma_membrane S/G2 None 3 77919 76018 YCL025C S000000530 "ORF,_Verified" "Low-affinity_amino_acid_permease_with_broad_substrate_range,_involved_in_uptake_of_asparagine,_glutamine,_and_other_amino_acids;_expression_is_regulated_by_the_SPS_plasma_membrane_amino_acid_sensor_system_(Ssy1p-Ptr3p-Ssy5p)" YCL026C-A FRM2 YCLX08C negative_regulation_of_fatty_acid_metabolism molecular_function_unknown cytoplasm* None None 3 75285 74704 YCL026C-A S000000589 "ORF,_Verified" "Protein_of_unknown_function,_involved_in_the_integration_of_lipid_signaling_pathways_with_cellular_homeostasis;_similar_to_bacterial_nitroreductases" YCL027W FUS1 None conjugation_with_cellular_fusion* molecular_function_unknown plasma_membrane* M/G1 None 3 71803 73341 YCL027W S000000532 "ORF,_Verified" "Membrane_protein_localized_to_the_shmoo_tip,_required_for_cell_fusion;_expression_regulated_by_mating_pheromone;_proposed_to_coordinate_signaling,_fusion,_and_polarization_events_required_for_fusion;_potential_Cdc28p_substrate" YCL030C HIS4 None histidine_biosynthesis phosphoribosyl-ATP_diphosphatase_activity* intracellular None Up 3 68333 65934 YCL030C S000000535 "ORF,_Verified" "Multifunctional_enzyme_containing_phosphoribosyl-ATP_pyrophosphatase,_phosphoribosyl-AMP_cyclohydrolase,_and_histidinol_dehydrogenase_activities;_catalyzes_the_second,_third,_ninth_and_tenth_steps_in_histidine_biosynthesis" YCL031C RRP7 None 35S_primary_transcript_processing* molecular_function_unknown nucleus* None None 3 65568 64675 YCL031C S000000536 "ORF,_Verified" Essential_protein_involved_in_rRNA_processing_and_ribosome_biogenesis YCL032W STE50 None signal_transduction_during_conjugation_with_cellular_fusion* protein_kinase_regulator_activity cytoplasm None None 3 63441 64481 YCL032W S000000537 "ORF,_Verified" "Protein_involved_in_mating_response,_invasive/filamentous_growth,_and_osmotolerance,_acts_as_an_adaptor_that_links_G_protein-associated_Cdc42p-Ste20p_complex_to_the_effector_Ste11p_to_modulate_signal_transduction" YCL034W LSB5 None endocytosis* molecular_function_unknown cell_cortex None None 3 61658 62722 YCL034W S000000539 "ORF,_Verified" "Protein_of_unknown_function;_binds_Las17p,_which_is_a_homolog_of_human_Wiskott-Aldrich_Syndrome_protein_involved_in_actin_patch_assembly_and_actin_polymerization" YCL035C GRX1 None response_to_oxidative_stress* thiol-disulfide_exchange_intermediate_activity* cytoplasm* None None 3 61173 60841 YCL035C S000000540 "ORF,_Verified" Hydroperoxide_and_superoxide-radical_responsive_heat-stable_glutathione-dependent_disulfide_oxidoreductase_with_active_site_cysteine_pair;_protects_cells_from_oxidative_damage YCL036W GFD2 YCD6 biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 59026 60726 YCL036W S000000541 "ORF,_Verified" "Protein_of_unknown_function,_identified_as_a_high-copy_suppressor_of_a_dbp5_mutation" YCL037C SRO9 None protein_biosynthesis RNA_binding polysome None None 3 58678 57374 YCL037C S000000542 "ORF,_Verified" "Cytoplasmic_RNA-binding_protein_that_associates_with_translating_ribosomes;_involved_in_heme_regulation_of_Hap1p_as_a_component_of_the_HMC_complex,_also_involved_in_the_organization_of_actin_filaments;_contains_a_La_motif" YCL038C ATG22 AUT4 protein_targeting_to_vacuole* molecular_function_unknown integral_to_membrane* G2/M None 3 56527 54941 YCL038C S000000543 "ORF,_Verified" Vacuolar_integral_membrane_protein_required_for_efflux_of_amino_acids_during_autophagic_body_breakdown_in_the_vacuole;_null_mutation_causes_a_gradual_loss_of_viability_during_starvation YCL039W GID7 MOH2 negative_regulation_of_gluconeogenesis molecular_function_unknown cytoplasm* None None 3 52645 54882 YCL039W S000000544 "ORF,_Verified" "Protein_of_unknown_function,_involved_in_proteasome-dependent_catabolite_inactivation_of_fructose-1,6-bisphosphatase;_contains_six_WD40_repeats;_computational_analysis_suggests_that_Gid7p_and_Moh1p_have_similar_functions" YCL040W GLK1 HOR3 glucose_metabolism* glucokinase_activity cytosol M/G1 None 3 50838 52340 YCL040W S000000545 "ORF,_Verified" "Glucokinase,_catalyzes_the_phosphorylation_of_glucose_at_C6_in_the_first_irreversible_step_of_glucose_metabolism;_one_of_three_glucose_phosphorylating_enzymes;_expression_regulated_by_non-fermentable_carbon_sources" YCL042W None None biological_process_unknown molecular_function_unknown cytoplasm G1 None 3 50584 50943 YCL042W S000000547 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_epitope-tagged_protein_localizes_to_the_cytoplasm YCL043C PDI1 TRG1|MFP1 protein_folding protein_disulfide_isomerase_activity endoplasmic_reticulum_lumen G2/M None 3 50221 48653 YCL043C S000000548 "ORF,_Verified" "Protein_disulfide_isomerase,_multifunctional_protein_resident_in_the_endoplasmic_reticulum_lumen,_essential_for_the_formation_of_disulfide_bonds_in_secretory_and_cell-surface_proteins,_unscrambles_non-native_disulfide_bonds" YCL044C MGR1 None mitochondrial_genome_maintenance molecular_function_unknown mitochondrion* None None 3 48364 47111 YCL044C S000000549 "ORF,_Verified" "Subunit,_with_Yme1p,_of_the_mitochondrial_inner_membrane_i-AAA_protease_complex,_which_is_responsible_for_degradation_of_unfolded_or_misfolded_mitochondrial_gene_products;_required_for_growth_of_cells_lacking_the_mitochondrial_genome" YCL047C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 44437 43661 YCL047C S000000552 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YCL049C None None biological_process_unknown molecular_function_unknown membrane_fraction None None 3 40724 39786 YCL049C S000000554 "ORF,_Uncharacterized" Protein_of_unknown_function;_localizes_to_membrane_fraction;_YCL049C_is_not_an_essential_gene; YCL050C APA1 DTP1 nucleotide_metabolism bis(5'-nucleosyl)-tetraphosphatase_activity cytoplasm* None None 3 38801 37836 YCL050C S000000555 "ORF,_Verified" "Diadenosine_5',5''-P1,P4-tetraphosphate_phosphorylase_I_(AP4A_phosphorylase),_involved_in_catabolism_of_bis(5'-nucleosidyl)_tetraphosphates;_has_similarity_to_Apa2p" YCL051W LRE1 None cell_wall_organization_and_biogenesis* transcription_regulator_activity* cell_wall_(sensu_Fungi) None None 3 35865 37616 YCL051W S000000556 "ORF,_Verified" Protein_involved_in_control_of_cell_wall_structure_and_stress_response;_inhibits_Cbk1p_protein_kinase_activity;_overproduction_confers_resistance_to_cell-wall_degrading_enzymes YCL052C PBN1 None GPI_anchor_biosynthesis* mannosyltransferase_activity endoplasmic_reticulum None None 3 35393 34143 YCL052C S000000557 "ORF,_Verified" "Essential_component_of_glycosylphosphatidylinositol-mannosyltransferase_I,_required_for_the_autocatalytic_post-translational_processing_of_the_protease_B_precursor_Prb1p,_localizes_to_ER_in_lumenal_orientation;_homolog_of_mammalian_PIG-X" YCL054W SPB1 None processing_of_27S_pre-rRNA S-adenosylmethionine-dependent_methyltransferase_activity* nucleus* None None 3 31449 33974 YCL054W S000000559 "ORF,_Verified" "AdoMet-dependent_methyltransferase_involved_in_rRNA_processing_and_60S_ribosomal_subunit_maturation;_methylates_G2922_in_the_tRNA_docking_site_of_the_large_subunit_rRNA_and_in_the_absence_of_snR52,_U2921;_suppressor_of_PAB1_mutants" YCL055W KAR4 None meiosis* transcription_regulator_activity nucleus G1 Up 3 27929 28936 YCL055W S000000560 "ORF,_Verified" "Transcription_factor_required_for_gene_regulation_in_repsonse_to_pheromones;_also_required_during_meiosis;_exists_in_two_forms,_a_slower-migrating_form_more_abundant_during_vegetative_growth_and_a_faster-migrating_form_induced_by_pheromone" YCL056C None None biological_process_unknown molecular_function_unknown cytoplasm None None 3 27359 26925 YCL056C S000000561 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern YCL057W PRD1 None proteolysis metalloendopeptidase_activity* cytoplasm* None None 3 24768 26906 YCL057W S000000562 "ORF,_Verified" "Zinc_metalloendopeptidase,_found_in_the_cytoplasm_and_intermembrane_space_of_mitochondria;_with_Cym1p,_involved_in_degradation_of_mitochondrial_proteins_and_of_presequence_peptides_cleaved_from_imported_proteins" YCL059C KRR1 None 35S_primary_transcript_processing* molecular_function_unknown nucleolus* None None 3 23379 22429 YCL059C S000000564 "ORF,_Verified" Essential_nucleolar_protein_required_for_the_synthesis_of_18S_rRNA_and_for_the_assembly_of_40S_ribosomal_subunit YCL061C MRC1 YCL060C chromatin_silencing_at_telomere* molecular_function_unknown nucleus* G1 None 3 22106 18816 YCL061C S000000566 "ORF,_Verified" "S-phase_checkpoint_protein_found_at_replication_forks,_required_for_DNA_replication;_also_required_for_Rad53p_activation_during_DNA_replication_stress,_where_it_forms_a_replication-pausing_complex_with_Tof1p_and_is_phosphorylated_by_Mec1p" YCL063W VAC17 YCL062W vacuole_inheritance receptor_activity vacuolar_membrane S/G2 None 3 17290 18561 YCL063W S000000568 "ORF,_Verified" Protein_involved_in_vacuole_inheritance;_acts_as_a_vacuole-specific_receptor_for_myosin_Myo2p YCL064C CHA1 None threonine_catabolism* L-serine_ammonia-lyase_activity* mitochondrion* None None 3 16880 15798 YCL064C S000000569 "ORF,_Verified" "Catabolic_L-serine_(L-threonine)_deaminase,_catalyzes_the_degradation_of_both_L-serine_and_L-threonine;_required_to_use_serine_or_threonine_as_the_sole_nitrogen_source,_transcriptionally_induced_by_serine_and_threonine" YCL066W HMLALPHA1 ALPHA1 regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_coactivator_activity nucleus G2/M None 3 13282 13809 YCL066W S000000571 "ORF,_Verified|silenced_gene" "Silenced_copy_of_ALPHA1_at_HML,_encoding_a_transcriptional_coactivator_involved_in_the_regulation_of_mating-type_alpha-specific_gene_expression" YCL068C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 12285 11503 YCL068C S000000573 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YCL069W VBA3 None basic_amino_acid_transport basic_amino_acid_permease_activity vacuolar_membrane_(sensu_Fungi) None None 3 9706 11082 YCL069W S000000574 "ORF,_Verified" Permease_of_basic_amino_acids_in_the_vacuolar_membrane YCL073C None None transport transporter_activity membrane None None 3 8326 6479 YCL073C S000000575 "ORF,_Uncharacterized" Protein_of_unconfirmed_function;_displays_a_topology_characteristic_of_the_Major_Facilitators_Superfamily_of_membrane_proteins;_coding_sequence_98%_identical_to_that_of_YKR106W YCR002C CDC10 None cell_wall_organization_and_biogenesis* GTPase_activity* septin_ring_(sensu_Saccharomyces) S/G2 None 3 118346 117378 YCR002C S000000595 "ORF,_Verified" "Component_of_the_septin_ring_of_the_mother-bud_neck_that_is_required_for_cytokinesis;_septins_recruit_proteins_to_the_neck_and_can_act_as_a_barrier_to_diffusion_at_the_membrane,_and_they_comprise_the_10nm_filaments_seen_with_EM" YCR003W MRPL32 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 3 118618 119169 YCR003W S000000596 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YCR004C YCP4 None biological_process_unknown electron_transporter_activity cytoplasm* None None 3 120316 119573 YCR004C S000000597 "ORF,_Verified" "Protein_of_unknown_function,_has_sequence_and_structural_similarity_to_flavodoxins;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YCR005C CIT2 None glutamate_biosynthesis* citrate_(Si)-synthase_activity mitochondrion* None None 3 122326 120944 YCR005C S000000598 "ORF,_Verified" "Citrate_synthase,_catalyzes_the_condensation_of_acetyl_coenzyme_A_and_oxaloacetate_to_form_citrate,_peroxisomal_isozyme_involved_in_glyoxylate_cycle;_expression_is_controlled_by_Rtg1p_and_Rtg2p_transcription_factors" YCR007C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 126728 126009 YCR007C S000000600 "ORF,_Uncharacterized" "Putative_integral_membrane_protein,_member_of_DUP240_gene_family;_YCR007C_is_not_an_essential_gene" YCR009C RVS161 SPE161|FUS7|END6 endocytosis* cytoskeletal_protein_binding actin_cortical_patch* None None 3 131540 130743 YCR009C S000000602 "ORF,_Verified" "Amphiphysin-like_lipid_raft_protein;_subunit_of_a_complex_(Rvs161p-Rvs167p)_that_regulates_polarization_of_the_actin_cytoskeleton,_endocytosis,_cell_polarity,_cell_fusion_and_viability_following_starvation_or_osmotic_stress" YCR010C ADY2 ATO1 meiosis* ammonium_transporter_activity* mitochondrion* None None 3 133122 132271 YCR010C S000000603 "ORF,_Verified" Acetate_transporter_required_for_normal_sporulation;_phosphorylated_in_mitochondria YCR011C ADP1 None transport "ATPase_activity,_coupled_to_transmembrane_movement_of_substances" cytoplasm* None Up 3 136871 133722 YCR011C S000000604 "ORF,_Verified" Putative_ATP-dependent_permease_of_the_ABC_transporter_family_of_proteins YCR012W PGK1 None glycolysis* phosphoglycerate_kinase_activity cytoplasm None None 3 137744 138994 YCR012W S000000605 "ORF,_Verified" "3-phosphoglycerate_kinase,_catalyzes_transfer_of_high-energy_phosphoryl_groups_from_the_acyl_phosphate_of_1,3-bisphosphoglycerate_to_ADP_to_produce_ATP;_key_enzyme_in_glycolysis_and_gluconeogenesis" YCR014C POL4 POLX double-strand_break_repair_via_nonhomologous_end-joining* beta_DNA_polymerase_activity nucleus None None 3 140931 139183 YCR014C S000000607 "ORF,_Verified" "DNA_polymerase_IV,_undergoes_pair-wise_interactions_with_Dnl4p-Lif1p_and_Rad27p_to_mediate_repair_of_DNA_double-strand_breaks_by_non-homologous_end_joining_(NHEJ);_homologous_to_mammalian_DNA_polymerase_beta" YCR016W None None biological_process_unknown molecular_function_unknown nucleus* None None 3 143632 144504 YCR016W S000000609 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleolus_and_nucleus;_YCR016W_is_not_an_essential_gene YCR017C CWH43 None cell_wall_organization_and_biogenesis* molecular_function_unknown bud_neck* None None 3 147632 144771 YCR017C S000000610 "ORF,_Verified" Putative_sensor/transporter_protein_involved_in_cell_wall_biogenesis;_contains_14-16_transmembrane_segments_and_several_putative_glycosylation_and_phosphorylation_sites;_null_mutation_is_synthetically_lethal_with_pkc1_deletion YCR018C SRD1 None rRNA_processing molecular_function_unknown cytoplasm* M/G1 None 3 148901 148236 YCR018C S000000611 "ORF,_Verified" Protein_involved_in_the_processing_of_pre-rRNA_to_mature_rRNA;_contains_a_C2/C2_zinc_finger_motif;_srd1_mutation_suppresses_defects_caused_by_the_rrp1-1_mutation YCR020C PET18 HIT2 mitochondrion_organization_and_biogenesis* molecular_function_unknown cellular_component_unknown None None 3 154657 154010 YCR020C S000000613 "ORF,_Verified" Protein_required_for_respiratory_growth_and_stability_of_the_mitochondrial_genome YCR021C HSP30 YRO1 response_to_stress molecular_function_unknown plasma_membrane None None 3 157103 156105 YCR021C S000000615 "ORF,_Verified" "Hydrophobic_plasma_membrane_localized,_stress-responsive_protein_that_negatively_regulates_the_H(+)-ATPase_Pma1p;_induced_by_heat_shock,_ethanol_treatment,_weak_organic_acid,_glucose_limitation,_and_entry_into_stationary_phase" YCR023C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 160369 158534 YCR023C S000000617 "ORF,_Verified" Vacuolar_membrane_protein_of_unknown_function;_member_of_the_multidrug_resistance_family;_YCR023C_is_not_an_essential_gene YCR024C SLM5 None protein_biosynthesis asparagine-tRNA_ligase_activity mitochondrion None None 3 162218 160740 YCR024C S000000618 "ORF,_Verified" Mitochondrial_asparaginyl-tRNA_synthetase YCR024C-A PMP1 None cation_transport enzyme_regulator_activity plasma_membrane* G2/M None 3 163063 162941 YCR024C-A S000000619 "ORF,_Verified" "Small_single-membrane_span_proteolipid_that_functions_as_a_regulatory_subunit_of_the_plasma_membrane_H(+)-ATPase_Pma1p,_forms_unique_helix_and_positively_charged_cytoplasmic_domain_that_is_able_to_specifically_segregate_phosphatidylserines" YCR028C-A RIM1 None mitochondrial_genome_maintenance single-stranded_DNA_binding mitochondrion* None None 3 173436 172946 YCR028C-A S000007222 "ORF,_Verified" Single-stranded_DNA-binding_protein_essential_for_mitochondrial_genome_maintenance;_involved_in_mitochondrial_DNA_replication YCR030C SYP1 YCR029C-A biological_process_unknown molecular_function_unknown bud_neck* None None 3 176434 173822 YCR030C S000000626 "ORF,_Verified" Protein_with_a_potential_role_in_actin_cytoskeletal_organization;_overexpression_suppresses_a_pfy1_(profilin)_null_mutation YCR031C RPS14A RPL59|CRY1 protein_biosynthesis* structural_constituent_of_ribosome* cytosolic_small_ribosomal_subunit_(sensu_Eukaryota)* None None 3 178216 177496 YCR031C S000000627 "ORF,_Verified" "Ribosomal_protein_59_of_the_small_subunit,_required_for_ribosome_assembly_and_20S_pre-rRNA_processing;_mutations_confer_cryptopleurine_resistance;_nearly_identical_to_Rps14Bp_and_similar_to_E._coli_S11_and_rat_S14_ribosomal_proteins" YCR034W FEN1 VBM2|GNS1|ELO2 vesicle-mediated_transport* fatty_acid_elongase_activity endoplasmic_reticulum* None Down 3 190588 191631 YCR034W S000000630 "ORF,_Verified" "Fatty_acid_elongase,_involved_in_sphingolipid_biosynthesis;_acts_on_fatty_acids_of_up_to_24_carbons_in_length;_mutations_have_regulatory_effects_on_1,3-beta-glucan_synthase,_vacuolar_ATPase,_and_the_secretory_pathway" YCR037C PHO87 None phosphate_transport inorganic_phosphate_transporter_activity membrane None None 3 197181 194410 YCR037C S000000633 "ORF,_Verified" "Low-affinity_inorganic_phosphate_(Pi)_transporter,_involved_in_activation_of_PHO_pathway;_expression_is_independent_of_Pi_concentration_and_Pho4p_activity;_contains_12_membrane-spanning_segments" YCR039C MATALPHA2 ALPHA2 regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_corepressor_activity nucleus None None 3 200174 199542 YCR039C S000000635 "ORF,_Verified" "Homeobox-domain_protein_that,_with_Mcm1p,_represses_a-specific_genes_in_haploids;_acts_with_A1p_to_repress_transcription_of_haploid-specific_genes_in_diploids;_one_of_two_genes_encoded_by_the_MATalpha_mating_type_cassette" YCR040W MATALPHA1 ALPHA1 regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_coactivator_activity nucleus G2/M None 3 200438 200965 YCR040W S000000636 "ORF,_Verified" Transcriptional_co-activator_involved_in_regulation_of_mating-type-specific_gene_expression;_targets_the_transcription_factor_Mcm1p_to_the_promoters_of_alpha-specific_genes;_one_of_two_genes_encoded_by_the_MATalpha_mating_type_cassette YCR043C None None biological_process_unknown molecular_function_unknown Golgi_apparatus None None 3 206640 206257 YCR043C S000000639 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_Golgi_apparatus;_YCR043C_is_not_an_essential_gene YCR044C PER1 COS16 response_to_unfolded_protein* molecular_function_unknown vacuolar_membrane_(sensu_Fungi) None None 3 207946 206873 YCR044C S000000640 "ORF,_Verified" "Protein_of_the_endoplasmic_reticulum,_required_for_GPI-phospholipase_A2_activity_that_remodels_the_GPI_anchor_as_a_prerequisite_for_association_of_GPI-anchored_proteins_with_lipid_rafts;_functionally_complemented_by_human_ortholog_PERLD1" YCR045C None None biological_process_unknown serine-type_peptidase_activity cellular_component_unknown None None 3 209606 208131 YCR045C S000000641 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YCR046C IMG1 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 3 210419 209910 YCR046C S000000642 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_large_subunit,_required_for_respiration_and_for_maintenance_of_the_mitochondrial_genome" YCR047C BUD23 None bud_site_selection S-adenosylmethionine-dependent_methyltransferase_activity cytoplasm* None None 3 211541 210714 YCR047C S000000643 "ORF,_Verified" Protein_involved_in_bud-site_selection;_diploid_mutants_display_a_random_budding_pattern_instead_of_the_wild-type_bipolar_pattern YCR048W ARE1 SAT2 sterol_metabolism sterol_O-acyltransferase_activity endoplasmic_reticulum None None 3 211925 213757 YCR048W S000000644 "ORF,_Verified" "Acyl-CoA:sterol_acyltransferase,_isozyme_of_Are2p;_endoplasmic_reticulum_enzyme_that_contributes_the_major_sterol_esterification_activity_in_the_absence_of_oxygen" YCR050C None None None None None None None 3 213768 213460 YCR050C S000000646 "ORF,_Uncharacterized" Non-essential_protein_of_unknown_function;_deletion_mutant_is_synthetically_sick_or_lethal_with_alpha-synuclein YCR051W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 3 214067 214735 YCR051W S000000647 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_contains_ankyrin_(Ank)_repeats;_YCR051W_is_not_an_essential_gene YCR054C CTR86 None biological_process_unknown molecular_function_unknown cytoplasm None None 3 220063 218372 YCR054C S000000650 "ORF,_Verified" Essential_protein_of_unknown_function;_upstream_region_contains_a_Gcn4p_responsive_site_suggesting_a_possible_role_in_amino_acid_biosynthesis YCR057C PWP2 UTP1|YCR058C|YCR055C 35S_primary_transcript_processing* snoRNA_binding cytoplasm* None None 3 223224 220453 YCR057C S000000653 "ORF,_Verified" "Conserved_90S_pre-ribosomal_component_essential_for_proper_endonucleolytic_cleavage_of_the_35_S_rRNA_precursor_at_A0,_A1,_and_A2_sites;_contains_eight_WD-repeats;_PWP2_deletion_leads_to_defects_in_cell_cycle_and_bud_morphogenesis" YCR059C YIH1 None regulation_of_amino_acid_metabolism molecular_function_unknown cytoplasm* None None 3 224226 223450 YCR059C S000000655 "ORF,_Verified" "Protein_that_inhibits_activation_of_Gcn2p,_an_eIF2_alpha_subunit_protein_kinase,_by_competing_for_Gcn1p_binding,_thus_impacting_gene_expression_in_response_to_starvation;_has_sequence_and_functional_similarity_to_the_mouse_IMPACT_gene" YCR060W TAH1 None protein_folding chaperone_binding cytoplasm* None None 3 224395 224730 YCR060W S000000656 "ORF,_Verified" "HSP90_cofactor;_interacts_with_Hsp82p,_Pih1p,_Rvb1_and_Rvb2,_contains_a_single_TPR_domain_with_at_least_two_TPR_motifs" YCR061W None YCR062W biological_process_unknown molecular_function_unknown cytoplasm None None 3 225559 227454 YCR061W S000000657 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern;_induced_by_treatment_with_8-methoxypsoralen_and_UVA_irradiation YCR063W BUD31 CWC14 bud_site_selection* molecular_function_unknown nucleus None None 3 228314 228787 YCR063W S000000659 "ORF,_Verified" Protein_involved_in_bud-site_selection;_analysis_of_integrated_high-throughput_datasets_predicts_an_involvement_in_RNA_splicing;_diploid_mutants_display_a_random_budding_pattern_instead_of_the_wild-type_bipolar_pattern YCR065W HCM1 None transcription_initiation_from_RNA_polymerase_II_promoter* specific_RNA_polymerase_II_transcription_factor_activity nucleus G1 None 3 229306 231000 YCR065W S000000661 "ORF,_Verified" "Forkhead_transcription_factor_that_drives_S-phase_specific_expression_of_genes_involved_in_chromosome_segregation,_spindle_dynamics,_and_budding;_suppressor_of_calmodulin_mutants_with_specific_SPB_assembly_defects;_telomere_maintenance_role" YCR066W RAD18 None DNA_repair ubiquitin_conjugating_enzyme_activity* nuclear_chromatin None None 3 231496 232959 YCR066W S000000662 "ORF,_Verified" Protein_involved_in_postreplication_repair;_binds_single-stranded_DNA_and_has_single-stranded_DNA_dependent_ATPase_activity;_forms_heterodimer_with_Rad6p;_contains_RING-finger_motif YCR069W CPR4 SCC3|YCR070W|CYP4 biological_process_unknown peptidyl-prolyl_cis-trans_isomerase_activity membrane S/G2 None 3 239051 240007 YCR069W S000000665 "ORF,_Verified" "Peptidyl-prolyl_cis-trans_isomerase_(cyclophilin),_catalyzes_the_cis-trans_isomerization_of_peptide_bonds_N-terminal_to_proline_residues;_has_a_potential_role_in_the_secretory_pathway" YCR071C IMG2 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 3 240539 240099 YCR071C S000000667 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YCR072C RSA4 None ribosomal_large_subunit_assembly_and_maintenance molecular_function_unknown nucleolus None None 3 242348 240801 YCR072C S000000668 "ORF,_Verified" "WD-repeat_protein_involved_in_ribosome_biogenesis;_may_interact_with_ribosomes;_required_for_maturation_and_efficient_intra-nuclear_transport_or_pre-60S_ribosomal_subunits,_localizes_to_the_nucleolus" YCR076C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 250042 249290 YCR076C S000000672 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YCR076C_is_not_an_essential_gene YCR077C PAT1 MRT1 chromosome_segregation* molecular_function_unknown cytosolic_small_ribosomal_subunit_(sensu_Eukaryota)* None None 3 252625 250235 YCR077C S000000673 "ORF,_Verified" "Topoisomerase_II-associated_deadenylation-dependent_mRNA-decapping_factor;_also_required_for_faithful_chromosome_transmission,_maintenance_of_rDNA_locus_stability,_and_protection_of_mRNA_3'-UTRs_from_trimming;_functionally_linked_to_Pab1p" YCR079W PTC6 PPP2|AUP1 biological_process_unknown phosphoprotein_phosphatase_activity mitochondrion None None 3 252842 254170 YCR079W S000002133 "ORF,_Verified" Mitochondrial_protein_phosphatase_of_type_2C_with_similarity_to_mammalian_PP1Ks;_involved_in_mitophagy;_null_mutant_is_sensitive_to_rapamycin_and_has_decreased_phosphorylation_of_the_Pda1_subunit_of_pyruvate_dehydrogenase YCR082W AHC2 None biological_process_unknown molecular_function_unknown cytoplasm* None None 3 258880 259266 YCR082W S000000678 "ORF,_Verified" "Protein_of_unknown_function,_putative_transcriptional_regulator;_proposed_to_be_a_Ada_Histone_acetyltransferase_complex_component;_GFP_tagged_protein_is_localized_to_the_cytoplasm_and_nucleus" YCR083W TRX3 None response_to_oxidative_stress thiol-disulfide_exchange_intermediate_activity mitochondrion None None 3 259575 259958 YCR083W S000000679 "ORF,_Verified" "Mitochondrial_thioredoxin,_highly_conserved_oxidoreductase_required_to_maintain_the_redox_homeostasis_of_the_cell,_forms_the_mitochondrial_thioredoxin_system_with_Trr2p,_redox_state_is_maintained_by_both_Trr2p_and_Glr1p" YCR086W CSM1 None DNA_replication* molecular_function_unknown nucleolus* None None 3 263389 263961 YCR086W S000000682 "ORF,_Verified" "Nucleolar_protein_that_forms_a_complex_with_Lrs4p_which_binds_Mam1p_at_kinetochores_during_meiosis_I_to_mediate_accurate_chromosome_segregation,_may_be_involved_in_premeiotic_DNA_replication;_possible_role_in_telomere_maintenance" YCR087C-A None None biological_process_unknown molecular_function_unknown nucleolus None None 3 264464 264003 YCR087C-A S000007223 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleolus;_YCR087C-A_is_not_an_essential_gene YCR088W ABP1 None establishment_of_cell_polarity_(sensu_Fungi)* protein_binding cytoplasm* None None 3 265065 266843 YCR088W S000000684 "ORF,_Verified" "Actin-binding_protein_of_the_cortical_actin_cytoskeleton,_important_for_activation_of_the_Arp2/3_complex_that_plays_a_key_role_actin_in_cytoskeleton_organization" YCR089W FIG2 None cellular_morphogenesis_during_conjugation_with_cellular_fusion* molecular_function_unknown cell_wall_(sensu_Fungi) None None 3 267431 272260 YCR089W S000000685 "ORF,_Verified" "Cell_wall_adhesin,_expressed_specifically_during_mating;_may_be_involved_in_maintenance_of_cell_wall_integrity_during_mating" YCR090C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 3 272860 272312 YCR090C S000000686 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_YCR090C_is_not_an_essential_gene YCR092C MSH3 None DNA_recombination* damaged_DNA_binding nuclear_chromosome None None 3 279817 276761 YCR092C S000000688 "ORF,_Verified" "Mismatch_repair_protein,_forms_dimers_with_Msh2p_that_mediate_repair_of_insertion_or_deletion_mutations_and_removal_of_nonhomologous_DNA_ends,_contains_a_PCNA_(Pol30p)_binding_motif_required_for_genome_stability" YCR093W CDC39 SMD6|ROS1|NOT1 regulation_of_transcription_from_RNA_polymerase_II_promoter* 3'-5'-exoribonuclease_activity cytoplasm* None None 3 280114 286440 YCR093W S000000689 "ORF,_Verified" "Component_of_the_CCR4-NOT_complex,_which_has_multiple_roles_in_regulating_mRNA_levels_including_regulation_of_transcription_and_destabilizing_mRNAs_by_deadenylation;_basal_transcription_factor" YCR094W CDC50 None regulation_of_transcription* transcription_regulator_activity late_endosome* None None 3 286759 287934 YCR094W S000000690 "ORF,_Verified" "Endosomal_protein_that_regulates_cell_polarity,_controls_polarized_growth;_similar_to_Ynr048wp_and_Lem3p" YCR095C None None biological_process_unknown molecular_function_unknown cytoplasm None None 3 289255 288167 YCR095C S000000691 "ORF,_Uncharacterized" "Cytoplasmic_protein_required_for_replication_of_Brome_mosaic_virus_in_S._cerevisiae,_which_is_a_model_system_for_studying_replication_of_positive-strand_RNA_viruses_in_their_natural_hosts" YCR096C HMRA2 A2 biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 293535 293176 YCR096C S000000692 "ORF,_Verified|silenced_gene" Silenced_copy_of_a2_at_HMR;_similarity_to_Alpha2p;_required_along_with_a1p_for_inhibiting_expression_of_the_HO_endonuclease_in_a/alpha_HO/HO_diploid_cells_with_an_active_mating-type_interconversion_system YCR097W HMRA1 YCR097WB "regulation_of_transcription,_mating-type_specific" transcription_corepressor_activity nucleus None None 3 293832 294318 YCR097W S000000694 "ORF,_Verified|silenced_gene" Silenced_copy_of_a1_at_HMR;_homeobox_corepressor_that_interacts_with_Alpha2p_to_repress_haploid-specific_gene_transcription_in_diploid_cells YCR099C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 301296 300829 YCR099C S000000696 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YCR102C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 305464 304358 YCR102C S000000699 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_involved_in_copper_metabolism;_similar_to_C.carbonum_toxD_gene;_YCR102C_is_not_an_essential_gene YCR104W PAU3 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 3 307798 308172 YCR104W S000000701 "ORF,_Verified" "Part_of_23-member_seripauperin_multigene_family_encoded_mainly_in_subtelomeric_regions,_active_during_alcoholic_fermentation,_regulated_by_anaerobiosis,_negatively_regulated_by_oxygen,_repressed_by_heme" YCR106W RDS1 None response_to_xenobiotic_stimulus DNA_binding* nucleus None None 3 310955 313453 YCR106W S000000703 "ORF,_Verified" Zinc_cluster_transcription_factor_involved_in_conferring_resistance_to_cycloheximide YCR107W AAD3 None aldehyde_metabolism aryl-alcohol_dehydrogenase_activity cellular_component_unknown None None 3 313887 314978 YCR107W S000000704 "ORF,_Verified" Putative_aryl-alcohol_dehydrogenase_with_similarity_to_P._chrysosporium_aryl-alcohol_dehydrogenase;_mutational_analysis_has_not_yet_revealed_a_physiological_role YDL001W RMD1 None biological_process_unknown molecular_function_unknown cytoplasm None None 4 447982 449274 YDL001W S000002159 "ORF,_Verified" Cytoplasmic_protein_required_for_sporulation YDL003W MCD1 SCC1|RHC21|PDS3 mitotic_sister_chromatid_cohesion* molecular_function_unknown nucleus* G1 None 4 444681 446381 YDL003W S000002161 "ORF,_Verified" Essential_protein_required_for_sister_chromatid_cohesion_in_mitosis_and_meiosis;_subunit_of_the_cohesin_complex;_expression_is_cell_cycle_regulated_and_peaks_in_S_phase YDL004W ATP16 None ATP_synthesis_coupled_proton_transport "hydrogen-transporting_ATP_synthase_activity,_rotational_mechanism" "proton-transporting_ATP_synthase,_central_stalk_(sensu_Eukaryota)" None None 4 443027 443509 YDL004W S000002162 "ORF,_Verified" "Delta_subunit_of_the_central_stalk_of_mitochondrial_F1F0_ATP_synthase,_which_is_a_large,_evolutionarily_conserved_enzyme_complex_required_for_ATP_synthesis;_phosphorylated" YDL007W RPT2 YTA5|YHS4 ubiquitin-dependent_protein_catabolism ATPase_activity* nucleus* None None 4 438045 439358 YDL007W S000002165 "ORF,_Verified" One_of_six_ATPases_of_the_19S_regulatory_particle_of_the_26S_proteasome_involved_in_the_degradation_of_ubiquitinated_substrates;_required_for_normal_peptide_hydrolysis_by_the_core_20S_particle YDL010W GRX6 None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) G1 None 4 432328 433023 YDL010W S000002168 "ORF,_Verified" Cis-golgi_localized_monothiol_glutaredoxin_that_binds_an_iron-sulfur_cluster;_more_similar_in_activity_to_dithiol_than_other_monothiol_glutaredoxins;_involved_in_the_oxidative_stress_response;_functional_overlap_with_GRX7 YDL012C None None biological_process_unknown molecular_function_unknown plasma_membrane None None 4 431515 431106 YDL012C S000002170 "ORF,_Uncharacterized" Plasma_membrane_protein_of_unknown_function;_may_contribute_to_Non-homologous_end-joining_(NHEJ)_based_on_double_deletion_with_htz1;_YDL012C_is_not_an_essential_gene YDL013W SLX5 HEX3 sporulation_(sensu_Fungi)* DNA_binding nucleus None None 4 429065 430924 YDL013W S000002171 "ORF,_Verified" Subunit_of_the_Slx5-Slx8_substrate-specific_ubiquitin_ligase_complex;_stimulated_by_prior_attachment_of_SUMO_to_the_substrate YDL014W NOP1 LOT3 rRNA_modification* methyltransferase_activity nucleolus* None Down 4 427362 428345 YDL014W S000002172 "ORF,_Verified" "Nucleolar_protein,_component_of_the_small_subunit_processome_complex,_which_is_required_for_processing_of_pre-18S_rRNA;_has_similarity_to_mammalian_fibrillarin" YDL015C TSC13 None very-long-chain_fatty_acid_metabolism oxidoreductase_activity mitochondrion* None None 4 426932 426000 YDL015C S000002173 "ORF,_Verified" "Enoyl_reductase_that_catalyzes_the_last_step_in_each_cycle_of_very_long_chain_fatty_acid_elongation,_localizes_to_the_ER,_highly_enriched_in_a_structure_marking_nuclear-vacuolar_junctions,_coimmunoprecipitates_with_elongases_Fen1p_and_Sur4p" YDL018C ERP3 None secretory_pathway molecular_function_unknown integral_to_membrane G1 None 4 423508 422831 YDL018C S000002176 "ORF,_Verified" "Protein_with_similarity_to_Emp24p_and_Erv25p,_member_of_the_p24_family_involved_in_ER_to_Golgi_transport" YDL022W GPD1 OSR5|OSG1|HOR1|DAR1 intracellular_accumulation_of_glycerol glycerol-3-phosphate_dehydrogenase_(NAD+)_activity cytosol* None None 4 411823 412998 YDL022W S000002180 "ORF,_Verified" "NAD-dependent_glycerol-3-phosphate_dehydrogenase,_key_enzyme_of_glycerol_synthesis,_essential_for_growth_under_osmotic_stress;_expression_regulated_by_high-osmolarity_glycerol_response_pathway;_homolog_of_Gpd2p" YDL025C None None biological_process_unknown protein_kinase_activity cellular_component_unknown None Up 4 407204 405342 YDL025C S000002183 "ORF,_Uncharacterized" "Putative_protein_kinase,_potentially_phosphorylated_by_Cdc28p;_YDL025C_is_not_an_essential_gene" YDL027C None None biological_process_unknown molecular_function_unknown mitochondrion None None 4 404955 403693 YDL027C S000002185 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_YDL027C_is_not_an_essential_gene" YDL028C MPS1 RPK1 mitotic_spindle_checkpoint* protein_threonine/tyrosine_kinase_activity spindle_pole_body* None None 4 403289 400995 YDL028C S000002186 "ORF,_Verified" "Dual-specificity_kinase_required_for_spindle_pole_body_(SPB)_duplication_and_spindle_checkpoint_function;_substrates_include_SPB_proteins_Spc42p,_Spc110p,_and_Spc98p,_mitotic_exit_network_protein_Mob1p,_and_checkpoint_protein_Mad1p" YDL031W DBP10 None 35S_primary_transcript_processing* ATP-dependent_RNA_helicase_activity nucleolus None None 4 394215 397202 YDL031W S000002189 "ORF,_Verified" "Putative_ATP-dependent_RNA_helicase_of_the_DEAD-box_protein_family,_constituent_of_66S_pre-ribosomal_particles;_essential_protein_involved_in_ribosome_biogenesis" YDL033C SLM3 MTU1|MTO2 protein_biosynthesis* tRNA_(5-methylaminomethyl-2-thiouridylate)-methyltransferase_activity mitochondrion None None 4 393910 392657 YDL033C S000002191 "ORF,_Verified" "tRNA-specific_2-thiouridylase,_responsible_for_2-thiolation_of_the_wobble_base_of_mitochondrial_tRNAs;_human_ortholog_is_implicated_in_myoclonus_epilepsy_associated_with_ragged_red_fibers_(MERRF)" YDL036C PUS9 None tRNA_pseudouridine_synthesis tRNA-pseudouridine_synthase_activity cytoplasm* None None 4 388899 387511 YDL036C S000002194 "ORF,_Verified" Mitochondrial_tRNA_pseudouridine_synthase_involved_in_pseudouridylation_of_mitochondrial_tRNAs_at_position_32 YDL039C PRM7 YDL038C conjugation_with_cellular_fusion molecular_function_unknown integral_to_membrane G2/M Down 4 384079 381983 YDL038C S000002197 "ORF,_Verified" "Pheromone-regulated_protein,_predicted_to_have_one_transmembrane_segment;_promoter_contains_Gcn4p_binding_elements" YDL040C NAT1 AAA1 protein_amino_acid_acetylation peptide_alpha-N-acetyltransferase_activity cytoplasm* None None 4 381435 378871 YDL040C S000002198 "ORF,_Verified" "Subunit_of_the_N-terminal_acetyltransferase_NatA_(Nat1p,_Ard1p,_Nat5p);_N-terminally_acetylates_many_proteins,_which_influences_multiple_processes_such_as_the_cell_cycle,_heat-shock_resistance,_mating,_sporulation,_and_telomeric_silencing" YDL042C SIR2 MAR1_ chromatin_silencing_at_telomere* histone_deacetylase_activity* nucleolus* None None 4 378442 376754 YDL042C S000002200 "ORF,_Verified" "Conserved_NAD+_dependent_histone_deacetylase_of_the_Sirtuin_family_involved_in_regulation_of_lifespan;_plays_roles_in_silencing_at_HML,_HMR,_telomeres,_and_the_rDNA_locus;_negatively_regulates_initiation_of_DNA_replication" YDL043C PRP11 RNA11 spliceosome_assembly RNA_binding snRNP_U2 None None 4 376477 375677 YDL043C S000002201 "ORF,_Verified" "Subunit_of_the_SF3a_splicing_factor_complex,_required_for_spliceosome_assembly" YDL045C FAD1 None FAD_biosynthesis FMN_adenylyltransferase_activity cytoplasm None None 4 373605 372685 YDL045C S000002203 "ORF,_Verified" "Flavin_adenine_dinucleotide_(FAD)_synthetase,_performs_the_second_step_in_synthesis_of_FAD_from_riboflavin" YDL045W-A MRP10 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 4 372245 372532 YDL045W-A S000006430 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YDL046W NPC2 None sterol_transport molecular_function_unknown vacuole_(sensu_Fungi)* None None 4 371237 371758 YDL046W S000002204 "ORF,_Verified" "Functional_homolog_of_human_NPC2/He1,_which_is_a_cholesterol-binding_protein_whose_deficiency_causes_Niemann-Pick_type_C2_disease_involving_retention_of_cholesterol_in_lysosomes" YDL048C STP4 None biological_process_unknown molecular_function_unknown cytoplasm* G2/M None 4 368211 366739 YDL048C S000002206 "ORF,_Verified" "Protein_containing_a_Kruppel-type_zinc-finger_domain;_has_similarity_to_Stp1p,_Stp2p,_and_Stp3p" YDL049C KNH1 None "beta-1,6_glucan_biosynthesis" molecular_function_unknown cell_wall_(sensu_Fungi)* None None 4 365874 365068 YDL049C S000002207 "ORF,_Verified" "Protein_with_similarity_to_Kre9p,_which_is_involved_in_cell_wall_beta_1,6-glucan_synthesis;_overproduction_suppresses_growth_defects_of_a_kre9_null_mutant" YDL051W LHP1 YLA1|LAH1 tRNA_processing RNA_binding nucleus* None Down 4 363952 364779 YDL051W S000002209 "ORF,_Verified" RNA_binding_protein_required_for_maturation_of_tRNA_and_U6_snRNA_precursors;_acts_as_a_molecular_chaperone_for_RNAs_transcribed_by_polymerase_III;_homologous_to_human_La_(SS-B)_autoantigen YDL052C SLC1 None sphingolipid_biosynthesis 1-acylglycerol-3-phosphate_O-acyltransferase_activity lipid_particle None None 4 363583 362672 YDL052C S000002210 "ORF,_Verified" "1-acyl-sn-gylcerol-3-phosphate_acyltransferase,_catalyzes_the_acylation_of_lysophosphatidic_acid_to_form_phosphatidic_acid,_a_key_intermediate_in_lipid_metabolism;_enzymatic_activity_detected_in_lipid_particles_and_microsomes" YDL061C RPS29B YS29B protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 4 340798 340628 YDL061C S000002219 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps29Ap_and_has_similarity_to_rat_S29_and_E._coli_S14_ribosomal_proteins YDL063C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 340134 338272 YDL063C S000002221 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_YDL063C_is_not_an_essential_gene YDL064W UBC9 None G2/M_transition_of_mitotic_cell_cycle* SUMO_conjugating_enzyme_activity nucleus None None 4 337487 338070 YDL064W S000002222 "ORF,_Verified" SUMO-conjugating_enzyme_involved_in_the_Smt3p_conjugation_pathway;_nuclear_protein_required_for_S-_and_M-phase_cyclin_degradation_and_mitotic_control;_involved_in_proteolysis_mediated_by_the_anaphase-promoting_complex_cyclosome_(APCC) YDL065C PEX19 PAS12 protein_folding* protein_binding cytosol None None 4 337277 336249 YDL065C S000002223 "ORF,_Verified" "Chaperone_and_import_receptor_for_newly-synthesized_class_I_peroxisomal_membrane_proteins_(PMPs),_binds_PMPs_in_the_cytoplasm_and_delivers_them_to_the_peroxisome_for_subsequent_insertion_into_the_peroxisomal_membrane" YDL067C COX9 None aerobic_respiration* cytochrome-c_oxidase_activity respiratory_chain_complex_IV_(sensu_Eukaryota) None None 4 334396 334217 YDL067C S000002225 "ORF,_Verified" "Subunit_VIIa_of_cytochrome_c_oxidase,_which_is_the_terminal_member_of_the_mitochondrial_inner_membrane_electron_transport_chain" YDL070W BDF2 None biological_process_unknown molecular_function_unknown nucleus None None 4 331025 332941 YDL070W S000002228 "ORF,_Verified" Protein_involved_in_transcription_initiation_at_TATA-containing_promoters;_associates_with_the_basal_transcription_factor_TFIID;_contains_two_bromodomains;_corresponds_to_the_C-terminal_region_of_mammalian_TAF1;_redundant_with_Bdf1p YDL073W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 326613 329567 YDL073W S000002231 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YDL073W_is_not_an_essential_gene YDL074C BRE1 None chromatin_silencing_at_telomere* ubiquitin-protein_ligase_activity nucleus None None 4 326149 324047 YDL074C S000002232 "ORF,_Verified" "E3_ubiquitin_ligase_for_Rad6p,_required_for_the_ubiquitination_of_histone_H2B,_recruitment_of_Rad6p_to_promoter_chromatin_and_subsequent_methylation_of_histone_H3_(on_K4_and_K79),_contains_RING_finger_domain" YDL075W RPL31A RPL34 protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 4 322226 322988 YDL075W S000002233 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl31Bp_and_has_similarity_to_rat_L31_ribosomal_protein;_associates_with_the_karyopherin_Sxm1p" YDL077C VAM6 VPS39|VPL22|VPL18|CVT4 "homotypic_vacuole_fusion,_non-autophagic*" Rab_guanyl-nucleotide_exchange_factor_activity vacuole_(sensu_Fungi)* None None 4 320120 316971 YDL077C S000002235 "ORF,_Verified" Vacuolar_protein_that_plays_a_critical_role_in_the_tethering_steps_of_vacuolar_membrane_fusion_by_facilitating_guanine_nucleotide_exchange_on_small_guanosine_triphosphatase_Ypt7p YDL078C MDH3 None fatty_acid_beta-oxidation* L-malate_dehydrogenase_activity peroxisome* None None 4 316388 315357 YDL078C S000002236 "ORF,_Verified" "Peroxisomal_malate_dehydrogenase,_catalyzes_interconversion_of_malate_and_oxaloacetate;_involved_in_the_glyoxylate_cycle" YDL080C THI3 KID1 thiamin_biosynthesis transcriptional_activator_activity* nucleus None None 4 312471 310642 YDL080C S000002238 "ORF,_Verified" "Probable_alpha-ketoisocaproate_decarboxylase,_may_have_a_role_in_catabolism_of_amino_acids_to_long-chain_and_complex_alcohols;_required_for_expression_of_enzymes_involved_in_thiamine_biosynthesis" YDL081C RPP1A RPLA1 translational_elongation* structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 4 310122 309802 YDL081C S000002239 "ORF,_Verified" "Ribosomal_stalk_protein_P1_alpha,_involved_in_the_interaction_between_translational_elongation_factors_and_the_ribosome;_accumulation_of_P1_in_the_cytoplasm_is_regulated_by_phosphorylation_and_interaction_with_the_P2_stalk_component" YDL082W RPL13A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 4 308424 309388 YDL082W S000002240 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl13Bp;_not_essential_for_viability;_has_similarity_to_rat_L13_ribosomal_protein" YDL083C RPS16B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 4 307789 306926 YDL083C S000002241 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_identical_to_Rps16Ap_and_has_similarity_to_E._coli_S9_and_rat_S16_ribosomal_proteins YDL084W SUB2 None "nuclear_mRNA_splicing,_via_spliceosome*" protein_binding* nucleus* None None 4 305237 306577 YDL084W S000002242 "ORF,_Verified" Component_of_the_TREX_complex_required_for_nuclear_mRNA_export;_member_of_the_DEAD-box_RNA_helicase_superfamily_and_is_involved_in_early_and_late_steps_of_spliceosome_assembly;_homolog_of_the_human_splicing_factor_hUAP56 YDL086W None None biological_process_unknown carboxymethylenebutenolidase_activity cytoplasm* None None 4 301413 302234 YDL086W S000002244 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_YDL086W_is_not_an_essential_gene" YDL091C UBX3 None biological_process_unknown molecular_function_unknown cytoplasm None None 4 294759 293392 YDL091C S000002249 "ORF,_Verified" "UBX_(ubiquitin_regulatory_X)_domain-containing_protein_that_interacts_with_Cdc48p,_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern" YDL092W SRP14 None protein_targeting_to_ER* signal_sequence_binding signal_recognition_particle_(sensu_Eukaryota) None None 4 292781 293221 YDL092W S000002250 "ORF,_Verified" "Signal_recognition_particle_(SRP)_subunit,_interacts_with_the_RNA_component_of_SRP_to_form_the_Alu_domain,_which_is_the_region_of_SRP_responsible_for_arrest_of_nascent_chain_elongation_during_membrane_targeting;_homolog_of_mammalian_SRP14" YDL095W PMT1 None protein_amino_acid_O-linked_glycosylation dolichyl-phosphate-mannose-protein_mannosyltransferase_activity endoplasmic_reticulum_membrane G1 None 4 287059 289512 YDL095W S000002253 "ORF,_Verified" "Protein_O-mannosyltransferase,_transfers_mannose_residues_from_dolichyl_phosphate-D-mannose_to_protein_serine/threonine_residues;_acts_in_a_complex_with_Pmt2p,_can_instead_interact_with_Pmt3p_in_some_conditions;_target_for_new_antifungals" YDL097C RPN6 NAS4 ubiquitin-dependent_protein_catabolism structural_molecule_activity "proteasome_regulatory_particle,_lid_subcomplex_(sensu_Eukaryota)" None None 4 286695 285391 YDL097C S000002255 "ORF,_Verified" "Essential,_non-ATPase_regulatory_subunit_of_the_26S_proteasome_lid_required_for_the_assembly_and_activity_of_the_26S_proteasome;_the_human_homolog_(S9_protein)_partially_rescues_Rpn6p_depletion" YDL099W BUG1 None ER_to_Golgi_transport molecular_function_unknown cytoplasm None None 4 283419 284444 YDL099W S000002257 "ORF,_Verified" "Cis-golgi_localized_protein_involved_in_ER_to_Golgi_transport;_forms_a_complex_with_the_mammalian_GRASP65_homolog,_Grh1p;_mutants_are_compromised_for_the_fusion_of_ER-derived_vesicles_with_Golgi_membranes" YDL100C GET3 ARR4 "retrograde_transport,_Golgi_to_ER*" ATPase_activity endoplasmic_reticulum* None None 4 283176 282112 YDL100C S000002258 "ORF,_Verified" "Guanine_nucleotide_exchange_factor_for_Gpa1p;_amplifies_G_protein_signaling;_subunit_of_the_GET_complex,_which_is_involved_in_Golgi_to_ER_trafficking;_has_low-level_ATPase_activity_and_is_involved_in_resistance_to_heat_and_metal_stress" YDL101C DUN1 None protein_amino_acid_phosphorylation* protein_kinase_activity nucleus G1 Up 4 281848 280307 YDL101C S000002259 "ORF,_Verified" "Cell-cycle_checkpoint_serine-threonine_kinase_required_for_DNA_damage-induced_transcription_of_certain_target_genes,_phosphorylation_of_Rad55p_and_Sml1p,_and_transient_G2/M_arrest_after_DNA_damage;_also_regulates_postreplicative_DNA_repair" YDL103C QRI1 UAP1 UDP-N-acetylglucosamine_biosynthesis UDP-N-acetylglucosamine_diphosphorylase_activity cytoplasm* G1 None 4 276581 275148 YDL103C S000002261 "ORF,_Verified" "UDP-N-acetylglucosamine_pyrophosphorylase,_catalyzes_the_formation_of_UDP-N-acetylglucosamine_(UDP-GlcNAc),_which_is_important_in_cell_wall_biosynthesis,_protein_N-glycosylation,_and_GPI_anchor_biosynthesis" YDL104C QRI7 None proteolysis metalloendopeptidase_activity mitochondrion None None 4 274876 273653 YDL104C S000002262 "ORF,_Uncharacterized" "Putative_metalloprotease,_similar_to_O-sialoglycoprotein_metallopeptidase_from_P._haemolytica;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YDL105W NSE4 QRI2 DNA_repair molecular_function_unknown nucleus* G1 None 4 272389 273597 YDL105W S000002263 "ORF,_Verified" Nuclear_protein_that_plays_a_role_in_the_function_of_the_Smc5p-Rhc18p_complex YDL110C TMA17 None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 264964 264512 YDL110C S000002268 "ORF,_Verified" Protein_of_unknown_function_that_associates_with_ribosomes;_heterozygous_deletion_demonstrated_increases_in_chromosome_instability_in_a_rad9_deletion_background YDL111C RRP42 None 35S_primary_transcript_processing* 3'-5'-exoribonuclease_activity nuclear_exosome_(RNase_complex)* None None 4 264110 263313 YDL111C S000002269 "ORF,_Verified" "Protein_involved_in_rRNA_processing;_component_of_the_exosome_3->5_exonuclease_complex_with_Rrp4p,_Rrp41p,_Rrp43p_and_Dis3p" YDL112W TRM3 None tRNA_methylation tRNA_(guanosine)_methyltransferase_activity cytoplasm None None 4 258915 263225 YDL112W S000002270 "ORF,_Verified" "2'-O-ribose_methyltransferase,_catalyzes_the_ribose_methylation_of_the_guanosine_nucleotide_at_position_18_of_tRNAs" YDL113C ATG20 CVT20|SNX42 protein_targeting_to_vacuole* lipid_binding membrane None None 4 258555 256633 YDL113C S000002271 "ORF,_Verified" Sorting_nexin_family_member_required_for_the_cytoplasm-to-vacuole_targeting_(Cvt)_pathway_and_for_endosomal_sorting;_has_a_Phox_homology_domain_that_binds_phosphatidylinositol-3-phosphate;_interacts_with_Snx4p;_potential_Cdc28p_substrate YDL120W YFH1 None iron_ion_homeostasis* enzyme_regulator_activity mitochondrion* None None 4 245923 246447 YDL120W S000002278 "ORF,_Verified" "Frataxin,_regulates_mitochondrial_iron_accumulation;_interacts_with_Isu1p_which_promotes_Fe-S_cluster_assembly;_interacts_with_electron_transport_chain_components_and_may_influence_respiration;_human_homolog_involved_in_Friedrich's_ataxia" YDL121C None None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 4 245582 245133 YDL121C S000002279 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_endoplasmic_retiuculum;_YDL121C_is_not_an_essential_protein YDL122W UBP1 None protein_deubiquitination ubiquitin-specific_protease_activity cytoplasm* None None 4 242552 244981 YDL122W S000002280 "ORF,_Verified" Ubiquitin-specific_protease_that_removes_ubiquitin_from_ubiquitinated_proteins;_cleaves_at_the_C_terminus_of_ubiquitin_fusions_irrespective_of_their_size;_capable_of_cleaving_polyubiquitin_chains YDL123W SNA4 None biological_process_unknown molecular_function_unknown vacuolar_membrane_(sensu_Fungi) None None 4 241418 241840 YDL123W S000002281 "ORF,_Verified" "Protein_of_unknown_function,_localized_to_the_vacuolar_outer_membrane" YDL124W None None metabolism alpha-keto_amide_reductase_activity* cytoplasm* None None 4 240259 241197 YDL124W S000002282 "ORF,_Verified" "NADPH-dependent_alpha-keto_amide_reductase;_reduces_aromatic_alpha-keto_amides,_aliphatic_alpha-keto_esters,_and_aromatic_alpha-keto_esters;_member_of_the_aldo-keto_reductase_(AKR)_family" YDL125C HNT1 None nucleotide_metabolism hydrolase_activity* cytoplasm* None None 4 239606 239019 YDL125C S000002283 "ORF,_Verified" "Adenosine_5'-monophosphoramidase;_interacts_physically_and_genetically_with_Kin28p,_a_CDK_and_TFIIK_subunit,_and_genetically_with_CAK1;_member_of_the_histidine_triad_(HIT)_superfamily_of_nucleotide-binding_proteins_and_similar_to_Hint" YDL126C CDC48 None ubiquitin-dependent_protein_catabolism* ATPase_activity nucleus* None None 4 238664 236157 YDL126C S000002284 "ORF,_Verified" "ATPase_in_ER,_nuclear_membrane_and_cytosol_with_homology_to_mammalian_p97;_in_a_complex_with_Npl4p_and_Ufd1p_participates_in_retrotranslocation_of_ubiquitinated_proteins_from_the_ER_into_the_cytosol_for_degradation_by_the_proteasome" YDL127W PCL2 CLN4 cell_cycle cyclin-dependent_protein_kinase_regulator_activity cyclin-dependent_protein_kinase_holoenzyme_complex M/G1 None 4 234927 235853 YDL127W S000002285 "ORF,_Verified" "G1_cyclin,_associates_with_Pho85p_cyclin-dependent_kinase_(Cdk)_to_contribute_to_entry_into_the_mitotic_cell_cycle,_essential_for_cell_morphogenesis;_localizes_to_sites_of_polarized_cell_growth" YDL128W VCX1 MNR1|HUM1 calcium_ion_homeostasis* calcium_ion_transporter_activity* vacuole_(sensu_Fungi)* G2/M None 4 232652 233887 YDL128W S000002286 "ORF,_Verified" "Vacuolar_H+/Ca2+_exchanger_involved_in_control_of_cytosolic_Ca2+_concentration;_has_similarity_to_sodium/calcium_exchangers,_including_the_bovine_Na+/Ca2+,K+_antiporter" YDL129W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 231024 231899 YDL129W S000002287 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_the_nucleus;_YDL129W_is_not_an_essential_gene YDL130W RPP1B RPLA3|RPL44' translational_elongation* structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None Down 4 229906 230527 YDL130W S000002288 "ORF,_Verified" "Ribosomal_protein_P1_beta,_component_of_the_ribosomal_stalk,_which_is_involved_in_interaction_of_translational_elongation_factors_with_ribosome;_accumulation_is_regulated_by_phosphorylation_and_interaction_with_the_P2_stalk_component" YDL130W-A STF1 AIS2 ATP_synthesis_coupled_proton_transport molecular_function_unknown proton-transporting_ATP_synthase_complex_(sensu_Eukaryota) None None 4 229171 229431 YDL130W-A S000007232 "ORF,_Verified" Protein_involved_in_regulation_of_the_mitochondrial_F1F0-ATP_synthase;_Stf1p_and_Stf2p_may_act_as_stabilizing_factors_that_enhance_inhibitory_action_of_the_Inh1p_protein YDL131W LYS21 None lysine_biosynthesis_via_aminoadipic_acid homocitrate_synthase_activity nucleus None None 4 227393 228715 YDL131W S000002289 "ORF,_Verified" "Homocitrate_synthase_isozyme,_catalyzes_the_condensation_of_acetyl-CoA_and_alpha-ketoglutarate_to_form_homocitrate,_which_is_the_first_step_in_the_lysine_biosynthesis_pathway;_highly_similar_to_the_other_isozyme,_Lys20p" YDL133C-A RPL41B YDL134C-A|RPL47B protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 4 221801 221724 YDL133C-A S000002293 "ORF,_Verified" "Ribosomal_protein_L47_of_the_large_(60S)_ribosomal_subunit,_identical_to_Rpl41Ap_and_has_similarity_to_rat_L41_ribosomal_protein;_comprised_of_only_25_amino_acids;_rpl41a_rpl41b_double_null_mutant_is_viable" YDL134C PPH21 PPH1 protein_biosynthesis* protein_phosphatase_type_2A_activity protein_phosphatase_type_2A_complex None None 4 220771 219662 YDL134C S000002292 "ORF,_Verified" "Catalytic_subunit_of_protein_phosphatase_2A,_functionally_redundant_with_Pph22p;_methylated_at_C_terminus;_forms_alternate_complexes_with_several_regulatory_subunits;_involved_in_signal_transduction_and_regulation_of_mitosis" YDL135C RDI1 None actin_filament_organization* signal_transducer_activity* cytosol None None 4 219288 218680 YDL135C S000002294 "ORF,_Verified" Rho_GDP_dissociation_inhibitor_involved_in_the_localization_and_regulation_of_Cdc42p YDL136W RPL35B SOS2 protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 4 217600 218367 YDL136W S000002295 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_identical_to_Rpl35Ap_and_has_similarity_to_rat_L35_ribosomal_protein" YDL137W ARF2 None ER_to_Golgi_transport* GTPase_activity cytosol* None None 4 216529 217074 YDL137W S000002296 "ORF,_Verified" "ADP-ribosylation_factor,_GTPase_of_the_Ras_superfamily_involved_in_regulation_of_coated_formation_vesicles_in_intracellular_trafficking_within_the_Golgi;_functionally_interchangeable_with_Arf1p" YDL141W BPL1 ACC2 protein_amino_acid_biotinylation biotin-[acetyl-CoA-carboxylase]_ligase_activity* cytoplasm* None None 4 203040 205112 YDL141W S000002300 "ORF,_Verified" "Biotin:apoprotein_ligase,_covalently_modifies_proteins_with_the_addition_of_biotin,_required_for_acetyl-CoA_carboxylase_(Acc1p)_holoenzyme_formation" YDL142C CRD1 CLS1 mitochondrial_membrane_organization_and_biogenesis* cardiolipin_synthase_activity mitochondrial_envelope None None 4 202571 201720 YDL142C S000002301 "ORF,_Verified" "Cardiolipin_synthase;_produces_cardiolipin,_which_is_an_important_constituent_of_mitochondrial_membranes;_required_for_normal_mitochondrial_membrane_potential_and_function" YDL143W CCT4 ANC2|TCP4 protein_folding* unfolded_protein_binding cytoplasm* None None 4 199997 201583 YDL143W S000002302 "ORF,_Verified" "Subunit_of_the_cytosolic_chaperonin_Cct_ring_complex,_related_to_Tcp1p,_required_for_the_assembly_of_actin_and_tubulins_in_vivo" YDL144C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 199733 198663 YDL144C S000002303 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_YDL144C_is_not_an_essential_gene. YDL145C COP1 SOO1|RET1|SEC33 ER_to_Golgi_transport* molecular_function_unknown COPI_vesicle_coat None None 4 198177 194572 YDL145C S000002304 "ORF,_Verified" "Alpha_subunit_of_COPI_vesicle_coatomer_complex,_which_surrounds_transport_vesicles_in_the_early_secretory_pathway" YDL147W RPN5 NAS5 ubiquitin-dependent_protein_catabolism molecular_function_unknown "proteasome_regulatory_particle,_lid_subcomplex_(sensu_Eukaryota)" None None 4 190925 192262 YDL147W S000002306 "ORF,_Verified" "Essential,_non-ATPase_regulatory_subunit_of_the_26S_proteasome_lid,_similar_to_mammalian_p55_subunit_and_to_another_S._cerevisiae_regulatory_subunit,_Rpn7p" YDL148C NOP14 UTP2 processing_of_20S_pre-rRNA snoRNA_binding mitochondrion* None None 4 190587 188155 YDL148C S000002307 "ORF,_Verified" "Nucleolar_protein,_forms_a_complex_with_Noc4p_that_mediates_maturation_and_nuclear_export_of_40S_ribosomal_subunits;_also_present_in_the_small_subunit_processome_complex,_which_is_required_for_processing_of_pre-18S_rRNA" YDL153C SAS10 UTP3 processing_of_20S_pre-rRNA* snoRNA_binding nucleus* None None 4 183019 181187 YDL153C S000002312 "ORF,_Verified" "Component_of_the_small_(ribosomal)_subunit_(SSU)_processosome_required_for_pre-18S_rRNa_processing;_essential_nucleolar_protein_that,_when_overproduced,_disrupts_silencing" YDL167C NRP1 None biological_process_unknown molecular_function_unknown cytoplasm None None 4 163155 160996 YDL167C S000002326 "ORF,_Verified" "Protein_of_unknown_function,_rich_in_asparagine_residues" YDL168W SFA1 ADH5 formaldehyde_catabolism alcohol_dehydrogenase_activity* cytoplasm* None None 4 159605 160765 YDL168W S000002327 "ORF,_Verified" "Bifunctional_enzyme_containing_both_alcohol_dehydrogenase_and_glutathione-dependent_formaldehyde_dehydrogenase_activities,_functions_in_formaldehyde_detoxification_and_formation_of_long_chain_and_complex_alcohols,_regulated_by_Hog1p-Sko1p" YDL170W UGA3 None regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_factor_activity* nucleus None None 4 156319 157905 YDL170W S000002329 "ORF,_Verified" "Transcriptional_activator_necessary_for_gamma-aminobutyrate_(GABA)-dependent_induction_of_GABA_genes_(such_as_UGA1,_UGA2,_UGA4);_zinc-finger_transcription_factor_of_the_Zn(2)-Cys(6)_binuclear_cluster_domain_type;_localized_to_the_nucleus" YDL171C GLT1 None glutamate_biosynthesis glutamate_synthase_(NADH)_activity mitochondrion* None None 4 155641 149204 YDL171C S000002330 "ORF,_Verified" "NAD(+)-dependent_glutamate_synthase_(GOGAT),_synthesizes_glutamate_from_glutamine_and_alpha-ketoglutarate;_with_Gln1p,_forms_the_secondary_pathway_for_glutamate_biosynthesis_from_ammonia;_expression_regulated_by_nitrogen_source" YDL177C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 141722 141210 YDL177C S000002336 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_similar_to_the_mouse_IMPACT_gene;_YDL177C_is_not_an_essential_gene YDL180W None None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) G2/M None 4 135897 137540 YDL180W S000002339 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuole YDL182W LYS20 None lysine_biosynthesis_via_aminoadipic_acid homocitrate_synthase_activity nucleus* None None 4 133438 134724 YDL182W S000002341 "ORF,_Verified" "Homocitrate_synthase_isozyme,_catalyzes_the_condensation_of_acetyl-CoA_and_alpha-ketoglutarate_to_form_homocitrate,_which_is_the_first_step_in_the_lysine_biosynthesis_pathway;_highly_similar_to_the_other_isozyme,_Lys21p" YDL184C RPL41A RPL47A protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 4 130485 130408 YDL184C S000002343 "ORF,_Verified" "Ribosomal_protein_L47_of_the_large_(60S)_ribosomal_subunit,_identical_to_Rpl41Bp_and_has_similarity_to_rat_L41_ribosomal_protein;_comprised_of_only_25_amino_acids;_rpl41a_rpl41b_double_null_mutant_is_viable" YDL189W RBS1 None galactose_metabolism molecular_function_unknown cytoplasm None None 4 122217 123590 YDL189W S000002348 "ORF,_Verified" "Protein_of_unknown_function,_identified_as_a_high_copy_suppressor_of_psk1_psk2_mutations_that_confer_temperature-sensitivity_for_galactose_utilization;_proposed_to_bind_single-stranded_nucleic_acids_via_its_R3H_domain" YDL191W RPL35A SOS1 protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 4 117665 118518 YDL191W S000002350 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_identical_to_Rpl35Bp_and_has_similarity_to_rat_L35_ribosomal_protein" YDL192W ARF1 None ER_to_Golgi_transport* GTPase_activity cytosol* None None 4 116322 116867 YDL192W S000002351 "ORF,_Verified" "ADP-ribosylation_factor,_GTPase_of_the_Ras_superfamily_involved_in_regulation_of_coated_vesicle_formation_in_intracellular_trafficking_within_the_Golgi;_functionally_interchangeable_with_Arf2p" YDL193W NUS1 None biological_process_unknown prenyltransferase_activity endoplasmic_reticulum* None None 4 114673 115800 YDL193W S000002352 "ORF,_Verified" "Putative_prenyltransferase,_required_for_cell_viability;_proposed_to_be_involved_in_protein_trafficking_because_tet-repressible_mutant_shows_accumulation_of_hypoglycosylated_forms_of_CPY" YDL200C MGT1 MGMT DNA_dealkylation methylated-DNA-[protein]-cysteine_S-methyltransferase_activity nucleus None None 4 101068 100502 YDL200C S000002359 "ORF,_Verified" DNA_repair_methyltransferase_(6-O-methylguanine-DNA_methylase)_involved_in_protection_against_DNA_alkylation_damage YDL201W TRM8 None tRNA_methylation protein_binding* nucleus None None 4 99562 100422 YDL201W S000002360 "ORF,_Verified" Subunit_of_a_tRNA_methyltransferase_complex_composed_of_Trm8p_and_Trm82p_that_catalyzes_7-methylguanosine_modification_of_tRNA YDL202W MRPL11 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 4 98476 99225 YDL202W S000002361 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YDL212W SHR3 APF1 ER_to_Golgi_transport* unfolded_protein_binding integral_to_endoplasmic_reticulum_membrane None None 4 78427 79059 YDL212W S000002371 "ORF,_Verified" "Endoplasmic_reticulum_packaging_chaperone,_required_for_incorporation_of_amino_acid_permeases_into_COPII_coated_vesicles_for_transport_to_the_cell_surface" YDL213C NOP6 None rRNA_processing* molecular_function_unknown nucleolus None Down 4 77967 77290 YDL213C S000002372 "ORF,_Verified" Putative_RNA-binding_protein_implicated_in_ribosome_biogenesis;_contains_an_RNA_recognition_motif_(RRM)_and_has_similarity_to_hydrophilins;_NOP6_may_be_a_fungal-specific_gene_as_no_homologs_have_been_yet_identified_in_higher_eukaryotes YDL215C GDH2 GDHB|GDH-B nitrogen_compound_metabolism glutamate_dehydrogenase_activity mitochondrion* None Up 4 73919 70641 YDL215C S000002374 "ORF,_Verified" "NAD(+)-dependent_glutamate_dehydrogenase,_degrades_glutamate_to_ammonia_and_alpha-ketoglutarate;_expression_sensitive_to_nitrogen_catabolite_repression_and_intracellular_ammonia_levels" YDL217C TIM22 None protein_import_into_mitochondrial_inner_membrane protein_transporter_activity mitochondrial_inner_membrane_protein_insertion_complex None None 4 68607 67984 YDL217C S000002376 "ORF,_Verified" Component_of_the_mitochondrial_Tim54p-Tim22p_complex_involved_in_insertion_of_polytopic_proteins_into_the_inner_membrane YDL224C WHI4 None regulation_of_cell_size RNA_binding cytoplasm None None 4 56347 54398 YDL224C S000002383 "ORF,_Verified" Putative_RNA_binding_protein_and_partially_redundant_Whi3p_homolog_that_regulates_the_cell_size_requirement_for_passage_through_Start_and_commitment_to_cell_division YDL225W SHS1 SEP7_ establishment_of_cell_polarity_(sensu_Fungi)* structural_constituent_of_cytoskeleton septin_ring None None 4 52446 54101 YDL225W S000002384 "ORF,_Verified" "One_of_five_related_septins_(Cdc3p,_Cdc10p,_Cdc11p,_Cdc12p,_Shs1p)_that_form_a_cortical_filamentous_collar_at_the_mother-bud_neck_which_is_necessary_for_normal_morphogenesis_and_cytokinesis" YDL227C HO None mating_type_switching* endonuclease_activity nucleus G1 None 4 48032 46272 YDL227C S000002386 "ORF,_Verified" "Site-specific_endonuclease_required_for_gene_conversion_at_the_MAT_locus_(homothallic_switching)_through_the_generation_of_a_ds_DNA_break;_expression_restricted_to_mother_cells_in_late_G1_as_controlled_by_Swi4p-Swi6p,_Swi5p_and_Ash1p" YDL229W SSB1 YG101 protein_biosynthesis ATPase_activity* soluble_fraction* None None 4 44066 45907 YDL229W S000002388 "ORF,_Verified" "Cytoplasmic_ATPase_that_is_a_ribosome-associated_molecular_chaperone,_functions_with_J-protein_partner_Zuo1p;_may_be_involved_in_folding_of_newly-made_polypeptide_chains;_member_of_the_HSP70_family;_interacts_with_phosphatase_subunit_Reg1p" YDL231C BRE4 None endocytosis molecular_function_unknown integral_to_membrane None None 4 42245 38868 YDL231C S000002390 "ORF,_Verified" "Zinc_finger_protein_containing_five_transmembrane_domains;_null_mutant_exhibits_strongly_fragmented_vacuoles_and_sensitivity_to_brefeldin_A,_a_drug_which_is_known_to_affect_intracellular_transport" YDL232W OST4 None protein_amino_acid_N-linked_glycosylation "protein_binding,_bridging*" endoplasmic_reticulum_membrane* None None 4 38488 38598 YDL232W S000002391 "ORF,_Verified" "Subunit_of_the_oligosaccharyltransferase_complex_of_the_ER_lumen,_which_catalyzes_protein_asparagine-linked_glycosylation;_type_I_membrane_protein_required_for_incorporation_of_Ost3p_or_Ost6p_into_the_OST_complex" YDL233W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 36798 38174 YDL233W S000002392 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_YDL233W_is_not_an_essential_gene YDL234C GYP7 None vesicle-mediated_transport Rab_GTPase_activator_activity cytoplasm None None 4 36478 34238 YDL234C S000002393 "ORF,_Verified" "GTPase-activating_protein_for_yeast_Rab_family_members_including:_Ypt7p_(most_effective),_Ypt1p,_Ypt31p,_and_Ypt32p_(in_vitro);_involved_in_vesicle_mediated_protein_trafficking" YDL235C YPD1 None response_to_osmotic_stress* "transferase_activity,_transferring_phosphorus-containing_groups" cytoplasm None None 4 33918 33415 YDL235C S000002394 "ORF,_Verified" "Phosphorelay_intermediate_protein,_phosphorylated_by_the_plasma_membrane_sensor_Sln1p_in_response_to_osmotic_stress_and_then_in_turn_phosphorylates_the_response_regulators_Ssk1p_in_the_cytosol_and_Skn7p_in_the_nucleus" YDL237W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 30657 31829 YDL237W S000002396 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YDL237W_is_not_an_essential_gene;_null_mutant_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation)_and_severe_growth_defect_in_minimal_glycerol_media YDL241W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 20635 21006 YDL241W S000002400 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YDL241W_is_not_an_essential_gene YDL243C AAD4 None aldehyde_metabolism aryl-alcohol_dehydrogenase_activity cellular_component_unknown None Up 4 18566 17577 YDL243C S000002402 "ORF,_Verified" "Putative_aryl-alcohol_dehydrogenase_with_similarity_to_P._chrysosporium_aryl-alcohol_dehydrogenase,_involved_in_the_oxidative_stress_response" YDR003W RCR2 SSH5 biological_process_unknown molecular_function_unknown cytoplasm* None Up 4 454120 454752 YDR003W S000002410 "ORF,_Verified" "Vacuolar_protein_that_presumably_functions_within_the_endosomal-vacuolar_trafficking_pathway,_affecting_events_that_determine_whether_plasma_membrane_proteins_are_degraded_or_routed_to_the_plasma_membrane;_similar_to_Rcr1p" YDR009W GAL3 None "regulation_of_transcription,_DNA-dependent*" protein_binding cytoplasm None None 4 463432 464994 YDR009W S000002416 "ORF,_Verified" Transcriptional_regulator_involved_in_activation_of_the_GAL_genes_in_response_to_galactose;_forms_a_complex_with_Gal80p_to_relieve_Gal80p_inhibition_of_Gal4p;_binds_galactose_and_ATP_but_does_not_have_galactokinase_activity YDR012W RPL4B None protein_biosynthesis structural_constituent_of_ribosome cytoplasm* None None 4 471851 472939 YDR012W S000002419 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl4Ap_and_has_similarity_to_E._coli_L4_and_rat_L4_ribosomal_proteins" YDR013W PSF1 CDC101 DNA-dependent_DNA_replication molecular_function_unknown GINS_complex None None 4 473155 473781 YDR013W S000002420 "ORF,_Verified" "Subunit_of_the_GINS_complex_(Sld5p,_Psf1p,_Psf2p,_Psf3p),_which_is_localized_to_DNA_replication_origins_and_implicated_in_assembly_of_the_DNA_replication_machinery" YDR019C GCV1 GSD1 one-carbon_compound_metabolism* glycine_dehydrogenase_(decarboxylating)_activity mitochondrion* None Up 4 485363 484161 YDR019C S000002426 "ORF,_Verified" "T_subunit_of_the_mitochondrial_glycine_decarboxylase_complex,_required_for_the_catabolism_of_glycine_to_5,10-methylene-THF;_expression_is_regulated_by_levels_of_levels_of_5,10-methylene-THF_in_the_cytoplasm" YDR020C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 486442 485744 YDR020C S000002427 "ORF,_Uncharacterized" Predicted_protein_shares_weak_similarity_with_uridine_kinases_and_with_phosphoribokinases;_null_mutant_suppresses_dst1delta_sensitivity_for_6-azauracil YDR021W FAL1 None 35S_primary_transcript_processing ATP-dependent_RNA_helicase_activity nucleolus None None 4 486802 488001 YDR021W S000002428 "ORF,_Verified" "Nucleolar_protein_required_for_maturation_of_18S_rRNA,_member_of_the_eIF4A_subfamily_of_DEAD-box_ATP-dependent_RNA_helicases" YDR022C CIS1 ATG31 microtubule_cytoskeleton_organization_and_biogenesis molecular_function_unknown cytoplasm None None 4 488660 488070 YDR022C S000002429 "ORF,_Verified" Autophagy-specific_protein_required_for_autophagosome_formation;_may_form_a_complex_with_Atg17p_and_Atg29p_that_localizes_other_proteins_to_the_pre-autophagosomal_structure;_high-copy_suppressor_of_CIK1_deletion YDR023W SES1 None seryl-tRNA_aminoacylation serine-tRNA_ligase_activity cytoplasm None None 4 489506 490894 YDR023W S000002430 "ORF,_Verified" "Cytosolic_seryl-tRNA_synthetase,_class_II_aminoacyl-tRNA_synthetase_that_aminoacylates_tRNA(Ser),_displays_tRNA-dependent_amino_acid_recognition_which_enhances_discrimination_of_the_serine_substrate,_interacts_with_peroxin_Pex21p" YDR025W RPS11A None protein_biosynthesis* structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None Down 4 491513 492322 YDR025W S000002432 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_identical_to_Rps11Bp_and_has_similarity_to_E._coli_S17_and_rat_S11_ribosomal_proteins YDR027C VPS54 TCS3|CGP1|LUV1 Golgi_to_vacuole_transport* molecular_function_unknown mitochondrion* None None 4 497316 494647 YDR027C S000002434 "ORF,_Verified" "Component_of_the_GARP_(Golgi-associated_retrograde_protein)_complex,_Vps51p-Vps52p-Vps53p-Vps54p,_which_is_required_for_the_recycling_of_proteins_from_endosomes_to_the_late_Golgi;_potentially_phosphorylated_by_Cdc28p" YDR028C REG1 SRN1|SPP43|PZF240|HEX2 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter* protein_phosphatase_type_1_regulator_activity cytoplasm* None None 4 500877 497833 YDR028C S000002435 "ORF,_Verified" "Regulatory_subunit_of_type_1_protein_phosphatase_Glc7p,_involved_in_negative_regulation_of_glucose-repressible_genes" YDR032C PST2 None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 504693 504097 YDR032C S000002439 "ORF,_Verified" "Protein_with_similarity_to_members_of_a_family_of_flavodoxin-like_proteins;_induced_by_oxidative_stress_in_a_Yap1p_dependent_manner;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YDR034C LYS14 None lysine_biosynthesis_via_aminoadipic_acid transcriptional_activator_activity nucleus None None 4 512107 509735 YDR034C S000002441 "ORF,_Verified" Transcriptional_activator_involved_in_regulation_of_genes_of_the_lysine_biosynthesis_pathway;_requires_2-aminoadipate_semialdehyde_as_co-inducer YDR034C-A None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 520690 520514 YDR034C-A S000007233 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_contained_within_the_solo_Ty1_LTR_element_YDRWdelta7 YDR034C-C None None None None None None None 4 519354 518038 YDR034C-C S000007344 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YDR034C-D None None None None None None None 4 519354 514041 YDR034C-D S000007345 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YDR034W-B None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 521312 521467 YDR034W-B S000007234 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cell_periphery YDR035W ARO3 None aromatic_amino_acid_family_biosynthesis 3-deoxy-7-phosphoheptulonate_synthase_activity cytoplasm* None Up 4 521814 522926 YDR035W S000002442 "ORF,_Verified" "3-deoxy-D-arabino-heptulosonate-7-phosphate_(DAHP)_synthase,_catalyzes_the_first_step_in_aromatic_amino_acid_biosynthesis_and_is_feedback-inhibited_by_phenylalanine_or_high_concentration_of_tyrosine_or_tryptophan" YDR037W KRS1 GCD5 lysyl-tRNA_aminoacylation lysine-tRNA_ligase_activity cytoplasm None None 4 525438 527213 YDR037W S000002444 "ORF,_Verified" Lysyl-tRNA_synthetase YDR039C ENA2 None sodium_ion_transport "ATPase_activity,_coupled_to_transmembrane_movement_of_ions,_phosphorylative_mechanism" mitochondrion* None None 4 534580 531305 YDR039C S000002446 "ORF,_Verified" "P-type_ATPase_sodium_pump,_involved_in_Na+_efflux_to_allow_salt_tolerance;_likely_not_involved_in_Li+_efflux" YDR041W RSM10 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 4 539801 540412 YDR041W S000002448 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_small_subunit,_has_similarity_to_E._coli_S10_ribosomal_protein;_essential_for_viability,_unlike_most_other_mitoribosomal_proteins" YDR043C NRG1 None regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus None None 4 543368 542673 YDR043C S000002450 "ORF,_Verified" Transcriptional_repressor_that_recruits_the_Cyc8p-Tup1p_complex_to_promoters;_mediates_glucose_repression_and_negatively_regulates_a_variety_of_processes_including_filamentous_growth_and_alkaline_pH_response YDR044W HEM13 None heme_biosynthesis coproporphyrinogen_oxidase_activity mitochondrial_inner_membrane None Down 4 546641 547627 YDR044W S000002451 "ORF,_Verified" "Coproporphyrinogen_III_oxidase,_an_oxygen_requiring_enzyme_that_catalyzes_the_sixth_step_in_the_heme_biosynthetic_pathway;_localizes_to_the_mitochondrial_inner_membrane;_transcription_is_repressed_by_oxygen_and_heme_(via_Rox1p_and_Hap1p)" YDR047W HEM12 HEM6 heme_biosynthesis uroporphyrinogen_decarboxylase_activity cytoplasm* None None 4 551859 552947 YDR047W S000002454 "ORF,_Verified" "Uroporphyrinogen_decarboxylase,_catalyzes_the_fifth_step_in_the_heme_biosynthetic_pathway;_localizes_to_both_the_cytoplasm_and_nucleus;_activity_inhibited_by_Cu2+,_Zn2+,_Fe2+,_Fe3+_and_sulfhydryl-specific_reagents" YDR050C TPI1 None glycolysis triose-phosphate_isomerase_activity cytoplasm None None 4 556471 555725 YDR050C S000002457 "ORF,_Verified" "Triose_phosphate_isomerase,_abundant_glycolytic_enzyme;_mRNA_half-life_is_regulated_by_iron_availability;_transcription_is_controlled_by_activators_Reb1p,_Gcr1p,_and_Rap1p_through_binding_sites_in_the_5'_non-coding_region" YDR055W PST1 HPF2 cell_wall_organization_and_biogenesis molecular_function_unknown cell_wall_(sensu_Fungi) M/G1 None 4 563526 564860 YDR055W S000002462 "ORF,_Verified" "Cell_wall_protein_that_contains_a_putative_GPI-attachment_site;_secreted_by_regenerating_protoplasts;_up-regulated_by_activation_of_the_cell_integrity_pathway,_as_mediated_by_Rlm1p;_upregulated_by_cell_wall_damage_via_disruption_of_FKS1" YDR057W YOS9 None ER_to_Golgi_transport protein_transporter_activity endoplasmic_reticulum None None 4 565926 567554 YDR057W S000002464 "ORF,_Verified" "ER_quality-control_lectin;_integral_subunit_of_the_HRD_ligase;_serves_as_a_receptor_for_misfolded_N-glycosylated_proteins,_participates_in_their_targeting_to_ERAD;_member_of_the_OS-9_protein_family" YDR060W MAK21 NOC1 ribosomal_large_subunit_assembly_and_maintenance molecular_function_unknown Noc1p-Noc2p_complex None None 4 570647 573724 YDR060W S000002467 "ORF,_Verified" "Constituent_of_66S_pre-ribosomal_particles,_required_for_large_(60S)_ribosomal_subunit_biogenesis;_involved_in_nuclear_export_of_pre-ribosomes;_required_for_maintenance_of_dsRNA_virus;_homolog_of_human_CAATT-binding_protein" YDR062W LCB2 TSC1|SCS1 sphingolipid_biosynthesis serine_C-palmitoyltransferase_activity membrane_fraction* None None 4 576472 578157 YDR062W S000002469 "ORF,_Verified" "Component_of_serine_palmitoyltransferase,_responsible_along_with_Lcb1p_for_the_first_committed_step_in_sphingolipid_synthesis,_which_is_the_condensation_of_serine_with_palmitoyl-CoA_to_form_3-ketosphinganine" YDR063W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 578662 579111 YDR063W S000002470 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_null_mutant_is_viable_and_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation) YDR064W RPS13 RPS13C|RPS13B protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 4 579457 580451 YDR064W S000002471 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_has_similarity_to_E._coli_S15_and_rat_S13_ribosomal_proteins YDR066C RTR2 None biological_process_unknown molecular_function_unknown cytoplasm None None 4 582497 581907 YDR066C S000002473 "ORF,_Uncharacterized" Protein_of_unknown_function_with_high_similarity_to_Rtr1p;_exhibits_genetic_interactions_with_Rtr1p;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YDR066C_is_not_an_essential_gene YDR072C IPT1 KTI6|SYR4 sphingolipid_biosynthesis* "transferase_activity,_transferring_phosphorus-containing_groups" membrane_fraction None None 4 591343 589760 YDR072C S000002479 "ORF,_Verified" "Inositolphosphotransferase,_involved_in_synthesis_of_mannose-(inositol-P)2-ceramide_(M(IP)2C),_the_most_abundant_sphingolipid;,_can_mutate_to_resistance_to_the_antifungals_syringomycin_E_and_DmAMP1_and_to_K._lactis_zymocin" YDR074W TPS2 PFK3|HOG2 response_to_stress* trehalose-phosphatase_activity mitochondrion* None None 4 593891 596581 YDR074W S000002481 "ORF,_Verified" "Phosphatase_subunit_of_the_trehalose-6-phosphate_synthase/phosphatase_complex,_which_synthesizes_the_storage_carbohydrate_trehalose;_expression_is_induced_by_stress_conditions_and_repressed_by_the_Ras-cAMP_pathway" YDR077W SED1 None cell_wall_organization_and_biogenesis* structural_constituent_of_cell_wall mitochondrion* G2/M None 4 600791 601807 YDR077W S000002484 "ORF,_Verified" "Major_stress-induced_structural_GPI-cell_wall_glycoprotein_in_stationary-phase_cells,_associates_with_translating_ribosomes,_possible_role_in_mitochondrial_genome_maintenance;_ORF_contains_two_distinct_variable_minisatellites" YDR079W PET100 None aerobic_respiration* unfolded_protein_binding mitochondrial_inner_membrane None None 4 603062 603397 YDR079W S000002486 "ORF,_Verified" "Chaperone_that_specifically_facilitates_the_assembly_of_cytochrome_c_oxidase,_integral_to_the_mitochondrial_inner_membrane;_interacts_with_a_subcomplex_of_subunits_VII,_VIIa,_and_VIII_(Cox7p,_Cox9p,_and_Cox8p)_but_not_with_the_holoenzyme" YDR080W VPS41 VPL20|VAM2|SVL2|FET2|CVT8 "homotypic_vacuole_fusion,_non-autophagic*" Rab_guanyl-nucleotide_exchange_factor_activity vacuole_(sensu_Fungi)* None None 4 604006 606984 YDR080W S000002487 "ORF,_Verified" Vacuolar_membrane_protein_that_is_a_subunit_of_the_homotypic_vacuole_fusion_and_vacuole_protein_sorting_(HOPS)_complex;_essential_for_membrane_docking_and_fusion_at_the_Golgi-to-endosome_and_endosome-to-vacuole_stages_of_protein_transport YDR081C PDC2 None transcription_from_RNA_polymerase_II_promoter* transcription_regulator_activity nucleus None None 4 610079 607302 YDR081C S000002488 "ORF,_Verified" "Transcription_factor_required_for_the_synthesis_of_the_glycolytic_enzyme_pyruvate_decarboxylase,_required_for_high_level_expression_of_both_the_THI_and_the_PDC_genes" YDR082W STN1 None telomere_capping protein_binding nuclear_telomere_cap_complex None None 4 610439 611923 YDR082W S000002489 "ORF,_Verified" "Telomere_end-binding_and_capping_protein,_plays_a_key_role_with_Pol12p_in_linking_telomerase_action_with_completion_of_lagging_strand_synthesis,_and_in_a_regulatory_step_required_for_telomere_capping" YDR083W RRP8 None rRNA_processing methyltransferase_activity nucleolus None None 4 612071 613249 YDR083W S000002490 "ORF,_Verified" "Nucleolar_protein_involved_in_rRNA_processing,_pre-rRNA_cleavage_at_site_A2;_also_involved_in_telomere_maintenance;_mutation_is_synthetically_lethal_with_a_gar1_mutation" YDR084C TVP23 None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 614002 613403 YDR084C S000002491 "ORF,_Verified" Integral_membrane_protein_localized_to_late_Golgi_vesicles_along_with_the_v-SNARE_Tlg2p;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern YDR086C SSS1 None "SRP-dependent_cotranslational_protein_targeting_to_membrane,_translocation*" protein_transporter_activity endoplasmic_reticulum_membrane* None None 4 617168 616926 YDR086C S000002493 "ORF,_Verified" "Subunit_of_the_Sec61p_translocation_complex_(Sec61p-Sss1p-Sbh1p)_that_forms_a_channel_for_passage_of_secretory_proteins_through_the_endoplasmic_reticulum_membrane,_and_of_the_Ssh1p_complex_(Ssh1p-Sbh2p-Sss1p);_interacts_with_Ost4p_and_Wbp1p" YDR087C RRP1 None rRNA_processing molecular_function_unknown nucleus* None None 4 618304 617468 YDR087C S000002494 "ORF,_Verified" "Essential_evolutionarily_conserved_nucleolar_protein_necessary_for_biogenesis_of_60S_ribosomal_subunits_and_processing_of_pre-rRNAs_to_mature_rRNAs,_associated_with_several_distinct_66S_pre-ribosomal_particles" YDR090C None None biological_process_unknown molecular_function_unknown integral_to_membrane None None 4 625996 625064 YDR090C S000002497 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YDR091C RLI1 None translational_initiation* ATPase_activity* cytoplasm* None None 4 628532 626706 YDR091C S000002498 "ORF,_Verified" Essential_iron-sulfur_protein_required_for_ribosome_biogenesis_and_translation_initiation;_facilitates_binding_of_a_multifactor_complex_(MFC)_of_translation_initiation_factors_to_the_small_ribosomal_subunit;_predicted_ABC_family_ATPase YDR093W DNF2 None endocytosis* phospholipid-translocating_ATPase_activity plasma_membrane None None 4 631280 636118 YDR093W S000002500 "ORF,_Verified" "Aminophospholipid_translocase_(flippase)_that_localizes_primarily_to_the_plasma_membrane;_contributes_to_endocytosis,_protein_transport_and_cell_polarity;_type_4_P-type_ATPase" YDR096W GIS1 None spore_wall_assembly_(sensu_Fungi)* transcription_factor_activity nucleus* None None 4 637137 639821 YDR096W S000002503 "ORF,_Verified" JmjC_domain-containing_histone_demethylase;_transcription_factor_involved_in_the_expression_of_genes_during_nutrient_limitation;_also_involved_in_the_negative_regulation_of_DPP1_and_PHR1 YDR098C GRX3 None response_to_oxidative_stress thiol-disulfide_exchange_intermediate_activity nucleus* None None 4 645033 644176 YDR098C S000002505 "ORF,_Verified" Hydroperoxide_and_superoxide-radical_responsive_glutathione-dependent_oxidoreductase;_monothiol_glutaredoxin_subfamily_member_along_with_Grx4p_and_Grx5p;_protects_cells_from_oxidative_damage YDR098C-A None None None None None None None 4 651124 649802 YDR098C-A S000007390 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YDR098C-B None None None None None None None 4 651124 645856 YDR098C-B S000007391 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YDR100W TVP15 None biological_process_unknown molecular_function_unknown integral_to_Golgi_membrane* None None 4 655011 655442 YDR100W S000002507 "ORF,_Verified" Integral_membrane_protein_localized_to_late_Golgi_vesicles_along_with_the_v-SNARE_Tlg2p YDR103W STE5 NUL3|HMD3 invasive_growth_(sensu_Saccharomyces)* MAP-kinase_scaffold_activity cytoplasm* None None 4 658348 661101 YDR103W S000002510 "ORF,_Verified" "Pheromone-response_scaffold_protein;_binds_kinases_Ste11p,_Ste7p,_and_Fus3p_to_form_a_MAPK_cascade_complex_that_interacts_with_the_plasma_membrane_and_Ste4p-Ste18p;_modulates_the_sensitivity_of_Fus3p_to_pheromone_gradient" YDR104C SPO71 None spore_wall_assembly_(sensu_Fungi) molecular_function_unknown spore_wall_(sensu_Fungi) None None 4 664908 661171 YDR104C S000002511 "ORF,_Verified" "Meiosis-specific_protein_of_unknown_function,_required_for_spore_wall_formation_during_sporulation;_dispensable_for_both_nuclear_divisions_during_meiosis" YDR105C TMS1 None biological_process_unknown molecular_function_unknown membrane* None None 4 666768 665347 YDR105C S000002512 "ORF,_Verified" "Vacuolar_membrane_protein_of_unknown_function_that_is_conserved_in_mammals;_predicted_to_contain_eleven_transmembrane_helices;_interacts_with_Pdr5p,_a_protein_involved_in_multidrug_resistance" YDR108W GSG1 MUM1|TRS85 ER_to_Golgi_transport* molecular_function_unknown TRAPP_complex None None 4 671267 673363 YDR108W S000002515 "ORF,_Verified" "Subunit_of_TRAPP_(transport_protein_particle),_a_multi-subunit_complex_involved_in_targeting_and/or_fusion_of_ER-to-Golgi_transport_vesicles_with_their_acceptor_compartment;_protein_has_late_meiotic_role,_following_DNA_replication" YDR109C None None biological_process_unknown kinase_activity cellular_component_unknown None None 4 675665 673518 YDR109C S000002516 "ORF,_Uncharacterized" Putative_kinase YDR111C ALT2 None biological_process_unknown transaminase_activity cytoplasm* None None 4 679762 678239 YDR111C S000002518 "ORF,_Uncharacterized" Putative_alanine_transaminase_(glutamic_pyruvic_transaminase) YDR114C None None None None None None None 4 682224 681922 YDR114C S000002521 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_deletion_mutant_exhibits_poor_growth_at_elevated_pH_and_calcium YDR115W None None protein_biosynthesis* structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 4 682173 682490 YDR115W S000002522 "ORF,_Uncharacterized" "Putative_mitochondrial_ribosomal_protein_of_the_large_subunit,_has_similarity_to_E._coli_L34_ribosomal_protein;_required_for_respiratory_growth,_as_are_most_mitochondrial_ribosomal_proteins" YDR116C MRPL1 None protein_biosynthesis* structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 4 683579 682722 YDR116C S000002523 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YDR117C TMA64 RBF64 biological_process_unknown RNA_binding cellular_component_unknown None None 4 685641 683944 YDR117C S000002524 "ORF,_Verified" Protein_of_unknown_function_that_associates_with_ribosomes;_has_a_putative_RNA_binding_domain YDR118W APC4 None mitotic_sister_chromatid_segregation* protein_binding* anaphase-promoting_complex None None 4 685880 687838 YDR118W S000002525 "ORF,_Verified" "Subunit_of_the_Anaphase-Promoting_Complex/Cyclosome_(APC/C),_which_is_a_ubiquitin-protein_ligase_required_for_degradation_of_anaphase_inhibitors,_including_mitotic_cyclins,_during_the_metaphase/anaphase_transition" YDR119W VBA4 None biological_process_unknown molecular_function_unknown vacuolar_membrane_(sensu_Fungi) None None 4 688225 690531 YDR119W S000002526 "ORF,_Uncharacterized" Protein_of_unknown_function_with_proposed_role_as_a_basic_amino_acid_permease_based_on_phylogeny;_GFP-fusion_protein_localizes_to_vacuolar_membrane;_physical_interaction_with_Atg27p_suggests_a_possible_role_in_autophagy;_non-essential_gene YDR120C TRM1 None tRNA_methylation tRNA_(guanine-N2-)-methyltransferase_activity mitochondrion* None None 4 693259 691547 YDR120C S000002527 "ORF,_Verified" "tRNA_methyltransferase,_localizes_to_both_the_nucleus_and_mitochondrion_to_produce_the_modified_base_N2,N2-dimethylguanosine_in_tRNAs_in_both_compartments" YDR121W DPB4 None chromatin_silencing_at_telomere* epsilon_DNA_polymerase_activity epsilon_DNA_polymerase_complex* None None 4 693583 694173 YDR121W S000002528 "ORF,_Verified" Shared_subunit_of_DNA_polymerase_(II)_epsilon_and_of_ISW2/yCHRAC_chromatin_accessibility_complex;_involved_in_both_chromosomal_DNA_replication_and_in_inheritance_of_telomeric_silencing YDR123C INO2 SCS1|DIE1 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* specific_RNA_polymerase_II_transcription_factor_activity nucleus None None 4 699466 698552 YDR123C S000002530 "ORF,_Verified" "Component_of_the_heteromeric_Ino2p/Ino4p_basic_helix-loop-helix_transcription_activator_that_binds_inositol/choline-responsive_elements_(ICREs),_required_for_derepression_of_phospholipid_biosynthetic_genes_in_response_to_inositol_depletion" YDR124W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 700313 701287 YDR124W S000002531 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene;_expression_is_strongly_induced_by_alpha_factor YDR129C SAC6 ABP67 endocytosis* "protein_binding,_bridging*" actin_cortical_patch* None None 4 715377 713338 YDR129C S000002536 "ORF,_Verified" "Fimbrin,_actin-bundling_protein;_cooperates_with_Scp1p_(calponin/transgelin)_in_the_organization_and_maintenance_of_the_actin_cytoskeleton" YDR130C FIN1 None intermediate_filament-based_process protein_binding nucleus* S/G2 None 4 716620 715745 YDR130C S000002537 "ORF,_Verified" "Spindle_pole_body-related_intermediate_filament_protein,_forms_cell_cycle-specific_filaments_between_spindle_pole_bodies_in_mother_and_daughter_cells,_able_to_self-assemble,_expression_induced_during_S/G2,_localization_cell-cycle_dependent" YDR134C None None biological_process_unknown molecular_function_unknown cell_wall_(sensu_Fungi) None None 4 721479 721069 YDR134C S000002541 "pseudogene,_None" Hypothetical_protein YDR135C YCF1 None response_to_metal_ion* bilirubin_transporter_activity* vacuolar_membrane None None 4 727549 723002 YDR135C S000002542 "ORF,_Verified" "Vacuolar_glutathione_S-conjugate_transporter_of_the_ATP-binding_cassette_family,_has_a_role_in_detoxifying_metals_such_as_cadmium,_mercury,_and_arsenite;_also_transports_unconjugated_bilirubin;_similar_to_human_cystic_fibrosis_protein_CFTR" YDR137W RGP1 None intracellular_protein_transport guanyl-nucleotide_exchange_factor_activity Golgi_apparatus None None 4 728257 730248 YDR137W S000002544 "ORF,_Verified" Subunit_of_a_Golgi_membrane_exchange_factor_(Ric1p-Rgp1p)_that_catalyzes_nucleotide_exchange_on_Ypt6p YDR139C RUB1 None protein_neddylation protein_tag cytoplasm None None 4 733922 733616 YDR139C S000002546 "ORF,_Verified" "Ubiquitin-like_protein_with_similarity_to_mammalian_NEDD8;_conjugation_(neddylation)_substrates_include_the_cullins_Cdc53p,_Rtt101p,_and_Cul3p;_activated_by_Ula1p_and_Uba3p_(E1_enzyme_pair);_conjugation_mediated_by_Ubc12p_(E2_enzyme)" YDR140W MTQ2 None peptidyl-glutamine_methylation S-adenosylmethionine-dependent_methyltransferase_activity* cytoplasm* None None 4 734136 734801 YDR140W S000002547 "ORF,_Verified" S-adenosylmethionine-dependent_methyltransferase_of_the_seven_beta-strand_family;_subunit_of_complex_with_Trm112p_that_methylates_translation_release_factor_Sup45p_(eRF1)_in_the_ternary_complex_eRF1-eRF3-GTP;_similar_to_E.coli_PrmC YDR142C PEX7 PEB1|PAS7 peroxisome_organization_and_biogenesis* peroxisome_targeting_sequence_binding* cytosol* None None 4 741598 740471 YDR142C S000002549 "ORF,_Verified" Peroxisomal_signal_receptor_for_the_N-terminal_nonapeptide_signal_(PTS2)_of_peroxisomal_matrix_proteins;_WD_repeat_protein;_defects_in_human_homolog_cause_lethal_rhizomelic_chondrodysplasia_punctata_(RCDP) YDR143C SAN1 None response_to_stress* ubiquitin-protein_ligase_activity nucleus None None 4 743872 742040 YDR143C S000002550 "ORF,_Verified" "Ubiquitin-protein_ligase,_involved_in_the_proteasome-dependent_degradation_of_aberrant_nuclear_proteins" YDR145W TAF12 TAF68|TAF61 transcription_initiation_from_RNA_polymerase_II_promoter* general_RNA_polymerase_II_transcription_factor_activity SAGA_complex* None None 4 746736 748355 YDR145W S000002552 "ORF,_Verified" "Subunit_(61/68_kDa)_of_TFIID_and_SAGA_complexes,_involved_in_RNA_polymerase_II_transcription_initiation_and_in_chromatin_modification,_similar_to_histone_H2A" YDR146C SWI5 None G1-specific_transcription_in_mitotic_cell_cycle transcriptional_activator_activity cytoplasm* G2/M None 4 750740 748611 YDR146C S000002553 "ORF,_Verified" Transcription_factor_that_activates_transcription_of_genes_expressed_at_the_M/G1_phase_boundary_and_in_G1_phase;_localization_to_the_nucleus_occurs_during_G1_and_appears_to_be_regulated_by_phosphorylation_by_Cdc28p_kinase YDR147W EKI1 None phosphatidylethanolamine_biosynthesis choline_kinase_activity* cytoplasm None None 4 751629 753233 YDR147W S000002554 "ORF,_Verified" "Ethanolamine_kinase,_primarily_responsible_for_phosphatidylethanolamine_synthesis_via_the_CDP-ethanolamine_pathway;_exhibits_some_choline_kinase_activity,_thus_contributing_to_phosphatidylcholine_synthesis_via_the_CDP-choline_pathway" YDR148C KGD2 None tricarboxylic_acid_cycle* dihydrolipoyllysine-residue_succinyltransferase_activity mitochondrial_matrix* None None 4 755064 753673 YDR148C S000002555 "ORF,_Verified" "Dihydrolipoyl_transsuccinylase,_component_of_the_mitochondrial_alpha-ketoglutarate_dehydrogenase_complex,_which_catalyzes_the_oxidative_decarboxylation_of_alpha-ketoglutarate_to_succinyl-CoA_in_the_TCA_cycle;_phosphorylated" YDR150W NUM1 PAC12 "nuclear_migration,_microtubule-mediated*" tubulin_binding mitochondrion* S/G2 None 4 755626 763872 YDR150W S000002557 "ORF,_Verified" "Protein_required_for_nuclear_migration,_localizes_to_the_mother_cell_cortex_and_the_bud_tip;_may_mediate_interactions_of_dynein_and_cytoplasmic_microtubules_with_the_cell_cortex" YDR151C CTH1 None transcription* transcription_factor_activity nucleus None None 4 765153 764176 YDR151C S000002558 "ORF,_Verified" "Member_of_the_CCCH_zinc_finger_family;_has_similarity_to_mammalian_Tis11_protein,_which_activates_transcription_and_also_has_a_role_in_mRNA_degradation;_may_function_with_Tis11p_in_iron_homeostasis" YDR152W GIR2 None biological_process_unknown molecular_function_unknown cytoplasm None None 4 765704 766501 YDR152W S000002559 "ORF,_Verified" "Highly-acidic_cytoplasmic_RWD_domain-containing_protein_of_unknown_function,_sensitive_to_proteolysis,_N-terminal_region_has_high_content_of_acidic_amino_acid_residues,_putative_IUP_(intrinsically_unstructured_protein)" YDR158W HOM2 None methionine_metabolism* aspartate-semialdehyde_dehydrogenase_activity cytoplasm* None None 4 770355 771452 YDR158W S000002565 "ORF,_Verified" "Aspartic_beta_semi-aldehyde_dehydrogenase,_catalyzes_the_second_step_in_the_common_pathway_for_methionine_and_threonine_biosynthesis;_expression_regulated_by_Gcn4p_and_the_general_control_of_amino_acid_synthesis" YDR159W SAC3 LEP1 mRNA_export_from_nucleus* protein_binding nuclear_pore None None 4 771875 775780 YDR159W S000002566 "ORF,_Verified" "Nuclear_pore-associated_protein,_forms_a_complex_with_Thp1p_that_is_involved_in_transcription_and_in_mRNA_export_from_the_nucleus" YDR160W SSY1 SHR10 sensory_perception_of_chemical_stimulus amino_acid_binding plasma_membrane None None 4 776161 778719 YDR160W S000002567 "ORF,_Verified" "Component_of_the_SPS_plasma_membrane_amino_acid_sensor_system_(Ssy1p-Ptr3p-Ssy5p),_which_senses_external_amino_acid_concentration_and_transmits_intracellular_signals_that_result_in_regulation_of_expression_of_amino_acid_permease_genes" YDR161W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 779041 780204 YDR161W S000002568 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene;_proposed_function_in_rRNA_and_ribosome_biosynthesis_based_on_transcriptional_co-regulation YDR162C NBP2 None response_to_heat* molecular_function_unknown cytoplasm* None None 4 781098 780388 YDR162C S000002569 "ORF,_Verified" "Protein_involved_in_the_HOG_(high_osmolarity_glycerol)_pathway,_negatively_regulates_Hog1p_by_recruitment_of_phosphatase_Ptc1p_the_Pbs2p-Hog1p_complex,_found_in_the_nucleus_and_cytoplasm,_contains_an_SH3_domain_that_binds_Pbs2p" YDR164C SEC1 None vesicle_fusion* SNARE_binding plasma_membrane* None None 4 784213 782039 YDR164C S000002571 "ORF,_Verified" Sm-like_protein_involved_in_docking_and_fusion_of_exocytic_vesicles_through_binding_to_assembled_SNARE_complexes_at_the_membrane;_localization_to_sites_of_secretion_(bud_neck_and_bud_tip)_is_dependent_on_SNARE_function YDR166C SEC5 None cytokinesis* protein_binding bud_neck* None Up 4 789219 786304 YDR166C S000002573 "ORF,_Verified" "Essential_107kDa_subunit_of_the_exocyst_complex_(Sec3p,_Sec5p,_Sec6p,_Sec8p,_Sec10p,_Sec15p,_Exo70p,_and_Exo84p),_which_has_the_essential_function_of_mediating_polarized_targeting_of_secretory_vesicles_to_active_sites_of_exocytosis" YDR167W TAF10 TAF25|TAF23 transcription_initiation_from_RNA_polymerase_II_promoter* general_RNA_polymerase_II_transcription_factor_activity SAGA_complex* None None 4 789447 790067 YDR167W S000002574 "ORF,_Verified" "Subunit_(145_kDa)_of_TFIID_and_SAGA_complexes,_involved_in_RNA_polymerase_II_transcription_initiation_and_in_chromatin_modification" YDR168W CDC37 SMO1 signal_transduction* unfolded_protein_binding cytoplasm None None 4 790326 791846 YDR168W S000002575 "ORF,_Verified" Essential_Hsp90p_co-chaperone;_necessary_for_passage_through_the_START_phase_of_the_cell_cycle;_stabilizes_protein_kinase_nascent_chains_and_participates_along_with_Hsp90p_in_their_folding YDR169C STB3 None biological_process_unknown molecular_function_unknown cytoplasm None None 4 793887 792346 YDR169C S000002576 "ORF,_Verified" Protein_that_binds_Sin3p_in_a_two-hybrid_assay YDR170W-A None None None None None None None 4 803193 804515 YDR170W-A S000007227 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag;_YDR170W-A_is_part_of_a_mutant_retrotransposon YDR171W HSP42 None response_to_stress* unfolded_protein_binding cytoplasm* None None 4 806619 807746 YDR171W S000002578 "ORF,_Verified" Small_heat_shock_protein_(sHSP)_with_chaperone_activity;_forms_barrel-shaped_oligomers_that_suppress_unfolded_protein_aggregation;_involved_in_cytoskeleton_reorganization_after_heat_shock YDR172W SUP35 [PSI(+)]|[PSI]|SUP36|SUP2|SUF12|SAL3|PNM2|GST1 "mRNA_catabolism,_deadenylylation-dependent_decay*" translation_release_factor_activity cytosol* None None 4 808322 810379 YDR172W S000002579 "ORF,_Verified" "Translation_termination_factor_eRF3;_altered_protein_conformation_creates_the_[PSI(+)]_prion,_a_dominant_cytoplasmically_inherited_protein_aggregate_that_alters_translational_fidelity_and_creates_a_nonsense_suppressor_phenotype" YDR173C ARG82 ARGRIII|IPK2|ARGR3 arginine_metabolism* inositol_or_phosphatidylinositol_kinase_activity nucleus None None 4 811630 810563 YDR173C S000002580 "ORF,_Verified" "Inositol_polyphosphate_multikinase_(IPMK),_sequentially_phosphorylates_Ins(1,4,5)P3_to_form_Ins(1,3,4,5,6)P5;_also_has_diphosphoinositol_polyphosphate_synthase_activity;_regulates_arginine-,_phosphate-,_and_nitrogen-responsive_genes" YDR174W HMO1 HSM2 plasmid_maintenance single-stranded_DNA_binding* cytoplasm* None None 4 812108 812848 YDR174W S000002581 "ORF,_Verified" "Chromatin_associated_high_mobility_group_(HMG)_family_member_involved_in_genome_maintenance;_rDNA-binding_component_of_the_Pol_I_transcription_system;_associates_with_a_5'-3'_DNA_helicase_and_Fpr1p,_a_prolyl_isomerase" YDR175C RSM24 None protein_biosynthesis* structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 4 814150 813191 YDR175C S000002582 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YDR176W NGG1 SWI7|ADA3 histone_acetylation* transcription_cofactor_activity SAGA_complex* None None 4 814450 816558 YDR176W S000002583 "ORF,_Verified" "Transcriptional_regulator_involved_in_glucose_repression_of_Gal4p-regulated_genes;_component_of_transcriptional_adaptor_and_histone_acetyltransferase_complexes,_the_ADA_complex,_the_SAGA_complex,_and_the_SLIK_complex" YDR177W UBC1 None endocytosis* ubiquitin_conjugating_enzyme_activity proteasome_complex_(sensu_Eukaryota) None None 4 816876 817523 YDR177W S000002584 "ORF,_Verified" Ubiquitin-conjugating_enzyme_that_mediates_selective_degradation_of_short-lived_and_abnormal_proteins;_plays_a_role_in_vesicle_biogenesis_and_ER-associated_protein_degradation_(ERAD);_component_of_the_cellular_stress_response YDR179C CSN9 None adaptation_to_pheromone_during_conjugation_with_cellular_fusion* molecular_function_unknown signalosome_complex None None 4 819194 818706 YDR179C S000002586 "ORF,_Verified" "Subunit_of_the_Cop9_signalosome,_which_is_required_for_deneddylation,_or_removal_of_the_ubiquitin-like_protein_Rub1p_from_Cdc53p_(cullin);_involved_in_adaptation_to_pheromone_signaling" YDR182W CDC1 ESP2|DSR1|DSC1 DNA_repair* molecular_function_unknown integral_to_membrane None None 4 827580 829055 YDR182W S000002590 "ORF,_Verified" Putative_lipid_phosphatase_of_the_endoplasmic_reticulum;_shows_Mn2+_dependence_and_may_affect_Ca2+_signaling;_mutants_display_actin_and_general_growth_defects_and_pleiotropic_defects_in_cell_cycle_progression_and_organelle_distribution YDR183W PLP1 None beta-tubulin_folding* GTPase_inhibitor_activity cytoplasm None None 4 829583 830275 YDR183W S000002591 "ORF,_Verified" "Protein_with_a_possible_role_in_folding_of_beta-tubulin;_has_weak_similarity_to_phosducins,_which_are_G-protein_regulators" YDR184C ATC1 LIC4 response_to_stress* molecular_function_unknown nucleus None None 4 831511 830627 YDR184C S000002592 "ORF,_Verified" "Nuclear_protein,_possibly_involved_in_regulation_of_cation_stress_responses_and/or_in_the_establishment_of_bipolar_budding_pattern" YDR185C None None biological_process_unknown molecular_function_unknown mitochondrion None None 4 832471 831932 YDR185C S000002593 "ORF,_Uncharacterized" "Mitochondrial_protein_of_unknown_function;_has_similarity_to_Ups1p,_which_is_involved_in_regulation_of_alternative_topogenesis_of_the_dynamin-related_GTPase_Mgm1p" YDR186C None None biological_process_unknown molecular_function_unknown cytoplasm None None 4 835490 832857 YDR186C S000002594 "ORF,_Verified" "Putative_protein_of_unknown_function;_may_interact_with_ribosomes,_based_on_co-purification_experiments;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm" YDR188W CCT6 TCP20|TCP6|HTR3 protein_folding* unfolded_protein_binding cytoplasm* None None 4 836419 838059 YDR188W S000002596 "ORF,_Verified" "Subunit_of_the_cytosolic_chaperonin_Cct_ring_complex,_related_to_Tcp1p,_essential_protein_that_is_required_for_the_assembly_of_actin_and_tubulins_in_vivo;_contains_an_ATP-binding_motif" YDR190C RVB1 TIP48|TIH1|TIP49A regulation_of_transcription_from_RNA_polymerase_II_promoter* ATPase_activity nucleus* G2/M None 4 841993 840602 YDR190C S000002598 "ORF,_Verified" Essential_protein_involved_in_transcription_regulation;_component_of_chromatin_remodeling_complexes;_required_for_assembly_and_function_of_the_INO80_complex;_member_of_the_RUVB-like_protein_family YDR191W HST4 None chromatin_silencing_at_telomere* DNA_binding cytoplasm* M/G1 None 4 842335 843447 YDR191W S000002599 "ORF,_Verified" "Member_of_the_Sir2_family_of_NAD(+)-dependent_protein_deacetylases;_involved_along_with_Hst3p_in_silencing_at_telomeres,_cell_cycle_progression,_radiation_resistance,_genomic_stability_and_short-chain_fatty_acid_metabolism" YDR192C NUP42 UIP1|RIP1 mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 4 844859 843567 YDR192C S000002600 "ORF,_Verified" "Subunit_of_the_nuclear_pore_complex_(NPC)_that_localizes_exclusively_to_the_cytoplasmic_side;_involved_in_RNA_export,_most_likely_at_a_terminal_step;_interacts_with_Gle1p" YDR194C MSS116 None RNA_splicing "RNA_splicing_factor_activity,_transesterification_mechanism*" mitochondrial_matrix None None 4 847944 845950 YDR194C S000002602 "ORF,_Verified" DEAD-box_protein_required_for_efficient_splicing_of_mitochondrial_Group_I_and_II_introns;_non-polar_RNA_helicase_that_also_facilities_strand_annealing YDR195W REF2 None "transcription_termination_from_Pol_II_promoter,_RNA_polymerase(A)_coupled*" RNA_binding* nucleus* None None 4 848597 850198 YDR195W S000002603 "ORF,_Verified" "RNA-binding_protein_involved_in_the_cleavage_step_of_mRNA_3'-end_formation_prior_to_polyadenylation,_and_in_snoRNA_maturation;_part_of_holo-CPF_subcomplex_APT,_which_associates_with_3'-ends_of_snoRNA-_and_mRNA-encoding_genes" YDR196C None None coenzyme_A_biosynthesis dephospho-CoA_kinase_activity endoplasmic_reticulum* None None 4 850997 850272 YDR196C S000002604 "ORF,_Uncharacterized" "Putative_dephospho-CoA_kinase_(DPCK)_that_catalyzes_the_final_step_in_Coenzyme_A_biosynthesis;_essential_for_viability;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YDR197W CBS2 CBP7 protein_biosynthesis molecular_function_unknown mitochondrial_inner_membrane None None 4 851226 852395 YDR197W S000002605 "ORF,_Verified" "Mitochondrial_translational_activator_of_the_COB_mRNA;_interacts_with_translating_ribosomes,_acts_on_the_COB_mRNA_5'-untranslated_leader" YDR198C RKM2 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 853970 852531 YDR198C S000002606 "ORF,_Verified" "Ribosomal_protein_lysine_methyltransferase,_responsible_for_epsilon-trimethylation_of_the_lysine_residue_at_position_10_of_Rpl12Ap_and_Rpl12Bp" YDR205W MSC2 None zinc_ion_homeostasis cation:cation_antiporter_activity nucleus* None None 4 859344 861518 YDR205W S000002613 "ORF,_Verified" "Member_of_the_cation_diffusion_facilitator_family,_localizes_to_the_endoplasmic_reticulum_and_nucleus;_mutations_affect_the_cellular_distribution_of_zinc_and_also_confer_defects_in_meiotic_recombination_between_homologous_chromatids" YDR207C UME6 RIM16|NIM2|CAR80 sporulation_(sensu_Fungi)* DNA_binding* nucleus None None 4 867520 865010 YDR207C S000002615 "ORF,_Verified" "Key_transcriptional_regulator_of_early_meiotic_genes,_binds_URS1_upstream_regulatory_sequence,_couples_metabolic_responses_to_nutritional_cues_with_initiation_and_progression_of_meiosis,_forms_complex_with_Ime1p,_and_also_with_Sin3p-Rpd3p" YDR208W MSS4 None sporulation_(sensu_Fungi)* 1-phosphatidylinositol-4-phosphate_5-kinase_activity plasma_membrane None None 4 868222 870561 YDR208W S000002616 "ORF,_Verified" "Phosphatidylinositol-4-phosphate_5-kinase,_involved_in_actin_cytoskeleton_organization_and_cell_morphogenesis;_multicopy_suppressor_of_stt4_mutation" YDR210C-C None YDR210W-C None None None None None 4 883925 882603 YDR210W-C S000007409 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YDR210C-D None YDR210W-D None None None None None 4 883925 878657 YDR210W-D S000007410 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YDR210W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 871072 871299 YDR210W S000002618 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cell_periphery YDR210W-A None None None None None None None 4 872110 873426 YDR210W-A S000007392 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YDR210W-B None None None None None None None 4 872110 877423 YDR210W-B S000007393 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YDR211W GCD6 None translational_initiation translation_initiation_factor_activity* ribosome* None None 4 884725 886863 YDR211W S000002619 "ORF,_Verified" "Catalytic_epsilon_subunit_of_the_translation_initiation_factor_eIF2B,_the_guanine-nucleotide_exchange_factor_for_eIF2;_activity_subsequently_regulated_by_phosphorylated_eIF2;_first_identified_as_a_negative_regulator_of_GCN4_expression" YDR212W TCP1 CCT1 protein_folding* unfolded_protein_binding cytoplasm* None None 4 887230 888909 YDR212W S000002620 "ORF,_Verified" "Alpha_subunit_of_chaperonin-containing_T-complex,_which_mediates_protein_folding_in_the_cytosol;_involved_in_maintenance_of_actin_cytoskeleton;_homolog_to_Drosophila_melanogaster_and_mouse_tailless_complex_polypeptide" YDR213W UPC2 MOX4 sterol_biosynthesis* RNA_polymerase_II_transcription_factor_activity cytoplasm* None None 4 889749 892490 YDR213W S000002621 "ORF,_Verified" "Sterol_regulatory_element_binding_protein,_induces_transcription_of_sterol_transport_and_biosynthetic_genes;_involved_in_the_anaerobic_induction_of_DAN/TIR_mannoproteins_and_seripauperins;_binucleate_zinc_cluster_protein;_Ecm22p_homolog" YDR214W AHA1 None response_to_stress* chaperone_activator_activity cytoplasm None None 4 892873 893925 YDR214W S000002622 "ORF,_Verified" Co-chaperone_that_binds_to_Hsp82p_and_activates_its_ATPase_activity;_similar_to_Hch1p;_expression_is_regulated_by_stresses_such_as_heat_shock YDR221W GTB1 None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 4 907327 909435 YDR221W S000002629 "ORF,_Verified" "Glucosidase_II_beta_subunit,_forms_a_complex_with_alpha_subunit_Rot2p,_involved_in_removal_of_two_glucose_residues_from_N-linked_glycans_during_glycoprotein_biogenesis_in_the_ER" YDR222W None None biological_process_unknown molecular_function_unknown cytoplasm None None 4 910051 911298 YDR222W S000002630 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern YDR224C HTB1 SPT12 chromatin_assembly_or_disassembly* DNA_binding nuclear_nucleosome S None 4 914709 914314 YDR224C S000002632 "ORF,_Verified" "Histone_H2B,_core_histone_protein_required_for_chromatin_assembly_and_chromosome_function;_nearly_identical_to_HTB2;_Rad6p-Bre1p-Lge1p_mediated_ubiquitination_regulates_transcriptional_activation,_meiotic_DSB_formation_and_H3_methylation" YDR225W HTA1 SPT11|H2A1 DNA_repair* DNA_binding nuclear_nucleosome S Down 4 915527 915925 YDR225W S000002633 "ORF,_Verified" "Histone_H2A,_core_histone_protein_required_for_chromatin_assembly_and_chromosome_function;_one_of_two_nearly_identical_subtypes_(see_also_HTA2);_DNA_damage-dependent_phosphorylation_by_Mec1p_facilitates_DNA_repair;_acetylated_by_Nat4p" YDR226W ADK1 AKY2|AKY1 nucleotide_metabolism* adenylate_kinase_activity cytoplasm* None None 4 916483 917151 YDR226W S000002634 "ORF,_Verified" "Adenylate_kinase,_required_for_purine_metabolism;_localized_to_the_cytoplasm_and_the_mitochondria;_lacks_cleavable_signal_sequence" YDR227W SIR4 UTH2|STE9|ASD1 double-strand_break_repair_via_nonhomologous_end-joining* histone_binding* nuclear_telomere_cap_complex* None None 4 917568 921644 YDR227W S000002635 "ORF,_Verified" "Silent_information_regulator_that,_together_with_SIR2_and_SIR3,_is_involved_in_assembly_of_silent_chromatin_domains_at_telomeres_and_the_silent_mating-type_loci;_potentially_phosphorylated_by_Cdc28p;_some_alleles_of_SIR4_prolong_lifespan" YDR229W IVY1 None secretory_pathway phospholipid_binding vacuolar_membrane_(sensu_Fungi) None None 4 924782 926143 YDR229W S000002637 "ORF,_Verified" "Phospholipid-binding_protein_that_interacts_with_both_Ypt7p_and_Vps33p,_may_partially_counteract_the_action_of_Vps33p_and_vice_versa,_localizes_to_the_rim_of_the_vacuole_as_cells_approach_stationary_phase" YDR231C COX20 None aerobic_respiration* unfolded_protein_binding mitochondrial_inner_membrane None None 4 926907 926290 YDR231C S000002639 "ORF,_Verified" "Mitochondrial_inner_membrane_protein,_required_for_proteolytic_processing_of_Cox2p_and_its_assembly_into_cytochrome_c_oxidase" YDR232W HEM1 CYD1 heme_biosynthesis 5-aminolevulinate_synthase_activity mitochondrial_matrix None None 4 927449 929095 YDR232W S000002640 "ORF,_Verified" "5-aminolevulinate_synthase,_catalyzes_the_first_step_in_the_heme_biosynthetic_pathway;_an_N-terminal_signal_sequence_is_required_for_localization_to_the_mitochondrial_matrix;_expression_is_regulated_by_Hap2p-Hap3p" YDR233C RTN1 None biological_process_unknown molecular_function_unknown mitochondrion* None None 4 930354 929467 YDR233C S000002641 "ORF,_Verified" ER_membrane_protein_that_interacts_with_exocyst_subunit_Sec6p_and_with_Yip3p;_also_interacts_with_Sbh1p;_null_mutant_has_an_altered_(mostly_cisternal)_ER_morphology;_member_of_the_RTNLA_(reticulon-like_A)_subfamily YDR234W LYS4 LYS3 lysine_biosynthesis_via_aminoadipic_acid homoaconitate_hydratase_activity mitochondrion* None None 4 931126 933207 YDR234W S000002642 "ORF,_Verified" "Homoaconitase,_catalyzes_the_conversion_of_homocitrate_to_homoisocitrate,_which_is_a_step_in_the_lysine_biosynthesis_pathway" YDR237W MRPL7 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 4 936612 937490 YDR237W S000002645 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YDR239C None None biological_process_unknown molecular_function_unknown cytoplasm None Up 4 943417 941054 YDR239C S000002647 "ORF,_Verified" "Protein_of_unknown_function_that_may_interact_with_ribosomes,_based_on_co-purification_experiments" YDR243C PRP28 None cis_assembly_of_U2-type_pre-catalytic_spliceosome "RNA_splicing_factor_activity,_transesterification_mechanism*" spliceosome_complex* None None 4 950281 948515 YDR243C S000002651 "ORF,_Verified" "RNA_helicase_in_the_DEAD-box_family,_involved_in_RNA_isomerization_at_the_5'_splice_site" YDR244W PEX5 PAS10 peroxisome_organization_and_biogenesis* peroxisome_targeting_sequence_binding* cytosol* None None 4 950560 952398 YDR244W S000002652 "ORF,_Verified" "Peroxisomal_membrane_signal_receptor_for_the_C-terminal_tripeptide_signal_sequence_(PTS1)_of_peroxisomal_matrix_proteins,_required_for_peroxisomal_matrix_protein_import;_also_proposed_to_have_PTS1-receptor_independent_functions" YDR245W MNN10 REC41|SLC2|BED1 actin_filament_organization* "alpha-1,6-mannosyltransferase_activity" "alpha-1,6-mannosyltransferase_complex" None None 4 952797 953978 YDR245W S000002653 "ORF,_Verified" "Subunit_of_a_Golgi_mannosyltransferase_complex_also_containing_Anp1p,_Mnn9p,_Mnn11p,_and_Hoc1p_that_mediates_elongation_of_the_polysaccharide_mannan_backbone;_membrane_protein_of_the_mannosyltransferase_family" YDR246W TRS23 None ER_to_Golgi_transport molecular_function_unknown TRAPP_complex None None 4 954285 954944 YDR246W S000002654 "ORF,_Verified" One_of_10_subunits_of_the_transport_protein_particle_(TRAPP)_complex_of_the_cis-Golgi_which_mediates_vesicle_docking_and_fusion;_involved_in_endoplasmic_reticulum_(ER)_to_Golgi_membrane_traffic;_human_homolog_is_TRAPPC4 YDR253C MET32 None sulfur_amino_acid_metabolism DNA_binding* nucleus None None 4 964562 963987 YDR253C S000002661 "ORF,_Verified" "Zinc-finger_DNA-binding_protein,_involved_in_transcriptional_regulation_of_the_methionine_biosynthetic_genes,_similar_to_Met31p" YDR254W CHL4 MCM17|CTF17 chromosome_segregation DNA_binding outer_kinetochore_of_condensed_nuclear_chromosome None None 4 965110 966486 YDR254W S000002662 "ORF,_Verified" "Outer_kinetochore_protein_required_for_chromosome_stability,_interacts_with_kinetochore_proteins_Ctf19p,_Ctf3p,_and_Iml3p;_exhibits_a_two-hybrid_interaction_with_Mif2p;_association_with_CEN_DNA_requires_Ctf19p" YDR255C RMD5 GID2 negative_regulation_of_gluconeogenesis molecular_function_unknown cytosol None None 4 967819 966554 YDR255C S000002663 "ORF,_Verified" "Conserved_protein_that_has_an_E3-like_ubiquitin_ligase_activity_necessary_for_polyubiquitination_and_degradation_of_the_gluconeogenic_enzyme_fructose-1,6-bisphosphatase;_also_required_for_sporulation;_has_a_degenerate_RING_finger_domain" YDR259C YAP6 HAL7 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_factor_activity nucleus None None 4 975779 974628 YDR259C S000002667 "ORF,_Verified" Putative_basic_leucine_zipper_(bZIP)_transcription_factor;_overexpression_increases_sodium_and_lithium_tolerance;_computational_analysis_suggests_a_role_in_regulation_of_expression_of_genes_involved_in_carbohydrate_metabolism YDR261C EXG2 None cell_wall_organization_and_biogenesis "glucan_1,3-beta-glucosidase_activity" cell_wall_(sensu_Fungi) S None 4 979206 977518 YDR261C S000002669 "ORF,_Verified" "Exo-1,3-beta-glucanase,_involved_in_cell_wall_beta-glucan_assembly;_may_be_anchored_to_the_plasma_membrane_via_a_glycosylphosphatidylinositol_(GPI)_anchor" YDR261C-C None None None None None None None 4 992346 991024 YDR261C-C S000007394 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_in_YDRCTY1-3_TYB_is_mutant_and_probably_non-functional YDR261C-D None None None None None None None 4 992346 987531 YDR261C-D S000007395 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_in_YDRCTY1-3_TYB_is_mutant_and_probably_non-functional YDR261W-A None None None None None None None 4 981459 982775 YDR261W-A S000007396 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YDR261W-B None None None None None None None 4 981459 986772 YDR261W-B S000007397 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YDR262W None None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) None None 4 993131 993949 YDR262W S000002670 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuole_and_is_induced_in_response_to_the_DNA-damaging_agent_MMS;_gene_expression_increases_in_response_to_Zymoliase_treatment YDR263C DIN7 DIN3 DNA_repair nuclease_activity mitochondrion None None 4 995531 994239 YDR263C S000002671 "ORF,_Verified" "Mitochondrial_nuclease_functioning_in_DNA_repair_and_replication,_modulates_the_stability_of_the_mitochondrial_genome,_induced_by_exposure_to_mutagens,_also_induced_during_meiosis_at_a_time_nearly_coincident_with_commitment_to_recombination" YDR264C AKR1 None endocytosis* protein-cysteine_S-palmitoleyltransferase_activity membrane None None 4 998320 996026 YDR264C S000002672 "ORF,_Verified" Palmitoyl_transferase_involved_in_protein_palmitoylation;_acts_as_a_negative_regulator_of_pheromone_response_pathway;_required_for_endocytosis_of_pheromone_receptors;_involved_in_cell_shape_control;_contains_ankyrin_repeats YDR265W PEX10 PAS4 peroxisome_organization_and_biogenesis protein_binding peroxisomal_membrane None None 4 998861 999874 YDR265W S000002673 "ORF,_Verified" Peroxisomal_membrane_E3_ubiquitin_ligase_required_for_for_Ubc4p-dependent_Pex5p_ubiquitination_and_peroxisomal_matrix_protein_import;_contains_zinc-binding_RING_domain;_mutations_in_human_homolog_cause_various_peroxisomal_disorders YDR266C None None biological_process_unknown molecular_function_unknown cytoplasm None None 4 1002020 1000101 YDR266C S000002674 "ORF,_Verified" "Protein_of_unknown_function_that_may_interact_with_ribosomes,_based_on_co-purification_experiments;green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_contains_a_RING_finger_domain" YDR267C CIA1 None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 1003499 1002507 YDR267C S000002675 "ORF,_Verified" Essential_protein_involved_in_assembly_of_cytosolic_and_nuclear_iron-sulfur_proteins YDR272W GLO2 None carbohydrate_metabolism* hydroxyacylglutathione_hydrolase_activity cytoplasm None None 4 1009007 1009831 YDR272W S000002680 "ORF,_Verified" "Cytoplasmic_glyoxalase_II,_catalyzes_the_hydrolysis_of_S-D-lactoylglutathione_into_glutathione_and_D-lactate" YDR273W DON1 None meiosis* molecular_function_unknown spindle* None None 4 1010173 1011270 YDR273W S000002681 "ORF,_Verified" "Meiosis-specific_component_of_the_spindle_pole_body,_part_of_the_leading_edge_protein_(LEP)_coat,_forms_a_ring-like_structure_at_the_leading_edge_of_the_prospore_membrane_during_meiosis_II" YDR275W BSC2 None biological_process_unknown molecular_function_unknown lipid_particle None None 4 1012249 1012956 YDR275W S000002683 "ORF,_Verified" "Protein_of_unknown_function,_ORF_exhibits_genomic_organization_compatible_with_a_translational_readthrough-dependent_mode_of_expression" YDR276C PMP3 SNA1 cation_transport molecular_function_unknown plasma_membrane G2/M None 4 1013640 1013473 YDR276C S000002684 "ORF,_Verified" "Small_plasma_membrane_protein_related_to_a_family_of_plant_polypeptides_that_are_overexpressed_under_high_salt_concentration_or_low_temperature,_not_essential_for_viability,_deletion_causes_hyperpolarization_of_the_plasma_membrane_potential" YDR277C MTH1 HTR1|DGT1|BPC1 signal_transduction* molecular_function_unknown cellular_component_unknown None None 4 1015699 1014398 YDR277C S000002685 "ORF,_Verified" "Negative_regulator_of_the_glucose-sensing_signal_transduction_pathway,_required_for_repression_of_transcription_by_Rgt1p;_interacts_with_Rgt1p_and_the_Snf3p_and_Rgt2p_glucose_sensors;_phosphorylated_by_Yck1p,_triggering_Mth1p_degradation" YDR279W RNH202 None DNA_replication ribonuclease_H_activity nucleus G1 None 4 1019365 1020417 YDR279W S000002687 "ORF,_Verified" "Ribonuclease_H2_subunit,_required_for_RNase_H2_activity" YDR280W RRP45 None 35S_primary_transcript_processing* 3'-5'-exoribonuclease_activity nuclear_exosome_(RNase_complex)* None None 4 1020744 1021661 YDR280W S000002688 "ORF,_Verified" Protein_involved_in_rRNA_processing;_component_of_the_exosome_3->5_exonuclease_complex YDR281C PHM6 None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) None None 4 1022318 1022004 YDR281C S000002689 "ORF,_Verified" "Protein_of_unknown_function,_expression_is_regulated_by_phosphate_levels" YDR282C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1024752 1023508 YDR282C S000002690 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YDR285W ZIP1 None synapsis chromatin_binding transverse_filament None None 4 1032433 1035060 YDR285W S000002693 "ORF,_Verified" Transverse_filament_protein_of_the_synaptonemal_complex;_required_for_normal_levels_of_meiotic_recombination_and_pairing_between_homologous_chromosome_during_meiosis;_potential_Cdc28p_substrate YDR286C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1035572 1035228 YDR286C S000002694 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_predicted_to_have_thiol-disulfide_oxidoreductase_active_site YDR287W INM2 None inositol_phosphate_dephosphorylation inositol-1(or_4)-monophosphatase_activity cellular_component_unknown None None 4 1035992 1036870 YDR287W S000002695 "ORF,_Verified" "Inositol_monophosphatase,_involved_in_biosynthesis_of_inositol;_enzymatic_activity_requires_magnesium_ions_and_is_inhibited_by_lithium_and_sodium_ions;_inm1_inm2_double_mutant_lacks_inositol_auxotrophy" YDR288W NSE3 None DNA_repair DNA_binding cytoplasm* None None 4 1037192 1038103 YDR288W S000002696 "ORF,_Verified" Essential_subunit_of_the_Mms21-Smc5-Smc6_complex;_protein_of_unknown_function;_required_for_DNA_repair_and_growth YDR289C RTT103 None "transcription_termination_from_Pol_II_promoter,_RNA_polymerase(A)_coupled*" molecular_function_unknown cellular_component_unknown None None 4 1039506 1038277 YDR289C S000002697 "ORF,_Verified" "Protein_that_interacts_with_exonuclease_Rat1p_and_Rai1p_and_plays_a_role_in_transcription_termination_by_RNA_polymerase_II,_has_an_RPR_domain_(carboxy-terminal_domain_interacting_domain);_also_involved_in_regulation_of_Ty1_transposition" YDR292C SRP101 None protein_targeting_to_ER* GTP_binding* endoplasmic_reticulum_membrane* None None 4 1045008 1043143 YDR292C S000002700 "ORF,_Verified" Signal_recognition_particle_(SRP)_receptor_-_alpha_subunit;_contain_GTPase_domains;_involved_in_SRP-dependent_protein_targeting;_interacts_with_Srp102p YDR293C SSD1 SRK1|RLT1|MCS1|CLA1 cell_wall_organization_and_biogenesis RNA_binding cytoplasm None None 4 1049389 1045637 YDR293C S000002701 "ORF,_Verified" "Protein_with_a_role_in_maintenance_of_cellular_integrity,_interacts_with_components_of_the_TOR_pathway;_ssd1_mutant_of_a_clinical_S._cerevisiae_strain_displays_elevated_virulence" YDR294C DPL1 BST1 sphingolipid_metabolism* sphinganine-1-phosphate_aldolase_activity endoplasmic_reticulum None None 4 1052225 1050456 YDR294C S000002702 "ORF,_Verified" "Dihydrosphingosine_phosphate_lyase,_regulates_intracellular_levels_of_sphingolipid_long-chain_base_phosphates_(LCBPs),_degrades_phosphorylated_long_chain_bases,_prefers_C16_dihydrosphingosine-l-phosphate_as_a_substrate" YDR295C HDA2 PLO2 "regulation_of_transcription,_DNA-dependent*" histone_deacetylase_activity nucleus* None None 4 1054644 1052620 YDR295C S000002703 "ORF,_Verified" Subunit_of_a_possibly_tetrameric_trichostatin_A-sensitive_class_II_histone_deacetylase_complex_containing_an_Hda1p_homodimer_and_an_Hda2p-Hda3p_heterodimer;_involved_in_telomere_maintenance YDR296W MHR1 XTC1 mitochondrial_genome_maintenance transcription_regulator_activity nucleus* None None 4 1055209 1055889 YDR296W S000002704 "ORF,_Verified" Protein_involved_in_homologous_recombination_in_mitochondria_and_in_transcription_regulation_in_nucleus;_binds_to_activation_domains_of_acidic_activators;_required_for_recombination-dependent_mtDNA_partitioning YDR298C ATP5 OSC1 ATP_synthesis_coupled_proton_transport structural_molecule_activity* "proton-transporting_ATP_synthase,_stator_stalk_(sensu_Eukaryota)" None None 4 1058811 1058173 YDR298C S000002706 "ORF,_Verified" "Subunit_5_of_the_stator_stalk_of_mitochondrial_F1F0_ATP_synthase,_which_is_an_evolutionarily_conserved_enzyme_complex_required_for_ATP_synthesis;_homologous_to_bovine_subunit_OSCP_(oligomycin_sensitivity-conferring_protein);_phosphorylated" YDR299W BFR2 None ER_to_Golgi_transport molecular_function_unknown nucleolus None None 4 1059624 1061228 YDR299W S000002707 "ORF,_Verified" Essential_protein_possibly_involved_in_secretion;_multicopy_suppressor_of_sensitivity_to_Brefeldin_A YDR300C PRO1 None proline_biosynthesis glutamate_5-kinase_activity cytoplasm None None 4 1062788 1061502 YDR300C S000002708 "ORF,_Verified" "Gamma-glutamyl_kinase,_catalyzes_the_first_step_in_proline_biosynthesis" YDR301W CFT1 YHH1 mRNA_polyadenylylation* RNA_binding mitochondrion* None None 4 1063349 1067422 YDR301W S000002709 "ORF,_Verified" "RNA-binding_subunit_of_the_mRNA_cleavage_and_polyadenylation_factor;_involved_in_poly(A)_site_recognition_and_required_for_both_pre-mRNA_cleavage_and_polyadenylation,_51%_sequence_similarity_with_mammalian_AAUAA-binding_subunit_of_CPSF" YDR302W GPI11 None GPI_anchor_biosynthesis phosphoethanolamine_N-methyltransferase_activity endoplasmic_reticulum* S/G2 None 4 1067728 1068387 YDR302W S000002710 "ORF,_Verified" ER_membrane_protein_involved_in_a_late_step_of_glycosylphosphatidylinositol_(GPI)_anchor_assembly;_involved_in_the_addition_of_phosphoethanolamine_to_the_multiply_mannosylated_GPI_intermediate;_human_PIG-Fp_is_a_functional_homolog YDR303C RSC3 None "regulation_of_transcription,_DNA-dependent*" DNA_binding nucleus* None None 4 1071383 1068726 YDR303C S000002711 "ORF,_Verified" Component_of_the_RSC_chromatin_remodeling_complex;_essential_gene_required_for_maintenance_of_proper_ploidy_and_regulation_of_ribosomal_protein_genes_and_the_cell_wall/stress_response;_highly_similar_to_Rsc30p YDR304C CPR5 CYP5 biological_process_unknown peptidyl-prolyl_cis-trans_isomerase_activity cytoplasm* None None 4 1072554 1071877 YDR304C S000002712 "ORF,_Verified" "Peptidyl-prolyl_cis-trans_isomerase_(cyclophilin)_of_the_endoplasmic_reticulum,_catalyzes_the_cis-trans_isomerization_of_peptide_bonds_N-terminal_to_proline_residues;_transcriptionally_induced_in_response_to_unfolded_proteins_in_the_ER" YDR305C HNT2 APH1 nucleoside_catabolism hydrolase_activity* cytoplasm* None None 4 1073485 1072743 YDR305C S000002713 "ORF,_Verified" Dinucleoside_triphosphate_hydrolase;_has_similarity_to_the_tumor_suppressor_FHIT_and_belongs_to_the_histidine_triad_(HIT)_superfamily_of_nucleotide-binding_proteins YDR306C None None ubiquitin-dependent_protein_catabolism protein_binding ubiquitin_ligase_complex None None 4 1075168 1073732 YDR306C S000002714 "ORF,_Uncharacterized" F-box_protein_of_unknown_function;_interacts_with_Sgt1p_via_a_Leucine-Rich_Repeat_(LRR)_domain YDR307W None None biological_process_unknown molecular_function_unknown endoplasmic_reticulum G1 None 4 1075862 1077850 YDR307W S000002715 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YDR309C GIC2 None establishment_of_cell_polarity_(sensu_Fungi)* small_GTPase_regulator_activity bud_tip* G1 None 4 1080196 1079045 YDR309C S000002717 "ORF,_Verified" "Redundant_rho-like_GTPase_Cdc42p_effector;_homolog_of_Gic1p;_involved_in_initiation_of_budding_and_cellular_polarization;_interacts_with_Cdc42p_via_the_Cdc42/Rac-interactive_binding_(CRIB)_domain_and_with_PI(4,5)P2_via_a_polybasic_region" YDR310C SUM1 None chromatin_silencing_at_telomere* transcriptional_repressor_activity nucleus* None None 4 1084313 1081125 YDR310C S000002718 "ORF,_Verified" "Transcriptional_repressor_required_for_mitotic_repression_of_middle_sporulation-specific_genes;_also_acts_as_general_replication_initiation_factor;_involved_in_telomere_maintenance,_chromatin_silencing;_regulated_by_pachytene_checkpoint" YDR311W TFB1 None transcription_initiation_from_RNA_polymerase_II_promoter* general_RNA_polymerase_II_transcription_factor_activity transcription_factor_TFIIH_complex* None None 4 1085063 1086991 YDR311W S000002719 "ORF,_Verified" "Subunit_of_TFIIH_and_nucleotide_excision_repair_factor_3_complexes,_required_for_nucleotide_excision_repair,_target_for_transcriptional_activators" YDR312W SSF2 None ribosomal_large_subunit_assembly_and_maintenance* rRNA_binding nucleolus None None 4 1087579 1088940 YDR312W S000002720 "ORF,_Verified" "Protein_required_for_ribosomal_large_subunit_maturation,_functionally_redundant_with_Ssf1p;_member_of_the_Brix_family" YDR314C RAD34 None biological_process_unknown molecular_function_unknown nucleus None None 4 1092509 1090431 YDR314C S000002722 "ORF,_Verified" Protein_involved_in_nucleotide_excision_repair_(NER);_homologous_to_RAD4 YDR315C IPK1 GSL1 myo-inositol_metabolism inositol_or_phosphatidylinositol_kinase_activity nucleus None None 4 1093584 1092739 YDR315C S000002723 "ORF,_Verified" "Inositol_1,3,4,5,6-pentakisphosphate_2-kinase,_nuclear_protein_required_for_synthesis_of_1,2,3,4,5,6-hexakisphosphate_(phytate),_which_is_integral_to_cell_function;_has_2_motifs_conserved_in_other_fungi;_ipk1_gle1_double_mutant_is_inviable" YDR316W OMS1 None biological_process_unknown S-adenosylmethionine-dependent_methyltransferase_activity mitochondrion* None None 4 1093761 1095176 YDR316W S000002724 "ORF,_Verified" Protein_integral_to_the_mitochondrial_membrane;_has_a_conserved_methyltransferase_motif;_multicopy_suppressor_of_respiratory_defects_caused_by_OXA1_mutations YDR316W-A None None None None None None None 4 1096062 1097384 YDR316W-A S000007398 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YDR316W-B None None None None None None None 4 1096062 1101330 YDR316W-B S000007399 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YDR318W MCM21 CTF5 chromosome_segregation protein_binding condensed_nuclear_chromosome_kinetochore* None None 4 1103756 1104945 YDR318W S000002726 "ORF,_Verified" "Protein_involved_in_minichromosome_maintenance;_component_of_the_COMA_complex_(Ctf19p,_Okp1p,_Mcm21p,_Ame1p)_that_bridges_kinetochore_subunits_that_are_in_contact_with_centromeric_DNA_and_the_subunits_bound_to_microtubules" YDR319C None FIT2A biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1105825 1105001 YDR319C S000002727 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_identified_as_an_ortholog_of_the_highly_conserved_FIT_family_of_proteins_involved_in_triglyceride_droplet_biosynthesis;_interacts_with_Sst2p_and_Hsp82p_in_high-throughput_two-hybrid_screens" YDR320C SWA2 BUD24|AUX1 ER_organization_and_biogenesis protein_binding endoplasmic_reticulum_membrane None None 4 1108099 1106093 YDR320C S000002728 "ORF,_Verified" Auxilin-like_protein_involved_in_vesicular_transport;_clathrin-binding_protein_required_for_uncoating_of_clathrin-coated_vesicles YDR321W ASP1 None asparagine_catabolism asparaginase_activity cytosol* None None 4 1108700 1109845 YDR321W S000002729 "ORF,_Verified" "Cytosolic_L-asparaginase,_involved_in_asparagine_catabolism" YDR322C-A TIM11 ATP21 ATP_synthesis_coupled_proton_transport structural_molecule_activity "proton-transporting_ATP_synthase_complex,_coupling_factor_F(o)_(sensu_Eukaryota)" None None 4 1112291 1112001 YDR322C-A S000007255 "ORF,_Verified" "Subunit_e_of_mitochondrial_F1F0-ATPase,_which_is_a_large,_evolutionarily_conserved_enzyme_complex_required_for_ATP_synthesis;_essential_for_the_dimeric_and_oligomeric_state_of_ATP_synthase" YDR322W MRPL35 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 4 1110587 1111690 YDR322W S000002730 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YDR323C PEP7 VPT19|VPS19|VPL21|VAC1 vesicle_fusion* molecular_function_unknown cytoplasm* None None 4 1114025 1112478 YDR323C S000002731 "ORF,_Verified" "Multivalent_adaptor_protein_that_facilitates_vesicle-mediated_vacuolar_protein_sorting_by_ensuring_high-fidelity_vesicle_docking_and_fusion,_which_are_essential_for_targeting_of_vesicles_to_the_endosome;_required_for_vacuole_inheritance" YDR324C UTP4 None processing_of_20S_pre-rRNA snoRNA_binding small_nucleolar_ribonucleoprotein_complex None None 4 1116761 1114431 YDR324C S000002732 "ORF,_Verified" Subunit_of_U3-containing_90S_preribosome_and_Small_Subunit_(SSU)_processome_complexes_involved_in_production_of_18S_rRNA_and_assembly_of_small_ribosomal_subunit;_member_of_t-Utp_subcomplex_involved_with_transcription_of_35S_rRNA_transcript YDR325W YCG1 YCS5|TIE1 mitotic_sister_chromatid_segregation* molecular_function_unknown nuclear_condensin_complex None None 4 1117122 1120229 YDR325W S000002733 "ORF,_Verified" "Non-SMC_subunit_of_the_condensin_complex_(Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p);_required_for_establishment_and_maintenance_of_chromosome_condensation,_chromosome_segregation_and_for_chromatin_binding_of_the_condensin_complex" YDR326C YSP2 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1124921 1120605 YDR326C S000002734 "ORF,_Verified" Protein_involved_in_programmed_cell_death;_mutant_shows_resistance_to_cell_death_induced_by_amiodarone_or_intracellular_acidification YDR328C SKP1 CBF3D|MGO1 protein_complex_assembly* protein_binding* cytoplasm* None None 4 1126014 1125430 YDR328C S000002736 "ORF,_Verified" "Evolutionarily_conserved_kinetochore_protein_that_is_part_of_multiple_protein_complexes,_including_the_SCF_ubiquitin_ligase_complex,_the_CBF3_complex_that_binds_centromeric_DNA,_and_the_RAVE_complex_that_regulates_assembly_of_the_V-ATPase" YDR329C PEX3 PAS3 peroxisome_organization_and_biogenesis* protein_binding peroxisomal_membrane None None 4 1127591 1126266 YDR329C S000002737 "ORF,_Verified" Peroxisomal_membrane_protein_(PMP)_required_required_for_the_proper_localization_and_stability_of_PMPs;_interacts_with_Pex19p YDR330W UBX5 None ubiquitin-dependent_protein_catabolism molecular_function_unknown cytoplasm* None Up 4 1127868 1129370 YDR330W S000002738 "ORF,_Verified" UBX_(ubiquitin_regulatory_X)_domain-containing_protein_that_interacts_with_Cdc48p YDR331W GPI8 None attachment_of_GPI_anchor_to_protein GPI-anchor_transamidase_activity GPI-anchor_transamidase_complex None None 4 1129584 1130819 YDR331W S000002739 "ORF,_Verified" ER_membrane_glycoprotein_subunit_of_the_glycosylphosphatidylinositol_transamidase_complex_that_adds_glycosylphosphatidylinositol_(GPI)_anchors_to_newly_synthesized_proteins;_human_PIG-K_protein_is_a_functional_homolog YDR332W IRC3 None biological_process_unknown helicase_activity mitochondrion None None 4 1130997 1133066 YDR332W S000002740 "ORF,_Verified" Putative_protein_of_unknown_function;_null_mutant_displays_increased_levels_of_spontaneous_Rad52p_foci;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_mitochondrion YDR333C None None biological_process_unknown molecular_function_unknown cytoplasm None None 4 1135427 1133256 YDR333C S000002741 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YDR335W MSN5 STE21|KAP142 protein_export_from_nucleus protein_binding* nucleus None None 4 1141163 1144837 YDR335W S000002743 "ORF,_Verified" "Karyopherin_involved_in_nuclear_import_and_export;_shown_to_be_responsible_for_nuclear_import_of_replication_protein_A_and_for_export_of_several_proteins_including_Swi6p,_Far1p,_and_Pho4p;_cargo_dissociation_involves_binding_to_RanGTP" YDR336W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1145087 1146031 YDR336W S000002744 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_sumoylated_under_stress_conditions_in_a_genome_wide_study;_YDR336W_is_not_an_essential_gene YDR337W MRPS28 None protein_biosynthesis* structural_constituent_of_ribosome* mitochondrial_small_ribosomal_subunit G2/M None 4 1146314 1147174 YDR337W S000002745 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YDR338C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1149461 1147374 YDR338C S000002746 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YDR339C FCF1 UTP24 biological_process_unknown* molecular_function_unknown cellular_component_unknown None None 4 1150515 1149946 YDR339C S000002747 "ORF,_Verified" Putative_PINc_domain_nuclease_required_for_early_cleavages_of_35S_pre-rRNA_and_maturation_of_18S_rRNA;_component_of_the_SSU_(small_subunit)_processome_involved_in_40S_ribosomal_subunit_biogenesis;_copurifies_with_Faf1p YDR341C None RRS1 protein_biosynthesis arginine-tRNA_ligase_activity cytoplasm* None None 4 1153621 1151798 YDR341C S000002749 "ORF,_Verified" "Arginyl-tRNA_synthetase,_proposed_to_be_cytoplasmic_but_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YDR342C HXT7 None hexose_transport glucose_transporter_activity* mitochondrion* M/G1 None 4 1155923 1154211 YDR342C S000002750 "ORF,_Verified" "High-affinity_glucose_transporter_of_the_major_facilitator_superfamily,_nearly_identical_to_Hxt6p,_expressed_at_high_basal_levels_relative_to_other_HXTs,_expression_repressed_by_high_glucose_levels" YDR343C HXT6 None hexose_transport glucose_transporter_activity* mitochondrion* None None 4 1161315 1159603 YDR343C S000002751 "ORF,_Verified" "High-affinity_glucose_transporter_of_the_major_facilitator_superfamily,_nearly_identical_to_Hxt7p,_expressed_at_high_basal_levels_relative_to_other_HXTs,_repression_of_expression_by_high_glucose_requires_SNF3" YDR345C HXT3 None hexose_transport glucose_transporter_activity* plasma_membrane None None 4 1164655 1162952 YDR345C S000002753 "ORF,_Verified" "Low_affinity_glucose_transporter_of_the_major_facilitator_superfamily,_expression_is_induced_in_low_or_high_glucose_conditions" YDR347W MRP1 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 4 1169173 1170138 YDR347W S000002755 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_small_subunit;_MRP1_exhibits_genetic_interactions_with_PET122,_encoding_a_COX3-specific_translational_activator,_and_with_PET123,_encoding_a_small_subunit_mitochondrial_ribosomal_protein" YDR348C None None biological_process_unknown molecular_function_unknown bud_neck None None 4 1171820 1170321 YDR348C S000002756 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cell_periphery_and_bud_neck;_potential_Cdc28p_substrate YDR349C YPS7 None biological_process_unknown aspartic-type_endopeptidase_activity cytoplasm* None None 4 1174171 1172381 YDR349C S000002757 "ORF,_Verified" "Putative_GPI-anchored_aspartic_protease,_located_in_the_cytoplasm_and_endoplasmic_reticulum" YDR350C ATP22 TCM10 protein_complex_assembly molecular_function_unknown mitochondrial_inner_membrane None None 4 1178168 1176333 YDR350C S000002758 "ORF,_Verified" "Mitochondrial_inner_membrane_protein_required_for_assembly_of_the_F0_sector_of_mitochondrial_F1F0_ATP_synthase,_which_is_a_large,_evolutionarily_conserved_enzyme_complex_required_for_ATP_synthesis" YDR351W SBE2 None cell_wall_organization_and_biogenesis molecular_function_unknown Golgi_apparatus None None 4 1178660 1181254 YDR351W S000002759 "ORF,_Verified" Protein_involved_in_the_transport_of_cell_wall_components_from_the_Golgi_to_the_cell_surface;_required_for_bud_growth YDR352W None None biological_process_unknown molecular_function_unknown vacuolar_membrane_(sensu_Fungi) None None 4 1181795 1182748 YDR352W S000002760 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YDR353W TRR1 None regulation_of_cell_redox_homeostasis thioredoxin-disulfide_reductase_activity cytoplasm G1 None 4 1183293 1184252 YDR353W S000002761 "ORF,_Verified" "Cytoplasmic_thioredoxin_reductase,_key_regulatory_enzyme_that_determines_the_redox_state_of_the_thioredoxin_system,_which_acts_as_a_disulfide_reductase_system_and_protects_cells_against_both_oxidative_and_reductive_stress" YDR354W TRP4 None tryptophan_biosynthesis anthranilate_phosphoribosyltransferase_activity cytoplasm* None Up 4 1184741 1185883 YDR354W S000002762 "ORF,_Verified" "Anthranilate_phosphoribosyl_transferase_of_the_tryptophan_biosynthetic_pathway,_catalyzes_the_phosphoribosylation_of_anthranilate,_subject_to_the_general_control_system_of_amino_acid_biosynthesis" YDR356W SPC110 NUF1|XCM1 microtubule_nucleation structural_constituent_of_cytoskeleton inner_plaque_of_spindle_pole_body* G1 None 4 1186101 1188935 YDR356W S000002764 "ORF,_Verified" "Inner_plaque_spindle_pole_body_(SPB)_component,_ortholog_of_human_kendrin;_involved_in_connecting_nuclear_microtubules_to_SPB;_interacts_with_Tub4p-complex_and_calmodulin;_phosphorylated_by_Mps1p_in_cell_cycle-dependent_manner" YDR357C None None biological_process_unknown molecular_function_unknown cytoplasm None None 4 1189561 1189193 YDR357C S000002765 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern YDR358W GGA1 None Golgi_to_vacuole_transport* ubiquitin_binding Golgi_trans_face None Up 4 1190053 1191726 YDR358W S000002766 "ORF,_Verified" "Golgi-localized_protein_with_homology_to_gamma-adaptin,_interacts_with_and_regulates_Arf1p_and_Arf2p_in_a_GTP-dependent_manner_in_order_to_facilitate_traffic_through_the_late_Golgi" YDR359C EAF1 VID21 chromatin_modification molecular_function_unknown histone_acetyltransferase_complex* None None 4 1194878 1191930 YDR359C S000002767 "ORF,_Verified" "Component_of_the_NuA4_histone_acetyltransferase_complex;_required_for_initiation_of_pre-meiotic_DNA_replication,_probably_due_to_its_requirement_for_significant_expression_of_IME1" YDR361C BCP1 None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 1196256 1195405 YDR361C S000002769 "ORF,_Verified" "Essential_protein_involved_in_nuclear_export_of_Mss4p,_which_is_a_lipid_kinase_that_generates_phosphatidylinositol_4,5-biphosphate_and_plays_a_role_in_actin_cytoskeleton_organization_and_vesicular_transport" YDR362C TFC6 None transcription_initiation_from_RNA_polymerase_III_promoter RNA_polymerase_III_transcription_factor_activity transcription_factor_TFIIIC_complex None None 4 1198690 1196672 YDR362C S000002770 "ORF,_Verified" One_of_six_subunits_of_RNA_polymerase_III_transcription_initiation_factor_complex_(TFIIIC);_part_of_TFIIIC_TauB_domain_that_binds_BoxB_promoter_sites_of_tRNA_and_other_genes;_cooperates_with_Tfc3p_in_DNA_binding;_human_homolog_is_TFIIIC-110 YDR363W ESC2 None chromatin_silencing_at_silent_mating-type_cassette molecular_function_unknown nucleus None None 4 1199176 1200546 YDR363W S000002771 "ORF,_Verified" "Protein_involved_in_mating-type_locus_silencing,_interacts_with_Sir2p;_probably_functions_to_recruit_or_stabilize_Sir_proteins" YDR363W-A SEM1 HOD1|DSS1 ubiquitin-dependent_protein_catabolism* molecular_function_unknown nucleus* None None 4 1202121 1202390 YDR363W-A S000007235 "ORF,_Verified" Component_of_the_lid_subcomplex_of_the_regulatory_subunit_of_the_26S_proteasome;_ortholog_of_human_DSS1 YDR364C CDC40 SLU4|SLT15|PRP17 "nuclear_mRNA_splicing,_via_spliceosome*" "RNA_splicing_factor_activity,_transesterification_mechanism*" nuclear_pore* None None 4 1204203 1202836 YDR364C S000002772 "ORF,_Verified" "Pre-mRNA_splicing_factor,_important_for_catalytic_step_II_of_pre-mRNA_splicing_and_plays_a_role_in_cell_cycle_progression;_required_for_DNA_synthesis_during_mitosis_and_meiosis;_has_WD_repeats" YDR365C ESF1 None rRNA_processing RNA_binding nucleus* None None 4 1206376 1204490 YDR365C S000002773 "ORF,_Verified" Nucleolar_protein_involved_in_pre-rRNA_processing;_depletion_causes_severely_decreased_18S_rRNA_levels YDR365W-A None None None None None None None 4 1206990 1208312 YDR365W-A S000007400 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YDR365W-B None None None None None None None 4 1206990 1212258 YDR365W-B S000007401 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YDR366C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1212829 1212431 YDR366C S000002774 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YDR367W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 1212841 1213607 YDR367W S000002775 "ORF,_Uncharacterized" Component_of_the_inositol_phosphorylceramide_synthase;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern YDR368W YPR1 None arabinose_catabolism* oxidoreductase_activity* cytoplasm* G1 None 4 1213897 1214835 YDR368W S000002776 "ORF,_Verified" "2-methylbutyraldehyde_reductase,_may_be_involved_in_isoleucine_catabolism" YDR369C XRS2 None double-strand_break_repair_via_nonhomologous_end-joining* protein_binding* nucleus* None None 4 1217573 1215009 YDR369C S000002777 "ORF,_Verified" "Protein_required_for_DNA_repair;_component_of_the_Mre11_complex,_which_is_involved_in_double_strand_breaks,_meiotic_recombination,_telomere_maintenance,_and_checkpoint_signaling" YDR370C None None biological_process_unknown molecular_function_unknown cytoplasm None None 4 1219103 1217775 YDR370C S000002778 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YDR371W CTS2 None biological_process_unknown molecular_function_unknown cytoplasm None None 4 1219406 1220941 YDR371W S000002779 "ORF,_Uncharacterized" Sporulation-specific_chitinase YDR372C VPS74 API1 protein_targeting_to_vacuole molecular_function_unknown cytoplasm* None None 4 1222142 1221105 YDR372C S000002780 "ORF,_Verified" Protein_required_for_Golgi_localization_of_glycosyltransferases;_binds_the_cytosolic_domains_of_Golgi_glycosyltransferases;_functions_as_a_heterotetramer YDR373W FRQ1 None regulation_of_signal_transduction enzyme_activator_activity* membrane None None 4 1222752 1223324 YDR373W S000002781 "ORF,_Verified" N-myristoylated_calcium-binding_protein_that_may_have_a_role_in_intracellular_signaling_through_its_regulation_of_the_phosphatidylinositol_4-kinase_Pik1p;_member_of_the_recoverin/frequenin_branch_of_the_EF-hand_superfamily YDR375C BCS1 None aerobic_respiration* ATPase_activity mitochondrial_inner_membrane None None 4 1226529 1225159 YDR375C S000002783 "ORF,_Verified" "Protein_of_the_mitochondrial_inner_membrane_that_functions_as_an_ATP-dependent_chaperone,_required_for_the_incorporation_of_the_Rip1p_and_Qcr10p_subunits_into_the_cytochrome_bc(1)_complex;_member_of_the_CDC48/PAS1/SEC18_ATPase_family" YDR378C LSM6 None "nuclear_mRNA_splicing,_via_spliceosome*" RNA_binding* nucleolus* None None 4 1229602 1229342 YDR378C S000002786 "ORF,_Verified" "Lsm_(Like_Sm)_protein;_part_of_heteroheptameric_complexes_(Lsm2p-7p_and_either_Lsm1p_or_8p):_cytoplasmic_Lsm1p_complex_involved_in_mRNA_decay;_nuclear_Lsm8p_complex_part_of_U6_snRNP_and_possibly_involved_in_processing_tRNA,_snoRNA,_and_rRNA" YDR379W RGA2 None actin_filament_organization* signal_transducer_activity* intracellular None None 4 1230160 1233189 YDR379W S000002787 "ORF,_Verified" "GTPase-activating_protein_for_the_polarity-establishment_protein_Cdc42p;_implicated_in_control_of_septin_organization,_pheromone_response,_and_haploid_invasive_growth;_regulated_by_Pho85p_and_Cdc28p" YDR380W ARO10 None leucine_catabolism* pyruvate_decarboxylase_activity* cytoplasm G2/M None 4 1234211 1236118 YDR380W S000002788 "ORF,_Verified" "Phenylpyruvate_decarboxylase,_catalyzes_decarboxylation_of_phenylpyruvate_to_phenylacetaldehyde,_which_is_the_first_specific_step_in_the_Ehrlich_pathway" YDR381W YRA1 SHE11 mRNA_export_from_nucleus RNA_binding transcription_export_complex None None 4 1236551 1237997 YDR381W S000002789 "ORF,_Verified" "Nuclear_protein_that_binds_to_RNA_and_to_Mex67p,_required_for_export_of_poly(A)+_mRNA_from_the_nucleus;_member_of_the_REF_(RNA_and_export_factor_binding_proteins)_family;_another_family_member,_Yra2p,_can_substitute_for_Yra1p_function" YDR382W RPP2B YPA1|RPL45 translational_elongation* structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 4 1239485 1239817 YDR382W S000002790 "ORF,_Verified" "Ribosomal_protein_P2_beta,_a_component_of_the_ribosomal_stalk,_which_is_involved_in_the_interaction_between_translational_elongation_factors_and_the_ribosome;_regulates_the_accumulation_of_P1_(Rpp1Ap_and_Rpp1Bp)_in_the_cytoplasm" YDR385W EFT2 None translational_elongation translation_elongation_factor_activity ribosome None None 4 1243223 1245751 YDR385W S000002793 "ORF,_Verified" "Elongation_factor_2_(EF-2),_also_encoded_by_EFT1;_catalyzes_ribosomal_translocation_during_protein_synthesis;_contains_diphthamide,_the_unique_posttranslationally_modified_histidine_residue_specifically_ADP-ribosylated_by_diphtheria_toxin" YDR387C None None biological_process_unknown permease_activity cellular_component_unknown None None 4 1249814 1248147 YDR387C S000002795 "ORF,_Uncharacterized" "Putative_transporter,_member_of_the_sugar_porter_family;_YDR387C_is_not_an_essential_gene" YDR388W RVS167 None endocytosis* cytoskeletal_protein_binding actin_cortical_patch None None 4 1250179 1251627 YDR388W S000002796 "ORF,_Verified" "Actin-associated_protein,_subunit_of_a_complex_(Rvs161p-Rvs167p)_involved_in_regulation_of_actin_cytoskeleton,_endocytosis,_and_viability_following_starvation_or_osmotic_stress;_homolog_of_mammalian_amphiphysin" YDR391C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 1258049 1257351 YDR391C S000002799 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_possibly_involved_in_zinc_homeostasis;_Bdf1p-dependent_transcription_induced_by_salt_stress;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_both_the_cytoplasm_and_the_nucleus" YDR393W SHE9 MDM33 mitochondrion_organization_and_biogenesis* molecular_function_unknown mitochondrial_inner_membrane None None 4 1259894 1261264 YDR393W S000002801 "ORF,_Verified" "Mitochondrial_inner_membrane_protein_required_for_normal_mitochondrial_morphology,_may_be_involved_in_fission_of_the_inner_membrane;_forms_a_homo-oligomeric_complex" YDR394W RPT3 YTA2|YNT1 ubiquitin-dependent_protein_catabolism ATPase_activity* "proteasome_regulatory_particle,_base_subcomplex_(sensu_Eukaryota)" None None 4 1261674 1262960 YDR394W S000002802 "ORF,_Verified" One_of_six_ATPases_of_the_19S_regulatory_particle_of_the_26S_proteasome_involved_in_the_degradation_of_ubiquitinated_substrates;_substrate_of_N-acetyltransferase_B YDR395W SXM1 KAP108 mRNA_export_from_nucleus* protein_carrier_activity nucleus None None 4 1263317 1266151 YDR395W S000002803 "ORF,_Verified" "Nuclear_transport_factor_(karyopherin)_involved_in_protein_transport_between_the_cytoplasm_and_nucleoplasm;_similar_to_Nmd5p,_Cse1p,_Lph2p,_and_the_human_cellular_apoptosis_susceptibility_protein,_CAS1" YDR397C NCB2 YDR1 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter transcription_corepressor_activity nucleus None None 4 1266891 1266359 YDR397C S000002805 "ORF,_Verified" Subunit_of_a_heterodimeric_NC2_transcription_regulator_complex_with_Bur6p;_complex_binds_to_TBP_and_can_repress_transcription_by_preventing_preinitiation_complex_assembly_or_stimulate_activated_transcription;_homologous_to_human_NC2beta YDR399W HPT1 HPRT|BRA6 purine_nucleotide_biosynthesis hypoxanthine_phosphoribosyltransferase_activity cytoplasm* None Down 4 1270061 1270726 YDR399W S000002807 "ORF,_Verified" "Dimeric_hypoxanthine-guanine_phosphoribosyltransferase,_catalyzes_the_formation_of_both_inosine_monophosphate_and_guanosine_monophosphate;_mutations_in_the_human_homolog_HPRT1_can_cause_Lesch-Nyhan_syndrome_and_Kelley-Seegmiller_syndrome" YDR404C RPB7 None transcription_from_RNA_polymerase_II_promoter DNA-directed_RNA_polymerase_activity "DNA-directed_RNA_polymerase_II,_core_complex" None None 4 1277162 1276647 YDR404C S000002812 "ORF,_Verified" RNA_polymerase_II_subunit_B16;_forms_two_subunit_dissociable_complex_with_Rpb4p YDR405W MRP20 MRPL41 protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 4 1277639 1278430 YDR405W S000002813 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YDR406W PDR15 None transport "ATPase_activity,_coupled_to_transmembrane_movement_of_substances" integral_to_membrane None None 4 1279203 1283792 YDR406W S000002814 "ORF,_Verified" "Plasma_membrane_ATP_binding_cassette_(ABC)_transporter,_multidrug_transporter_and_general_stress_response_factor_implicated_in_cellular_detoxification;_regulated_by_Pdr1p,_Pdr3p_and_Pdr8p;_promoter_contains_a_PDR_responsive_element" YDR410C STE14 None peptide_pheromone_maturation protein-S-isoprenylcysteine_O-methyltransferase_activity endoplasmic_reticulum_membrane None None 4 1293084 1292365 YDR410C S000002818 "ORF,_Verified" "Farnesyl_cysteine-carboxyl_methyltransferase,_mediates_the_carboxyl_methylation_step_during_C-terminal_CAAX_motif_processing_of_a-factor_and_RAS_proteins_in_the_endoplasmic_reticulum,_localizes_to_the_ER_membrane" YDR411C DFM1 None biological_process_unknown* molecular_function_unknown endoplasmic_reticulum None None 4 1294387 1293362 YDR411C S000002819 "ORF,_Verified" ER_localized_derlin-like_family_member_involved_in_ER_stress_and_homeostasis;_not_involved_in_ERAD_or_substrate_retrotranslocation;_interacts_with_CDC48;_contains_four_transmembrane_domains_and_two_SHP_boxes YDR412W RRP17 None rRNA_processing molecular_function_unknown cytoplasm None None 4 1294686 1295393 YDR412W S000002820 "ORF,_Uncharacterized" Component_of_the_pre-60S_pre-ribosomal_particle;_required_for_cell_viability YDR418W RPL12B None protein_biosynthesis* structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 4 1301609 1302106 YDR418W S000002826 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl12Ap;_rpl12a_rpl12b_double_mutant_exhibits_slow_growth_and_slow_translation;_has_similarity_to_E._coli_L11_and_rat_L12_ribosomal_proteins" YDR419W RAD30 DBH1 DNA_repair* eta_DNA_polymerase_activity replication_fork None None 4 1303167 1305065 YDR419W S000002827 "ORF,_Verified" "DNA_polymerase_eta,_involved_in_the_predominantly_error-free_bypass_replication_of_DNA_lesions,_catalyzes_the_efficient_and_accurate_synthesis_of_DNA_opposite_cyclobutane_pyrimidine_dimers;_homolog_of_human_POLH_and_bacterial_DinB_proteins" YDR420W HKR1 None cell_wall_organization_and_biogenesis* molecular_function_unknown plasma_membrane None None 4 1306260 1311668 YDR420W S000002828 "ORF,_Verified" "Serine/threonine_rich_cell_surface_protein;_osmosensor;_involved_in_the_regulation_of_cell_wall_beta-1,3_glucan_synthesis,_bud_site_selection_and_hyperosmotic_response;_overexpression_confers_resistance_to_Hansenula_mrakii_killer_toxin_HM-1" YDR421W ARO80 None positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* specific_RNA_polymerase_II_transcription_factor_activity nucleus None None 4 1312033 1314885 YDR421W S000002829 "ORF,_Verified" Zinc_finger_transcriptional_activator_of_the_Zn2Cys6_family;_activates_transcription_of_aromatic_amino_acid_catabolic_genes_in_the_presence_of_aromatic_amino_acids YDR427W RPN9 None ubiquitin-dependent_protein_catabolism structural_molecule_activity "proteasome_regulatory_particle,_lid_subcomplex_(sensu_Eukaryota)" None None 4 1322198 1323379 YDR427W S000002835 "ORF,_Verified" "Non-ATPase_regulatory_subunit_of_the_26S_proteasome,_has_similarity_to_putative_proteasomal_subunits_in_other_species;_null_mutant_is_temperature_sensitive_and_exhibits_cell_cycle_and_proteasome_assembly_defects" YDR428C BNA7 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1324232 1323447 YDR428C S000002836 "ORF,_Verified" "Formylkynurenine_formamidase,_involved_in_the_de_novo_biosynthesis_of_NAD_from_tryptophan_via_kynurenine" YDR432W NPL3 NAB1|NOP3|MTS1|MTR13 mRNA_export_from_nucleus mRNA_binding* cytoplasm* G2/M None 4 1328776 1330020 YDR432W S000002840 "ORF,_Verified" RNA-binding_protein_that_carries_poly(A)+_mRNA_from_the_nucleus_into_the_cytoplasm;_dissociation_from_mRNAs_is_promoted_by_Mtr10p;_phosphorylated_by_Sky1p_in_the_cytoplasm YDR434W GPI17 None attachment_of_GPI_anchor_to_protein GPI-anchor_transamidase_activity GPI-anchor_transamidase_complex None None 4 1331230 1332834 YDR434W S000002842 "ORF,_Verified" Transmembrane_protein_subunit_of_the_glycosylphosphatidylinositol_transamidase_complex_that_adds_GPIs_to_newly_synthesized_proteins;_human_PIG-Sp_homolog YDR435C PPM1 None C-terminal_protein_amino_acid_methylation C-terminal_protein_carboxyl_methyltransferase_activity cellular_component_unknown None None 4 1333962 1332976 YDR435C S000002843 "ORF,_Verified" "Carboxyl_methyltransferase,_methylates_the_C_terminus_of_the_protein_phosphatase_2A_catalytic_subunit_(Pph21p_or_Pph22p),_which_is_important_for_complex_formation_with_regulatory_subunits" YDR436W PPZ2 None sodium_ion_homeostasis protein_serine/threonine_phosphatase_activity cellular_component_unknown None None 4 1334814 1336946 YDR436W S000002844 "ORF,_Verified" "Serine/threonine_protein_phosphatase_Z,_isoform_of_Ppz1p;_involved_in_regulation_of_potassium_transport,_which_affects_osmotic_stability,_cell_cycle_progression,_and_halotolerance" YDR441C APT2 None biological_process_unknown molecular_function_unknown* cytoplasm None None 4 1345055 1344510 YDR441C S000002849 "ORF,_Verified" "Apparent_pseudogene,_not_transcribed_or_translated_under_normal_conditions;_encodes_a_protein_with_similarity_to_adenine_phosphoribosyltransferase,_but_artificially_expressed_protein_exhibits_no_enzymatic_activity" YDR443C SSN2 MED13|RYE3|UME2|SRB9|SCA1|NUT8 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter general_RNA_polymerase_II_transcription_factor_activity transcription_factor_complex None None 4 1349931 1345669 YDR443C S000002851 "ORF,_Verified" Subunit_of_the_RNA_polymerase_II_mediator_complex;_associates_with_core_polymerase_subunits_to_form_the_RNA_polymerase_II_holoenzyme;_required_for_stable_association_of_Srb10p-Srb11p_kinase;_essential_for_transcriptional_regulation YDR444W None None biological_process_unknown molecular_function_unknown cytoplasm None None 4 1350283 1352346 YDR444W S000002852 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YDR447C RPS17B RPL51B|RP51B protein_biosynthesis* structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 4 1355546 1354822 YDR447C S000002855 "ORF,_Verified" Ribosomal_protein_51_(rp51)_of_the_small_(40s)_subunit;_nearly_identical_to_Rps17Ap_and_has_similarity_to_rat_S17_ribosomal_protein YDR448W ADA2 SWI8 histone_acetylation* transcription_coactivator_activity SAGA_complex* S None 4 1356058 1357362 YDR448W S000002856 "ORF,_Verified" "Transcription_coactivator,_component_of_the_ADA_and_SAGA_transcriptional_adaptor/HAT_(histone_acetyltransferase)_complexes" YDR449C UTP6 None processing_of_20S_pre-rRNA snoRNA_binding small_nucleolar_ribonucleoprotein_complex None None 4 1358895 1357573 YDR449C S000002857 "ORF,_Verified" "Nucleolar_protein,_component_of_the_small_subunit_(SSU)_processome_containing_the_U3_snoRNA_that_is_involved_in_processing_of_pre-18S_rRNA" YDR450W RPS18A None protein_biosynthesis structural_constituent_of_ribosome mitochondrion* None None 4 1359916 1360791 YDR450W S000002858 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps18Bp_and_has_similarity_to_E._coli_S13_and_rat_S18_ribosomal_proteins YDR451C YHP1 None negative_regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nuclear_chromosome S None 4 1362174 1361113 YDR451C S000002859 "ORF,_Verified" "One_of_two_homeobox_transcriptional_repressors_(see_also_Yox1p),_that_bind_to_Mcm1p_and_to_early_cell_cycle_box_(ECB)_elements_of_cell_cycle_regulated_genes,_thereby_restricting_ECB-mediated_transcription_to_the_M/G1_interval" YDR453C TSA2 None regulation_of_cell_redox_homeostasis thioredoxin_peroxidase_activity cytoplasm None None 4 1365655 1365065 YDR453C S000002861 "ORF,_Verified" "Stress_inducible_cytoplasmic_thioredoxin_peroxidase;_cooperates_with_Tsa1p_in_the_removal_of_reactive_oxygen,_nitrogen_and_sulfur_species_using_thioredoxin_as_hydrogen_donor;_deletion_enhances_the_mutator_phenotype_of_tsa1_mutants" YDR454C GUK1 PUR5 GMP_metabolism guanylate_kinase_activity cytoplasm* None None 4 1366820 1366257 YDR454C S000002862 "ORF,_Verified" "Guanylate_kinase,_converts_GMP_to_GDP;_required_for_growth_and_mannose_outer_chain_elongation_of_cell_wall_N-linked_glycoproteins" YDR456W NHX1 VPL27|NHA2|VPS44 vacuolar_acidification* monovalent_inorganic_cation_transporter_activity late_endosome None None 4 1367478 1369379 YDR456W S000002864 "ORF,_Verified" "Endosomal_Na+/H+_exchanger,_required_for_intracellular_sequestration_of_Na+;_required_for_osmotolerance_to_acute_hypertonic_shock" YDR457W TOM1 None protein_monoubiquitination* ubiquitin-protein_ligase_activity nucleus* None None 4 1369783 1379589 YDR457W S000002865 "ORF,_Verified" E3_ubiquitin_ligase_of_the_hect-domain_class;_has_a_role_in_mRNA_export_from_the_nucleus_and_may_regulate_transcriptional_coactivators YDR458C HEH2 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1382039 1380048 YDR458C S000002866 "ORF,_Verified" "Inner_nuclear_membrane_(INM)_protein;_contains_helix-extension-helix_(HEH)_motif,_nuclear_localization_signal_sequence;_targeting_to_the_INM_requires_the_Srp1p-Kap95p_karyopherins_and_the_Ran_cycle" YDR459C PFA5 None protein_amino_acid_palmitoylation protein-cysteine_S-palmitoleyltransferase_activity cellular_component_unknown None None 4 1383436 1382312 YDR459C S000002867 "ORF,_Verified" Palmitoyltransferase_with_autoacylation_activity;_likely_functions_in_pathway(s)_outside_Ras;_member_of_a_family_of_putative_palmitoyltransferases_containing_an_Asp-His-His-Cys-cysteine_rich_(DHHC-CRD)_domain YDR460W TFB3 RIG2 transcription_initiation_from_RNA_polymerase_II_promoter* general_RNA_polymerase_II_transcription_factor_activity transcription_factor_TFIIH_complex* None None 4 1383804 1384769 YDR460W S000002868 "ORF,_Verified" "Subunit_of_TFIIH_and_nucleotide_excision_repair_factor_3_complexes,_involved_in_transcription_initiation,_required_for_nucleotide_excision_repair;_ring_finger_protein_similar_to_mammalian_CAK_and_TFIIH_subunit" YDR461W MFA1 None signal_transduction_during_conjugation_with_cellular_fusion mating_pheromone_activity soluble_fraction* G1 None 4 1385169 1385279 YDR461W S000002869 "ORF,_Verified" "Mating_pheromone_a-factor,_made_by_a_cells;_interacts_with_alpha_cells_to_induce_cell_cycle_arrest_and_other_responses_leading_to_mating;_biogenesis_involves_C-terminal_modification,_N-terminal_proteolysis,_and_export;_also_encoded_by_MFA2" YDR462W MRPL28 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 4 1386066 1386509 YDR462W S000002870 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YDR466W PKH3 None MAPKKK_cascade_during_cell_wall_biogenesis protein_kinase_activity cellular_component_unknown None None 4 1395114 1397810 YDR466W S000002874 "ORF,_Verified" "Protein_kinase_with_similarity_to_mammalian_phosphoinositide-dependent_kinase_1_(PDK1)_and_yeast_Pkh1p_and_Pkh2p,_two_redundant_upstream_activators_of_Pkc1p;_identified_as_a_multicopy_suppressor_of_a_pkh1_pkh2_double_mutant" YDR469W SDC1 SAF19|CPS25 chromatin_silencing_at_telomere* histone_lysine_N-methyltransferase_activity_(H3-K4_specific) COMPASS_complex None None 4 1399008 1399535 YDR469W S000002877 "ORF,_Verified" "Subunit_of_the_COMPASS_(Set1C)_complex,_which_methylates_histone_H3_on_lysine_4_and_is_required_in_transcriptional_silencing_near_telomeres;_has_similarity_to_C._elegans_Dpy-30" YDR471W RPL27B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 4 1401763 1402557 YDR471W S000002879 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl27Ap_and_has_similarity_to_rat_L27_ribosomal_protein" YDR473C PRP3 RNA3 "nuclear_mRNA_splicing,_via_spliceosome" "RNA_splicing_factor_activity,_transesterification_mechanism" U4/U6_x_U5_tri-snRNP_complex None None 4 1405847 1404438 YDR473C S000002881 "ORF,_Verified" "Splicing_factor,_component_of_the_U4/U6-U5_snRNP_complex" YDR475C JIP4 YDR474C biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1410087 1407457 YDR474C S000002883 "ORF,_Verified" "Protein_of_unknown_function;_previously_annotated_as_two_separate_ORFs,_YDR474C_and_YDR475C,_which_were_merged_as_a_result_of_corrections_to_the_systematic_reference_sequence" YDR477W SNF1 PAS14|HAF3|GLC2|CCR1|CAT1 protein_amino_acid_phosphorylation* AMP-activated_protein_kinase_activity cytoplasm* None None 4 1412366 1414267 YDR477W S000002885 "ORF,_Verified" "AMP-activated_serine/threonine_protein_kinase_found_in_a_complex_containing_Snf4p_and_members_of_the_Sip1p/Sip2p/Gal83p_family;_required_for_transcription_of_glucose-repressed_genes,_thermotolerance,_sporulation,_and_peroxisome_biogenesis" YDR481C PHO8 phoH protein_amino_acid_dephosphorylation* alkaline_phosphatase_activity vacuolar_membrane_(sensu_Fungi) G1 None 4 1420243 1418543 YDR481C S000002889 "ORF,_Verified" "Repressible_alkaline_phosphatase,_a_glycoprotein_localized_to_the_vacuole;_regulated_by_levels_of_inorganic_phosphate_and_by_a_system_consisting_of_Pho4p,_Pho9p,_Pho80p,_Pho81p_and_Pho85p;_dephosphorylates_phosphotyrosyl_peptides" YDR482C CWC21 None biological_process_unknown molecular_function_unknown spliceosome_complex None None 4 1420831 1420424 YDR482C S000002890 "ORF,_Verified" "Component_of_a_complex_containing_Cef1p,_putatively_involved_in_pre-mRNA_splicing;_may_bind_RNA;_has_similarity_to_S._pombe_Cwf21p" YDR483W KRE2 MNT1 protein_amino_acid_O-linked_glycosylation* "alpha-1,2-mannosyltransferase_activity" Golgi_apparatus None None 4 1421150 1422478 YDR483W S000002891 "ORF,_Verified" "Alpha1,2-mannosyltransferase_of_the_Golgi_involved_in_protein_mannosylation" YDR485C VPS72 SWC2 protein_targeting_to_vacuole* molecular_function_unknown cytoplasm* None None 4 1427200 1424813 YDR485C S000002893 "ORF,_Verified" "Htz1p-binding_component_of_the_SWR1_complex,_which_exchanges_histone_variant_H2AZ_(Htz1p)_for_chromatin-bound_histone_H2A;_required_for_vacuolar_protein_sorting" YDR487C RIB3 None aerobic_respiration* "3,4-dihydroxy-2-butanone-4-phosphate_synthase_activity" cytosol* None None 4 1428973 1428347 YDR487C S000002895 "ORF,_Verified" "3,4-dihydroxy-2-butanone-4-phosphate_synthase_(DHBP_synthase),_required_for_riboflavin_biosynthesis_from_ribulose-5-phosphate,_also_has_an_unrelated_function_in_mitochondrial_respiration" YDR489W SLD5 CDC105 DNA-dependent_DNA_replication molecular_function_unknown GINS_complex None None 4 1431005 1431889 YDR489W S000002897 "ORF,_Verified" "Subunit_of_the_GINS_complex_(Sld5p,_Psf1p,_Psf2p,_Psf3p),_which_is_localized_to_DNA_replication_origins_and_implicated_in_assembly_of_the_DNA_replication_machinery" YDR495C VPS3 VPT17|VPL3|PEP6 protein_targeting_to_vacuole* molecular_function_unknown cytoplasm None None 4 1441143 1438108 YDR495C S000002903 "ORF,_Verified" "Component_of_CORVET_tethering_complex;_cytoplasmic_protein_required_for_the_sorting_and_processing_of_soluble_vacuolar_proteins,_acidification_of_the_vacuolar_lumen,_and_assembly_of_the_vacuolar_H+-ATPase" YDR497C ITR1 None myo-inositol_transport myo-inositol_transporter_activity plasma_membrane* None None 4 1445460 1443706 YDR497C S000002905 "ORF,_Verified" "Myo-inositol_transporter_with_strong_similarity_to_the_minor_myo-inositol_transporter_Itr2p,_member_of_the_sugar_transporter_superfamily;_expression_is_repressed_by_inositol_and_choline_via_Opi1p_and_derepressed_via_Ino2p_and_Ino4p" YDR501W PLM2 None G1/S-specific_transcription_in_mitotic_cell_cycle transcription_factor_activity nucleus G1 None 4 1451346 1452911 YDR501W S000002909 "ORF,_Verified" Protein_required_for_partitioning_of_the_2-micron_plasmid YDR502C SAM2 ETH2 methionine_metabolism methionine_adenosyltransferase_activity cellular_component_unknown None None 4 1454457 1453303 YDR502C S000002910 "ORF,_Verified" "S-adenosylmethionine_synthetase,_catalyzes_transfer_of_the_adenosyl_group_of_ATP_to_the_sulfur_atom_of_methionine;_one_of_two_differentially_regulated_isozymes_(Sam1p_and_Sam2p)" YDR504C SPG3 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1456687 1456304 YDR504C S000002912 "ORF,_Verified" Protein_required_for_survival_at_high_temperature_during_stationary_phase;_not_required_for_growth_on_nonfermentable_carbon_sources YDR505C PSP1 GIN5 biological_process_unknown molecular_function_unknown cytoplasm* None None 4 1459213 1456688 YDR505C S000002913 "ORF,_Verified" Asn_and_gln_rich_protein_of_unknown_function;_high-copy_suppressor_of_POL1_(DNA_polymerase_alpha)_and_partial_suppressor_of_CDC2_(polymerase_delta)_and_CDC6_(pre-RC_loading_factor)_mutations;_overexpression_results_in_growth_inhibition YDR507C GIN4 ERC47 protein_amino_acid_phosphorylation* protein_kinase_activity bud_neck G1 None 4 1465779 1462351 YDR507C S000002915 "ORF,_Verified" "Protein_kinase_involved_in_bud_growth_and_assembly_of_the_septin_ring,_proposed_to_have_kinase-dependent_and_kinase-independent_activities;_undergoes_autophosphorylation;_similar_to_Kcc4p_and_Hsl1p" YDR508C GNP1 None amino_acid_transport amino_acid_transporter_activity* mitochondrion* None None 4 1468437 1466446 YDR508C S000002916 "ORF,_Verified" "High-affinity_glutamine_permease,_also_transports_Leu,_Ser,_Thr,_Cys,_Met_and_Asn;_expression_is_fully_dependent_on_Grr1p_and_modulated_by_the_Ssy1p-Ptr3p-Ssy5p_(SPS)_sensor_of_extracellular_amino_acids" YDR510W SMT3 None protein_sumoylation protein_tag nucleus* None None 4 1469393 1469698 YDR510W S000002918 "ORF,_Verified" "Ubiquitin-like_protein_of_the_SUMO_family,_conjugated_to_lysine_residues_of_target_proteins;_regulates_chromatid_cohesion,_chromosome_segregation,_APC-mediated_proteolysis,_DNA_replication_and_septin_ring_dynamics" YDR511W ACN9 None gluconeogenesis* molecular_function_unknown mitochondrial_intermembrane_space None None 4 1470010 1470411 YDR511W S000002919 "ORF,_Verified" "Protein_of_the_mitochondrial_intermembrane_space,_required_for_acetate_utilization_and_gluconeogenesis;_has_orthologs_in_higher_eukaryotes" YDR512C EMI1 None sporulation_(sensu_Fungi) molecular_function_unknown cellular_component_unknown None None 4 1471056 1470493 YDR512C S000002920 "ORF,_Verified" "Non-essential_protein_of_unknown_function_required_for_transcriptional_induction_of_the_early_meiotic-specific_transcription_factor_IME1,_also_required_for_sporulation" YDR513W GRX2 TTR1 response_to_oxidative_stress* thiol-disulfide_exchange_intermediate_activity* mitochondrion* None None 4 1471010 1471441 YDR513W S000002921 "ORF,_Verified" "Cytoplasmic_glutaredoxin,_thioltransferase,_glutathione-dependent_disulfide_oxidoreductase_involved_in_maintaining_redox_state_of_target_proteins,_also_exhibits_glutathione_peroxidase_activity,_expression_induced_in_response_to_stress" YDR519W FPR2 FKB2 biological_process_unknown peptidyl-prolyl_cis-trans_isomerase_activity endoplasmic_reticulum_membrane None None 4 1480418 1480825 YDR519W S000002927 "ORF,_Verified" "Membrane-bound_peptidyl-prolyl_cis-trans_isomerase_(PPIase),_binds_to_the_drugs_FK506_and_rapamycin;_expression_pattern_suggests_possible_involvement_in_ER_protein_trafficking" YDR525W-A SNA2 None biological_process_unknown molecular_function_unknown cytoplasm* None None 4 1490589 1490828 YDR525W-A S000007236 "ORF,_Verified" "Protein_of_unknown_function,_has_similarity_to_Pmp3p,_which_is_involved_in_cation_transport;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern" YDR529C QCR7 UCR7|CRO1|COR4 aerobic_respiration* ubiquinol-cytochrome-c_reductase_activity respiratory_chain_complex_III_(sensu_Eukaryota) None None 4 1496541 1496158 YDR529C S000002937 "ORF,_Verified" "Subunit_7_of_the_ubiquinol_cytochrome-c_reductase_complex,_which_is_a_component_of_the_mitochondrial_inner_membrane_electron_transport_chain;_oriented_facing_the_mitochondrial_matrix;_N-terminus_appears_to_play_a_role_in_complex_assembly" YDR530C APA2 None nucleotide_metabolism bis(5'-nucleosyl)-tetraphosphatase_activity* cytoplasm* None None 4 1497761 1496784 YDR530C S000002938 "ORF,_Verified" "Diadenosine_5',5''-P1,P4-tetraphosphate_phosphorylase_II_(AP4A_phosphorylase),_involved_in_catabolism_of_bis(5'-nucleosidyl)_tetraphosphates;_has_similarity_to_Apa1p" YDR532C None KRE28 biological_process_unknown molecular_function_unknown spindle_pole_body None None 4 1500546 1499389 YDR532C S000002940 "ORF,_Uncharacterized" Protein_of_unknown_function_that_localizes_to_the_nuclear_side_of_the_spindle_pole_body_and_along_short_spindles;_deletion_mutants_have_short_telomeres;_forms_a_complex_with_Spc105p YDR533C HSP31 None biological_process_unknown unfolded_protein_binding* soluble_fraction None Up 4 1502153 1501440 YDR533C S000002941 "ORF,_Verified" "Possible_chaperone_and_cysteine_protease_with_similarity_to_E._coli_Hsp31;_member_of_the_DJ-1/ThiJ/PfpI_superfamily,_which_includes_human_DJ-1_involved_in_Parkinson's_disease;_exists_as_a_dimer_and_contains_a_putative_metal-binding_site" YDR536W STL1 None transport* transporter_activity plasma_membrane* None None 4 1507997 1509706 YDR536W S000002944 "ORF,_Verified" "Glycerol_proton_symporter_of_the_plasma_membrane,_subject_to_glucose-induced_inactivation,_strongly_but_transiently_induced_when_cells_are_subjected_to_osmotic_shock" YDR541C None None biological_process_unknown dihydrokaempferol_4-reductase_activity cellular_component_unknown None None 4 1520683 1519649 YDR541C S000002949 "ORF,_Uncharacterized" Putative_dihydrokaempferol_4-reductase YDR542W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 4 1523235 1523597 YDR542W S000002950 "ORF,_Uncharacterized" Hypothetical_protein YEL001C IRC22 None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 5 150977 150300 YEL001C S000000727 "ORF,_Verified" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_localizes_to_the_ER;_YEL001C_is_non-essential;_null_mutant_displays_increased_levels_of_spontaneous_Rad52p_foci YEL002C WBP1 None protein_amino_acid_N-linked_glycosylation* dolichyl-diphosphooligosaccharide-protein_glycotransferase_activity endoplasmic_reticulum* None None 5 150013 148721 YEL002C S000000728 "ORF,_Verified" Beta_subunit_of_the_oligosaccharyl_transferase_(OST)_glycoprotein_complex;_required_for_N-linked_glycosylation_of_proteins_in_the_endoplasmic_reticulum YEL004W YEA4 None cell_wall_chitin_biosynthesis* UDP-N-acetylglucosamine_transporter_activity endoplasmic_reticulum None None 5 146950 147978 YEL004W S000000730 "ORF,_Verified" Uridine_diphosphate-N-acetylglucosamine_(UDP-GlcNAc)_transporter_required_for_cell_wall_chitin_synthesis;_localized_to_the_ER YEL006W YEA6 NDT2 transport* transporter_activity mitochondrion* None None 5 144326 145333 YEL006W S000000732 "ORF,_Verified" "Putative_mitochondrial_NAD+_transporter,_member_of_the_mitochondrial_carrier_subfamily_(see_also_YIA6);_has_putative_human_ortholog" YEL007W None TOS9 biological_process_unknown molecular_function_unknown cytoplasm* None None 5 141891 143891 YEL007W S000000733 "ORF,_Uncharacterized" Putative_protein_with_sequence_similarity_to_S._pombe_gti1+_(gluconate_transport_inducer_1) YEL009C GCN4 ARG9|AAS3 regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus None None 5 139763 138918 YEL009C S000000735 "ORF,_Verified" Basic_leucine_zipper_(bZIP)_transcriptional_activator_of_amino_acid_biosynthetic_genes_in_response_to_amino_acid_starvation;_expression_is_tightly_regulated_at_both_the_transcriptional_and_translational_levels YEL011W GLC3 GHA1 glycogen_biosynthesis "1,4-alpha-glucan_branching_enzyme_activity" cytoplasm None None 5 133120 135234 YEL011W S000000737 "ORF,_Verified" "Glycogen_branching_enzyme,_involved_in_glycogen_accumulation;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern" YEL012W UBC8 GID3 protein_monoubiquitination* ubiquitin_conjugating_enzyme_activity cytoplasm None None 5 131772 132551 YEL012W S000000738 "ORF,_Verified" "Ubiquitin-conjugating_enzyme_that_negatively_regulates_gluconeogenesis_by_mediating_the_glucose-induced_ubiquitination_of_fructose-1,6-bisphosphatase_(FBPase);_cytoplasmic_enzyme_that_catalyzes_the_ubiquitination_of_histones_in_vitro" YEL015W EDC3 LSM16|DCP3 deadenylylation-independent_decapping molecular_function_unknown cytoplasmic_mRNA_processing_body None Up 5 126629 128284 YEL015W S000000741 "ORF,_Verified" "Non-essential_conserved_protein_of_unknown_function,_plays_a_role_in_mRNA_decapping_by_specifically_affecting_the_function_of_the_decapping_enzyme_Dcp1p;_localizes_to_cytoplasmic_mRNA_processing_bodies" YEL016C NPP2 None phosphate_metabolism nucleoside-triphosphatase_activity* cellular_component_unknown None None 5 126218 124737 YEL016C S000000742 "ORF,_Verified" Nucleotide_pyrophosphatase/phosphodiesterase_family_member;_mediates_extracellular_nucleotide_phosphate_hydrolysis_along_with_Npp1p_and_Pho5p;_activity_and_expression_enhanced_during_conditions_of_phosphate_starvation YEL017C-A PMP2 None cation_transport molecular_function_unknown membrane None None 5 122929 122798 YEL017C-A S000002103 "ORF,_Verified" Proteolipid_associated_with_plasma_membrane_H(+)-ATPase_(Pma1p);_regulates_plasma_membrane_H(+)-ATPase_activity;_nearly_identical_to_PMP1 YEL017W GTT3 None glutathione_metabolism molecular_function_unknown cellular_component_unknown S/G2 None 5 123657 124670 YEL017W S000000743 "ORF,_Verified" "Protein_of_unknown_function_with_a_possible_role_in_glutathione_metabolism,_as_suggested_by_computational_analysis_of_large-scale_protein-protein_interaction_data;_GFP-fusion_protein_localizes_to_the_nuclear_periphery" YEL018W EAF5 None biological_process_unknown molecular_function_unknown nucleus* None None 5 121471 122310 YEL018W S000000744 "ORF,_Verified" "Esa1p-associated_factor,_non-essential_subunit_of_the_NuA4_acetyltransferase_complex" YEL019C MMS21 PSO10|NSE2 DNA_repair SUMO_ligase_activity cytoplasm* None None 5 121301 120498 YEL019C S000000745 "ORF,_Verified" SUMO_ligase_involved_in_chromosomal_organization_and_DNA_repair;_essential_subunit_of_the_Mms21-Smc5-Smc6_complex;_mutants_are_sensitive_to_methyl_methanesulfonate_and_show_increased_spontaneous_mutation_and_mitotic_recombination YEL020C None None biological_process_unknown molecular_function_unknown cytoplasm None Up 5 120299 118617 YEL020C S000000746 "ORF,_Uncharacterized" Hypothetical_protein_with_low_sequence_identity_to_Pdc1p YEL020W-A TIM9 None protein_import_into_mitochondrial_inner_membrane unfolded_protein_binding* mitochondrial_intermembrane_space* None None 5 117211 117474 YEL020W-A S000007256 "ORF,_Verified" "Mitochondrial_intermembrane_space_protein,_forms_a_complex_with_Mrs11p/Tim10p_that_mediates_import_and_insertion_of_a_subset_of_polytopic_inner_membrane_proteins;_may_prevent_aggregation_of_incoming_proteins_in_a_chaperone-like_manner" YEL021W URA3 None de_novo'_pyrimidine_base_biosynthesis* orotidine-5'-phosphate_decarboxylase_activity cytosol None None 5 116167 116970 YEL021W S000000747 "ORF,_Verified" "Orotidine-5'-phosphate_(OMP)_decarboxylase,_catalyzes_the_sixth_enzymatic_step_in_the_de_novo_biosynthesis_of_pyrimidines,_converting_OMP_into_uridine_monophosphate_(UMP);_converts_5-FOA_into_5-fluorouracil,_a_toxic_compound" YEL025C None SRI1 biological_process_unknown molecular_function_unknown cytoplasm* G2/M None 5 106147 102581 YEL025C S000000751 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_both_the_cytoplasm_and_the_nucleus YEL026W SNU13 None "nuclear_mRNA_splicing,_via_spliceosome*" RNA_binding* nucleolus* None Down 5 101943 102323 YEL026W S000000752 "ORF,_Verified" "RNA_binding_protein,_part_of_U3_snoRNP_involved_in_rRNA_processing,_part_of_U4/U6-U5_tri-snRNP_involved_in_mRNA_splicing,_similar_to_human_15.5K_protein" YEL031W SPF1 PER9|PIO1|COD1 protein_amino_acid_glycosylation* "ATPase_activity,_coupled_to_transmembrane_movement_of_ions,_phosphorylative_mechanism" mitochondrion* None None 5 90258 93905 YEL031W S000000757 "ORF,_Verified" "P-type_ATPase,_ion_transporter_of_the_ER_membrane_involved_in_ER_function_and_Ca2+_homeostasis;_required_for_regulating_Hmg2p_degradation;_confers_sensitivity_to_a_killer_toxin_(SMKT)_produced_by_Pichia_farinosa_KK1" YEL034W HYP2 eIF5A|TIF51A translational_initiation protein_binding* cytoplasm* None None 5 85676 86149 YEL034W S000000760 "ORF,_Verified" "Translation_initiation_factor_eIF-5A,_promotes_formation_of_the_first_peptide_bond;_similar_to_and_functionally_redundant_with_Anb1p;_possible_role_in_translation_elongation;_undergoes_an_essential_hypusination_modification" YEL035C UTR5 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 85545 85045 YEL035C S000000761 "ORF,_Uncharacterized" Protein_of_unknown_function;_transcription_may_be_regulated_by_Gcr1p YEL036C ANP1 MNN8|GEM3 protein_amino_acid_N-linked_glycosylation mannosyltransferase_activity* "alpha-1,6-mannosyltransferase_complex*" None None 5 84552 83050 YEL036C S000000762 "ORF,_Verified" "Subunit_of_the_alpha-1,6_mannosyltransferase_complex;_type_II_membrane_protein;_has_a_role_in_retention_of_glycosyltransferases_in_the_Golgi;_involved_in_osmotic_sensitivity_and_resistance_to_aminonitrophenyl_propanediol" YEL038W UTR4 None biological_process_unknown molecular_function_unknown cytoplasm* None None 5 80462 81145 YEL038W S000000764 "ORF,_Verified" "Protein_of_unknown_function_with_sequence_similarity_to_2,3-diketo-5-methylthiopentyl-1-phosphate_enolase-phosphatases,_found_in_both_the_cytoplasm_and_nucleus" YEL039C CYC7 None electron_transport electron_carrier_activity mitochondrial_intermembrane_space None None 5 79977 79636 YEL039C S000000765 "ORF,_Verified" "Cytochrome_c_isoform_2,_expressed_under_hypoxic_conditions;_electron_carrier_of_the_mitochondrial_intermembrane_space_that_transfers_electrons_from_ubiquinone-cytochrome_c_oxidoreductase_to_cytochrome_c_oxidase_during_cellular_respiration" YEL040W UTR2 CRH2 cell_wall_organization_and_biogenesis molecular_function_unknown cell_wall_(sensu_Fungi)* M/G1 None 5 78053 79456 YEL040W S000000766 "ORF,_Verified" Cell_wall_protein_that_functions_in_the_transfer_of_chitin_to_beta(1-6)glucan;_putative_chitin_transglycosidase;_glycosylphosphatidylinositol_(GPI)-anchored_protein_localized_to_the_bud_neck;_has_a_role_in_cell_wall_maintenance YEL041W YEF1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 75944 77431 YEL041W S000000767 "ORF,_Verified" ATP-NADH_kinase;_phosphorylates_both_NAD_and_NADH;_homooctameric_structure_consisting_of_60-kDa_subunits;_sequence_similarity_to_Utr1p_and_Pos5p;_overexpression_complements_certain_pos5_phenotypes YEL042W GDA1 None protein_amino_acid_glycosylation guanosine-diphosphatase_activity* Golgi_apparatus S None 5 73771 75327 YEL042W S000000768 "ORF,_Verified" "Guanosine_diphosphatase_located_in_the_Golgi,_involved_in_the_transport_of_GDP-mannose_into_the_Golgi_lumen_by_converting_GDP_to_GMP_after_mannose_is_transferred_its_substrate" YEL043W None None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 5 70478 73348 YEL043W S000000769 "ORF,_Verified" "Predicted_cytoskeleton_protein_involved_in_intracellular_signalling_based_on_quantitative_analysis_of_protein-protein_interaction_maps;_may_interact_with_ribosomes,_based_on_co-purification_studies;_contains_fibronectin_type_III_domain_fold" YEL044W IES6 None metabolism molecular_function_unknown nucleus None None 5 69757 70257 YEL044W S000000770 "ORF,_Verified" Protein_that_associates_with_the_INO80_chromatin_remodeling_complex_under_low-salt_conditions YEL046C GLY1 None threonine_catabolism* threonine_aldolase_activity cytosol None None 5 68792 67629 YEL046C S000000772 "ORF,_Verified" "Threonine_aldolase,_catalyzes_the_cleavage_of_L-allo-threonine_and_L-threonine_to_glycine;_involved_in_glycine_biosynthesis" YEL052W AFG1 None biological_process_unknown ATPase_activity mitochondrion None None 5 56571 58100 YEL052W S000000778 "ORF,_Verified" Conserved_protein_that_may_act_as_a_chaperone_in_the_degradation_of_misfolded_or_unassembled_cytochrome_c_oxidase_subunits;_localized_to_matrix_face_of_the_mitochondrial_inner_membrane;_member_of_the_AAA_family_but_lacks_a_protease_domain YEL053C MAK10 None N-terminal_protein_amino_acid_acetylation amino-acid_N-acetyltransferase_activity cytoplasm None None 5 56102 53901 YEL053C S000000779 "ORF,_Verified" "Non-catalytic_subunit_of_N-terminal_acetyltransferase_of_the_NatC_type,_required_for_replication_of_dsRNA_virus;_expression_is_glucose-repressible" YEL054C RPL12A None protein_biosynthesis* structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None Down 5 53218 52721 YEL054C S000000780 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl12Bp;_rpl12a_rpl12b_double_mutant_exhibits_slow_growth_and_slow_translation;_has_similarity_to_E._coli_L11_and_rat_L12_ribosomal_proteins" YEL055C POL5 None rRNA_transcription DNA-directed_DNA_polymerase_activity nucleolus None None 5 51539 48471 YEL055C S000000781 "ORF,_Verified" "DNA_Polymerase_phi;_has_sequence_similarity_to_the_human_MybBP1A_and_weak_sequence_similarity_to_B-type_DNA_polymerases,_not_required_for_chromosomal_DNA_replication;_required_for_the_synthesis_of_rRNA" YEL057C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 45721 45020 YEL057C S000000783 "ORF,_Uncharacterized" Protein_of_unknown_function_involved_in_telomere_maintenance;_target_of_UME6_regulation YEL058W PCM1 AGM1 N-acetylglucosamine_biosynthesis phosphoacetylglucosamine_mutase_activity cytoplasm* None None 5 43252 44925 YEL058W S000000784 "ORF,_Verified" "Essential_N-acetylglucosamine-phosphate_mutase;_converts_GlcNAc-6-P_to_GlcNAc-1-P,_which_is_a_precursor_for_the_biosynthesis_of_chitin_and_for_the_formation_of_N-glycosylated_mannoproteins_and_glycosylphosphatidylinositol_anchors" YEL059C-A SOM1 None proteolysis molecular_function_unknown mitochondrial_inner_membrane* None None 5 42624 42400 YEL059C-A S000002954 "ORF,_Verified" "Subunit_of_the_mitochondrial_inner_membrane_peptidase,_which_is_required_for_maturation_of_mitochondrial_proteins_of_the_intermembrane_space;_Som1p_facilitates_cleavage_of_a_subset_of_substrates" YEL060C PRB1 CVT1 sporulation* serine-type_endopeptidase_activity vacuole_(sensu_Fungi)* S None 5 41953 40046 YEL060C S000000786 "ORF,_Verified" "Vacuolar_proteinase_B_(yscB),_a_serine_protease_of_the_subtilisin_family;_involved_in_protein_degradation_in_the_vacuole_and_required_for_full_protein_degradation_during_sporulation" YEL062W NPR2 None urea_transport* channel_regulator_activity cellular_component_unknown None None 5 34407 36254 YEL062W S000000788 "ORF,_Verified" Protein_with_a_possible_role_in_regulating_expression_of_nitrogen_permeases;_transcription_is_induced_in_response_to_proline_and_urea;_contains_two_PEST_sequences;_null_mutant_is_resistant_to_cisplatin_and_doxorubicin YEL065W SIT1 ARN3 iron_ion_homeostasis* siderophore-iron_(ferrioxamine)_uptake_transporter_activity endosome* G2/M None 5 27657 29543 YEL065W S000000791 "ORF,_Verified" "Ferrioxamine_B_transporter,_member_of_the_ARN_family_of_transporters_that_specifically_recognize_siderophore-iron_chelates;_transcription_is_induced_during_iron_deprivation_and_diauxic_shift;_potentially_phosphorylated_by_Cdc28p" YEL066W HPA3 None histone_acetylation histone_acetyltransferase_activity cytoplasm* None None 5 26667 27206 YEL066W S000000792 "ORF,_Verified" "D-Amino_acid_N-acetyltransferase,_catalyzes_N-acetylation_of_D-amino_acids_through_ordered_bi-bi_mechanism_in_which_acetyl-CoA_is_first_substrate_bound_and_CoA_is_last_product_liberated;_similar_to_Hpa2p,_acetylates_histones_weakly_in_vitro" YEL076C-A None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 5 5114 4185 YEL076C-A S000002955 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YER001W MNN1 None protein_amino_acid_O-linked_glycosylation* "alpha-1,3-mannosyltransferase_activity" Golgi_apparatus G1 None 5 153519 155807 YER001W S000000803 "ORF,_Verified" "Alpha-1,3-mannosyltransferase,_integral_membrane_glycoprotein_of_the_Golgi_complex,_required_for_addition_of_alpha1,3-mannose_linkages_to_N-linked_and_O-linked_oligosaccharides,_one_of_five_S._cerevisiae_proteins_of_the_MNN1_family" YER002W NOP16 None ribosomal_large_subunit_biogenesis molecular_function_unknown nucleus* None None 5 156802 157497 YER002W S000000804 "ORF,_Verified" "Constituent_of_66S_pre-ribosomal_particles,_involved_in_60S_ribosomal_subunit_biogenesis" YER003C PMI40 PMI protein_amino_acid_glycosylation* mannose-6-phosphate_isomerase_activity cytoplasm* S None 5 159117 157735 YER003C S000000805 "ORF,_Verified" "Mannose-6-phosphate_isomerase,_catalyzes_the_interconversion_of_fructose-6-P_and_mannose-6-P;_required_for_early_steps_in_protein_mannosylation" YER004W FMP52 None biological_process_unknown molecular_function_unknown mitochondrion* None None 5 159579 160274 YER004W S000000806 "ORF,_Verified" "Protein_of_unknown_function,_localized_to_the_mitochondrial_outer_membrane;_induced_by_treatment_with_8-methoxypsoralen_and_UVA_irradiation" YER005W YND1 YEJ5 protein_amino_acid_glycosylation nucleoside-diphosphatase_activity Golgi_apparatus* None None 5 160549 162441 YER005W S000000807 "ORF,_Verified" "Apyrase_with_wide_substrate_specificity,_involved_in_preventing_the_inhibition_of_glycosylation_by_hydrolyzing_nucleoside_tri-_and_diphosphates_which_are_inhibitors_of_glycotransferases;_partially_redundant_with_Gda1p" YER006W NUG1 None rRNA_processing GTPase_activity nucleus* None None 5 162722 164284 YER006W S000000808 "ORF,_Verified" "GTPase_that_associates_with_nuclear_60S_pre-ribosomes,_required_for_export_of_60S_ribosomal_subunits_from_the_nucleus" YER007C-A TMA20 RBF20 biological_process_unknown RNA_binding cytoplasm None None 5 166884 166236 YER007C-A S000002957 "ORF,_Verified" Protein_of_unknown_function_that_associates_with_ribosomes_and_has_a_putative_RNA_binding_domain;_interacts_with_Tma22p;_null_mutant_exhibits_translation_defects;_has_homology_to_human_oncogene_MCT-1 YER008C SEC3 PSL1 cytokinesis* protein_binding bud_neck* None None 5 171817 167807 YER008C S000000810 "ORF,_Verified" "Non-essential_subunit_of_the_exocyst_complex_(Sec3p,_Sec5p,_Sec6p,_Sec8p,_Sec10p,_Sec15p,_Exo70p,_Exo84p)_which_mediates_targeting_of_post-Golgi_vesicles_to_sites_of_active_exocytosis;_Sec3p_specifically_is_a_spatial_landmark_for_secretion" YER009W NTF2 None protein_import_into_nucleus* Ran_GTPase_binding nuclear_envelope None None 5 172114 172491 YER009W S000000811 "ORF,_Verified" "Nuclear_envelope_protein,_interacts_with_GDP-bound_Gsp1p_and_with_proteins_of_the_nuclear_pore_to_transport_Gsp1p_into_the_nucleus_where_it_is_an_essential_player_in_nucleocytoplasmic_transport" YER010C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 173337 172633 YER010C S000000812 "ORF,_Verified" "Protein_of_unknown_function,_forms_a_ring-shaped_homotrimer;_has_similarity_to_members_of_the_prokaryotic_rraA_family;_possibly_involved_in_a_phosphotransfer_reaction" YER011W TIR1 SRP1 response_to_stress structural_constituent_of_cell_wall cell_wall_(sensu_Fungi) S/G2 None 5 175247 176011 YER011W S000000813 "ORF,_Verified" Cell_wall_mannoprotein_of_the_Srp1p/Tip1p_family_of_serine-alanine-rich_proteins;_expression_is_downregulated_at_acidic_pH_and_induced_by_cold_shock_and_anaerobiosis;_abundance_is_increased_in_cells_cultured_without_shaking YER012W PRE1 None response_to_stress* endopeptidase_activity nucleus* None None 5 177834 178430 YER012W S000000814 "ORF,_Verified" Beta_4_subunit_of_the_20S_proteasome;_localizes_to_the_nucleus_throughout_the_cell_cycle YER016W BIM1 EB1|YEB1 microtubule_nucleation* structural_constituent_of_cytoskeleton spindle_pole_body* G1 None 5 188276 189310 YER016W S000000818 "ORF,_Verified" Microtubule-binding_protein_that_together_with_Kar9p_makes_up_the_cortical_microtubule_capture_site_and_delays_the_exit_from_mitosis_when_the_spindle_is_oriented_abnormally YER017C AFG3 YTA10 protein_complex_assembly* ATPase_activity* mitochondrial_inner_membrane* None None 5 191787 189502 YER017C S000000819 "ORF,_Verified" "Component,_with_Yta12p,_of_the_mitochondrial_inner_membrane_m-AAA_protease_that_mediates_degradation_of_misfolded_or_unassembled_proteins_and_is_also_required_for_correct_assembly_of_mitochondrial_enzyme_complexes" YER018C SPC25 None chromosome_segregation* structural_constituent_of_cytoskeleton condensed_nuclear_chromosome_kinetochore* S/G2 None 5 192623 191958 YER018C S000000820 "ORF,_Verified" "Component_of_the_evolutionarily_conserved_kinetochore-associated_Ndc80_complex_(Ndc80p-Nuf2p-Spc24p-Spc25p);_involved_in_chromosome_segregation,_spindle_checkpoint_activity_and_kinetochore_clustering" YER019C-A SBH2 SEB2 cotranslational_protein_targeting_to_membrane protein_transporter_activity* endoplasmic_reticulum* None None 5 194538 194272 YER019C-A S000002127 "ORF,_Verified" "Ssh1p-Sss1p-Sbh2p_complex_component,_involved_in_protein_translocation_into_the_endoplasmic_reticulum;_homologous_to_Sbh1p" YER019W ISC1 None response_to_salt_stress* phospholipase_C_activity mitochondrion* G1 None 5 192796 194229 YER019W S000000821 "ORF,_Verified" "Mitochondrial_membrane_localized_inositol_phosphosphingolipid_phospholipase_C,_hydrolyzes_complex_sphingolipids_to_produce_ceramide;_activated_by_phosphatidylserine,_cardiolipin,_and_phosphatidylglycerol;_mediates_Na+_and_Li+_halotolerance" YER021W RPN3 SUN2 ubiquitin-dependent_protein_catabolism molecular_function_unknown "proteasome_regulatory_particle,_lid_subcomplex_(sensu_Eukaryota)" None None 5 196947 198518 YER021W S000000823 "ORF,_Verified" "Essential,_non-ATPase_regulatory_subunit_of_the_26S_proteasome_lid,_similar_to_the_p58_subunit_of_the_human_26S_proteasome;_temperature-sensitive_alleles_cause_metaphase_arrest,_suggesting_a_role_for_the_proteasome_in_cell_cycle_control" YER023W PRO3 ORE2 proline_biosynthesis pyrroline-5-carboxylate_reductase_activity cytoplasm None None 5 201075 201935 YER023W S000000825 "ORF,_Verified" "Delta_1-pyrroline-5-carboxylate_reductase,_catalyzes_the_last_step_in_proline_biosynthesis" YER026C CHO1 PSS1 phosphatidylserine_biosynthesis CDP-diacylglycerol-serine_O-phosphatidyltransferase_activity endoplasmic_reticulum None None 5 208473 207643 YER026C S000000828 "ORF,_Verified" "Phosphatidylserine_synthase,_functions_in_phospholipid_biosynthesis;_catalyzes_the_reaction_CDP-diaclyglycerol_+_L-serine_=_CMP_+_L-1-phosphatidylserine,_transcriptionally_repressed_by_myo-inositol_and_choline" YER027C GAL83 SPM1 protein_amino_acid_phosphorylation* AMP-activated_protein_kinase_activity nucleus None None 5 210231 208978 YER027C S000000829 "ORF,_Verified" "One_of_three_possible_beta-subunits_of_the_Snf1_kinase_complex,_allows_nuclear_localization_of_the_Snf1_kinase_complex_in_the_presence_of_a_nonfermentable_carbon_source;_contains_glycogen-binding_domain" YER028C MIG3 None negative_regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus None None 5 211875 210691 YER028C S000000830 "ORF,_Verified" "Probable_transcriptional_repressor_involved_in_response_to_toxic_agents_such_as_hydroxyurea_that_inhibit_ribonucleotide_reductase;_phosphorylation_by_Snf1p_or_the_Mec1p_pathway_inactivates_Mig3p,_allowing_induction_of_damage_response_genes" YER029C SMB1 None "nuclear_mRNA_splicing,_via_spliceosome" "RNA_splicing_factor_activity,_transesterification_mechanism" U4/U6_x_U5_tri-snRNP_complex* None None 5 213176 212586 YER029C S000000831 "ORF,_Verified" "Core_Sm_protein_Sm_B;_part_of_heteroheptameric_complex_(with_Smd1p,_Smd2p,_Smd3p,_Sme1p,_Smx3p,_and_Smx2p)_that_is_part_of_the_spliceosomal_U1,_U2,_U4,_and_U5_snRNPs;_homolog_of_human_Sm_B_and_Sm_B'" YER030W CHZ1 None biological_process_unknown molecular_function_unknown nucleus None None 5 213436 213897 YER030W S000000832 "ORF,_Verified" Histone_chaperone_for_Htz1p/H2A-H2B_dimer;_required_for_the_stabilization_of_the_Chz1p-Htz1-H2B_complex;_has_overlapping_function_with_Nap1p;_null_mutant_displays_weak_sensitivity_to_MMS_and_benomyl;_contains_a_highly_conserved_CHZ_motif YER032W FIR1 PIP1 mRNA_polyadenylylation molecular_function_unknown bud_neck S/G2 None 5 215062 217692 YER032W S000000834 "ORF,_Verified" "Protein_involved_in_3'_mRNA_processing,_interacts_with_Ref2p;_potential_Cdc28p_substrate" YER033C ZRG8 None biological_process_unknown molecular_function_unknown cytoplasm* None None 5 221286 218056 YER033C S000000835 "ORF,_Verified" "Protein_of_unknown_function;_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_GFP-fusion_protein_is_localized_to_the_cytoplasm;_transcription_induced_under_conditions_of_zinc_deficiency" YER034W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 5 221845 222402 YER034W S000000836 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene;_expression_induced_upon_calcium_shortage YER035W EDC2 None deadenylylation-dependent_decapping RNA_binding cytoplasm* None None 5 222638 223075 YER035W S000000837 "ORF,_Verified" "RNA-binding_protein,_activates_mRNA_decapping_directly_by_binding_to_the_mRNA_substrate_and_enhancing_the_activity_of_the_decapping_proteins_Dcp1p_and_Dcp2p" YER036C ARB1 None biological_process_unknown "ATPase_activity,_coupled_to_transmembrane_movement_of_substances" cytoplasm None None 5 225198 223366 YER036C S000000838 "ORF,_Verified" "ATPase_of_the_ATP-binding_cassette_(ABC)_family_involved_in_40S_and_60S_ribosome_biogenesis,_has_similarity_to_Gcn20p;_shuttles_from_nucleus_to_cytoplasm,_physically_interacts_with_Tif6p,_Lsg1p" YER038C KRE29 None biological_process_unknown molecular_function_unknown cytoplasm* None None 5 228251 226857 YER038C S000000840 "ORF,_Verified" Essential_subunit_of_the_Mms21-Smc5-Smc6_complex;_protein_of_unknown_function;_required_for_growth_and_DNA_repair;_heterozygous_mutant_shows_haploinsufficiency_in_K1_killer_toxin_resistance YER040W GLN3 None positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_factor_activity* nucleus* None None 5 229794 231986 YER040W S000000842 "ORF,_Verified" "Transcriptional_activator_of_genes_regulated_by_nitrogen_catabolite_repression_(NCR),_localization_and_activity_regulated_by_quality_of_nitrogen_source" YER041W YEN1 None biological_process_unknown single-stranded_DNA_specific_endodeoxyribonuclease_activity nucleus None None 5 232460 234739 YER041W S000000843 "ORF,_Verified" "Protein_of_unknown_function,_has_similarity_to_endonuclease_Rth1p;_potentially_phosphorylated_by_Cdc28p" YER042W MXR1 MSRA response_to_oxidative_stress protein-methionine-S-oxide_reductase_activity cytoplasm* S/G2 None 5 234936 235490 YER042W S000000844 "ORF,_Verified" "Peptide_methionine_sulfoxide_reductase,_reverses_the_oxidation_of_methionine_residues;_involved_in_oxidative_damage_repair,_providing_resistance_to_oxidative_stress_and_regulation_of_lifespan" YER043C SAH1 None methionine_metabolism* adenosylhomocysteinase_activity cytoplasm None Down 5 237118 235769 YER043C S000000845 "ORF,_Verified" "S-adenosyl-L-homocysteine_hydrolase,_catabolizes_S-adenosyl-L-homocysteine_which_is_formed_after_donation_of_the_activated_methyl_group_of_S-adenosyl-L-methionine_(AdoMet)_to_an_acceptor" YER044C ERG28 BUD18 ergosterol_biosynthesis "protein_binding,_bridging" endoplasmic_reticulum_membrane None None 5 238015 237569 YER044C S000000846 "ORF,_Verified" "Endoplasmic_reticulum_membrane_protein,_may_facilitate_protein-protein_interactions_between_the_Erg26p_dehydrogenase_and_the_Erg27p_3-ketoreductase_and/or_tether_these_enzymes_to_the_ER,_also_interacts_with_Erg6p" YER044C-A MEI4 None sporulation_(sensu_Fungi)* molecular_function_unknown cellular_component_unknown None None 5 239773 238459 YER044C-A S000001954 "ORF,_Verified" Meiosis-specific_protein_involved_in_recombination;_required_for_chromosome_synapsis;_required_for_production_of_viable_spores YER047C SAP1 None biological_process_unknown ATPase_activity cytoplasm None None 5 246502 243809 YER047C S000000849 "ORF,_Verified" "Putative_ATPase_of_the_AAA_family,_interacts_with_the_Sin1p_transcriptional_repressor_in_the_two-hybrid_system" YER048C CAJ1 None biological_process_unknown chaperone_regulator_activity nucleus None None 5 248156 246981 YER048C S000000850 "ORF,_Verified" "Nuclear_type_II_J_heat_shock_protein_of_the_E._coli_dnaJ_family,_contains_a_leucine_zipper-like_motif,_binds_to_non-native_substrates_for_presentation_to_Ssa3p,_may_function_during_protein_translocation,_assembly_and_disassembly" YER048W-A ISD11 None biological_process_unknown molecular_function_unknown mitochondrion None None 5 250717 251001 YER048W-A S000007237 "ORF,_Verified" Protein_required_for_mitochondrial_iron-sulfur_cluster_biosynthesis YER049W TPA1 None biological_process_unknown molecular_function_unknown nucleus None None 5 251727 253661 YER049W S000000851 "ORF,_Verified" "Protein_of_unknown_function;_interacts_with_Sup45p_(eRF1),_Sup35p_(eRF3)_and_Pab1p;_has_a_role_in_translation_termination_efficiency,_mRNA_poly(A)_tail_length_and_mRNA_stability" YER050C RSM18 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 5 254386 253970 YER050C S000000852 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_small_subunit,_has_similarity_to_E._coli_S18_ribosomal_protein" YER051W JHD1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 254655 256133 YER051W S000000853 "ORF,_Verified" "JmjC_domain_family_histone_demethylase_specific_for_H3-K36,_similar_to_proteins_found_in_human,_mouse,_drosophila,_X._laevis,_C._elegans,_and_S._pombe" YER052C HOM3 SIL4|BOR1 methionine_metabolism* aspartate_kinase_activity cytoplasm None Up 5 257957 256374 YER052C S000000854 "ORF,_Verified" Aspartate_kinase_(L-aspartate_4-P-transferase);_cytoplasmic_enzyme_that_catalyzes_the_first_step_in_the_common_pathway_for_methionine_and_threonine_biosynthesis;_expression_regulated_by_Gcn4p_and_the_general_control_of_amino_acid_synthesis YER053C PIC2 None phosphate_transport inorganic_phosphate_transporter_activity mitochondrion None None 5 259638 258736 YER053C S000000855 "ORF,_Verified" "Mitochondrial_phosphate_carrier,_imports_inorganic_phosphate_into_mitochondria;_functionally_redundant_with_Mir1p_but_less_abundant_than_Mir1p_under_normal_conditions;_expression_is_induced_at_high_temperature" YER054C GIP2 None protein_amino_acid_dephosphorylation* protein_phosphatase_regulator_activity protein_phosphatase_type_1_complex None None 5 263697 262051 YER054C S000000856 "ORF,_Verified" "Putative_regulatory_subunit_of_the_protein_phosphatase_Glc7p,_involved_in_glycogen_metabolism;_contains_a_conserved_motif_(GVNK_motif)_that_is_also_found_in_Gac1p,_Pig1p,_and_Pig2p" YER055C HIS1 None histidine_biosynthesis ATP_phosphoribosyltransferase_activity intracellular None None 5 265784 264891 YER055C S000000857 "ORF,_Verified" "ATP_phosphoribosyltransferase,_a_hexameric_enzyme,_catalyzes_the_first_step_in_histidine_biosynthesis;_mutations_cause_histidine_auxotrophy_and_sensitivity_to_Cu,_Co,_and_Ni_salts;_transcription_is_regulated_by_general_amino_acid_control" YER056C FCY2 BRA7 purine_transport* cytosine-purine_permease_activity* plasma_membrane None None 5 268112 266511 YER056C S000000858 "ORF,_Verified" "Purine-cytosine_permease,_mediates_purine_(adenine,_guanine,_and_hypoxanthine)_and_cytosine_accumulation" YER056C-A RPL34A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 5 270183 269421 YER056C-A S000002135 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl34Bp_and_has_similarity_to_rat_L34_ribosomal_protein" YER058W PET117 None cytochrome_c_oxidase_complex_assembly molecular_function_unknown mitochondrial_inner_membrane None None 5 271766 272089 YER058W S000000860 "ORF,_Verified" Protein_required_for_assembly_of_cytochrome_c_oxidase YER059W PCL6 None regulation_of_glycogen_biosynthesis* cyclin-dependent_protein_kinase_regulator_activity cyclin-dependent_protein_kinase_holoenzyme_complex None None 5 272622 273884 YER059W S000000861 "ORF,_Verified" Pho85p_cyclin_of_the_Pho80p_subfamily;_forms_the_major_Glc8p_kinase_together_with_Pcl7p_and_Pho85p;_involved_in_the_control_of_glycogen_storage_by_Pho85p;_stabilized_by_Elongin_C_binding YER060W FCY21 None biological_process_unknown cytosine-purine_permease_activity integral_to_membrane None None 5 274565 276151 YER060W S000000862 "ORF,_Verified" "Putative_purine-cytosine_permease,_very_similar_to_Fcy2p_but_cannot_substitute_for_its_function" YER060W-A FCY22 None biological_process_unknown cytosine-purine_permease_activity integral_to_membrane None None 5 276570 278162 YER060W-A S000002958 "ORF,_Verified" "Putative_purine-cytosine_permease,_very_similar_to_Fcy2p_but_cannot_substitute_for_its_function" YER061C CEM1 None fatty_acid_biosynthesis fatty-acid_synthase_activity mitochondrion None None 5 279624 278296 YER061C S000000863 "ORF,_Verified" Mitochondrial_beta-keto-acyl_synthase_with_possible_role_in_fatty_acid_synthesis;_required_for_mitochondrial_respiration YER062C HOR2 GPP2 response_to_osmotic_stress* glycerol-1-phosphatase_activity cytoplasm* None None 5 280680 279928 YER062C S000000864 "ORF,_Verified" "One_of_two_redundant_DL-glycerol-3-phosphatases_(RHR2/GPP1_encodes_the_other)_involved_in_glycerol_biosynthesis;_induced_in_response_to_hyperosmotic_stress_and_oxidative_stress,_and_during_the_diauxic_transition" YER063W THO1 None "transcription,_DNA-dependent" molecular_function_unknown nucleus None None 5 281708 282364 YER063W S000000865 "ORF,_Verified" "Conserved_nuclear_RNA-binding_protein;_specifically_binds_to_transcribed_chromatin_in_a_THO-_and_RNA-dependent_manner,_genetically_interacts_with_shuttling_hnRNP_NAB2;_overproduction_suppresses_transcriptional_defect_caused_by_hpr1_mutation" YER064C None None regulation_of_transcription molecular_function_unknown nucleus None None 5 284220 282703 YER064C S000000866 "ORF,_Uncharacterized" Non-essential_nuclear_protein;_null_mutation_has_global_effects_on_transcription YER065C ICL1 None glyoxylate_cycle isocitrate_lyase_activity cellular_component_unknown None None 5 286912 285239 YER065C S000000867 "ORF,_Verified" "Isocitrate_lyase,_catalyzes_the_formation_of_succinate_and_glyoxylate_from_isocitrate,_a_key_reaction_of_the_glyoxylate_cycle;_expression_of_ICL1_is_induced_by_growth_on_ethanol_and_repressed_by_growth_on_glucose" YER067W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 5 292064 292549 YER067W S000000869 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_YER067W_is_not_an_essential_gene YER068W MOT2 SIG1|NOT4 regulation_of_transcription_from_RNA_polymerase_II_promoter* 3'-5'-exoribonuclease_activity* cytoplasm* None None 5 293048 294811 YER068W S000000870 "ORF,_Verified" "Component_of_the_CCR4-NOT_complex,_which_has_multiple_roles_in_transcription_regulation,_mRNA_degradation,_and_post-transcriptional_modifications;_with_Ubc4p,_ubiquitylates_subunits_of_the_nascent_polypeptide-associated_complex_(NAC)" YER069W "ARG5,6" None regulation_of_transcription* N-acetyl-gamma-glutamyl-phosphate_reductase_activity* mitochondrial_matrix None Up 5 295408 297999 YER069W S000000871 "ORF,_Verified" "Protein_that_is_processed_in_the_mitochondrion_to_yield_acetylglutamate_kinase_and_N-acetyl-gamma-glutamyl-phosphate_reductase,_which_catalyze_the_2nd_and_3rd_steps_in_arginine_biosynthesis;_enzymes_form_a_complex_with_Arg2p" YER070W RNR1 SDS12|RIR1|CRT7 DNA_replication ribonucleoside-diphosphate_reductase_activity cytoplasm* G1 Up 5 298948 301614 YER070W S000000872 "ORF,_Verified" "One_of_two_large_regulatory_subunits_of_ribonucleotide-diphosphate_reductase;_the_RNR_complex_catalyzes_rate-limiting_step_in_dNTP_synthesis,_regulated_by_DNA_replication_and_DNA_damage_checkpoint_pathways_via_localization_of_small_subunits" YER071C None None biological_process_unknown molecular_function_unknown cytoplasm None None 5 302325 301945 YER071C S000000873 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern YER072W VTC1 PHM4|NRF1 "vacuole_fusion,_non-autophagic" molecular_function_unknown intrinsic_to_vacuolar_membrane None None 5 302804 303193 YER072W S000000874 "ORF,_Verified" "Vacuolar_transporter_chaperon_(VTC)_involved_in_distributing_V-ATPase_and_other_membrane_proteins;_together_with_other_VTC_proteins,_forms_a_heterotetrameric_complex_that_associates_with_the_SNARE_Nyv1p_and_the_V0_sector_of_the_V-ATPase" YER073W ALD5 None electron_transport* aldehyde_dehydrogenase_activity mitochondrion None None 5 304027 305589 YER073W S000000875 "ORF,_Verified" "Mitochondrial_aldehyde_dehydrogenase,_involved_in_regulation_or_biosynthesis_of_electron_transport_chain_components_and_acetate_formation;_activated_by_K+;_utilizes_NADP+_as_the_preferred_coenzyme;_constitutively_expressed" YER074W RPS24A RPS24EA protein_biosynthesis structural_constituent_of_ribosome mitochondrion* None None 5 306319 307192 YER074W S000000876 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_identical_to_Rps24Bp_and_has_similarity_to_rat_S24_ribosomal_protein YER075C PTP3 None protein_amino_acid_dephosphorylation* protein_tyrosine_phosphatase_activity cytoplasm None None 5 311195 308409 YER075C S000000877 "ORF,_Verified" Phosphotyrosine-specific_protein_phosphatase_involved_in_the_inactivation_of_mitogen-activated_protein_kinase_(MAPK)_during_osmolarity_sensing;_dephosporylates_Hog1p_MAPK_and_regulates_its_localization;_localized_to_the_cytoplasm YER076C None None biological_process_unknown molecular_function_unknown mitochondrion* None None 5 313494 312586 YER076C S000000878 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_analysis_of_HA-tagged_protein_suggests_a_membrane_localization" YER077C None None biological_process_unknown molecular_function_unknown mitochondrion None None 5 316596 314530 YER077C S000000879 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_mitochondrion;_null_mutation_results_in_a_decrease_in_plasma_membrane_electron_transport YER079W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 5 318916 319548 YER079W S000000881 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YER080W None FMP29 biological_process_unknown molecular_function_unknown mitochondrion None None 5 319959 321842 YER080W S000000882 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_null_mutant_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation)" YER081W SER3 None serine_family_amino_acid_biosynthesis phosphoglycerate_dehydrogenase_activity cytoplasm None None 5 322682 324091 YER081W S000000883 "ORF,_Verified" "3-phosphoglycerate_dehydrogenase,_catalyzes_the_first_step_in_serine_and_glycine_biosynthesis;_isozyme_of_Ser33p" YER082C UTP7 KRE31 rRNA_processing snoRNA_binding small_nucleolar_ribonucleoprotein_complex None None 5 325932 324268 YER082C S000000884 "ORF,_Verified" "Nucleolar_protein,_component_of_the_small_subunit_(SSU)_processome_containing_the_U3_snoRNA_that_is_involved_in_processing_of_pre-18S_rRNA" YER083C GET2 RMD7|HUR2 cell_wall_organization_and_biogenesis* molecular_function_unknown endoplasmic_reticulum* None None 5 327027 326170 YER083C S000000885 "ORF,_Verified" Subunit_of_the_GET_complex;_required_for_meiotic_nuclear_division_and_for_the_retrieval_of_HDEL_proteins_from_the_Golgi_to_the_ER_in_an_ERD2_dependent_fashion;_may_be_involved_in_cell_wall_function YER085C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 328136 327615 YER085C S000000887 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YER087W None None biological_process_unknown proline-tRNA_ligase_activity cellular_component_unknown None None 5 330572 332302 YER087W S000000889 "ORF,_Uncharacterized" "Protein_with_similarity_to_tRNA_synthetases;_non-tagged_protein_is_detected_in_purified_mitochondria;_null_mutant_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation),_severe_growth_defect_in_minimal_glycerol_media" YER090W TRP2 None tryptophan_biosynthesis anthranilate_synthase_activity cytoplasm* None Up 5 337945 339468 YER090W S000000892 "ORF,_Verified" "Anthranilate_synthase,_catalyzes_the_initial_step_of_tryptophan_biosynthesis,_forms_multifunctional_hetero-oligomeric_anthranilate_synthase:indole-3-glycerol_phosphate_synthase_enzyme_complex_with_Trp3p" YER091C MET6 None methionine_biosynthesis 5-methyltetrahydropteroyltriglutamate-homocysteine_S-methyltransferase_activity cytoplasm S None 5 342163 339860 YER091C S000000893 "ORF,_Verified" "Cobalamin-independent_methionine_synthase,_involved_in_amino_acid_biosynthesis;_requires_a_minimum_of_two_glutamates_on_the_methyltetrahydrofolate_substrate,_similar_to_bacterial_metE_homologs" YER092W IES5 None biological_process_unknown molecular_function_unknown nucleus None None 5 342851 343228 YER092W S000000894 "ORF,_Verified" Protein_that_associates_with_the_INO80_chromatin_remodeling_complex_under_low-salt_conditions YER093C TSC11 AVO3 cell_wall_organization_and_biogenesis* protein_binding TORC_2_complex None None 5 347608 343316 YER093C S000000895 "ORF,_Verified" "Subunit_of_TORC2_(Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p),_a_membrane-associated_complex_that_regulates_actin_cytoskeletal_dynamics_during_polarized_growth_and_cell_wall_integrity;_involved_in_sphingolipid_metabolism;_contains_a_RasGEFN_domain" YER093C-A None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 348396 347908 YER093C-A S000002960 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YER093C-A_contains_an_intron;_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation) YER094C PUP3 SCS32 ubiquitin-dependent_protein_catabolism endopeptidase_activity "proteasome_core_complex,_beta-subunit_complex_(sensu_Eukaryota)" None None 5 349342 348725 YER094C S000000896 "ORF,_Verified" Beta_3_subunit_of_the_20S_proteasome_involved_in_ubiquitin-dependent_catabolism;_human_homolog_is_subunit_C10 YER095W RAD51 MUT5 telomerase-independent_telomere_maintenance* recombinase_activity nuclear_chromosome* G1 None 5 349976 351178 YER095W S000000897 "ORF,_Verified" "Strand_exchange_protein,_forms_a_helical_filament_with_DNA_that_searches_for_homology;_involved_in_the_recombinational_repair_of_double-strand_breaks_in_DNA_during_vegetative_growth_and_meiosis;_homolog_of_Dmc1p_and_bacterial_RecA_protein" YER096W SHC1 None sporulation_(sensu_Fungi)* enzyme_activator_activity prospore_membrane None None 5 351694 353232 YER096W S000000898 "ORF,_Verified" "Sporulation-specific_activator_of_Chs3p_(chitin_synthase_III),_required_for_the_synthesis_of_the_chitosan_layer_of_ascospores;_has_similarity_to_Skt5p,_which_activates_Chs3p_during_vegetative_growth;_transcriptionally_induced_at_alkaline_pH" YER098W UBP9 None protein_deubiquitination ubiquitin-specific_protease_activity cytoplasm None None 5 355462 357726 YER098W S000000900 "ORF,_Verified" "Ubiquitin_carboxyl-terminal_hydrolase,_ubiquitin-specific_protease_that_cleaves_ubiquitin-protein_fusions" YER099C PRS2 None histidine_biosynthesis* ribose_phosphate_diphosphokinase_activity cytoplasm None None 5 359057 358101 YER099C S000000901 "ORF,_Verified" "5-phospho-ribosyl-1(alpha)-pyrophosphate_synthetase,_synthesizes_PRPP,_which_is_required_for_nucleotide,_histidine,_and_tryptophan_biosynthesis;_one_of_five_related_enzymes,_which_are_active_as_heteromultimeric_complexes" YER100W UBC6 DOA2 ER-associated_protein_catabolism* ubiquitin_conjugating_enzyme_activity endoplasmic_reticulum_membrane None None 5 359558 360310 YER100W S000000902 "ORF,_Verified" Ubiquitin-conjugating_enzyme_involved_in_ER-associated_protein_degradation;_located_at_the_cytosolic_side_of_the_ER_membrane;_tail_region_contains_a_transmembrane_segment_at_the_C-terminus;_substrate_of_the_ubiquitin-proteasome_pathway YER101C AST2 None biological_process_unknown molecular_function_unknown cytoplasm None None 5 361790 360498 YER101C S000000903 "ORF,_Verified" "Protein_that_may_have_a_role_in_targeting_of_plasma_membrane_[H+]ATPase_(Pma1p)_to_the_plasma_membrane,_as_suggested_by_analysis_of_genetic_interactions" YER102W RPS8B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 5 363096 363698 YER102W S000000904 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_identical_to_Rps8Ap_and_has_similarity_to_rat_S8_ribosomal_protein YER103W SSA4 YG107 response_to_stress* unfolded_protein_binding cytoplasm* None None 5 364585 366513 YER103W S000000905 "ORF,_Verified" Heat_shock_protein_that_is_highly_induced_upon_stress;_plays_a_role_in_SRP-dependent_cotranslational_protein-membrane_targeting_and_translocation;_member_of_the_HSP70_family;_cytoplasmic_protein_that_concentrates_in_nuclei_upon_starvation YER104W RTT105 None negative_regulation_of_DNA_transposition molecular_function_unknown cytoplasm* None None 5 366798 367424 YER104W S000000906 "ORF,_Verified" Protein_with_a_role_in_regulation_of_Ty1_transposition YER105C NUP157 None mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 5 372009 367834 YER105C S000000907 "ORF,_Verified" "Abundant_subunit_of_the_nuclear_pore_complex_(NPC),_present_on_both_sides_of_the_NPC,_has_similarity_to_Nup170p" YER107C GLE2 RAE1 mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 5 374541 373444 YER107C S000000909 "ORF,_Verified" "Component_of_the_nuclear_pore_complex_required_for_polyadenylated_RNA_export_but_not_for_protein_import,_homologous_to_S._pombe_Rae1p" YER109C FLO8 YER108C|PHD5 pseudohyphal_growth* specific_RNA_polymerase_II_transcription_factor_activity cytoplasm* None None 5 377610 375211 YER109C S000000911 "ORF,_Verified" "Transcription_factor_required_for_flocculation,_diploid_filamentous_growth,_and_haploid_invasive_growth;_genome_reference_strain_S288C_and_most_laboratory_strains_have_a_mutation_in_this_gene" YER110C KAP123 YRB4 protein_import_into_nucleus protein_carrier_activity cytoplasm* None None 5 382099 378758 YER110C S000000912 "ORF,_Verified" "Karyopherin_beta,_mediates_nuclear_import_of_ribosomal_proteins_prior_to_assembly_into_ribosomes_and_import_of_histones_H3_and_H4;_localizes_to_the_nuclear_pore,_nucleus,_and_cytoplasm;_exhibits_genetic_interactions_with_RAI1" YER111C SWI4 ART1 G1/S_transition_of_mitotic_cell_cycle* transcription_factor_activity nucleus M/G1 None 5 385872 382591 YER111C S000000913 "ORF,_Verified" "DNA_binding_component_of_the_SBF_complex_(Swi4p-Swi6p),_a_transcriptional_activator_that_in_concert_with_MBF_(Mbp1-Swi6p)_regulates_late_G1-specific_transcription_of_targets_including_cyclins_and_genes_required_for_DNA_synthesis_and_repair" YER112W LSM4 USS1|SDB23 "nuclear_mRNA_splicing,_via_spliceosome*" RNA_binding* nucleolus* None None 5 387228 387791 YER112W S000000914 "ORF,_Verified" "Lsm_(Like_Sm)_protein;_part_of_heteroheptameric_complexes_(Lsm2p-7p_and_either_Lsm1p_or_8p):_cytoplasmic_Lsm1p_complex_involved_in_mRNA_decay;_nuclear_Lsm8p_complex_part_of_U6_snRNP_and_possibly_involved_in_processing_tRNA,_snoRNA,_and_rRNA" YER113C TMN3 None biological_process_unknown molecular_function_unknown Golgi_apparatus* None None 5 390048 387928 YER113C S000000915 "ORF,_Verified" Protein_with_a_role_in_cellular_adhesion_and_filamentous_growth;_similar_to_Emp70p_and_Tmn2p;_member_of_Transmembrane_Nine_family_with_9_transmembrane_segments;_localizes_to_Golgi;_induced_by_8-methoxypsoralen_plus_UVA_irradiation YER117W RPL23B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 5 396765 397649 YER117W S000000919 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_identical_to_Rpl23Ap_and_has_similarity_to_E._coli_L14_and_rat_L23_ribosomal_proteins" YER118C SHO1 SSU81 pseudohyphal_growth* osmosensor_activity plasma_membrane* G1 None 5 399051 397948 YER118C S000000920 "ORF,_Verified" "Transmembrane_osmosensor,_participates_in_activation_of_both_the_Cdc42p-_and_MAP_kinase-dependent_filamentous_growth_pathway_and_the_high-osmolarity_glycerol_response_pathway" YER119C AVT6 None amino_acid_transport amino_acid_transporter_activity vacuole None None 5 400838 399492 YER119C S000000921 "ORF,_Verified" "Vacuolar_amino_acid_transporter,_exports_aspartate_and_glutamate_from_the_vacuole;_member_of_a_family_of_seven_S._cerevisiae_genes_(AVT1-7)_related_to_vesicular_GABA-glycine_transporters" YER120W SCS2 None chromatin_silencing_at_telomere* protein_binding endoplasmic_reticulum* None None 5 401131 401865 YER120W S000000922 "ORF,_Verified" "Integral_ER_membrane_protein_that_regulates_phospholipid_metabolism_via_an_interaction_with_the_FFAT_motif_of_Opi1p,_also_involved_in_telomeric_silencing,_disruption_causes_inositol_auxotrophy_above_34_degrees_C,_VAP_homolog" YER122C GLO3 None ER_to_Golgi_transport* ARF_GTPase_activator_activity COPI-coated_vesicle* None None 5 404348 402867 YER122C S000000924 "ORF,_Verified" "ADP-ribosylation_factor_GTPase_activating_protein_(ARF_GAP),_involved_in_ER-Golgi_transport;_shares_functional_similarity_with_Gcs1p" YER123W YCK3 CKI3 protein_amino_acid_phosphorylation casein_kinase_I_activity nucleus* None None 5 404809 406383 YER123W S000000925 "ORF,_Verified" "Palmitoylated,_vacuolar_membrane-localized_casein_kinase_I_isoform;_negatively_regulates_vacuole_fusion_during_hypertonic_stress_via_phosphorylation_of_the_HOPS_complex_subunit,_Vps41p;_shares_overlapping_essential_functions_with_Hrr25p" YER124C DSE1 None cell_wall_organization_and_biogenesis molecular_function_unknown bud_neck G1 None 5 409059 407338 YER124C S000000926 "ORF,_Verified" "Daughter_cell-specific_protein,_may_participate_in_pathways_regulating_cell_wall_metabolism;_deletion_affects_cell_separation_after_division_and_sensitivity_to_drugs_targeted_against_the_cell_wall" YER126C NSA2 None ribosomal_large_subunit_biogenesis molecular_function_unknown nucleus None None 5 414175 413390 YER126C S000000928 "ORF,_Verified" "Protein_constituent_of_66S_pre-ribosomal_particles,_contributes_to_processing_of_the_27S_pre-rRNA" YER127W LCP5 None rRNA_modification* RNA_binding small_nucleolar_ribonucleoprotein_complex* None None 5 414477 415550 YER127W S000000929 "ORF,_Verified" Essential_protein_involved_in_maturation_of_18S_rRNA;_depletion_leads_to_inhibited_pre-rRNA_processing_and_reduced_polysome_levels;_localizes_primarily_to_the_nucleolus YER128W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None Up 5 415855 416466 YER128W S000000930 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YER130C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 422442 421111 YER130C S000000932 "ORF,_Uncharacterized" Hypothetical_protein YER131W RPS26B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None Down 5 423948 424307 YER131W S000000933 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps26Ap_and_has_similarity_to_rat_S26_ribosomal_protein YER132C PMD1 None sporulation molecular_function_unknown cytoplasm None None 5 430445 425184 YER132C S000000934 "ORF,_Verified" "Protein_with_an_N-terminal_kelch-like_domain,_putative_negative_regulator_of_early_meiotic_gene_expression;_required,_with_Mds3p,_for_growth_under_alkaline_conditions" YER133W GLC7 DIS2S1|PP1|DIS2|CID1 35S_primary_transcript_processing* protein_phosphatase_type_1_activity nucleolus* None None 5 432491 433954 YER133W S000000935 "ORF,_Verified" "Catalytic_subunit_of_type_1_serine/threonine_protein_phosphatase,_involved_in_many_processes_including_glycogen_metabolism,_sporulation,_and_mitosis;_interacts_with_multiple_regulatory_subunits;_predominantly_isolated_with_Sds22p" YER134C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 5 437799 437263 YER134C S000000936 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene YER136W GDI1 SEC19 vesicle-mediated_transport Rab_GDP-dissociation_inhibitor_activity membrane_fraction* None None 5 439612 440967 YER136W S000000938 "ORF,_Verified" "GDP_dissociation_inhibitor,_regulates_vesicle_traffic_in_secretory_pathways_by_regulating_the_dissociation_of_GDP_from_the_Sec4/Ypt/rab_family_of_GTP_binding_proteins" YER137C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 441815 441369 YER137C S000000939 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YER137C-A None None None None None None None 5 449020 447698 YER137C-A S000007402 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YER138C None None None None None None None 5 449020 443752 YER138C S000000940 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YER138W-A None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 449470 449574 YER138W-A S000007239 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YER140W None None biological_process_unknown molecular_function_unknown mitochondrion None None 5 451560 453230 YER140W S000000942 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YER141W COX15 None cytochrome_c_oxidase_complex_assembly* "oxidoreductase_activity,_acting_on_NADH_or_NADPH,_heme_protein_as_acceptor" mitochondrial_inner_membrane None None 5 453454 454914 YER141W S000000943 "ORF,_Verified" "Protein_required_for_the_hydroxylation_of_heme_O_to_form_heme_A,_which_is_an_essential_prosthetic_group_for_cytochrome_c_oxidase" YER142C MAG1 MMS5 DNA_dealkylation alkylbase_DNA_N-glycosylase_activity nucleus None Up 5 456031 455141 YER142C S000000944 "ORF,_Verified" 3-methyl-adenine_DNA_glycosylase_involved_in_protecting_DNA_against_alkylating_agents;_initiates_base_excision_repair_by_removing_damaged_bases_to_create_abasic_sites_that_are_subsequently_repaired YER143W DDI1 VSM1 ubiquitin-dependent_protein_catabolism* SNARE_binding plasma_membrane None Up 5 456314 457600 YER143W S000000945 "ORF,_Verified" "DNA_damage-inducible_v-SNARE_binding_protein,_contains_a_ubiquitin-associated_(UBA)_domain,_may_act_as_a_negative_regulator_of_constitutive_exocytosis,_may_play_a_role_in_S-phase_checkpoint_control" YER144C UBP5 None protein_deubiquitination ubiquitin-specific_protease_activity cytoplasm None None 5 460218 457801 YER144C S000000946 "ORF,_Verified" "Putative_ubiquitin-specific_protease,_closest_paralog_of_Doa4p_but_has_no_functional_overlap;_concentrates_at_the_bud_neck" YER145C FTR1 None high_affinity_iron_ion_transport iron_ion_transporter_activity plasma_membrane G2/M None 5 461735 460521 YER145C S000000947 "ORF,_Verified" High_affinity_iron_permease_involved_in_the_transport_of_iron_across_the_plasma_membrane;_forms_complex_with_Fet3p;_expression_is_regulated_by_iron YER146W LSM5 None "nuclear_mRNA_splicing,_via_spliceosome*" RNA_binding* nucleolus* None None 5 462580 462861 YER146W S000000948 "ORF,_Verified" "Lsm_(Like_Sm)_protein;_part_of_heteroheptameric_complexes_(Lsm2p-7p_and_either_Lsm1p_or_8p):_cytoplasmic_Lsm1p_complex_involved_in_mRNA_decay;_nuclear_Lsm8p_complex_part_of_U6_snRNP_and_possibly_involved_in_processing_tRNA,_snoRNA,_and_rRNA" YER147C SCC4 None sister_chromatid_cohesion* molecular_function_unknown nuclear_chromatin None None 5 464837 462963 YER147C S000000949 "ORF,_Verified" "Subunit_of_cohesin_loading_factor_(Scc2p-Scc4p),_a_complex_required_for_the_loading_of_cohesin_complexes_onto_chromosomes;_involved_in_establishing_sister_chromatid_cohesion_during_double-strand_break_repair_via_phosphorylated_histone_H2AX" YER148W SPT15 TBP1|BTF1 transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus* None None 5 465298 466020 YER148W S000000950 "ORF,_Verified" "TATA-binding_protein,_general_transcription_factor_that_interacts_with_other_factors_to_form_the_preinitiation_complex_at_promoters,_essential_for_viability" YER149C PEA2 PPF2|DFG9 actin_filament_organization* cytoskeletal_regulatory_protein_binding actin_cap* G1 None 5 467465 466203 YER149C S000000951 "ORF,_Verified" "Coiled-coil_polarisome_protein_required_for_polarized_morphogenesis,_cell_fusion,_and_low_affinity_Ca2+_influx;_forms_polarisome_complex_with_Bni1p,_Bud6p,_and_Spa2p;_localizes_to_sites_of_polarized_growth" YER150W SPI1 None biological_process_unknown molecular_function_unknown cell_wall_(sensu_Fungi) M/G1 None 5 468365 468811 YER150W S000000952 "ORF,_Verified" GPI-anchored_cell_wall_protein_involved_in_weak_acid_resistance;_basal_expression_requires_Msn2p/Msn4p;_expression_is_induced_under_conditions_of_stress_and_during_the_diauxic_shift;_similar_to_Sed1p YER151C UBP3 BLM3 protein_deubiquitination ubiquitin-specific_protease_activity cytoplasm None None 5 472419 469681 YER151C S000000953 "ORF,_Verified" Ubiquitin-specific_protease_that_interacts_with_Bre5p_to_co-regulate_anterograde_and_retrograde_transport_between_endoplasmic_reticulum_and_Golgi_compartments;_inhibitor_of_gene_silencing;_cleaves_ubiquitin_fusions_but_not_polyubiquitin YER154W OXA1 PET1402 protein_import_into_mitochondrial_inner_membrane protein_transporter_activity mitochondrial_inner_membrane None None 5 475015 476223 YER154W S000000956 "ORF,_Verified" "Mitochondrial_inner_membrane_insertase,_mediates_the_insertion_of_both_mitochondrial-_and_nuclear-encoded_proteins_from_the_matrix_into_the_inner_membrane,_interacts_with_mitochondrial_ribosomes;_conserved_from_bacteria_to_animals" YER156C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 5 484336 483320 YER156C S000000958 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_identified_as_interacting_with_Hsp82p_in_a_high-throughput_two-hybrid_screen;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus YER158C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 490573 488852 YER158C S000000960 "ORF,_Uncharacterized" "Protein_of_unknown_function,_has_similarity_to_Afr1p;_potentially_phosphorylated_by_Cdc28p" YER159C-A None None None None None None None 5 498119 496797 YER159C-A S000007403 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YER161C SPT2 EXA1|SIN1 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter DNA_binding nucleus None None 5 500343 499342 YER161C S000000963 "ORF,_Verified" "Protein_involved_in_negative_regulation_of_transcription;_required_for_RNA_polyadenylation;_exhibits_regulated_interactions_with_both_histones_and_SWI-SNF_components,_has_similarity_to_mammalian_HMG1_proteins" YER163C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 5 503777 503079 YER163C S000000965 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus YER165W PAB1 None regulation_of_translational_initiation poly(A)_binding cytoplasm* None None 5 510368 512101 YER165W S000000967 "ORF,_Verified" "Poly(A)_binding_protein,_part_of_the_3'-end_RNA-processing_complex,_mediates_interactions_between_the_5'_cap_structure_and_the_3'_mRNA_poly(A)_tail,_involved_in_control_of_poly(A)_tail_length,_interacts_with_translation_factor_eIF-4G" YER166W DNF1 None endocytosis* phospholipid-translocating_ATPase_activity mitochondrion* None None 5 512739 517454 YER166W S000000968 "ORF,_Verified" "Aminophospholipid_translocase_(flippase)_that_localizes_primarily_to_the_plasma_membrane;_contributes_to_endocytosis,_protein_transport_and_cell_polarity;_type_4_P-type_ATPase" YER167W BCK2 CTR7 G1/S_transition_of_mitotic_cell_cycle* molecular_function_unknown cytoplasm* None None 5 518211 520766 YER167W S000000969 "ORF,_Verified" "Protein_rich_in_serine_and_threonine_residues_involved_in_protein_kinase_C_signaling_pathway,_which_controls_cell_integrity;_overproduction_suppresses_pkc1_mutations" YER168C CCA1 TNT1 tRNA_modification tRNA_adenylyltransferase_activity cytoplasm* None None 5 522664 521024 YER168C S000000970 "ORF,_Verified" "ATP_(CTP):tRNA-specific_tRNA_nucleotidyltransferase;_different_forms_targeted_to_the_nucleus,_cytosol,_and_mitochondrion_are_generated_via_the_use_of_multiple_transcriptional_and_translational_start_sites" YER173W RAD24 RS1 meiotic_recombination* DNA_clamp_loader_activity nucleus* None None 5 536295 538274 YER173W S000000975 "ORF,_Verified" "Checkpoint_protein,_involved_in_the_activation_of_the_DNA_damage_and_meiotic_pachytene_checkpoints;_subunit_of_a_clamp_loader_that_loads_Rad17p-Mec3p-Ddc1p_onto_DNA;_homolog_of_human_and_S._pombe_Rad17_protein" YER174C GRX4 None response_to_oxidative_stress thiol-disulfide_exchange_intermediate_activity intracellular None None 5 539163 538429 YER174C S000000976 "ORF,_Verified" Hydroperoxide_and_superoxide-radical_responsive_glutathione-dependent_oxidoreductase;_monothiol_glutaredoxin_subfamily_member_along_with_Grx3p_and_Grx5p;_protects_cells_from_oxidative_damage YER177W BMH1 APR6_ sporulation_(sensu_Fungi)* protein_binding* nucleus None None 5 545606 546409 YER177W S000000979 "ORF,_Verified" "14-3-3_protein,_major_isoform;_controls_proteome_at_post-transcriptional_level,_binds_proteins_and_DNA,_involved_in_regulation_of_many_processes_including_exocytosis,_vesicle_transport,_Ras/MAPK_signaling,_and_rapamycin-sensitive_signaling" YER178W PDA1 None pyruvate_metabolism pyruvate_dehydrogenase_(acetyl-transferring)_activity mitochondrion* None None 5 546812 548074 YER178W S000000980 "ORF,_Verified" "E1_alpha_subunit_of_the_pyruvate_dehydrogenase_(PDH)_complex,_catalyzes_the_direct_oxidative_decarboxylation_of_pyruvate_to_acetyl-CoA;_phosphorylated;_regulated_by_glucose" YER179W DMC1 ISC2 meiosis* single-stranded_DNA_binding* nucleus* None None 5 548416 549512 YER179W S000000981 "ORF,_Verified" Meiosis-specific_protein_required_for_repair_of_double-strand_breaks_and_pairing_between_homologous_chromosomes;_homolog_of_Rad51p_and_the_bacterial_RecA_protein YER180C ISC10 None sporulation molecular_function_unknown cellular_component_unknown None None 5 550522 549719 YER180C S000000982 "ORF,_Verified" "Protein_required_for_sporulation,_transcript_is_induced_7.5_hours_after_induction_of_meiosis,_expected_to_play_significant_role_in_the_formation_of_reproductive_cells" YER182W None None biological_process_unknown molecular_function_unknown mitochondrion None None 5 552520 553254 YER182W S000000984 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YER183C FAU1 None folic_acid_and_derivative_biosynthesis 5-formyltetrahydrofolate_cyclo-ligase_activity mitochondrion None None 5 553964 553329 YER183C S000000985 "ORF,_Verified" "5,10-methenyltetrahydrofolate_synthetase,_involved_in_folic_acid_biosynthesis" YER185W PUG1 None biological_process_unknown molecular_function_unknown integral_to_membrane None None 5 559449 560360 YER185W S000000987 "ORF,_Verified" Plasma_membrane_protein_with_roles_in_the_uptake_of_protoprophyrin_IX_and_the_efflux_of_heme;_expression_is_induced_under_both_low-heme_and_low-oxygen_conditions YER187W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 5 566225 566650 YER187W S000000989 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_induced_in_respiratory-deficient_cells YER189W None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 5 571150 571518 YER189W S000000991 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YER190W YRF1-2 YRF1 telomerase-independent_telomere_maintenance DNA_helicase_activity nucleus G1 None 5 571475 576520 YER190W S000000992 "ORF,_Verified" "Helicase_encoded_by_the_Y'_element_of_subtelomeric_regions,_highly_expressed_in_the_mutants_lacking_the_telomerase_component_TLC1;_potentially_phosphorylated_by_Cdc28p;_induced_by_treatment_with_8-methoxypsoralen_and_UVA_irradiation" YFL002C SPB4 None 35S_primary_transcript_processing* ATP-dependent_RNA_helicase_activity nucleolus None None 6 146929 145109 YFL002C S000001894 "ORF,_Verified" "Putative_ATP-dependent_RNA_helicase,_nucleolar_protein_required_for_synthesis_of_60S_ribosomal_subunits_at_a_late_step_in_the_pathway;_sediments_with_66S_pre-ribosomes_in_sucrose_gradients" YFL002W-A None None None None None None None 6 138199 143512 YFL002W-A S000002962 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YFL002W-B None None None None None None None 6 138199 139515 YFL002W-B S000007404 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YFL004W VTC2 PHM1 "vacuole_fusion,_non-autophagic*" molecular_function_unknown vacuolar_membrane None None 6 131805 134291 YFL004W S000001890 "ORF,_Verified" Vacuolar_membrane_protein_involved_in_vacuolar_polyphosphate_accumulation;_functions_as_a_regulator_of_vacuolar_H+-ATPase_activity_and_vacuolar_transporter_chaperones;_involved_in_protein_localization_and_non-autophagic_vacuolar_fusion YFL007W BLM10 YFL006W protein_catabolism* proteasome_activator_activity nucleus* None Up 6 123474 129905 YFL007W S000001887 "ORF,_Verified" "Proteosome_activator_subunit;_found_in_association_with_core_particles,_with_and_without_the_19S_regulatory_particle;_required_for_resistance_to_bleomycin,_may_be_involved_in_protecting_against_oxidative_damage;_similar_to_mammalian_PA200" YFL008W SMC1 CHL10 mitotic_sister_chromatid_segregation* ATPase_activity* nuclear_cohesin_complex G1 None 6 119424 123101 YFL008W S000001886 "ORF,_Verified" "Subunit_of_the_multiprotein_cohesin_complex,_essential_protein_involved_in_chromosome_segregation_and_in_double-strand_DNA_break_repair;_SMC_chromosomal_ATPase_family_member,_binds_DNA_with_a_preference_for_DNA_with_secondary_structure" YFL009W CDC4 None G1/S_transition_of_mitotic_cell_cycle* protein_binding* nuclear_SCF_ubiquitin_ligase_complex None None 6 116139 118478 YFL009W S000001885 "ORF,_Verified" "F-box_protein_required_for_G1/S_and_G2/M_transition,_associates_with_Skp1p_and_Cdc53p_to_form_a_complex,_SCFCdc4,_which_acts_as_ubiquitin-protein_ligase_directing_ubiquitination_of_the_phosphorylated_CDK_inhibitor_Sic1p" YFL010C WWM1 None response_to_desiccation molecular_function_unknown cytoplasm* None None 6 115737 115102 YFL010C S000001884 "ORF,_Verified" "WW_domain_containing_protein_of_unknown_function;_binds_to_Mca1p,_a_caspase-related_protease_that_regulates_H2O2-induced_apoptosis;_overexpression_causes_Gi_phase_growth_arrest_and_clonal_death_that_is_suppressed_by_overexpression_of_MCA1" YFL010W-A AUA1 YFL011W-A amino_acid_transport molecular_function_unknown cellular_component_unknown None None 6 114984 115268 YFL010W-A S000001955 "ORF,_Verified" "Protein_required_for_the_negative_regulation_by_ammonia_of_Gap1p,_which_is_a_general_amino_acid_permease" YFL011W HXT10 None hexose_transport glucose_transporter_activity* mitochondrion* M/G1 None 6 112339 113979 YFL011W S000001883 "ORF,_Verified" "Putative_hexose_transporter,_expressed_at_low_levels_and_expression_is_repressed_by_glucose" YFL013C IES1 None chromatin_remodeling molecular_function_unknown nucleus* None None 6 109924 107846 YFL013C S000001881 "ORF,_Verified" Subunit_of_the_INO80_chromatin_remodeling_complex YFL014W HSP12 HOR5|GLP1 response_to_oxidative_stress* molecular_function_unknown cytoplasm* None Up 6 107250 107579 YFL014W S000001880 "ORF,_Verified" "Plasma_membrane_localized_protein_that_protects_membranes_from_desiccation;_induced_by_heat_shock,_oxidative_stress,_osmostress,_stationary_phase_entry,_glucose_depletion,_oleate_and_alcohol;_regulated_by_the_HOG_and_Ras-Pka_pathways" YFL016C MDJ1 None protein_folding* unfolded_protein_binding* mitochondrial_inner_membrane None None 6 106230 104695 YFL016C S000001878 "ORF,_Verified" Co-chaperone_that_stimulates_the_ATPase_activity_of_the_HSP70_protein_Ssc1p;_involved_in_protein_folding/refolding_in_the_mitochodrial_matrix;_required_for_proteolysis_of_misfolded_proteins;_member_of_the_HSP40_(DnaJ)_family_of_chaperones YFL017C GNA1 PAT1 UDP-N-acetylglucosamine_biosynthesis glucosamine_6-phosphate_N-acetyltransferase_activity cytoplasm* None None 6 104456 103977 YFL017C S000001877 "ORF,_Verified" "Evolutionarily_conserved_glucosamine-6-phosphate_acetyltransferase_required_for_multiple_cell_cycle_events_including_passage_through_START,_DNA_synthesis,_and_mitosis;_involved_in_UDP-N-acetylglucosamine_synthesis,_forms_GlcNAc6P_from_AcCoA" YFL017W-A SMX2 YFL018W-A|SNP2 "nuclear_mRNA_splicing,_via_spliceosome" "RNA_splicing_factor_activity,_transesterification_mechanism" U4/U6_x_U5_tri-snRNP_complex* None None 6 103693 103926 YFL017W-A S000002965 "ORF,_Verified" "Core_Sm_protein_Sm_G;_part_of_heteroheptameric_complex_(with_Smb1p,_Smd1p,_Smd2p,_Smd3p,_Sme1p,_and_Smx3p)_that_is_part_of_the_spliceosomal_U1,_U2,_U4,_and_U5_snRNPs;_homolog_of_human_Sm_G" YFL018C LPD1 HPD1 glycine_catabolism* glycine_dehydrogenase_(decarboxylating)_activity* mitochondrial_nucleoid* None None 6 103121 101622 YFL018C S000001876 "ORF,_Verified" "Dihydrolipoamide_dehydrogenase,_the_lipoamide_dehydrogenase_component_(E3)_of_the_pyruvate_dehydrogenase_and_2-oxoglutarate_dehydrogenase_multi-enzyme_complexes" YFL020C PAU5 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 99593 99225 YFL020C S000001874 "ORF,_Verified" "Part_of_23-member_seripauperin_multigene_family_encoded_mainly_in_subtelomeric_regions,_active_during_alcoholic_fermentation,_regulated_by_anaerobiosis,_negatively_regulated_by_oxygen,_repressed_by_heme" YFL021W GAT1 MEP80|NIL1 transcription_initiation_from_RNA_polymerase_II_promoter* specific_RNA_polymerase_II_transcription_factor_activity* nucleus* None None 6 95964 97496 YFL021W S000001873 "ORF,_Verified" Transcriptional_activator_of_genes_involved_in_nitrogen_catabolite_repression;_contains_a_GATA-1-type_zinc_finger_DNA-binding_motif;_activity_and_localization_regulated_by_nitrogen_limitation_and_Ure2p YFL022C FRS2 None phenylalanyl-tRNA_aminoacylation phenylalanine-tRNA_ligase_activity cytoplasm* None None 6 95008 93497 YFL022C S000001872 "ORF,_Verified" "Alpha_subunit_of_cytoplasmic_phenylalanyl-tRNA_synthetase,_forms_a_tetramer_with_Frs1p_to_form_active_enzyme;_evolutionarily_distant_from_mitochondrial_phenylalanyl-tRNA_synthetase_based_on_protein_sequence,_but_substrate_binding_is_similar" YFL023W BUD27 URI1 bud_site_selection molecular_function_unknown cytoplasm None None 6 90984 93374 YFL023W S000001871 "ORF,_Verified" "Protein_involved_in_bud-site_selection,_nutrient_signaling,_and_gene_expression_controlled_by_TOR_kinase;_diploid_mutants_show_a_random_budding_pattern_rather_than_the_wild-type_bipolar_pattern;_plays_a_role_in_regulating_Ty1_transposition" YFL024C EPL1 None regulation_of_transcription_from_RNA_polymerase_II_promoter* histone_acetyltransferase_activity histone_acetyltransferase_complex* None None 6 90343 87845 YFL024C S000001870 "ORF,_Verified" "Component_of_NuA4,_which_is_an_essential_histone_H4/H2A_acetyltransferase_complex;_homologous_to_Drosophila_Enhancer_of_Polycomb" YFL025C BST1 PER17 ER_to_Golgi_transport* carboxylic_ester_hydrolase_activity endoplasmic_reticulum* None None 6 87232 84143 YFL025C S000001869 "ORF,_Verified" "GPI_inositol_deacylase_of_the_ER_that_negatively_regulates_COPII_vesicle_formation,_prevents_production_of_vesicles_with_defective_subunits,_required_for_proper_discrimination_between_resident_ER_proteins_and_Golgi-bound_cargo_molecules" YFL026W STE2 None response_to_pheromone_during_conjugation_with_cellular_fusion* mating-type_alpha-factor_pheromone_receptor_activity integral_to_plasma_membrane M/G1 None 6 82578 83873 YFL026W S000001868 "ORF,_Verified" Receptor_for_alpha-factor_pheromone;_seven_transmembrane-domain_GPCR_that_interacts_with_both_pheromone_and_a_heterotrimeric_G_protein_to_initiate_the_signaling_response_that_leads_to_mating_between_haploid_a_and_alpha_cells YFL030W AGX1 None glycine_biosynthesis alanine-glyoxylate_transaminase_activity mitochondrion None Up 6 76829 77986 YFL030W S000001864 "ORF,_Verified" "Alanine:glyoxylate_aminotransferase_(AGT),_catalyzes_the_synthesis_of_glycine_from_glyoxylate,_which_is_one_of_three_pathways_for_glycine_biosynthesis_in_yeast;_has_similarity_to_mammalian_and_plant_alanine:glyoxylate_aminotransferases" YFL031W HAC1 IRE15|ERN4 regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_factor_activity* nucleus None None 6 75177 76145 YFL031W S000001863 "ORF,_Verified" "Basic_leucine_zipper_(bZIP)_transcription_factor_(ATF/CREB1_homolog)_that_regulates_the_unfolded_protein_response,_via_UPRE_binding,_and_membrane_biogenesis;_ER_stress-induced_splicing_pathway_facilitates_efficient_Hac1p_synthesis" YFL033C RIM15 TAK1 protein_amino_acid_phosphorylation* protein_kinase_activity cytoplasm* None None 6 74425 69113 YFL033C S000001861 "ORF,_Verified" "Glucose-repressible_protein_kinase_involved_in_signal_transduction_during_cell_proliferation_in_response_to_nutrients,_specifically_the_establishment_of_stationary_phase;_identified_as_a_regulator_of_IME2;_substrate_of_Pho80p-Pho85p_kinase" YFL034C-A RPL22B YFL035C-B protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 6 64931 64242 YFL034C-A S000006436 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_Rpl22Ap_and_to_rat_L22_ribosomal_protein" YFL034C-B MOB2 YFL035C-A|YFL035C protein_amino_acid_phosphorylation* protein_kinase_activator_activity nucleus* None None 6 63992 63015 YFL034C-B S000001859 "ORF,_Verified" "Component_of_the_RAM_signaling_network,_localizes_and_activates_the_Ace2p_in_the_daughter_cell_nucleus_to_direct_daughter_cell-specific_transcription_of_several_genes_involved_in_cell_separation;_Mob1p-like_protein" YFL034W None None biological_process_unknown molecular_function_unknown integral_to_membrane None None 6 65475 68696 YFL034W S000001860 "ORF,_Uncharacterized" "Putative_integral_membrane_protein_that_interacts_with_Rpp0p,_which_is_a_component_of_the_ribosomal_stalk" YFL036W RPO41 None mitochondrial_genome_maintenance* DNA-directed_RNA_polymerase_activity mitochondrial_matrix* None None 6 58781 62836 YFL036W S000001858 "ORF,_Verified" Mitochondrial_RNA_polymerase;_single_subunit_enzyme_similar_to_those_of_T3_and_T7_bacteriophages;_requires_a_specificity_subunit_encoded_by_MTF1_for_promoter_recognition YFL037W TUB2 SHE8|ARM10 mitotic_sister_chromatid_segregation* structural_constituent_of_cytoskeleton spindle_pole_body* S/G2 None 6 56335 57708 YFL037W S000001857 "ORF,_Verified" "Beta-tubulin;_associates_with_alpha-tubulin_(Tub1p_and_Tub3p)_to_form_tubulin_dimer,_which_polymerizes_to_form_microtubules" YFL038C YPT1 YP2 ER_to_Golgi_transport* GTPase_activity mitochondrion* None None 6 55985 55365 YFL038C S000001856 "ORF,_Verified" "Ras-like_small_GTPase,_involved_in_the_ER-to-Golgi_step_of_the_secretory_pathway;_complex_formation_with_the_Rab_escort_protein_Mrs6p_is_required_for_prenylation_of_Ypt1p_by_protein_geranylgeranyltransferase_type_II_(Bet2p-Bet4p)" YFL042C None YFL043C biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 47744 45720 YFL042C S000001852 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YFL042C_is_not_an_essential_gene YFL044C OTU1 YOD1 regulation_of_transcription molecular_function_unknown cytoplasm* M/G1 None 6 45560 44655 YFL044C S000001850 "ORF,_Verified" Deubiquitylation_enzyme_that_binds_to_the_chaperone-ATPase_Cdc48p;_may_contribute_to_regulation_of_protein_degradation_by_deubiquitylating_substrates_that_have_been_ubiquitylated_by_Ufd2p;_member_of_the_Ovarian_Tumor_(OTU)_family YFL045C SEC53 ALG4 protein_targeting_to_ER phosphomannomutase_activity cytosol None None 6 44392 43628 YFL045C S000001849 "ORF,_Verified" "Phosphomannomutase,_involved_in_synthesis_of_GDP-mannose_and_dolichol-phosphate-mannose;_required_for_folding_and_glycosylation_of_secretory_proteins_in_the_ER_lumen" YFL047W RGD2 None small_GTPase_mediated_signal_transduction Rho_GTPase_activator_activity cytoplasm* None None 6 40421 42565 YFL047W S000001847 "ORF,_Verified" GTPase-activating_protein_(RhoGAP)_for_Cdc42p_and_Rho5p YFL048C EMP47 None ER_to_Golgi_transport molecular_function_unknown Golgi_apparatus* None None 6 40180 38843 YFL048C S000001846 "ORF,_Verified" "Integral_membrane_component_of_endoplasmic_reticulum-derived_COPII-coated_vesicles,_which_function_in_ER_to_Golgi_transport" YFL052W None None biological_process_unknown DNA_binding cellular_component_unknown None None 6 28232 29629 YFL052W S000001842 "ORF,_Uncharacterized" "Putative_zinc_cluster_protein_that_contains_a_DNA_binding_domain;_null_mutant_sensitive_to_calcofluor_white,_low_osmolarity_and_heat,_suggesting_a_role_for_YFL052Wp_in_cell_wall_integrity" YFL056C AAD6 None aldehyde_metabolism aryl-alcohol_dehydrogenase_activity cellular_component_unknown None Up 6 15431 14793 YFL056C S000001838 "ORF,_Verified" "Putative_aryl-alcohol_dehydrogenase_with_similarity_to_P._chrysosporium_aryl-alcohol_dehydrogenase,_involved_in_the_oxidative_stress_response" YFL057C AAD16 None aldehyde_metabolism aryl-alcohol_dehydrogenase_activity cellular_component_unknown None Up 6 14763 14305 YFL057C S000001837 "ORF,_Verified" Putative_aryl-alcohol_dehydrogenase_with_similarity_to_P._chrysosporium_aryl-alcohol_dehydrogenase;_mutational_analysis_has_not_yet_revealed_a_physiological_role YFL058W THI5 None thiamin_biosynthesis molecular_function_unknown cellular_component_unknown None None 6 12929 13951 YFL058W S000001836 "ORF,_Verified" "Protein_involved_in_synthesis_of_the_thiamine_precursor_hydroxymethylpyrimidine_(HMP);_member_of_a_subtelomeric_gene_family_including_THI5,_THI11,_THI12,_and_THI13" YFL059W SNZ3 None thiamin_biosynthesis* protein_binding cellular_component_unknown None None 6 11363 12259 YFL059W S000001835 "ORF,_Verified" "Member_of_a_stationary_phase-induced_gene_family;_transcription_of_SNZ2_is_induced_prior_to_diauxic_shift,_and_also_in_the_absence_of_thiamin_in_a_Thi2p-dependent_manner;_forms_a_coregulated_gene_pair_with_SNO3" YFL060C SNO3 None thiamin_biosynthesis* molecular_function_unknown cellular_component_unknown G1 None 6 10969 10301 YFL060C S000001834 "ORF,_Verified" "Protein_of_unknown_function,_nearly_identical_to_Sno2p;_expression_is_induced_before_the_diauxic_shift_and_also_in_the_absence_of_thiamin" YFL062W COS4 None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) None None 6 6426 7565 YFL062W S000001832 "ORF,_Verified" "Protein_of_unknown_function,_member_of_the_DUP380_subfamily_of_conserved,_often_subtelomerically-encoded_proteins" YFL064C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 6 3846 3322 YFL064C S000001830 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YFL066C None None biological_process_unknown molecular_function_unknown cellular_component_unknown M/G1 None 6 2615 1437 YFL066C S000001828 "ORF,_Uncharacterized" Helicase-like_protein_encoded_within_the_telomeric_Y'_element;_induced_by_treatment_with_8-methoxypsoralen_and_UVA_irradiation YFL067W None None biological_process_unknown molecular_function_unknown cellular_component_unknown M/G1 None 6 836 1363 YFL067W S000001827 "ORF,_Uncharacterized" "Protein_of_unknown_function,_down-regulated_at_low_calcium_levels" YFL068W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 53 535 YFL068W S000001826 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YFR001W LOC1 None ribosomal_large_subunit_biogenesis* mRNA_binding nucleus None None 6 149105 149719 YFR001W S000001897 "ORF,_Verified" Nuclear_protein_involved_in_asymmetric_localization_of_ASH1_mRNA;_binds_double-stranded_RNA_in_vitro;_constituent_of_66S_pre-ribosomal_particles YFR003C YPI1 None protein_amino_acid_dephosphorylation* protein_phosphatase_inhibitor_activity cellular_component_unknown None None 6 153119 152652 YFR003C S000001899 "ORF,_Verified" "Inhibitor_of_the_type_I_protein_phosphatase_Glc7p,_which_is_involved_in_regulation_of_a_variety_of_metabolic_processes;_overproduction_causes_decreased_cellular_content_of_glycogen" YFR004W RPN11 MPR1 ubiquitin-dependent_protein_catabolism endopeptidase_activity nucleus* None None 6 153388 154308 YFR004W S000001900 "ORF,_Verified" Metalloprotease_subunit_of_the_19S_regulatory_particle_of_the_26S_proteasome_lid;_couples_the_deubiquitination_and_degradation_of_proteasome_substrates YFR005C SAD1 None "nuclear_mRNA_splicing,_via_spliceosome" "RNA_splicing_factor_activity,_transesterification_mechanism" nucleus None None 6 155868 154522 YFR005C S000001901 "ORF,_Verified" "Conserved_zinc-finger_domain_protein_involved_in_pre-mRNA_splicing,_required_for_assembly_of_U4_snRNA_into_the_U4/U6_particle" YFR006W None None biological_process_unknown X-Pro_aminopeptidase_activity cytoplasm None None 6 156139 157746 YFR006W S000001902 "ORF,_Uncharacterized" Putative_X-Pro_aminopeptidase;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YFR006W_is_not_an_essential_gene YFR007W YFH7 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 159293 160354 YFR007W S000001903 "ORF,_Verified" Putative_kinase_with_similarity_to_the_phosphoribulokinase/uridine_kinase/bacterial_pantothenate_kinase_(PRK/URK/PANK)_subfamily_of_P-loop_kinases;_null_mutant_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation) YFR008W FAR7 None cell_cycle_arrest_in_response_to_pheromone molecular_function_unknown cellular_component_unknown None None 6 160529 161194 YFR008W S000001904 "ORF,_Verified" "Protein_involved_in_G1_cell_cycle_arrest_in_response_to_pheromone,_in_a_pathway_different_from_the_Far1p-dependent_pathway;_interacts_with_Far3p,_Far8p,_Far9p,_Far10p,_and_Far11p" YFR009W GCN20 None regulation_of_translational_elongation ATPase_activity cytosol* None None 6 162482 164740 YFR009W S000001905 "ORF,_Verified" "Positive_regulator_of_the_Gcn2p_kinase_activity,_forms_a_complex_with_Gcn1p;_proposed_to_stimulate_Gcn2p_activation_by_an_uncharged_tRNA" YFR010W UBP6 None protein_deubiquitination ubiquitin-specific_protease_activity proteasome_regulatory_particle_(sensu_Eukaryota) None Up 6 165060 166559 YFR010W S000001906 "ORF,_Verified" "Ubiquitin-specific_protease_situated_in_the_base_subcomplex_of_the_26S_proteasome,_releases_free_ubiquitin_from_branched_polyubiquitin_chains;_works_in_opposition_to_polyubiquitin_elongation_activity_of_Hul5p" YFR011C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 6 167251 166739 YFR011C S000001907 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-tagged_protein_is_detected_in_highly_purified_mitochondria;_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation)_and_reduced_growth_rate_in_minimal_glycerol_media YFR012W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 167881 168489 YFR012W S000001908 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YFR013W IOC3 None chromatin_remodeling protein_binding ISW1_complex None None 6 169914 172277 YFR013W S000001909 "ORF,_Verified" "Member_of_a_complex_(Isw1a)_with_Isw1p_that_has_nucleosome-stimulated_ATPase_activity_and_represses_transcription_initiation_by_specific_positioning_of_a_promoter_proximal_dinucleosome;_has_homology_to_Esc8p,_which_is_involved_in_silencing" YFR014C CMK1 None protein_amino_acid_phosphorylation* calmodulin-dependent_protein_kinase_I_activity cytoplasm None None 6 173869 172529 YFR014C S000001910 "ORF,_Verified" "Calmodulin-dependent_protein_kinase;_may_play_a_role_in_stress_response,_many_CA++/calmodulan_dependent_phosphorylation_substrates_demonstrated_in_vitro,_amino_acid_sequence_similar_to_Cmk2p_and_mammalian_Cam_Kinase_II" YFR015C GSY1 None glycogen_biosynthesis glycogen_(starch)_synthase_activity cytoplasm* M/G1 None 6 176383 174257 YFR015C S000001911 "ORF,_Verified" "Glycogen_synthase_with_similarity_to_Gsy2p,_the_more_highly_expressed_yeast_homolog;_expression_induced_by_glucose_limitation,_nitrogen_starvation,_environmental_stress,_and_entry_into_stationary_phase" YFR016C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 6 180735 177034 YFR016C S000001912 "ORF,_Verified" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_bud;_interacts_with_Spa2p;_YFL016C_is_not_an_essential_gene YFR017C None None biological_process_unknown molecular_function_unknown cytoplasm None None 6 182849 182262 YFR017C S000001913 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_is_induced_in_response_to_the_DNA-damaging_agent_MMS;_YFR017C_is_not_an_essential_gene YFR019W FAB1 SVL7 response_to_stress* 1-phosphatidylinositol-3-phosphate_5-kinase_activity mitochondrion* None None 6 184490 191326 YFR019W S000001915 "ORF,_Verified" "1-phosphatidylinositol-3-phosphate_5-kinase;_vacuolar_membrane_kinase_that_generates_phosphatidylinositol_(3,5)P2,_which_is_involved_in_vacuolar_sorting_and_homeostasis" YFR021W ATG18 SVP1|AUT10|CVT18|NMR1 protein_targeting_to_vacuole* phosphoinositide_binding cytosol* None None 6 194800 196302 YFR021W S000001917 "ORF,_Verified" "Phosphoinositide_binding_protein_required_for_vesicle_formation_in_autophagy_and_the_cytoplasm-to-vacuole_targeting_(Cvt)_pathway;_binds_both_phosphatidylinositol_(3,5)-bisphosphate_and_phosphatidylinositol_3-phosphate;_WD-40_repeat_protein" YFR022W ROG3 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 196821 199022 YFR022W S000001918 "ORF,_Verified" "Protein_that_binds_to_Rsp5p,_which_is_a_hect-type_ubiquitin_ligase,_via_its_2_PY_motifs;_has_similarity_to_Rod1p;_mutation_suppresses_the_temperature_sensitivity_of_an_mck1_rim11_double_mutant" YFR024C-A LSB3 YFR024C actin_filament_organization molecular_function_unknown cytoplasm* None None 6 203421 201948 YFR024C-A S000002968 "ORF,_Verified" "Protein_containing_a_C-terminal_SH3_domain;_binds_Las17p,_which_is_a_homolog_of_human_Wiskott-Aldrich_Syndrome_protein_involved_in_actin_patch_assembly_and_actin_polymerization" YFR025C HIS2 None histidine_biosynthesis histidinol-phosphatase_activity intracellular None None 6 204738 203731 YFR025C S000001921 "ORF,_Verified" "Histidinolphosphatase,_catalyzes_the_eighth_step_in_histidine_biosynthesis;_mutations_cause_histidine_auxotrophy_and_sensitivity_to_Cu,_Co,_and_Ni_salts;_transcription_is_regulated_by_general_amino_acid_control" YFR026C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 206245 205736 YFR026C S000001922 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YFR027W ECO1 CTF7 DNA_repair* acetyltransferase_activity nuclear_chromatin G1 None 6 207440 208285 YFR027W S000001923 "ORF,_Verified" Acetyltransferase_required_for_Smc3p_acetylation_during_the_establishment_of_sister_chromatid_cohesion_during_DNA_replication;_required_in_response_to_double-strand_breaks_and_during_postreplicative_double-strand_break_repair YFR028C CDC14 OAF3 protein_amino_acid_dephosphorylation* phosphoprotein_phosphatase_activity nucleus* S/G2 None 6 210056 208401 YFR028C S000001924 "ORF,_Verified" "Protein_phosphatase_required_for_mitotic_exit;_located_in_the_nucleolus_until_liberated_by_the_FEAR_and_Mitotic_Exit_Network_in_anaphase,_enabling_it_to_act_on_key_substrates_to_effect_a_decrease_in_CDK/B-cyclin_activity_and_mitotic_exit" YFR030W MET10 None sulfate_assimilation sulfite_reductase_(NADPH)_activity cytoplasm* S Up 6 213300 216407 YFR030W S000001926 "ORF,_Verified" "Subunit_alpha_of_assimilatory_sulfite_reductase,_which_is_responsible_for_the_conversion_of_sulfite_into_sulfide" YFR031C SMC2 None mitotic_sister_chromatid_segregation* ATPase_activity* mitochondrion* None None 6 220094 216582 YFR031C S000001927 "ORF,_Verified" "Component_of_the_condensin_complex,_essential_SMC_chromosomal_ATPase_family_member_that_forms_a_complex_with_Smc4p_to_form_the_active_ATPase;_Smc2p/Smc4p_complex_binds_DNA,_possibly_in_the_cleft_formed_by_the_coiled-coil_of_the_folded_dimer" YFR031C-A RPL2A RPL5B protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 6 221406 220495 YFR031C-A S000002104 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_identical_to_Rpl2Bp_and_has_similarity_to_E._coli_L2_and_rat_L8_ribosomal_proteins" YFR032C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 222947 222078 YFR032C S000001928 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_transcribed_during_sporulation;_YFR032C_is_not_an_essential_gene YFR032C-A RPL29 None protein_biosynthesis structural_constituent_of_ribosome cytoplasm* None None 6 223425 223246 YFR032C-A S000006437 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_rat_L29_ribosomal_protein;_not_essential_for_translation,_but_required_for_proper_joining_of_the_large_and_small_ribosomal_subunits_and_for_normal_translation_rate" YFR033C QCR6 UCR6|COR3 aerobic_respiration* ubiquinol-cytochrome-c_reductase_activity mitochondrion* None None 6 224757 224314 YFR033C S000001929 "ORF,_Verified" "Subunit_6_of_the_ubiquinol_cytochrome-c_reductase_complex,_which_is_a_component_of_the_mitochondrial_inner_membrane_electron_transport_chain;_highly_acidic_protein;_required_for_maturation_of_cytochrome_c1" YFR034C PHO4 phoD phosphate_metabolism* transcription_factor_activity cytoplasm* None None 6 225946 225008 YFR034C S000001930 "ORF,_Verified" Basic_helix-loop-helix_(bHLH)_transcription_factor_of_the_myc-family;_binds_cooperatively_with_Pho2p_to_the_PHO5_promoter;_function_is_regulated_by_phosphorylation_at_multiple_sites_and_by_phosphate_availability YFR035C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 226453 226109 YFR035C S000001931 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_deletion_mutant_exhibits_synthetic_phenotype_with_alpha-synuclein" YFR036W CDC26 SCD26|HIT3 mitotic_sister_chromatid_segregation* protein_binding* anaphase-promoting_complex None None 6 226950 227324 YFR036W S000001932 "ORF,_Verified" "Subunit_of_the_Anaphase-Promoting_Complex/Cyclosome_(APC/C),_which_is_a_ubiquitin-protein_ligase_required_for_degradation_of_anaphase_inhibitors,_including_mitotic_cyclins,_during_the_metaphase/anaphase_transition" YFR037C RSC8 SWH3 chromatin_remodeling* molecular_function_unknown nucleus* None None 6 229173 227500 YFR037C S000001933 "ORF,_Verified" "Component_of_the_RSC_chromatin_remodeling_complex;_essential_for_viability_and_mitotic_growth;_homolog_of_SWI/SNF_subunit_Swi3p,_but_unlike_Swi3p,_does_not_activate_transcription_of_reporters" YFR038W IRC5 None biological_process_unknown helicase_activity cellular_component_unknown None None 6 229367 231928 YFR038W S000001934 "ORF,_Verified" Putative_ATPase_containing_the_DEAD/H_helicase-related_sequence_motif;_null_mutant_displays_increased_levels_of_spontaneous_Rad52p_foci YFR039C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G2/M None 6 233531 231999 YFR039C S000001935 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_may_be_involved_in_response_to_high_salt_and_changes_in_carbon_source;_deletion_mutant_has_decreased_spore_survival_in_Drosophila_feces YFR040W SAP155 None G1/S_transition_of_mitotic_cell_cycle protein_serine/threonine_phosphatase_activity cytoplasm None None 6 234229 237237 YFR040W S000001936 "ORF,_Verified" "Protein_that_forms_a_complex_with_the_Sit4p_protein_phosphatase_and_is_required_for_its_function;_member_of_a_family_of_similar_proteins_including_Sap4p,_Sap185p,_and_Sap190p" YFR042W KEG1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 238445 239047 YFR042W S000001938 "ORF,_Verified" "Integral_membrane_protein_of_the_ER;_physically_interacts_with_Kre6p;_has_a_role_in_the_synthesis_of_beta-1,6-glucan_in_the_cell_wall;_required_for_cell_viability" YFR043C IRC6 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 239814 239101 YFR043C S000001939 "ORF,_Verified" Putative_protein_of_unknown_function;_null_mutant_displays_increased_levels_of_spontaneous_Rad52p_foci YFR044C DUG1 None biological_process_unknown molecular_function_unknown cytoplasm* None None 6 241424 239979 YFR044C S000001940 "ORF,_Verified" Probable_di-_and_tri-peptidase;_forms_a_complex_with_Dug2p_and_Dug3p_to_degrade_glutathione_(GSH)_and_other_peptides_containing_a_gamma-glu-X_bond_in_an_alternative_pathway_to_GSH_degradation_by_gamma-glutamyl_transpeptidase_(Ecm38p) YFR045W None None transport transporter_activity mitochondrial_inner_membrane None None 6 241985 242986 YFR045W S000001941 "ORF,_Uncharacterized" "Putative_mitochondrial_transport_protein;_null_mutant_is_viable,_exhibits_decreased_levels_of_chitin_and_normal_resistance_to_calcofluor_white" YFR046C CNN1 None chromosome_segregation molecular_function_unknown nucleus* None None 6 244146 243061 YFR046C S000001942 "ORF,_Verified" "Kinetochore_protein_of_unknown_function;_associated_with_the_essential_kinetochore_proteins_Nnf1p_and_Spc24p;_phosphorylated_by_both_Clb5-Cdk1_and,_to_a_lesser_extent,_Clb2-Cdk1." YFR047C BNA6 QPT1 NAD_biosynthesis nicotinate-nucleotide_diphosphorylase_(carboxylating)_activity cytoplasm* None None 6 245153 244266 YFR047C S000001943 "ORF,_Verified" "Quinolinate_phosphoribosyl_transferase,_required_for_the_de_novo_biosynthesis_of_NAD_from_tryptophan_via_kynurenine;_expression_regulated_by_Hst1p" YFR048W RMD8 None biological_process_unknown molecular_function_unknown cytoplasm None None 6 246133 248121 YFR048W S000001944 "ORF,_Verified" Cytosolic_protein_required_for_sporulation YFR049W YMR31 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 6 248510 248881 YFR049W S000001945 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_small_subunit,_has_similarity_to_human_mitochondrial_ribosomal_protein_MRP-S36" YFR050C PRE4 None ubiquitin-dependent_protein_catabolism endopeptidase_activity "proteasome_core_complex,_beta-subunit_complex_(sensu_Eukaryota)" None None 6 249853 249053 YFR050C S000001946 "ORF,_Verified" Beta_7_subunit_of_the_20S_proteasome YFR051C RET2 None ER_to_Golgi_transport* protein_binding COPI_vesicle_coat None None 6 251790 250150 YFR051C S000001947 "ORF,_Verified" "Delta_subunit_of_the_coatomer_complex_(COPI),_which_coats_Golgi-derived_transport_vesicles;_involved_in_retrograde_transport_between_Golgi_and_ER" YFR053C HXK1 None glucose_metabolism* hexokinase_activity cytosol None None 6 255036 253579 YFR053C S000001949 "ORF,_Verified" "Hexokinase_isoenzyme_1,_a_cytosolic_protein_that_catalyzes_phosphorylation_of_glucose_during_glucose_metabolism;_expression_is_highest_during_growth_on_non-glucose_carbon_sources;_glucose-induced_repression_involves_the_hexokinase_Hxk2p" YFR055W IRC7 None sulfur_metabolism* cystathionine_beta-lyase_activity cellular_component_unknown None Up 6 264191 265213 YFR055W S000001952 "ORF,_Uncharacterized" "Putative_cystathionine_beta-lyase;_involved_in_copper_ion_homeostasis_and_sulfur_metabolism;_null_mutant_displays_increased_levels_of_spontaneous_Rad52p_foci;_expression_induced_by_nitrogen_limitation_in_a_GLN3,_GAT1-dependent_manner" YFR057W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 6 269048 269503 YFR057W S000001953 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YGL001C ERG26 None ergosterol_biosynthesis C-3_sterol_dehydrogenase_(C-4_sterol_decarboxylase)_activity endoplasmic_reticulum* None None 7 496506 495457 YGL001C S000002969 "ORF,_Verified" "C-3_sterol_dehydrogenase,_catalyzes_the_second_of_three_steps_required_to_remove_two_C-4_methyl_groups_from_an_intermediate_in_ergosterol_biosynthesis" YGL002W ERP6 None secretory_pathway molecular_function_unknown mitochondrion* None None 7 494521 495171 YGL002W S000002970 "ORF,_Verified" "Protein_with_similarity_to_Emp24p_and_Erv25p,_member_of_the_p24_family_involved_in_ER_to_Golgi_transport;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YGL004C RPN14 None proteolysis endopeptidase_activity cytoplasm* None None 7 491960 490707 YGL004C S000002972 "ORF,_Uncharacterized" Putative_non-ATPase_subunit_of_the_19S_regulatory_particle_of_the_26S_proteasome;_localized_to_the_cytoplasm YGL005C COG7 COD5 intra-Golgi_transport molecular_function_unknown mitochondrion* None None 7 490551 489712 YGL005C S000002973 "ORF,_Verified" "Component_of_the_conserved_oligomeric_Golgi_complex_(Cog1p_through_Cog8p),_a_cytosolic_tethering_complex_that_functions_in_protein_trafficking_to_mediate_fusion_of_transport_vesicles_to_Golgi_compartments" YGL006W PMC1 None calcium_ion_homeostasis* calcium-transporting_ATPase_activity vacuolar_membrane_(sensu_Fungi) None None 7 485925 489446 YGL006W S000002974 "ORF,_Verified" Vacuolar_Ca2+_ATPase_involved_in_depleting_cytosol_of_Ca2+_ions;_prevents_growth_inhibition_by_activation_of_calcineurin_in_the_presence_of_elevated_concentrations_of_calcium;_similar_to_mammalian_PMCA1a YGL008C PMA1 KTI10 regulation_of_pH* "hydrogen-exporting_ATPase_activity,_phosphorylative_mechanism" plasma_membrane* G2/M None 7 482671 479915 YGL008C S000002976 "ORF,_Verified" "Plasma_membrane_H+-ATPase,_pumps_protons_out_of_the_cell;_major_regulator_of_cytoplasmic_pH_and_plasma_membrane_potential;_part_of_the_P2_subgroup_of_cation-transporting_ATPases" YGL009C LEU1 None leucine_biosynthesis 3-isopropylmalate_dehydratase_activity cytosol None None 7 478657 476318 YGL009C S000002977 "ORF,_Verified" "Isopropylmalate_isomerase,_catalyzes_the_second_step_in_the_leucine_biosynthesis_pathway" YGL010W None None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 7 475550 476074 YGL010W S000002978 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YGL010W_is_not_an_essential_gene YGL011C SCL1 PRC2 ubiquitin-dependent_protein_catabolism endopeptidase_activity mitochondrion* None None 7 475252 474494 YGL011C S000002979 "ORF,_Verified" Alpha_1_subunit_of_the_20S_proteasome_involved_in_the_degradation_of_ubiquitinated_substrates;_20S_proteasome_is_the_core_complex_of_the_26S_proteasome;_essential_for_growth;_detected_in_the_mitochondria YGL012W ERG4 None ergosterol_biosynthesis delta24(24-1)_sterol_reductase_activity endoplasmic_reticulum None None 7 472860 474281 YGL012W S000002980 "ORF,_Verified" "C-24(28)_sterol_reductase,_catalyzes_the_final_step_in_ergosterol_biosynthesis;_mutants_are_viable,_but_lack_ergosterol" YGL013C PDR1 TPE3|TPE1|TIL1|SMR2|NRA2|CYH3|BOR2|ANT1|AMY1 regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus None None 7 472303 469097 YGL013C S000002981 "ORF,_Verified" Zinc_cluster_protein_that_is_a_master_regulator_involved_in_recruiting_other_zinc_cluster_proteins_to_pleiotropic_drug_response_elements_(PDREs)_to_fine_tune_the_regulation_of_multidrug_resistance_genes YGL016W KAP122 PDR6 protein_import_into_nucleus* protein_carrier_activity cytoplasm* None None 7 461671 464916 YGL016W S000002984 "ORF,_Verified" "Karyopherin_beta,_responsible_for_import_of_the_Toa1p-Toa2p_complex_into_the_nucleus;_binds_to_nucleoporins_Nup1p_and_Nup2p;_may_play_a_role_in_regulation_of_pleiotropic_drug_resistance" YGL018C JAC1 None aerobic_respiration* chaperone_binding mitochondrion None None 7 459669 459115 YGL018C S000002986 "ORF,_Verified" "Specialized_J-protein_that_functions_with_Hsp70_in_Fe-S_cluster_biogenesis_in_mitochondria,_involved_in_iron_metabolism;_contains_a_J_domain_typical_to_J-type_chaperones;_localizes_to_the_mitochondrial_matrix" YGL019W CKB1 None protein_amino_acid_phosphorylation* protein_kinase_CK2_regulator_activity protein_kinase_CK2_complex None None 7 458161 458997 YGL019W S000002987 "ORF,_Verified" "Beta_regulatory_subunit_of_casein_kinase_2,_a_Ser/Thr_protein_kinase_with_roles_in_cell_growth_and_proliferation;_the_holoenzyme_also_contains_CKA1,_CKA2_and_CKB2,_the_many_substrates_include_transcription_factors_and_all_RNA_polymerases" YGL020C GET1 MDM39 mitochondrion_organization_and_biogenesis* molecular_function_unknown endoplasmic_reticulum* None None 7 457875 457168 YGL020C S000002988 "ORF,_Verified" Subunit_of_the_GET_complex;_required_for_the_retrieval_of_HDEL_proteins_from_the_Golgi_to_the_ER_in_an_ERD2_dependent_fashion_and_for_normal_mitochondrial_morphology_and_inheritance YGL022W STT3 None protein_amino_acid_N-linked_glycosylation dolichyl-diphosphooligosaccharide-protein_glycotransferase_activity oligosaccharyl_transferase_complex None None 7 452409 454565 YGL022W S000002990 "ORF,_Verified" "Subunit_of_the_oligosaccharyltransferase_complex_of_the_ER_lumen,_which_catalyzes_asparagine-linked_glycosylation_of_newly_synthesized_proteins;_forms_a_subcomplex_with_Ost3p_and_Ost4p_and_is_directly_involved_in_catalysis" YGL023C PIB2 None vesicle-mediated_transport phosphatidylinositol_binding mitochondrion* None None 7 452109 450202 YGL023C S000002991 "ORF,_Verified" "Protein_binding_phosphatidylinositol_3-phosphate,_involved_in_telomere-proximal_repression_of_gene_expression;_similar_to_Fab1_and_Vps27" YGL025C PGD1 MED3|HRS1 transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_mediator_activity mediator_complex None None 7 449962 448769 YGL025C S000002993 "ORF,_Verified" Subunit_of_the_RNA_polymerase_II_mediator_complex;_associates_with_core_polymerase_subunits_to_form_the_RNA_polymerase_II_holoenzyme;_essential_for_basal_and_activated_transcription;_direct_target_of_Cyc8p-Tup1p_transcriptional_corepressor YGL026C TRP5 None tryptophan_biosynthesis tryptophan_synthase_activity cytoplasm* None None 7 448540 446417 YGL026C S000002994 "ORF,_Verified" "Tryptophan_synthase_involved_in_tryptophan_biosynthesis,_regulated_by_the_general_control_system_of_amino_acid_biosynthesis" YGL028C SCW11 None "cytokinesis,_completion_of_separation" "glucan_1,3-beta-glucosidase_activity" cell_wall_(sensu_Fungi) G1 None 7 442914 441286 YGL028C S000002996 "ORF,_Verified" Cell_wall_protein_with_similarity_to_glucanases;_may_play_a_role_in_conjugation_during_mating_based_on_its_regulation_by_Ste12p YGL029W CGR1 None rRNA_processing* molecular_function_unknown nucleolus None None 7 440068 440430 YGL029W S000002997 "ORF,_Verified" Protein_involved_in_nucleolar_integrity_and_processing_of_the_pre-rRNA_for_the_60S_ribosome_subunit;_transcript_is_induced_in_response_to_cytotoxic_stress_but_not_genotoxic_stress YGL030W RPL30 None protein_biosynthesis* structural_constituent_of_ribosome cytoplasm* None None 7 439096 439643 YGL030W S000002998 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_rat_L30_ribosomal_protein;_involved_in_pre-rRNA_processing_in_the_nucleolus;_autoregulates_splicing_of_its_transcript" YGL031C RPL24A RPL30A protein_biosynthesis structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 7 437939 437472 YGL031C S000002999 "ORF,_Verified" "Ribosomal_protein_L30_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl24Bp_and_has_similarity_to_rat_L24_ribosomal_protein;_not_essential_for_translation_but_may_be_required_for_normal_translation_rate" YGL032C AGA2 None agglutination_during_conjugation_with_cellular_fusion cell_adhesion_molecule_binding cell_wall_(sensu_Fungi) M/G1 None 7 436838 436575 YGL032C S000003000 "ORF,_Verified" "Adhesion_subunit_of_a-agglutinin_of_a-cells,_C-terminal_sequence_acts_as_a_ligand_for_alpha-agglutinin_(Sag1p)_during_agglutination,_modified_with_O-linked_oligomannosyl_chains,_linked_to_anchorage_subunit_Aga1p_via_two_disulfide_bonds" YGL037C PNC1 None chromatin_silencing_at_telomere* nicotinamidase_activity cytoplasm* M/G1 None 7 427953 427303 YGL037C S000003005 "ORF,_Verified" "Nicotinamidase_that_converts_nicotinamide_to_nicotinic_acid_as_part_of_the_NAD(+)_salvage_pathway,_required_for_life_span_extension_by_calorie_restriction;_PNC1_expression_responds_to_all_known_stimuli_that_extend_replicative_life_span" YGL038C OCH1 LDB12|NGD29 protein_amino_acid_N-linked_glycosylation "alpha-1,6-mannosyltransferase_activity*" Golgi_cis_cisterna G1 None 7 426810 425368 YGL038C S000003006 "ORF,_Verified" "Mannosyltransferase_of_the_cis-Golgi_apparatus,_initiates_the_polymannose_outer_chain_elongation_of_N-linked_oligosaccharides_of_glycoproteins" YGL039W None None biological_process_unknown oxidoreductase_activity* cytoplasm None None 7 423967 425013 YGL039W S000003007 "ORF,_Verified" Oxidoreductase_shown_to_reduce_carbonyl_compounds_to_chiral_alcohols YGL040C HEM2 SLU1 heme_biosynthesis porphobilinogen_synthase_activity cytoplasm* None None 7 420561 419533 YGL040C S000003008 "ORF,_Verified" "Delta-aminolevulinate_dehydratase,_a_homo-octameric_enzyme,_catalyzes_the_conversion_of_delta-aminolevulinic_acid_to_porphobilinogen,_the_second_step_in_the_heme_biosynthetic_pathway;_localizes_to_both_the_cytoplasm_and_nucleus" YGL044C RNA15 None mRNA_polyadenylylation* RNA_binding* mRNA_cleavage_factor_complex None None 7 417040 416150 YGL044C S000003012 "ORF,_Verified" Cleavage_and_polyadenylation_factor_I_(CF_I)_component_involved_in_cleavage_and_polyadenylation_of_mRNA_3'_ends;_interacts_with_the_A-rich_polyadenylation_signal_in_complex_with_Rna14p_and_Hrp1p YGL045W RIM8 YGL046W|PAL3 meiosis* molecular_function_unknown cellular_component_unknown None None 7 414106 415734 YGL046W S000003013 "ORF,_Verified" "Protein_of_unknown_function,_involved_in_the_proteolytic_activation_of_Rim101p_in_response_to_alkaline_pH;_has_similarity_to_A._nidulans_PalF" YGL047W ALG13 None dolichol-linked_oligosaccharide_biosynthesis N-acetylglucosaminyldiphosphodolichol_N-acetylglucosaminyltransferase_activity* cytoplasm* None Up 7 411555 412163 YGL047W S000003015 "ORF,_Verified" "Catalytic_component_of_UDP-GlcNAc_transferase,_required_for_the_second_step_of_dolichyl-linked_oligosaccharide_synthesis;_anchored_to_the_ER_membrane_via_interaction_with_Alg14p;_similar_to_bacterial_and_human_glycosyltransferases" YGL048C RPT6 SUG1|SCB68|CRL3|CIM3 ubiquitin-dependent_protein_catabolism ATPase_activity* nucleus* None None 7 411289 410072 YGL048C S000003016 "ORF,_Verified" One_of_six_ATPases_of_the_19S_regulatory_particle_of_the_26S_proteasome_involved_in_the_degradation_of_ubiquitinated_substrates;_bound_by_ubiquitin-protein_ligases_Ubr1p_and_Ufd4p;_localized_mainly_to_the_nucleus_throughout_the_cell_cycle YGL050W TYW3 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 405779 406600 YGL050W S000003018 "ORF,_Verified" "tRNA_methyltransferase_required_for_synthesis_of_wybutosine,_a_modified_guanosine_found_at_the_3'-position_adjacent_to_the_anticodon_of_phenylalanine_tRNA_which_supports_reading_frame_maintenance_by_stabilizing_codon-anticodon_interactions" YGL051W MST27 None vesicle_organization_and_biogenesis protein_binding endoplasmic_reticulum* None None 7 403690 404394 YGL051W S000003019 "ORF,_Verified" "Putative_integral_membrane_protein,_involved_in_vesicle_formation;_forms_complex_with_Mst28p;_member_of_DUP240_gene_family;_binds_COPI_and_COPII_vesicles" YGL053W PRM8 None conjugation_with_cellular_fusion molecular_function_unknown endoplasmic_reticulum* None None 7 402592 403305 YGL053W S000003021 "ORF,_Verified" "Pheromone-regulated_protein_with_2_predicted_transmembrane_segments_and_an_FF_sequence,_a_motif_involved_in_COPII_binding;_forms_a_complex_with_Prp9p_in_the_ER;_member_of_DUP240_gene_family" YGL054C ERV14 None ER_to_Golgi_transport* molecular_function_unknown endoplasmic_reticulum_membrane* None None 7 401290 400874 YGL054C S000003022 "ORF,_Verified" "Protein_localized_to_COPII-coated_vesicles,_involved_in_vesicle_formation_and_incorporation_of_specific_secretory_cargo;_required_for_the_delivery_of_bud-site_selection_protein_Axl2p_to_cell_surface;_related_to_Drosophila_cornichon" YGL055W OLE1 MDM2 mitochondrion_inheritance* stearoyl-CoA_9-desaturase_activity endoplasmic_reticulum_membrane M/G1 Down 7 398631 400163 YGL055W S000003023 "ORF,_Verified" "Delta(9)_fatty_acid_desaturase,_required_for_monounsaturated_fatty_acid_synthesis_and_for_normal_distribution_of_mitochondria" YGL056C SDS23 None biological_process_unknown molecular_function_unknown cytoplasm* None None 7 397624 396041 YGL056C S000003024 "ORF,_Verified" "One_of_two_S._cerevisiae_homologs_(Sds23p_and_Sds24p)_of_the_Schizosaccharomyces_pombe_Sds23_protein,_which_genetic_studies_have_implicated_in_APC/cyclosome_regulation" YGL057C None None biological_process_unknown molecular_function_unknown mitochondrion None None 7 395835 394972 YGL057C S000003025 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_null_mutant_exhibits_a_growth_defect_on_a_non-fermentable_(respiratory)_carbon_source" YGL058W RAD6 PSO8|UBC2 DNA_repair* ubiquitin_conjugating_enzyme_activity cytoplasm* None None 7 393992 394510 YGL058W S000003026 "ORF,_Verified" "Ubiquitin-conjugating_enzyme_(E2),_involved_in_postreplication_repair_(with_Rad18p),_sporulation,_telomere_silencing,_and_ubiquitin-mediated_N-end_rule_protein_degradation_(with_Ubr1p)" YGL059W PKP2 None biological_process_unknown protein_kinase_activity mitochondrion None None 7 392228 393703 YGL059W S000003027 "ORF,_Verified" Mitochondrial_protein_kinase_that_negatively_regulates_activity_of_the_pyruvate_dehydrogenase_complex_by_phosphorylating_the_ser-133_residue_of_the_Pda1p_subunit;_acts_in_concert_with_kinase_Pkp1p_and_phosphatases_Ptc5p_and_Ptc6p YGL060W YBP2 None biological_process_unknown molecular_function_unknown cytoplasm G1 Up 7 390070 391995 YGL060W S000003028 "ORF,_Verified" Central_kinetochore_associated_protein_that_mediates_mitotic_progression;_interacts_with_several_central_kinetochore_proteins_and_the_centromeric_histone_Cse4p;_role_in_resistance_to_oxidative_stress;_similarity_to_Ybp1p_and_Slk19p YGL062W PYC1 None gluconeogenesis* pyruvate_carboxylase_activity cytosol None Up 7 385199 388735 YGL062W S000003030 "ORF,_Verified" "Pyruvate_carboxylase_isoform,_cytoplasmic_enzyme_that_converts_pyruvate_to_oxaloacetate;_highly_similar_to_isoform_Pyc2p_but_differentially_regulated;_mutations_in_the_human_homolog_are_associated_with_lactic_acidosis" YGL063W PUS2 None tRNA_modification tRNA-pseudouridine_synthase_activity cellular_component_unknown None None 7 383657 384769 YGL063W S000003031 "ORF,_Verified" "Mitochondrial_tRNA:pseudouridine_synthase;_acts_at_positions_27_and_28,_but_not_at_position_72;_efficiently_and_rapidly_targeted_to_mitochondria,_specifically_dedicated_to_mitochondrial_tRNA_modification" YGL064C MRH4 None ribosome_biogenesis RNA_helicase_activity mitochondrion None None 7 383211 381526 YGL064C S000003032 "ORF,_Verified" "Mitochondrial_ATP-dependent_RNA_helicase_of_the_DEAD-box_family,_plays_an_essential_role_in_mitochondrial_function" YGL066W SGF73 SCA7 histone_acetylation molecular_function_unknown SAGA_complex None None 7 377612 379585 YGL066W S000003034 "ORF,_Verified" Subunit_of_SAGA_histone_acetyltransferase_complex;_involved_in_formation_of_the_preinitiation_complex_assembly_at_promoters;_null_mutant_displays_defects_in_premeiotic_DNA_synthesis YGL067W NPY1 None NADH_metabolism NAD+_diphosphatase_activity cytoplasm* None None 7 376104 377258 YGL067W S000003035 "ORF,_Verified" "NADH_diphosphatase_(pyrophosphatase),_hydrolyzes_the_pyrophosphate_linkage_in_NADH_and_related_nucleotides;_localizes_to_peroxisomes" YGL068W MNP1 None aerobic_respiration* molecular_function_unknown* mitochondrion* None None 7 375090 375674 YGL068W S000003036 "ORF,_Verified" Protein_associated_with_the_mitochondrial_nucleoid;_putative_mitochondrial_ribosomal_protein_with_similarity_to_E._coli_L7/L12_ribosomal_protein;_required_for_normal_respiratory_growth YGL070C RPB9 SSU73|SHI1 transcription_from_RNA_polymerase_II_promoter DNA-directed_RNA_polymerase_activity "DNA-directed_RNA_polymerase_II,_core_complex" None None 7 374830 374462 YGL070C S000003038 "ORF,_Verified" RNA_polymerase_II_subunit_B12.6;_contacts_DNA;_mutations_affect_transcription_start_site;_involved_in_telomere_maintenance YGL071W AFT1 RCS1 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_factor_activity cytoplasm* None None 7 372015 374087 YGL071W S000003039 "ORF,_Verified" Transcription_factor_involved_in_iron_utilization_and_homeostasis;_binds_the_consensus_site_PyPuCACCCPu_and_activates_the_expression_of_target_genes_in_response_to_changes_in_iron_availability YGL073W HSF1 MAS3|EXA3 regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_factor_activity nucleus* None None 7 368756 371257 YGL073W S000003041 "ORF,_Verified" "Trimeric_heat_shock_transcription_factor,_activates_multiple_genes_in_response_to_stresses_that_include_hyperthermia;_recognizes_variable_heat_shock_elements_(HSEs)_consisting_of_inverted_NGAAN_repeats;_posttranslationally_regulated" YGL075C MPS2 MMC1 spindle_pole_body_duplication_in_nuclear_envelope* structural_constituent_of_cytoskeleton nuclear_envelope* None None 7 368091 366928 YGL075C S000003043 "ORF,_Verified" "Essential_membrane_protein_localized_at_the_nuclear_envelope_and_spindle_pole_body_(SPB),_required_for_insertion_of_the_newly_duplicated_SPB_into_the_nuclear_envelope;_potentially_phosphorylated_by_Cdc28p" YGL076C RPL7A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 7 365999 364338 YGL076C S000003044 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl7Bp_and_has_similarity_to_E._coli_L30_and_rat_L7_ribosomal_proteins;_contains_a_conserved_C-terminal_Nucleic_acid_Binding_Domain_(NDB2)" YGL077C HNM1 CTR1 choline_transport choline_transporter_activity plasma_membrane None None 7 363919 362228 YGL077C S000003045 "ORF,_Verified" Choline/ethanolamine_transporter;_involved_in_the_uptake_of_nitrogen_mustard_and_the_uptake_of_glycine_betaine_during_hypersaline_stress;_co-regulated_with_phospholipid_biosynthetic_genes_and_negatively_regulated_by_choline_and_myo-inositol YGL078C DBP3 None 35S_primary_transcript_processing* ATP-dependent_RNA_helicase_activity nucleolus None Down 7 361862 360291 YGL078C S000003046 "ORF,_Verified" Putative_ATP-dependent_RNA_helicase_of_the_DEAD-box_family_involved_in_ribosomal_biogenesis YGL079W None None biological_process_unknown molecular_function_unknown endosome None None 7 359447 360103 YGL079W S000003047 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_endosome;_identified_as_a_transcriptional_activator_in_a_high-throughput_yeast_one-hybrid_assay YGL080W None None biological_process_unknown molecular_function_unknown mitochondrion None None 7 358639 359031 YGL080W S000003048 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_highly_conserved_across_species_and_orthologous_to_human_gene_BRP44L;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YGL081W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 357380 358342 YGL081W S000003049 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_non-essential_gene;_interacts_genetically_with_CHS5,_a_gene_involved_in_chitin_biosynthesis" YGL082W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 7 355830 356975 YGL082W S000003050 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_predicted_prenylation/proteolysis_target_of_Afc1p_and_Rce1p;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus;_YGL082W_is_not_an_essential_gene YGL083W SCY1 None biological_process_unknown molecular_function_unknown clathrin-coated_vesicle None None 7 353061 355475 YGL083W S000003051 "ORF,_Verified" "Putative_kinase,_suppressor_of_GTPase_mutant,_similar_to_bovine_rhodopsin_kinase" YGL084C GUP1 None glycerol_transport* O-acyltransferase_activity endoplasmic_reticulum* None None 7 352301 350619 YGL084C S000003052 "ORF,_Verified" Plasma_membrane_protein_involved_in_remodeling_GPI_anchors;_member_of_the_MBOAT_family_of_putative_membrane-bound_O-acyltransferases;_proposed_to_be_involved_in_glycerol_transport YGL085W None None biological_process_unknown molecular_function_unknown mitochondrion None None 7 349619 350443 YGL085W S000003053 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_has_homology_to_Staphylococcus_aureus_nuclease;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_mitochondria_and_is_induced_in_response_to_the_DNA-damaging_agent_MMS" YGL086W MAD1 None mitotic_spindle_checkpoint* molecular_function_unknown nucleus* None None 7 347122 349371 YGL086W S000003054 "ORF,_Verified" Coiled-coil_protein_involved_in_the_spindle-assembly_checkpoint;_phosphorylated_by_Mps1p_upon_checkpoint_activation_which_leads_to_inhibition_of_the_activity_of_the_anaphase_promoting_complex;_forms_a_complex_with_Mad2p YGL087C MMS2 None protein_polyubiquitination* ubiquitin_conjugating_enzyme_activity cytoplasm* None None 7 346907 346409 YGL087C S000003055 "ORF,_Verified" "Protein_involved_in_error-free_postreplication_DNA_repair;_forms_a_heteromeric_complex_with_Ubc13p_that_has_a_ubiquitin-conjugating_activity;_cooperates_with_chromatin-associated_RING_finger_proteins,_Rad18p_and_Rad5p" YGL089C MF(ALPHA)2 None response_to_pheromone_during_conjugation_with_cellular_fusion mating_pheromone_activity extracellular_region G1 None 7 345156 344794 YGL089C S000003057 "ORF,_Verified" "Mating_pheromone_alpha-factor,_made_by_alpha_cells;_interacts_with_mating_type_a_cells_to_induce_cell_cycle_arrest_and_other_responses_leading_to_mating;_also_encoded_by_MF(ALPHA)1,_which_is_more_highly_expressed_than_MF(ALPHA)2" YGL090W LIF1 None double-strand_break_repair_via_nonhomologous_end-joining structural_molecule_activity nucleus M/G1 None 7 343322 344587 YGL090W S000003058 "ORF,_Verified" Component_of_the_DNA_ligase_IV_complex_that_mediates_nonhomologous_end_joining_in_DNA_double-strand_break_repair;_physically_interacts_with_Dnl4p_and_Nej1p;_homologous_to_mammalian_XRCC4_protein YGL092W NUP145 RAT10 mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 7 337909 341862 YGL092W S000003060 "ORF,_Verified" "Essential_nucleoporin,_catalyzes_its_own_cleavage_in_vivo_to_generate_a_C-terminal_fragment_that_assembles_into_the_Nup84p_subcomplex_of_the_nuclear_pore_complex,_and_an_N-terminal_fragment_of_unknown_function_that_is_homologous_to_Nup100p" YGL094C PAN2 None postreplication_repair* poly(A)-specific_ribonuclease_activity cytoplasm* None None 7 334468 331121 YGL094C S000003062 "ORF,_Verified" "Essential_subunit_of_the_Pan2p-Pan3p_poly(A)-ribonuclease_complex,_which_acts_to_control_poly(A)_tail_length_and_regulate_the_stoichiometry_and_activity_of_postreplication_repair_complexes" YGL095C VPS45 VPL28|STT10 protein_complex_assembly* unfolded_protein_binding cytosol* None Up 7 330610 328877 YGL095C S000003063 "ORF,_Verified" "Protein_of_the_Sec1p/Munc-18_family,_essential_for_vacuolar_protein_sorting;_required_for_the_function_of_Pep12p_and_the_early_endosome/late_Golgi_SNARE_Tlg2p;_essential_for_fusion_of_Golgi-derived_vesicles_with_the_prevacuolar_compartment" YGL096W TOS8 None G1/S-specific_transcription_in_mitotic_cell_cycle transcription_factor_activity nucleus None None 7 325334 326164 YGL096W S000003064 "ORF,_Verified" "Homeodomain-containing_transcription_factor;_SBF_regulated_target_gene_that_in_turn_regulates_expression_of_genes_involved_in_G1/S_phase_events_such_as_bud_site_selection,_bud_emergence_and_cell_cycle_progression;_similarity_to_Cup9p" YGL098W USE1 SLT1 ER_to_Golgi_transport* SNAP_receptor_activity endoplasmic_reticulum None None 7 317345 318082 YGL098W S000003066 "ORF,_Verified" "Essential_SNARE_protein_localized_to_the_ER,_involved_in_retrograde_traffic_from_the_Golgi_to_the_ER;_forms_a_complex_with_the_SNAREs_Sec22p,_Sec20p_and_Ufe1p" YGL099W LSG1 KRE35 sporulation_(sensu_Fungi)* GTPase_activity cytoplasm None None 7 314634 316556 YGL099W S000003067 "ORF,_Verified" Putative_GTPase_involved_in_60S_ribosomal_subunit_biogenesis;_required_for_the_release_of_Nmd3p_from_60S_subunits_in_the_cytoplasm YGL100W SEH1 None mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 7 313237 314286 YGL100W S000003068 "ORF,_Verified" "Nuclear_pore_protein_that_is_part_of_the_evolutionarily_conserved_Nup84p_complex_(Nup84p,_Nup85p,_Nup120p,_Nup145p,_and_Seh1p);_homologous_to_Sec13p" YGL101W None None biological_process_unknown molecular_function_unknown cytoplasm* S/G2 None 7 312196 312843 YGL101W S000003069 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene_with_similarity_to_YBR242W;_interacts_with_the_DNA_helicase_Hpr5p YGL103W RPL28 CYH2 protein_biosynthesis structural_constituent_of_ribosome* nucleus* None None 7 310970 311930 YGL103W S000003071 "ORF,_Verified" "Ribosomal_protein_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_E._coli_L15_and_rat_L27a_ribosomal_proteins;_may_have_peptidyl_transferase_activity;_can_mutate_to_cycloheximide_resistance" YGL104C VPS73 None protein_targeting_to_vacuole molecular_function_unknown mitochondrion None Up 7 310176 308716 YGL104C S000003072 "ORF,_Verified" Mitochondrial_protein;_mutation_affects_vacuolar_protein_sorting;_putative_transporter;_member_of_the_sugar_porter_family YGL106W MLC1 None endocytosis* microfilament_motor_activity actin_cap None None 7 306563 307012 YGL106W S000003074 "ORF,_Verified" "Essential_light_chain_for_Myo1p,_light_chain_for_Myo2p;_stabilizes_Myo2p_by_binding_to_the_neck_region;_interacts_with_Myo1p,_Iqg1p,_and_Myo2p_to_coordinate_formation_and_contraction_of_the_actomyosin_ring_with_targeted_membrane_deposition" YGL107C RMD9 None biological_process_unknown molecular_function_unknown mitochondrion None None 7 306276 304336 YGL107C S000003075 "ORF,_Verified" Mitochondrial_protein_required_for_respiratory_growth;_mutant_phenotype_and_genetic_interactions_suggest_a_role_in_delivering_mt_mRNAs_to_ribosomes;_located_on_matrix_face_of_the_inner_membrane_and_loosely_associated_with_mitoribosomes YGL110C CUE3 None biological_process_unknown molecular_function_unknown cytoplasm None None 7 303414 301540 YGL110C S000003078 "ORF,_Verified" "Protein_of_unknown_function;_has_a_CUE_domain_that_binds_ubiquitin,_which_may_facilitate_intramolecular_monoubiquitination" YGL111W NSA1 None ribosomal_large_subunit_biogenesis molecular_function_unknown nucleus* None None 7 299981 301372 YGL111W S000003079 "ORF,_Verified" "Constituent_of_66S_pre-ribosomal_particles,_involved_in_60S_ribosomal_subunit_biogenesis" YGL114W None None transport oligopeptide_transporter_activity membrane None Up 7 293463 295640 YGL114W S000003082 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_predicted_member_of_the_oligopeptide_transporter_(OPT)_family_of_membrane_transporters YGL115W SNF4 SCI1|CAT3 regulation_of_transcription_from_RNA_polymerase_II_promoter* protein_kinase_activator_activity cytoplasm* None None 7 292036 293004 YGL115W S000003083 "ORF,_Verified" "Activating_gamma_subunit_of_the_AMP-activated_Snf1p_kinase_complex_(contains_Snf1p_and_a_Sip1p/Sip2p/Gal83p_family_member);_activates_glucose-repressed_genes,_represses_glucose-induced_genes;_role_in_sporulation,_and_peroxisome_biogenesis" YGL116W CDC20 PAC5 mitotic_sister_chromatid_segregation* enzyme_activator_activity anaphase-promoting_complex G2/M None 7 289812 291644 YGL116W S000003084 "ORF,_Verified" "Cell-cycle_regulated_activator_of_anaphase-promoting_complex/cyclosome_(APC/C),_which_is_required_for_metaphase/anaphase_transition;_directs_ubiquitination_of_mitotic_cyclins,_Pds1p,_and_other_anaphase_inhibitors;_potential_Cdc28p_substrate" YGL117W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None Up 7 288518 289315 YGL117W S000003085 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YGL119W ABC1 COQ8 aerobic_respiration* molecular_function_unknown mitochondrion None None 7 284448 285953 YGL119W S000003087 "ORF,_Verified" "Protein_required_for_ubiquinone_(coenzyme_Q)_biosynthesis_and_for_respiratory_growth;_exhibits_genetic_interaction_with_COQ9,_suggesting_a_common_function;_similar_to_prokaryotic_proteins_involved_in_early_steps_of_ubiquinone_biosynthesis" YGL120C PRP43 JA1 U2-type_spliceosome_disassembly "RNA_splicing_factor_activity,_transesterification_mechanism*" mitochondrion* None None 7 283943 281640 YGL120C S000003088 "ORF,_Verified" "RNA_helicase_in_the_DEAH-box_family,_functions_in_both_RNA_polymerase_I_and_polymerase_II_transcript_metabolism,_involved_in_release_of_the_lariat-intron_from_the_spliceosome" YGL121C GPG1 None signal_transduction signal_transducer_activity cellular_component_unknown None Up 7 281163 280783 YGL121C S000003089 "ORF,_Verified" Proposed_gamma_subunit_of_the_heterotrimeric_G_protein_that_interacts_with_the_receptor_Grp1p;_involved_in_regulation_of_pseudohyphal_growth;_requires_Gpb1p_or_Gpb2p_to_interact_with_Gpa2p YGL122C NAB2 None mRNA_polyadenylylation* poly(A)_binding cytoplasm* None Up 7 280529 278952 YGL122C S000003090 "ORF,_Verified" Nuclear_polyadenylated_RNA-binding_protein_required_for_nuclear_mRNA_export_and_poly(A)_tail_length_control;_binds_nuclear_pore_protein_Mlp1p;_autoregulates_mRNA_levels;_related_to_human_hnRNPs;_nuclear_localization_sequence_binds_Kap104p YGL123W RPS2 SUP138|SUP44|SUP38|RPS4 protein_biosynthesis* structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota)* None None 7 277623 278387 YGL123W S000003091 "ORF,_Verified" "Protein_component_of_the_small_(40S)_subunit,_essential_for_control_of_translational_accuracy;_phosphorylation_by_C-terminal_domain_kinase_I_(CTDK-I)_enhances_translational_accuracy;_similar_to_E._coli_S5_and_rat_S2_ribosomal_proteins" YGL125W MET13 MRPL45|MET11 methionine_metabolism* structural_constituent_of_ribosome* cytoplasm* S None 7 272526 274328 YGL125W S000003093 "ORF,_Verified" "Major_isozyme_of_methylenetetrahydrofolate_reductase,_catalyzes_the_reduction_of_5,10-methylenetetrahydrofolate_to_5-methyltetrahydrofolate_in_the_methionine_biosynthesis_pathway" YGL126W SCS3 FIT2B phospholipid_metabolism molecular_function_unknown endoplasmic_reticulum None None 7 271003 272145 YGL126W S000003094 "ORF,_Verified" "Protein_required_for_inositol_prototrophy,_identified_as_an_ortholog_of_the_FIT_family_of_proteins_involved_in_triglyceride_droplet_biosynthesis;_disputed_role_in_the_synthesis_of_inositol_phospholipids_from_inositol" YGL128C CWC23 None biological_process_unknown molecular_function_unknown spliceosome_complex None None 7 270150 269299 YGL128C S000003096 "ORF,_Verified" "Component_of_a_complex_containing_Cef1p,_putatively_involved_in_pre-mRNA_splicing;_has_similarity_to_E._coli_DnaJ_and_other_DnaJ-like_proteins_and_to_S._pombe_Cwf23p" YGL129C RSM23 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 7 269194 267728 YGL129C S000003097 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_small_subunit,_has_similarity_to_mammalian_apoptosis_mediator_proteins;_null_mutation_prevents_induction_of_apoptosis_by_overproduction_of_metacaspase_Mca1p" YGL130W CEG1 None positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* mRNA_guanylyltransferase_activity nucleus None None 7 266150 267529 YGL130W S000003098 "ORF,_Verified" "Alpha_(guanylyltransferase)_subunit_of_the_mRNA_capping_enzyme,_a_heterodimer_(the_other_subunit_is_CET1,_an_RNA_5'-triphophatase)_involved_in_adding_the_5'_cap_to_mRNA;_the_mammalian_enzyme_is_a_single_bifunctional_polypeptide" YGL134W PCL10 None regulation_of_glycogen_biosynthesis* cyclin-dependent_protein_kinase_regulator_activity cyclin-dependent_protein_kinase_holoenzyme_complex None None 7 255668 256969 YGL134W S000003102 "ORF,_Verified" "Pho85p_cyclin;_recruits,_activates,_and_targets_Pho85p_cyclin-dependent_protein_kinase_to_its_substrate" YGL135W RPL1B SSM2 protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 7 254646 255299 YGL135W S000003103 "ORF,_Verified" "N-terminally_acetylated_protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl1Ap_and_has_similarity_to_E._coli_L1_and_rat_L10a_ribosomal_proteins;_rpl1a_rpl1b_double_null_mutation_is_lethal" YGL136C MRM2 None rRNA_modification rRNA_(uridine-2'-O-)-methyltransferase_activity mitochondrion None None 7 253864 252902 YGL136C S000003104 "ORF,_Verified" "Mitochondrial_2'_O-ribose_methyltransferase,_required_for_methylation_of_U(2791)_in_21S_rRNA;_MRM2_deletion_confers_thermosensitive_respiration_and_loss_of_mitochondrial_DNA;_has_similarity_to_Spb1p_and_Trm7p,_and_to_E._coli_FtsJ/RrmJ" YGL137W SEC27 None ER_to_Golgi_transport* molecular_function_unknown COPI_vesicle_coat None None 7 249874 252743 YGL137W S000003105 "ORF,_Verified" "Essential_beta'-coat_protein_of_the_COPI_coatomer,_involved_in_ER-to-Golgi_and_Golgi-to-ER_transport;_contains_WD40_domains_that_mediate_cargo_selective_interactions;_45%_sequence_identity_to_mammalian_beta'-COP" YGL138C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 249536 248499 YGL138C S000003106 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_has_no_significant_sequence_similarity_to_any_known_protein YGL139W FLC3 HUF3 biological_process_unknown molecular_function_unknown mitochondrion* None None 7 245721 248129 YGL139W S000003107 "ORF,_Verified" "Putative_FAD_transporter,_similar_to_Flc1p_and_Flc2p;_localized_to_the_ER" YGL140C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 245017 241358 YGL140C S000003108 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene;_contains_multiple_predicted_transmembrane_domains YGL141W HUL5 None protein_monoubiquitination* ubiquitin-protein_ligase_activity cytoplasm* None Up 7 238358 241090 YGL141W S000003109 "ORF,_Verified" "Ubiquitin-conjugating_enzyme_(E4),_elongates_polyubiquitin_chains_on_substrate_proteins;_works_in_opposition_to_Ubp6p_polyubiquitin-shortening_activity;_required_for_retrograde_transport_of_misfolded_proteins_into_cytoplasm_during_ERAD" YGL142C GPI10 None GPI_anchor_biosynthesis mannosyltransferase_activity integral_to_membrane None None 7 238124 236274 YGL142C S000003110 "ORF,_Verified" "Integral_membrane_protein_involved_in_glycosylphosphatidylinositol_(GPI)_anchor_synthesis;_putative_alpha_1,2_mannosyltransferase_required_for_addition_of_the_third_mannose_onto_the_GPI_core_structure;_human_PIG-Bp_is_a_functional_homolog" YGL143C MRF1 None protein_biosynthesis* translation_release_factor_activity mitochondrion None None 7 235963 234722 YGL143C S000003111 "ORF,_Verified" "Mitochondrial_translation_release_factor,_involved_in_stop_codon_recognition_and_hydrolysis_of_the_peptidyl-tRNA_bond_during_mitochondrial_translation;_lack_of_MRF1_causes_mitochondrial_genome_instability" YGL145W TIP20 TIP1 "retrograde_transport,_Golgi_to_ER" molecular_function_unknown endoplasmic_reticulum None None 7 230248 232353 YGL145W S000003113 "ORF,_Verified" "Peripheral_membrane_protein_required_for_fusion_of_COPI_vesicles_with_the_ER,_prohibits_back-fusion_of_COPII_vesicles_with_the_ER,_may_act_as_a_sensor_for_vesicles_at_the_ER_membrane;_interacts_with_Sec20p" YGL146C None None biological_process_unknown molecular_function_unknown membrane None None 7 229691 228756 YGL146C S000003114 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_contains_two_putative_transmembrane_spans,_shows_no_significant_homology_to_any_other_known_protein_sequence,_YGL146C_is_not_an_essential_gene" YGL147C RPL9A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 7 228334 227759 YGL147C S000003115 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl9Bp_and_has_similarity_to_E._coli_L6_and_rat_L9_ribosomal_proteins" YGL148W ARO2 None aromatic_amino_acid_family_biosynthesis chorismate_synthase_activity* cytoplasm None None 7 226404 227534 YGL148W S000003116 "ORF,_Verified" "Bifunctional_chorismate_synthase_and_flavin_reductase,_catalyzes_the_conversion_of_5-enolpyruvylshikimate_3-phosphate_(EPSP)_to_form_chorismate,_which_is_a_precursor_to_aromatic_amino_acids" YGL153W PEX14 None protein_targeting_to_peroxisome* protein_binding peroxisomal_membrane None None 7 216278 217303 YGL153W S000003121 "ORF,_Verified" "Peroxisomal_membrane_peroxin_that_is_a_central_component_of_the_peroxisomal_protein_import_machinery;_interacts_with_both_PTS1_(Pex5p)_and_PTS2_(Pex7p),_peroxisomal_matrix_protein_signal_recognition_factors_and_membrane_receptor_Pex13p" YGL154C LYS5 None lysine_biosynthesis_via_aminoadipic_acid* phosphopantetheinyltransferase_activity cytoplasm None None 7 216101 215283 YGL154C S000003122 "ORF,_Verified" Phosphopantetheinyl_transferase_involved_in_lysine_biosynthesis;_converts_inactive_apo-form_of_Lys2p_(alpha-aminoadipate_reductase)_into_catalytically_active_holo-form_by_posttranslational_addition_of_phosphopantetheine YGL155W CDC43 CAL1 establishment_of_cell_polarity_(sensu_Fungi)* signal_transducer_activity* intracellular* None None 7 214086 215216 YGL155W S000003123 "ORF,_Verified" "Beta_subunit_of_geranylgeranyltransferase_type_I,_catalyzes_geranylgeranylation_to_the_cysteine_residue_in_proteins_containing_a_C-terminal_CaaX_sequence_ending_in_Leu_or_Phe;_has_substrates_important_for_morphogenesis" YGL157W None None biological_process_unknown oxidoreductase_activity* cytoplasm* None None 7 209011 210054 YGL157W S000003125 "ORF,_Verified" "Oxidoreductase,_catalyzes_NADPH-dependent_reduction_of_the_bicyclic_diketone_bicyclo[2.2.2]octane-2,6-dione_(BCO2,6D)_to_the_chiral_ketoalcohol_(1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one_(BCO2one6ol)" YGL158W RCK1 None protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity cellular_component_unknown None None 7 207038 208576 YGL158W S000003126 "ORF,_Verified" Protein_kinase_involved_in_the_response_to_oxidative_stress;_identified_as_suppressor_of_S._pombe_cell_cycle_checkpoint_mutations YGL159W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 202727 203839 YGL159W S000003127 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_deletion_mutant_has_no_detectable_phenotype YGL160W None None biological_process_unknown "oxidoreductase_activity,_oxidizing_metal_ions" membrane None None 7 200567 202279 YGL160W S000003128 "ORF,_Verified" "Putative_protein_of_unknown_function;_similar_to_iron/copper_reductases_(FRE1-8),_possibly_involved_in_iron_homeostasis;_may_interact_with_ribosomes,_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation)" YGL162W SUT1 None regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_factor_activity* nucleus G2/M None 7 198144 199043 YGL162W S000003130 "ORF,_Verified" Transcription_factor_of_the_Zn[II]2Cys6_family_involved_in_sterol_uptake;_involved_in_induction_of_hypoxic_gene_expression YGL164C YRB30 None biological_process_unknown protein_binding* cytoplasm* None None 7 193306 191984 YGL164C S000003132 "ORF,_Verified" "RanGTP-binding_protein,_inhibits_RanGAP1_(Rna1p)-mediated_GTP_hydrolysis_of_RanGTP_(Gsp1p);_shares_similarity_to_proteins_in_other_fungi_but_not_in_higher_eukaryotes" YGL166W CUP2 ACE1 transcription_initiation_from_RNA_polymerase_II_promoter* ligand-regulated_transcription_factor_activity nucleus None None 7 191135 191812 YGL166W S000003134 "ORF,_Verified" Copper-binding_transcription_factor;_activates_transcription_of_the_metallothionein_genes_CUP1-1_and_CUP1-2_in_response_to_elevated_copper_concentrations YGL167C PMR1 SSC1|LDB1|BSD1 secretory_pathway* calcium-transporting_ATPase_activity* Golgi_apparatus None None 7 190474 187622 YGL167C S000003135 "ORF,_Verified" High_affinity_Ca2+/Mn2+_P-type_ATPase_required_for_Ca2+_and_Mn2+_transport_into_Golgi;_involved_in_Ca2+_dependent_protein_sorting_and_processing;_mutations_in_human_homolog_ATP2C1_cause_acantholytic_skin_condition_Hailey-Hailey_disease YGL168W HUR1 None DNA_replication molecular_function_unknown cellular_component_unknown None None 7 187470 187802 YGL168W S000003136 "ORF,_Verified" Protein_of_unknown_function;_reported_null_mutant_phenotype_of_hydroxyurea_sensitivity_may_be_due_to_effects_on_overlapping_PMR1_gene YGL169W SUA5 None aerobic_respiration molecular_function_unknown cytoplasm None None 7 186065 187345 YGL169W S000003137 "ORF,_Verified" Protein_required_for_respiratory_growth;_null_mutation_suppresses_the_Cyc1p_translation_defect_caused_by_the_presence_of_an_aberrant_ATG_codon_upstream_of_the_correct_start YGL170C SPO74 None sporulation_(sensu_Fungi) structural_molecule_activity spindle_pole_body None None 7 185400 184159 YGL170C S000003138 "ORF,_Verified" "Component_of_the_meiotic_outer_plaque_of_the_spindle_pole_body,_involved_in_modifying_the_meiotic_outer_plaque_that_is_required_prior_to_prospore_membrane_formation" YGL171W ROK1 None 35S_primary_transcript_processing ATPase_activity* nucleolus None None 7 182396 184090 YGL171W S000003139 "ORF,_Verified" ATP-dependent_RNA_helicase_of_the_DEAD_box_family;_required_for_18S_rRNA_synthesis YGL173C KEM1 XRN1|SKI1|SEP1|RAR5|DST2 35S_primary_transcript_processing* recombinase_activity* cytoplasm* None None 7 180119 175533 YGL173C S000003141 "ORF,_Verified" "Evolutionarily-conserved_5'-3'_exonuclease_component_of_cytoplasmic_processing_(P)_bodies_involved_in_mRNA_decay;_plays_a_role_in_microtubule-mediated_processes,_filamentous_growth,_ribosomal_RNA_maturation,_and_telomere_maintenance" YGL174W BUD13 CWC26 "nuclear_mRNA_splicing,_via_spliceosome*" molecular_function_unknown nucleus None None 7 174551 175351 YGL174W S000003142 "ORF,_Verified" "Subunit_of_the_RES_complex,_which_is_required_for_nuclear_pre-mRNA_retention_and_splicing;_involved_in_bud-site_selection;_diploid_mutants_display_a_unipolar_budding_pattern_instead_of_the_wild-type_bipolar_pattern" YGL175C SAE2 COM1 meiotic_DNA_double-strand_break_processing molecular_function_unknown cytoplasm* None None 7 174328 173291 YGL175C S000003143 "ORF,_Verified" Endonuclease_that_processes_hairpin_DNA_structures_with_the_MRX_complex;_involved_in_meiotic_and_mitotic_double-strand_break_repair;_phosphorylated_in_response_to_DNA_damage_and_required_for_normal_resistance_to_DNA-damaging_agents YGL176C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 173085 171421 YGL176C S000003144 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_deletion_mutant_is_viable_and_has_no_detectable_phenotype YGL178W MPT5 UTH4|PUF5|HTR1 cell_wall_organization_and_biogenesis* mRNA_binding cytoplasm None None 7 167358 170577 YGL178W S000003146 "ORF,_Verified" "Member_of_the_Puf_family_of_RNA-binding_proteins;_binds_to_mRNAs_encoding_chromatin_modifiers_and_spindle_pole_body_components;_involved_in_longevity,_maintenance_of_cell_wall_integrity,_and_sensitivity_to_and_recovery_from_pheromone_arrest" YGL179C TOS3 None glucose_metabolism protein_kinase_activity cytoplasm* None None 7 165097 163415 YGL179C S000003147 "ORF,_Verified" "Protein_kinase,_related_to_and_functionally_redundant_with_Elm1p_and_Sak1p_for_the_phosphorylation_and_activation_of_Snf1p;_functionally_orthologous_to_LKB1,_a_mammalian_kinase_associated_with_Peutz-Jeghers_cancer-susceptibility_syndrome" YGL184C STR3 None methionine_biosynthesis cystathionine_beta-lyase_activity peroxisome S None 7 156018 154621 YGL184C S000003152 "ORF,_Verified" "Cystathionine_beta-lyase,_converts_cystathionine_into_homocysteine" YGL187C COX4 None aerobic_respiration* cytochrome-c_oxidase_activity respiratory_chain_complex_IV_(sensu_Eukaryota) None None 7 150177 149710 YGL187C S000003155 "ORF,_Verified" "Subunit_IV_of_cytochrome_c_oxidase,_which_is_the_terminal_member_of_the_mitochondrial_inner_membrane_electron_transport_chain;_N-terminal_25_residues_of_precursor_are_cleaved_during_mitochondrial_import;_phosphorylated" YGL191W COX13 None aerobic_respiration enzyme_regulator_activity* respiratory_chain_complex_IV_(sensu_Eukaryota) None None 7 144814 145203 YGL191W S000003159 "ORF,_Verified" "Subunit_VIa_of_cytochrome_c_oxidase,_which_is_the_terminal_member_of_the_mitochondrial_inner_membrane_electron_transport_chain;_not_essential_for_cytochrome_c_oxidase_activity_but_may_modulate_activity_in_response_to_ATP" YGL192W IME4 SPO8 meiosis* mRNA_methyltransferase_activity cellular_component_unknown None None 7 142252 144054 YGL192W S000003160 "ORF,_Verified" Probable_mRNA_N6-adenosine_methyltransferase_that_is_required_for_IME1_transcript_accumulation_and_for_sporulation;_expression_is_induced_in_starved_MATa/MAT_alpha_diploid_cells YGL193C None None None None None None None 7 142233 141922 YGL193C S000003161 "ORF,_Uncharacterized" "Haploid-specific_gene_repressed_by_a1-alpha2,_turned_off_in_sir3_null_strains,_absence_enhances_the_sensitivity_of_rad52-327_cells_to_campothecin_almost_100-fold" YGL195W GCN1 None regulation_of_translational_elongation molecular_function_unknown mitochondrion* G1 None 7 131531 139549 YGL195W S000003163 "ORF,_Verified" "Positive_regulator_of_the_Gcn2p_kinase_activity,_forms_a_complex_with_Gcn20p;_proposed_to_stimulate_Gcn2p_activation_by_an_uncharged_tRNA" YGL198W YIP4 None vesicle-mediated_transport Rab_GTPase_binding membrane None None 7 123596 124303 YGL198W S000003166 "ORF,_Verified" "Protein_that_interacts_with_Rab_GTPases,_localized_to_late_Golgi_vesicles;_computational_analysis_of_large-scale_protein-protein_interaction_data_suggests_a_possible_role_in_vesicle-mediated_transport" YGL200C EMP24 BST2 ER_to_Golgi_transport* molecular_function_unknown endoplasmic_reticulum* G1 None 7 123310 122699 YGL200C S000003168 "ORF,_Verified" "Integral_membrane_component_of_endoplasmic_reticulum-derived_COPII-coated_vesicles,_which_function_in_ER_to_Golgi_transport" YGL201C MCM6 None DNA_replication_initiation* chromatin_binding* cytoplasm* G2/M None 7 120911 117858 YGL201C S000003169 "ORF,_Verified" Protein_involved_in_DNA_replication;_component_of_the_Mcm2-7_hexameric_complex_that_binds_chromatin_as_a_part_of_the_pre-replicative_complex YGL206C CHC1 SWA5 endocytosis* structural_molecule_activity clathrin_vesicle_coat None None 7 107508 102547 YGL206C S000003174 "ORF,_Verified" "Clathrin_heavy_chain,_subunit_of_the_major_coat_protein_involved_in_intracellular_protein_transport_and_endocytosis;_two_heavy_chains_form_the_clathrin_triskelion_structural_component;_the_light_chain_(CLC1)_is_thought_to_regulate_function" YGL208W SIP2 SPM2 protein_amino_acid_phosphorylation* AMP-activated_protein_kinase_activity cytoplasm* None None 7 97342 98589 YGL208W S000003176 "ORF,_Verified" One_of_three_beta_subunits_of_the_Snf1_serine/threonine_protein_kinase_complex_involved_in_the_response_to_glucose_starvation;_null_mutants_exhibit_accelerated_aging;_N-myristoylprotein_localized_to_the_cytoplasm_and_the_plasma_membrane YGL211W NCS6 TUC1|YGL210W-A biological_process_unknown molecular_function_unknown mitochondrion None None 7 92516 93595 YGL211W S000003179 "ORF,_Verified" "Protein_required_for_thiolation_of_the_uridine_at_the_wobble_position_of_Gln,_Lys,_and_Glu_tRNAs;_has_a_role_in_urmylation_and_in_invasive_and_pseudohyphal_growth;_inhibits_replication_of_Brome_mosaic_virus_in_S._cerevisiae" YGL216W KIP3 None mitotic_spindle_organization_and_biogenesis_in_nucleus* microtubule_motor_activity cytoplasmic_microtubule* S/G2 None 7 84884 87301 YGL216W S000003184 "ORF,_Verified" Kinesin-related_motor_protein_involved_in_mitotic_spindle_positioning YGL221C NIF3 None biological_process_unknown molecular_function_unknown cytoplasm* None None 7 82291 81425 YGL221C S000003189 "ORF,_Verified" "Protein_of_unknown_function,_similar_to_Listeria_monocytogenes_major_sigma_factor_(rpoD_gene_product);_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YGL222C EDC1 None deadenylylation-dependent_decapping mRNA_binding cytoplasm None None 7 81185 80658 YGL222C S000003190 "ORF,_Verified" "RNA-binding_protein,_activates_mRNA_decapping_directly_by_binding_to_the_mRNA_substrate_and_enhancing_the_activity_of_the_decapping_proteins_Dcp1p_and_Dcp2p" YGL225W VRG4 VIG4|LDB3|GOG5|VAN2 protein_amino_acid_N-linked_glycosylation* nucleotide-sugar_transporter_activity mitochondrion* G1 None 7 76893 77906 YGL225W S000003193 "ORF,_Verified" Golgi_GDP-mannose_transporter;_regulates_Golgi_function_and_glycosylation_in_Golgi YGL226W None None biological_process_unknown molecular_function_unknown mitochondrion None Up 7 73339 73710 YGL226W S000003195 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_mitochondrion;_YGL226W_is_synthetically_sick_with_cdc13-1 YGL229C SAP4 None G1/S_transition_of_mitotic_cell_cycle protein_serine/threonine_phosphatase_activity cytoplasm* None None 7 66959 64503 YGL229C S000003198 "ORF,_Verified" "Protein_required_for_function_of_the_Sit4p_protein_phosphatase,_member_of_a_family_of_similar_proteins_that_form_complexes_with_Sit4p,_including_Sap155p,_Sap185p,_and_Sap190p" YGL230C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 64215 63772 YGL230C S000003199 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene YGL231C None None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 7 63620 63048 YGL231C S000003200 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_endoplasmic_reticulum;_over-expression_confers_increased_resistence_to_hydrogen_peroxide;_human_ortholog_TMEM85_may_function_in_apoptosis YGL232W TAN1 None tRNA_modification RNA_binding cytoplasm* None None 7 62075 63002 YGL232W S000003201 "ORF,_Verified" "Putative_tRNA_acetyltransferase,_RNA-binding_protein_required_for_the_formation_of_the_modified_nucleoside_N(4)-acetylcytidine_in_serine_and_leucine_tRNAs_but_not_required_for_the_same_modification_in_18S_rRNA" YGL233W SEC15 None cytokinesis* protein_binding bud_tip* None None 7 59122 61854 YGL233W S000003202 "ORF,_Verified" "Essential_113kDa_subunit_of_the_exocyst_complex_(Sec3p,_Sec5p,_Sec6p,_Sec8p,_Sec10p,_Sec15p,_Exo70p,_and_Exo84p),_which_mediates_polarized_targeting_of_vesicles_to_active_sites_of_exocytosis;_Sec15p_associates_with_Sec4p_and_vesicles" YGL234W "ADE5,7" None de_novo'_IMP_biosynthesis* phosphoribosylamine-glycine_ligase_activity* cytoplasm None None 7 56482 58890 YGL234W S000003203 "ORF,_Verified" "Bifunctional_enzyme_of_the_'de_novo'_purine_nucleotide_biosynthetic_pathway,_contains_aminoimidazole_ribotide_synthetase_and_glycinamide_ribotide_synthetase_activities" YGL237C HAP2 None transcription* transcriptional_activator_activity nucleus* None None 7 53528 52731 YGL237C S000003206 "ORF,_Verified" "Subunit_of_the_heme-activated,_glucose-repressed_Hap2p/3p/4p/5p_CCAAT-binding_complex,_a_transcriptional_activator_and_global_regulator_of_respiratory_gene_expression;_contains_sequences_sufficient_for_both_complex_assembly_and_DNA_binding" YGL238W CSE1 KAP109 protein_export_from_nucleus importin-alpha_export_receptor_activity nuclear_envelope None None 7 49552 52434 YGL238W S000003207 "ORF,_Verified" "Nuclear_envelope_protein_that_mediates_the_nuclear_export_of_importin_alpha_(Srp1p),_homolog_of_metazoan_CAS_protein,_required_for_accurate_chromosome_segregation" YGL240W DOC1 APC10 mitotic_sister_chromatid_segregation* enzyme_regulator_activity mitochondrion* None None 7 48613 49365 YGL240W S000003209 "ORF,_Verified" "Processivity_factor_required_for_the_ubiquitination_activity_of_the_anaphase_promoting_complex_(APC),_mediates_the_activity_of_the_APC_by_contributing_to_substrate_recognition;_involved_in_cyclin_proteolysis" YGL242C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 45197 44652 YGL242C S000003211 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_deletion_mutant_is_viable YGL245W GUS1 GSN1 glutamyl-tRNA_aminoacylation glutamate-tRNA_ligase_activity cytoplasm* None None 7 39023 41149 YGL245W S000003214 "ORF,_Verified" "Glutamyl-tRNA_synthetase_(GluRS),_forms_a_complex_with_methionyl-tRNA_synthetase_(Mes1p)_and_Arc1p;_complex_formation_increases_the_catalytic_efficiency_of_both_tRNA_synthetases_and_ensures_their_correct_localization_to_the_cytoplasm" YGL248W PDE1 None cAMP-mediated_signaling cAMP-specific_phosphodiesterase_activity cellular_component_unknown None None 7 35653 36762 YGL248W S000003217 "ORF,_Verified" "Low-affinity_cyclic_AMP_phosphodiesterase,_controls_glucose_and_intracellular_acidification-induced_cAMP_signaling,_target_of_the_cAMP-protein_kinase_A_(PKA)_pathway;_glucose_induces_transcription_and_inhibits_translation" YGL250W RMR1 None biological_process_unknown molecular_function_unknown cytoplasm* None None 7 31910 32635 YGL250W S000003219 "ORF,_Verified" Protein_required_for_meiotic_recombination_and_gene_conversion;_null_mutant_displays_reduced_PIS1_expression_and_growth_defects_on_non-fermentable_carbon_sources_and_minimal_media;_GFP-fusion_protein_localizes_to_both_cytoplasm_and_nucleus YGL251C HFM1 MER3 meiosis* DNA_helicase_activity nucleus None None 7 31636 27921 YGL251C S000003220 "ORF,_Verified" Meiosis_specific_DNA_helicase_involved_in_the_conversion_of_double-stranded_breaks_to_later_recombination_intermediates_and_in_crossover_control;_catalyzes_the_unwinding_of_Holliday_junctions;_has_ssDNA_and_dsDNA_stimulated_ATPase_activity YGL253W HXK2 SCI2|HKB|HEX1 replicative_cell_aging* hexokinase_activity nucleus* None None 7 23935 25395 YGL253W S000003222 "ORF,_Verified" Hexokinase_isoenzyme_2_that_catalyzes_phosphorylation_of_glucose_in_the_cytosol;_predominant_hexokinase_during_growth_on_glucose;_functions_in_the_nucleus_to_repress_expression_of_HXK1_and_GLK1_and_to_induce_expression_of_its_own_gene YGL255W ZRT1 None high-affinity_zinc_ion_transport high_affinity_zinc_uptake_transporter_activity integral_to_plasma_membrane G2/M None 7 20978 22108 YGL255W S000003224 "ORF,_Verified" "High-affinity_zinc_transporter_of_the_plasma_membrane,_responsible_for_the_majority_of_zinc_uptake;_transcription_is_induced_under_low-zinc_conditions_by_the_Zap1p_transcription_factor" YGL256W ADH4 ZRG5|NRC465 fermentation "alcohol_dehydrogenase_activity,_zinc-dependent" mitochondrion None None 7 15159 16307 YGL256W S000003225 "ORF,_Verified" "Alcohol_dehydrogenase_isoenzyme_type_IV,_dimeric_enzyme_demonstrated_to_be_zinc-dependent_despite_sequence_similarity_to_iron-activated_alcohol_dehydrogenases;_transcription_is_induced_in_response_to_zinc_deficiency" YGL257C MNT2 None protein_amino_acid_O-linked_glycosylation "alpha-1,3-mannosyltransferase_activity" cellular_component_unknown None None 7 14157 12481 YGL257C S000003226 "ORF,_Verified" Mannosyltransferase_involved_in_adding_the_4th_and_5th_mannose_residues_of_O-linked_glycans YGL260W None None None None None None None 7 6860 7090 YGL260W S000003229 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_transcription_is_significantly_increased_in_a_NAP1_deletion_background;_deletion_mutant_has_increased_accumulation_of_nickel_and_selenium YGL261C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 6652 6290 YGL261C S000003230 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_mRNA_expression_appears_to_be_regulated_by_SUT1_and_UPC2 YGL263W COS12 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 2790 3932 YGL263W S000003232 "ORF,_Verified" "Protein_of_unknown_function,_member_of_the_DUP380_subfamily_of_conserved,_often_subtelomerically-encoded_proteins" YGR001C None None biological_process_unknown methyltransferase_activity cytoplasm None Up 7 498038 497137 YGR001C S000003233 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_methyltransferase_family_members;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_required_for_replication_of_Brome_mosaic_virus_in_S._cerevisiae YGR002C SWC4 GOD1|EAF2 chromatin_remodeling* DNA_binding nucleus* None Up 7 499910 498480 YGR002C S000003234 "ORF,_Verified" Component_of_the_Swr1p_complex_that_incorporates_Htz1p_into_chromatin;_component_of_the_NuA4_histone_acetyltransferase_complex YGR003W CUL3 CULB ubiquitin-dependent_protein_catabolism protein_binding* cytoplasm* None None 7 500136 502370 YGR003W S000003235 "ORF,_Verified" "Ubiquitin-protein_ligase,_member_of_the_cullin_family_with_similarity_to_Cdc53p_and_human_CUL3;_required_for_ubiquitin-dependent_degredation_of_the_RNA_Polymerase_II_subunit_RPO21" YGR004W PEX31 None peroxisome_organization_and_biogenesis molecular_function_unknown integral_to_peroxisomal_membrane None None 7 502942 504330 YGR004W S000003236 "ORF,_Verified" "Peroxisomal_integral_membrane_protein,_involved_in_negative_regulation_of_peroxisome_size;_partially_functionally_redundant_with_Pex30p_and_Pex32p;_probably_acts_at_a_step_downstream_of_steps_mediated_by_Pex28p_and_Pex29p" YGR005C TFG2 None transcription_initiation_from_RNA_polymerase_II_promoter general_RNA_polymerase_II_transcription_factor_activity transcription_factor_TFIIF_complex None None 7 505863 504661 YGR005C S000003237 "ORF,_Verified" TFIIF_(Transcription_Factor_II)_middle_subunit;_involved_in_both_transcription_initiation_and_elongation_of_RNA_polymerase_II;_homologous_to_human_RAP30 YGR006W PRP18 None "nuclear_mRNA_splicing,_via_spliceosome*" "RNA_splicing_factor_activity,_transesterification_mechanism*" U4/U6_x_U5_tri-snRNP_complex* None None 7 506074 506829 YGR006W S000003238 "ORF,_Verified" "Splicing_factor_involved_in_the_positioning_of_the_3'_splice_site_during_the_second_catalytic_step_of_splicing,_part_of_snRNP_U5,_interacts_with_Slu7p" YGR008C STF2 None ATP_synthesis_coupled_proton_transport* molecular_function_unknown proton-transporting_ATP_synthase_complex_(sensu_Eukaryota) None None 7 508368 508114 YGR008C S000003240 "ORF,_Verified" Protein_involved_in_regulation_of_the_mitochondrial_F1F0-ATP_synthase;_Stf1p_and_Stf2p_may_act_as_stabilizing_factors_that_enhance_inhibitory_action_of_the_Inh1p_protein YGR010W NMA2 None NAD_metabolism nicotinate-nucleotide_adenylyltransferase_activity nucleus None Up 7 511549 512736 YGR010W S000003242 "ORF,_Verified" "Nicotinic_acid_mononucleotide_adenylyltransferase,_involved_in_de_novo_and_salvage_synthesis_of_NAD(+)" YGR013W SNU71 None "nuclear_mRNA_splicing,_via_spliceosome" RNA_binding snRNP_U1 None None 7 514558 516420 YGR013W S000003245 "ORF,_Verified" "Component_of_U1_snRNP_required_for_mRNA_splicing_via_spliceosome;_yeast_specific,_no_metazoan_counterpart" YGR014W MSB2 None establishment_of_cell_polarity_(sensu_Fungi)* osmosensor_activity integral_to_plasma_membrane* G1 None 7 516947 520867 YGR014W S000003246 "ORF,_Verified" Mucin_family_member_involved_in_the_Cdc42p-_and_MAP_kinase-dependent_filamentous_growth_signaling_pathway;_also_functions_as_an_osmosensor_in_parallel_to_the_Sho1p-mediated_pathway;_potential_Cdc28p_substrate YGR015C None None biological_process_unknown molecular_function_unknown mitochondrion None None 7 522080 521094 YGR015C S000003247 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_mitochondrion YGR016W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 522265 522837 YGR016W S000003248 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YGR017W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 7 523791 524684 YGR017W S000003249 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_both_the_nucleus_and_the_cytoplasm YGR019W UGA1 None nitrogen_utilization 4-aminobutyrate_transaminase_activity intracellular None None 7 525233 526648 YGR019W S000003251 "ORF,_Verified" Gamma-aminobutyrate_(GABA)_transaminase_(4-aminobutyrate_aminotransferase)_involved_in_the_4-aminobutyrate_and_glutamate_degradation_pathways;_required_for_normal_oxidative_stress_tolerance_and_nitrogen_utilization YGR020C VMA7 None vacuolar_acidification "hydrogen-transporting_ATPase_activity,_rotational_mechanism" vacuolar_membrane_(sensu_Fungi)* None None 7 527333 526977 YGR020C S000003252 "ORF,_Verified" "Subunit_F_of_the_eight-subunit_V1_peripheral_membrane_domain_of_vacuolar_H+-ATPase_(V-ATPase),_an_electrogenic_proton_pump_found_throughout_the_endomembrane_system;_required_for_the_V1_domain_to_assemble_onto_the_vacuolar_membrane" YGR021W None None biological_process_unknown molecular_function_unknown mitochondrion None None 7 527636 528508 YGR021W S000003253 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YGR026W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 532989 533825 YGR026W S000003258 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cell_periphery YGR027C RPS25A RPS31A protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 7 534462 534136 YGR027C S000003259 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps25Bp_and_has_similarity_to_rat_S25_ribosomal_protein YGR027W-A None None None None None None None 7 536061 537383 YGR027W-A S000007405 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YGR027W-B None None None None None None None 7 536061 541329 YGR027W-B S000007406 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YGR028W MSP1 YTA4 protein_targeting_to_mitochondrion ATPase_activity mitochondrial_outer_membrane None None 7 542207 543295 YGR028W S000003260 "ORF,_Verified" Mitochondrial_protein_involved_in_sorting_of_proteins_in_the_mitochondria;_putative_membrane-spanning_ATPase YGR029W ERV1 None mitochondrion_organization_and_biogenesis* thiol_oxidase_activity mitochondrion* None None 7 543557 544209 YGR029W S000003261 "ORF,_Verified" "Flavin-linked_sulfhydryl_oxidase_of_the_mitochondrial_intermembrane_space_(IMS),_oxidizes_Mia40p_as_part_of_a_disulfide_relay_system_that_promotes_IMS_retention_of_imported_proteins;_ortholog_of_human_hepatopoietin_(ALR)" YGR030C POP6 None rRNA_processing* ribonuclease_P_activity* ribonuclease_MRP_complex* None None 7 546161 545685 YGR030C S000003262 "ORF,_Verified" "Subunit_of_both_RNase_MRP,_which_cleaves_pre-rRNA,_and_nuclear_RNase_P,_which_cleaves_tRNA_precursors_to_generate_mature_5'_ends" YGR032W GSC2 FKS2 cell_wall_organization_and_biogenesis* "1,3-beta-glucan_synthase_activity" prospore_membrane* None None 7 548268 553955 YGR032W S000003264 "ORF,_Verified" "Catalytic_subunit_of_1,3-beta-glucan_synthase,_involved_in_formation_of_the_inner_layer_of_the_spore_wall;_activity_positively_regulated_by_Rho1p_and_negatively_by_Smk1p;_has_similarity_to_an_alternate_catalytic_subunit,_Fks1p_(Gsc1p)" YGR033C TIM21 FMP17 protein_import_into_mitochondrial_matrix molecular_function_unknown mitochondrion* None None 7 554971 554252 YGR033C S000003265 "ORF,_Verified" Constituent_of_the_mitochondrial_inner_membrane_presequence_translocase_(TIM23_complex);_may_regulate_protein_import_by_binding_to_both_the_translocase_of_the_outer_membrane_(TOM)_and_presequence-associated_motor_(PAM)_complexes YGR034W RPL26B None protein_biosynthesis structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 7 555816 556676 YGR034W S000003266 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl26Ap_and_has_similarity_to_E._coli_L24_and_rat_L26_ribosomal_proteins;_binds_to_5.8S_rRNA" YGR035C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G2/M None 7 557426 557076 YGR035C S000003267 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_potential_Cdc28p_substrate;_transcription_is_activated_by_paralogous_transcription_factors_Yrm1p_and_Yrr1p_along_with_genes_involved_in_multidrug_resistance" YGR036C CAX4 CWH8 protein_amino_acid_N-linked_glycosylation* pyrophosphatase_activity integral_to_endoplasmic_reticulum_membrane None None 7 558872 558153 YGR036C S000003268 "ORF,_Verified" "Dolichyl_pyrophosphate_(Dol-P-P)_phosphatase_with_a_luminally_oriented_active_site_in_the_ER,_cleaves_the_anhydride_linkage_in_Dol-P-P,_required_for_Dol-P-P-linked_oligosaccharide_intermediate_synthesis_and_protein_N-glycosylation" YGR038C-A None None None None None None None 7 567471 566149 YGR038C-A S000007407 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YGR038C-B None None None None None None None 7 567471 562203 YGR038C-B S000007408 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YGR038W ORM1 None response_to_unfolded_protein molecular_function_unknown endoplasmic_reticulum None None 7 560686 561354 YGR038W S000003270 "ORF,_Verified" "Evolutionarily_conserved_protein_with_similarity_to_Orm2p,_required_for_resistance_to_agents_that_induce_the_unfolded_protein_response;_human_ortholog_is_located_in_the_endoplasmic_reticulum" YGR040W KSS1 None invasive_growth_(sensu_Saccharomyces)* MAP_kinase_activity nucleus None None 7 575402 576508 YGR040W S000003272 "ORF,_Verified" Mitogen-activated_protein_kinase_(MAPK)_involved_in_signal_transduction_pathways_that_control_filamentous_growth_and_pheromone_response;_the_KSS1_gene_is_nonfunctional_in_S288C_strains_and_functional_in_W303_strains YGR041W BUD9 None bud_site_selection molecular_function_unknown bud_neck G1 None 7 577491 579134 YGR041W S000003273 "ORF,_Verified" "Protein_involved_in_bud-site_selection;_diploid_mutants_display_a_unipolar_budding_pattern_instead_of_the_wild-type_bipolar_pattern,_and_bud_at_the_distal_pole" YGR042W None None biological_process_unknown molecular_function_unknown cytoplasm* G1 None 7 579480 580295 YGR042W S000003274 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_involved_in_maintenance_of_proper_telomere_length;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_both_the_cytoplasm_and_the_nucleus YGR044C RME1 CSP1 meiosis* specific_transcriptional_repressor_activity nucleus M/G1 None 7 583896 582994 YGR044C S000003276 "ORF,_Verified" Zinc_finger_protein_involved_in_control_of_meiosis;_prevents_meiosis_by_repressing_IME1_expression_and_promotes_mitosis_by_activating_CLN2_expression;_directly_repressed_by_a1-a2_regulator;_mediates_cell_type_control_of_sporulation YGR046W TAM41 MMP37 protein_import_into_mitochondrial_matrix molecular_function_unknown mitochondrion None None 7 584899 586056 YGR046W S000003278 "ORF,_Verified" Mitochondrial_protein_involved_in_protein_import_into_the_mitochondrial_matrix;_maintains_the_functional_integrity_of_the_TIM23_protein_translocator_complex;_viability_of_null_mutant_is_strain-dependent;_mRNA_is_targeted_to_the_bud YGR047C TFC4 PCF1 transcription_initiation_from_RNA_polymerase_III_promoter RNA_polymerase_III_transcription_factor_activity transcription_factor_TFIIIC_complex None None 7 589473 586396 YGR047C S000003279 "ORF,_Verified" One_of_six_subunits_of_the_RNA_polymerase_III_transcription_initiation_factor_complex_(TFIIIC);_part_of_the_TauA_domain_of_TFIIIC_that_binds_BoxA_DNA_promoter_sites_of_tRNA_and_similar_genes;_has_TPR_motifs;_human_homolog_is_TFIIIC-102 YGR048W UFD1 None ubiquitin-dependent_protein_catabolism* protein_binding endoplasmic_reticulum None Up 7 589830 590915 YGR048W S000003280 "ORF,_Verified" "Protein_that_interacts_with_Cdc48p_and_Npl4p,_involved_in_recognition_of_polyubiquitinated_proteins_and_their_presentation_to_the_26S_proteasome_for_degradation;_involved_in_transporting_proteins_from_the_ER_to_the_cytosol" YGR049W SCM4 None cell_cycle molecular_function_unknown mitochondrion None None 7 591318 591881 YGR049W S000003281 "ORF,_Verified" "Potential_regulatory_effector_of_CDC4_function,_suppresses_a_temperature-sensitive_allele_of_CDC4,_tripartite_protein_structure_in_which_a_charged_region_separates_two_uncharged_domains,_not_essential_for_mitosis_or_meiosis" YGR052W FMP48 None biological_process_unknown kinase_activity mitochondrion None None 7 593600 594709 YGR052W S000003284 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_induced_by_treatment_with_8-methoxypsoralen_and_UVA_irradiation" YGR054W None None translational_initiation translation_initiation_factor_activity cytosolic_small_ribosomal_subunit_(sensu_Eukaryota)* None None 7 596697 598625 YGR054W S000003286 "ORF,_Verified" "Eukaryotic_initiation_factor_(eIF)_2A;_associates_specifically_with_both_40S_subunits_and_80_S_ribosomes,_and_interacts_genetically_with_both_eIF5b_and_eIF4E;_homologous_to_mammalian_eIF2A" YGR055W MUP1 None sulfur_amino_acid_transport L-methionine_porter_activity integral_to_plasma_membrane G1 None 7 599421 601145 YGR055W S000003287 "ORF,_Verified" "High_affinity_methionine_permease,_integral_membrane_protein_with_13_putative_membrane-spanning_regions;_also_involved_in_cysteine_uptake" YGR057C LST7 None vesicle-mediated_transport* protein_transporter_activity vesicle_coat None None 7 605505 604777 YGR057C S000003289 "ORF,_Verified" Protein_possibly_involved_in_a_post-Golgi_secretory_pathway;_required_for_the_transport_of_nitrogen-regulated_amino_acid_permease_Gap1p_from_the_Golgi_to_the_cell_surface YGR060W ERG25 None ergosterol_biosynthesis C-4_methylsterol_oxidase_activity plasma_membrane* None None 7 610568 611497 YGR060W S000003292 "ORF,_Verified" "C-4_methyl_sterol_oxidase,_catalyzes_the_first_of_three_steps_required_to_remove_two_C-4_methyl_groups_from_an_intermediate_in_ergosterol_biosynthesis;_mutants_accumulate_the_sterol_intermediate_4,4-dimethylzymosterol" YGR061C ADE6 None de_novo'_IMP_biosynthesis* phosphoribosylformylglycinamidine_synthase_activity cytoplasm None None 7 615969 611893 YGR061C S000003293 "ORF,_Verified" "Formylglycinamidine-ribonucleotide_(FGAM)-synthetase,_catalyzes_a_step_in_the_'de_novo'_purine_nucleotide_biosynthetic_pathway" YGR062C COX18 OXA2 cytochrome_c_oxidase_complex_assembly protein_transporter_activity integral_to_membrane* None None 7 617282 616332 YGR062C S000003294 "ORF,_Verified" "Mitochondrial_integral_inner_membrane_protein_required_for_membrane_insertion_of_C-terminus_of_Cox2p;_interacts_genetically_and_physically_with_Mss2p_and_Pnt1p;_similar_to_S._cerevisiae_Oxa1,_N._crassa_Oxa2p,_and_E._coli_YidC" YGR063C SPT4 None "regulation_of_transcription,_DNA-dependent*" RNA_polymerase_II_transcription_elongation_factor_activity nucleus* None None 7 617828 617520 YGR063C S000003295 "ORF,_Verified" "Protein_that_forms_a_complex_with_Spt5p_and_mediates_both_activation_and_inhibition_of_transcription_elongation,_and_plays_a_role_in_pre-mRNA_processing;_in_addition,_Spt4p_is_involved_in_kinetochore_function_and_gene_silencing" YGR065C VHT1 None biotin_transport biotin_transporter_activity plasma_membrane G2/M None 7 619862 618081 YGR065C S000003297 "ORF,_Verified" High-affinity_plasma_membrane_H+-biotin_(vitamin_H)_symporter;_mutation_results_in_fatty_acid_auxotrophy;_12_transmembrane_domain_containing_major_facilitator_subfamily_member;_mRNA_levels_negatively_regulated_by_iron_deprivation_and_biotin YGR067C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 624790 622406 YGR067C S000003299 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_contains_a_zinc_finger_motif_similar_to_that_of_Adr1p YGR068C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 627088 625328 YGR068C S000003300 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YGR068C_is_not_an_essential_gene. YGR070W ROM1 SKC1 cell_wall_organization_and_biogenesis* signal_transducer_activity* intracellular None None 7 627810 631277 YGR070W S000003302 "ORF,_Verified" "GDP/GTP_exchange_protein_(GEP)_for_Rho1p;_mutations_are_synthetically_lethal_with_mutations_in_rom2,_which_also_encodes_a_GEP" YGR071C None None biological_process_unknown molecular_function_unknown nucleus None None 7 634067 631485 YGR071C S000003303 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_deletion_mutant_has_increased_glycogen_accumulation;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus YGR072W UPF3 SUA6 mRNA_catabolism* molecular_function_unknown cytoplasm* None None 7 634308 635471 YGR072W S000003304 "ORF,_Verified" "Component_of_the_nonsense-mediated_mRNA_decay_(NMD)_pathway,_along_with_Nam7p_and_Nmd2p;_involved_in_decay_of_mRNA_containing_nonsense_codons;_involved_in_telomere_maintenance" YGR074W SMD1 SPP92 "nuclear_mRNA_splicing,_via_spliceosome" "RNA_splicing_factor_activity,_transesterification_mechanism*" U4/U6_x_U5_tri-snRNP_complex* None None 7 635716 636156 YGR074W S000003306 "ORF,_Verified" "Core_Sm_protein_Sm_D1;_part_of_heteroheptameric_complex_(with_Smb1p,_Smd2p,_Smd3p,_Sme1p,_Smx3p,_and_Smx2p)_that_is_part_of_the_spliceosomal_U1,_U2,_U4,_and_U5_snRNPs;_homolog_of_human_Sm_D1" YGR075C PRP38 None "nuclear_mRNA_splicing,_via_spliceosome" "RNA_splicing_factor_activity,_transesterification_mechanism" U4/U6_x_U5_tri-snRNP_complex None None 7 636879 636151 YGR075C S000003307 "ORF,_Verified" "Unique_component_of_the_U4/U6.U5_tri-snRNP_particle,_required_for_conformational_changes_which_result_in_the_catalytic_activation_of_the_spliceosome;_dispensible_for_spliceosome_assembly" YGR076C MRPL25 YMR26 protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 7 637581 637108 YGR076C S000003308 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YGR077C PEX8 PAS6 peroxisome_organization_and_biogenesis* peroxisome_targeting_sequence_binding peroxisomal_membrane* None None 7 639517 637748 YGR077C S000003309 "ORF,_Verified" "Intraperoxisomal_organizer_of_the_peroxisomal_import_machinery,_tightly_associated_with_the_lumenal_face_of_the_peroxisomal_membrane,_essential_for_peroxisome_biogenesis,_binds_PTS1-signal_receptor_Pex5p" YGR078C PAC10 RKS2|PFD3|GIM2 tubulin_folding tubulin_binding cytoplasm* None None 7 640375 639776 YGR078C S000003310 "ORF,_Verified" "Part_of_the_heteromeric_co-chaperone_GimC/prefoldin_complex,_which_promotes_efficient_protein_folding" YGR079W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 640724 641836 YGR079W S000003311 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YGR079W_is_not_an_essential_gene YGR080W TWF1 None bipolar_bud_site_selection* actin_monomer_binding actin_cortical_patch None Up 7 642014 643012 YGR080W S000003312 "ORF,_Verified" "Twinfilin,_highly_conserved_actin_monomer-sequestering_protein_involved_in_regulation_of_the_cortical_actin_cytoskeleton,_composed_of_two_cofilin-like_regions,_localizes_actin_monomers_to_sites_of_rapid_filament_assembly" YGR082W TOM20 MOM19|MAS20 protein_import_into_mitochondrial_matrix protein_transporter_activity mitochondrial_outer_membrane_translocase_complex None None 7 644048 644599 YGR082W S000003314 "ORF,_Verified" Component_of_the_TOM_(translocase_of_outer_membrane)_complex_responsible_for_recognition_and_initial_import_steps_for_all_mitochondrially_directed_proteins;_acts_as_a_receptor_for_incoming_precursor_proteins YGR083C GCD2 GCD12 translational_initiation translation_initiation_factor_activity* ribosome* None None 7 646819 644864 YGR083C S000003315 "ORF,_Verified" "Delta_subunit_of_the_translation_initiation_factor_eIF2B,_the_guanine-nucleotide_exchange_factor_for_eIF2;_activity_subsequently_regulated_by_phosphorylated_eIF2;_first_identified_as_a_negative_regulator_of_GCN4_expression" YGR084C MRP13 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 7 648146 647127 YGR084C S000003316 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YGR085C RPL11B None protein_biosynthesis* structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 7 648911 648387 YGR085C S000003317 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl11Ap;_involved_in_ribosomal_assembly;_depletion_causes_degradation_of_proteins_and_RNA_of_the_60S_subunit;_has_similarity_to_E._coli_L5_and_rat_L11" YGR086C PIL1 None response_to_heat protein_kinase_inhibitor_activity cytoplasm* M/G1 None 7 650621 649602 YGR086C S000003318 "ORF,_Verified" "Primary_component_of_eisosomes,_which_are_large_immobile_cell_cortex_structures_associated_with_endocytosis;_null_mutants_show_activation_of_Pkc1p/Ypk1p_stress_resistance_pathways;_detected_in_phosphorylated_state_in_mitochondria" YGR087C PDC6 None ethanol_metabolism pyruvate_decarboxylase_activity cytoplasm None None 7 652985 651294 YGR087C S000003319 "ORF,_Verified" "Minor_isoform_of_pyruvate_decarboxylase,_decarboxylates_pyruvate_to_acetaldehyde,_involved_in_amino_acid_catabolism;_transcription_is_glucose-_and_ethanol-dependent,_and_is_strongly_induced_during_sulfur_limitation" YGR088W CTT1 SPS101 response_to_stress catalase_activity cytoplasm None None 7 654638 656326 YGR088W S000003320 "ORF,_Verified" "Cytosolic_catalase_T,_has_a_role_in_protection_from_oxidative_damage_by_hydrogen_peroxide" YGR089W NNF2 None chromosome_segregation molecular_function_unknown membrane_fraction None None 7 656964 659774 YGR089W S000003321 "ORF,_Verified" "Protein_that_exhibits_physical_and_genetic_interactions_with_Rpb8p,_which_is_a_subunit_of_RNA_polymerases_I,_II,_and_III;_computational_analysis_of_large-scale_protein-protein_interaction_data_suggests_a_role_in_chromosome_segregation" YGR090W UTP22 None 35S_primary_transcript_processing snoRNA_binding nucleus* None None 7 662362 666075 YGR090W S000003322 "ORF,_Verified" "Possible_U3_snoRNP_protein_involved_in_maturation_of_pre-18S_rRNA,_based_on_computational_analysis_of_large-scale_protein-protein_interaction_data" YGR091W PRP31 None "nuclear_mRNA_splicing,_via_spliceosome" "RNA_splicing_factor_activity,_transesterification_mechanism" mitochondrion* None None 7 666345 667829 YGR091W S000003323 "ORF,_Verified" "Splicing_factor,_component_of_the_U4/U6-U5_snRNP_complex" YGR092W DBF2 None protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity bud_neck* G2/M None 7 668193 669911 YGR092W S000003324 "ORF,_Verified" Ser/Thr_kinase_involved_in_transcription_and_stress_response;_functions_as_part_of_a_network_of_genes_in_exit_from_mitosis;_localization_is_cell_cycle_regulated;_activated_by_Cdc15p_during_the_exit_from_mitosis YGR093W None None biological_process_unknown molecular_function_unknown nucleus None None 7 670392 671915 YGR093W S000003325 "ORF,_Uncharacterized" Putative_debranching_enzyme_associated_ribonuclease;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus YGR094W VAS1 None valyl-tRNA_aminoacylation valine-tRNA_ligase_activity cytoplasm* None None 7 672190 675504 YGR094W S000003326 "ORF,_Verified" Mitochondrial_and_cytoplasmic_valyl-tRNA_synthetase YGR095C RRP46 None 35S_primary_transcript_processing* 3'-5'-exoribonuclease_activity nuclear_exosome_(RNase_complex)* None None 7 676346 675675 YGR095C S000003327 "ORF,_Verified" Protein_involved_in_rRNA_processing;_component_of_the_exosome_3->5_exonuclease_complex YGR096W TPC1 None transport transporter_activity mitochondrial_inner_membrane* None None 7 676625 677569 YGR096W S000003328 "ORF,_Verified" Mitochondrial_membrane_transporter_that_mediates_uptake_of_the_essential_cofactor_thiamine_pyrophosphate_(ThPP)_into_mitochondria;_expression_appears_to_be_regulated_by_carbon_source;_member_of_the_mitochondrial_carrier_family YGR097W ASK10 None response_to_oxidative_stress* transcription_regulator_activity cytoplasm* None None 7 678699 682139 YGR097W S000003329 "ORF,_Verified" "Component_of_the_RNA_polymerase_II_holoenzyme,_phosphorylated_in_response_to_oxidative_stress;_has_a_role_in_destruction_of_Ssn8p,_which_relieves_repression_of_stress-response_genes" YGR099W TEL2 None telomerase-dependent_telomere_maintenance telomeric_DNA_binding nuclear_telomere_cap_complex S None 7 687903 689969 YGR099W S000003331 "ORF,_Verified" "Essential_DNA-binding_protein_specific_to_single-stranded_yeast_telomeric_DNA_repeats,_required_for_telomere_length_regulation_and_telomere_position_effect" YGR100W MDR1 GYP2|MIC1 biological_process_unknown Rab_GTPase_activator_activity cytoplasm* None None 7 690249 693101 YGR100W S000003332 "ORF,_Verified" "Cytoplasmic_GTPase-activating_protein_for_Ypt/Rab_transport_GTPases_Ypt6p,_Ypt31p_and_Sec4p;_involved_in_recycling_of_internalized_proteins_and_regulation_of_Golgi_secretory_function" YGR102C None None biological_process_unknown molecular_function_unknown mitochondrion None None 7 695139 694588 YGR102C S000003334 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_transposon_insertion_mutant_is_salt_sensitive_and_deletion_mutant_has_growth_defects;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YGR103W NOP7 YPH1 processing_of_20S_pre-rRNA* molecular_function_unknown nucleus* None None 7 695421 697238 YGR103W S000003335 "ORF,_Verified" Nucleolar_protein_involved_in_rRNA_processing_and_60S_ribosomal_subunit_biogenesis;_constituent_of_several_different_pre-ribosomal_particles;_required_for_exit_from_G0_and_the_initiation_of_cell_proliferation YGR104C SRB5 MED18 transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_mediator_activity mediator_complex None None 7 698372 697449 YGR104C S000003336 "ORF,_Verified" Subunit_of_the_RNA_polymerase_II_mediator_complex;_associates_with_core_polymerase_subunits_to_form_the_RNA_polymerase_II_holoenzyme;_essential_for_transcriptional_regulation;_involved_in_telomere_maintenance YGR105W VMA21 None protein_complex_assembly molecular_function_unknown endoplasmic_reticulum* None None 7 698603 698836 YGR105W S000003337 "ORF,_Verified" "Integral_membrane_protein_that_is_required_for_vacuolar_H+-ATPase_(V-ATPase)_function,_although_not_an_actual_component_of_the_V-ATPase_complex;_functions_in_the_assembly_of_the_V-ATPase;_localized_to_the_yeast_endoplasmic_reticulum_(ER)" YGR106C None None biological_process_unknown molecular_function_unknown vacuolar_membrane_(sensu_Fungi) None None 7 699790 698993 YGR106C S000003338 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuolar_memebrane YGR108W CLB1 SCB1 G2/M_transition_of_mitotic_cell_cycle* cyclin-dependent_protein_kinase_regulator_activity cytoplasm* G2/M None 7 703640 705055 YGR108W S000003340 "ORF,_Verified" "B-type_cyclin_involved_in_cell_cycle_progression;_activates_Cdc28p_to_promote_the_transition_from_G2_to_M_phase;_accumulates_during_G2_and_M,_then_targeted_via_a_destruction_box_motif_for_ubiquitin-mediated_degradation_by_the_proteasome" YGR109C CLB6 None G1/S_transition_of_mitotic_cell_cycle* cyclin-dependent_protein_kinase_regulator_activity cellular_component_unknown G1 None 7 706505 705363 YGR109C S000003341 "ORF,_Verified" B-type_cyclin_involved_in_DNA_replication_during_S_phase;_activates_Cdc28p_to_promote_initiation_of_DNA_synthesis;_functions_in_formation_of_mitotic_spindles_along_with_Clb3p_and_Clb4p;_most_abundant_during_late_G1 YGR109W-A None None None None None None None 7 707614 708486 YGR109W-A S000007346 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YGR109W-B None None None None None None None 7 707614 712258 YGR109W-B S000007347 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YGR111W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 7 715832 717034 YGR111W S000003343 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_both_the_cytoplasm_and_the_nucleus YGR112W SHY1 None aerobic_respiration unfolded_protein_binding integral_to_membrane* None None 7 717362 718531 YGR112W S000003344 "ORF,_Verified" Mitochondrial_inner_membrane_protein_required_for_assembly_of_cytochrome_c_oxidase_(complex_IV);_associates_with_complex_IV_assembly_intermediates_and_complex_III/complex_IV_supercomplexes;_similar_to_human_SURF1_involved_in_Leigh_Syndrome YGR113W DAM1 None mitotic_spindle_organization_and_biogenesis_in_nucleus* structural_constituent_of_cytoskeleton condensed_nuclear_chromosome_kinetochore* S None 7 718897 719928 YGR113W S000003345 "ORF,_Verified" "Essential_subunit_of_the_Dam1_complex_(aka_DASH_complex),_couples_kinetochores_to_the_force_produced_by_MT_depolymerization_thereby_aiding_in_chromosome_segregation;_Ipl1p_target_for_regulating_kinetochore-MT_attachments" YGR116W SPT6 SSN20|CRE2 "regulation_of_transcription,_DNA-dependent*" RNA_polymerase_II_transcription_elongation_factor_activity nucleus* None None 7 720413 724768 YGR116W S000003348 "ORF,_Verified" Transcription_elongation_factor_required_for_the_maintenance_of_chromatin_structure_during_transcription_in_order_to_inhibit_transcription_from_promoters_within_the_coding_region YGR117C None None biological_process_unknown molecular_function_unknown cytoplasm None None 7 726483 725053 YGR117C S000003349 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YGR118W RPS23A None protein_biosynthesis* structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 7 726978 727735 YGR118W S000003350 "ORF,_Verified" "Ribosomal_protein_28_(rp28)_of_the_small_(40S)_ribosomal_subunit,_required_for_translational_accuracy;_nearly_identical_to_Rps23Bp_and_similar_to_E._coli_S12_and_rat_S23_ribosomal_proteins;_deletion_of_both_RPS23A_and_RPS23B_is_lethal" YGR119C NUP57 None mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 7 729676 728051 YGR119C S000003351 "ORF,_Verified" "Nucleoporin,_essential_subunit_of_the_nuclear_pore_complex_(NPC),_functions_as_the_organizing_center_of_an_NPC_subcomplex_containing_Nsp1p,_Nup49p,_Nup57p,_and_Nic96p" YGR121C MEP1 AMT1 ammonium_transport ammonium_transporter_activity plasma_membrane None None 7 732932 731454 YGR121C S000003353 "ORF,_Verified" Ammonium_permease;_belongs_to_a_ubiquitous_family_of_cytoplasmic_membrane_proteins_that_transport_only_ammonium_(NH4+);_expression_is_under_the_nitrogen_catabolite_repression_regulation YGR122W None None biological_process_unknown molecular_function_unknown cytoplasm None None 7 733940 735148 YGR122W S000003354 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_deletion_mutants_do_not_properly_process_Rim101p_and_have_decreased_resistance_to_rapamycin;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YGR123C PPT1 None protein_amino_acid_dephosphorylation protein_serine/threonine_phosphatase_activity cytoplasm* None None 7 738208 736667 YGR123C S000003355 "ORF,_Verified" Protein_serine/threonine_phosphatase_with_similarity_to_human_phosphatase_PP5;_present_in_both_the_nucleus_and_cytoplasm;_expressed_during_logarithmic_growth;_computational_analyses_suggest_roles_in_phosphate_metabolism_and_rRNA_processing YGR124W ASN2 None asparagine_biosynthesis asparagine_synthase_(glutamine-hydrolyzing)_activity cytoplasm S/G2 Up 7 739949 741667 YGR124W S000003356 "ORF,_Verified" "Asparagine_synthetase,_isozyme_of_Asn1p;_catalyzes_the_synthesis_of_L-asparagine_from_L-aspartate_in_the_asparagine_biosynthetic_pathway" YGR125W None None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) None None 7 742330 745440 YGR125W S000003357 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_deletion_mutant_has_decreased_rapamycin_resistance_but_normal_wormannin_resistance;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuole YGR126W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 7 745840 746532 YGR126W S000003358 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_both_the_cytoplasm_and_the_nucleus_and_is_induced_in_response_to_the_DNA-damaging_agent_MMS YGR127W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 746803 747741 YGR127W S000003359 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_expression_is_regulated_by_Msn2p/Msn4p,_indicating_a_possible_role_in_stress_response" YGR129W SYF2 NTC31 "nuclear_mRNA_splicing,_via_spliceosome*" "RNA_splicing_factor_activity,_transesterification_mechanism" spliceosome_complex None None 7 750405 751052 YGR129W S000003361 "ORF,_Verified" Component_of_the_spliceosome_complex_involved_in_pre-mRNA_splicing;_involved_in_regulation_of_cell_cycle_progression YGR130C None None biological_process_unknown molecular_function_unknown cytoplasm None Up 7 753849 751399 YGR130C S000003362 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_specifically_phosphorylated_in_vitro_by_mammalian_diphosphoinositol_pentakisphosphate_(IP7) YGR131W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 754731 755255 YGR131W S000003363 "ORF,_Uncharacterized" "Protein_of_unknown_function;_expression_induced_in_response_to_ketoconazole;_promoter_region_contains_a_sterol_regulatory_element_motif,_which_has_been_identified_as_a_Upc2p-binding_site" YGR132C PHB1 None protein_folding* molecular_function_unknown mitochondrion* None None 7 756457 755594 YGR132C S000003364 "ORF,_Verified" "Subunit_of_the_prohibitin_complex_(Phb1p-Phb2p),_a_1.2_MDa_ring-shaped_inner_mitochondrial_membrane_chaperone_that_stabilizes_newly_synthesized_proteins;_determinant_of_replicative_life_span;_involved_in_mitochondrial_segregation" YGR133W PEX4 UBC10|PAS2 peroxisome_organization_and_biogenesis* ubiquitin_conjugating_enzyme_activity peroxisome None None 7 756901 757452 YGR133W S000003365 "ORF,_Verified" Peroxisomal_ubiquitin_conjugating_enzyme_required_for_peroxisomal_matrix_protein_import_and_peroxisome_biogenesis YGR134W CAF130 None regulation_of_transcription_from_RNA_polymerase_II_promoter molecular_function_unknown CCR4-NOT_complex None None 7 757775 761143 YGR134W S000003366 "ORF,_Verified" "Part_of_the_evolutionarily-conserved_CCR4-NOT_transcriptional_regulatory_complex_involved_in_controlling_mRNA_initiation,_elongation,_and_degradation" YGR135W PRE9 None ubiquitin-dependent_protein_catabolism* endopeptidase_activity "proteasome_core_complex,_alpha-subunit_complex_(sensu_Eukaryota)" None None 7 761397 762173 YGR135W S000003367 "ORF,_Verified" "Alpha_3_subunit_of_the_20S_proteasome,_the_only_nonessential_20S_subunit;_may_be_replaced_by_the_alpha_4_subunit_(Pre6p)_under_stress_conditions_to_create_a_more_active_proteasomal_isoform" YGR136W LSB1 None biological_process_unknown molecular_function_unknown cytoplasm* None None 7 762433 763158 YGR136W S000003368 "ORF,_Verified" "Protein_containing_an_N-terminal_SH3_domain;_binds_Las17p,_which_is_a_homolog_of_human_Wiskott-Aldrich_Syndrome_protein_involved_in_actin_patch_assembly_and_actin_polymerization" YGR138C TPO2 None polyamine_transport spermine_transporter_activity plasma_membrane* S/G2 None 7 765611 763767 YGR138C S000003370 "ORF,_Verified" Polyamine_transport_protein_specific_for_spermine;_localizes_to_the_plasma_membrane;_transcription_of_TPO2_is_regulated_by_Haa1p;_member_of_the_major_facilitator_superfamily YGR140W CBF2 CSL5|NDC10|CTF14|CEP2|CBF3A chromosome_segregation DNA_bending_activity* condensed_nuclear_chromosome_kinetochore* G1 None 7 767434 770304 YGR140W S000003372 "ORF,_Verified" "Essential_kinetochore_protein,_component_of_the_CBF3_multisubunit_complex_that_binds_to_the_CDEIII_region_of_the_centromere;_Cbf2p_also_binds_to_the_CDEII_region_possibly_forming_a_different_multimeric_complex,_ubiquitinated_in_vivo" YGR141W VPS62 None protein_targeting_to_vacuole molecular_function_unknown cellular_component_unknown None Up 7 770574 771977 YGR141W S000003373 "ORF,_Verified" Vacuolar_protein_sorting_(VPS)_protein_required_for_cytoplasm_to_vacuole_targeting_of_proteins YGR142W BTN2 None intracellular_protein_transport* molecular_function_unknown cytosol None None 7 772459 773691 YGR142W S000003374 "ORF,_Verified" "v-SNARE_binding_protein_that_facilitates_specific_protein_retrieval_from_a_late_endosome_to_the_Golgi;_modulates_arginine_uptake,_possible_role_in_mediating_pH_homeostasis_between_the_vacuole_and_plasma_membrane_H(+)-ATPase" YGR143W SKN1 None cell_wall_organization_and_biogenesis* glucosidase_activity integral_to_membrane G2/M None 7 775198 777513 YGR143W S000003375 "ORF,_Verified" Protein_involved_in_sphingolipid_biosynthesis;_type_II_membrane_protein_with_similarity_to_Kre6p YGR144W THI4 MOL1|ESP35 mitochondrial_genome_maintenance* molecular_function_unknown mitochondrion* None None 7 780404 781384 YGR144W S000003376 "ORF,_Verified" "Thiazole_synthase,_catalyzes_formation_of_a_thiazole_intermediate_during_thiamine_biosynthesis;_required_for_mitochondrial_genome_stability_in_response_to_DNA_damaging_agents" YGR145W ENP2 None rRNA_processing molecular_function_unknown nucleolus None None 7 781772 783895 YGR145W S000003377 "ORF,_Verified" "Essential_nucleolar_protein_of_unknown_function;_contains_WD_repeats,_interacts_with_Mpp10p_and_Bfr2p,_and_has_homology_to_Spb1p" YGR146C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G2/M None 7 784863 784228 YGR146C S000003378 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_induced_by_iron_homeostasis_transcription_factor_Aft2p;_multicopy_suppressor_of_a_temperature_sensitive_hsf1_mutant;_induced_by_treatment_with_8-methoxypsoralen_and_UVA_irradiation YGR147C NAT2 None N-terminal_peptidyl-methionine_acetylation peptide_alpha-N-acetyltransferase_activity cytoplasm* None None 7 786925 786059 YGR147C S000003379 "ORF,_Verified" Protein_with_an_apparent_role_in_acetylation_of_N-terminal_methionine_residues YGR148C RPL24B RPL30B protein_biosynthesis structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 7 787784 787317 YGR148C S000003380 "ORF,_Verified" "Ribosomal_protein_L30_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl24Ap_and_has_similarity_to_rat_L24_ribosomal_protein;_not_essential_for_translation_but_may_be_required_for_normal_translation_rate" YGR149W None None biological_process_unknown molecular_function_unknown integral_to_membrane None None 7 789036 790334 YGR149W S000003381 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_predicted_to_be_an_integal_membrane_protein YGR152C RSR1 BUD1 bipolar_bud_site_selection* GTPase_activity* plasma_membrane* G1 None 7 795497 794679 YGR152C S000003384 "ORF,_Verified" "GTP-binding_protein_of_the_ras_superfamily_required_for_bud_site_selection,_morphological_changes_in_response_to_mating_pheromone,_and_efficient_cell_fusion;_localized_to_the_plasma_membrane;_significantly_similar_to_mammalian_Rap_GTPases" YGR153W None TOS10 biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 7 796097 796750 YGR153W S000003385 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YGR154C GTO1 None biological_process_unknown molecular_function_unknown peroxisome None None 7 797873 796803 YGR154C S000003386 "ORF,_Verified" Omega-class_glutathione_transferase;_induced_under_oxidative_stress;_putative_peroxisomal_localization YGR155W CYS4 VMA41|STR4|NHS5 cysteine_biosynthesis cystathionine_beta-synthase_activity cytoplasm* None None 7 798548 800071 YGR155W S000003387 "ORF,_Verified" "Cystathionine_beta-synthase,_catalyzes_the_synthesis_of_cystathionine_from_serine_and_homocysteine,_the_first_committed_step_in_cysteine_biosynthesis" YGR156W PTI1 None mRNA_polyadenylylation* RNA_binding nucleus* None None 7 800551 801828 YGR156W S000003388 "ORF,_Verified" Pta1p_Interacting_protein YGR157W CHO2 PEM1 phosphatidylcholine_biosynthesis phosphatidylethanolamine_N-methyltransferase_activity endoplasmic_reticulum None None 7 802445 805054 YGR157W S000003389 "ORF,_Verified" "Phosphatidylethanolamine_methyltransferase_(PEMT),_catalyzes_the_first_step_in_the_conversion_of_phosphatidylethanolamine_to_phosphatidylcholine_during_the_methylation_pathway_of_phosphatidylcholine_biosynthesis" YGR158C MTR3 None 35S_primary_transcript_processing* 3'-5'-exoribonuclease_activity nuclear_exosome_(RNase_complex)* None None 7 806026 805274 YGR158C S000003390 "ORF,_Verified" "3'5'_exoribonuclease,_exosome_subunit;_nucleolar_protein_involved_in_export_of_mRNA_and_ribosomal_subunits;_homologous_to_the_E._coli_exonuclease_RNase_PH" YGR159C NSR1 SHE5 rRNA_processing* RNA_binding* nucleus* None Down 7 807661 806417 YGR159C S000003391 "ORF,_Verified" "Nucleolar_protein_that_binds_nuclear_localization_sequences,_required_for_pre-rRNA_processing_and_ribosome_biogenesis" YGR161C RTS3 None protein_amino_acid_dephosphorylation protein_phosphatase_type_2A_activity cytoplasm* None None 7 809425 808634 YGR161C S000003393 "ORF,_Uncharacterized" Putative_component_of_the_protein_phosphatase_type_2A_complex YGR161C-C None None None None None None None 7 823020 821698 YGR161C-C S000007367 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YGR161C-D None None None None None None None 7 823020 817752 YGR161C-D S000007368 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YGR161W-A None None None None None None None 7 811743 813059 YGR161W-A S000007369 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YGR161W-B None None None None None None None 7 811743 817056 YGR161W-B S000007370 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YGR162W TIF4631 None translational_initiation translation_initiation_factor_activity mitochondrion* None None 7 824064 826922 YGR162W S000003394 "ORF,_Verified" "Translation_initiation_factor_eIF4G,_subunit_of_the_mRNA_cap-binding_protein_complex_(eIF4F)_that_also_contains_eIF4E_(Cdc33p);_associates_with_the_poly(A)-binding_protein_Pab1p,_also_interacts_with_eIF4A_(Tif1p);_homologous_to_Tif4632p" YGR165W MRPS35 None protein_biosynthesis* structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 7 829121 830158 YGR165W S000003397 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YGR166W KRE11 TRS65 ER_to_Golgi_transport molecular_function_unknown TRAPP_complex None None 7 830520 832202 YGR166W S000003398 "ORF,_Verified" "Protein_involved_in_biosynthesis_of_cell_wall_beta-glucans;_subunit_of_the_TRAPP_(transport_protein_particle)_complex,_which_is_involved_in_the_late_steps_of_endoplasmic_reticulum_to_Golgi_transport" YGR167W CLC1 SCD4 endocytosis* structural_molecule_activity clathrin_vesicle_coat None None 7 832461 833162 YGR167W S000003399 "ORF,_Verified" "Clathrin_light_chain,_subunit_of_the_major_coat_protein_involved_in_intracellular_protein_transport_and_endocytosis;_thought_to_regulate_clathrin_function;_two_Clathrin_heavy_chains_(CHC1)_form_the_clathrin_triskelion_structural_component" YGR168C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 834487 833357 YGR168C S000003400 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YGR168C_is_not_an_essential_gene YGR169C PUS6 None tRNA_modification* pseudouridylate_synthase_activity cytoplasm* None None 7 835908 834694 YGR169C S000003401 "ORF,_Verified" Pseudouridine_synthase_responsible_for_modification_of_cytoplasmic_and_mitochondrial_tRNAs_at_position_31;_mutation_of_Asp168_to_Ala_abolishes_enzyme_activity;_not_essential_for_viability YGR170W PSD2 None phosphatidylcholine_biosynthesis phosphatidylserine_decarboxylase_activity vacuolar_membrane_(sensu_Fungi)* None None 7 837147 840563 YGR170W S000003402 "ORF,_Verified" "Phosphatidylserine_decarboxylase_of_the_Golgi_and_vacuolar_membranes,_converts_phosphatidylserine_to_phosphatidylethanolamine" YGR171C MSM1 None methionyl-tRNA_aminoacylation methionine-tRNA_ligase_activity mitochondrion None None 7 842556 840829 YGR171C S000003403 "ORF,_Verified" "Mitochondrial_methionyl-tRNA_synthetase_(MetRS),_functions_as_a_monomer_in_mitochondrial_protein_synthesis;_functions_similarly_to_cytoplasmic_MetRS_although_the_cytoplasmic_form_contains_a_zinc-binding_domain_not_found_in_Msm1p" YGR172C YIP1 None ER_to_Golgi_transport* molecular_function_unknown endoplasmic_reticulum_membrane* None None 7 843596 842850 YGR172C S000003404 "ORF,_Verified" "Integral_membrane_protein_required_for_the_biogenesis_of_ER-derived_COPII_transport_vesicles;_interacts_with_Yif1p_and_Yos1p;_localizes_to_the_Golgi,_the_ER,_and_COPII_vesicles" YGR173W RBG2 GIR1 biological_process_unknown GTP_binding cytoplasm None None 7 843859 844965 YGR173W S000003405 "ORF,_Uncharacterized" Protein_with_similarity_to_mammalian_developmentally_regulated_GTP-binding_protein YGR174C CBP4 None protein_complex_assembly molecular_function_unknown mitochondrial_envelope None None 7 846410 845898 YGR174C S000003406 "ORF,_Verified" Mitochondrial_protein_required_for_assembly_of_ubiquinol_cytochrome-c_reductase_complex_(cytochrome_bc1_complex);_interacts_with_Cbp3p_and_function_is_partially_redundant_with_that_of_Cbp3p YGR175C ERG1 None ergosterol_biosynthesis squalene_monooxygenase_activity* endoplasmic_reticulum* None None 7 848428 846938 YGR175C S000003407 "ORF,_Verified" "Squalene_epoxidase,_catalyzes_the_epoxidation_of_squalene_to_2,3-oxidosqualene;_plays_an_essential_role_in_the_ergosterol-biosynthesis_pathway_and_is_the_specific_target_of_the_antifungal_drug_terbinafine" YGR177C ATF2 None steroid_metabolism alcohol_O-acetyltransferase_activity cytoplasm* G2/M None 7 850441 848834 YGR177C S000003409 "ORF,_Verified" "Alcohol_acetyltransferase,_may_play_a_role_in_steroid_detoxification;_forms_volatile_esters_during_fermentation,_which_is_important_in_brewing" YGR179C OKP1 None chromosome_segregation protein_binding condensed_nuclear_chromosome_kinetochore* None None 7 854900 853680 YGR179C S000003411 "ORF,_Verified" "Outer_kinetochore_protein,_required_for_accurate_mitotic_chromosome_segregation;_component_of_the_kinetochore_sub-complex_COMA_(Ctf19p,_Okp1p,_Mcm21p,_Ame1p)_that_functions_as_a_platform_for_kinetochore_assembly" YGR181W TIM13 None protein_import_into_mitochondrial_inner_membrane protein_transporter_activity mitochondrial_intermembrane_space* None None 7 858292 858609 YGR181W S000003413 "ORF,_Verified" "Mitochondrial_intermembrane_space_protein,_forms_a_complex_with_TIm8p_that_mediates_import_and_insertion_of_a_subset_of_polytopic_inner_membrane_proteins;_may_prevent_aggregation_of_incoming_proteins_in_a_chaperone-like_manner" YGR183C QCR9 UCR9 aerobic_respiration* ubiquinol-cytochrome-c_reductase_activity respiratory_chain_complex_III_(sensu_Eukaryota) None None 7 859481 859068 YGR183C S000003415 "ORF,_Verified" "Subunit_9_of_the_ubiquinol_cytochrome-c_reductase_complex,_which_is_a_component_of_the_mitochondrial_inner_membrane_electron_transport_chain;_required_for_electron_transfer_at_the_ubiquinol_oxidase_site_of_the_complex" YGR184C UBR1 PTR1 protein_monoubiquitination* ubiquitin-protein_ligase_activity proteasome_complex_(sensu_Eukaryota) None None 7 865758 859906 YGR184C S000003416 "ORF,_Verified" "Ubiquitin-protein_ligase_(E3)_that_interacts_with_Rad6p/Ubc2p_to_ubiquitinate_substrates_of_the_N-end_rule_pathway;_binds_to_the_Rpn2p,_Rpt1p,_and_Rpt6p_proteins_of_the_19S_particle_of_the_26S_proteasome" YGR186W TFG1 RAP74|SSU71 transcription_initiation_from_RNA_polymerase_II_promoter general_RNA_polymerase_II_transcription_factor_activity transcription_factor_TFIIF_complex None None 7 867779 869986 YGR186W S000003418 "ORF,_Verified" TFIIF_(Transcription_Factor_II)_largest_subunit;_involved_in_both_transcription_initiation_and_elongation_of_RNA_polymerase_II;_homologous_to_human_RAP74 YGR187C HGH1 None biological_process_unknown molecular_function_unknown cytoplasm None None 7 871421 870237 YGR187C S000003419 "ORF,_Verified" Nonessential_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_similar_to_mammalian_BRP16_(Brain_protein_16) YGR188C BUB1 None protein_amino_acid_phosphorylation* protein_binding* nucleus* G1 None 7 875114 872049 YGR188C S000003420 "ORF,_Verified" "Protein_kinase_that_forms_a_complex_with_Mad1p_and_Bub3p_that_is_crucial_in_the_checkpoint_mechanism_required_to_prevent_cell_cycle_progression_into_anaphase_in_the_presence_of_spindle_damage,_associates_with_centromere_DNA_via_Skp1p" YGR189C CRH1 None biological_process_unknown molecular_function_unknown cell_wall_(sensu_Fungi)* G1 None 7 878197 876674 YGR189C S000003421 "ORF,_Verified" "Putative_chitin_transglycosidase,_cell_wall_protein_that_functions_in_the_transfer_of_chitin_to_beta(1-6)glucan;_localizes_to_sites_of_polarized_growth;_expression_is_induced_under_cell_wall_stress_conditions" YGR191W HIP1 None manganese_ion_transport* L-histidine_transporter_activity plasma_membrane None None 7 880425 882236 YGR191W S000003423 "ORF,_Verified" "High-affinity_histidine_permease,_also_involved_in_the_transport_of_manganese_ions" YGR192C TDH3 SSS2|HSP36|HSP35|GLD1 glycolysis* glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating)_activity cytoplasm* None None 7 883815 882817 YGR192C S000003424 "ORF,_Verified" "Glyceraldehyde-3-phosphate_dehydrogenase,_isozyme_3,_involved_in_glycolysis_and_gluconeogenesis;_tetramer_that_catalyzes_the_reaction_of_glyceraldehyde-3-phosphate_to_1,3_bis-phosphoglycerate;_detected_in_the_cytoplasm_and_cell-wall" YGR194C XKS1 None xylulose_catabolism xylulokinase_activity cytoplasm None None 7 887880 886078 YGR194C S000003426 "ORF,_Verified" "Xylulokinase,_converts_D-xylulose_and_ATP_to_xylulose_5-phosphate_and_ADP;_rate_limiting_step_in_fermentation_of_xylulose;_required_for_xylose_fermentation_by_recombinant_S._cerevisiae_strains" YGR196C FYV8 None biological_process_unknown molecular_function_unknown cytoplasm None None 7 892191 889738 YGR196C S000003428 "ORF,_Verified" "Protein_of_unknown_function,_required_for_survival_upon_exposure_to_K1_killer_toxin" YGR197C SNG1 None response_to_drug molecular_function_unknown membrane None None 7 894145 892502 YGR197C S000003429 "ORF,_Verified" Protein_involved_in_nitrosoguanidine_(MNNG)_resistance;_expression_is_regulated_by_transcription_factors_involved_in_multidrug_resistance YGR199W PMT6 None protein_amino_acid_O-linked_glycosylation dolichyl-phosphate-mannose-protein_mannosyltransferase_activity endoplasmic_reticulum None None 7 897507 899786 YGR199W S000003431 "ORF,_Verified" "Protein_O-mannosyltransferase,_transfers_mannose_from_dolichyl_phosphate-D-mannose_to_protein_serine/threonine_residues_of_secretory_proteins;_reaction_is_essential_for_cell_wall_rigidity;_member_of_a_family_of_mannosyltransferases" YGR201C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 903202 902525 YGR201C S000003433 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YGR202C PCT1 CCT1|BSR2 phosphatidylcholine_biosynthesis* choline-phosphate_cytidylyltransferase_activity nucleus* None None 7 904753 903479 YGR202C S000003434 "ORF,_Verified" "Cholinephosphate_cytidylyltransferase,_also_known_as_CTP:phosphocholine_cytidylyltransferase,_rate-determining_enzyme_of_the_CDP-choline_pathway_for_phosphatidylcholine_synthesis,_inhibited_by_Sec14p,_activated_upon_lipid-binding" YGR203W None None biological_process_unknown protein_tyrosine_phosphatase_activity* cytoplasm* None None 7 905242 905688 YGR203W S000003435 "ORF,_Uncharacterized" Putative_protein_with_sequence_similarity_to_protein_tyrosine_phosphatases_of_the_CDC25-like_phosphatase_family;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_both_the_cytoplasm_and_the_nucleus YGR204W ADE3 None purine_base_biosynthesis* formate-tetrahydrofolate_ligase_activity* cytoplasm* None None 7 905939 908779 YGR204W S000003436 "ORF,_Verified" "Cytoplasmic_trifunctional_enzyme_C1-tetrahydrofolate_synthase,_involved_in_single_carbon_metabolism_and_required_for_biosynthesis_of_purines,_thymidylate,_methionine,_and_histidine" YGR205W None None biological_process_unknown ATP_binding cytoplasm* None None 7 909218 910090 YGR205W S000003437 "ORF,_Verified" ATP-binding_protein_of_unknown_function;_crystal_structure_resembles_that_of_E.coli_pantothenate_kinase_and_other_small_kinases YGR206W MVB12 None biological_process_unknown molecular_function_unknown endosome None None 7 910437 910742 YGR206W S000003438 "ORF,_Verified" "ESCRT-I_subunit_required_to_stabilize_oligomers_of_the_ESCRT-I_core_complex_(Stp22p,_Vps28p,_Srn2p),_which_is_involved_in_ubiquitin-dependent_sorting_of_proteins_into_the_endosome;_deletion_mutant_is_sensitive_to_rapamycin_and_nystatin" YGR207C None None biological_process_unknown molecular_function_unknown mitochondrion None None 7 911633 910848 YGR207C S000003439 "ORF,_Verified" "Protein_that_interacts_with_frataxin_(Yfh1p);_putative_homolog_of_mammalian_electron_transfer_flavoprotein_complex_subunit_ETF-beta;_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YGR208W SER2 None serine_family_amino_acid_biosynthesis phosphoserine_phosphatase_activity cytoplasm* None None 7 911888 912817 YGR208W S000003440 "ORF,_Verified" "Phosphoserine_phosphatase_of_the_phosphoglycerate_pathway,_involved_in_serine_and_glycine_biosynthesis,_expression_is_regulated_by_the_available_nitrogen_source" YGR209C TRX2 LMA1 ER_to_Golgi_transport* thiol-disulfide_exchange_intermediate_activity cytosol* None None 7 913232 912918 YGR209C S000003441 "ORF,_Verified" "Cytoplasmic_thioredoxin_isoenzyme_of_the_thioredoxin_system_which_protects_cells_against_oxidative_and_reductive_stress,_forms_LMA1_complex_with_Pbi2p,_acts_as_a_cofactor_for_Tsa1p,_required_for_ER-Golgi_transport_and_vacuole_inheritance" YGR210C None None biological_process_unknown molecular_function_unknown cytoplasm None None 7 914743 913508 YGR210C S000003442 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YGR211W ZPR1 None regulation_of_progression_through_cell_cycle protein_binding cytoplasm* None None 7 915246 916706 YGR211W S000003443 "ORF,_Verified" "Essential_protein_with_two_zinc_fingers,_present_in_the_nucleus_of_growing_cells_but_relocates_to_the_cytoplasm_in_starved_cells_via_a_process_mediated_by_Cpr1p;_binds_to_translation_elongation_factor_eEF-1_(Tef1p)" YGR212W SLI1 None response_to_drug N-acetyltransferase_activity plasma_membrane* None None 7 917045 918451 YGR212W S000003444 "ORF,_Verified" "N-acetyltransferase,_confers_resistance_to_the_sphingolipid_biosynthesis_inhibitor_myriocin_(ISP-1)_by_converting_it_into_N-acetyl-myriocin,_co-operates_with_Ypk1p_in_mediating_resistance_to_myriocin" YGR213C RTA1 None biological_process_unknown molecular_function_unknown integral_to_membrane None None 7 919470 918517 YGR213C S000003445 "ORF,_Verified" Protein_involved_in_7-aminocholesterol_resistance;_has_seven_potential_membrane-spanning_regions;_expression_is_induced_under_both_low-heme_and_low-oxygen_conditions YGR214W RPS0A YST1|NAB1A|NAB1 protein_biosynthesis* structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 7 920580 921793 YGR214W S000003446 "ORF,_Verified" "Protein_component_of_the_small_(40S)_ribosomal_subunit,_nearly_identical_to_Rps0Bp;_required_for_maturation_of_18S_rRNA_along_with_Rps0Bp;_deletion_of_either_RPS0_gene_reduces_growth_rate,_deletion_of_both_genes_is_lethal" YGR215W RSM27 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 7 922180 922512 YGR215W S000003447 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YGR216C GPI1 None GPI_anchor_biosynthesis UDP-glycosyltransferase_activity membrane* None None 7 924467 922638 YGR216C S000003448 "ORF,_Verified" "Membrane_protein_involved_in_the_synthesis_of_N-acetylglucosaminyl_phosphatidylinositol_(GlcNAc-PI),_the_first_intermediate_in_the_synthesis_of_glycosylphosphatidylinositol_(GPI)_anchors;_human_and_mouse_GPI1p_are_functional_homologs" YGR217W CCH1 None calcium_ion_transport calcium_channel_activity plasma_membrane None None 7 924699 930818 YGR217W S000003449 "ORF,_Verified" "Voltage-gated_high-affinity_calcium_channel_involved_in_calcium_influx_in_response_to_some_environmental_stresses_as_well_as_exposure_to_mating_pheromones;_interacts_and_co-localizes_with_Mid1p,_suggesting_Cch1p_and_Mid1p_function_together" YGR218W CRM1 XPO1|KAP124 mRNA_export_from_nucleus* protein_carrier_activity nucleus None Up 7 932544 935798 YGR218W S000003450 "ORF,_Verified" "Major_karyopherin,_involved_in_export_of_proteins,_RNAs,_and_ribosomal_subunits_from_the_nucleus;_exportin" YGR220C MRPL9 None protein_biosynthesis* structural_constituent_of_ribosome* mitochondrial_large_ribosomal_subunit None None 7 936886 936077 YGR220C S000003452 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YGR221C TOS2 None budding_cell_bud_growth molecular_function_unknown bud_neck* G1 None 7 938995 937127 YGR221C S000003453 "ORF,_Verified" Protein_involved_in_localization_of_Cdc24p_to_the_site_of_bud_growth;_may_act_as_a_membrane_anchor;_localizes_to_the_bud_neck_and_bud_tip;_potentially_phosphorylated_by_Cdc28p YGR223C HSV2 None biological_process_unknown phosphoinositide_binding cytoplasm* None Up 7 942218 940872 YGR223C S000003455 "ORF,_Verified" "Phosphatidylinositol_3,5-bisphosphate-binding_protein,_predicted_to_fold_as_a_seven-bladed_beta-propeller;_displays_punctate_cytoplasmic_localization" YGR225W AMA1 SPO70 sporulation_(sensu_Fungi)* enzyme_activator_activity anaphase-promoting_complex None None 7 945148 947022 YGR225W S000003457 "ORF,_Verified" Activator_of_meiotic_anaphase_promoting_complex_(APC/C);_Cdc20p_family_member;_required_for_initiation_of_spore_wall_assembly;_required_for_Clb1p_degradation_during_meiosis YGR227W DIE2 ALG10 protein_amino_acid_N-linked_glycosylation* dolichyl-phosphate-glucose-glycolipid_alpha-glucosyltransferase_activity endoplasmic_reticulum_membrane None None 7 947423 949000 YGR227W S000003459 "ORF,_Verified" "Dolichyl-phosphoglucose-dependent_alpha-1,2_glucosyltransferase_of_the_ER,_functions_in_the_pathway_that_synthesizes_the_dolichol-linked_oligosaccharide_precursor_for_N-linked_protein_glycosylation,_has_a_role_in_regulation_of_ITR1_and_INO1" YGR229C SMI1 KNR4 cell_wall_organization_and_biogenesis* molecular_function_unknown nucleus* None None 7 950902 949385 YGR229C S000003461 "ORF,_Verified" Protein_involved_in_the_regulation_of_cell_wall_synthesis;_proposed_to_be_involved_in_coordinating_cell_cycle_progression_with_cell_wall_integrity YGR231C PHB2 None protein_folding* molecular_function_unknown mitochondrion* None None 7 953483 952551 YGR231C S000003463 "ORF,_Verified" "Subunit_of_the_prohibitin_complex_(Phb1p-Phb2p),_a_1.2_MDa_ring-shaped_inner_mitochondrial_membrane_chaperone_that_stabilizes_newly_synthesized_proteins;_determinant_of_replicative_life_span;_involved_in_mitochondrial_segregation" YGR232W NAS6 None proteolysis molecular_function_unknown proteasome_regulatory_particle_(sensu_Eukaryota) None None 7 953963 954649 YGR232W S000003464 "ORF,_Verified" "Regulatory,_non-ATPase_subunit_of_the_26S_proteasome;_homolog_of_the_human_oncoprotein_gankyrin,_which_interacts_with_the_retinoblastoma_tumor_suppressor_(Rb)_and_cyclin-dependent_kinase_4/6" YGR233C PHO81 phoS phosphate_metabolism cyclin-dependent_protein_kinase_inhibitor_activity cytoplasm* None None 7 958213 954677 YGR233C S000003465 "ORF,_Verified" "Cyclin-dependent_kinase_(CDK)_inhibitor,_regulates_Pho80p-Pho85p_and_Pcl7p-Pho85p_cyclin-CDK_complexes_in_response_to_phosphate_levels;_inhibitory_activity_for_Pho80p-Pho85p_requires_myo-D-inositol_heptakisphosphate_(IP7)_generated_by_Vip1p" YGR234W YHB1 YHB4 response_to_stress nitric_oxide_reductase_activity cytoplasm* M/G1 Up 7 959908 961107 YGR234W S000003466 "ORF,_Verified" "Nitric_oxide_oxidoreductase,_flavohemoglobin_involved_in_nitric_oxide_detoxification;_plays_a_role_in_the_oxidative_and_nitrosative_stress_responses" YGR235C None None biological_process_unknown molecular_function_unknown mitochondrion None None 7 962065 961364 YGR235C S000003467 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YGR237C None None biological_process_unknown molecular_function_unknown cytoplasm None Up 7 965660 963303 YGR237C S000003469 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YGR238C KEL2 None conjugation_with_cellular_fusion* molecular_function_unknown bud_neck* G1 None 7 968692 966044 YGR238C S000003470 "ORF,_Verified" "Protein_that_functions_in_a_complex_with_Kel1p_to_negatively_regulate_mitotic_exit,_interacts_with_Tem1p_and_Lte1p;_localizes_to_regions_of_polarized_growth;_potential_Cdc28p_substrate" YGR240C PFK1 None glycolysis 6-phosphofructokinase_activity cytoplasm* G2/M None 7 973739 970776 YGR240C S000003472 "ORF,_Verified" "Alpha_subunit_of_heterooctameric_phosphofructokinase_involved_in_glycolysis,_indispensable_for_anaerobic_growth,_activated_by_fructose-2,6-bisphosphate_and_AMP,_mutation_inhibits_glucose_induction_of_cell_cycle-related_genes" YGR241C YAP1802 None endocytosis clathrin_binding actin_cortical_patch None None 7 976586 974880 YGR241C S000003473 "ORF,_Verified" "Protein_involved_in_clathrin_cage_assembly;_binds_Pan1p_and_clathrin;_homologous_to_Yap1801p,_member_of_the_AP180_protein_family" YGR243W FMP43 None biological_process_unknown molecular_function_unknown mitochondrion None None 7 977341 977781 YGR243W S000003475 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YGR244C LSC2 None tricarboxylic_acid_cycle* succinate-CoA_ligase_(ADP-forming)_activity mitochondrion None Up 7 979324 978041 YGR244C S000003476 "ORF,_Verified" "Beta_subunit_of_succinyl-CoA_ligase,_which_is_a_mitochondrial_enzyme_of_the_TCA_cycle_that_catalyzes_the_nucleotide-dependent_conversion_of_succinyl-CoA_to_succinate" YGR245C SDA1 None actin_cytoskeleton_organization_and_biogenesis* molecular_function_unknown nucleus None None 7 982073 979770 YGR245C S000003477 "ORF,_Verified" "Highly_conserved_nuclear_protein_required_for_actin_cytoskeleton_organization_and_passage_through_Start,_plays_a_critical_role_in_G1_events,_binds_Nap1p,_also_involved_in_60S_ribosome_biogenesis" YGR246C BRF1 TDS4|PCF4 transcription_initiation_from_RNA_polymerase_III_promoter RNA_polymerase_III_transcription_factor_activity transcription_factor_TFIIIB_complex None None 7 984277 982487 YGR246C S000003478 "ORF,_Verified" "TFIIIB_B-related_factor,_one_of_three_subunits_of_RNA_polymerase_III_transcription_initiation_factor_TFIIIB,_binds_TFIIIC_and_TBP_and_recruits_RNA_pol_III_to_promoters,_amino-terminal_half_is_homologous_to_TFIIB" YGR247W CPD1 None meiosis* "2',3'-cyclic-nucleotide_3'-phosphodiesterase_activity" clathrin-coated_vesicle None None 7 984971 985690 YGR247W S000003479 "ORF,_Verified" "Cyclic_nucleotide_phosphodiesterase,_hydrolyzes_ADP-ribose_1'',_2''-cyclic_phosphate_to_ADP-ribose_1''-phosphate;_may_have_a_role_in_tRNA_splicing;_no_detectable_phenotype_is_conferred_by_null_mutation_or_by_overexpression" YGR248W SOL4 None "pentose-phosphate_shunt,_oxidative_branch" 6-phosphogluconolactonase_activity cytoplasm* None None 7 985977 986744 YGR248W S000003480 "ORF,_Verified" 6-phosphogluconolactonase_with_similarity_to_Sol3p YGR249W MGA1 None filamentous_growth molecular_function_unknown cellular_component_unknown None None 7 988054 989424 YGR249W S000003481 "ORF,_Verified" Protein_similar_to_heat_shock_transcription_factor;_multicopy_suppressor_of_pseudohyphal_growth_defects_of_ammonium_permease_mutants YGR250C None None biological_process_unknown RNA_binding cytoplasm None None 7 993526 991181 YGR250C S000003482 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YGR251W None None 35S_primary_transcript_processing molecular_function_unknown nucleus* None None 7 995644 996234 YGR251W S000003483 "ORF,_Uncharacterized" Essential_protein_required_for_maturation_of_18S_rRNA;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_both_the_nucleus_and_the_nucleolus YGR252W GCN5 SWI9|ADA4 histone_acetylation* histone_acetyltransferase_activity* SAGA_complex* None None 7 996874 998193 YGR252W S000003484 "ORF,_Verified" "Histone_acetyltransferase,_acetylates_N-terminal_lysines_on_histones_H2B_and_H3;_catalytic_subunit_of_the_ADA_and_SAGA_histone_acetyltransferase_complexes;_founding_member_of_the_Gcn5p-related_N-acetyltransferase_superfamily" YGR254W ENO1 HSP48 glycolysis* phosphopyruvate_hydratase_activity cytoplasm* None None 7 1000932 1002245 YGR254W S000003486 "ORF,_Verified" "Enolase_I,_a_phosphopyruvate_hydratase_that_catalyzes_the_conversion_of_2-phosphoglycerate_to_phosphoenolpyruvate_during_glycolysis_and_the_reverse_reaction_during_gluconeogenesis;_expression_is_repressed_in_response_to_glucose" YGR255C COQ6 None ubiquinone_metabolism ubiquinone_biosynthesis_monooxygenase_activity mitochondrion* None None 7 1003967 1002528 YGR255C S000003487 "ORF,_Verified" "Putative_flavin-dependent_monooxygenase,_involved_in_ubiquinone_(Coenzyme_Q)_biosynthesis;_localizes_to_the_matrix_face_of_the_mitochondrial_inner_membrane_in_a_large_complex_with_other_ubiquinone_biosynthetic_enzymes" YGR256W GND2 None glucose_metabolism phosphogluconate_dehydrogenase_(decarboxylating)_activity cytosol None None 7 1004630 1006108 YGR256W S000003488 "ORF,_Verified" "6-phosphogluconate_dehydrogenase_(decarboxylating),_catalyzes_an_NADPH_regenerating_reaction_in_the_pentose_phosphate_pathway;_required_for_growth_on_D-glucono-delta-lactone" YGR257C MTM1 None transport* transporter_activity* mitochondrion* None None 7 1007311 1006211 YGR257C S000003489 "ORF,_Verified" "Mitochondrial_protein_of_the_mitochondrial_carrier_family,_involved_in_activating_mitochondrial_Sod2p_probably_by_facilitating_insertion_of_an_essential_manganese_cofactor" YGR260W TNA1 None nicotinamide_mononucleotide_transport nicotinamide_mononucleotide_permease_activity mitochondrion* G2/M None 7 1012491 1014095 YGR260W S000003492 "ORF,_Verified" "High_affinity_nicotinic_acid_plasma_membrane_permease,_responsible_for_uptake_of_low_levels_of_nicotinic_acid;_expression_of_the_gene_increases_in_the_absence_of_extracellular_nicotinic_acid_or_para-aminobenzoate_(PABA)" YGR262C BUD32 LDB14 protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity cytoplasm* None None 7 1017765 1016980 YGR262C S000003494 "ORF,_Verified" "Protein_kinase_proposed_to_be_involved_in_bud-site_selection,_telomere_uncapping_and_elongation,_and_transcription;_component_of_the_EKC/KEOPS_protein_complex_with_Kae1p,_Cgi121p,_Pcc1p,_and_Gon7p" YGR263C SAY1 None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 7 1019247 1017973 YGR263C S000003495 "ORF,_Verified" Sterol_deacetylase;_component_of_the_sterol_acetylation/deacetylation_cycle_along_with_Atf2p;_integral_membrane_protein_with_active_site_in_the_ER_lumen;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_endoplasmic_reticulum YGR264C MES1 MESI methionyl-tRNA_aminoacylation methionine-tRNA_ligase_activity cytoplasm* None None 7 1021859 1019604 YGR264C S000003496 "ORF,_Verified" "Methionyl-tRNA_synthetase,_forms_a_complex_with_glutamyl-tRNA_synthetase_(Gus1p)_and_Arc1p,_which_increases_the_catalytic_efficiency_of_both_tRNA_synthetases;_also_has_a_role_in_nuclear_export_of_tRNAs" YGR266W None None biological_process_unknown molecular_function_unknown mitochondrion* None None 7 1022662 1024767 YGR266W S000003498 "ORF,_Verified" "Protein_of_unknown_function,_predicted_to_contain_a_single_transmembrane_domain;_localized_to_both_the_mitochondrial_outer_membrane_and_the_plasma_membrane" YGR267C FOL2 None folic_acid_and_derivative_biosynthesis GTP_cyclohydrolase_I_activity cytoplasm* None None 7 1025741 1025010 YGR267C S000003499 "ORF,_Verified" "GTP-cyclohydrolase_I,_catalyzes_the_first_step_in_the_folic_acid_biosynthetic_pathway" YGR268C HUA1 None actin_cortical_patch_assembly molecular_function_unknown cytoplasm None None 7 1026659 1026063 YGR268C S000003500 "ORF,_Verified" Cytoplasmic_protein_containing_a_zinc_finger_domain_with_sequence_similarity_to_that_of_Type_I_J-proteins;_computational_analysis_of_large-scale_protein-protein_interaction_data_suggests_a_possible_role_in_actin_patch_assembly YGR271C-A EFG1 YGR272C biological_process_unknown molecular_function_unknown nucleolus None None 7 1038507 1037806 YGR272C S000007608 "ORF,_Verified" Essential_protein_required_for_maturation_of_18S_rRNA;_null_mutant_is_sensitive_to_hydroxyurea_and_is_delayed_in_recovering_from_alpha-factor_arrest;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleolus YGR271W SLH1 None regulation_of_translation RNA_helicase_activity cytoplasm None None 7 1031797 1037700 YGR271W S000003503 "ORF,_Verified" "Putative_RNA_helicase_related_to_Ski2p,_involved_in_translation_inhibition_of_non-poly(A)_mRNAs;_required_for_repressing_propagation_of_dsRNA_viruses" YGR273C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 1039245 1038721 YGR273C S000003505 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_that_binds_Ilm1p;_deletion_mutant_has_no_readily_detectable_phenotype;_expression_downregulated_by_treatment_with_8-methoxypsoralen_plus_UVA_irradiation YGR274C TAF1 TAF145|TAF130 protein_amino_acid_phosphorylation* general_RNA_polymerase_II_transcription_factor_activity* transcription_factor_TFIID_complex None None 7 1043102 1039902 YGR274C S000003506 "ORF,_Verified" "TFIID_subunit_(145_kDa),_involved_in_RNA_polymerase_II_transcription_initiation,_has_histone_acetyltransferase_activity,_involved_in_promoter_binding_and_G1/S_progression" YGR275W RTT102 None biological_process_unknown molecular_function_unknown nucleus* None None 7 1043283 1043756 YGR275W S000003507 "ORF,_Verified" "Component_of_both_the_SWI/SNF_and_RSC_chromatin_remodeling_complexes,_suggested_role_in_chromosome_maintenance;_possible_weak_regulator_of_Ty1_transposition" YGR276C RNH70 RNA82|REX1 DNA_replication* 3'-5'_exonuclease_activity nucleus M/G1 None 7 1045487 1043826 YGR276C S000003508 "ORF,_Verified" 3'-5'_exoribonuclease;_required_for_maturation_of_3'_ends_of_5S_rRNA_and_tRNA-Arg3_from_dicistronic_transcripts YGR277C None None coenzyme_A_biosynthesis pantetheine-phosphate_adenylyltransferase_activity cytoplasm* None None 7 1046568 1045651 YGR277C S000003509 "ORF,_Uncharacterized" "Putative_pantetheine-phosphate_adenylyltransferase_(PPAT)_that_catalyzes_the_fourth_step_in_the_biosynthesis_of_coenzyme_A_from_pantothenate;_conserved_in_bacteria,_humans,_and_plants;_essential_for_viability" YGR278W CWC22 None "nuclear_mRNA_splicing,_via_spliceosome" molecular_function_unknown spliceosome_complex None None 7 1046738 1048471 YGR278W S000003510 "ORF,_Verified" "Essential_protein,_component_of_a_complex_containing_Cef1p,_has_similarity_to_S._pombe_Cwf22p;_putative_spliceosomal_component,_based_on_computational_analysis_of_large-scale_protein-protein_interaction_data" YGR279C SCW4 None conjugation_with_cellular_fusion glucosidase_activity cell_wall_(sensu_Fungi) G2/M None 7 1049965 1048805 YGR279C S000003511 "ORF,_Verified" Cell_wall_protein_with_similarity_to_glucanases;_scw4_scw10_double_mutants_exhibit_defects_in_mating YGR280C PXR1 GNO1 35S_primary_transcript_processing* RNA_binding nucleolus None Down 7 1051732 1050917 YGR280C S000003512 "ORF,_Verified" "Essential_protein_involved_in_rRNA_and_snoRNA_maturation;_competes_with_TLC1_RNA_for_binding_to_Est2p,_suggesting_a_role_in_negative_regulation_of_telomerase;_human_homolog_inhibits_telomerase;_contains_a_G-patch_RNA_interacting_domain" YGR281W YOR1 YRS1 transport* xenobiotic-transporting_ATPase_activity plasma_membrane None None 7 1052831 1057264 YGR281W S000003513 "ORF,_Verified" "Plasma_membrane_ATP-binding_cassette_(ABC)_transporter,_multidrug_transporter_mediates_export_of_many_different_organic_anions_including_oligomycin" YGR282C BGL2 None cell_wall_organization_and_biogenesis "glucan_1,3-beta-glucosidase_activity" cell_wall_(sensu_Fungi) None None 7 1058731 1057790 YGR282C S000003514 "ORF,_Verified" "Endo-beta-1,3-glucanase,_major_protein_of_the_cell_wall,_involved_in_cell_wall_maintenance" YGR284C ERV29 None ER_to_Golgi_transport molecular_function_unknown COPII-coated_vesicle G2/M None 7 1061597 1060665 YGR284C S000003516 "ORF,_Verified" "Protein_localized_to_COPII-coated_vesicles,_involved_in_vesicle_formation_and_incorporation_of_specific_secretory_cargo" YGR285C ZUO1 None protein_folding unfolded_protein_binding cytoplasm* None None 7 1063160 1061859 YGR285C S000003517 "ORF,_Verified" "Cytosolic_ribosome-associated_chaperone_that_acts,_together_with_Ssz1p_and_the_Ssb_proteins,_as_a_chaperone_for_nascent_polypeptide_chains;_contains_a_DnaJ_domain_and_functions_as_a_J-protein_partner_for_Ssb1p_and_Ssb2p" YGR286C BIO2 None biotin_biosynthesis biotin_synthase_activity mitochondrion None None 7 1064947 1063820 YGR286C S000003518 "ORF,_Verified" "Biotin_synthase,_catalyzes_the_conversion_of_dethiobiotin_to_biotin,_which_is_the_last_step_of_the_biotin_biosynthesis_pathway;_complements_E._coli_bioB_mutant" YGR288W MAL13 MALR "regulation_of_transcription,_DNA-dependent*" transcription_factor_activity nucleus None None 7 1070300 1071721 YGR288W S000003520 "ORF,_Verified" "MAL-activator_protein,_part_of_complex_locus_MAL1;_nonfunctional_in_genomic_reference_strain_S288C" YGR292W MAL12 MALS maltose_catabolism alpha-glucosidase_activity cellular_component_unknown None None 7 1076606 1078360 YGR292W S000003524 "ORF,_Verified" "Maltase_(alpha-D-glucosidase),_inducible_protein_involved_in_maltose_catabolism;_encoded_in_the_MAL1_complex_locus" YGR294W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 7 1080313 1080675 YGR294W S000003526 "ORF,_Uncharacterized" Hypothetical_protein YGR295C COS6 None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) None None 7 1082736 1081591 YGR295C S000003527 "ORF,_Verified" "Protein_of_unknown_function,_member_of_the_DUP380_subfamily_of_conserved,_often_subtelomerically-encoded_proteins" YGR296W YRF1-3 YRF1 telomerase-independent_telomere_maintenance DNA_helicase_activity nucleus G1 None 7 1084871 1090598 YGR296W S000003528 "ORF,_Verified" "Helicase_encoded_by_the_Y'_element_of_subtelomeric_regions,_highly_expressed_in_the_mutants_lacking_the_telomerase_component_TLC1;_potentially_phosphorylated_by_Cdc28p" YHL001W RPL14B None protein_biosynthesis structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 8 104272 105086 YHL001W S000000993 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl14Ap_and_has_similarity_to_rat_L14_ribosomal_protein" YHL002W HSE1 None protein_targeting_to_vacuole protein_binding endosome None None 8 102607 103965 YHL002W S000000994 "ORF,_Verified" "Subunit_of_the_endosomal_Vps27p-Hse1p_complex_required_for_sorting_of_ubiquitinated_membrane_proteins_into_intralumenal_vesicles_prior_to_vacuolar_degradation,_as_well_as_for_recycling_of_Golgi_proteins_and_formation_of_lumenal_membranes" YHL003C LAG1 None replicative_cell_aging* sphingosine_N-acyltransferase_activity endoplasmic_reticulum None None 8 101879 100644 YHL003C S000000995 "ORF,_Verified" "Ceramide_synthase_component,_involved_in_synthesis_of_ceramide_from_C26(acyl)-coenzyme_A_and_dihydrosphingosine_or_phytosphingosine,_functionally_equivalent_to_Lac1p" YHL004W MRP4 None protein_biosynthesis structural_constituent_of_ribosome* mitochondrial_small_ribosomal_subunit None None 8 99215 100399 YHL004W S000000996 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YHL006C SHU1 None error-free_DNA_repair molecular_function_unknown nucleus None None 8 98791 98339 YHL006C S000000998 "ORF,_Verified" "Protein_of_unassigned_function_involved_in_mutation_suppression,_important_for_error-free_repair_of_spontaneous_and_induced_DNA_lesions_to_protect_the_genome_from_mutation;_associates_with_Shu2p,_Psy3p,_and_Csm2p" YHL007C STE20 None protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity incipient_bud_site* None None 8 97933 95114 YHL007C S000000999 "ORF,_Verified" "Signal_transducing_kinase_of_the_PAK_(p21-activated_kinase)_family,_involved_in_pheromone_response_and_pseudohyphal/invasive_growth_pathways,_activated_by_Cdc42p;_binds_Ste4p_at_a_GBB_motif_present_in_noncatalytic_domains_of_PAK_kinases" YHL008C None None biological_process_unknown* transporter_activity* vacuole_(sensu_Fungi) None None 8 94506 92623 YHL008C S000001000 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_does_not_appear_to_be_involved_in_monocarboxylic_acid_transport;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuole" YHL009C YAP3 None regulation_of_transcription_from_RNA_polymerase_II_promoter transcription_factor_activity nucleus None None 8 85056 84064 YHL009C S000001001 "ORF,_Verified" Basic_leucine_zipper_(bZIP)_transcription_factor YHL009W-A None None None None None None None 8 85905 87146 YHL009W-A S000007371 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YHL009W-B None None None None None None None 8 85905 91314 YHL009W-B S000007372 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YHL010C None None biological_process_unknown nuclear_localization_sequence_binding cellular_component_unknown None None 8 83717 81960 YHL010C S000001002 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_contains_a_zinc_finger_region_and_has_homology_to_human_BRAP2,_which_is_a_cytoplasmic_protein_that_binds_nuclear_localization_sequences" YHL012W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 78932 80413 YHL012W S000001004 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_has_some_homology_to_Ugp1p,_which_encodes_UDP-glucose_pyrophosphorylase" YHL013C OTU2 None biological_process_unknown molecular_function_unknown cytoplasm None None 8 78350 77427 YHL013C S000001005 "ORF,_Verified" "Protein_of_unknown_function_that_may_interact_with_ribosomes,_based_on_co-purification_experiments;_member_of_the_ovarian_tumor-like_(OTU)_superfamily_of_predicted_cysteine_proteases;_shows_cytoplasmic_localization" YHL014C YLF2 YLF1 biological_process_unknown GTP_binding mitochondrion None None 8 77311 76094 YHL014C S000001006 "ORF,_Verified" "Protein_of_unknown_function,_has_weak_similarity_to_E._coli_GTP-binding_protein_gtp1;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YHL015W RPS20 URP2 protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 8 75409 75774 YHL015W S000001007 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_overproduction_suppresses_mutations_affecting_RNA_polymerase_III-dependent_transcription;_has_similarity_to_E._coli_S10_and_rat_S20_ribosomal_proteins YHL016C DUR3 None urea_transport urea_transporter_activity plasma_membrane None None 8 74241 72034 YHL016C S000001008 "ORF,_Verified" "Plasma_membrane_transporter_for_both_urea_and_polyamines,_expression_is_highly_sensitive_to_nitrogen_catabolite_repression_and_induced_by_allophanate,_the_last_intermediate_of_the_allantoin_degradative_pathway" YHL017W None None biological_process_unknown molecular_function_unknown clathrin-coated_vesicle None None 8 70273 71871 YHL017W S000001009 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_co-localizes_with_clathrin-coated_vesicles YHL018W None None biological_process_unknown molecular_function_unknown mitochondrion None None 8 69705 70067 YHL018W S000001010 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_mitochondria_and_is_induced_in_response_to_the_DNA-damaging_agent_MMS YHL019C APM2 None vesicle-mediated_transport clathrin_binding AP-1_adaptor_complex None None 8 69545 67728 YHL019C S000001011 "ORF,_Verified" "Protein_of_unknown_function,_homologous_to_the_medium_chain_of_mammalian_clathrin-associated_protein_complex;_involved_in_vesicular_transport" YHL021C None FMP12 biological_process_unknown molecular_function_unknown mitochondrion None None 8 65856 64459 YHL021C S000001013 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_null_mutant_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation)" YHL022C SPO11 None meiotic_DNA_double-strand_break_formation "endodeoxyribonuclease_activity,_producing_3'-phosphomonoesters" nuclear_chromosome None None 8 64155 62959 YHL022C S000001014 "ORF,_Verified" Meiosis-specific_protein_that_initiates_meiotic_recombination_by_catalyzing_the_formation_of_double-strand_breaks_in_DNA_via_a_transesterification_reaction;_required_for_homologous_chromosome_pairing_and_synaptonemal_complex_formation YHL023C RMD11 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 62561 59121 YHL023C S000001015 "ORF,_Verified" Protein_required_for_meiosis YHL024W RIM4 None meiosis* RNA_binding cytoplasm None None 8 56647 58788 YHL024W S000001016 "ORF,_Verified" Putative_RNA-binding_protein_required_for_the_expression_of_early_and_middle_sporulation_genes YHL025W SNF6 None chromatin_remodeling general_RNA_polymerase_II_transcription_factor_activity SWI/SNF_complex* None None 8 54849 55847 YHL025W S000001017 "ORF,_Verified" Subunit_of_the_SWI/SNF_chromatin_remodeling_complex_involved_in_transcriptional_regulation;_functions_interdependently_in_transcriptional_activation_with_Snf2p_and_Snf5p YHL026C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G2/M None 8 54164 53217 YHL026C S000001018 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YHL026C_is_not_an_essential_gene;_in_2005_the_start_site_was_moved_141_nt_upstream_(see_Locus_History) YHL028W WSC4 YFW1|YHC8 response_to_stress* transmembrane_receptor_activity endoplasmic_reticulum_membrane* G2/M None 8 48761 50578 YHL028W S000001020 "ORF,_Verified" ER_membrane_protein_involved_in_the_translocation_of_soluble_secretory_proteins_and_insertion_of_membrane_proteins_into_the_ER_membrane;_may_also_have_a_role_in_the_stress_response_but_has_only_partial_functional_overlap_with_WSC1-3 YHL029C None None metabolism molecular_function_unknown cytoplasm None None 8 47966 45927 YHL029C S000001021 "ORF,_Uncharacterized" "Cytoplasmic_protein_required_for_replication_of_Brome_mosaic_virus_in_S._cerevisiae,_which_is_a_model_system_for_studying_replication_of_positive-strand_RNA_viruses_in_their_natural_hosts" YHL031C GOS1 None vesicle_fusion* v-SNARE_activity integral_to_membrane None None 8 39484 38813 YHL031C S000001023 "ORF,_Verified" "v-SNARE_protein_involved_in_Golgi_transport,_homolog_of_the_mammalian_protein_GOS-28/GS28" YHL032C GUT1 None glycerol_metabolism glycerol_kinase_activity cytoplasm None None 8 38506 36377 YHL032C S000001024 "ORF,_Verified" "Glycerol_kinase,_converts_glycerol_to_glycerol-3-phosphate;_glucose_repression_of_expression_is_mediated_by_Adr1p_and_Ino2p-Ino4p;_derepression_of_expression_on_non-fermentable_carbon_sources_is_mediated_by_Opi1p_and_Rsf1p" YHL033C RPL8A MAK7 protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 8 36023 35253 YHL033C S000001025 "ORF,_Verified" "Ribosomal_protein_L4_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl8Bp_and_has_similarity_to_rat_L7a_ribosomal_protein;_mutation_results_in_decreased_amounts_of_free_60S_subunits" YHL035C VMR1 None transport "ATPase_activity,_coupled_to_transmembrane_movement_of_substances" mitochondrion* None None 8 32754 27976 YHL035C S000001027 "ORF,_Verified" "Protein_of_unknown_function_that_may_interact_with_ribosomes,_based_on_co-purification_experiments;_member_of_the_ATP-binding_cassette_(ABC)_family;_potential_Cdc28p_substrate;_detected_in_purified_mitochondria_in_high-throughput_studies" YHL036W MUP3 None amino_acid_transport L-methionine_transporter_activity membrane None None 8 26239 27879 YHL036W S000001028 "ORF,_Verified" "Low_affinity_methionine_permease,_similar_to_Mup1p" YHL038C CBP2 None Group_I_intron_splicing "RNA_splicing_factor_activity,_transesterification_mechanism" mitochondrion None Up 8 25506 23614 YHL038C S000001030 "ORF,_Verified" "Mitochondrial_protein_required_for_splicing_of_the_group_I_intron_aI5_of_the_COB_pre-mRNA,_binds_to_the_RNA_to_promote_splicing;_also_involved_in_but_not_essential_for_splicing_of_the_COB_bI2_intron_and_the_intron_in_the_21S_rRNA_gene" YHL039W None None biological_process_unknown molecular_function_unknown cytoplasm None None 8 21780 23537 YHL039W S000001031 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YHL042W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 15665 16117 YHL042W S000001034 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_member_of_the_DUP380_subfamily_of_conserved,_often_subtelomerically-encoded_proteins" YHL043W ECM34 None cell_wall_organization_and_biogenesis molecular_function_unknown cellular_component_unknown None None 8 14899 15411 YHL043W S000001035 "ORF,_Verified" "Putative_protein_of_unknown_function;_member_of_the_DUP380_subfamily_of_conserved,_often_subtelomerically-encoded_proteins" YHL044W None None biological_process_unknown molecular_function_unknown plasma_membrane None None 8 13563 14270 YHL044W S000001036 "ORF,_Uncharacterized" "Putative_integral_membrane_protein,_member_of_DUP240_gene_family;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_plasma_membrane_in_a_punctate_pattern" YHL047C ARN2 TAF1 iron_ion_homeostasis* siderophore-iron_transporter_activity plasma_membrane* None None 8 10211 8298 YHL047C S000001039 "ORF,_Verified" "Transporter,_member_of_the_ARN_family_of_transporters_that_specifically_recognize_siderophore-iron_chelates;_responsible_for_uptake_of_iron_bound_to_the_siderophore_triacetylfusarinine_C" YHL048W COS8 None response_to_unfolded_protein molecular_function_unknown nuclear_envelope None None 8 6400 7545 YHL048W S000001040 "ORF,_Verified" "Nuclear_membrane_protein,_member_of_the_DUP380_subfamily_of_conserved,_often_subtelomerically-encoded_proteins;_regulation_suggests_a_potential_role_in_the_unfolded_protein_response" YHL049C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 8 4540 3725 YHL049C S000001041 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YHL050C None None biological_process_unknown helicase_activity cellular_component_unknown G1 None 8 3310 445 YHL050C S000001042 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_potential_Cdc28p_substrate" YHR001W OSH7 None steroid_biosynthesis oxysterol_binding cellular_component_unknown None None 8 106050 107363 YHR001W S000001043 "ORF,_Verified" "Member_of_an_oxysterol-binding_protein_family_with_seven_members_in_S._cerevisiae;_family_members_have_overlapping,_redundant_functions_in_sterol_metabolism_and_collectively_perform_a_function_essential_for_viability" YHR001W-A QCR10 None aerobic_respiration* ubiquinol-cytochrome-c_reductase_activity mitochondrion* None None 8 107821 108117 YHR001W-A S000003529 "ORF,_Verified" "Subunit_of_the_ubiqunol-cytochrome_c_oxidoreductase_complex_which_includes_Cobp,_Rip1p,_Cyt1p,_Cor1p,_Qcr2p,_Qcr6p,_Qcr7p,_Qcr8p,_Qcr9p,_and_Qcr10p_and_comprises_part_of_the_mitochondrial_respiratory_chain" YHR002W LEU5 None coenzyme_A_transport coenzyme_A_transporter_activity mitochondrial_inner_membrane None None 8 108807 109880 YHR002W S000001044 "ORF,_Verified" "Mitochondrial_carrier_protein_involved_in_the_accumulation_of_CoA_in_the_mitochondrial_matrix;_homolog_of_human_Graves_disease_protein;_does_not_encode_an_isozyme_of_Leu4p,_as_first_hypothesized" YHR004C NEM1 None sporulation_(sensu_Fungi)* molecular_function_unknown mitochondrion* None None 8 113089 111749 YHR004C S000001046 "ORF,_Verified" "Catalytic_subunit_of_Nem1p-Spo7p_phosphatase_holoenzyme,_which_regulates_nuclear_growth_by_controlling_recruitment_of_Pah1p_onto_promoters_of_phospholipid_biosynthetic_genes;_required_for_normal_nuclear_envelope_morphology_and_sporulation" YHR005C GPA1 SCG1|DAC1|CDC70 signal_transduction_during_conjugation_with_cellular_fusion GTPase_activity plasma_membrane* M/G1 Up 8 114912 113494 YHR005C S000001047 "ORF,_Verified" GTP-binding_alpha_subunit_of_the_heterotrimeric_G_protein_that_couples_to_pheromone_receptors;_negatively_regulates_the_mating_pathway_by_sequestering_G(beta)gamma_and_by_triggering_an_adaptive_response;_activates_Vps34p_at_the_endosome YHR005C-A MRS11 TIM10 protein_import_into_mitochondrial_inner_membrane unfolded_protein_binding* mitochondrial_intermembrane_space* None None 8 115896 115615 YHR005C-A S000003530 "ORF,_Verified" "Essential_protein_of_the_mitochondrial_intermembrane_space,_forms_a_complex_with_Tim9p_(TIM10_complex)_that_mediates_insertion_of_hydrophobic_proteins_at_the_inner_membrane,_has_homology_to_Mrs5p,_which_is_also_involved_in_this_process" YHR006W STP2 None positive_regulation_of_transcription_from_RNA_polymerase_II_promoter specific_RNA_polymerase_II_transcription_factor_activity nucleus S/G2 None 8 117809 119434 YHR006W S000001048 "ORF,_Verified" "Transcription_factor,_activated_by_proteolytic_processing_in_response_to_signals_from_the_SPS_sensor_system_for_external_amino_acids;_activates_transcription_of_amino_acid_permease_genes" YHR007C ERG11 CYP51 ergosterol_biosynthesis sterol_14-demethylase_activity endoplasmic_reticulum None None 8 121678 120086 YHR007C S000001049 "ORF,_Verified" "Lanosterol_14-alpha-demethylase,_catalyzes_the_C-14_demethylation_of_lanosterol_to_form_4,4''-dimethyl_cholesta-8,14,24-triene-3-beta-ol_in_the_ergosterol_biosynthesis_pathway;_member_of_the_cytochrome_P450_family" YHR008C SOD2 None replicative_cell_aging* manganese_superoxide_dismutase_activity mitochondrion* None None 8 123585 122884 YHR008C S000001050 "ORF,_Verified" "Mitochondrial_superoxide_dismutase,_protects_cells_against_oxygen_toxicity;_phosphorylated" YHR009C None None biological_process_unknown molecular_function_unknown cytoplasm None None 8 125675 124104 YHR009C S000001051 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_not_an_essential_gene YHR010W RPL27A RPL27 protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 8 126515 127486 YHR010W S000001052 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl27Bp_and_has_similarity_to_rat_L27_ribosomal_protein" YHR011W DIA4 None aerobic_respiration* serine-tRNA_ligase_activity cytoplasm* None None 8 127774 129114 YHR011W S000001053 "ORF,_Verified" "Probable_mitochondrial_seryl-tRNA_synthetase,_mutant_displays_increased_invasive_and_pseudohyphal_growth" YHR012W VPS29 PEP11 "retrograde_transport,_endosome_to_Golgi" molecular_function_unknown endosome* None None 8 129475 130442 YHR012W S000001054 "ORF,_Verified" Endosomal_protein_that_is_a_subunit_of_the_membrane-associated_retromer_complex_essential_for_endosome-to-Golgi_retrograde_transport;_forms_a_subcomplex_with_Vps35p_and_Vps26p_that_selects_cargo_proteins_for_endosome-to-Golgi_retrieval YHR014W SPO13 None positive_regulation_of_sister_chromatid_cohesion* protein_binding nucleus* None None 8 132040 132915 YHR014W S000001056 "ORF,_Verified" "Meiosis-specific_protein,_involved_in_maintaining_sister_chromatid_cohesion_during_meiosis_I_as_well_as_promoting_proper_attachment_of_kinetochores_to_the_spindle_during_meiosis_I_and_meiosis_II" YHR015W MIP6 None mRNA_export_from_nucleus RNA_binding nuclear_pore None None 8 134547 136526 YHR015W S000001057 "ORF,_Verified" "Putative_RNA-binding_protein,_interacts_with_Mex67p,_which_is_a_component_of_the_nuclear_pore_involved_in_nuclear_mRNA_export" YHR016C YSC84 LSB4 endocytosis* molecular_function_unknown actin_cortical_patch None Up 8 138448 136874 YHR016C S000001058 "ORF,_Verified" Protein_involved_in_the_organization_of_the_actin_cytoskeleton;_contains_SH3_domain_similar_to_Rvs167p YHR017W YSC83 None biological_process_unknown molecular_function_unknown mitochondrion None None 8 138687 139844 YHR017W S000001059 "ORF,_Verified" "Non-essential_mitochondrial_protein_of_unknown_function;_mRNA_induced_during_meiosis,_peaking_between_mid_to_late_prophase_of_meiosis_I;_similar_to_S._douglasii_YSD83" YHR018C ARG4 None arginine_biosynthesis argininosuccinate_lyase_activity cytosol None Up 8 141395 140004 YHR018C S000001060 "ORF,_Verified" "Argininosuccinate_lyase,_catalyzes_the_final_step_in_the_arginine_biosynthesis_pathway" YHR020W None None tRNA_aminoacylation_for_protein_translation proline-tRNA_ligase_activity cellular_component_unknown None None 8 143989 146055 YHR020W S000001062 "ORF,_Verified" "Protein_of_unknown_function_that_may_interact_with_ribosomes,_based_on_co-purification_experiments;_has_similarity_to_proline-tRNA_ligase;_YHR020W_is_an_essential_gene" YHR021C RPS27B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 8 148662 147864 YHR021C S000001063 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps27Ap_and_has_similarity_to_rat_S27_ribosomal_protein YHR021W-A ECM12 None cell_wall_organization_and_biogenesis molecular_function_unknown cellular_component_unknown None None 8 149218 149673 YHR021W-A S000003531 "ORF,_Uncharacterized" Non-essential_protein_of_unknown_function YHR022C None None biological_process_unknown molecular_function_unknown cellular_component_unknown M/G1 None 8 150338 149568 YHR022C S000001064 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YHR022C_is_not_an_essential_gene. YHR023W MYO1 None response_to_osmotic_stress* microfilament_motor_activity contractile_ring_(sensu_Saccharomyces) G2/M None 8 151659 157445 YHR023W S000001065 "ORF,_Verified" "Type_II_myosin_heavy_chain,_required_for_wild-type_cytokinesis_and_cell_separation;_localizes_to_the_actomyosin_ring;_binds_to_myosin_light_chains_Mlc1p_and_Mlc2p_through_its_IQ1_and_IQ2_motifs_respectively" YHR024C MAS2 MIF2 mitochondrial_protein_processing mitochondrial_processing_peptidase_activity mitochondrial_processing_peptidase_complex None None 8 159185 157737 YHR024C S000001066 "ORF,_Verified" "Larger_subunit_of_the_mitochondrial_processing_protease_(MPP),_essential_processing_enzyme_that_cleaves_the_N-terminal_targeting_sequences_from_mitochondrially_imported_proteins" YHR025W THR1 None methionine_metabolism* homoserine_kinase_activity cellular_component_unknown None None 8 159431 160504 YHR025W S000001067 "ORF,_Verified" "Homoserine_kinase,_conserved_protein_required_for_threonine_biosynthesis;_expression_is_regulated_by_the_GCN4-mediated_general_amino_acid_control_pathway" YHR026W PPA1 VMA16 vacuolar_acidification "hydrogen-transporting_ATPase_activity,_rotational_mechanism" integral_to_membrane* None None 8 160837 161478 YHR026W S000001068 "ORF,_Verified" "Subunit_c''_of_the_vacuolar_ATPase,_which_functions_in_acidification_of_the_vacuole;_one_of_three_proteolipid_subunits_of_the_V0_domain" YHR027C RPN1 NAS1|HRD2 ubiquitin-dependent_protein_catabolism endopeptidase_activity* cytoplasm* None Up 8 164704 161723 YHR027C S000001069 "ORF,_Verified" "Non-ATPase_base_subunit_of_the_19S_regulatory_particle_of_the_26S_proteasome;_may_participate_in_the_recognition_of_several_ligands_of_the_proteasome;_contains_a_leucine-rich_repeat_(LRR)_domain,_a_site_for_protein?protein_interactions" YHR029C YHI9 None biological_process_unknown molecular_function_unknown cellular_component_unknown G2/M Up 8 168554 167670 YHR029C S000001071 "ORF,_Verified" "Protein_of_unknown_function;_null_mutant_is_defective_in_unfolded_protein_response;_possibly_involved_in_a_membrane_regulation_metabolic_pathway;_member_of_the_PhzF_superfamily,_though_most_likely_not_involved_in_phenazine_production" YHR030C SLT2 SLK2|MPK1|BYC2 cell_wall_organization_and_biogenesis* MAP_kinase_activity cytoplasm* S None 8 170337 168883 YHR030C S000001072 "ORF,_Verified" Serine/threonine_MAP_kinase_involved_in_regulating_the_maintenance_of_cell_wall_integrity_and_progression_through_the_cell_cycle;_regulated_by_the_PKC1-mediated_signaling_pathway YHR031C RRM3 RTT104 mitochondrial_genome_maintenance* DNA_helicase_activity* nuclear_telomeric_heterochromatin None None 8 172963 170792 YHR031C S000001073 "ORF,_Verified" DNA_helicase_involved_in_rDNA_replication_and_Ty1_transposition;_relieves_replication_fork_pauses_at_telomeric_regions;_structurally_and_functionally_related_to_Pif1p YHR032W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 173337 175082 YHR032W S000001074 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_putative_substrate_of_the_cAMP-dependent_protein_kinase_(PKA) YHR033W None None biological_process_unknown molecular_function_unknown cytoplasm None None 8 175541 176812 YHR033W S000001075 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_epitope-tagged_protein_localizes_to_the_cytoplasm YHR035W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 178212 180104 YHR035W S000001077 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_not_an_essential_gene YHR037W PUT2 None glutamate_biosynthesis* 1-pyrroline-5-carboxylate_dehydrogenase_activity mitochondrion None Up 8 181970 183697 YHR037W S000001079 "ORF,_Verified" "Delta-1-pyrroline-5-carboxylate_dehydrogenase,_nuclear-encoded_mitochondrial_protein_involved_in_utilization_of_proline_as_sole_nitrogen_source;_deficiency_of_the_human_homolog_causes_HPII,_an_autosomal_recessive_inborn_error_of_metabolism" YHR038W RRF1 FIL1|KIM4 protein_biosynthesis translation_termination_factor_activity mitochondrion None None 8 184059 184751 YHR038W S000001080 "ORF,_Verified" "Mitochondrial_ribosome_recycling_factor,_essential_for_mitochondrial_protein_synthesis_and_for_the_maintenance_of_the_respiratory_function_of_mitochondria" YHR039C MSC7 None meiotic_recombination molecular_function_unknown endoplasmic_reticulum None None 8 186802 184868 YHR039C S000001081 "ORF,_Verified" "Protein_of_unknown_function,_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_endoplasmic_reticulum;_msc7_mutants_are_defective_in_directing_meiotic_recombination_events_to_homologous_chromatids" YHR042W NCP1 CPR1 ergosterol_biosynthesis electron_transporter_activity mitochondrion* None None 8 190536 192611 YHR042W S000001084 "ORF,_Verified" NADP-cytochrome_P450_reductase;_involved_in_ergosterol_biosynthesis;_associated_and_coordinately_regulated_with_Erg11p YHR043C DOG2 None response_to_stress* 2-deoxyglucose-6-phosphatase_activity cytoplasm* None None 8 193538 192798 YHR043C S000001085 "ORF,_Verified" "2-deoxyglucose-6-phosphate_phosphatase,_member_of_a_family_of_low_molecular_weight_phosphatases,_similar_to_Dog1p,_induced_by_oxidative_and_osmotic_stress,_confers_2-deoxyglucose_resistance_when_overexpressed" YHR045W None None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 8 195544 197226 YHR045W S000001087 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_endoplasmic_reticulum YHR047C AAP1 AAP1' proteolysis* aminopeptidase_activity cytoplasm* None None 8 201303 198733 YHR047C S000001089 "ORF,_Verified" "Arginine/alanine_aminopeptidase,_overproduction_stimulates_glycogen_accumulation" YHR048W YHK8 None drug_transport drug_transporter_activity integral_to_membrane None None 8 204600 206144 YHR048W S000001090 "ORF,_Uncharacterized" Presumed_antiporter_of_the_DHA1_family_of_multidrug_resistance_transporters;_contains_12_predicted_transmembrane_spans;_expression_of_gene_is_up-regulated_in_cells_exhibiting_reduced_susceptibility_to_azoles YHR049W FSH1 None biological_process_unknown serine_hydrolase_activity cytoplasm* None None 8 206455 207186 YHR049W S000001091 "ORF,_Verified" Serine_hydrolase_that_localizes_to_both_the_nucleus_and_cytoplasm;_sequence_is_similar_to_Fsh2p_and_Fsh3p YHR051W COX6 None aerobic_respiration* cytochrome-c_oxidase_activity respiratory_chain_complex_IV_(sensu_Eukaryota) None None 8 209699 210145 YHR051W S000001093 "ORF,_Verified" "Subunit_VI_of_cytochrome_c_oxidase,_which_is_the_terminal_member_of_the_mitochondrial_inner_membrane_electron_transport_chain;_expression_is_regulated_by_oxygen_levels" YHR052W CIC1 NSA3 ribosomal_large_subunit_biogenesis* "protein_binding,_bridging" nucleolus* None None 8 210842 211972 YHR052W S000001094 "ORF,_Verified" Essential_protein_that_interacts_with_proteasome_components_and_has_a_potential_role_in_proteasome_substrate_specificity;_also_copurifies_with_66S_pre-ribosomal_particles YHR053C CUP1-1 CUP1 response_to_copper_ion copper_ion_binding cytosol None None 8 212722 212537 YHR053C S000001095 "ORF,_Verified" "Metallothionein,_binds_copper_and_mediates_resistance_to_high_concentrations_of_copper_and_cadmium;_locus_is_variably_amplified_in_different_strains,_with_two_copies,_CUP1-1_and_CUP1-2,_in_the_genomic_sequence_reference_strain_S288C" YHR054C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 214251 213187 YHR054C S000001096 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YHR055C CUP1-2 CUP1 response_to_copper_ion copper_ion_binding cytosol None None 8 214720 214535 YHR055C S000001097 "ORF,_Verified" "Metallothionein,_binds_copper_and_mediates_resistance_to_high_concentrations_of_copper_and_cadmium;_locus_is_variably_amplified_in_different_strains,_with_two_copies,_CUP1-1_and_CUP1-2,_in_the_genomic_sequence_reference_strain_S288C" YHR057C CPR2 CYP2 biological_process_unknown peptidyl-prolyl_cis-trans_isomerase_activity cellular_component_unknown None None 8 218845 218228 YHR057C S000001099 "ORF,_Verified" "Peptidyl-prolyl_cis-trans_isomerase_(cyclophilin),_catalyzes_the_cis-trans_isomerization_of_peptide_bonds_N-terminal_to_proline_residues;_has_a_potential_role_in_the_secretory_pathway" YHR058C MED6 None transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_mediator_activity mediator_complex None None 8 219886 218999 YHR058C S000001100 "ORF,_Verified" Subunit_of_the_RNA_polymerase_II_mediator_complex;_associates_with_core_polymerase_subunits_to_form_the_RNA_polymerase_II_holoenzyme;_essential_for_transcriptional_regulation YHR059W FYV4 None biological_process_unknown molecular_function_unknown mitochondrion None None 8 220110 220502 YHR059W S000001101 "ORF,_Verified" "Protein_of_unknown_function,_required_for_survival_upon_exposure_to_K1_killer_toxin" YHR060W VMA22 VPH6|CEV1 protein_complex_assembly* unfolded_protein_binding endoplasmic_reticulum_membrane None None 8 220727 221272 YHR060W S000001102 "ORF,_Verified" "Peripheral_membrane_protein_that_is_required_for_vacuolar_H+-ATPase_(V-ATPase)_function,_although_not_an_actual_component_of_the_V-ATPase_complex;_functions_in_the_assembly_of_the_V-ATPase;_localized_to_the_yeast_endoplasmic_reticulum_(ER)" YHR062C RPP1 None rRNA_processing* ribonuclease_P_activity* ribonuclease_MRP_complex* None None 8 223760 222879 YHR062C S000001104 "ORF,_Verified" "Subunit_of_both_RNase_MRP,_which_cleaves_pre-rRNA,_and_nuclear_RNase_P,_which_cleaves_tRNA_precursors_to_generate_mature_5'_ends" YHR063C PAN5 None pantothenate_biosynthesis 2-dehydropantoate_2-reductase_activity cytoplasm* None None 8 225171 224032 YHR063C S000001105 "ORF,_Verified" "2-dehydropantoate_2-reductase,_part_of_the_pantothenic_acid_pathway,_structurally_homologous_to_E._coli_panE" YHR064C SSZ1 PDR13 protein_biosynthesis unfolded_protein_binding cytoplasm None None 8 227143 225527 YHR064C S000001106 "ORF,_Verified" Hsp70_protein_that_interacts_with_Zuo1p_(a_DnaJ_homolog)_to_form_a_ribosome-associated_complex_that_binds_the_ribosome_via_the_Zuo1p_subunit;_also_involved_in_pleiotropic_drug_resistance_via_sequential_activation_of_PDR1_and_PDR5;_binds_ATP YHR065C RRP3 None 35S_primary_transcript_processing ATP-dependent_RNA_helicase_activity nucleolus None None 8 229039 227534 YHR065C S000001107 "ORF,_Verified" "Protein_involved_in_rRNA_processing;_required_for_maturation_of_the_35S_primary_transcript_of_pre-rRNA_and_for_cleavage_leading_to_mature_18S_rRNA;_homologous_to_eIF-4a,_which_is_a_DEAD_box_RNA-dependent_ATPase_with_helicase_activity" YHR066W SSF1 None ribosomal_large_subunit_assembly_and_maintenance* rRNA_binding nucleolus None None 8 229337 230698 YHR066W S000001108 "ORF,_Verified" "Constituent_of_66S_pre-ribosomal_particles,_required_for_ribosomal_large_subunit_maturation;_functionally_redundant_with_Ssf2p;_member_of_the_Brix_family" YHR067W HTD2 RMD12 fatty_acid_biosynthesis 3-hydroxyacyl-[acyl-carrier_protein]_dehydratase_activity mitochondrion G1 None 8 230972 231814 YHR067W S000001109 "ORF,_Verified" "Mitochondrial_3-hydroxyacyl-thioester_dehydratase_involved_in_fatty_acid_biosynthesis,_required_for_respiratory_growth_and_for_normal_mitochondrial_morphology" YHR068W DYS1 None hypusine_biosynthesis_from_peptidyl-lysine "transferase_activity,_transferring_alkyl_or_aryl_(other_than_methyl)_groups" cytoplasm None None 8 232135 233298 YHR068W S000001110 "ORF,_Verified" "Deoxyhypusine_synthase,_catalyzes_formation_of_deoxyhypusine,_the_first_step_in_hypusine_biosynthesis;_triggers_posttranslational_hypusination_of_translation_elongation_factor_eIF-5A_and_regulates_its_intracellular_levels;_tetrameric" YHR069C RRP4 None 35S_primary_transcript_processing* 3'-5'-exoribonuclease_activity nuclear_exosome_(RNase_complex)* None None 8 234660 233581 YHR069C S000001111 "ORF,_Verified" Exosome_non-catalytic_core_component;_involved_in_3'-5'_exoribonuclease_processing_of_rRNA_and_mRNA YHR070W TRM5 None tRNA_methylation tRNA_(guanine)_methyltransferase_activity cytoplasm* None None 8 234883 236382 YHR070W S000001112 "ORF,_Verified" "tRNA(m(1)G37)methyltransferase,_methylates_a_tRNA_base_adjacent_to_the_anticodon_that_has_a_role_in_prevention_of_frameshifting;_highly_conserved_across_Archaea,_Bacteria,_and_Eukarya" YHR071W PCL5 None cell_cycle cyclin-dependent_protein_kinase_regulator_activity cyclin-dependent_protein_kinase_holoenzyme_complex None Up 8 237006 237695 YHR071W S000001113 "ORF,_Verified" "Cyclin,_interacts_with_Pho85p_cyclin-dependent_kinase_(Cdk),_induced_by_Gcn4p_at_level_of_transcription,_specifically_required_for_Gcn4p_degradation,_may_be_sensor_of_cellular_protein_biosynthetic_capacity" YHR072W ERG7 None ergosterol_biosynthesis lanosterol_synthase_activity endoplasmic_reticulum* None None 8 239100 241295 YHR072W S000001114 "ORF,_Verified" "Lanosterol_synthase,_an_essential_enzyme_that_catalyzes_the_cyclization_of_squalene_2,3-epoxide,_a_step_in_ergosterol_biosynthesis" YHR072W-A NOP10 None rRNA_modification* RNA_binding small_nucleolar_ribonucleoprotein_complex None None 8 241666 241842 YHR072W-A S000007455 "ORF,_Verified" "Constituent_of_small_nucleolar_ribonucleoprotein_particles_containing_H/ACA-type_snoRNAs,_which_are_required_for_pseudouridylation_and_processing_of_pre-18S_rRNA" YHR073W OSH3 None steroid_biosynthesis oxysterol_binding cytoplasm None None 8 242584 245574 YHR073W S000001115 "ORF,_Verified" "Member_of_an_oxysterol-binding_protein_family_with_seven_members_in_S._cerevisiae;_family_members_have_overlapping,_redundant_functions_in_sterol_metabolism_and_collectively_perform_a_function_essential_for_viability" YHR074W QNS1 None NAD_biosynthesis "hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds,_in_linear_amides*" cytoplasm* None Up 8 246195 248339 YHR074W S000001116 "ORF,_Verified" "Glutamine-dependent_NAD(+)_synthetase,_essential_for_the_formation_of_NAD(+)_from_nicotinic_acid_adenine_dinucleotide" YHR075C PPE1 MRPS2 protein_biosynthesis* structural_constituent_of_ribosome* mitochondrial_small_ribosomal_subunit None None 8 249643 248441 YHR075C S000001117 "ORF,_Verified" Protein_with_carboxyl_methyl_esterase_activity_that_may_have_a_role_in_demethylation_of_the_phosphoprotein_phosphatase_catalytic_subunit;_also_identified_as_a_small_subunit_mitochondrial_ribosomal_protein YHR076W PTC7 None biological_process_unknown protein_phosphatase_type_2C_activity mitochondrion None None 8 251103 252227 YHR076W S000001118 "ORF,_Verified" Mitochondrially_localized_type_2C_protein_phosphatase;_expression_induced_by_growth_on_ethanol_and_by_sustained_osmotic_stress;_possible_role_in_carbon_source_utilization_in_low_oxygen_environments YHR077C NMD2 UPF2|SUA1|IFS1 mRNA_catabolism* protein_binding cytoplasm* None None 8 255758 252376 YHR077C S000001119 "ORF,_Verified" Protein_involved_in_the_nonsense-mediated_mRNA_decay_(NMD)_pathway;_interacts_with_Nam7p_and_Upf3p;_involved_in_telomere_maintenance YHR078W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 256362 258020 YHR078W S000001120 "ORF,_Uncharacterized" High_osmolarity-regulated_gene_of_unknown_function YHR081W LRP1 RRP47|YC1D DNA_repair* molecular_function_unknown nuclear_exosome_(RNase_complex) None None 8 267540 268094 YHR081W S000001123 "ORF,_Verified" Substrate-specific_nuclear_cofactor_for_exosome_activity_in_the_processing_of_stable_RNAs;_required_for_telomere_length_maintenance;_homolog_of_mammalian_nuclear_matrix_protein_C1D_involved_in_regulation_of_DNA_repair_and_recombination YHR088W RPF1 None ribosomal_large_subunit_assembly_and_maintenance* rRNA_primary_transcript_binding nucleolus None None 8 281497 282384 YHR088W S000001130 "ORF,_Verified" "Nucleolar_protein_involved_in_the_assembly_of_the_large_ribosomal_subunit;_constituent_of_66S_pre-ribosomal_particles;_contains_a_sigma(70)-like_motif,_which_is_thought_to_bind_RNA" YHR089C GAR1 None rRNA_modification* RNA_binding nucleolus* None Down 8 283300 282683 YHR089C S000001131 "ORF,_Verified" "Protein_component_of_the_H/ACA_snoRNP_pseudouridylase_complex,_involved_in_the_modification_and_cleavage_of_the_18S_pre-rRNA" YHR090C YNG2 EAF4|NBN1 chromatin_modification enzyme_activator_activity nucleus* None None 8 284627 283779 YHR090C S000001132 "ORF,_Verified" Subunit_of_the_NuA4_histone_acetyltransferase_complex_that_acetylates_histone_H4_and_H2A;_has_similarity_to_the_human_tumor_suppressor_ING1 YHR091C MSR1 None protein_biosynthesis* arginine-tRNA_ligase_activity mitochondrion None None 8 286772 284841 YHR091C S000001133 "ORF,_Verified" Mitochondrial_arginyl-tRNA_synthetase YHR096C HXT5 None hexose_transport glucose_transporter_activity* plasma_membrane None None 8 296450 294672 YHR096C S000001138 "ORF,_Verified" "Hexose_transporter_with_moderate_affinity_for_glucose,_induced_in_the_presence_of_non-fermentable_carbon_sources,_induced_by_a_decrease_in_growth_rate,_contains_an_extended_N-terminal_domain_relative_to_other_HXTs" YHR097C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 8 298612 297388 YHR097C S000001139 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_the_nucleus YHR098C SFB3 LST1 ER_to_Golgi_transport molecular_function_unknown endoplasmic_reticulum* S None 8 301937 299148 YHR098C S000001140 "ORF,_Verified" "Member_of_the_Sec24p_family;_forms_a_complex,_with_Sec23p,_that_is_involved_in_sorting_of_Pma1p_into_COPII_vesicles;_peripheral_ER_membrane_protein;_potential_Cdc28p_substrate" YHR099W TRA1 None regulation_of_transcription_from_RNA_polymerase_II_promoter* histone_acetyltransferase_activity histone_acetyltransferase_complex* None None 8 302764 313998 YHR099W S000001141 "ORF,_Verified" "Subunit_of_SAGA_and_NuA4_histone_acetyltransferase_complexes;_interacts_with_acidic_activators_(e.g.,_Gal4p)_which_leads_to_transcription_activation;_similar_to_human_TRRAP,_which_is_a_cofactor_for_c-Myc_mediated_oncogenic_transformation" YHR100C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 314676 314119 YHR100C S000001142 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_required_for_respiratory_growth;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YHR101C BIG1 None cell_wall_biosynthesis_(sensu_Fungi) molecular_function_unknown integral_to_endoplasmic_reticulum_membrane None None 8 315971 314877 YHR101C S000001143 "ORF,_Verified" "Integral_membrane_protein_of_the_endoplasmic_reticulum,_required_for_normal_content_of_cell_wall_beta-1,6-glucan" YHR102W KIC1 NRK1 cell_wall_organization_and_biogenesis* kinase_activity cytoplasm* None None 8 316575 319817 YHR102W S000001144 "ORF,_Verified" "Protein_kinase_of_the_PAK/Ste20_kinase_family,_required_for_cell_integrity_possibly_through_regulating_1,6-beta-glucan_levels_in_the_wall;_physically_interacts_with_Cdc31p_(centrin),_which_is_a_component_of_the_spindle_pole_body" YHR103W SBE22 None cell_wall_organization_and_biogenesis molecular_function_unknown cytoplasm None None 8 320417 322975 YHR103W S000001145 "ORF,_Verified" Protein_involved_in_the_transport_of_cell_wall_components_from_the_Golgi_to_the_cell_surface;_similar_in_structure_and_functionally_redundant_with_Sbe2p;_involved_in_bud_growth YHR104W GRE3 None response_to_stress* aldo-keto_reductase_activity* cytoplasm* None None 8 323412 324395 YHR104W S000001146 "ORF,_Verified" "Aldose_reductase_involved_in_methylglyoxal,_d-xylose_and_arabinose_metabolism;_stress_induced_(osmotic,_ionic,_oxidative,_heat_shock,_starvation_and_heavy_metals);_regulated_by_the_HOG_pathway" YHR105W YPT35 None biological_process_unknown molecular_function_unknown endosome None None 8 324769 325413 YHR105W S000001147 "ORF,_Verified" Endosomal_protein_of_unknown_function_that_contains_a_phox_(PX)_homology_domain_and_binds_to_both_phosphatidylinositol-3-phosphate_(PtdIns(3)P)_and_proteins_involved_in_ER-Golgi_or_vesicular_transport YHR106W TRR2 None response_to_oxidative_stress thioredoxin-disulfide_reductase_activity mitochondrion G1 None 8 325601 326629 YHR106W S000001148 "ORF,_Verified" "Mitochondrial_thioredoxin_reductase_involved_in_protection_against_oxidative_stress,_required_with_Glr1p_to_maintain_the_redox_state_of_Trx3p;_contains_active-site_motif_(CAVC)_present_in_prokaryotic_orthologs;_binds_NADPH_and_FAD" YHR107C CDC12 PSL7|CLA10 cell_wall_organization_and_biogenesis* GTPase_activity* cytoplasm* None None 8 328039 326816 YHR107C S000001149 "ORF,_Verified" "Component_of_the_septin_ring_of_the_mother-bud_neck_that_is_required_for_cytokinesis;_septins_recruit_proteins_to_the_neck_and_can_act_as_a_barrier_to_diffusion_at_the_membrane,_and_they_comprise_the_10nm_filaments_seen_with_EM" YHR108W GGA2 None Golgi_to_vacuole_transport* ubiquitin_binding Golgi_trans_face S/G2 None 8 328306 330063 YHR108W S000001150 "ORF,_Verified" "Golgi-localized_protein_with_homology_to_gamma-adaptin,_interacts_with_and_regulates_Arf1p_and_Arf2p_in_a_GTP-dependent_manner_in_order_to_facilitate_traffic_through_the_late_Golgi" YHR111W UBA4 YHR1 pseudohyphal_growth* URM1_activating_enzyme_activity cytoplasm None None 8 333075 334397 YHR111W S000001153 "ORF,_Verified" "Protein_that_activates_Urm1p_before_its_conjugation_to_proteins_(urmylation);_one_target_is_the_thioredoxin_peroxidase_Ahp1p,_suggesting_a_role_of_urmylation_in_the_oxidative_stress_response" YHR112C None None sulfur_metabolism cystathionine_beta-lyase_activity cytoplasm None None 8 335666 334530 YHR112C S000001154 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YHR113W None None proteolysis metalloendopeptidase_activity* cytoplasm* G1 None 8 336340 337812 YHR113W S000001155 "ORF,_Verified" Cytoplasmic_aspartyl_aminopeptidase;_cleaves_unblocked_N-terminal_acidic_amino_acid_residues_from_peptide_substrates;_forms_a_12_subunit_homo-oligomeric_complex;_M18_metalloprotease_family_member;_may_interact_with_ribosomes YHR114W BZZ1 LSB7 actin_filament_organization* molecular_function_unknown cytoplasm* None None 8 338086 339987 YHR114W S000001156 "ORF,_Verified" "SH3_domain_protein_implicated_in_the_regulation_of_actin_polymerization,_able_to_recruit_actin_polymerization_machinery_through_its_SH3_domains,_colocalizes_with_cortical_actin_patches_and_Las17p,_interacts_with_type_I_myosins" YHR115C DMA1 CHF1 mitotic_spindle_checkpoint* molecular_function_unknown cytoplasm None None 8 341362 340112 YHR115C S000001157 "ORF,_Verified" "Protein_involved_in_ubiquitin_ligation;_plays_a_role_in_regulating_spindle_position_and_orientation;_functionally_redundant_with_Dma2p;_orthologous_to_human_RNF8_protein,_also_has_sequence_similarity_to_human_Chfr." YHR116W COX23 None aerobic_respiration molecular_function_unknown cytoplasm* None None 8 341668 342123 YHR116W S000001158 "ORF,_Verified" "Mitochondrial_intermembrane_space_protein_that_functions_in_mitochondrial_copper_homeostasis,_essential_for_functional_cytochrome_oxidase_expression;_homologous_to_Cox17p" YHR117W TOM71 TOM72 biological_process_unknown protein_transporter_activity mitochondrial_outer_membrane None None 8 342352 344271 YHR117W S000001159 "ORF,_Verified" Mitochondrial_outer_membrane_protein_with_similarity_to_Tom70p;_probable_minor_component_of_the_TOM_(translocase_of_outer_membrane)_complex_responsible_for_recognition_and_import_of_mitochondrially_directed_proteins YHR118C ORC6 None DNA_replication_initiation* DNA_replication_origin_binding pre-replicative_complex* None None 8 345631 344324 YHR118C S000001160 "ORF,_Verified" "Subunit_of_the_origin_recognition_complex,_which_directs_DNA_replication_by_binding_to_replication_origins_and_is_also_involved_in_transcriptional_silencing;_phosphorylated_by_Cdc28p" YHR119W SET1 YTX1 chromatin_silencing_at_telomere* histone_lysine_N-methyltransferase_activity_(H3-K4_specific)* COMPASS_complex None None 8 346046 349288 YHR119W S000001161 "ORF,_Verified" "Histone_methyltransferase,_subunit_of_the_COMPASS_(Set1C)_complex_which_methylates_histone_H3_on_lysine_4;_required_in_transcriptional_silencing_near_telomeres_and_at_the_silent_mating_type_loci;_contains_a_SET_domain" YHR120W MSH1 None DNA_repair ATP_binding mitochondrion None None 8 349577 352456 YHR120W S000001162 "ORF,_Verified" "DNA-binding_protein_of_the_mitochondria_involved_in_repair_of_mitochondrial_DNA,_has_ATPase_activity_and_binds_to_DNA_mismatches;_has_homology_to_E._coli_MutS;_transcription_is_induced_during_meiosis" YHR123W EPT1 None phosphatidylethanolamine_biosynthesis ethanolaminephosphotransferase_activity endoplasmic_reticulum G1 None 8 354818 356084 YHR123W S000001165 "ORF,_Verified" "sn-1,2-diacylglycerol_ethanolamine-_and_cholinephosphotranferase;_not_essential_for_viability" YHR124W NDT80 None meiosis* transcription_factor_activity nuclear_chromosome None None 8 356564 358447 YHR124W S000001166 "ORF,_Verified" Meiosis-specific_transcription_factor_required_for_exit_from_pachytene_and_for_full_meiotic_recombination;_activates_middle_sporulation_genes;_competes_with_Sum1p_for_binding_to_promoters_containing_middle_sporulation_elements_(MSE) YHR127W None HSN1 biological_process_unknown molecular_function_unknown nucleus G1 None 8 360916 361647 YHR127W S000001169 "ORF,_Verified" Protein_of_unknown_function;_localizes_to_the_nucleus YHR128W FUR1 None pyrimidine_salvage uracil_phosphoribosyltransferase_activity intracellular None Down 8 362118 362768 YHR128W S000001170 "ORF,_Verified" "Uracil_phosphoribosyltransferase,_synthesizes_UMP_from_uracil;_involved_in_the_pyrimidine_salvage_pathway" YHR129C ARP1 ACT5 establishment_of_mitotic_spindle_orientation* structural_constituent_of_cytoskeleton dynactin_complex None None 8 364156 363002 YHR129C S000001171 "ORF,_Verified" Actin-related_protein_of_the_dynactin_complex;_required_for_spindle_orientation_and_nuclear_migration;_putative_ortholog_of_mammalian_centractin YHR131C None None biological_process_unknown molecular_function_unknown cytoplasm None None 8 367895 365343 YHR131C S000001173 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_overexpression_causes_a_cell_cycle_delay_or_arrest YHR132C ECM14 None cell_wall_organization_and_biogenesis* metalloendopeptidase_activity vacuole_(sensu_Fungi) None None 8 369797 368505 YHR132C S000001174 "ORF,_Verified" "Putative_metalloprotease_with_similarity_to_the_zinc_carboxypeptidase_family,_required_for_normal_cell_wall_assembly" YHR132W-A None None biological_process_unknown molecular_function_unknown cytoplasm* None None 8 370057 370452 YHR132W-A S000007496 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus YHR133C NSG1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 371600 370725 YHR133C S000001175 "ORF,_Verified" "Protein_involved_in_regulation_of_sterol_biosynthesis;_specifically_stabilizes_Hmg2p,_one_of_two_HMG-CoA_isoenzymes_that_catalyze_the_rate-limiting_step_in_sterol_biosynthesis;_homolog_of_mammalian_INSIG_proteins" YHR134W WSS1 None protein_sumoylation* molecular_function_unknown cellular_component_unknown None None 8 371752 372561 YHR134W S000001176 "ORF,_Verified" "Sumoylated_protein_of_unknown_function,_identified_based_on_genetic_interactions_with_SMT3;_UV-sensitive_mutant_phenotype_and_genetic_interactions_suggest_a_role_in_the_DNA_damage_response,_processing_stalled_or_collapsed_replication_forks" YHR135C YCK1 CKI2 protein_amino_acid_phosphorylation* casein_kinase_I_activity endoplasmic_reticulum* S/G2 None 8 374313 372697 YHR135C S000001177 "ORF,_Verified" "Palmitoylated,_plasma_membrane-bound_casein_kinase_I_isoform;_shares_redundant_functions_with_Yck2p_in_morphogenesis,_proper_septin_assembly,_endocytic_trafficking;_provides_an_essential_function_overlapping_with_that_of_Yck2p" YHR136C SPL2 None response_to_temperature_stimulus enzyme_inhibitor_activity cytoplasm None None 8 375103 374657 YHR136C S000001178 "ORF,_Verified" "Protein_with_similarity_to_cyclin-dependent_kinase_inhibitors,_overproduction_suppresses_a_plc1_null_mutation;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern" YHR137W ARO9 None aromatic_amino_acid_family_metabolism aromatic-amino-acid_transaminase_activity cytoplasm* G2/M Up 8 375712 377253 YHR137W S000001179 "ORF,_Verified" "Aromatic_aminotransferase_II,_catalyzes_the_first_step_of_tryptophan,_phenylalanine,_and_tyrosine_catabolism" YHR139C SPS100 None spore_wall_assembly_(sensu_Fungi) molecular_function_unknown spore_wall_(sensu_Fungi) None None 8 379202 378222 YHR139C S000001181 "ORF,_Verified" Protein_required_for_spore_wall_maturation;_expressed_during_sporulation;_may_be_a_component_of_the_spore_wall YHR140W None None biological_process_unknown molecular_function_unknown integral_to_membrane None None 8 380575 381294 YHR140W S000001182 "ORF,_Uncharacterized" Putative_integral_membrane_protein_of_unknown_function YHR141C RPL42B MAK18 protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 8 382754 381993 YHR141C S000001183 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_identical_to_Rpl42Ap_and_has_similarity_to_rat_L44;_required_for_propagation_of_the_killer_toxin-encoding_M1_double-stranded_RNA_satellite_of_the_L-A_double-stranded_RNA_virus" YHR142W CHS7 None ER_to_Golgi_transport* molecular_function_unknown endoplasmic_reticulum_membrane None None 8 383541 384491 YHR142W S000001184 "ORF,_Verified" "Protein_of_unknown_function,_involved_in_chitin_biosynthesis_by_regulating_Chs3p_export_from_the_ER" YHR143W DSE2 None cell_wall_organization_and_biogenesis* "glucan_1,3-beta-glucosidase_activity" cell_wall_(sensu_Fungi)* G1 None 8 385513 386490 YHR143W S000001186 "ORF,_Verified" "Daughter_cell-specific_secreted_protein_with_similarity_to_glucanases,_degrades_cell_wall_from_the_daughter_side_causing_daughter_to_separate_from_mother;_expression_is_repressed_by_cAMP" YHR143W-A RPC10 RPB12 transcription_from_RNA_polymerase_II_promoter* DNA-directed_RNA_polymerase_activity DNA-directed_RNA_polymerase_III_complex* None None 8 387236 387448 YHR143W-A S000001185 "ORF,_Verified" "RNA_polymerase_subunit,_found_in_RNA_polymerase_complexes_I,_II,_and_III" YHR144C DCD1 None pyrimidine_nucleotide_metabolism dCMP_deaminase_activity cytoplasm None None 8 388729 387791 YHR144C S000001187 "ORF,_Verified" Deoxycytidine_monophosphate_(dCMP)_deaminase_required_for_dCTP_and_dTTP_synthesis;_expression_is_NOT_cell_cycle_regulated YHR146W CRP1 None biological_process_unknown DNA_binding nucleus S/G2 None 8 390303 391700 YHR146W S000001189 "ORF,_Verified" Protein_that_binds_to_cruciform_DNA_structures YHR149C SKG6 None biological_process_unknown molecular_function_unknown bud_neck* G1 None 8 396662 394458 YHR149C S000001192 "ORF,_Verified" Integral_membrane_protein_that_localizes_primarily_to_growing_sites_such_as_the_bud_tip_or_the_cell_periphery;_potential_Cdc28p_substrate;_Skg6p_interacts_with_Zds1p_and_Zds2p YHR150W PEX28 None peroxisome_organization_and_biogenesis molecular_function_unknown peroxisomal_membrane None None 8 397254 398993 YHR150W S000001193 "ORF,_Verified" "Peroxisomal_integral_membrane_peroxin,_involved_in_the_regulation_of_peroxisomal_size,_number_and_distribution;_genetic_interactions_suggest_that_Pex28p_and_Pex29p_act_at_steps_upstream_of_those_mediated_by_Pex30p,_Pex31p,_and_Pex32p" YHR151C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G2/M None 8 400851 399271 YHR151C S000001194 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YHR151C_is_synthetically_sick_with_cdc13-1 YHR152W SPO12 None regulation_of_exit_from_mitosis* molecular_function_unknown nucleus* G2/M None 8 401437 401958 YHR152W S000001195 "ORF,_Verified" "Nucleolar_protein_of_unknown_function,_positive_regulator_of_mitotic_exit;_involved_in_regulating_release_of_Cdc14p_from_the_nucleolus_in_early_anaphase,_may_play_similar_role_in_meiosis" YHR153C SPO16 None sporulation_(sensu_Fungi) molecular_function_unknown cellular_component_unknown G1 None 8 402685 402089 YHR153C S000001196 "ORF,_Verified" "Protein_of_unknown_function,_required_for_spore_formation" YHR155W YSP1 None biological_process_unknown molecular_function_unknown mitochondrion None None 8 407106 410792 YHR155W S000001198 "ORF,_Verified" Mitochondrial_protein_with_a_potential_role_in_promoting_mitochondrial_fragmentation_during_programmed_cell_death_in_response_to_high_levels_of_alpha-factor_mating_pheromone_or_the_drug_amiodarone YHR156C LIN1 SNU40 biological_process_unknown protein_binding nucleus* None None 8 412409 411387 YHR156C S000001199 "ORF,_Verified" "Non-essential_component_of_U5_snRNP;_nuclear_protein;_physically_interacts_with_Irr1p_of_cohesin_complex;_may_link_together_proteins_involved_in_chromosome_segregation,_mRNA_splicing_and_DNA_replication" YHR157W REC104 None meiotic_recombination* molecular_function_unknown nucleus None None 8 412910 413458 YHR157W S000001200 "ORF,_Verified" Protein_involved_in_early_stages_of_meiotic_recombination;_required_for_meiotic_crossing_over;_forms_a_complex_with_Rec102p_and_Spo11p_necessary_during_the_initiation_of_recombination YHR159W None None biological_process_unknown molecular_function_unknown cytoplasm G1 None 8 417552 419066 YHR159W S000001202 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_potential_Cdc28p_substrate YHR161C YAP1801 None endocytosis clathrin_binding actin_cortical_patch None Up 8 422289 420376 YHR161C S000001204 "ORF,_Verified" "Protein_involved_in_clathrin_cage_assembly;_binds_Pan1p_and_clathrin;_homologous_to_Yap1802p,_member_of_the_AP180_protein_family" YHR163W SOL3 None tRNA_processing* 6-phosphogluconolactonase_activity cytoplasm* None None 8 423726 424475 YHR163W S000001206 "ORF,_Verified" "6-phosphogluconolactonase,_catalyzes_the_second_step_of_the_pentose_phosphate_pathway;_weak_multicopy_suppressor_of_los1-1_mutation;_homologous_to_Sol2p_and_Sol1p" YHR164C DNA2 WEB2 DNA_repair* ATP-dependent_DNA_helicase_activity* nucleus* None None 8 429180 424612 YHR164C S000001207 "ORF,_Verified" "Essential_tripartite_DNA_replication_factor_with_single-stranded_DNA-dependent_ATPase,_ATP-dependent_nuclease,_and_helicase_activities;_required_for_Okazaki_fragment_processing;_involved_in_DNA_repair_pathways;_potential_Cdc28p_substrate" YHR166C CDC23 None mitotic_sister_chromatid_segregation* protein_binding* anaphase-promoting_complex None None 8 439052 437172 YHR166C S000001209 "ORF,_Verified" "Subunit_of_the_Anaphase-Promoting_Complex/Cyclosome_(APC/C),_which_is_a_ubiquitin-protein_ligase_required_for_degradation_of_anaphase_inhibitors,_including_mitotic_cyclins,_during_the_metaphase/anaphase_transition" YHR167W THP2 None mRNA_export_from_nucleus* nucleic_acid_binding THO_complex None None 8 439344 440129 YHR167W S000001210 "ORF,_Verified" "Subunit_of_the_THO_complex,_which_connects_transcription_elongation_and_mitotic_recombination,_and_of_the_TREX_complex,_which_is_recruited_to_activated_genes_and_couples_transcription_to_mRNA_export;_involved_in_telomere_maintenance" YHR169W DBP8 None 35S_primary_transcript_processing ATP-dependent_RNA_helicase_activity nucleolus None None 8 442182 443477 YHR169W S000001212 "ORF,_Verified" "ATPase,_putative_RNA_helicase_of_the_DEAD-box_family;_component_of_90S_preribosome_complex_involved_in_production_of_18S_rRNA_and_assembly_of_40S_small_ribosomal_subunit;_ATPase_activity_stimulated_by_association_with_Esp2p" YHR170W NMD3 SRC5 ribosomal_large_subunit_assembly_and_maintenance* protein_binding* cytosol* None None 8 443829 445385 YHR170W S000001213 "ORF,_Verified" Protein_involved_in_nuclear_export_of_the_large_ribosomal_subunit;_acts_as_a_Crm1p-dependent_adapter_protein_for_export_of_nascent_ribosomal_subunits_through_the_nuclear_pore_complex YHR171W ATG7 APG7|CVT2 protein_targeting_to_vacuole* APG12_activating_enzyme_activity* cytoplasm* None None 8 445713 447605 YHR171W S000001214 "ORF,_Verified" "Autophagy-related_protein_and_dual_specificity_member_of_the_E1_family_of_ubiquitin-activating_enzymes;_mediates_the_conjugation_of_Atg12p_with_Atg5p_and_Atg8p_with_phosphatidylethanolamine,_required_steps_in_autophagosome_formation" YHR174W ENO2 None glycolysis* phosphopyruvate_hydratase_activity soluble_fraction* None None 8 451327 452640 YHR174W S000001217 "ORF,_Verified" "Enolase_II,_a_phosphopyruvate_hydratase_that_catalyzes_the_conversion_of_2-phosphoglycerate_to_phosphoenolpyruvate_during_glycolysis_and_the_reverse_reaction_during_gluconeogenesis;_expression_is_induced_in_response_to_glucose" YHR176W FMO1 None protein_folding monooxygenase_activity endoplasmic_reticulum_membrane None None 8 454229 455527 YHR176W S000001219 "ORF,_Verified" "Flavin-containing_monooxygenase,_localized_to_the_cytoplasmic_face_of_the_ER_membrane;_catalyzes_oxidation_of_biological_thiols_to_maintain_the_ER_redox_buffer_ratio_for_correct_folding_of_disulfide-bonded_proteins" YHR177W None GON3 biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 456591 457952 YHR177W S000001220 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_overexpression_causes_a_cell_cycle_delay_or_arrest YHR178W STB5 None transcription* transcription_factor_activity nucleus S/G2 None 8 459299 461530 YHR178W S000001221 "ORF,_Verified" "Activator_of_multidrug_resistance_genes,_forms_a_heterodimer_with_Pdr1p;_contains_a_Zn(II)2Cys6_zinc_finger_domain_that_interacts_with_a_PDRE_(pleotropic_drug_resistance_element)_in_vitro;_binds_Sin3p_in_a_two-hybrid_assay" YHR179W OYE2 None biological_process_unknown NADPH_dehydrogenase_activity cytoplasm* None None 8 462502 463704 YHR179W S000001222 "ORF,_Verified" "Widely_conserved_NADPH_oxidoreductase_containing_flavin_mononucleotide_(FMN),_homologous_to_Oye3p_with_slight_differences_in_ligand_binding_and_catalytic_properties;_may_be_involved_in_sterol_metabolism" YHR181W SVP26 ERV26 protein_retention_in_Golgi* protein_binding endoplasmic_reticulum* None None 8 467228 467914 YHR181W S000001224 "ORF,_Verified" "Integral_membrane_protein_of_the_early_Golgi_apparatus_and_endoplasmic_reticulum,_involved_in_COP_II_vesicle_transport;_may_also_function_to_promote_retention_of_proteins_in_the_early_Golgi_compartment" YHR182W None None biological_process_unknown molecular_function_unknown cytoplasm None None 8 468219 470576 YHR182W S000001225 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cell_periphery_and_cytoplasm YHR183W GND1 None response_to_oxidative_stress* phosphogluconate_dehydrogenase_(decarboxylating)_activity cytoplasm* None None 8 470960 472429 YHR183W S000001226 "ORF,_Verified" "6-phosphogluconate_dehydrogenase_(decarboxylating),_catalyzes_an_NADPH_regenerating_reaction_in_the_pentose_phosphate_pathway;_required_for_growth_on_D-glucono-delta-lactone_and_adaptation_to_oxidative_stress" YHR184W SSP1 SPO3 spore_wall_assembly_(sensu_Fungi)* molecular_function_unknown prospore_membrane None None 8 472744 474459 YHR184W S000001227 "ORF,_Verified" Protein_involved_in_the_control_of_meiotic_nuclear_division_and_coordination_of_meiosis_with_spore_formation;_transcription_is_induced_midway_through_meiosis YHR185C PFS1 ADY1 spore_wall_assembly_(sensu_Fungi) molecular_function_unknown cellular_component_unknown None None 8 475340 474627 YHR185C S000001228 "ORF,_Verified" "Sporulation_protein_required_for_prospore_membrane_formation_at_selected_spindle_poles,_ensures_functionality_of_all_four_spindle_pole_bodies_during_meiosis_II;_not_required_for_meiotic_recombination_or_meiotic_chromosome_segregation" YHR187W IKI1 HAP2|ELP5|TOT5 regulation_of_transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_elongation_factor_activity transcription_elongation_factor_complex* None None 8 480990 481919 YHR187W S000001230 "ORF,_Verified" "Subunit_of_Elongator_complex,_which_is_required_for_modification_of_wobble_nucleosides_in_tRNA;_iki1_mutations_confer_resistance_to_the_K._lactis_toxin_zymocin" YHR189W PTH1 PTH protein_biosynthesis aminoacyl-tRNA_hydrolase_activity mitochondrion None None 8 484028 484600 YHR189W S000001232 "ORF,_Verified" One_of_two_(see_also_PTH2)_mitochondrially-localized_peptidyl-tRNA_hydrolases;_dispensable_for_cell_growth_and_for_mitochondrial_respiration YHR192W None None biological_process_unknown molecular_function_unknown cytoplasm None None 8 486826 487662 YHR192W S000001235 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_is_induced_in_response_to_the_DNA-damaging_agent_MMS YHR193C EGD2 None cotranslational_protein_folding unfolded_protein_binding nascent_polypeptide-associated_complex None None 8 488236 487712 YHR193C S000001236 "ORF,_Verified" "Alpha_subunit_of_the_heteromeric_nascent_polypeptide-associated_complex_(NAC)_involved_in_protein_sorting_and_translocation,_associated_with_cytoplasmic_ribosomes" YHR194W MDM31 None mitochondrion_organization_and_biogenesis* molecular_function_unknown nucleus* None None 8 488657 490396 YHR194W S000001237 "ORF,_Verified" "Mitochondrial_inner_membrane_protein_with_similarity_to_Mdm32p,_required_for_normal_mitochondrial_morphology_and_inheritance;_interacts_genetically_with_MMM1,_MDM10,_MDM12,_and_MDM34" YHR196W UTP9 None processing_of_20S_pre-rRNA snoRNA_binding nucleus* None None 8 491931 493658 YHR196W S000001239 "ORF,_Verified" "Nucleolar_protein,_component_of_the_small_subunit_(SSU)_processome_containing_the_U3_snoRNA_that_is_involved_in_processing_of_pre-18S_rRNA" YHR197W RIX1 IPI2 35S_primary_transcript_processing* molecular_function_unknown nucleus* None None 8 493896 496187 YHR197W S000001240 "ORF,_Verified" "Essential_component_of_the_Rix1_complex_(Rix1p,_Ipi1p,_Ipi3p)_that_is_required_for_processing_of_ITS2_sequences_from_35S_pre-rRNA;_Rix1_complex_associates_with_Mdn1p_in_pre-60S_ribosomal_particles" YHR198C None FMP22 biological_process_unknown molecular_function_unknown mitochondrion None None 8 497280 496315 YHR198C S000001241 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation)" YHR199C None FMP34 biological_process_unknown molecular_function_unknown mitochondrion None Up 8 498422 497490 YHR199C S000001242 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation)" YHR200W RPN10 SUN1|MCB1 ubiquitin-dependent_protein_catabolism endopeptidase_activity proteasome_complex_(sensu_Eukaryota)* None None 8 499079 499885 YHR200W S000001243 "ORF,_Verified" Non-ATPase_base_subunit_of_the_19S_regulatory_particle_(RP)_of_the_26S_proteasome;_N-terminus_plays_a_role_in_maintaining_the_structural_integrity_of_the_RP;_binds_selectively_to_polyubiquitin_chains;_homolog_of_the_mammalian_S5a_protein YHR201C PPX1 None polyphosphate_metabolism exopolyphosphatase_activity cytoplasm* None None 8 501143 499950 YHR201C S000001244 "ORF,_Verified" "Exopolyphosphatase,_hydrolyzes_inorganic_polyphosphate_(poly_P)_into_Pi_residues;_located_in_the_cytosol,_plasma_membrane,_and_mitochondrial_matrix" YHR202W None None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi)* None None 8 502388 504196 YHR202W S000001245 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuole,_while_HA-tagged_protein_is_found_in_the_soluble_fraction,_suggesting_cytoplasmic_localization" YHR203C RPS4B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 8 505530 504476 YHR203C S000001246 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_identical_to_Rps4Ap_and_has_similarity_to_rat_S4_ribosomal_protein YHR204W MNL1 HTM1 ER-associated_protein_catabolism carbohydrate_binding endoplasmic_reticulum None None 8 506319 508709 YHR204W S000001247 "ORF,_Verified" Alpha_mannosidase-like_protein_of_the_endoplasmic_reticulum_required_for_degradation_of_glycoproteins_but_not_for_processing_of_N-linked_oligosaccharides YHR205W SCH9 KOM1 protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity cytoplasm* G2/M None 8 509363 511837 YHR205W S000001248 "ORF,_Verified" "Protein_kinase_involved_in_transcriptional_activation_of_osmostress-responsive_genes;_regulates_G1_progression,_cAPK_activity,_nitrogen_activation_of_the_FGM_pathway;_involved_in_life_span_regulation;_homologous_to_mammalian_Akt/PKB" YHR206W SKN7 POS9|BRY1 response_to_osmotic_stress* transcription_factor_activity* nucleus None None 8 512732 514600 YHR206W S000001249 "ORF,_Verified" "Nuclear_response_regulator_and_transcription_factor,_part_of_a_branched_two-component_signaling_system;_required_for_optimal_induction_of_heat-shock_genes_in_response_to_oxidative_stress;_involved_in_osmoregulation" YHR207C SET5 None biological_process_unknown molecular_function_unknown cytoplasm* None None 8 516485 514905 YHR207C S000001250 "ORF,_Verified" "Zinc-finger_protein_of_unknown_function,_contains_one_canonical_and_two_unusual_fingers_in_unusual_arrangements;_deletion_enhances_replication_of_positive-strand_RNA_virus" YHR208W BAT1 TWT1|ECA39 branched_chain_family_amino_acid_biosynthesis* branched-chain-amino-acid_transaminase_activity mitochondrial_matrix S/G2 None 8 517532 518713 YHR208W S000001251 "ORF,_Verified" "Mitochondrial_branched-chain_amino_acid_aminotransferase,_homolog_of_murine_ECA39;_highly_expressed_during_logarithmic_phase_and_repressed_during_stationary_phase" YHR209W CRG1 None biological_process_unknown S-adenosylmethionine-dependent_methyltransferase_activity cellular_component_unknown None None 8 519437 520312 YHR209W S000001252 "ORF,_Uncharacterized" Putative_S-adenosylmethionine-dependent_methyltransferase;_mediates_cantharidin_resistance YHR210C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 8 521737 520712 YHR210C S000001253 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene;_highly_expressed_under_anaeorbic_conditions;_sequence_similarity_to_aldose_1-epimerases_such_as_GAL10 YHR211W FLO5 None flocculation_(sensu_Saccharomyces) mannose_binding cell_wall_(sensu_Fungi) None None 8 525392 528619 YHR211W S000001254 "ORF,_Verified" "Lectin-like_cell_wall_protein_(flocculin)_involved_in_flocculation,_binds_to_mannose_chains_on_the_surface_of_other_cells,_confers_floc-forming_ability_that_is_chymotrypsin_resistant_but_heat_labile;_similar_to_Flo1p" YHR214C-B None None None None None None None 8 549346 543964 YHR214C-B S000003534 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YHR214C-C None None None None None None None 8 549346 547910 YHR214C-C S000007421 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YHR215W PHO12 PHO10 biological_process_unknown acid_phosphatase_activity vacuole_(sensu_Fungi) G2/M None 8 552099 553502 YHR215W S000001258 "ORF,_Verified" "One_of_three_repressible_acid_phosphatases,_a_glycoprotein_that_is_transported_to_the_cell_surface_by_the_secretory_pathway;_nearly_identical_to_Pho11p;_upregulated_by_phosphate_starvation" YHR216W IMD2 PUR5 GTP_biosynthesis IMP_dehydrogenase_activity cytoplasm None None 8 554396 555967 YHR216W S000001259 "ORF,_Verified" "Inosine_monophosphate_dehydrogenase,_catalyzes_the_first_step_of_GMP_biosynthesis,_expression_is_induced_by_mycophenolic_acid_resulting_in_resistance_to_the_drug,_expression_is_repressed_by_nutrient_limitation" YHR218W None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 8 558014 559924 YHR218W S000001261 "ORF,_Uncharacterized" Helicase-like_protein_encoded_within_the_telomeric_Y'_element YHR219W None None biological_process_unknown molecular_function_unknown cellular_component_unknown M/G1 None 8 560173 562047 YHR219W S000001262 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_helicases;_located_in_the_telomere_region_on_the_right_arm_of_chromosome_VIII YIL001W None None biological_process_unknown molecular_function_unknown cytoplasm None None 9 353937 355478 YIL001W S000001263 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_contains_a_BTB/POZ_domain_which_generally_function_in_protein_interactions;_deletion_slightly_improved_competitive_fitness_in_rich_media;_GFP-tagged_protein_is_localized_to_the_cytoplasm YIL004C BET1 SLY12 ER_to_Golgi_transport* v-SNARE_activity endoplasmic_reticulum_membrane* None None 9 348502 347943 YIL004C S000001266 "ORF,_Verified" Type_II_membrane_protein_required_for_vesicular_transport_between_the_endoplasmic_reticulum_and_Golgi_complex;_v-SNARE_with_similarity_to_synaptobrevins YIL005W EPS1 None protein_retention_in_ER protein_disulfide_isomerase_activity endoplasmic_reticulum_membrane None None 9 345689 347794 YIL005W S000001267 "ORF,_Verified" "ER_protein_with_chaperone_and_co-chaperone_activity,_involved_in_retention_of_resident_ER_proteins;_has_a_role_in_recognizing_proteins_targeted_for_ER-associated_degradation_(ERAD),_member_of_the_protein_disulfide_isomerase_family" YIL006W YIA6 NDT1 transport* transporter_activity* mitochondrion* None None 9 344059 345180 YIL006W S000001268 "ORF,_Verified" "Mitochondrial_NAD+_transporter,_involved_in_the_transport_of_NAD+_into_the_mitochondria_(see_also_YEA6);_member_of_the_mitochondrial_carrier_subfamily;_disputed_role_as_a_pyruvate_transporter;_has_putative_mouse_and_human_orthologs" YIL007C NAS2 None ubiquitin-dependent_protein_catabolism molecular_function_unknown cytoplasm None None 9 343653 342991 YIL007C S000001269 "ORF,_Verified" Protein_with_similarity_to_the_p27_subunit_of_mammalian_proteasome_modulator;_not_essential;_interacts_with_Rpn4p YIL008W URM1 None response_to_oxidative_stress* protein_tag cytoplasm* None None 9 342533 342832 YIL008W S000001270 "ORF,_Verified" "Ubiquitin-like_protein_with_weak_sequence_similarity_to_ubiquitin;_depends_on_the_E1-like_activating_enzyme_Uba4p;_molecular_function_of_the_Urm1p_pathway_is_unknown,_but_it_is_required_for_normal_growth,_particularly_at_high_temperature" YIL009C-A EST3 None telomerase-dependent_telomere_maintenance telomerase_activity nucleus* None None 9 336209 335663 YIL009C-A S000006432 "ORF,_Verified" "Component_of_the_telomerase_holoenzyme,_involved_in_telomere_replication" YIL009W FAA3 None lipid_metabolism* long-chain-fatty-acid-CoA_ligase_activity cellular_component_unknown M/G1 None 9 339341 341425 YIL009W S000001271 "ORF,_Verified" "Long_chain_fatty_acyl-CoA_synthetase,_has_a_preference_for_C16_and_C18_fatty_acids;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cell_periphery" YIL010W DOT5 None regulation_of_cell_redox_homeostasis thioredoxin_peroxidase_activity nucleus None None 9 334879 335526 YIL010W S000001272 "ORF,_Verified" Nuclear_thiol_peroxidase_which_functions_as_an_alkyl-hydroperoxide_reductase_during_post-diauxic_growth YIL013C PDR11 None sterol_transport "ATPase_activity,_coupled_to_transmembrane_movement_of_substances" membrane None None 9 332440 328205 YIL013C S000001275 "ORF,_Verified" "ATP-binding_cassette_(ABC)_transporter,_multidrug_transporter_involved_in_multiple_drug_resistance;_mediates_sterol_uptake_when_sterol_biosynthesis_is_compromisedregulated_by_Pdr1p;_required_for_anaerobic_growth" YIL015W BAR1 SST1 protein_catabolism aspartic-type_endopeptidase_activity periplasmic_space_(sensu_Fungi) None None 9 322340 324103 YIL015W S000001277 "ORF,_Verified" "Aspartyl_protease_secreted_into_the_periplasmic_space_of_mating_type_a_cells,_helps_cells_find_mating_partners,_cleaves_and_inactivates_alpha_factor_allowing_cells_to_recover_from_alpha-factor-induced_cell_cycle_arrest" YIL016W SNL1 None protein_folding* chaperone_regulator_activity mitochondrion* None None 9 321452 321931 YIL016W S000001278 "ORF,_Verified" Protein_of_unknown_function_proposed_to_be_involved_in_nuclear_pore_complex_biogenesis_and_maintenance_as_well_as_protein_folding;_has_similarity_to_the_mammalian_BAG-1_protein YIL017C VID28 YIL017W|GID5 negative_regulation_of_gluconeogenesis molecular_function_unknown cytoplasm* None None 9 320963 318198 YIL017C S000001279 "ORF,_Verified" "Protein_involved_in_proteasome-dependent_catabolite_degradation_of_fructose-1,6-bisphosphatase_(FBPase);_localized_to_the_nucleus_and_the_cytoplasm" YIL018W RPL2B LOT2|RPL5A protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 9 316766 317930 YIL018W S000001280 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_identical_to_Rpl2Ap_and_has_similarity_to_E._coli_L2_and_rat_L8_ribosomal_proteins;_expression_is_upregulated_at_low_temperatures" YIL019W FAF1 None processing_of_20S_pre-rRNA molecular_function_unknown cytoplasm* None None 9 315091 316131 YIL019W S000001281 "ORF,_Verified" Protein_required_for_pre-rRNA_processing_and_40S_ribosomal_subunit_assembly YIL020C HIS6 None histidine_biosynthesis 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide_isomerase_activity intracellular None None 9 314818 314033 YIL020C S000001282 "ORF,_Verified" "Phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamide_isomerase,_catalyzes_the_fourth_step_in_histidine_biosynthesis;_mutations_cause_histidine_auxotrophy_and_sensitivity_to_Cu,_Co,_and_Ni_salts" YIL022W TIM44 MPI1|MIM44|ISP45 protein_import_into_mitochondrial_matrix protein_transporter_activity mitochondrial_matrix* None None 9 311163 312458 YIL022W S000001284 "ORF,_Verified" "Peripheral_mitochondrial_membrane_protein_involved_in_mitochondrial_protein_import,_tethers_essential_chaperone_Ssc1p_to_the_translocon_channel_at_the_matrix_side_of_the_inner_membrane" YIL023C YKE4 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 310424 309384 YIL023C S000001285 "ORF,_Verified" "Zinc_transporter;_localizes_to_the_ER;_null_mutant_is_sensitive_to_calcofluor_white,_leads_to_zinc_accumulation_in_cytosol;_ortholog_of_the_mouse_KE4_and_member_of_the_ZIP_(ZRT,_IRT-like_Protein)_family" YIL024C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 309169 308600 YIL024C S000001286 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene;_expression_directly_regulated_by_the_metabolic_and_meiotic_transcriptional_regulator_Ume6p YIL026C IRR1 SCC3 mitotic_sister_chromatid_cohesion* protein_binding nucleus* G1 Up 9 307927 304475 YIL026C S000001288 "ORF,_Verified" "Subunit_of_the_cohesin_complex,_which_is_required_for_sister_chromatid_cohesion_during_mitosis_and_meiosis_and_interacts_with_centromeres_and_chromosome_arms,_essential_for_viability" YIL027C KRE27 None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 9 304102 303677 YIL027C S000001289 "ORF,_Verified" Protein_of_unknown_function;_null_mutant_shows_K1_killer_toxin_resistance YIL029C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 301255 300827 YIL029C S000001291 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_deletion_confers_sensitivity_to_4-(N-(S-glutathionylacetyl)amino)_phenylarsenoxide_(GSAO) YIL030C SSM4 KIS3|DOA10 ER-associated_protein_catabolism ubiquitin-protein_ligase_activity nuclear_envelope* None None 9 300008 296049 YIL030C S000001292 "ORF,_Verified" "Ubiquitin-protein_ligase_of_the_ER/nuclear_envelope,_required_for_degradation_of_Alpha2p_and_other_proteins_containing_a_Deg1_degradation_signal;_ssm4_mutation_suppresses_mRNA_instability_caused_by_an_rna14_mutation" YIL031W ULP2 SMT4 mitotic_spindle_checkpoint* cysteine-type_peptidase_activity* nucleus None None 9 292632 295736 YIL031W S000001293 "ORF,_Verified" "Peptidase_that_deconjugates_Smt3/SUMO-1_peptides_from_proteins,_plays_a_role_in_chromosome_cohesion_at_centromeric_regions_and_recovery_from_checkpoint_arrest_induced_by_DNA_damage_or_DNA_replication_defects;_potential_Cdc28p_substrate" YIL033C BCY1 SRA1 response_to_stress* cAMP-dependent_protein_kinase_inhibitor_activity cytoplasm* None None 9 291668 290418 YIL033C S000001295 "ORF,_Verified" "Regulatory_subunit_of_the_cyclic_AMP-dependent_protein_kinase_(PKA),_a_component_of_a_signaling_pathway_that_controls_a_variety_of_cellular_processes,_including_metabolism,_cell_cycle,_stress_response,_stationary_phase,_and_sporulation" YIL035C CKA1 None protein_amino_acid_phosphorylation* protein_kinase_CK2_activity protein_kinase_CK2_complex None None 9 288907 287789 YIL035C S000001297 "ORF,_Verified" "Alpha_catalytic_subunit_of_casein_kinase_2,_a_Ser/Thr_protein_kinase_with_roles_in_cell_growth_and_proliferation;_the_holoenzyme_also_contains_CKA2,_CKB1_and_CKB2,_the_many_substrates_include_transcription_factors_and_all_RNA_polymerases" YIL036W CST6 SHF1|ACA2 transcription_initiation_from_RNA_polymerase_II_promoter* specific_RNA_polymerase_II_transcription_factor_activity nucleus None None 9 285665 287428 YIL036W S000001298 "ORF,_Verified" "Basic_leucine_zipper_(bZIP)_transcription_factor_of_the_ATF/CREB_family,_activates_transcription_of_genes_involved_in_utilization_of_non-optimal_carbon_sources;_involved_in_telomere_maintenance" YIL037C PRM2 None conjugation_with_cellular_fusion molecular_function_unknown integral_to_membrane None None 9 284998 283028 YIL037C S000001299 "ORF,_Verified" "Pheromone-regulated_protein,_predicted_to_have_4_transmembrane_segments_and_a_coiled_coil_domain;_regulated_by_Ste12p" YIL038C NOT3 None regulation_of_transcription_from_RNA_polymerase_II_promoter* 3'-5'-exoribonuclease_activity cytoplasm* None None 9 282651 280141 YIL038C S000001300 "ORF,_Verified" "Subunit_of_the_CCR4-NOT_complex,_which_is_a_global_transcriptional_regulator_with_roles_in_transcription_initiation_and_elongation_and_in_mRNA_degradation" YIL039W TED1 None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 9 278425 279846 YIL039W S000001301 "ORF,_Uncharacterized" Conserved_phosphoesterase_domain-containing_protein_that_acts_together_with_Emp24p/Erv25p_in_cargo_exit_from_the_ER;_deletion_confers_sensitivity_to_4-(N-(S-glutathionylacetyl)amino)_phenylarsenoxide_(GSAO) YIL040W APQ12 None mRNA_export_from_nucleus molecular_function_unknown endoplasmic_reticulum* None None 9 277722 278138 YIL040W S000001302 "ORF,_Verified" Protein_involved_in_nucleocytoplasmic_transport_of_mRNA YIL041W GVP36 None biological_process_unknown molecular_function_unknown cytoplasm* None None 9 276524 277504 YIL041W S000001303 "ORF,_Verified" "BAR_domain-containing_protein_that_localizes_to_both_early_and_late_Golgi_vesicles;_required_for_adaptation_to_varying_nutrient_concentrations,_fluid-phase_endocytosis,_polarization_of_the_actin_cytoskeleton,_and_vacuole_biogenesis" YIL042C PKP1 None biological_process_unknown kinase_activity mitochondrion None None 9 276291 275107 YIL042C S000001304 "ORF,_Verified" Mitochondrial_protein_kinase_involved_in_negative_regulation_of_pyruvate_dehydrogenase_complex_activity_by_phosphorylating_the_ser-133_residue_of_the_Pda1p_subunit;_acts_in_concert_with_kinase_Pkp2p_and_phosphatases_Ptc5p_and_Ptc6p YIL043C CBR1 CBR5 electron_transport cytochrome-b5_reductase_activity mitochondrion* None None 9 274925 274071 YIL043C S000001305 "ORF,_Verified" "Microsomal_cytochrome_b_reductase,_not_essential_for_viability;_also_detected_in_mitochondria;_mutation_in_conserved_NADH_binding_domain_of_the_human_ortholog_results_in_type_I_methemoglobinemia" YIL044C AGE2 SAT2 ER_to_Golgi_transport* ARF_GTPase_activator_activity clathrin-coated_vesicle None None 9 273845 272949 YIL044C S000001306 "ORF,_Verified" "ADP-ribosylation_factor_(ARF)_GTPase_activating_protein_(GAP)_effector,_involved_in_Trans-Golgi-Network_(TGN)_transport;_contains_C2C2H2_cysteine/histidine_motif" YIL045W PIG2 None regulation_of_glycogen_biosynthesis protein_phosphatase_type_1_regulator_activity cytoplasm None None 9 271160 272776 YIL045W S000001307 "ORF,_Verified" Putative_type-1_protein_phosphatase_targeting_subunit_that_tethers_Glc7p_type-1_protein_phosphatase_to_Gsy2p_glycogen_synthase YIL046W MET30 ZRG11 protein_ubiquitination* protein_binding SCF_ubiquitin_ligase_complex* None None 9 268650 270572 YIL046W S000001308 "ORF,_Verified" "F-box_protein_containing_five_copies_of_the_WD40_motif,_controls_cell_cycle_function,_sulfur_metabolism,_and_methionine_biosynthesis_as_part_of_the_ubiquitin_ligase_complex;_interacts_with_and_regulates_Met4p,_localizes_within_the_nucleus" YIL047C SYG1 None signal_transduction molecular_function_unknown mitochondrion* None None 9 267822 265114 YIL047C S000001309 "ORF,_Verified" Plasma_membrane_protein_of_unknown_function;_truncation_and_overexpression_suppresses_lethality_of_G-alpha_protein_deficiency YIL048W NEO1 None "retrograde_transport,_Golgi_to_ER*" phospholipid-translocating_ATPase_activity* endoplasmic_reticulum_membrane* None None 9 261436 264891 YIL048W S000001310 "ORF,_Verified" Putative_aminophospholipid_translocase_(flippase)_involved_in_endocytosis_and_vacuolar_biogenesis;_localizes_to_endosomes_and_the_Golgi_aparatus YIL049W DFG10 None pseudohyphal_growth molecular_function_unknown cellular_component_unknown None None 9 260157 260918 YIL049W S000001311 "ORF,_Verified" "Protein_of_unknown_function,_involved_in_filamentous_growth" YIL050W PCL7 None regulation_of_glycogen_biosynthesis* cyclin-dependent_protein_kinase_regulator_activity cyclin-dependent_protein_kinase_holoenzyme_complex S/G2 None 9 258912 259769 YIL050W S000001312 "ORF,_Verified" "Pho85p_cyclin_of_the_Pho80p_subfamily,_forms_a_functional_kinase_complex_with_Pho85p_which_phosphorylates_Mmr1p_and_is_regulated_by_Pho81p;_involved_in_glycogen_metabolism,_expression_is_cell-cycle_regulated" YIL051C MMF1 IBM1 mitochondrial_genome_maintenance* molecular_function_unknown mitochondrion* None None 9 258279 257842 YIL051C S000001313 "ORF,_Verified" Mitochondrial_protein_involved_in_maintenance_of_the_mitochondrial_genome YIL052C RPL34B None protein_biosynthesis* structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 9 257061 256224 YIL052C S000001314 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl34Ap_and_has_similarity_to_rat_L34_ribosomal_protein" YIL053W RHR2 GPP1 response_to_osmotic_stress* glycerol-1-phosphatase_activity cytoplasm* None None 9 255113 255865 YIL053W S000001315 "ORF,_Verified" "Constitutively_expressed_isoform_of_DL-glycerol-3-phosphatase;_involved_in_glycerol_biosynthesis,_induced_in_response_to_both_anaerobic_and,_along_with_the_Hor2p/Gpp2p_isoform,_osmotic_stress" YIL055C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 253923 252040 YIL055C S000001317 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YIL056W VHR1 None biological_process_unknown molecular_function_unknown cytoplasm* G2/M None 9 249989 251911 YIL056W S000001318 "ORF,_Verified" "Transcriptional_activator,_required_for_the_vitamin_H-responsive_element_(VHRE)_mediated_induction_of_VHT1_(Vitamin_H_transporter)_and_BIO5_(biotin_biosynthesis_intermediate_transporter)_in_response_to_low_biotin_concentrations" YIL057C None None biological_process_unknown molecular_function_unknown cytoplasm None None 9 248393 247899 YIL057C S000001319 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_expression_induced_under_carbon_limitation_and_repressed_under_high_glucose YIL060W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 246389 246823 YIL060W S000001322 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_mutant_accumulates_less_glycogen_than_does_wild_type;_null_mutation_results_in_a_decrease_in_plasma_membrane_electron_transport;_YIL060W_is_not_an_essential_gene YIL061C SNP1 None "nuclear_mRNA_splicing,_via_spliceosome" mRNA_binding* snRNP_U1* None None 9 245556 244654 YIL061C S000001323 "ORF,_Verified" Component_of_U1_snRNP_required_for_mRNA_splicing_via_spliceosome;_may_interact_with_poly(A)_polymerase_to_regulate_polyadenylation;_homolog_of_human_U1_70K_protein YIL063C YRB2 None protein_export_from_nucleus molecular_function_unknown nucleus* None None 9 243741 242758 YIL063C S000001325 "ORF,_Verified" "Protein_of_unknown_function_involved_in_nuclear_processes_of_the_Ran-GTPase_cycle;_involved_in_nuclear_protein_export;_contains_Ran_Binding_Domain_and_FxFG_repeats;_interacts_with_Srm1p,_GTP-Gsp1p,_Rna1p_and_Crm1p;_is_not_essential" YIL064W None None biological_process_unknown S-adenosylmethionine-dependent_methyltransferase_activity cytoplasm None None 9 241940 242713 YIL064W S000001326 "ORF,_Uncharacterized" Putative_S-adenosylmethionine-dependent_methyltransferase_of_the_seven_beta-strand_family YIL065C FIS1 MDV2 mitochondrial_fission molecular_function_unknown mitochondrial_outer_membrane None None 9 241772 241305 YIL065C S000001327 "ORF,_Verified" "Mitochondrial_outer_membrane_protein_involved_in_membrane_fission,_required_for_localization_of_Dnm1p_and_Mdv1p_during_mitochondrial_division;_mediates_ethanol-induced_apoptosis_and_ethanol-induced_mitochondrial_fragmentation" YIL066C RNR3 RIR3|DIN1 DNA_replication ribonucleoside-diphosphate_reductase_activity cytoplasm* G1 Up 9 240705 238096 YIL066C S000001328 "ORF,_Verified" "One_of_two_large_regulatory_subunits_of_ribonucleotide-diphosphate_reductase;_the_RNR_complex_catalyzes_rate-limiting_step_in_dNTP_synthesis,_regulated_by_DNA_replication_and_DNA_damage_checkpoint_pathways_via_localization_of_small_subunits" YIL067C None None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) None None 9 237757 235721 YIL067C S000001329 "ORF,_Uncharacterized" Uncharacterized_protein_of_unknown_function YIL068C SEC6 None cytokinesis* protein_binding bud_tip* None Up 9 235471 233054 YIL068C S000001330 "ORF,_Verified" "Essential_88kDa_subunit_of_the_exocyst_complex,_which_mediates_polarized_targeting_of_secretory_vesicles_to_active_sites_of_exocytosis;_dimeric_form_of_Sec6p_interacts_with_Sec9p_in_vitro_and_inhibits_t-SNARE_assembly" YIL069C RPS24B RPS24EB protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 9 232366 231550 YIL069C S000001331 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_identical_to_Rps24Ap_and_has_similarity_to_rat_S24_ribosomal_protein YIL070C MAM33 None aerobic_respiration molecular_function_unknown mitochondrial_matrix None None 9 231069 230269 YIL070C S000001332 "ORF,_Verified" Acidic_protein_of_the_mitochondrial_matrix_involved_in_oxidative_phosphorylation;_related_to_the_human_complement_receptor_gC1q-R YIL071C PCI8 YIL071W|CSN11|YIH1 protein_deneddylation molecular_function_unknown signalosome_complex None None 9 229991 228657 YIL071C S000001333 "ORF,_Verified" "Possible_shared_subunit_of_Cop9_signalosome_(CSN)_and_eIF3,_binds_eIF3b_subunit_Prt1p,_has_possible_dual_functions_in_transcriptional_and_translational_control,_contains_a_PCI_(Proteasome-COP9_signalosome_(CSN)-eIF3)_domain" YIL073C SPO22 ZIP4 meiosis molecular_function_unknown cellular_component_unknown None None 9 225951 222934 YIL073C S000001335 "ORF,_Verified" "Meiosis-specific_protein_essential_for_chromosome_synapsis,_involved_in_completion_of_nuclear_divisions_during_meiosis;_induced_early_in_meiosis" YIL074C SER33 None serine_family_amino_acid_biosynthesis phosphoglycerate_dehydrogenase_activity cytoplasm S None 9 222487 221078 YIL074C S000001336 "ORF,_Verified" "3-phosphoglycerate_dehydrogenase,_catalyzes_the_first_step_in_serine_and_glycine_biosynthesis;_isozyme_of_Ser3p" YIL075C RPN2 SEN3 ubiquitin-dependent_protein_catabolism endopeptidase_activity* nucleus* None None 9 220697 217860 YIL075C S000001337 "ORF,_Verified" "Subunit_of_the_26S_proteasome,_substrate_of_the_N-acetyltransferase_Nat1p" YIL077C None None biological_process_unknown molecular_function_unknown mitochondrion None None 9 215950 214988 YIL077C S000001339 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_deletion_confers_sensitivity_to_4-(N-(S-glutathionylacetyl)amino)_phenylarsenoxide_(GSAO)" YIL078W THS1 None protein_biosynthesis threonine-tRNA_ligase_activity cytoplasm* None None 9 212496 214700 YIL078W S000001340 "ORF,_Verified" "Threonyl-tRNA_synthetase,_essential_cytoplasmic_protein" YIL079C AIR1 None mRNA_export_from_nucleus* molecular_function_unknown nucleus* None None 9 212002 210920 YIL079C S000001341 "ORF,_Verified" "RING_finger_protein_that_interacts_with_the_arginine_methyltransferase_Hmt1p_to_regulate_methylation_of_Npl3p,_which_modulates_Npl3p_function_in_mRNA_processing_and_export;_has_similarity_to_Air2p" YIL080W None None Ty_element_transposition protein_binding* retrotransposon_nucleocapsid None None 9 205632 210354 YIL080W S000001342 "pseudogene,_None" "TyB_Gag-Pol_protein;_proteolytically_processed_to_make_the_Gag,_RT,_PR,_and_IN_proteins_that_are_required_for_retrotransposition" YIL083C None None coenzyme_A_biosynthesis phosphopantothenate-cysteine_ligase_activity cytoplasm* None None 9 204650 203553 YIL083C S000001345 "ORF,_Uncharacterized" "Putative_phosphopantothenoylcysteine_synthetase_(PPCS)_that_catalyzes_the_second_step_in_the_biosynthesis_of_coenzyme_A_from_pantothenate;_conserved_in_bacteria,_humans,_and_plants;_essential_for_viability" YIL084C SDS3 None chromatin_silencing* protein_binding histone_deacetylase_complex None None 9 203256 202273 YIL084C S000001346 "ORF,_Verified" "Component_of_the_Rpd3p/Sin3p_deacetylase_complex_required_for_its_structural_integrity_and_catalytic_activity,_involved_in_transcriptional_silencing_and_required_for_sporulation;_cells_defective_in_SDS3_display_pleiotropic_phenotypes" YIL085C KTR7 None cell_wall_organization_and_biogenesis* mannosyltransferase_activity Golgi_apparatus None None 9 202040 200487 YIL085C S000001347 "ORF,_Verified" Putative_mannosyltransferase_involved_in_protein_glycosylation;_member_of_the_KRE2/MNT1_mannosyltransferase_family YIL087C None None biological_process_unknown molecular_function_unknown mitochondrion None None 9 200116 199643 YIL087C S000001349 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_protein_is_detected_in_purified_mitochondria_in_high-throughput_studies;_null_mutant_displays_decreased_mitochondrial_genome_loss_(petite_formation)_and_severe_growth_defect_in_minimal_glycerol_media YIL089W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 195596 196213 YIL089W S000001351 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YIL090W ICE2 None ER_organization_and_biogenesis molecular_function_unknown endoplasmic_reticulum None None 9 193592 195067 YIL090W S000001352 "ORF,_Verified" Integral_ER_membrane_protein_with_type-III_transmembrane_domains;_mutations_cause_defects_in_cortical_ER_morphology_in_both_the_mother_and_daughter_cells YIL091C None None biological_process_unknown RNA_helicase_activity nucleus* None None 9 193192 191027 YIL091C S000001353 "ORF,_Uncharacterized" Nucleolar_protein_of_unknown_function;_proposed_to_function_as_an_RNA_helicase_based_on_structure_prediction_and_remote_homology_searches;_essential_for_viability YIL092W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 9 189063 190964 YIL092W S000001354 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_to_the_nucleus YIL093C RSM25 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 9 188781 187987 YIL093C S000001355 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YIL094C LYS12 LYS11|LYS10 lysine_biosynthesis homoisocitrate_dehydrogenase_activity cytoplasm* G2/M None 9 187629 186514 YIL094C S000001356 "ORF,_Verified" "Homo-isocitrate_dehydrogenase,_an_NAD-linked_mitochondrial_enzyme_required_for_the_fourth_step_in_the_biosynthesis_of_lysine,_in_which_homo-isocitrate_is_oxidatively_decarboxylated_to_alpha-ketoadipate" YIL096C None None biological_process_unknown molecular_function_unknown nucleus* None None 9 183124 182114 YIL096C S000001358 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_associates_with_precursors_of_the_60S_ribosomal_subunit YIL097W FYV10 GID9 negative_regulation_of_gluconeogenesis molecular_function_unknown cytoplasm* None None 9 180424 181974 YIL097W S000001359 "ORF,_Verified" "Protein_of_unknown_function,_required_for_survival_upon_exposure_to_K1_killer_toxin;_involved_in_proteasome-dependent_catabolite_inactivation_of_FBPase;_contains_CTLH_domain;_plays_role_in_anti-apoptosis" YIL099W SGA1 None sporulation_(sensu_Fungi)* "glucan_1,4-alpha-glucosidase_activity" vacuole_(sensu_Fungi) None None 9 178001 179650 YIL099W S000001361 "ORF,_Verified" "Intracellular_sporulation-specific_glucoamylase_involved_in_glycogen_degradation;_induced_during_starvation_of_a/a_diploids_late_in_sporulation,_but_dispensable_for_sporulation" YIL101C XBP1 None response_to_stress transcription_factor_activity nucleus None None 9 177247 175304 YIL101C S000001363 "ORF,_Verified" "Transcriptional_repressor_that_binds_to_promoter_sequences_of_the_cyclin_genes,_CYS3,_and_SMF2;_expression_is_induced_by_stress_or_starvation_during_mitosis,_and_late_in_meiosis;_member_of_the_Swi4p/Mbp1p_family;_potential_Cdc28p_substrate" YIL104C SHQ1 None snoRNA_metabolism molecular_function_unknown nucleoplasm G1 None 9 171502 169979 YIL104C S000001366 "ORF,_Verified" "Protein_required_for_the_assembly_of_box_H/ACA_snoRNPs_and_thus_for_pre-rRNA_processing,_forms_a_complex_with_Naf1p_and_interacts_with_H/ACA_snoRNP_components_Nhp2p_and_Cbf5p" YIL105C SLM1 LIT2 actin_cytoskeleton_organization_and_biogenesis* phosphoinositide_binding cytoplasm* None None 9 169638 167578 YIL105C S000001367 "ORF,_Verified" "Phosphoinositide_PI4,5P(2)_binding_protein,_forms_a_complex_with_Slm2p;_acts_downstream_of_Mss4p_in_a_pathway_regulating_actin_cytoskeleton_organization_in_response_to_stress;_phosphorylated_by_the_TORC2_complex" YIL106W MOB1 None protein_amino_acid_phosphorylation* kinase_regulator_activity bud_neck* G2/M None 9 166412 167441 YIL106W S000001368 "ORF,_Verified" Component_of_the_mitotic_exit_network;_associates_with_and_is_required_for_the_activation_and_Cdc15p-dependent_phosphorylation_of_the_Dbf2p_kinase;_required_for_cytokinesis_and_cell_separation;_component_of_the_CCR4_transcriptional_complex YIL107C PFK26 None "fructose_2,6-bisphosphate_metabolism*" 6-phosphofructo-2-kinase_activity cytoplasm None None 9 165758 163275 YIL107C S000001369 "ORF,_Verified" "6-phosphofructo-2-kinase,_inhibited_by_phosphoenolpyruvate_and_sn-glycerol_3-phosphate,_has_negligible_fructose-2,6-bisphosphatase_activity,_transcriptional_regulation_involves_protein_kinase_A" YIL108W None None proteolysis metalloendopeptidase_activity cytoplasm None None 9 160884 162974 YIL108W S000001370 "ORF,_Uncharacterized" Putative_metalloprotease YIL112W HOS4 None histone_deacetylation* NAD-dependent_histone_deacetylase_activity* histone_deacetylase_complex None None 9 151592 154843 YIL112W S000001374 "ORF,_Verified" "Subunit_of_the_Set3_complex,_which_is_a_meiotic-specific_repressor_of_sporulation_specific_genes_that_contains_deacetylase_activity;_potential_Cdc28p_substrate" YIL113W SDP1 None MAPKKK_cascade_during_cell_wall_biogenesis MAP_kinase_phosphatase_activity cytoplasm* None None 9 150556 151185 YIL113W S000001375 "ORF,_Verified" "Stress-inducible_dual-specificity_MAP_kinase_phosphatase,_negatively_regulates_Slt2p_MAP_kinase_by_direct_dephosphorylation,_diffuse_localization_under_normal_conditions_shifts_to_punctate_localization_after_heat_shock" YIL114C POR2 YVDAC2 ion_transport voltage-gated_ion-selective_channel_activity mitochondrion* M/G1 None 9 149985 149140 YIL114C S000001376 "ORF,_Verified" "Putative_mitochondrial_porin_(voltage-dependent_anion_channel),_related_to_Por1p_but_not_required_for_mitochondrial_membrane_permeability_or_mitochondrial_osmotic_stability" YIL116W HIS5 None histidine_biosynthesis histidinol-phosphate_transaminase_activity intracellular None Up 9 142925 144082 YIL116W S000001378 "ORF,_Verified" "Histidinol-phosphate_aminotransferase,_catalyzes_the_seventh_step_in_histidine_biosynthesis;_responsive_to_general_control_of_amino_acid_biosynthesis;_mutations_cause_histidine_auxotrophy_and_sensitivity_to_Cu,_Co,_and_Ni_salts" YIL117C PRM5 None conjugation_with_cellular_fusion molecular_function_unknown integral_to_membrane S None 9 141566 140610 YIL117C S000001379 "ORF,_Verified" "Pheromone-regulated_protein,_predicted_to_have_1_transmembrane_segment;_induced_during_cell_integrity_signaling" YIL118W RHO3 None actin_filament_organization* GTPase_activity* intracellular None None 9 139749 140444 YIL118W S000001380 "ORF,_Verified" Non-essential_small_GTPase_of_the_Rho/Rac_subfamily_of_Ras-like_proteins_involved_in_the_establishment_of_cell_polarity;_GTPase_activity_positively_regulated_by_the_GTPase_activating_protein_(GAP)_Rgd1p YIL119C RPI1 None thiamin_biosynthesis* small_GTPase_regulator_activity nucleus G2/M None 9 137874 136651 YIL119C S000001381 "ORF,_Verified" Putative_transcriptional_regulator;_overexpression_suppresses_the_heat_shock_sensitivity_of_wild-type_RAS2_overexpression_and_also_suppresses_the_cell_lysis_defect_of_an_mpk1_mutation YIL120W QDR1 None multidrug_transport multidrug_transporter_activity* plasma_membrane* None None 9 134414 136105 YIL120W S000001382 "ORF,_Verified" "Multidrug_transporter_of_the_major_facilitator_superfamily,_required_for_resistance_to_quinidine,_ketoconazole,_fluconazole,_and_barban" YIL121W QDR2 None multidrug_transport multidrug_efflux_pump_activity integral_to_plasma_membrane G2/M None 9 132241 133869 YIL121W S000001383 "ORF,_Verified" "Multidrug_transporter_of_the_major_facilitator_superfamily,_required_for_resistance_to_quinidine,_barban,_cisplatin,_and_bleomycin;_may_have_a_role_in_potassium_uptake" YIL122W POG1 None G1/S-specific_transcription_in_mitotic_cell_cycle* specific_RNA_polymerase_II_transcription_factor_activity nucleus G2/M None 9 130607 131662 YIL122W S000001384 "ORF,_Verified" Putative_transcriptional_activator_that_promotes_recovery_from_pheromone_induced_arrest;_inhibits_both_alpha-factor_induced_G1_arrest_and_repression_of_CLN1_and_CLN2_via_SCB/MCB_promoter_elements;_potential_Cdc28p_substrate;_SBF_regulated YIL123W SIM1 None microtubule_cytoskeleton_organization_and_biogenesis molecular_function_unknown cell_wall_(sensu_Fungi) S/G2 None 9 128151 129578 YIL123W S000001385 "ORF,_Verified" "Protein_of_the_SUN_family_(Sim1p,_Uth1p,_Nca3p,_Sun4p)_that_may_participate_in_DNA_replication,_promoter_contains_SCB_regulation_box_at_-300_bp_indicating_that_expression_may_be_cell_cycle-regulated" YIL124W AYR1 None phosphatidic_acid_biosynthesis acylglycerone-phosphate_reductase_activity cytoplasm* None None 9 126204 127097 YIL124W S000001386 "ORF,_Verified" "NADPH-dependent_1-acyl_dihydroxyacetone_phosphate_reductase_found_in_lipid_particles,_ER,_and_mitochondrial_outer_membrane;_involved_in_phosphatidic_acid_biosynthesis;_required_for_spore_germination;_capable_of_metabolizing_steroid_hormones" YIL125W KGD1 OGD1 tricarboxylic_acid_cycle* oxoglutarate_dehydrogenase_(succinyl-transferring)_activity mitochondrial_matrix* None None 9 122689 125733 YIL125W S000001387 "ORF,_Verified" "Component_of_the_mitochondrial_alpha-ketoglutarate_dehydrogenase_complex,_which_catalyzes_a_key_step_in_the_tricarboxylic_acid_(TCA)_cycle,_the_oxidative_decarboxylation_of_alpha-ketoglutarate_to_form_succinyl-CoA" YIL126W STH1 NPS1 chromatin_remodeling* ATPase_activity* RSC_complex None None 9 117992 122071 YIL126W S000001388 "ORF,_Verified" ATPase_component_of_the_RSC_chromatin_remodeling_complex;_required_for_expression_of_early_meiotic_genes;_essential_helicase-related_protein_homologous_to_Snf2p YIL127C None None biological_process_unknown molecular_function_unknown nucleolus None None 9 117644 117024 YIL127C S000001389 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleolus YIL129C TAO3 PAG1 cellular_morphogenesis* molecular_function_unknown mitochondrion* S/G2 None 9 113237 106107 YIL129C S000001391 "ORF,_Verified" "Protein_involved_in_cell_morphogenesis_and_proliferation,_associated_with_protein_kinase_Cbk1p;_mutants_activate_OCH1_transcription" YIL130W ASG1 None biological_process_unknown molecular_function_unknown nucleus None None 9 102782 105676 YIL130W S000001392 "ORF,_Verified" "Proposed_transcriptional_activator,_member_of_the_Gal4p_family_of_zinc_cluster_proteins" YIL131C FKH1 None pseudohyphal_growth* transcription_factor_activity nucleus S/G2 None 9 102235 100781 YIL131C S000001393 "ORF,_Verified" Forkhead_family_transcription_factor_with_a_minor_role_in_the_expression_of_G2/M_phase_genes;_negatively_regulates_transcriptional_elongation;_positive_role_in_chromatin_silencing_at_HML_and_HMR;_regulates_donor_preference_during_switching YIL132C CSM2 None meiotic_chromosome_segregation* molecular_function_unknown cytoplasm* G1 None 9 100501 99860 YIL132C S000001394 "ORF,_Verified" Protein_required_for_accurate_chromosome_segregation_during_meiosis YIL133C RPL16A RPL13 protein_biosynthesis structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 9 99416 98527 YIL133C S000001395 "ORF,_Verified" "N-terminally_acetylated_protein_component_of_the_large_(60S)_ribosomal_subunit,_binds_to_5.8_S_rRNA;_has_similarity_to_Rpl16Bp,_E._coli_L13_and_rat_L13a_ribosomal_proteins;_transcriptionally_regulated_by_Rap1p" YIL134W FLX1 None FAD_transport FAD_transporter_activity mitochondrion None None 9 97395 98330 YIL134W S000001396 "ORF,_Verified" "Protein_required_for_transport_of_flavin_adenine_dinucleotide_(FAD),_a_synthesis_product_of_riboflavin,_across_the_mitochondrial_membrane" YIL135C VHS2 None G1/S_transition_of_mitotic_cell_cycle molecular_function_unknown cytoplasm S/G2 None 9 96375 95065 YIL135C S000001397 "ORF,_Verified" "Cytoplasmic_protein_of_unknown_function;_identified_as_a_high-copy_suppressor_of_the_synthetic_lethality_of_a_sis2_sit4_double_mutant,_suggesting_a_role_in_G1/S_phase_progression;_similar_to_Mlf3p" YIL136W OM45 None biological_process_unknown molecular_function_unknown mitochondrial_outer_membrane None Up 9 93619 94800 YIL136W S000001398 "ORF,_Verified" "Protein_of_unknown_function,_major_constituent_of_the_mitochondrial_outer_membrane;_located_on_the_outer_(cytosolic)_face_of_the_outer_membrane" YIL137C TMA108 RBF108 proteolysis metalloendopeptidase_activity cytoplasm None None 9 92788 89948 YIL137C S000001399 "ORF,_Verified" Protein_that_associates_with_ribosomes;_putative_metalloprotease YIL138C TPM2 None actin_filament_organization* actin_lateral_binding contractile_ring_(sensu_Saccharomyces)* S/G2 None 9 89715 89230 YIL138C S000001400 "ORF,_Verified" "Minor_isoform_of_tropomyosin,_binds_to_and_stabilizes_actin_cables_and_filaments,_which_direct_polarized_cell_growth_and_the_distribution_of_several_organelles;_appears_to_have_distinct_and_also_overlapping_functions_with_Tpm1p" YIL139C REV7 None DNA_repair* zeta_DNA_polymerase_activity zeta_DNA_polymerase_complex None None 9 88716 87979 YIL139C S000001401 "ORF,_Verified" "Processivity_subunit_of_DNA_polymerase_zeta,_which_is_involved_in_DNA_repair_and_translesion_synthesis;_required_for_mutagenesis_induced_by_DNA_damage" YIL140W AXL2 SRO4|BUD10 bud_site_selection* molecular_function_unknown bud_neck* G1 None 9 85366 87837 YIL140W S000001402 "ORF,_Verified" "Integral_plasma_membrane_protein_required_for_axial_budding_in_haploid_cells,_localizes_to_the_incipient_bud_site_and_bud_neck;_glycosylated_by_Pmt4p;_potential_Cdc28p_substrate" YIL142W CCT2 TCP2|BIN3 protein_folding* unfolded_protein_binding cytoplasm* None None 9 83302 84885 YIL142W S000001404 "ORF,_Verified" "Subunit_beta_of_the_cytosolic_chaperonin_Cct_ring_complex,_related_to_Tcp1p,_required_for_the_assembly_of_actin_and_tubulins_in_vivo" YIL143C SSL2 RAD25|LOM3 transcription_initiation_from_RNA_polymerase_II_promoter* general_RNA_polymerase_II_transcription_factor_activity* transcription_factor_TFIIH_complex* None None 9 83041 80510 YIL143C S000001405 "ORF,_Verified" "Component_of_the_holoenzyme_form_of_RNA_polymerase_transcription_factor_TFIIH,_has_DNA-dependent_ATPase/helicase_activity_and_is_required,_with_Rad3p,_for_unwinding_promoter_DNA;_involved_in_DNA_repair;_homolog_of_human_ERCC3" YIL144W TID3 HEC1|NDC80 chromosome_segregation* structural_constituent_of_cytoskeleton condensed_nuclear_chromosome_kinetochore* S None 9 78074 80149 YIL144W S000001406 "ORF,_Verified" "Component_of_the_evolutionarily_conserved_kinetochore-associated_Ndc80_complex_(Ndc80p-Nuf2p-Spc24p-Spc25p);_conserved_coiled-coil_protein_involved_in_chromosome_segregation,_spindle_checkpoint_activity,_kinetochore_assembly_and_clustering" YIL145C PAN6 None pantothenate_biosynthesis pantoate-beta-alanine_ligase_activity cytoplasm* None None 9 77283 76354 YIL145C S000001407 "ORF,_Verified" "Pantothenate_synthase,_also_known_as_pantoate-beta-alanine_ligase,_required_for_pantothenic_acid_biosynthesis,_deletion_causes_pantothenic_acid_auxotrophy,_homologous_to_E._coli_panC" YIL146C ECM37 None cell_wall_organization_and_biogenesis molecular_function_unknown cellular_component_unknown None None 9 75773 74184 YIL146C S000001408 "ORF,_Verified" Non-essential_protein_of_unknown_function YIL147C SLN1 YPD2 protein_amino_acid_phosphorylation* osmosensor_activity* plasma_membrane None None 9 73453 69791 YIL147C S000001409 "ORF,_Verified" "Histidine_kinase_osmosensor_that_regulates_a_MAP_kinase_cascade;_transmembrane_protein_with_an_intracellular_kinase_domain_that_signals_to_Ypd1p_and_Ssk1p,_thereby_forming_a_phosphorelay_system_similar_to_bacterial_two-component_regulators" YIL148W RPL40A UB11|UBI1|CEP52A protein_biosynthesis* structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 9 68708 69528 YIL148W S000001410 "ORF,_Verified" "Fusion_protein,_identical_to_Rpl40Bp,_that_is_cleaved_to_yield_ubiquitin_and_a_ribosomal_protein_of_the_large_(60S)_ribosomal_subunit_with_similarity_to_rat_L40;_ubiquitin_may_facilitate_assembly_of_the_ribosomal_protein_into_ribosomes" YIL149C MLP2 None mRNA_export_from_nucleus* ribonucleoprotein_binding mitochondrion* None None 9 68067 63028 YIL149C S000001411 "ORF,_Verified" "Myosin-like_protein_associated_with_the_nuclear_envelope,_connects_the_nuclear_pore_complex_with_the_nuclear_interior;_involved_in_the_Tel1p_pathway_that_controls_telomere_length" YIL150C MCM10 DNA43 chromatin_silencing_at_telomere* chromatin_binding nucleus None None 9 62728 61013 YIL150C S000001412 "ORF,_Verified" Essential_chromatin-associated_protein_involved_in_the_initiation_of_DNA_replication;_required_for_the_association_of_the_MCM2-7_complex_with_replication_origins YIL153W RRD1 YPA1 DNA_repair* protein_phosphatase_type_2A_regulator_activity cytoplasm* None None 9 55198 56379 YIL153W S000001415 "ORF,_Verified" "Peptidyl-prolyl_cis/trans-isomerase,_activator_of_the_phosphotyrosyl_phosphatase_activity_of_PP2A;_involved_in_G1_phase_progression,_microtubule_dynamics,_bud_morphogenesis_and_DNA_repair;_subunit_of_the_Tap42p-Sit4p-Rrd1p_complex" YIL154C IMP2' IMP2 DNA_repair* transcription_coactivator_activity cytoplasm None None 9 55021 53981 YIL154C S000001416 "ORF,_Verified" "Transcriptional_activator_involved_in_maintenance_of_ion_homeostasis_and_protection_against_DNA_damage_caused_by_bleomycin_and_other_oxidants,_contains_a_C-terminal_leucine-rich_repeat" YIL155C GUT2 None carbohydrate_metabolism* glycerol-3-phosphate_dehydrogenase_activity mitochondrion None Up 9 53708 51759 YIL155C S000001417 "ORF,_Verified" "Mitochondrial_glycerol-3-phosphate_dehydrogenase;_expression_is_repressed_by_both_glucose_and_cAMP_and_derepressed_by_non-fermentable_carbon_sources_in_a_Snf1p,_Rsf1p,_Hap2/3/4/5_complex_dependent_manner" YIL156W UBP7 None protein_deubiquitination ubiquitin-specific_protease_activity cytoplasm None None 9 48091 51306 YIL156W S000001418 "ORF,_Verified" Ubiquitin-specific_protease_that_cleaves_ubiquitin-protein_fusions YIL157C COA1 FMP35 biological_process_unknown molecular_function_unknown mitochondrion None None 9 47542 46949 YIL157C S000001419 "ORF,_Verified" Mitochondrial_inner_membrane_protein_required_for_assembly_of_the_cytochrome_c_oxidase_complex_(complex_IV);_interacts_with_complex_IV_assembly_factor_Shy1p_during_the_early_stages_of_assembly YIL158W None None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) G2/M Down 9 46201 46815 YIL158W S000001420 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_overexpression_causes_a_cell_cycle_delay_or_arrest;_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuole YIL159W BNR1 None actin_filament_organization* cytoskeletal_protein_binding contractile_ring_(sensu_Saccharomyces) None None 9 41825 45952 YIL159W S000001421 "ORF,_Verified" "Formin,_nucleates_the_formation_of_linear_actin_filaments,_involved_in_cell_processes_such_as_budding_and_mitotic_spindle_orientation_which_require_the_formation_of_polarized_actin_cables,_functionally_redundant_with_BNI1" YIL161W None None biological_process_unknown molecular_function_unknown cytoplasm None None 9 39433 40140 YIL161W S000001423 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_mRNA_is_enriched_in_Scp160p-associated_mRNPs;_YIL161W_is_a_non-essential_gene YIL162W SUC2 None sucrose_catabolism beta-fructofuranosidase_activity cytoplasm* G2/M None 9 37385 38983 YIL162W S000001424 "ORF,_Verified" "Invertase,_sucrose_hydrolyzing_enzyme;_a_secreted,_glycosylated_form_is_regulated_by_glucose_repression,_and_an_intracellular,_nonglycosylated_enzyme_is_produced_constitutively" YIL164C NIT1 None biological_process_unknown nitrilase_activity cellular_component_unknown None Up 9 34686 34087 YIL164C S000001426 "ORF,_Verified" "Nitrilase,_member_of_the_nitrilase_branch_of_the_nitrilase_superfamily;_in_closely_related_species_and_other_S._cerevisiae_strain_backgrounds_YIL164C_and_adjacent_ORF,_YIL165C,_likely_constitute_a_single_ORF_encoding_a_nitrilase_gene" YIL165C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None Up 9 34077 33718 YIL165C S000001427 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_in_closely_related_species_and_other_S._cerevisiae_strain_backgrounds_YIL165C_and_adjacent_ORF,_YIL164C,_likely_constitute_a_single_ORF_encoding_a_nitrilase_gene" YIL166C None None transport transporter_activity membrane None None 9 32566 30938 YIL166C S000001428 "ORF,_Uncharacterized" Putative_protein_with_similarity_to_the_allantoate_permease_(Dal5p)_subfamily_of_the_major_facilitator_superfamily;_mRNA_expression_is_elevated_by_sulfur_limitation;_YIL166C_is_a_non-essential_gene YIL167W SDL1 None serine_family_amino_acid_metabolism L-serine_ammonia-lyase_activity cellular_component_unknown G2/M None 9 29416 30048 YIL167W S000001429 "pseudogene,_None" "Open_reading_frame,_unlikely_to_produce_a_functional_protein_in_S288C;_in_closely_related_species_and_other_S._cerevisiae_strain_backgrounds_YIL167W_and_adjacent_ORF,_YIL168W,_constitute_a_single_ORF_encoding_L-serine_dehydratase" YIL168W None SDL1 serine_family_amino_acid_metabolism L-serine_ammonia-lyase_activity cellular_component_unknown G2/M None 9 29032 29415 YIL168W S000001430 "pseudogene,_None" "Open_reading_frame,_unlikely_to_produce_a_functional_protein_in_S288C;_in_closely_related_species_and_other_S._cerevisiae_strain_backgrounds_YIL168W_and_adjacent_ORF,_YIL167W,_constitute_a_single_ORF_encoding_L-serine_dehydratase" YIL169C None HPF1' biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 26106 23119 YIL169C S000001431 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_serine/threonine_rich_and_highly_similar_to_YOL155C,_a_putative_glucan_alpha-1,4-glucosidase;_transcript_is_induced_in_both_high_and_low_pH_environments;_YIL169C_is_a_non-essential_gene" YIL170W HXT12 None biological_process_unknown* molecular_function_unknown* cellular_component_unknown None None 9 19847 21220 YIL170W S000001432 "pseudogene,_None" "Possible_pseudogene_in_strain_S288C;_YIL170W/HXT12_and_the_adjacent_ORF,_YIL171W,_together_encode_a_non-functional_member_of_the_hexose_transporter_family" YIL172C None None biological_process_unknown glucosidase_activity cytoplasm None None 9 18553 16784 YIL172C S000001434 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_glucosidases;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YIL173W VTH1 None Golgi_to_vacuole_transport signal_sequence_binding endosome None None 9 11492 16141 YIL173W S000001435 "ORF,_Verified" "Putative_membrane_glycoprotein_with_strong_similarity_to_Vth2p_and_Pep1p/Vps10p,_may_be_involved_in_vacuolar_protein_sorting" YIL174W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 9469 9696 YIL174W S000001436 "pseudogene,_None" Hypothetical_protein YIL175W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 9183 9500 YIL175W S000001437 "pseudogene,_None" Hypothetical_protein YIL177C None None biological_process_unknown helicase_activity cellular_component_unknown G1 None 9 6147 483 YIL177C S000001439 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_similarity_to_DNA_helicases_that_are_encoded_within_subtelomeric_Y'_elements_and_induced_in_telomerase_deficient_survivors YIR001C SGN1 RBP29|RBP1 mRNA_metabolism poly(A)_binding cytoplasm None None 9 356892 356140 YIR001C S000001440 "ORF,_Verified" "Cytoplasmic_RNA-binding_protein,_contains_an_RNA_recognition_motif_(RRM);_may_have_a_role_in_mRNA_translation,_as_suggested_by_genetic_interactions_with_genes_encoding_proteins_involved_in_translational_initiation" YIR002C MPH1 None DNA_repair RNA_helicase_activity* nucleus None None 9 360393 357412 YIR002C S000001441 "ORF,_Verified" "Member_of_the_DEAH_family_of_helicases,_functions_in_an_error-free_DNA_damage_bypass_pathway_that_involves_homologous_recombination,_mutations_confer_a_mutator_phenotype" YIR003W None None biological_process_unknown molecular_function_unknown actin_cytoskeleton None Up 9 360882 362921 YIR003W S000001442 "ORF,_Verified" Protein_of_unknown_function;_may_interact_with_ribosomes;_GFP-fusion_protein_colocalizes_with_Sac1p_to_the_actin_cytoskeleton;_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation) YIR004W DJP1 PAS22|ICS1 protein_import_into_peroxisome_matrix chaperone_binding cytosol None None 9 363218 364516 YIR004W S000001443 "ORF,_Verified" "Cytosolic_J-domain-containing_protein,_required_for_peroxisomal_protein_import_and_involved_in_peroxisome_assembly,_homologous_to_E._coli_DnaJ" YIR005W IST3 SNU17 "nuclear_mRNA_splicing,_via_spliceosome*" "RNA_splicing_factor_activity,_transesterification_mechanism" snRNP_U2 None None 9 364886 365332 YIR005W S000001444 "ORF,_Verified" "Component_of_the_U2_snRNP,_required_for_the_first_catalytic_step_of_splicing_and_for_spliceosomal_assembly;_interacts_with_Rds3p_and_is_required_for_Mer1p-activated_splicing" YIR006C PAN1 DIM2|MIP3|MDP3 endocytosis* "protein_binding,_bridging" plasma_membrane* None None 9 369905 365463 YIR006C S000001445 "ORF,_Verified" "Part_of_actin_cytoskeleton-regulatory_complex_Pan1p-Sla1p-End3p,_associates_with_actin_patches_on_the_cell_cortex;_promotes_protein-protein_interactions_essential_for_endocytosis;_previously_thought_to_be_a_subunit_of_poly(A)_ribonuclease" YIR009W MSL1 YIB9|YIB9w "nuclear_mRNA_splicing,_via_spliceosome" RNA_binding snRNP_U2 None None 9 374522 374857 YIR009W S000001448 "ORF,_Verified" "U2B_component_of_U2_snRNP,_involved_in_splicing,_binds_the_U2_snRNA_stem-loop_IV_in_vitro;_does_not_contain_the_conserved_C-terminal_RNA_binding_domain_found_in_other_family_members" YIR010W DSN1 None chromosome_segregation molecular_function_unknown kinetochore* S/G2 None 9 375428 377158 YIR010W S000001449 "ORF,_Verified" Essential_component_of_the_MIND_kinetochore_complex_(Mtw1p_Including_Nnf1p-Nsl1p-Dsn1p)_which_joins_kinetochore_subunits_contacting_DNA_to_those_contacting_microtubules;_important_for_chromosome_segregation YIR011C STS1 SSM5|DBF8 ubiquitin-dependent_protein_catabolism* molecular_function_unknown nucleus None None 9 378243 377284 YIR011C S000001450 "ORF,_Verified" Protein_that_interacts_with_the_karyopherin_Srp1p;_may_have_a_role_with_Srp1p_in_ubiquitin-mediated_protein_degradation YIR012W SQT1 None ribosomal_large_subunit_assembly_and_maintenance molecular_function_unknown cytoplasm* None None 9 378483 379778 YIR012W S000001451 "ORF,_Verified" Essential_protein_involved_in_a_late_step_of_60S_ribosomal_subunit_assembly_or_modification;_contains_multiple_WD_repeats;_interacts_with_Qsr1p_in_a_two-hybrid_assay YIR014W None None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) None None 9 381083 381811 YIR014W S000001453 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuole;_expression_directly_regulated_by_the_metabolic_and_meiotic_transcriptional_regulator_Ume6p;_YIR014W_is_a_non-essential_gene YIR015W RPR2 None tRNA_processing ribonuclease_P_activity nucleolar_ribonuclease_P_complex None None 9 381945 382379 YIR015W S000001454 "ORF,_Verified" "Subunit_of_nuclear_RNase_P,_which_cleaves_tRNA_precursors_to_generate_mature_5'_ends;_not_shared_between_RNase_MRP_and_RNase_P,_in_contrast_to_all_other_RNase_P_protein_subunits" YIR016W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 382625 383422 YIR016W S000001455 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_expression_directly_regulated_by_the_metabolic_and_meiotic_transcriptional_regulator_Ume6p;_overexpression_causes_a_cell_cycle_delay_or_arrest;_YIR016W_is_a_non-essential_gene YIR017C MET28 None regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus S None 9 384116 383553 YIR017C S000001456 "ORF,_Verified" "Basic_leucine_zipper_(bZIP)_transcriptional_activator_in_the_Cbf1p-Met4p-Met28p_complex,_participates_in_the_regulation_of_sulfur_metabolism" YIR018W YAP5 None positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* RNA_polymerase_II_transcription_factor_activity nucleus None None 9 384606 385343 YIR018W S000001457 "ORF,_Verified" Basic_leucine_zipper_(bZIP)_transcription_factor YIR019C MUC1 STA4|FLO11 pseudohyphal_growth* molecular_function_unknown plasma_membrane None None 9 393672 389569 YIR019C S000001458 "ORF,_Verified" "GPI-anchored_cell_surface_glycoprotein_(flocculin)_required_for_pseudohyphal_formation,_invasive_growth,_flocculation,_and_biofilms;_transcriptionally_regulated_by_the_MAPK_pathway_(via_Ste12p_and_Tec1p)_and_the_cAMP_pathway_(via_Flo8p)" YIR022W SEC11 None signal_peptide_processing signal_peptidase_activity endoplasmic_reticulum* None None 9 398730 399233 YIR022W S000001461 "ORF,_Verified" "18kDa_catalytic_subunit_of_the_Signal_Peptidase_Complex_(SPC;_Spc1p,_Spc2p,_Spc3p,_and_Sec11p)_which_cleaves_the_signal_sequence_of_proteins_targeted_to_the_endoplasmic_reticulum" YIR024C None GIF1 biological_process_unknown molecular_function_unknown mitochondrion None None 9 403488 402838 YIR024C S000001463 "ORF,_Verified" "Protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_interacts_with_Arh1p,_a_mitochondrial_oxidoreductase;_deletion_mutant_has_a_respiratory_growth_defect" YIR025W MND2 None mitotic_sister_chromatid_segregation* molecular_function_unknown nucleus* None Up 9 403656 404762 YIR025W S000001464 "ORF,_Verified" Subunit_of_the_anaphase-promoting_complex_(APC);_necessary_for_maintaining_sister_chromatid_cohesion_in_prophase_I_of_meiosis_by_inhibiting_premature_ubiquitination_and_subsequent_degradation_of_substrates_by_the_APC(Ama1)_ubiquitin_ligase YIR026C YVH1 None sporulation_(sensu_Fungi)* protein_tyrosine_phosphatase_activity* cytoplasm None None 9 405964 404870 YIR026C S000001465 "ORF,_Verified" "Protein_phosphatase_involved_in_vegetative_growth_at_low_temperatures,_sporulation,_and_glycogen_accumulation;_transcription_induced_by_low_temperature_and_nitrogen_starvation;_member_of_the_dual-specificity_family_of_protein_phosphatases" YIR029W DAL2 ALC1 allantoin_catabolism allantoicase_activity cellular_component_unknown None None 9 410804 411835 YIR029W S000001468 "ORF,_Verified" "Allantoicase,_converts_allantoate_to_urea_and_ureidoglycolate_in_the_second_step_of_allantoin_degradation;_expression_sensitive_to_nitrogen_catabolite_repression_and_induced_by_allophanate,_an_intermediate_in_allantoin_degradation" YIR030C DCG1 None nitrogen_compound_metabolism molecular_function_unknown cellular_component_unknown None None 9 412767 412033 YIR030C S000001469 "ORF,_Verified" "Protein_of_unknown_function,_expression_is_sensitive_to_nitrogen_catabolite_repression_and_regulated_by_Dal80p;_contains_transmembrane_domain" YIR032C DAL3 None allantoin_catabolism ureidoglycolate_hydrolase_activity membrane None None 9 415614 415027 YIR032C S000001471 "ORF,_Verified" "Ureidoglycolate_hydrolase,_converts_ureidoglycolate_to_glyoxylate_and_urea_in_the_third_step_of_allantoin_degradation;_expression_sensitive_to_nitrogen_catabolite_repression" YIR033W MGA2 None positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* transcriptional_activator_activity endoplasmic_reticulum_membrane None None 9 416121 419462 YIR033W S000001472 "ORF,_Verified" "ER_membrane_protein_involved_in_regulation_of_OLE1_transcription,_acts_with_homolog_Spt23p;_inactive_ER_form_dimerizes_and_one_subunit_is_then_activated_by_ubiquitin/proteasome-dependent_processing_followed_by_nuclear_targeting" YIR034C LYS1 None lysine_biosynthesis_via_aminoadipic_acid "saccharopine_dehydrogenase_(NAD+,_L-lysine-forming)_activity" cytoplasm* None Up 9 420733 419612 YIR034C S000001473 "ORF,_Verified" "Saccharopine_dehydrogenase_(NAD+,_L-lysine-forming),_catalyzes_the_conversion_of_saccharopine_to_L-lysine,_which_is_the_final_step_in_the_lysine_biosynthesis_pathway" YIR035C None None biological_process_unknown molecular_function_unknown cytoplasm None None 9 421787 421023 YIR035C S000001474 "ORF,_Uncharacterized" Putative_cytoplasmic_protein_of_unknown_function YIR036C IRC24 None biological_process_unknown molecular_function_unknown cytoplasm M/G1 Up 9 422862 422071 YIR036C S000001475 "ORF,_Uncharacterized" Putative_benzil_reductase;(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_is_induced_by_the_DNA-damaging_agent_MMS;_sequence_similarity_with_short-chain_dehydrogenase/reductases;_null_mutant_has_increased_spontaneous_Rad52p_foci YIR037W HYR1 ORP1|GPX3 response_to_oxidative_stress thiol_peroxidase_activity* intracellular None None 9 423125 423616 YIR037W S000001476 "ORF,_Verified" Thiol_peroxidase_that_functions_as_a_hydroperoxide_receptor_to_sense_intracellular_hydroperoxide_levels_and_transduce_a_redox_signal_to_the_Yap1p_transcription_factor YIR042C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 435980 435270 YIR042C S000001481 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YIR042C_is_a_non-essential_gene YIR043C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 437732 437040 YIR043C S000001482 "pseudogene,_None" "Possible_pseudogene_in_strain_S288C;_YIR043C_and_the_adjacent_ORF,_YIR044C,_together_may_encode_a_non-functional_member_of_the_conserved,_often_subtelomerically-encoded_Cos_protein_family" YIR044C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 9 438176 437991 YIR044C S000001483 "pseudogene,_None" "Possible_pseudogene_in_strain_S288C;_YIR044C_and_the_adjacent_ORF,_YIR043C,_together_may_encode_a_non-functional_member_of_the_conserved,_often_subtelomerically-encoded_Cos_protein_family" YJL001W PRE3 CRL21 response_to_stress* endopeptidase_activity "proteasome_core_complex,_beta-subunit_complex_(sensu_Eukaryota)" None Up 10 435156 435919 YJL001W S000003538 "ORF,_Verified" "Beta_1_subunit_of_the_20S_proteasome,_responsible_for_cleavage_after_acidic_residues_in_peptides" YJL003W COX16 None aerobic_respiration* molecular_function_unknown mitochondrial_inner_membrane None None 10 432637 432993 YJL003W S000003540 "ORF,_Verified" "Mitochondrial_inner_membrane_protein,_required_for_assembly_of_cytochrome_c_oxidase" YJL004C SYS1 None Golgi_to_endosome_transport* molecular_function_unknown integral_to_Golgi_membrane* None None 10 432193 431582 YJL004C S000003541 "ORF,_Verified" Integral_membrane_protein_of_the_Golgi_required_for_targeting_of_the_Arf-like_GTPase_Arl3p_to_the_Golgi;_multicopy_suppressor_of_ypt6_null_mutation YJL006C CTK2 None protein_amino_acid_phosphorylation* cyclin-dependent_protein_kinase_regulator_activity nucleus None None 10 424102 423131 YJL006C S000003543 "ORF,_Verified" "Beta_subunit_of_C-terminal_domain_kinase_I_(CTDK-I),_which_phosphorylates_both_RNA_pol_II_subunit_Rpo21p_to_affect_transcription_and_pre-mRNA_3'_end_processing,_and_ribosomal_protein_Rps2p_to_increase_translational_fidelity" YJL010C NOP9 None rRNA_processing RNA_binding nucleus* None None 10 419555 417555 YJL010C S000003547 "ORF,_Verified" Essential_component_of_pre-40S_ribosomes_that_is_required_for_early_cleavages_of_35S_pre-rRNA_and_hence_formation_of_18S_rRNA;_binds_RNA_in_vitro_and_contains_multiple_pumilio-like_repeats YJL011C RPC17 None transcription_initiation_from_RNA_polymerase_III_promoter DNA-directed_RNA_polymerase_activity DNA-directed_RNA_polymerase_III_complex None None 10 414763 414278 YJL011C S000003548 "ORF,_Verified" "RNA_polymerase_III_subunit_C17;_physically_interacts_with_C31,_C11,_and_TFIIIB70;_may_be_involved_in_the_recruitment_of_pol_III_by_the_preinitiation_complex" YJL019W MPS3 YJL018W|NEP98 mitotic_sister_chromatid_cohesion* molecular_function_unknown integral_to_membrane* G1 None 10 402891 404939 YJL019W S000003556 "ORF,_Verified" Nuclear_envelope_protein_required_for_SPB_duplication_and_nuclear_fusion;_localizes_to_the_SPB_half_bridge_and_at_telomeres_during_meiosis;_required_with_Ndj1p_and_Csm4p_for_meiotic_bouquet_formation_and_telomere-led_rapid_prophase_movement YJL023C PET130 None biological_process_unknown molecular_function_unknown mitochondrion None None 10 398392 397349 YJL023C S000003560 "ORF,_Verified" "Protein_required_for_respiratory_growth;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YJL024C APS3 YKS7 vesicle-mediated_transport* molecular_function_unknown AP-3_adaptor_complex None None 10 396586 395925 YJL024C S000003561 "ORF,_Verified" "Small_subunit_of_the_clathrin-associated_adaptor_complex_AP-3,_which_is_involved_in_vacuolar_protein_sorting;_related_to_the_sigma_subunit_of_the_mammalian_clathrin_AP-3_complex;_suppressor_of_loss_of_casein_kinase_1_function" YJL025W RRN7 None transcription_from_RNA_polymerase_I_promoter RNA_polymerase_I_transcription_factor_activity RNA_polymerase_I_transcription_factor_complex None None 10 393961 395505 YJL025W S000003562 "ORF,_Verified" "Protein_involved_in_the_transcription_of_35S_rRNA_genes_by_RNA_polymerase_I;_component_of_the_core_factor_(CF)_complex_also_composed_of_Rrn11p,_Rrn6p_and_TATA-binding_protein" YJL027C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 392243 391827 YJL027C S000003564 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YJL028W None None None None None None None 10 391305 391640 YJL028W S000003565 "ORF,_Verified" "Protein_of_unknown_function;_may_interact_with_ribosomes,_based_on_co-purification_experiments" YJL030W MAD2 None mitotic_spindle_checkpoint molecular_function_unknown nuclear_pore* None Up 10 387651 388241 YJL030W S000003567 "ORF,_Verified" "Component_of_the_spindle-assembly_checkpoint_complex,_which_delays_the_onset_of_anaphase_in_cells_with_defects_in_mitotic_spindle_assembly;_forms_a_complex_with_Mad1p" YJL031C BET4 None protein_amino_acid_geranylgeranylation Rab-protein_geranylgeranyltransferase_activity Rab-protein_geranylgeranyltransferase_complex None Up 10 387432 386362 YJL031C S000003568 "ORF,_Verified" Alpha_subunit_of_Type_II_geranylgeranyltransferase_required_for_vesicular_transport_between_the_endoplasmic_reticulum_and_the_Golgi;_provides_a_membrane_attachment_moiety_to_Rab-like_proteins_Ypt1p_and_Sec4p YJL033W HCA4 ECM24|DBP4 35S_primary_transcript_processing ATP-dependent_RNA_helicase_activity nucleolus None None 10 383831 386143 YJL033W S000003570 "ORF,_Verified" Putative_nucleolar_DEAD_box_RNA_helicase;_high-copy_number_suppression_of_a_U14_snoRNA_processing_mutant_suggests_an_involvement_in_18S_rRNA_synthesis YJL034W KAR2 GRP78 "SRP-dependent_cotranslational_protein_targeting_to_membrane,_translocation*" ATPase_activity* endoplasmic_reticulum_lumen None None 10 381321 383369 YJL034W S000003571 "ORF,_Verified" "ATPase_involved_in_protein_import_into_the_ER,_also_acts_as_a_chaperone_to_mediate_protein_folding_in_the_ER_and_may_play_a_role_in_ER_export_of_soluble_proteins;_regulates_the_unfolded_protein_response_via_interaction_with_Ire1p" YJL036W SNX4 ATG24|CVT13 transport* lipid_binding membrane None None 10 378819 380090 YJL036W S000003573 "ORF,_Verified" "Sorting_nexin,_involved_in_retrieval_of_late-Golgi_SNAREs_from_post-Golgi_endosomes_to_the_trans-Golgi_network_and_in_cytoplasm_to_vacuole_transport;_contains_a_PX_phosphoinositide-binding_domain;_forms_complexes_with_Snx41p_and_with_Atg20p" YJL038C LOH1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 375768 375109 YJL038C S000003575 "ORF,_Verified" Protein_of_unknown_function_with_proposed_role_in_maintenance_of_genome_integrity;_deletion_mutant_displays_elevated_rates_of_LOH;_induced_during_sporulation;_repressed_during_vegetative_growth_by_Sum1p_and_Hst1p;_sequence_similar_to_IRC1 YJL041W NSP1 None mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None Up 10 365778 368367 YJL041W S000003577 "ORF,_Verified" "Essential_component_of_the_nuclear_pore_complex,_which_mediates_nuclear_import_and_export" YJL042W MHP1 None cell_wall_organization_and_biogenesis* structural_constituent_of_cytoskeleton microtubule None None 10 361243 365439 YJL042W S000003578 "ORF,_Verified" Microtubule-associated_protein_involved_in_assembly_and_stabilization_of_microtubules;_overproduction_results_in_cell_cycle_arrest_at_G2_phase;_similar_to_Drosophila_protein_MAP_and_to_mammalian_MAP4_proteins YJL043W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 10 360124 360897 YJL043W S000003579 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YJL043W_is_a_non-essential_gene YJL044C GYP6 None intracellular_protein_transport GTPase_activator_activity endosome* M/G1 None 10 359670 358294 YJL044C S000003580 "ORF,_Verified" "GTPase-activating_protein_(GAP)_for_the_yeast_Rab_family_member,_Ypt6p;_involved_in_vesicle_mediated_protein_transport" YJL045W None SDH1b cellular_respiration succinate_dehydrogenase_(ubiquinone)_activity mitochondrion None None 10 356018 357922 YJL045W S000003581 "ORF,_Uncharacterized" "Minor_succinate_dehydrogenase_isozyme;_homologous_to_Sdh1p,_the_major_isozyme_reponsible_for_the_oxidation_of_succinate_and_transfer_of_electrons_to_ubiquinone;_induced_during_the_diauxic_shift_in_a_Cat8p-dependent_manner" YJL048C UBX6 CUI2 ubiquitin-dependent_protein_catabolism* molecular_function_unknown nucleus None None 10 348631 347441 YJL048C S000003584 "ORF,_Verified" "UBX_(ubiquitin_regulatory_X)_domain-containing_protein_that_interacts_with_Cdc48p,_transcription_is_repressed_when_cells_are_grown_in_media_containing_inositol_and_choline" YJL049W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 345967 347319 YJL049W S000003585 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YJL049W_is_a_non-essential_gene YJL050W MTR4 DOB1 35S_primary_transcript_processing* ATP-dependent_RNA_helicase_activity nucleus* None None 10 342516 345737 YJL050W S000003586 "ORF,_Verified" "Dead-box_family_ATP_dependent_helicase_required_for_mRNA_export_from_the_nucleus;_co-factor_of_the_exosome_complex,_required_for_3'_end_formation_of_5.8S_rRNA" YJL051W IRC8 None biological_process_unknown molecular_function_unknown bud_tip G2/M None 10 339781 342249 YJL051W S000003587 "ORF,_Verified" "Bud_tip_localized_protein_of_unknown_function;_mRNA_is_targeted_to_the_bud_by_a_She2p_dependent_transport_system;_mRNA_is_cell_cycle_regulated_via_Fkh2p,_peaking_in_G2/M_phase;_null_mutant_displays_increased_levels_of_spontaneous_Rad52p_foc" YJL052W TDH1 GLD3 glycolysis* glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating)_activity cytoplasm* None None 10 338265 339263 YJL052W S000003588 "ORF,_Verified" "Glyceraldehyde-3-phosphate_dehydrogenase,_isozyme_1,_involved_in_glycolysis_and_gluconeogenesis;_tetramer_that_catalyzes_the_reaction_of_glyceraldehyde-3-phosphate_to_1,3_bis-phosphoglycerate;_detected_in_the_cytoplasm_and_cell-wall" YJL053W PEP8 VPT4|VPS26|GRD6 protein_retention_in_Golgi* molecular_function_unknown endosome* None None 10 335892 337031 YJL053W S000003589 "ORF,_Verified" "Vacuolar_protein_sorting_protein_that_forms_part_of_the_multimeric_membrane-associated_retromer_complex_along_with_Vps35p,_Vps29p,_Vps17p,_and_Vps5p;_essential_for_endosome-to-Golgi_retrograde_protein_transport" YJL054W TIM54 None protein_import_into_mitochondrial_inner_membrane protein_transporter_activity mitochondrial_inner_membrane_protein_insertion_complex None None 10 334259 335695 YJL054W S000003590 "ORF,_Verified" Component_of_the_mitochondrial_Tim54p-Tim22p_complex_involved_in_insertion_of_polytopic_proteins_into_the_inner_membrane YJL055W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 10 333351 334088 YJL055W S000003591 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_proposed_to_be_involved_in_the_metabolism_of_purine_and_pyrimidine_base_analogues;_deletion_mutants_are_sensitive_to_HAP_and_AHA;_overexpression_confers_resistance_to_5-FOA_and_5-FU" YJL056C ZAP1 ZRG10 regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus None None 10 333067 330425 YJL056C S000003592 "ORF,_Verified" "Zinc-regulated_transcription_factor,_binds_to_zinc-responsive_promoter_elements_to_induce_transcription_of_certain_genes_in_the_presence_of_zinc;_regulates_its_own_transcription;_contains_seven_zinc-finger_domains" YJL060W BNA3 None NAD_biosynthesis arylformamidase_activity cytoplasm* S/G2 Up 10 323380 324714 YJL060W S000003596 "ORF,_Verified" "Kynurenine_aminotransferase,_catalyzes_formation_of_kynurenic_acid_from_kynurenine;_potential_Cdc28p_substrate" YJL061W NUP82 HRB187 mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 10 320010 322151 YJL061W S000003597 "ORF,_Verified" "Nucleoporin,_subunit_of_the_nuclear_pore_complex_(NPC);_forms_a_subcomplex_with_Nup159p_and_Nsp1p,_interacts_with_Nup116p_and_is_required_for_proper_localization_of_Nup116p_in_the_NPC" YJL063C MRPL8 HRD238 protein_biosynthesis* structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 10 316469 315753 YJL063C S000003599 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YJL065C DLS1 None chromatin_silencing_at_telomere molecular_function_unknown nucleus* None None 10 315551 315048 YJL065C S000003601 "ORF,_Verified" "Subunit_of_ISW2/yCHRAC_chromatin_accessibility_complex_along_with_Itc1p,_Isw2p,_and_Dpb4p;_involved_in_inheritance_of_telomeric_silencing" YJL066C MPM1 None biological_process_unknown molecular_function_unknown mitochondrion* None None 10 314866 314108 YJL066C S000003602 "ORF,_Verified" "Mitochondrial_membrane_protein_of_unknown_function,_contains_no_hydrophobic_stretches" YJL069C UTP18 None 35S_primary_transcript_processing molecular_function_unknown nucleolus* None None 10 312700 310916 YJL069C S000003605 "ORF,_Verified" "Possible_U3_snoRNP_protein_involved_in_maturation_of_pre-18S_rRNA,_based_on_computational_analysis_of_large-scale_protein-protein_interaction_data" YJL070C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 10 310631 307965 YJL070C S000003606 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function_with_similarity_to_AMP_deaminases;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_YJL070C_is_a_non-essential_gene" YJL071W ARG2 HRB574 arginine_biosynthesis* amino-acid_N-acetyltransferase_activity mitochondrial_matrix None None 10 306126 307850 YJL071W S000003607 "ORF,_Verified" "Acetylglutamate_synthase_(glutamate_N-acetyltransferase),_mitochondrial_enzyme_that_catalyzes_the_first_step_in_the_biosynthesis_of_the_arginine_precursor_ornithine;_forms_a_complex_with_Arg5,6p" YJL072C PSF2 CDC102 DNA-dependent_DNA_replication molecular_function_unknown nucleus* G1 None 10 305856 305215 YJL072C S000003608 "ORF,_Verified" "Subunit_of_the_GINS_complex_(Sld5p,_Psf1p,_Psf2p,_Psf3p),_which_is_localized_to_DNA_replication_origins_and_implicated_in_assembly_of_the_DNA_replication_machinery" YJL073W JEM1 KAR8 protein_folding* unfolded_protein_binding* endoplasmic_reticulum* G1 None 10 303175 305112 YJL073W S000003609 "ORF,_Verified" "DnaJ-like_chaperone_required_for_nuclear_membrane_fusion_during_mating,_localizes_to_the_ER_membrane;_exhibits_genetic_interactions_with_KAR2" YJL074C SMC3 None sporulation_(sensu_Fungi)* ATPase_activity nucleus* G1 None 10 302843 299151 YJL074C S000003610 "ORF,_Verified" "Subunit_of_the_multiprotein_cohesin_complex_required_for_sister_chromatid_cohesion_in_mitotic_cells;_also_required,_with_Rec8p,_for_cohesion_and_recombination_during_meiosis;_phylogenetically_conserved_SMC_chromosomal_ATPase_family_member" YJL076W NET1 SRM8|CFI1|ESC5 regulation_of_exit_from_mitosis* rDNA_binding nucleolus* None None 10 295239 298808 YJL076W S000003612 "ORF,_Verified" "Core_subunit_of_the_RENT_complex,_which_is_a_complex_involved_in_nucleolar_silencing_and_telophase_exit;_stimulates_transcription_by_RNA_polymerase_I_and_regulates_nucleolar_structure" YJL077C ICS3 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 295055 294660 YJL077C S000003613 "ORF,_Verified" Protein_of_unknown_function YJL078C PRY3 None biological_process_unknown molecular_function_unknown cell_wall_(sensu_Fungi) G1 None 10 293975 291330 YJL078C S000003614 "ORF,_Verified" "Protein_of_unknown_function,_has_similarity_to_Pry1p_and_Pry2p_and_to_the_plant_PR-1_class_of_pathogen_related_proteins" YJL079C PRY1 None biological_process_unknown molecular_function_unknown endoplasmic_reticulum* G2/M None 10 290768 289869 YJL079C S000003615 "ORF,_Verified" "Protein_of_unknown_function,_has_similarity_to_Pry2p_and_Pry3p_and_to_the_plant_PR-1_class_of_pathogen_related_proteins" YJL080C SCP160 None chromosome_segregation* RNA_binding endoplasmic_reticulum_membrane* None None 10 289220 285552 YJL080C S000003616 "ORF,_Verified" "Essential_RNA-binding_G_protein_effector_of_mating_response_pathway,_mainly_associated_with_nuclear_envelope_and_ER,_interacts_in_mRNA-dependent_manner_with_translating_ribosomes_via_multiple_KH_domains,_similar_to_vertebrate_vigilins" YJL088W ARG3 None arginine_biosynthesis* ornithine_carbamoyltransferase_activity cytosol None Up 10 268793 269809 YJL088W S000003624 "ORF,_Verified" "Ornithine_carbamoyltransferase_(carbamoylphosphate:L-ornithine_carbamoyltransferase),_catalyzes_the_sixth_step_in_the_biosynthesis_of_the_arginine_precursor_ornithine" YJL092W SRS2 HPR5|RADH1|RADH DNA_repair* DNA_helicase_activity nucleus G1 None 10 257417 260941 YJL092W S000003628 "ORF,_Verified" "DNA_helicase_and_DNA-dependent_ATPase_involved_in_DNA_repair,_needed_for_proper_timing_of_commitment_to_meiotic_recombination_and_transition_from_Meiosis_I_to_II;_affects_genome_stability_by_suppressing_unscheduled_homologous_recombination" YJL093C TOK1 YPK1|YORK|YKC1|DUK1 potassium_ion_homeostasis potassium_channel_activity plasma_membrane None None 10 256806 254731 YJL093C S000003629 "ORF,_Verified" "Outward-rectifier_potassium_channel_of_the_plasma_membrane_with_two_pore_domains_in_tandem,_each_of_which_forms_a_functional_channel_permeable_to_potassium;_carboxy_tail_functions_to_prevent_inner_gate_closures;_target_of_K1_toxin" YJL094C KHA1 None monovalent_inorganic_cation_transport potassium:hydrogen_antiporter_activity mitochondrion* None None 10 254436 251815 YJL094C S000003630 "ORF,_Verified" "Putative_K+/H+_antiporter_with_a_probable_role_in_intracellular_cation_homeostasis,_localized_to_Golgi_vesicles_and_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YJL095W BCK1 SSP31|SLK1|SAP3|LAS3 protein_amino_acid_phosphorylation* MAP_kinase_kinase_kinase_activity intracellular None None 10 247249 251685 YJL095W S000003631 "ORF,_Verified" "Mitogen-activated_protein_(MAP)_kinase_kinase_kinase_acting_in_the_protein_kinase_C_signaling_pathway,_which_controls_cell_integrity;_upon_activation_by_Pkc1p_phosphorylates_downstream_kinases_Mkk1p_and_Mkk2p" YJL096W MRPL49 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 10 246485 246970 YJL096W S000003632 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YJL097W PHS1 None biological_process_unknown molecular_function_unknown endoplasmic_reticulum* None None 10 245586 246239 YJL097W S000003633 "ORF,_Verified" "Essential_3-hydroxyacyl-CoA_dehydratase_of_the_ER_membrane,_involved_in_elongation_of_very_long-chain_fatty_acids;_evolutionarily_conserved,_similar_to_mammalian_PTPLA_and_PTPLB;_involved_in_sphingolipid_biosynthesis_and_protein_trafficking" YJL098W SAP185 None G1/S_transition_of_mitotic_cell_cycle protein_serine/threonine_phosphatase_activity cytoplasm* None None 10 242077 245253 YJL098W S000003634 "ORF,_Verified" "Protein_that_forms_a_complex_with_the_Sit4p_protein_phosphatase_and_is_required_for_its_function;_member_of_a_family_of_similar_proteins_including_Sap4p,_Sap155p,_and_Sap190p" YJL099W CHS6 CSD3 Golgi_to_plasma_membrane_transport* molecular_function_unknown clathrin-coated_vesicle S/G2 Up 10 239409 241649 YJL099W S000003635 "ORF,_Verified" "Member_of_the_ChAPs_family_of_proteins_(Chs5p-Arf1p-binding_proteins:_Bch1p,_Bch2p,_Bud7p,_Chs6p),_that_forms_the_exomer_complex_with_Chs5p_to_mediate_export_of_specific_cargo_proteins,_including_Chs3p,_from_the_Golgi_to_the_plasma_membrane" YJL100W LSB6 None actin_filament_organization* 1-phosphatidylinositol_4-kinase_activity cytoplasm* None None 10 237258 239081 YJL100W S000003636 "ORF,_Verified" "Type_II_phosphatidylinositol_4-kinase_that_binds_Las17p,_which_is_a_homolog_of_human_Wiskott-Aldrich_Syndrome_protein_involved_in_actin_patch_assembly_and_actin_polymerization" YJL101C GSH1 None response_to_cadmium_ion* glutamate-cysteine_ligase_activity intracellular None None 10 236351 234315 YJL101C S000003637 "ORF,_Verified" "Gamma_glutamylcysteine_synthetase_catalyzes_the_first_step_in_glutathione_(GSH)_biosynthesis;_expression_induced_by_oxidants,_cadmium,_and_mercury" YJL102W MEF2 None translational_elongation translation_elongation_factor_activity mitochondrion None None 10 231296 233755 YJL102W S000003638 "ORF,_Verified" Mitochondrial_elongation_factor_involved_in_translational_elongation YJL104W PAM16 TIM16|MIA1 protein_import_into_mitochondrial_matrix protein_binding* mitochondrion* None None 10 227322 227771 YJL104W S000003640 "ORF,_Verified" "Constituent_of_the_mitochondrial_import_motor_associated_with_the_presequence_translocase,_along_with_Ssc1p,_Tim44p,_Mge1p,_and_Pam18p;_forms_a_1:1_subcomplex_with_Pam18p_and_inhibits_its_cochaperone_activity;_contains_J-like_domain" YJL108C PRM10 None conjugation_with_cellular_fusion molecular_function_unknown integral_to_membrane None None 10 218851 217700 YJL108C S000003644 "ORF,_Verified" "Pheromone-regulated_protein,_predicted_to_have_5_transmembrane_segments;_induced_by_treatment_with_8-methoxypsoralen_and_UVA_irradiation" YJL110C GZF3 NIL2|DEH1 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_factor_activity* nucleus None None 10 211572 209917 YJL110C S000003646 "ORF,_Verified" GATA_zinc_finger_protein_and_Dal80p_homolog_that_negatively_regulates_nitrogen_catabolic_gene_expression_by_competing_with_Gat1p_for_GATA_site_binding;_function_requires_a_repressive_carbon_source;_dimerizes_with_Dal80p_and_binds_to_Tor1p YJL114W None None None None None None None 10 197912 199156 YJL114W S000003650 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YJL115W ASF1 CIA1 "DNA_damage_response,_signal_transduction_resulting_in_induction_of_apoptosis" transcription_regulator_activity* chromatin_assembly_complex G1 None 10 196284 197123 YJL115W S000003651 "ORF,_Verified" "Nucleosome_assembly_factor,_involved_in_chromatin_assembly_and_disassembly,_anti-silencing_protein_that_causes_derepression_of_silent_loci_when_overexpressed;_plays_a_role_in_regulating_Ty1_transposition" YJL117W PHO86 None protein_folding* molecular_function_unknown endoplasmic_reticulum None None 10 192529 193464 YJL117W S000003653 "ORF,_Verified" "Endoplasmic_reticulum_(ER)_resident_protein_required_for_ER_exit_of_the_high-affinity_phosphate_transporter_Pho84p,_specifically_required_for_packaging_of_Pho84p_into_COPII_vesicles" YJL118W None None biological_process_unknown molecular_function_unknown cellular_component_unknown S None 10 191637 192296 YJL118W S000003654 "ORF,_Verified" "Putative_protein_of_unknown_function;_may_interact_with_ribosomes,_based_on_co-purification_experiments;_YJL18W_is_a_non-essential_gene;_deletion_enhances_the_toxicity_of_heterologously_expressed_human_alpha-synuclein" YJL121C RPE1 POS18|EPI1 pentose-phosphate_shunt ribulose-phosphate_3-epimerase_activity cytosol None Down 10 191088 190372 YJL121C S000003657 "ORF,_Verified" "D-ribulose-5-phosphate_3-epimerase,_catalyzes_a_reaction_in_the_non-oxidative_part_of_the_pentose-phosphate_pathway;_mutants_are_sensitive_to_oxidative_stress" YJL122W ALB1 None biological_process_unknown molecular_function_unknown nucleus None Down 10 189714 190241 YJL122W S000003658 "ORF,_Verified" Shuttling_pre-60S_factor;_involved_in_the_biogenesis_of_ribosomal_large_subunit;_interacts_directly_with_Arx1p;_responsible_for_Tif6p_recycling_defects_in_absence_of_Rei1p YJL123C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 10 189438 188002 YJL123C S000003659 "ORF,_Verified" Protein_of_unknown_function_that_may_interact_with_ribosomes;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_to_COPI-coated_vesicles_(early_Golgi);_YJL123C_is_synthetically_lethal_with_cdc13-1 YJL125C GCD14 TRM61 tRNA_methylation tRNA_(adenine-N1-)-methyltransferase_activity nucleus None None 10 186676 185525 YJL125C S000003661 "ORF,_Verified" "Subunit_of_tRNA_(1-methyladenosine)_methyltransferase,_with_Gcd10p,_required_for_the_modification_of_the_adenine_at_position_58_in_tRNAs,_especially_tRNAi-Met;_first_identified_as_a_negative_regulator_of_GCN4_expression" YJL126W NIT2 None biological_process_unknown "hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds" cellular_component_unknown None None 10 184498 185421 YJL126W S000003662 "ORF,_Verified" "Nit_protein,_one_of_two_proteins_in_S._cerevisiae_with_similarity_to_the_Nit_domain_of_NitFhit_from_fly_and_worm_and_to_the_mouse_and_human_Nit_protein_which_interacts_with_the_Fhit_tumor_suppressor;_nitrilase_superfamily_member" YJL127C SPT10 SUD1|CRE1 chromatin_remodeling* histone_acetyltransferase_activity nucleus None None 10 184217 182295 YJL127C S000003663 "ORF,_Verified" "Putative_histone_acetylase,_sequence-specific_activator_of_histone_genes,_binds_specifically_and_highly_cooperatively_to_pairs_of_UAS_elements_in_core_histone_promoters,_functions_at_or_near_the_TATA_box" YJL128C PBS2 SSK4|SFS4|HOG4 protein_amino_acid_phosphorylation* MAP_kinase_kinase_activity* cytoplasm None None 10 180099 178093 YJL128C S000003664 "ORF,_Verified" "MAP_kinase_kinase_that_plays_a_pivotal_role_in_the_osmosensing_signal-transduction_pathway,_activated_under_severe_osmotic_stress;_plays_a_role_in_regulating_Ty1_transposition" YJL130C URA2 None de_novo'_pyrimidine_base_biosynthesis* aspartate_carbamoyltransferase_activity cytoplasm* None None 10 172363 165719 YJL130C S000003666 "ORF,_Verified" "Bifunctional_carbamoylphosphate_synthetase_(CPSase)-aspartate_transcarbamylase_(ATCase),_catalyzes_the_first_two_enzymatic_steps_in_the_de_novo_biosynthesis_of_pyrimidines;_both_activities_are_subject_to_feedback_inhibition_by_UTP" YJL131C None None biological_process_unknown molecular_function_unknown mitochondrion None None 10 165344 164274 YJL131C S000003667 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic_non-tagged_protein_is_detected_in_highly_purified_mitochondria;_null_mutant_is_viable,_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation)" YJL132W None None biological_process_unknown molecular_function_unknown membrane_fraction None None 10 161910 164162 YJL132W S000003668 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_localizes_to_the_membrane_fraction;_possible_Zap1p-regulated_target_gene_induced_by_zinc_deficiency;_YJL132W_is_a_non-essential_gene YJL133W MRS3 None RNA_splicing* iron_ion_transporter_activity* mitochondrion None None 10 160615 161559 YJL133W S000003669 "ORF,_Verified" "Mitochondrial_iron_transporter_of_the_mitochondrial_carrier_family_(MCF),_very_similar_to_and_functionally_redundant_with_Mrs4p;_functions_under_low-iron_conditions;_may_transport_other_cations_in_addition_to_iron" YJL134W LCB3 YSR2|LBP1 sphingolipid_biosynthesis* sphingosine-1-phosphate_phosphatase_activity endoplasmic_reticulum S/G2 None 10 158184 159413 YJL134W S000003670 "ORF,_Verified" "Long-chain_base-1-phosphate_phosphatase_with_specificity_for_dihydrosphingosine-1-phosphate,_regulates_ceramide_and_long-chain_base_phosphates_levels,_involved_in_incorporation_of_exogenous_long_chain_bases_in_sphingolipids" YJL136C RPS21B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 10 157269 156546 YJL136C S000003672 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps21Ap_and_has_similarity_to_rat_S21_ribosomal_protein YJL138C TIF2 None translational_initiation* translation_initiation_factor_activity* cytoplasm* None None 10 154687 153500 YJL138C S000003674 "ORF,_Verified" "Translation_initiation_factor_eIF4A,_identical_to_Tif1p;_DEA(D/H)-box_RNA_helicase_that_couples_ATPase_activity_to_RNA_binding_and_unwinding;_forms_a_dumbbell_structure_of_two_compact_domains_connected_by_a_linker;_interacts_with_eIF4G" YJL140W RPB4 CTF15 mRNA_export_from_nucleus* DNA-directed_RNA_polymerase_activity cytoplasm* None None 10 150957 151622 YJL140W S000003676 "ORF,_Verified" RNA_polymerase_II_subunit_B32;_forms_two_subunit_dissociable_complex_with_Rpb7p;_involved_recruitment_of_3'-end_processing_factors_to_transcribing_RNA_polymerase_II_complex_and_in_export_of_mRNA_to_cytoplasm_under_stress_conditions YJL141C YAK1 None protein_amino_acid_phosphorylation protein_kinase_activity cytoplasm* None None 10 150386 147963 YJL141C S000003677 "ORF,_Verified" Serine-threonine_protein_kinase_that_is_part_of_a_glucose-sensing_system_involved_in_growth_control_in_response_to_glucose_availability;_translocates_from_the_cytoplasm_to_the_nucleus_and_phosphorylates_Pop2p_in_response_to_a_glucose_signal YJL143W TIM17 SMS1|MPI2|MIM17 protein_import_into_mitochondrial_matrix protein_transporter_activity mitochondrial_inner_membrane_presequence_translocase_complex None None 10 147097 147573 YJL143W S000003679 "ORF,_Verified" Essential_constituent_of_the_mitochondrial_inner_membrane_presequence_translocase;_interacts_with_Pam18p_to_recruit_the_presequence_translocase-associated_motor_(PAM_complex)_and_also_required_for_protein_sorting_during_import YJL144W None None response_to_desiccation molecular_function_unknown cytoplasm None None 10 146355 146669 YJL144W S000003680 "ORF,_Uncharacterized" "Cytoplasmic_hydrophilin_of_unknown_function,_possibly_involved_in_the_dessication_response;_expression_induced_by_osmotic_stress,_starvation_and_during_stationary_phase;_GFP-fusion_protein_is_induced_by_the_DNA-damaging_agent_MMS" YJL145W SFH5 None phospholipid_transport phosphatidylinositol_transporter_activity cytosol* None None 10 145156 146040 YJL145W S000003681 "ORF,_Verified" "Putative_phosphatidylinositol_transfer_protein_(PITP),_exhibits_phosphatidylinositol-_but_not_phosphatidylcholine-transfer_activity,_localized_to_cytosol_and_microsomes,_similar_to_Sec14p;_may_be_PITP_regulator_rather_than_actual_PITP" YJL146W IDS2 None meiosis molecular_function_unknown cytoplasm* None None 10 143288 144697 YJL146W S000003682 "ORF,_Verified" "Protein_involved_in_modulation_of_Ime2p_activity_during_meiosis,_appears_to_act_indirectly_to_promote_Ime2p-mediated_late_meiotic_functions;_found_in_growing_cells_and_degraded_during_sporulation" YJL148W RPA34 None transcription_from_RNA_polymerase_I_promoter DNA-directed_RNA_polymerase_activity nucleus* None None 10 140433 141134 YJL148W S000003684 "ORF,_Verified" RNA_polymerase_I_subunit_A34.5 YJL149W None None biological_process_unknown molecular_function_unknown SCF_ubiquitin_ligase_complex None None 10 137375 139366 YJL149W S000003685 "ORF,_Verified" Putative_SCF_ubiquitin_ligase_F-box_protein;_interacts_physically_with_both_Cdc53p_and_Skp1_and_genetically_with_CDC34;_similar_to_putative_F-box_protein_YDR131C;_null_mutant_suppresses_dst1delta_sensitivity_for_6-azauracil YJL151C SNA3 None biological_process_unknown molecular_function_unknown membrane* None None 10 136769 136368 YJL151C S000003687 "ORF,_Verified" "Integral_membrane_protein_localized_to_vacuolar_intralumenal_vesicles,_computational_analysis_of_large-scale_protein-protein_interaction_data_suggests_a_possible_role_in_either_cell_wall_synthesis_or_protein-vacuolar_targeting" YJL153C INO1 38077 myo-inositol_metabolism inositol-3-phosphate_synthase_activity cytoplasm None None 10 135929 134328 YJL153C S000003689 "ORF,_Verified" "Inositol_1-phosphate_synthase,_involved_in_synthesis_of_inositol_phosphates_and_inositol-containing_phospholipids;_transcription_is_coregulated_with_other_phospholipid_biosynthetic_genes_by_Ino2p_and_Ino4p,_which_bind_the_UASINO_DNA_element" YJL154C VPS35 VPT7|GRD9 protein_retention_in_Golgi* molecular_function_unknown endosome* None Up 10 133931 131097 YJL154C S000003690 "ORF,_Verified" "Endosomal_subunit_of_membrane-associated_retromer_complex_required_for_retrograde_transport;_receptor_that_recognizes_retrieval_signals_on_cargo_proteins,_forms_subcomplex_with_Vps26p_and_Vps29p_that_selects_cargo_proteins_for_retrieval" YJL155C FBP26 None glucose_metabolism "fructose-2,6-bisphosphate_2-phosphatase_activity*" cytosol None None 10 130639 129281 YJL155C S000003691 "ORF,_Verified" "Fructose-2,6-bisphosphatase,_required_for_glucose_metabolism" YJL156C SSY5 None sensory_perception_of_chemical_stimulus amino_acid_binding extrinsic_to_plasma_membrane None None 10 128948 126849 YJL156C S000003692 "ORF,_Verified" "Probable_serine_protease_of_the_SPS_plasma_membrane_amino_acid_sensor_system_(Ssy1p-Ptr3p-Ssy5p),_which_senses_external_amino_acid_concentration_and_transmits_intracellular_signals_that_regulate_expression_of_amino_acid_permease_genes" YJL158C CIS3 CCW5|PIR4|CCW11 cell_wall_organization_and_biogenesis structural_constituent_of_cell_wall endoplasmic_reticulum* S/G2 None 10 122944 122261 YJL158C S000003694 "ORF,_Verified" Mannose-containing_glycoprotein_constituent_of_the_cell_wall;_member_of_the_PIR_(proteins_with_internal_repeats)_family YJL159W HSP150 PIR2|ORE1|CCW7 cell_wall_organization_and_biogenesis structural_constituent_of_cell_wall cell_wall_(sensu_Fungi) M/G1 None 10 120445 121686 YJL159W S000003695 "ORF,_Verified" "O-mannosylated_heat_shock_protein_that_is_secreted_and_covalently_attached_to_the_cell_wall_via_beta-1,3-glucan_and_disulfide_bridges;_required_for_cell_wall_stability;_induced_by_heat_shock,_oxidative_stress,_and_nitrogen_limitation" YJL161W None None biological_process_unknown molecular_function_unknown mitochondrion None Up 10 117241 117783 YJL161W S000003697 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YJL162C JJJ2 None biological_process_unknown molecular_function_unknown cytoplasm* None None 10 115625 113874 YJL162C S000003698 "ORF,_Verified" "Protein_of_unknown_function,_contains_a_J-domain,_which_is_a_region_with_homology_to_the_E._coli_DnaJ_protein" YJL163C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 113329 111662 YJL163C S000003699 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YJL166W QCR8 COR5 aerobic_respiration* ubiquinol-cytochrome-c_reductase_activity respiratory_chain_complex_III_(sensu_Eukaryota) None None 10 106428 106712 YJL166W S000003702 "ORF,_Verified" "Subunit_8_of_ubiquinol_cytochrome-c_reductase_complex,_which_is_a_component_of_the_mitochondrial_inner_membrane_electron_transport_chain;_oriented_facing_the_intermembrane_space;_expression_is_regulated_by_Abf1p_and_Cpf1p" YJL168C SET2 EZL1 "regulation_of_transcription,_DNA-dependent*" histone_methyltransferase_activity* nucleus None None 10 104422 102221 YJL168C S000003704 "ORF,_Verified" "Histone_methyltransferase_with_a_role_in_transcriptional_elongation,_methylates_a_lysine_residue_of_histone_H3;_associates_with_the_C-terminal_domain_of_Rpo21p;_histone_methylation_activity_is_regulated_by_phosphorylation_status_of_Rpo21p" YJL170C ASG7 None conjugation_with_cellular_fusion molecular_function_unknown plasma_membrane None None 10 101773 101144 YJL170C S000003706 "ORF,_Verified" Protein_that_regulates_signaling_from_a_G_protein_beta_subunit_Ste4p_and_its_relocalization_within_the_cell;_specific_to_a-cells_and_induced_by_alpha-factor YJL172W CPS1 None proteolysis* Gly-X_carboxypeptidase_activity vacuole_(sensu_Fungi) None Up 10 97731 99461 YJL172W S000003708 "ORF,_Verified" Vacuolar_carboxypeptidase_yscS;_expression_is_induced_under_low-nitrogen_conditions YJL173C RFA3 RPA3 DNA_recombination* DNA_binding "chromosome,_telomeric_region*" G1 None 10 96527 96159 YJL173C S000003709 "ORF,_Verified" "Subunit_of_heterotrimeric_Replication_Protein_A_(RPA),_which_is_a_highly_conserved_single-stranded_DNA_binding_protein_involved_in_DNA_replication,_repair,_and_recombination" YJL176C SWI3 TYE2 chromatin_remodeling general_RNA_polymerase_II_transcription_factor_activity SWI/SNF_complex* None None 10 94528 92051 YJL176C S000003712 "ORF,_Verified" "Subunit_of_the_SWI/SNF_chromatin_remodeling_complex,_which_regulates_transcription_by_remodeling_chromosomes;_required_for_transcription_of_many_genes,_including_ADH1,_ADH2,_GAL1,_HO,_INO1_and_SUC2" YJL177W RPL17B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 10 90784 91655 YJL177W S000003713 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl17Ap_and_has_similarity_to_E._coli_L22_and_rat_L17_ribosomal_proteins" YJL178C ATG27 ETF1 vesicle_organization_and_biogenesis protein_kinase_regulator_activity membrane None None 10 90095 89280 YJL178C S000003714 "ORF,_Verified" Type_I_membrane_protein_involved_in_autophagy_and_the_cytoplasm-to-vacuole_targeting_(Cvt)_pathway;_may_be_involved_in_membrane_delivery_to_the_phagophore_assembly_site YJL179W PFD1 GIM6 protein_folding* unfolded_protein_binding prefoldin_complex None None 10 88785 89114 YJL179W S000003715 "ORF,_Verified" "Subunit_of_heterohexameric_prefoldin,_which_binds_cytosolic_chaperonin_and_transfers_target_proteins_to_it;_involved_in_the_biogenesis_of_actin_and_of_alpha-_and_gamma-tubulin" YJL180C ATP12 None protein_complex_assembly unfolded_protein_binding mitochondrial_matrix None None 10 88558 87581 YJL180C S000003716 "ORF,_Verified" Conserved_protein_required_for_assembly_of_alpha_and_beta_subunits_into_the_F1_sector_of_mitochondrial_F1F0_ATP_synthase;_mutation_of_human_ATP12_reduces_active_ATP_synthase_levels_and_is_associated_with_the_disorder_ATPAF2_deficiency YJL183W MNN11 None protein_amino_acid_glycosylation "alpha-1,6-mannosyltransferase_activity" "alpha-1,6-mannosyltransferase_complex" None None 10 84066 85334 YJL183W S000003719 "ORF,_Verified" "Subunit_of_a_Golgi_mannosyltransferase_complex_that_also_contains_Anp1p,_Mnn9p,_Mnn10p,_and_Hoc1p,_and_mediates_elongation_of_the_polysaccharide_mannan_backbone;_has_homology_to_Mnn10p" YJL184W GON7 PCC2|LDB6 cell_wall_mannoprotein_biosynthesis* molecular_function_unknown cellular_component_unknown None None 10 83446 83817 YJL184W S000003720 "ORF,_Verified" "Protein_proposed_to_be_involved_in_the_modification_of_N-linked_oligosaccharides,_osmotic_stress_response,_telomere_uncapping_and_elongation,_transcription;_component_of_the_EKC/KEOPS_protein_complex_with_Kae1p,_Cgi121p,_Pcc1p,_and_Bud32p" YJL189W RPL39 SPB2|RPL46|PUB2 protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 10 75932 76473 YJL189W S000003725 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_rat_L39_ribosomal_protein;_required_for_ribosome_biogenesis;_exhibits_genetic_interactions_with_SIS1_and_PAB1" YJL190C RPS22A RPS24 protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 10 75301 74909 YJL190C S000003726 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps22Bp_and_has_similarity_to_E._coli_S8_and_rat_S15a_ribosomal_proteins YJL191W RPS14B CRY2 protein_biosynthesis* structural_constituent_of_ribosome* cytosolic_small_ribosomal_subunit_(sensu_Eukaryota)* None None 10 73786 74610 YJL191W S000003727 "ORF,_Verified" "Ribosomal_protein_59_of_the_small_subunit,_required_for_ribosome_assembly_and_20S_pre-rRNA_processing;_mutations_confer_cryptopleurine_resistance;_nearly_identical_to_Rps14Ap_and_similar_to_E._coli_S11_and_rat_S14_ribosomal_proteins" YJL192C SOP4 None ER_to_Golgi_transport molecular_function_unknown endoplasmic_reticulum* None None 10 73413 72709 YJL192C S000003728 "ORF,_Verified" "ER-membrane_protein;_suppressor_of_pma1-7,_deletion_of_SOP4_slows_down_the_export_of_wild-type_Pma1p_and_Pma1-7_from_the_ER" YJL193W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 71365 72573 YJL193W S000003729 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_predicted_to_encode_a_triose_phosphate_transporter_subfamily_member_based_on_phylogenetic_analysis;_similar_to_YOR307C/SLY41;_deletion_mutant_has_a_respiratory_growth_defect" YJL196C ELO1 None "fatty_acid_elongation,_unsaturated_fatty_acid" fatty_acid_elongase_activity membrane M/G1 None 10 68781 67849 YJL196C S000003732 "ORF,_Verified" "Elongase_I,_medium-chain_acyl_elongase,_catalyzes_carboxy-terminal_elongation_of_unsaturated_C12-C16_fatty_acyl-CoAs_to_C16-C18_fatty_acids" YJL198W PHO90 None phosphate_transport phosphate_transporter_activity membrane None None 10 60843 63488 YJL198W S000003734 "ORF,_Verified" "Low-affinity_phosphate_transporter;_deletion_of_pho84,_pho87,_pho89,_pho90,_and_pho91_causes_synthetic_lethality;_transcription_independent_of_Pi_and_Pho4p_activity;_overexpression_results_in_vigorous_growth" YJL200C ACO2 None biological_process_unknown aconitate_hydratase_activity mitochondrion None None 10 58813 56444 YJL200C S000003736 "ORF,_Verified" "Putative_mitochondrial_aconitase_isozyme;_similarity_to_Aco1p,_an_aconitase_required_for_the_TCA_cycle;_expression_induced_during_growth_on_glucose,_by_amino_acid_starvation_via_Gcn4p,_and_repressed_on_ethanol" YJL206C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 49935 47659 YJL206C S000003741 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_similar_to_transcriptional_regulators_from_the_Zn[2]-Cys[6]_binuclear_cluster_protein_family;_mRNA_is_weakly_cell_cycle_regulated,_peaking_in_S_phase;_induced_rapidly_upon_MMS_treatment" YJL207C LAA1 None biological_process_unknown molecular_function_unknown clathrin-coated_vesicle None None 10 47433 41389 YJL207C S000003743 "ORF,_Verified" AP-1_accessory_protein;_colocalizes_with_clathrin_to_the_late-Golgi_apparatus;_involved_in_TGN-endosome_transport;_physically_interacts_with_AP-1;_similar_to_the_mammalian_p200;_may_interact_with_ribosomes;_YJL207C_is_a_non-essential_gene YJL208C NUC1 None DNA_recombination* ribonuclease_activity* mitochondrial_inner_membrane None None 10 41183 40194 YJL208C S000003744 "ORF,_Verified" "Major_mitochondrial_nuclease,_has_RNAse_and_DNA_endo-_and_exonucleolytic_activities;_has_roles_in_mitochondrial_recombination,_apoptosis_and_maintenance_of_polyploidy" YJL210W PEX2 PAS5|CRT1 peroxisome_organization_and_biogenesis protein_binding peroxisomal_membrane None None 10 36919 37734 YJL210W S000003746 "ORF,_Verified" "RING-finger_peroxin,_peroxisomal_membrane_protein_with_a_C-terminal_zinc-binding_RING_domain,_forms_translocation_subcomplex_with_Pex10p_and_Pex12p_which_functions_in_peroxisomal_matrix_protein_import" YJL212C OPT1 GSH11|HGT1 sulfur_metabolism oligopeptide_transporter_activity endoplasmic_reticulum* None None 10 36249 33850 YJL212C S000003748 "ORF,_Verified" Proton-coupled_oligopeptide_transporter_of_the_plasma_membrane;_also_transports_glutathione_and_phytochelatin;_member_of_the_OPT_family YJL216C None None biological_process_unknown "hydrolase_activity,_hydrolyzing_O-glycosyl_compounds" cellular_component_unknown None None 10 26086 24341 YJL216C S000003752 "ORF,_Uncharacterized" "Protein_of_unknown_function,_similar_to_alpha-D-glucosidases;_transcriptionally_activated_by_both_Pdr8p_and_Yrm1p,_along_with_transporters_and_other_genes_involved_in_the_pleiotropic_drug_resistance_(PDR)_phenomenon" YJL217W None None biological_process_unknown molecular_function_unknown cytoplasm G1 None 10 23133 23729 YJL217W S000003753 "ORF,_Uncharacterized" "Cytoplasmic_protein_of_unknown_function;_expression_induced_by_calcium_shortage_and_via_the_copper_sensing_transciption_factor_Mac1p_during_conditons_of_copper_deficiency;_mRNA_is_cell_cycle_regulated,_peaking_in_G1_phase" YJL218W None None biological_process_unknown acetyltransferase_activity cellular_component_unknown None None 10 21973 22563 YJL218W S000003754 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_similar_to_bacterial_galactoside_O-acetyltransferases;_induced_by_oleate_in_an_OAF1/PIP2-dependent_manner;_promoter_contains_an_oleate_response_element_consensus_sequence;_non-essential_gene" YJL222W VTH2 None Golgi_to_vacuole_transport signal_sequence_binding cellular_component_unknown None None 10 11475 16124 YJL222W S000003758 "ORF,_Verified" "Putative_membrane_glycoprotein_with_strong_similarity_to_Vth1p_and_Pep1p/Vps10p,_may_be_involved_in_vacuolar_protein_sorting" YJL223C PAU1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 9138 8776 YJL223C S000003759 "ORF,_Verified" "Part_of_23-member_seripauperin_multigene_family_encoded_mainly_in_subtelomeric_regions,_active_during_alcoholic_fermentation,_regulated_by_anaerobiosis,_negatively_regulated_by_oxygen,_repressed_by_heme" YJL225C None None biological_process_unknown helicase_activity cellular_component_unknown M/G1 None 10 6130 466 YJL225C S000003760 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_similarity_to_DNA_helicases_that_are_also_encoded_within_subtelomeric_Y'_elements_and_induced_in_telomerase_deficient_survivors YJR001W AVT1 None neutral_amino_acid_transport neutral_amino_acid_transporter_activity vacuole S/G2 Up 10 436795 438603 YJR001W S000003761 "ORF,_Verified" "Vacuolar_transporter,_imports_large_neutral_amino_acids_into_the_vacuole;_member_of_a_family_of_seven_S._cerevisiae_genes_(AVT1-7)_related_to_vesicular_GABA-glycine_transporters" YJR002W MPP10 None rRNA_modification* molecular_function_unknown nucleus* None None 10 438857 440638 YJR002W S000003762 "ORF,_Verified" "Component_of_the_SSU_processome_and_90S_preribosome,_required_for_pre-18S_rRNA_processing,_interacts_with_and_controls_the_stability_of_Imp3p_and_Imp4p,_essential_for_viability;_similar_to_human_Mpp10p" YJR003C None None biological_process_unknown molecular_function_unknown mitochondrion G2/M None 10 442545 440986 YJR003C S000003763 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YJR004C SAG1 AG(ALPHA)1 agglutination_during_conjugation_with_cellular_fusion cell_adhesion_molecule_binding cell_wall_(sensu_Fungi) M/G1 None 10 444853 442901 YJR004C S000003764 "ORF,_Verified" "Alpha-agglutinin_of_alpha-cells,_binds_to_Aga1p_during_agglutination,_N-terminal_half_is_homologous_to_the_immunoglobulin_superfamily_and_contains_binding_site_for_a-agglutinin,_C-terminal_half_is_highly_glycosylated_and_contains_GPI_anchor" YJR006W POL31 HYS2|SDP5|HUS2 nucleotide-excision_repair* delta_DNA_polymerase_activity delta_DNA_polymerase_complex G1 None 10 449194 450657 YJR006W S000003766 "ORF,_Verified" "DNA_polymerase_III_(delta)_subunit,_essential_for_cell_viability;_involved_in_DNA_replication_and_DNA_repair" YJR007W SUI2 None translational_initiation translation_initiation_factor_activity cytoplasm* None None 10 451012 451926 YJR007W S000003767 "ORF,_Verified" "Alpha_subunit_of_the_translation_initiation_factor_eIF2,_involved_in_the_identification_of_the_start_codon;_phosphorylation_of_Ser51_is_required_for_regulation_of_translation_by_inhibiting_the_exchange_of_GDP_for_GTP" YJR008W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 10 452422 453438 YJR008W S000003768 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_expression_repressed_by_inosine_and_choline_in_an_Opi1p-dependent_manner;_expression_induced_by_mild_heat-stress_on_a_non-fermentable_carbon_source. YJR009C TDH2 GLD2 glycolysis* glyceraldehyde-3-phosphate_dehydrogenase_(phosphorylating)_activity cytoplasm* None None 10 454673 453675 YJR009C S000003769 "ORF,_Verified" "Glyceraldehyde-3-phosphate_dehydrogenase,_isozyme_2,_involved_in_glycolysis_and_gluconeogenesis;_tetramer_that_catalyzes_the_reaction_of_glyceraldehyde-3-phosphate_to_1,3_bis-phosphoglycerate;_detected_in_the_cytoplasm_and_cell-wall" YJR010C-A SPC1 None signal_peptide_processing molecular_function_unknown signal_peptidase_complex None None 10 458353 458069 YJR010C-A S000003770 "ORF,_Verified" "Subunit_of_the_signal_peptidase_complex_(SPC),_which_cleaves_the_signal_sequence_from_proteins_targeted_to_the_endoplasmic_reticulum_(ER),_homolog_of_the_SPC12_subunit_of_mammalian_signal_peptidase_complex" YJR014W TMA22 RBF22 biological_process_unknown RNA_binding cytoplasm None None 10 461821 462417 YJR014W S000003775 "ORF,_Verified" "Protein_of_unknown_function;_associates_with_ribosomes_and_has_a_putative_RNA_binding_domain;_interacts_with_Tma20p;_similar_to_human_GRAP_and_human_DRP1,_which_interacts_with_human_Tma20p_homolog_MCT-1" YJR015W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 10 462713 464245 YJR015W S000003776 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_localizes_to_the_endoplasmic_reticulum_and_cytoplasm;_predicted_to_encode_a_membrane_transporter_based_on_phylogenetic_analysis;_YJR015W_is_a_non-essential_gene YJR016C ILV3 None branched_chain_family_amino_acid_biosynthesis dihydroxy-acid_dehydratase_activity mitochondrion None None 10 466200 464443 YJR016C S000003777 "ORF,_Verified" "Dihydroxyacid_dehydratase,_catalyzes_third_step_in_the_common_pathway_leading_to_biosynthesis_of_branched-chain_amino_acids" YJR021C REC107 MER2 meiotic_recombination molecular_function_unknown cellular_component_unknown None None 10 469571 468547 YJR021C S000003782 "ORF,_Verified" Protein_involved_in_early_stages_of_meiotic_recombination;_involved_in_coordination_between_the_initiation_of_recombination_and_the_first_division_of_meiosis;_part_of_a_complex_(Rec107p-Mei4p-Rec114p)_required_for_ds_break_formation YJR022W LSM8 None "nuclear_mRNA_splicing,_via_spliceosome*" RNA_binding* nucleus* None None 10 469776 470105 YJR022W S000003783 "ORF,_Verified" "Lsm_(Like_Sm)_protein;_forms_heteroheptameric_complex_(with_Lsm2p,_Lsm3p,_Lsm4p,_Lsm5p,_Lsm6p,_and_Lsm7p)_that_is_part_of_spliceosomal_U6_snRNP_and_is_also_implicated_in_processing_of_pre-tRNA,_pre-snoRNA,_and_pre-rRNA" YJR025C BNA1 HAD1 NAD_biosynthesis "3-hydroxyanthranilate_3,4-dioxygenase_activity" cytoplasm None Up 10 471663 471130 YJR025C S000003786 "ORF,_Verified" "3-hydroxyanthranilic_acid_dioxygenase,_required_for_the_de_novo_biosynthesis_of_NAD_from_tryptophan_via_kynurenine;_expression_regulated_by_Hst1p" YJR026W None None None None None None None 10 472752 474074 YJR026W S000003787 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YJR027W None None None None None None None 10 472752 478020 YJR027W S000003788 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YJR028W None None None None None None None 10 478336 479658 YJR028W S000003789 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YJR029W None None None None None None None 10 478336 483604 YJR029W S000003790 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YJR030C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 10 486188 483951 YJR030C S000003791 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_expression_repressed_in_carbon_limited_vs_carbon_replete_chemostat_cultures;_YJR030C_is_a_non-essential_gene YJR031C GEA1 None ER_to_Golgi_transport* ARF_guanyl-nucleotide_exchange_factor_activity Golgi_vesicle* None None 10 490804 486578 YJR031C S000003792 "ORF,_Verified" "Guanine_nucleotide_exchange_factor_for_ADP_ribosylation_factors_(ARFs),_involved_in_vesicular_transport_between_the_Golgi_and_ER,_Golgi_organization,_and_actin_cytoskeleton_organization;_similar_to_but_not_functionally_redundant_with_Gea2p" YJR032W CPR7 None response_to_stress unfolded_protein_binding* cytosol None None 10 491073 492254 YJR032W S000003793 "ORF,_Verified" "Peptidyl-prolyl_cis-trans_isomerase_(cyclophilin),_catalyzes_the_cis-trans_isomerization_of_peptide_bonds_N-terminal_to_proline_residues;_binds_to_Hsp82p_and_contributes_to_chaperone_activity" YJR034W PET191 None cytochrome_c_oxidase_complex_assembly molecular_function_unknown mitochondrial_inner_membrane None None 10 496675 497001 YJR034W S000003795 "ORF,_Verified" Protein_required_for_assembly_of_cytochrome_c_oxidase;_exists_as_an_oligomer_that_is_integral_to_the_mitochondrial_inner_membrane_and_faces_the_intermembrane_space;_contains_a_twin_Cx9C_motif YJR035W RAD26 None nucleotide-excision_repair* DNA-dependent_ATPase_activity nucleus None None 10 497347 500604 YJR035W S000003796 "ORF,_Verified" Protein_involved_in_transcription-coupled_repair_nucleotide_excision_repair_of_UV-induced_DNA_lesions;_homolog_of_human_CSB_protein YJR039W None None biological_process_unknown molecular_function_unknown mitochondrion None None 10 503928 507293 YJR039W S000003800 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YJR041C URB2 NPA2 ribosome_biogenesis* molecular_function_unknown nucleolus None None 10 513755 510231 YJR041C S000003802 "ORF,_Verified" "Nucleolar_protein_required_for_normal_metabolism_of_the_rRNA_primary_transcript,_proposed_to_be_involved_in_ribosome_biogenesis" YJR044C VPS55 None late_endosome_to_vacuole_transport molecular_function_unknown late_endosome None None 10 519177 518755 YJR044C S000003805 "ORF,_Verified" Late_endosomal_protein_involved_in_late_endosome_to_vacuole_trafficking;_functional_homolog_of_human_obesity_receptor_gene-related_protein_(OB-RGRP) YJR045C SSC1 mtHSP70|ENS1 protein_folding* ATPase_activity* mitochondrion* None None 10 521594 519630 YJR045C S000003806 "ORF,_Verified" "Mitochondrial_matrix_ATPase,_subunit_of_the_presequence_translocase-associated_protein_import_motor_(PAM)_and_of_SceI_endonuclease;_involved_in_protein_folding_and_translocation_into_the_matrix;_phosphorylated;_member_of_HSP70_family" YJR046W TAH11 CDT1|SID2 regulation_of_DNA_replication_initiation molecular_function_unknown cytoplasm* None None 10 522040 523854 YJR046W S000003807 "ORF,_Verified" "DNA_replication_licensing_factor,_required_for_pre-replication_complex_assembly" YJR047C ANB1 TIF51B|HYP1 translational_initiation translation_initiation_factor_activity ribosome None Down 10 525373 524900 YJR047C S000003808 "ORF,_Verified" "Translation_initiation_factor_eIF-5A,_promotes_formation_of_the_first_peptide_bond;_similar_to_and_functionally_redundant_with_Hyp2p;_undergoes_an_essential_hypusination_modification;_expressed_under_anaerobic_conditions" YJR048W CYC1 None electron_transport electron_carrier_activity mitochondrial_intermembrane_space S/G2 Down 10 526327 526656 YJR048W S000003809 "ORF,_Verified" "Cytochrome_c,_isoform_1;_electron_carrier_of_the_mitochondrial_intermembrane_space_that_transfers_electrons_from_ubiquinone-cytochrome_c_oxidoreductase_to_cytochrome_c_oxidase_during_cellular_respiration" YJR053W BFA1 IBD1 conjugation_with_cellular_fusion* GTPase_activator_activity spindle_pole_body None None 10 534019 535743 YJR053W S000003814 "ORF,_Verified" Component_of_the_GTPase-activating_Bfa1p-Bub2p_complex_involved_in_multiple_cell_cycle_checkpoint_pathways_that_control_exit_from_mitosis YJR054W None None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) G1 None 10 536048 537541 YJR054W S000003815 "ORF,_Uncharacterized" Vacuolar_protein_of_unknown_function;_potential_Cdc28p_substrate YJR056C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 10 542494 541784 YJR056C S000003817 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_both_the_cytoplasm_and_the_nucleus YJR058C APS2 YAP17 vesicle-mediated_transport molecular_function_unknown AP-2_adaptor_complex None None 10 545167 544724 YJR058C S000003819 "ORF,_Verified" "Small_subunit_of_the_clathrin-associated_adaptor_complex_AP-2,_which_is_involved_in_protein_sorting_at_the_plasma_membrane;_related_to_the_sigma_subunit_of_the_mammalian_plasma_membrane_clathrin-associated_protein_(AP-2)_complex" YJR059W PTK2 STK2 G1/S_transition_of_mitotic_cell_cycle* protein_kinase_activity cytoplasm* None None 10 545779 548235 YJR059W S000003820 "ORF,_Verified" Putative_serine/threonine_protein_kinase_involved_in_regulation_of_ion_transport_across_plasma_membrane;_enhances_spermine_uptake YJR060W CBF1 CPF1|CEP1 chromatin_assembly_or_disassembly* DNA_binding* nucleus* None None 10 548751 549806 YJR060W S000003821 "ORF,_Verified" "Helix-loop-helix_protein_that_binds_the_motif_CACRTG,_which_is_present_at_several_sites_including_MET_gene_promoters_and_centromere_DNA_element_I_(CDEI);_required_for_nucleosome_positioning_at_this_motif;_targets_Isw1p_to_DNA" YJR061W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 550503 553310 YJR061W S000003822 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_non-essential_gene_with_similarity_to_Mnn4,_a_putative_membrane_protein_involved_in_glycosylation;_transcription_repressed_by_Rm101p" YJR063W RPA12 RRN4 transcription_from_RNA_polymerase_I_promoter DNA-directed_RNA_polymerase_activity DNA-directed_RNA_polymerase_I_complex None Down 10 555187 555564 YJR063W S000003824 "ORF,_Verified" "RNA_polymerase_I_subunit_A12.2;_contains_two_zinc_binding_domains,_and_the_N_terminal_domain_is_responsible_for_anchoring_to_the_RNA_pol_I_complex" YJR064W CCT5 TCP5 protein_folding* unfolded_protein_binding cytoplasm* None None 10 555906 557594 YJR064W S000003825 "ORF,_Verified" "Subunit_of_the_cytosolic_chaperonin_Cct_ring_complex,_related_to_Tcp1p,_required_for_the_assembly_of_actin_and_tubulins_in_vivo" YJR065C ARP3 ACT4 actin_filament_organization* structural_constituent_of_cytoskeleton* Arp2/3_protein_complex None None 10 559150 557801 YJR065C S000003826 "ORF,_Verified" "Essential_component_of_the_Arp2/3_complex,_which_is_a_highly_conserved_actin_nucleation_center_required_for_the_motility_and_integrity_of_actin_patches;_involved_in_endocytosis_and_membrane_growth_and_polarity" YJR066W TOR1 DRR1 meiosis* protein_binding* plasma_membrane* None None 10 559408 566820 YJR066W S000003827 "ORF,_Verified" "PIK-related_protein_kinase_and_rapamycin_target;_subunit_of_TORC1,_a_complex_that_controls_growth_in_response_to_nutrients_by_regulating_translation,_transcription,_ribosome_biogenesis,_nutrient_transport_and_autophagy;_involved_in_meiosis" YJR068W RFC2 None mismatch_repair* DNA_clamp_loader_activity* DNA_replication_factor_C_complex None None 10 567635 568696 YJR068W S000003829 "ORF,_Verified" "Subunit_of_heteropentameric_Replication_factor_C_(RF-C),_which_is_a_DNA_binding_protein_and_ATPase_that_acts_as_a_clamp_loader_of_the_proliferating_cell_nuclear_antigen_(PCNA)_processivity_factor_for_DNA_polymerases_delta_and_epsilon" YJR069C HAM1 None DNA_repair molecular_function_unknown cytoplasm* None None 10 569391 568798 YJR069C S000003830 "ORF,_Verified" "Conserved_protein_with_deoxyribonucleoside_triphosphate_pyrophosphohydrolase_activity,_mediates_exclusion_of_noncanonical_purines_from_deoxyribonucleoside_triphosphate_pools;_mutant_is_sensitive_to_the_base_analog_6-N-hydroxylaminopurine" YJR070C LIA1 MMD1 microtubule_cytoskeleton_organization_and_biogenesis protein_binding cytoplasm* None Down 10 570590 569613 YJR070C S000003831 "ORF,_Verified" "Deoxyhypusine_hydroxylase,_a_HEAT-repeat_containing_metalloenzyme_that_catalyses_hypusine_formation;_binds_to_and_is_required_for_the_modification_of_Hyp2p_(eIF5A);_complements_S._pombe_mmd1_mutants_defective_in_mitochondrial_positioning" YJR072C NPA3 EPA1 aerobic_respiration protein_binding cytoplasm None None 10 572116 570959 YJR072C S000003833 "ORF,_Verified" "Essential,_conserved,_cytoplasmic_ATPase;_phosphorylated_by_the_Pcl1p-Pho85p_kinase_complex" YJR074W MOG1 None protein_import_into_nucleus Ran_GTPase_binding nucleus None None 10 573087 573743 YJR074W S000003835 "ORF,_Verified" "Conserved_nuclear_protein_that_interacts_with_GTP-Gsp1p,_which_is_a_Ran_homolog_of_the_Ras_GTPase_family,_and_stimulates_nucleotide_release,_involved_in_nuclear_protein_import,_nucleotide_release_is_inhibited_by_Yrb1p" YJR075W HOC1 None cell_wall_mannoprotein_biosynthesis* "alpha-1,6-mannosyltransferase_activity*" "alpha-1,6-mannosyltransferase_complex" None None 10 573973 575163 YJR075W S000003836 "ORF,_Verified" "Alpha-1,6-mannosyltransferase_involved_in_cell_wall_mannan_biosynthesis;_subunit_of_a_Golgi-localized_complex_that_also_contains_Anp1p,_Mnn9p,_Mnn11p,_and_Mnn10p;_identified_as_a_suppressor_of_a_cell_lysis_sensitive_pkc1-371_allele" YJR076C CDC11 PSL9 cell_wall_organization_and_biogenesis* structural_constituent_of_cytoskeleton* prospore_membrane* None None 10 576593 575346 YJR076C S000003837 "ORF,_Verified" "Component_of_the_septin_ring_of_the_mother-bud_neck_that_is_required_for_cytokinesis;_septins_recruit_proteins_to_the_neck_and_can_act_as_a_barrier_to_diffusion_at_the_membrane,_and_they_comprise_the_10nm_filaments_seen_with_EM" YJR077C MIR1 None phosphate_transport inorganic_phosphate_transporter_activity mitochondrion* None None 10 578182 577247 YJR077C S000003838 "ORF,_Verified" "Mitochondrial_phosphate_carrier,_imports_inorganic_phosphate_into_mitochondria;_functionally_redundant_with_Pic2p_but_more_abundant_than_Pic2p_under_normal_conditions;_phosphorylated" YJR079W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 580197 581231 YJR079W S000003840 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_mutation_results_in_impaired_mitochondrial_respiration YJR086W STE18 None signal_transduction_during_conjugation_with_cellular_fusion GTPase_activity cytoplasm* None None 10 586060 586392 YJR086W S000003846 "ORF,_Verified" "G_protein_gamma_subunit,_forms_a_dimer_with_Ste4p_to_activate_the_mating_signaling_pathway,_forms_a_heterotrimer_with_Gpa1p_and_Ste4p_to_dampen_signaling;_C-terminus_is_palmitoylated_and_farnesylated,_which_are_required_for_normal_signaling" YJR088C None None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 10 587365 586487 YJR088C S000003848 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_endoplasmic_reticulum YJR090C GRR1 SDC1|SSU2|COT2|CAT80 G1/S_transition_of_mitotic_cell_cycle* protein_binding* cytoplasm* None None 10 594319 590864 YJR090C S000003850 "ORF,_Verified" "F-box_protein_component_of_the_SCF_ubiquitin-ligase_complex;_involved_in_carbon_catabolite_repression,_glucose-dependent_divalent_cation_transport,_high-affinity_glucose_transport,_morphogenesis,_and_sulfite_detoxification" YJR093C FIP1 None mRNA_polyadenylylation* protein_binding* mRNA_cleavage_and_polyadenylation_specificity_factor_complex None None 10 604195 603212 YJR093C S000003853 "ORF,_Verified" "Subunit_of_cleavage_polyadenylation_factor_(CPF),_interacts_directly_with_poly(A)_polymerase_(Pap1p)_to_regulate_its_activity" YJR094C IME1 None meiosis transcription_regulator_activity nucleus None None 10 605643 604561 YJR094C S000003854 "ORF,_Verified" "Master_regulator_of_meiosis_that_is_active_only_during_meiotic_events,_activates_transcription_of_early_meiotic_genes_through_interaction_with_Ume6p,_degraded_by_the_26S_proteasome_following_phosphorylation_by_Ime2p" YJR094W-A RPL43B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 10 608297 608850 YJR094W-A S000003855 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_identical_to_Rpl43Ap_and_has_similarity_to_rat_L37a_ribosomal_protein" YJR098C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 10 615145 613178 YJR098C S000003859 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YJR099W YUH1 None protein_deubiquitination ubiquitin-specific_protease_activity cytoplasm None None 10 615565 616275 YJR099W S000003860 "ORF,_Verified" Ubiquitin_C-terminal_hydrolase_that_cleaves_ubiquitin-protein_fusions_to_generate_monomeric_ubiquitin;_hydrolyzes_the_peptide_bond_at_the_C-terminus_of_ubiquitin;_also_the_major_processing_enzyme_for_the_ubiquitin-like_protein_Rub1p YJR101W RSM26 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 10 618223 619023 YJR101W S000003862 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_small_subunit YJR102C VPS25 VPT25 protein_targeting_to_vacuole* molecular_function_unknown ESCRT_II_complex None Up 10 619754 619146 YJR102C S000003863 "ORF,_Verified" "Component_of_the_ESCRT-II_complex,_which_is_involved_in_ubiquitin-dependent_sorting_of_proteins_into_the_endosome" YJR103W URA8 None phospholipid_biosynthesis* CTP_synthase_activity cytosol None None 10 620743 622437 YJR103W S000003864 "ORF,_Verified" "Minor_CTP_synthase_isozyme_(see_also_URA7),_catalyzes_the_ATP-dependent_transfer_of_the_amide_nitrogen_from_glutamine_to_UTP,_forming_CTP,_the_final_step_in_de_novo_biosynthesis_of_pyrimidines;_involved_in_phospholipid_biosynthesis" YJR104C SOD1 CRS4 zinc_ion_homeostasis* "copper,_zinc_superoxide_dismutase_activity" cytosol* None None 10 623002 622538 YJR104C S000003865 "ORF,_Verified" Cytosolic_superoxide_dismutase;_some_mutations_are_analogous_to_those_that_cause_ALS_(amyotrophic_lateral_sclerosis)_in_humans YJR106W ECM27 None cell_wall_organization_and_biogenesis molecular_function_unknown cellular_component_unknown None None 10 624826 627003 YJR106W S000003867 "ORF,_Verified" Non-essential_protein_of_unknown_function YJR107W None None biological_process_unknown lipase_activity cellular_component_unknown None None 10 627329 628315 YJR107W S000003868 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_has_sequence_or_structural_similarity_to_lipases YJR108W ABM1 None microtubule_cytoskeleton_organization_and_biogenesis molecular_function_unknown cellular_component_unknown None None 10 628702 629073 YJR108W S000003869 "ORF,_Verified" "Protein_of_unknown_function,_required_for_normal_microtubule_organization" YJR109C CPA2 None arginine_biosynthesis carbamoyl-phosphate_synthase_(glutamine-hydrolyzing)_activity carbamoyl-phosphate_synthase_complex None Up 10 632931 629575 YJR109C S000003870 "ORF,_Verified" "Large_subunit_of_carbamoyl_phosphate_synthetase,_which_catalyzes_a_step_in_the_synthesis_of_citrulline,_an_arginine_precursor" YJR111C None None biological_process_unknown molecular_function_unknown mitochondrion None Up 10 636696 635845 YJR111C S000003872 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_mitochondria YJR112W NNF1 None chromosome_segregation molecular_function_unknown kinetochore* None None 10 637020 637625 YJR112W S000003873 "ORF,_Verified" Essential_component_of_the_MIND_kinetochore_complex_(Mtw1p_Including_Nnf1p-Nsl1p-Dsn1p)_which_joins_kinetochore_subunits_contacting_DNA_to_those_contacting_microtubules;_required_for_accurate_chromosome_segregation YJR113C RSM7 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 10 638965 638222 YJR113C S000003874 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_small_subunit,_has_similarity_to_E._coli_S7_ribosomal_protein" YJR115W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 639932 640441 YJR115W S000003876 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YJR116W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 640815 641654 YJR116W S000003877 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YJR117W STE24 PIO2|AFC1 peptide_pheromone_maturation metalloendopeptidase_activity* integral_to_endoplasmic_reticulum_membrane None None 10 641997 643358 YJR117W S000003878 "ORF,_Verified" "Highly_conserved_zinc_metalloprotease_that_functions_in_two_steps_of_a-factor_maturation,_C-terminal_CAAX_proteolysis_and_the_first_step_of_N-terminal_proteolytic_processing;_contains_multiple_transmembrane_spans" YJR118C ILM1 None mitochondrial_genome_maintenance* molecular_function_unknown endoplasmic_reticulum None None 10 644091 643480 YJR118C S000003879 "ORF,_Verified" Protein_of_unknown_function;_may_be_involved_in_mitochondrial_DNA_maintenance;_required_for_slowed_DNA_synthesis-induced_filamentous_growth YJR119C JHD2 KDM5 biological_process_unknown molecular_function_unknown cytoplasm* None None 10 646480 644294 YJR119C S000003880 "ORF,_Verified" JmjC_domain_family_histone_demethylase_specific_for_H3-K4_(lysine_at_position_4_of_the_histone_H3_protein);_removes_methyl_groups_specifically_added_by_Set1p_methyltransferase YJR122W IBA57 CAF17 biological_process_unknown molecular_function_unknown mitochondrion None None 10 649766 651259 YJR122W S000003883 "ORF,_Verified" Mitochondrial_matrix_protein_involved_in_the_incorporation_of_iron-sulfur_clusters_into_mitochondrial_aconitase-type_proteins;_activates_the_radical-SAM_family_members_Bio2p_and_Lip5p;_interacts_with_Ccr4p_in_the_two-hybrid_system YJR123W RPS5 None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 10 651891 652568 YJR123W S000003884 "ORF,_Verified" "Protein_component_of_the_small_(40S)_ribosomal_subunit,_the_least_basic_of_the_non-acidic_ribosomal_proteins;_phosphorylated_in_vivo;_essential_for_viability;_has_similarity_to_E._coli_S7_and_rat_S5_ribosomal_proteins" YJR124C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 10 654228 652882 YJR124C S000003885 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_expression_induced_under_calcium_shortage YJR125C ENT3 None endocytosis* protein_binding actin_cortical_patch* None Up 10 655953 654727 YJR125C S000003886 "ORF,_Verified" Protein_containing_an_N-terminal_epsin-like_domain_involved_in_clathrin_recruitment_and_traffic_between_the_Golgi_and_endosomes;_associates_with_the_clathrin_adaptor_Gga2p YJR127C RSF2 ZMS1 regulation_of_transcription transcription_factor_activity nucleus None None 10 663049 658907 YJR127C S000003888 "ORF,_Verified" "Zinc-finger_protein_involved_in_transcriptional_control_of_both_nuclear_and_mitochondrial_genes,_many_of_which_specify_products_required_for_glycerol-based_growth,_respiration,_and_other_functions" YJR129C None None biological_process_unknown S-adenosylmethionine-dependent_methyltransferase_activity cytoplasm None None 10 665009 663990 YJR129C S000003890 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_predicted_S-adenosylmethionine-dependent_methyltransferase_of_the_seven_beta-strand_family;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YJR130C STR2 None sulfur_metabolism cystathionine_gamma-synthase_activity cytoplasm* None Up 10 667127 665208 YJR130C S000003891 "ORF,_Verified" "Cystathionine_gamma-synthase,_converts_cysteine_into_cystathionine" YJR131W MNS1 None protein_amino_acid_N-linked_glycosylation* "mannosyl-oligosaccharide_1,2-alpha-mannosidase_activity" endoplasmic_reticulum None None 10 667634 669283 YJR131W S000003892 "ORF,_Verified" "Alpha-1,2-mannosidase_involved_in_ER_quality_control;_catalyzes_the_removal_of_one_mannose_residue_from_Man9GlcNAc_to_produce_a_single_isomer_of_Man8GlcNAc_in_N-linked_oligosaccharide_biosynthesis;_integral_to_ER_membrane" YJR132W NMD5 KAP119 protein_import_into_nucleus protein_carrier_activity cytoplasm* None None 10 669512 672658 YJR132W S000003893 "ORF,_Verified" "Karyopherin,_a_carrier_protein_involved_in_nuclear_import_of_proteins;_importin_beta_homolog" YJR133W XPT1 None purine_nucleotide_biosynthesis xanthine_phosphoribosyltransferase_activity cytoplasm None None 10 672981 673610 YJR133W S000003894 "ORF,_Verified" "Xanthine-guanine_phosphoribosyl_transferase,_required_for_xanthine_utilization_and_for_optimal_utilization_of_guanine" YJR134C SGM1 None biological_process_unknown molecular_function_unknown Golgi_apparatus* None None 10 675842 673719 YJR134C S000003895 "ORF,_Verified" "Protein_of_unknown_function,_required_for_wild-type_growth_rate_on_galactose_and_mannose;_localizes_to_COPI_coated_vesicles_and_the_Golgi_apparatus" YJR135C MCM22 None chromosome_segregation protein_binding condensed_nuclear_chromosome_kinetochore None None 10 676768 676049 YJR135C S000003896 "ORF,_Verified" Protein_involved_in_minichromosome_maintenance;_component_of_the_kinetochore;_binds_to_centromeric_DNA_in_a_Ctf19p-dependent_manner YJR135W-A TIM8 None protein_import_into_mitochondrial_inner_membrane protein_transporter_activity mitochondrial_intermembrane_space_protein_transporter_complex None None 10 676961 677224 YJR135W-A S000007348 "ORF,_Verified" Mitochondrial_intermembrane_space_protein_mediating_import_and_insertion_of_polytopic_inner_membrane_proteins;_homolog_of_human_DDP1_(deafness_dystonia_peptide_1)_which_is_mutated_in_the_X-linked_Mohr-Tranebjaerg_syndrome YJR136C None None protein_biosynthesis molecular_function_unknown cytoplasm None None 10 678696 677431 YJR136C S000003897 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_may_interact_with_mitochondrial_ribosomal_protein_Rsm23p;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YJR137C ECM17 MET5 cell_wall_organization_and_biogenesis* sulfite_reductase_(NADPH)_activity cytoplasm* S None 10 683275 678947 YJR137C S000003898 "ORF,_Verified" "Sulfite_reductase_beta_subunit,_involved_in_amino_acid_biosynthesis,_transcription_repressed_by_methionine" YJR138W IML1 None biological_process_unknown molecular_function_unknown vacuolar_membrane_(sensu_Fungi) None None 10 684557 689311 YJR138W S000003899 "ORF,_Verified" "Protein_of_unknown_function,_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuolar_membrane" YJR139C HOM6 None methionine_metabolism* homoserine_dehydrogenase_activity cytoplasm* None None 10 690514 689435 YJR139C S000003900 "ORF,_Verified" "Homoserine_dehydrogenase_(L-homoserine:NADP_oxidoreductase),_dimeric_enzyme_that_catalyzes_the_third_step_in_the_common_pathway_for_methionine_and_threonine_biosynthesis;_enzyme_has_nucleotide-binding,_dimerization_and_catalytic_regions" YJR140C HIR3 HPC1 G1/S-specific_transcription_in_mitotic_cell_cycle transcription_corepressor_activity nucleus None None 10 695686 690740 YJR140C S000003901 "ORF,_Verified" "Subunit_of_the_HIR_complex,_a_nucleosome_assembly_complex_involved_in_regulation_of_histone_gene_transcription;_involved_in_position-dependent_gene_silencing_and_nucleosome_reassembly" YJR141W None None mRNA_processing molecular_function_unknown cellular_component_unknown None None 10 695896 696939 YJR141W S000003902 "ORF,_Uncharacterized" Essential_protein_of_unknown_function YJR143C PMT4 None protein_amino_acid_O-linked_glycosylation dolichyl-phosphate-mannose-protein_mannosyltransferase_activity endoplasmic_reticulum None None 10 700604 698316 YJR143C S000003904 "ORF,_Verified" "Protein_O-mannosyltransferase,_transfers_mannose_residues_from_dolichyl_phosphate-D-mannose_to_protein_serine/threonine_residues;_appears_to_form_homodimers_in_vivo_and_does_not_complex_with_other_Pmt_proteins;_target_for_new_antifungals" YJR144W MGM101 MGM9 DNA_repair* DNA_binding mitochondrial_nucleoid* None None 10 700872 701681 YJR144W S000003905 "ORF,_Verified" "Protein_involved_in_mitochondrial_genome_maintenance;_component_of_the_mitochondrial_nucleoid,_required_for_the_repair_of_oxidative_mtDNA_damage" YJR145C RPS4A None protein_biosynthesis* structural_constituent_of_ribosome cytoplasm* None None 10 703058 702017 YJR145C S000003906 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_mutation_affects_20S_pre-rRNA_processing;_identical_to_Rps4Bp_and_has_similarity_to_rat_S4_ribosomal_protein YJR147W HMS2 None pseudohyphal_growth molecular_function_unknown cytoplasm* None None 10 704186 705262 YJR147W S000003908 "ORF,_Verified" Protein_with_similarity_to_heat_shock_transcription_factors;_overexpression_suppresses_the_pseudohyphal_filamentation_defect_of_a_diploid_mep1_mep2_homozygous_null_mutant YJR148W BAT2 ECA40|TWT2 branched_chain_family_amino_acid_biosynthesis* branched-chain-amino-acid_transaminase_activity cytoplasm* G1 None 10 705734 706864 YJR148W S000003909 "ORF,_Verified" "Cytosolic_branched-chain_amino_acid_aminotransferase,_homolog_of_murine_ECA39;_highly_expressed_during_stationary_phase_and_repressed_during_logarithmic_phase" YJR149W None None biological_process_unknown molecular_function_unknown cytoplasm None None 10 707150 708364 YJR149W S000003910 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YJR150C DAN1 CCW13 sterol_transport molecular_function_unknown cell_wall_(sensu_Fungi) None None 10 709697 708801 YJR150C S000003911 "ORF,_Verified" "Cell_wall_mannoprotein_with_similarity_to_Tir1p,_Tir2p,_Tir3p,_and_Tir4p;_expressed_under_anaerobic_conditions,_completely_repressed_during_aerobic_growth" YJR151C DAN4 None biological_process_unknown molecular_function_unknown cell_wall_(sensu_Fungi) None None 10 715730 712245 YJR151C S000003912 "ORF,_Verified" "Cell_wall_mannoprotein_with_similarity_to_Tir1p,_Tir2p,_Tir3p,_and_Tir4p;_expressed_under_anaerobic_conditions,_completely_repressed_during_aerobic_growth" YJR152W DAL5 UREP1 allantoate_transport allantoate_transporter_activity plasma_membrane None None 10 719656 721287 YJR152W S000003913 "ORF,_Verified" Allantoin_permease;_ureidosuccinate_permease;_expression_is_constitutive_but_sensitive_to_nitrogen_catabolite_repression YJR154W None None biological_process_unknown molecular_function_unknown cytoplasm G1 None 10 725774 726814 YJR154W S000003915 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YJR155W AAD10 None aldehyde_metabolism aryl-alcohol_dehydrogenase_activity cellular_component_unknown G1 None 10 727395 728261 YJR155W S000003916 "ORF,_Verified" Putative_aryl-alcohol_dehydrogenase_with_similarity_to_P._chrysosporium_aryl-alcohol_dehydrogenase;_mutational_analysis_has_not_yet_revealed_a_physiological_role YJR156C THI11 None thiamin_biosynthesis protein_binding cellular_component_unknown None None 10 729586 728564 YJR156C S000003917 "ORF,_Verified" "Protein_involved_in_synthesis_of_the_thiamine_precursor_hydroxymethylpyrimidine_(HMP);_member_of_a_subtelomeric_gene_family_including_THI5,_THI11,_THI12,_and_THI13" YJR158W HXT16 None hexose_transport glucose_transporter_activity* plasma_membrane None None 10 732430 734133 YJR158W S000003919 "ORF,_Verified" "Protein_of_unknown_function_with_similarity_to_hexose_transporter_family_members,_expression_is_repressed_by_high_levels_of_glucose" YJR159W SOR1 SDH1 fructose_metabolism* L-iditol_2-dehydrogenase_activity cellular_component_unknown None None 10 736034 737107 YJR159W S000003920 "ORF,_Verified" Sorbitol_dehydrogenase;_expression_is_induced_in_the_presence_of_sorbitol_or_xylose YJR160C MPH3 None carbohydrate_transport carbohydrate_transporter_activity* plasma_membrane None None 10 739806 737998 YJR160C S000003921 "ORF,_Verified" "Alpha-glucoside_permease,_transports_maltose,_maltotriose,_alpha-methylglucoside,_and_turanose;_identical_to_Mph2p;_encoded_in_a_subtelomeric_position_in_a_region_likely_to_have_undergone_duplication" YKL001C MET14 None methionine_metabolism* adenylylsulfate_kinase_activity cytoplasm* S None 11 439028 438420 YKL001C S000001484 "ORF,_Verified" "Adenylylsulfate_kinase,_required_for_sulfate_assimilation_and_involved_in_methionine_metabolism" YKL002W DID4 CHM2|VPS2|VPT14|VPL2|REN1|GRD7 protein_retention_in_Golgi* protein_binding cytoplasm* None None 11 437421 438187 YKL002W S000001485 "ORF,_Verified" "Class_E_Vps_protein_of_the_ESCRT-III_complex,_required_for_sorting_of_integral_membrane_proteins_into_lumenal_vesicles_of_multivesicular_bodies,_and_for_delivery_of_newly_synthesized_vacuolar_enzymes_to_the_vacuole,_involved_in_endocytosis" YKL003C MRP17 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_small_ribosomal_subunit None None 11 437135 436740 YKL003C S000001486 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_small_subunit;_MRP17_exhibits_genetic_interactions_with_PET122,_encoding_a_COX3-specific_translational_activator" YKL004W AUR1 None sphingolipid_metabolism inositol_phosphoceramide_synthase_activity Golgi_apparatus S/G2 None 11 435223 436428 YKL004W S000001487 "ORF,_Verified" "Phosphatidylinositol:ceramide_phosphoinositol_transferase_(IPC_synthase),_required_for_sphingolipid_synthesis;_can_mutate_to_confer_aureobasidin_A_resistance" YKL006C-A SFT1 None intra-Golgi_transport v-SNARE_activity Golgi_membrane None None 11 430275 429841 YKL006C-A S000002101 "ORF,_Verified" "Intra-Golgi_v-SNARE,_required_for_transport_of_proteins_between_an_early_and_a_later_Golgi_compartment" YKL006W RPL14A None protein_biosynthesis structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 11 431549 432363 YKL006W S000001489 "ORF,_Verified" "N-terminally_acetylated_protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl14Bp_and_has_similarity_to_rat_L14_ribosomal_protein;_rpl14a_csh5_double_null_mutant_exhibits_synthetic_slow_growth" YKL007W CAP1 None barbed-end_actin_filament_capping actin_filament_binding actin_cortical_patch* None Up 11 428945 429751 YKL007W S000001490 "ORF,_Verified" Alpha_subunit_of_the_capping_protein_(CP)_heterodimer_(Cap1p_and_Cap2p)_which_binds_to_the_barbed_ends_of_actin_filaments_preventing_further_polymerization;_localized_predominantly_to_cortical_actin_patches YKL008C LAC1 DGT1 ceramide_biosynthesis* sphingosine_N-acyltransferase_activity endoplasmic_reticulum S None 11 428194 426938 YKL008C S000001491 "ORF,_Verified" "Ceramide_synthase_component,_involved_in_synthesis_of_ceramide_from_C26(acyl)-coenzyme_A_and_dihydrosphingosine_or_phytosphingosine,_functionally_equivalent_to_Lag1p" YKL009W MRT4 None rRNA_processing* molecular_function_unknown nucleus* None Down 11 425885 426595 YKL009W S000001492 "ORF,_Verified" "Protein_involved_in_mRNA_turnover_and_ribosome_assembly,_localizes_to_the_nucleolus" YKL010C UFD4 None protein_monoubiquitination* ubiquitin-protein_ligase_activity cytoplasm* None None 11 425518 421067 YKL010C S000001493 "ORF,_Verified" "Ubiquitin-protein_ligase_(E3)_that_interacts_with_Rpt4p_and_Rpt6p,_two_subunits_of_the_19S_particle_of_the_26S_proteasome;_cytoplasmic_E3_involved_in_the_degradation_of_ubiquitin_fusion_proteins" YKL011C CCE1 MGT1 DNA_recombination endodeoxyribonuclease_activity mitochondrial_inner_membrane None None 11 420859 419798 YKL011C S000001494 "ORF,_Verified" "Mitochondrial_cruciform_cutting_endonuclease,_cleaves_Holliday_junctions_formed_during_recombination_of_mitochondrial_DNA" YKL012W PRP40 None "nuclear_mRNA_splicing,_via_spliceosome" RNA_binding snRNP_U1 None None 11 417953 419704 YKL012W S000001495 "ORF,_Verified" "U1_snRNP_protein_involved_in_splicing,_interacts_with_the_branchpoint-binding_protein_during_the_formation_of_the_second_commitment_complex" YKL013C ARC19 None mitochondrion_inheritance* structural_molecule_activity Arp2/3_protein_complex None None 11 417666 417151 YKL013C S000001496 "ORF,_Verified" "Subunit_of_the_ARP2/3_complex,_which_is_required_for_the_motility_and_integrity_of_cortical_actin_patches" YKL015W PUT3 None positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* specific_RNA_polymerase_II_transcription_factor_activity* nucleus None None 11 408187 411126 YKL015W S000001498 "ORF,_Verified" "Transcriptional_activator_of_proline_utilization_genes,_constitutively_binds_PUT1_and_PUT2_promoter_sequences_and_undergoes_a_conformational_change_to_form_the_active_state;_has_a_Zn(2)-Cys(6)_binuclear_cluster_domain" YKL016C ATP7 None protein_complex_assembly* structural_molecule_activity* "proton-transporting_ATP_synthase,_stator_stalk_(sensu_Eukaryota)" None None 11 407632 407108 YKL016C S000001499 "ORF,_Verified" "Subunit_d_of_the_stator_stalk_of_mitochondrial_F1F0_ATP_synthase,_which_is_a_large,_evolutionarily_conserved_enzyme_complex_required_for_ATP_synthesis" YKL017C HCS1 DIP1 lagging_strand_elongation DNA_helicase_activity alpha_DNA_polymerase:primase_complex None None 11 406884 404833 YKL017C S000001500 "ORF,_Verified" Hexameric_DNA_polymerase_alpha-associated_DNA_helicase_A_involved_in_lagging_strand_DNA_synthesis;_contains_single-stranded_DNA_stimulated_ATPase_and_dATPase_activities;_replication_protein_A_stimulates_helicase_and_ATPase_activities YKL018W SWD2 SAF37|CPS35 telomere_maintenance* histone_lysine_N-methyltransferase_activity_(H3-K4_specific) mRNA_cleavage_and_polyadenylation_specificity_factor_complex* None None 11 403745 404734 YKL018W S000001501 "ORF,_Verified" "Subunit_of_the_COMPASS_(Set1C)_complex,_which_methylates_histone_H3_on_lys_4_and_is_involved_in_telomeric_silencing;_subunit_of_CPF_(cleavage_and_polyadenylation_factor),_a_complex_involved_in_RNAP_II_transcription_termination" YKL019W RAM2 None peptide_pheromone_maturation* protein_farnesyltransferase_activity* CAAX-protein_geranylgeranyltransferase_complex* None None 11 402211 403161 YKL019W S000001502 "ORF,_Verified" Alpha_subunit_of_both_the_farnesyltransferase_and_type_I_geranylgeranyltransferase_that_catalyze_prenylation_of_proteins_containing_a_CAAX_consensus_motif;_essential_protein_required_for_membrane_localization_of_Ras_proteins_and_a-factor YKL020C SPT23 None positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus* None None 11 401723 398475 YKL020C S000001503 "ORF,_Verified" "ER_membrane_protein_involved_in_regulation_of_OLE1_transcription,_acts_with_homolog_Mga2p;_inactive_ER_form_dimerizes_and_one_subunit_is_then_activated_by_ubiquitin/proteasome-dependent_processing_followed_by_nuclear_targeting" YKL021C MAK11 None ribosomal_large_subunit_biogenesis molecular_function_unknown membrane_fraction None None 11 398393 396987 YKL021C S000001504 "ORF,_Verified" "Protein_involved_in_an_early,_nucleolar_step_of_60S_ribosomal_subunit_biogenesis;_essential_for_cell_growth_and_replication_of_killer_M1_dsRNA_virus;_contains_four_beta-transducin_repeats" YKL022C CDC16 None mitotic_sister_chromatid_segregation* protein_binding* anaphase-promoting_complex None None 11 396891 394369 YKL022C S000001505 "ORF,_Verified" "Subunit_of_the_anaphase-promoting_complex/cyclosome_(APC/C),_which_is_a_ubiquitin-protein_ligase_required_for_degradation_of_anaphase_inhibitors,_including_mitotic_cyclins,_during_the_metaphase/anaphase_transition;_required_for_sporulation" YKL023W None None biological_process_unknown molecular_function_unknown cytoplasm None None 11 393364 394197 YKL023W S000001506 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_predicted_by_computational_methods_to_be_involved_in_mRNA_degradation;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm" YKL024C URA6 SOC8 de_novo'_pyrimidine_base_biosynthesis* uridine_kinase_activity cytoplasm* None None 11 392783 392169 YKL024C S000001507 "ORF,_Verified" "Uridylate_kinase,_catalyzes_the_seventh_enzymatic_step_in_the_de_novo_biosynthesis_of_pyrimidines,_converting_uridine_monophosphate_(UMP)_into_uridine-5'-diphosphate_(UDP)" YKL025C PAN3 ECM35 DNA_repair* poly(A)-specific_ribonuclease_activity cytoplasm* None None 11 391922 389883 YKL025C S000001508 "ORF,_Verified" "Essential_subunit_of_the_Pan2p-Pan3p_poly(A)-ribonuclease_complex,_which_acts_to_control_poly(A)_tail_length_and_regulate_the_stoichiometry_and_activity_of_postreplication_repair_complexes" YKL026C GPX1 None response_to_oxidative_stress glutathione_peroxidase_activity cellular_component_unknown None None 11 389526 389023 YKL026C S000001509 "ORF,_Verified" Phospholipid_hydroperoxide_glutathione_peroxidase_induced_by_glucose_starvation_that_protects_cells_from_phospholipid_hydroperoxides_and_nonphospholipid_peroxides_during_oxidative_stress YKL028W TFA1 None transcription_initiation_from_RNA_polymerase_II_promoter general_RNA_polymerase_II_transcription_factor_activity transcription_factor_TFIIE_complex None None 11 385401 386849 YKL028W S000001511 "ORF,_Verified" "TFIIE_large_subunit,_involved_in_recruitment_of_RNA_polymerase_II_to_the_promoter,_activation_of_TFIIH,_and_promoter_opening" YKL032C IXR1 ORD1 DNA_repair DNA_binding nuclear_chromosome None None 11 381501 379708 YKL032C S000001515 "ORF,_Verified" "Protein_that_binds_DNA_containing_intrastrand_cross-links_formed_by_cisplatin,_contains_two_HMG_(high_mobility_group_box)_domains,_which_confer_the_ability_to_bend_cisplatin-modified_DNA;_mediates_aerobic_transcriptional_repression_of_COX5b" YKL033W-A None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 374148 374858 YKL033W-A S000007242 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_similar_to_uncharacterized_proteins_from_other_fungi YKL034W TUL1 None protein_ubiquitination* ubiquitin-protein_ligase_activity Golgi_apparatus None Up 11 371472 373748 YKL034W S000001517 "ORF,_Verified" "Golgi-localized_RING-finger_ubiquitin_ligase_(E3),_involved_in_ubiquitinating_and_sorting_membrane_proteins_that_contain_polar_transmembrane_domains_to_multivesicular_bodies_for_delivery_to_the_vacuole_for_quality_control_purposes" YKL035W UGP1 None protein_amino_acid_glycosylation* UTP:glucose-1-phosphate_uridylyltransferase_activity cytoplasm S/G2 None 11 369534 371033 YKL035W S000001518 "ORF,_Verified" "UDP-glucose_pyrophosphorylase_(UGPase),_catalyses_the_reversible_formation_of_UDP-Glc_from_glucose_1-phosphate_and_UTP,_involved_in_a_wide_variety_of_metabolic_pathways,_expression_modulated_by_Pho85p_through_Pho4p" YKL037W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 369008 369364 YKL037W S000001520 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_null_mutant_is_viable_and_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation) YKL038W RGT1 None glucose_metabolism* DNA_binding* nucleus None None 11 365248 368760 YKL038W S000001521 "ORF,_Verified" Glucose-responsive_transcription_factor_that_regulates_expression_of_several_glucose_transporter_(HXT)_genes_in_response_to_glucose;_binds_to_promoters_and_acts_both_as_a_transcriptional_activator_and_repressor YKL039W PTM1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 362265 363836 YKL039W S000001522 "ORF,_Verified" "Protein_of_unknown_function,_copurifies_with_late_Golgi_vesicles_containing_the_v-SNARE_Tlg2p" YKL040C NFU1 NUB1 iron_ion_homeostasis molecular_function_unknown mitochondrial_matrix None None 11 361471 360701 YKL040C S000001523 "ORF,_Verified" "Protein_involved_in_iron_metabolism_in_mitochondria;_similar_to_NifU,_which_is_a_protein_required_for_the_maturation_of_the_Fe/S_clusters_of_nitrogenase_in_nitrogen-fixing_bacteria" YKL041W VPS24 DID3 late_endosome_to_vacuole_transport* molecular_function_unknown cytoplasm* None None 11 359786 360460 YKL041W S000001524 "ORF,_Verified" One_of_four_subunits_of_the_endosomal_sorting_complex_required_for_transport_III_(ESCRT-III);_forms_an_ESCRT-III_subcomplex_with_Did4p;_involved_in_the_sorting_of_transmembrane_proteins_into_the_multivesicular_body_(MVB)_pathway YKL042W SPC42 None microtubule_nucleation* structural_constituent_of_cytoskeleton central_plaque_of_spindle_pole_body* G1 None 11 358119 359210 YKL042W S000001525 "ORF,_Verified" "Central_plaque_component_of_spindle_pole_body_(SPB);_involved_in_SPB_duplication,_may_facilitate_attachment_of_the_SPB_to_the_nuclear_membrane" YKL043W PHD1 None pseudohyphal_growth specific_RNA_polymerase_II_transcription_factor_activity nucleus G2/M None 11 356392 357492 YKL043W S000001526 "ORF,_Verified" "Transcriptional_activator_that_enhances_pseudohyphal_growth;_regulates_expression_of_FLO11,_an_adhesin_required_for_pseudohyphal_filament_formation;_similar_to_StuA,_an_A._nidulans_developmental_regulator;_potential_Cdc28p_substrate" YKL045W PRI2 None DNA_replication_initiation* alpha_DNA_polymerase_activity nucleus* G1 None 11 353137 354723 YKL045W S000001528 "ORF,_Verified" "Subunit_of_DNA_primase,_which_is_required_for_DNA_synthesis_and_double-strand_break_repair" YKL046C DCW1 None budding_cell_bud_growth* mannosidase_activity membrane_fraction* None None 11 352268 350919 YKL046C S000001529 "ORF,_Verified" "Putative_mannosidase,_GPI-anchored_membrane_protein_required_for_cell_wall_biosynthesis_in_bud_formation;homologous_to_Dfg5p" YKL047W None None biological_process_unknown molecular_function_unknown cytoplasm None None 11 349107 350657 YKL047W S000001530 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YKL048C ELM1 LDB9 protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity contractile_ring_(sensu_Saccharomyces) S/G2 None 11 348780 346858 YKL048C S000001531 "ORF,_Verified" "Serine/threonine_protein_kinase_that_regulates_cellular_morphogenesis,_septin_behavior,_and_cytokinesis;_required_for_the_regulation_of_other_kinases;_forms_part_of_the_bud_neck_ring" YKL049C CSE4 CSL2 mitotic_sister_chromatid_segregation centromeric_DNA_binding kinetochore* None None 11 346408 345719 YKL049C S000001532 "ORF,_Verified" "Centromere_protein_that_resembles_histones,_required_for_proper_kinetochore_function;_homolog_of_human_CENP-A" YKL050C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 345264 342496 YKL050C S000001533 "ORF,_Verified" Protein_of_unknown_function;_the_YKL050W_protein_is_a_target_of_the_SCFCdc4_ubiquitin_ligase_complex_and_YKL050W_transcription_is_regulated_by_Azf1p YKL051W SFK1 None actin_cytoskeleton_organization_and_biogenesis* molecular_function_unknown plasma_membrane None None 11 340956 342017 YKL051W S000001534 "ORF,_Verified" "Plasma_membrane_protein_that_may_act_together_with_or_upstream_of_Stt4p_to_generate_normal_levels_of_the_essential_phospholipid_PI4P,_at_least_partially_mediates_proper_localization_of_Stt4p_to_the_plasma_membrane" YKL052C ASK1 None mitotic_spindle_organization_and_biogenesis_in_nucleus* structural_constituent_of_cytoskeleton condensed_nuclear_chromosome_kinetochore* S/G2 None 11 340190 339312 YKL052C S000001535 "ORF,_Verified" "Essential_subunit_of_the_Dam1_complex_(aka_DASH_complex),_couples_kinetochores_to_the_force_produced_by_MT_depolymerization_thereby_aiding_in_chromosome_segregation;_phosphorylated_during_the_cell_cycle_by_cyclin-dependent_kinases" YKL053C-A MDM35 None mitochondrion_organization_and_biogenesis molecular_function_unknown cytoplasm* None None 11 339086 338826 YKL053C-A S000007243 "ORF,_Verified" Mitochondrial_intermembrane_space_cysteine_motif_protein;_mutation_affects_mitochondrial_distribution_and_morphology YKL055C OAR1 None aerobic_respiration* 3-oxoacyl-[acyl-carrier_protein]_reductase_activity mitochondrion None None 11 335801 334965 YKL055C S000001538 "ORF,_Verified" "Mitochondrial_3-oxoacyl-[acyl-carrier-protein]_reductase,_may_comprise_a_type_II_mitochondrial_fatty_acid_synthase_along_with_Mct1p" YKL058W TOA2 None transcription_initiation_from_RNA_polymerase_II_promoter general_RNA_polymerase_II_transcription_factor_activity transcription_factor_TFIIA_complex None None 11 329810 330178 YKL058W S000001541 "ORF,_Verified" "TFIIA_small_subunit;_involved_in_transcriptional_activation,_acts_as_antirepressor_or_as_coactivator;_homologous_to_smallest_subunit_of_human_and_Drosophila_TFIIA" YKL059C MPE1 None mRNA_polyadenylylation* RNA_binding mRNA_cleavage_and_polyadenylation_specificity_factor_complex None None 11 329087 327762 YKL059C S000001542 "ORF,_Verified" "Essential_conserved_subunit_of_CPF_(cleavage_and_polyadenylation_factor),_plays_a_role_in_3'_end_formation_of_mRNA_via_the_specific_cleavage_and_polyadenylation_of_pre-mRNA,_contains_a_putative_RNA-binding_zinc_knuckle_motif" YKL060C FBA1 LOT1 glycolysis* fructose-bisphosphate_aldolase_activity cytoplasm None None 11 327131 326052 YKL060C S000001543 "ORF,_Verified" "Fructose_1,6-bisphosphate_aldolase,_required_for_glycolysis_and_gluconeogenesis;_catalyzes_conversion_of_fructose_1,6_bisphosphate_to_glyceraldehyde-3-P_and_dihydroxyacetone-P;_locates_to_mitochondrial_outer_surface_upon_oxidative_stress" YKL061W None None biological_process_unknown molecular_function_unknown endosome None None 11 325415 325756 YKL061W S000001544 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_endosome YKL062W MSN4 None response_to_stress* DNA_binding* cytoplasm* None None 11 322872 324764 YKL062W S000001545 "ORF,_Verified" "Transcriptional_activator_related_to_Msn2p;_activated_in_stress_conditions,_which_results_in_translocation_from_the_cytoplasm_to_the_nucleus;_binds_DNA_at_stress_response_elements_of_responsive_genes,_inducing_gene_expression" YKL063C None None biological_process_unknown molecular_function_unknown Golgi_apparatus None None 11 321162 320659 YKL063C S000001546 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_Golgi YKL065C YET1 None biological_process_unknown molecular_function_unknown endoplasmic_reticulum S None 11 316701 316081 YKL065C S000001548 "ORF,_Verified" "Endoplasmic_reticulum_transmembrane_protein;_may_interact_with_ribosomes,_based_on_co-purification_experiments;_homolog_of_human_BAP31_protein" YKL067W YNK1 NDK1 purine_nucleotide_biosynthesis* nucleoside_diphosphate_kinase_activity cytosol* G1 None 11 314456 314917 YKL067W S000001550 "ORF,_Verified" "Nucleoside_diphosphate_kinase,_catalyzes_the_transfer_of_gamma_phosphates_from_nucleoside_triphosphates,_usually_ATP,_to_nucleoside_diphosphates_by_a_mechanism_that_involves_formation_of_an_autophosphorylated_enzyme_intermediate" YKL068W NUP100 NSP100 mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 11 309843 312722 YKL068W S000001551 "ORF,_Verified" Subunit_of_the_nuclear_pore_complex_(NPC)_that_is_localized_to_both_sides_of_the_pore;_contains_a_repetitive_GLFG_motif_that_interacts_with_mRNA_export_factor_Mex67p_and_with_karyopherin_Kap95p;_homologous_to_Nup116p YKL069W None YKG9 biological_process_unknown molecular_function_unknown cytoplasm* S/G2 None 11 306929 307471 YKL069W S000001552 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus YKL070W None None biological_process_unknown molecular_function_unknown mitochondrion None Up 11 305855 306364 YKL070W S000001553 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YKL071W None None biological_process_unknown molecular_function_unknown cytoplasm None Up 11 304758 305528 YKL071W S000001554 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YKL072W STB6 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 299226 301526 YKL072W S000001555 "ORF,_Verified" Protein_that_binds_Sin3p_in_a_two-hybrid_assay YKL073W LHS1 SSI1|CER1 response_to_unfolded_protein* unfolded_protein_binding endoplasmic_reticulum_lumen None Up 11 296074 298719 YKL073W S000001556 "ORF,_Verified" "Molecular_chaperone_of_the_endoplasmic_reticulum_lumen,_involved_in_polypeptide_translocation_and_folding;_member_of_the_Hsp70_family;_localizes_to_the_lumen_of_the_ER;_regulated_by_the_unfolded_protein_response_pathway" YKL074C MUD2 None U2-type_nuclear_mRNA_branch_site_recognition "RNA_splicing_factor_activity,_transesterification_mechanism*" commitment_complex None None 11 295837 294254 YKL074C S000001557 "ORF,_Verified" "Protein_involved_in_early_pre-mRNA_splicing;_component_of_the_pre-mRNA-U1_snRNP_complex,_the_commitment_complex;_interacts_with_Msl5p/BBP_splicing_factor_and_Sub2p;_similar_to_metazoan_splicing_factor_U2AF65" YKL077W None None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) None None 11 291097 292275 YKL077W S000001560 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuole YKL078W DHR2 None ribosome_biogenesis RNA_helicase_activity nucleolus None None 11 288489 290696 YKL078W S000001561 "ORF,_Verified" "Predominantly_nucleolar_DEAH-box_ATP-dependent_RNA_helicase,_required_for_18S_rRNA_synthesis" YKL080W VMA5 VAT3|CSL5 vacuolar_acidification "hydrogen-transporting_ATPase_activity,_rotational_mechanism" vacuolar_membrane_(sensu_Fungi)* None None 11 284674 285852 YKL080W S000001563 "ORF,_Verified" "Subunit_C_of_the_eight-subunit_V1_peripheral_membrane_domain_of_vacuolar_H+-ATPase_(V-ATPase),_an_electrogenic_proton_pump_found_throughout_the_endomembrane_system;_required_for_the_V1_domain_to_assemble_onto_the_vacuolar_membrane" YKL081W TEF4 EFC1 translational_elongation translation_elongation_factor_activity mitochondrion* None Down 11 282535 284099 YKL081W S000001564 "ORF,_Verified" Translation_elongation_factor_EF-1_gamma YKL082C RRP14 None establishment_of_cell_polarity_(sensu_Fungi)* molecular_function_unknown nucleolus None None 11 281973 280669 YKL082C S000001565 "ORF,_Verified" "Essential_protein,_constituent_of_66S_pre-ribosomal_particles;_interacts_with_proteins_involved_in_ribosomal_biogenesis_and_cell_polarity;_member_of_the_SURF-6_family" YKL084W HOT13 None protein_import_into_mitochondrial_intermembrane_space molecular_function_unknown mitochondrial_intermembrane_space None None 11 280153 280503 YKL084W S000001567 "ORF,_Verified" "Mitochondrial_intermembrane_space_protein,_first_component_of_a_pathway_mediating_assembly_of_small_TIM_(Translocase_of_the_Inner_Membrane)_complexes_which_escort_hydrophobic_inner_membrane_proteins_en_route_to_the_TIM22_complex" YKL085W MDH1 None tricarboxylic_acid_cycle* L-malate_dehydrogenase_activity mitochondrial_matrix None None 11 278767 279771 YKL085W S000001568 "ORF,_Verified" "Mitochondrial_malate_dehydrogenase,_catalyzes_interconversion_of_malate_and_oxaloacetate;_involved_in_the_tricarboxylic_acid_(TCA)_cycle;_phosphorylated" YKL086W SRX1 None response_to_oxidative_stress "oxidoreductase_activity,_acting_on_sulfur_group_of_donors" cytoplasm* None Up 11 277925 278308 YKL086W S000001569 "ORF,_Verified" "Sulfiredoxin,_contributes_to_oxidative_stress_resistance_by_reducing_cysteine-sulfinic_acid_groups_in_the_peroxiredoxins_Tsa1p_and_Ahp1p_that_are_formed_upon_exposure_to_oxidants;_conserved_in_higher_eukaryotes" YKL087C CYT2 None cytochrome_c-heme_linkage holocytochrome-c_synthase_activity mitochondrial_intermembrane_space None None 11 277507 276833 YKL087C S000001570 "ORF,_Verified" "Cytochrome_c1_heme_lyase,_involved_in_maturation_of_cytochrome_c1,_which_is_a_subunit_of_the_mitochondrial_ubiquinol-cytochrome-c_reductase;_links_heme_covalently_to_apocytochrome_c1" YKL088W None None response_to_salt_stress* purine_nucleotide_binding* cytoplasm None None 11 274927 276642 YKL088W S000001571 "ORF,_Uncharacterized" "Predicted_phosphopantothenoylcysteine_decarboxylase,_may_be_involved_in_coenzyme_A_biosynthesis;_interacts_with_Sis2p_and_Vhs3p" YKL089W MIF2 None chromosome_segregation* centromeric_DNA_binding nucleus* G1 None 11 273038 274687 YKL089W S000001572 "ORF,_Verified" "Kinetochore_protein_with_homology_to_human_CENP-C,_required_for_structural_integrity_of_the_spindle_during_anaphase_spindle_elongation,_interacts_with_histones_H2A,_H2B,_and_H4,_phosphorylated_by_Ipl1p" YKL090W CUE2 None biological_process_unknown protein_binding cellular_component_unknown None None 11 271522 272853 YKL090W S000001573 "ORF,_Verified" "Protein_of_unknown_function;_has_two_CUE_domains_that_bind_ubiquitin,_which_may_facilitate_intramolecular_monoubiquitination" YKL091C None SFH1 biological_process_unknown molecular_function_unknown nucleus None None 11 270294 269362 YKL091C S000001574 "ORF,_Verified" "Putative_homolog_of_Sec14p,_which_is_a_phosphatidylinositol/phosphatidylcholine_transfer_protein_involved_in_lipid_metabolism;_localizes_to_the_nucleus" YKL092C BUD2 ERC25|CLA2 bipolar_bud_site_selection* signal_transducer_activity* intracellular None None 11 269103 265789 YKL092C S000001575 "ORF,_Verified" GTPase_activating_factor_for_Rsr1p/Bud1p_required_for_both_axial_and_bipolar_budding_patterns;_mutants_exhibit_random_budding_in_all_cell_types YKL093W MBR1 None aerobic_respiration molecular_function_unknown cellular_component_unknown None None 11 264433 265452 YKL093W S000001576 "ORF,_Verified" "Protein_involved_in_mitochondrial_functions_and_stress_response;_overexpression_suppresses_growth_defects_of_hap2,_hap3,_and_hap4_mutants" YKL094W YJU3 None biological_process_unknown serine_hydrolase_activity cytoplasm* None None 11 262993 263934 YKL094W S000001577 "ORF,_Verified" "Serine_hydrolase_with_sequence_similarity_to_monoglyceride_lipase_(MGL),_localizes_to_lipid_particles" YKL095W YJU2 CWC16 "nuclear_mRNA_splicing,_via_spliceosome" molecular_function_unknown nucleus None None 11 261921 262757 YKL095W S000001578 "ORF,_Verified" "Essential_protein_required_for_pre-mRNA_splicing;_associates_transiently_with_the_spliceosomal_NTC_(""nineteen_complex"")_and_acts_after_Prp2p_to_promote_the_first_catalytic_reaction_of_splicing" YKL096W CWP1 YJU1 cell_wall_organization_and_biogenesis structural_constituent_of_cell_wall cell_wall_(sensu_Fungi) S/G2 None 11 260776 261495 YKL096W S000001579 "ORF,_Verified" "Cell_wall_mannoprotein,_linked_to_a_beta-1,3-_and_beta-1,6-glucan_heteropolymer_through_a_phosphodiester_bond;_involved_in_cell_wall_organization" YKL096W-A CWP2 YKL097W-A|LPR1 cell_wall_organization_and_biogenesis* structural_constituent_of_cell_wall cell_wall_(sensu_Fungi) S/G2 None 11 258897 259175 YKL096W-A S000001956 "ORF,_Verified" "Covalently_linked_cell_wall_mannoprotein,_major_constituent_of_the_cell_wall;_plays_a_role_in_stabilizing_the_cell_wall;_involved_in_low_pH_resistance;_precursor_is_GPI-anchored" YKL098W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 256414 257487 YKL098W S000001581 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YKL098W_is_synthetically_sick_with_cdc13-1 YKL099C UTP11 None processing_of_20S_pre-rRNA snoRNA_binding small_nucleolar_ribonucleoprotein_complex None None 11 256116 255364 YKL099C S000001582 "ORF,_Verified" Subunit_of_U3-containing_Small_Subunit_(SSU)_processome_complex_involved_in_production_of_18S_rRNA_and_assembly_of_small_ribosomal_subunit YKL103C LAP4 API|YSC1|APE1 vacuolar_protein_catabolism aminopeptidase_I_activity vacuole_(sensu_Fungi) G1 Up 11 247326 245782 YKL103C S000001586 "ORF,_Verified" "Vacuolar_aminopeptidase,_often_used_as_a_marker_protein_in_studies_of_autophagy_and_cytosol_to_vacuole_targeting_(CVT)_pathway" YKL104C GFA1 None cell_wall_chitin_biosynthesis glutamine-fructose-6-phosphate_transaminase_(isomerizing)_activity cellular_component_unknown M/G1 None 11 245017 242864 YKL104C S000001587 "ORF,_Verified" "Glutamine-fructose-6-phosphate_amidotransferase,_catalyzes_the_formation_of_glucosamine-6-P_and_glutamate_from_fructose-6-P_and_glutamine_in_the_first_step_of_chitin_biosynthesis" YKL105C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 242227 238829 YKL105C S000001588 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YKL106W AAT1 None aspartate_biosynthesis* aspartate_transaminase_activity mitochondrion None None 11 237180 238535 YKL106W S000001589 "ORF,_Verified" "Mitochondrial_aspartate_aminotransferase,_catalyzes_the_conversion_of_oxaloacetate_to_aspartate_in_aspartate_and_asparagine_biosynthesis" YKL108W SLD2 DRC1 DNA_strand_elongation molecular_function_unknown replication_fork G1 None 11 234070 235431 YKL108W S000001591 "ORF,_Verified" "Protein_required_for_DNA_replication,_phosphorylated_in_S_phase_by_S-phase_cyclin-dependent_kinases_(Cdks),_phosphorylation_is_essential_for_DNA_replication_and_for_complex_formation_with_Dpb11p;_potential_Cdc28p_substrate" YKL109W HAP4 None transcription* transcriptional_activator_activity CCAAT-binding_factor_complex None None 11 231871 233535 YKL109W S000001592 "ORF,_Verified" "Subunit_of_the_heme-activated,_glucose-repressed_Hap2p/3p/4p/5p_CCAAT-binding_complex,_a_transcriptional_activator_and_global_regulator_of_respiratory_gene_expression;_provides_the_principal_activation_function_of_the_complex" YKL110C KTI12 TOT4 carbon_utilization enzyme_regulator_activity "DNA-directed_RNA_polymerase_II,_holoenzyme" None None 11 229524 228583 YKL110C S000001593 "ORF,_Verified" "Protein_that_plays_a_role,_with_Elongator_complex,_in_modification_of_wobble_nucleosides_in_tRNA;_involved_in_sensitivity_to_G1_arrest_induced_by_zymocin;_interacts_with_chromatin_throughout_the_genome;_also_interacts_with_Cdc19p" YKL112W ABF1 SBF1|REB2|OBF1|BAF1 chromatin_remodeling* DNA_binding* nucleus* None Up 11 226214 228409 YKL112W S000001595 "ORF,_Verified" "DNA_binding_protein_with_possible_chromatin-reorganizing_activity_involved_in_transcriptional_activation,_gene_silencing,_and_DNA_replication_and_repair" YKL113C RAD27 FEN1|RTH1|ERC11 DNA_repair* 5'-flap_endonuclease_activity nucleus G1 None 11 225519 224371 YKL113C S000001596 "ORF,_Verified" "5'_to_3'_exonuclease,_5'_flap_endonuclease,_required_for_Okazaki_fragment_processing_and_maturation_as_well_as_for_long-patch_base-excision_repair;_member_of_the_S._pombe_RAD2/FEN1_family" YKL114C APN1 None DNA_repair* DNA-(apurinic_or_apyrimidinic_site)_lyase_activity nucleus* None None 11 224099 222996 YKL114C S000001597 "ORF,_Verified" "Major_apurinic/apyrimidinic_endonuclease,_3'-repair_diesterase_involved_in_repair_of_DNA_damage_by_oxidation_and_alkylating_agents;_also_functions_as_a_3'-5'_exonuclease_to_repair_7,8-dihydro-8-oxodeoxyguanosine" YKL116C PRR1 None MAPKKK_cascade receptor_signaling_protein_serine/threonine_kinase_activity cytoplasm M/G1 None 11 222544 220988 YKL116C S000001599 "ORF,_Verified" "Serine/threonine_protein_kinase_that_inhibits_pheromone_induced_signalling_downstream_of_MAPK,_possibly_at_the_level_of_the_Ste12p_transcription_factor" YKL119C VPH2 VMA12|CLS10 protein_complex_assembly* molecular_function_unknown endoplasmic_reticulum_membrane None None 11 218861 218214 YKL119C S000001602 "ORF,_Verified" "Integral_membrane_protein_required_for_vacuolar_H+-ATPase_(V-ATPase)_function,_although_not_an_actual_component_of_the_V-ATPase_complex;_functions_in_the_assembly_of_the_V-ATPase;_localized_to_the_endoplasmic_reticulum_(ER)" YKL120W OAC1 None sulfate_transport* oxaloacetate_carrier_activity* mitochondrial_inner_membrane None None 11 216988 217962 YKL120W S000001603 "ORF,_Verified" "Mitochondrial_inner_membrane_transporter,_transports_oxaloacetate,_sulfate,_thiosulfate,_and_isopropylmalate;_member_of_the_mitochondrial_carrier_family" YKL124W SSH4 MLF4 biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 210237 211976 YKL124W S000001607 "ORF,_Verified" "Specificity_factor_required_for_Rsp5p-dependent_ubiquitination_and_sorting_of_cargo_proteins_at_the_multivesicular_body;_identified_as_a_high-copy_suppressor_of_a_SHR3_deletion,_increasing_steady-state_levels_of_amino_acid_permeases" YKL125W RRN3 None transcription_from_RNA_polymerase_I_promoter RNA_polymerase_I_transcription_factor_activity RNA_polymerase_I_transcription_factor_complex None None 11 207891 209774 YKL125W S000001608 "ORF,_Verified" Protein_required_for_transcription_of_rDNA_by_RNA_polymerase_I;_transcription_factor_independent_of_DNA_template;_involved_in_recruitment_of_RNA_polymerase_I_to_rDNA YKL126W YPK1 SLI2 protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity cytosol* None None 11 205351 207393 YKL126W S000001609 "ORF,_Verified" "Serine/threonine_protein_kinase_required_for_receptor-mediated_endocytosis;_involved_in_sphingolipid-mediated_and_cell_integrity_signaling_pathways;_localized_to_the_bud_neck,_cytosol_and_plasma_membrane;_homolog_of_mammalian_kinase_SGK" YKL127W PGM1 None glucose_1-phosphate_utilization* phosphoglucomutase_activity cytosol G1 None 11 203185 204897 YKL127W S000001610 "ORF,_Verified" "Phosphoglucomutase,_minor_isoform;_catalyzes_the_conversion_from_glucose-1-phosphate_to_glucose-6-phosphate,_which_is_a_key_step_in_hexose_metabolism" YKL128C PMU1 None biological_process_unknown molecular_function_unknown cytoplasm* None None 11 201415 200528 YKL128C S000001611 "ORF,_Verified" "Putative_phosphomutase,_contains_a_region_homologous_to_the_active_site_of_phosphomutases;_overexpression_suppresses_the_histidine_auxotrophy_of_an_ade3_ade16_ade17_triple_mutant_and_the_temperature_sensitivity_of_a_tps2_mutant" YKL129C MYO3 None cell_wall_organization_and_biogenesis* microfilament_motor_activity actin_cortical_patch None None 11 200163 196348 YKL129C S000001612 "ORF,_Verified" "One_of_two_type_I_myosins;_localizes_to_actin_cortical_patches;_deletion_of_MYO3_has_little_effect_on_growth,_but_myo3_myo5_double_deletion_causes_severe_defects_in_growth_and_actin_cytoskeleton_organization" YKL130C SHE2 None intracellular_mRNA_localization mRNA_binding cytoplasm G2/M None 11 196027 195287 YKL130C S000001613 "ORF,_Verified" RNA-binding_protein_that_binds_specific_mRNAs_and_interacts_with_She3p;_part_of_the_mRNA_localization_machinery_that_restricts_accumulation_of_certain_proteins_to_the_bud YKL132C RMA1 None biological_process_unknown tetrahydrofolylpolyglutamate_synthase_activity mitochondrion None None 11 194865 193573 YKL132C S000001615 "ORF,_Verified" "Putative_dihydrofolate_synthetase;_has_similarity_to_Fol3p_and_to_E._coli_folylpolyglutamate_synthetase/dihydrofolate_synthetase;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YKL133C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 193069 191678 YKL133C S000001616 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YKL134C OCT1_ None iron_ion_homeostasis* metallopeptidase_activity* mitochondrion None None 11 191441 189129 YKL134C S000001617 "ORF,_Verified" "Mitochondrial_intermediate_peptidase,_cleaves_N-terminal_residues_of_a_subset_of_proteins_upon_import,_after_their_cleavage_by_mitochondrial_processing_peptidase_(Mas1p-Mas2p);_may_contribute_to_mitochondrial_iron_homeostasis" YKL135C APL2 None vesicle-mediated_transport clathrin_binding AP-1_adaptor_complex None None 11 188645 186465 YKL135C S000001618 "ORF,_Verified" "Beta-adaptin,_large_subunit_of_the_clathrin-associated_protein_(AP-1)_complex;_binds_clathrin;_involved_in_clathrin-dependent_Golgi_protein_sorting" YKL137W CMC1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 185962 186297 YKL137W S000001620 "ORF,_Verified" "Evolutionarily_conserved_copper-binding_protein_of_the_mitochondrial_inner_membrane,_may_be_involved_in_delivering_copper_from_the_matrix_to_the_cytochrome_c_oxidase_complex;_contains_a_twin_CX9C_motif" YKL138C MRPL31 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 11 185686 185291 YKL138C S000001621 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YKL139W CTK1 None protein_amino_acid_phosphorylation* protein_kinase_activity* nucleus None None 11 182963 184549 YKL139W S000001622 "ORF,_Verified" "Catalytic_(alpha)_subunit_of_C-terminal_domain_kinase_I_(CTDK-I),_which_phosphorylates_both_RNA_pol_II_subunit_Rpo21p_to_affect_transcription_and_pre-mRNA_3'_end_processing,_and_ribosomal_protein_Rps2p_to_increase_translational_fidelity" YKL140W TGL1 YKL5 lipid_metabolism* lipase_activity* integral_to_membrane* None None 11 180784 182430 YKL140W S000001623 "ORF,_Verified" "Steryl_ester_hydrolase,_one_of_three_gene_products_(Yeh1p,_Yeh2p,_Tgl1p)_responsible_for_steryl_ester_hydrolase_activity_and_involved_in_sterol_homeostasis;_localized_to_lipid_particle_membranes" YKL141W SDH3 YKL4|CYB3 tricarboxylic_acid_cycle* succinate_dehydrogenase_(ubiquinone)_activity respiratory_chain_complex_II_(sensu_Eukaryota) None None 11 179672 180268 YKL141W S000001624 "ORF,_Verified" "Cytochrome_b_subunit_of_succinate_dehydrogenase_(Sdh1p,_Sdh2p,_Sdh3p,_Sdh4p),_which_couples_the_oxidation_of_succinate_to_the_transfer_of_electrons_to_ubiquinone" YKL142W MRP8 YKL3 protein_biosynthesis structural_constituent_of_ribosome mitochondrial_ribosome None None 11 178520 179179 YKL142W S000001625 "ORF,_Verified" "Putative_mitochondrial_ribosomal_protein,_has_similarity_to_E._coli_ribosomal_protein_S2" YKL143W LTV1 YKL2 response_to_osmotic_stress* molecular_function_unknown cytoplasm None None 11 176786 178177 YKL143W S000001626 "ORF,_Verified" "Component_of_the_GSE_complex,_which_is_required_for_proper_sorting_of_amino_acid_permease_Gap1p;_required_for_ribosomal_small_subunit_export_from_nucleus;_required_for_growth_at_low_temperature" YKL144C RPC25 YKL1 transcription_from_RNA_polymerase_III_promoter DNA-directed_RNA_polymerase_activity DNA-directed_RNA_polymerase_III_complex None None 11 176486 175848 YKL144C S000001627 "ORF,_Verified" "RNA_polymerase_III_subunit_C25,_required_for_transcription_initiation;_forms_a_heterodimer_with_Rpc17p;_paralog_of_Rpb7p" YKL145W RPT1 YTA3|CIM5 ubiquitin-dependent_protein_catabolism ATPase_activity* "proteasome_regulatory_particle,_base_subcomplex_(sensu_Eukaryota)" None None 11 174218 175621 YKL145W S000001628 "ORF,_Verified" One_of_six_ATPases_of_the_19S_regulatory_particle_of_the_26S_proteasome_involved_in_the_degradation_of_ubiquitinated_substrates;_required_for_optimal_CDC20_transcription;_interacts_with_Rpn12p_and_the_E3_ubiquitin-protein_ligase_Ubr1p YKL148C SDH1 None tricarboxylic_acid_cycle* succinate_dehydrogenase_(ubiquinone)_activity respiratory_chain_complex_II_(sensu_Eukaryota) None None 11 171134 169212 YKL148C S000001631 "ORF,_Verified" "Flavoprotein_subunit_of_succinate_dehydrogenase_(Sdh1p,_Sdh2p,_Sdh3p,_Sdh4p),_which_couples_the_oxidation_of_succinate_to_the_transfer_of_electrons_to_ubiquinone" YKL149C DBR1 PRP26 snoRNA_metabolism* RNA_lariat_debranching_enzyme_activity nucleus None None 11 168834 167617 YKL149C S000001632 "ORF,_Verified" "RNA_lariat_debranching_enzyme,_involved_in_intron_turnover;_required_for_efficient_Ty1_transposition" YKL150W MCR1 None response_to_oxidative_stress* cytochrome-b5_reductase_activity mitochondrial_outer_membrane* None None 11 166549 167457 YKL150W S000001633 "ORF,_Verified" "Mitochondrial_NADH-cytochrome_b5_reductase,_involved_in_ergosterol_biosynthesis" YKL152C GPM1 None glycolysis* phosphoglycerate_mutase_activity cytosol None None 11 164390 163647 YKL152C S000001635 "ORF,_Verified" "Tetrameric_phosphoglycerate_mutase,_mediates_the_conversion_of_3-phosphoglycerate_to_2-phosphoglycerate_during_glycolysis_and_the_reverse_reaction_during_gluconeogenesis" YKL154W SRP102 None protein_targeting_to_ER* GTPase_activity* integral_to_endoplasmic_reticulum_membrane* None None 11 161606 162340 YKL154W S000001637 "ORF,_Verified" Signal_recognition_particle_(SRP)_receptor_beta_subunit;_involved_in_SRP-dependent_protein_targeting;_anchors_Srp101p_to_the_ER_membrane YKL156W RPS27A None protein_biosynthesis structural_constituent_of_ribosome cytoplasm* None None 11 158619 159217 YKL156W S000001639 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps27Bp_and_has_similarity_to_rat_S27_ribosomal_protein YKL157W APE2 YKL158W|LAP1 peptide_metabolism leucyl_aminopeptidase_activity cytoplasm* None None 11 154996 158186 YKL157W S000001640 "ORF,_Verified" Aminopeptidase_yscII;_may_have_a_role_in_obtaining_leucine_from_dipeptide_substrates;_sequence_coordinates_have_changed_since_RT-PCR_analysis_showed_that_the_adjacent_ORF_YKL158W_comprises_the_5'_exon_of_APE2/YKL157W YKL159C RCN1 None calcium-mediated_signaling calcium-dependent_protein_serine/threonine_phosphatase_regulator_activity calcineurin_complex None None 11 154456 153821 YKL159C S000001642 "ORF,_Verified" Protein_involved_in_calcineurin_regulation_during_calcium_signaling;_has_similarity_to_H._sapiens_DSCR1_which_is_found_in_the_Down_Syndrome_candidate_region YKL160W ELF1 None RNA_elongation_from_RNA_polymerase_II_promoter* RNA_polymerase_II_transcription_elongation_factor_activity nucleus None None 11 153274 153711 YKL160W S000001643 "ORF,_Verified" Transcription_elongation_factor_that_contains_a_conserved_zinc_finger_domain;_implicated_in_the_maintenance_of_proper_chromatin_structure_in_actively_transcribed_regions;_deletion_inhibits_Brome_mosaic_virus_(BMV)_gene_expression YKL161C None MLP1 biological_process_unknown protein_kinase_activity cellular_component_unknown None None 11 150692 149391 YKL161C S000001644 "ORF,_Verified" Protein_kinase_implicated_in_the_Slt2p_mitogen-activated_(MAP)_kinase_signaling_pathway;_associates_with_Rlm1p YKL162C None None biological_process_unknown molecular_function_unknown mitochondrion None None 11 148843 147635 YKL162C S000001645 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_mitochondrion YKL163W PIR3 CCW8 cell_wall_organization_and_biogenesis structural_constituent_of_cell_wall cell_wall_(sensu_Fungi) M/G1 None 11 144406 145383 YKL163W S000001646 "ORF,_Verified" "O-glycosylated_covalently-bound_cell_wall_protein_required_for_cell_wall_stability;_expression_is_cell_cycle_regulated,_peaking_in_M/G1_and_also_subject_to_regulation_by_the_cell_integrity_pathway" YKL164C PIR1 CCW6 cell_wall_organization_and_biogenesis* structural_constituent_of_cell_wall cell_wall_(sensu_Fungi) M/G1 None 11 142824 141799 YKL164C S000001647 "ORF,_Verified" "O-glycosylated_protein_required_for_cell_wall_stability;_attached_to_the_cell_wall_via_beta-1,3-glucan;_mediates_mitochondrial_translocation_of_Apn1p;_expression_regulated_by_the_cell_integrity_pathway_and_by_Swi5p_during_the_cell_cycle" YKL165C MCD4 FSR2|SSU21|ZRG16 GPI_anchor_biosynthesis* molecular_function_unknown endoplasmic_reticulum* G1 None 11 140696 137937 YKL165C S000001648 "ORF,_Verified" Protein_involved_in_glycosylphosphatidylinositol_(GPI)_anchor_synthesis;_multimembrane-spanning_protein_that_localizes_to_the_endoplasmic_reticulum;_highly_conserved_among_eukaryotes YKL166C TPK3 None protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity* cytoplasm* None None 11 135710 134514 YKL166C S000001649 "ORF,_Verified" cAMP-dependent_protein_kinase_catalytic_subunit;_promotes_vegetative_growth_in_response_to_nutrients_via_the_Ras-cAMP_signaling_pathway;_inhibited_by_regulatory_subunit_Bcy1p_in_the_absence_of_cAMP;_partially_redundant_with_Tpk1p_and_Tpk2p YKL167C MRP49 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 11 134139 133726 YKL167C S000001650 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_large_subunit,_not_essential_for_mitochondrial_translation" YKL170W MRPL38 MRPL34 protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 11 130639 131055 YKL170W S000001653 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit;_appears_as_two_protein_spots_(YmL34_and_YmL38)_on_two-dimensional_SDS_gels YKL171W None None proteolysis protein_kinase_activity cytoplasm None None 11 127480 130266 YKL171W S000001654 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_predicted_protein_kinase;_implicated_in_proteasome_function;_epitope-tagged_protein_localizes_to_the_cytoplasm YKL172W EBP2 None rRNA_processing* molecular_function_unknown nucleolus G2/M None 11 125764 127047 YKL172W S000001655 "ORF,_Verified" "Essential_protein_required_for_the_maturation_of_25S_rRNA_and_60S_ribosomal_subunit_assembly,_localizes_to_the_nucleolus;_constituent_of_66S_pre-ribosomal_particles" YKL173W SNU114 GIN10 "nuclear_mRNA_splicing,_via_spliceosome*" GTPase_activity* U4/U6_x_U5_tri-snRNP_complex* None Up 11 122522 125548 YKL173W S000001656 "ORF,_Verified" GTPase_component_of_U5_snRNP_involved_in_mRNA_splicing_via_spliceosome;_binds_directly_to_U5_snRNA;_proposed_to_be_involved_in_conformational_changes_of_the_spliceosome;_similarity_to_ribosomal_translocation_factor_EF-2 YKL175W ZRT3 None zinc_ion_homeostasis* zinc_ion_transporter_activity vacuolar_membrane None None 11 118798 120309 YKL175W S000001658 "ORF,_Verified" "Vacuolar_membrane_zinc_transporter,_transports_zinc_from_storage_in_the_vacuole_to_the_cytoplasm_when_needed;_transcription_is_induced_under_conditions_of_zinc_deficiency" YKL176C LST4 None vesicle-mediated_transport* protein_transporter_activity vesicle_coat None None 11 117991 115505 YKL176C S000001659 "ORF,_Verified" Protein_possibly_involved_in_a_post-Golgi_secretory_pathway;_required_for_the_transport_of_nitrogen-regulated_amino_acid_permease_Gap1p_from_the_Golgi_to_the_cell_surface YKL178C STE3 DAF2 signal_transduction_during_conjugation_with_cellular_fusion mating-type_a-factor_pheromone_receptor_activity integral_to_plasma_membrane M/G1 None 11 114632 113220 YKL178C S000001661 "ORF,_Verified" "Receptor_for_a_factor_receptor,_transcribed_in_alpha_cells_and_required_for_mating_by_alpha_cells,_couples_to_MAP_kinase_cascade_to_mediate_pheromone_response;_ligand_bound_receptors_are_endocytosed_and_recycled_to_the_plasma_membrane;_GPCR" YKL180W RPL17A RPL17 protein_biosynthesis structural_constituent_of_ribosome cytoplasm* None None 11 109274 110134 YKL180W S000001663 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl17Bp_and_has_similarity_to_E._coli_L22_and_rat_L17_ribosomal_proteins;_copurifies_with_the_Dam1_complex_(aka_DASH_complex)" YKL181W PRS1 PRP1 histidine_biosynthesis* ribose_phosphate_diphosphokinase_activity cytoplasm None None 11 107321 108604 YKL181W S000001664 "ORF,_Verified" "5-phospho-ribosyl-1(alpha)-pyrophosphate_synthetase,_synthesizes_PRPP,_which_is_required_for_nucleotide,_histidine,_and_tryptophan_biosynthesis;_one_of_five_related_enzymes,_which_are_active_as_heteromultimeric_complexes" YKL182W FAS1 None fatty_acid_biosynthesis [acyl-carrier_protein]_S-malonyltransferase_activity* mitochondrion* M/G1 None 11 100676 106831 YKL182W S000001665 "ORF,_Verified" "Beta_subunit_of_fatty_acid_synthetase,_which_catalyzes_the_synthesis_of_long-chain_saturated_fatty_acids;_contains_acetyltransacylase,_dehydratase,_enoyl_reductase,_malonyl_transacylase,_and_palmitoyl_transacylase_activities" YKL183W LOT5 None biological_process_unknown molecular_function_unknown cytoplasm* S/G2 None 11 98726 99646 YKL183W S000001666 "ORF,_Verified" Protein_of_unknown_function;_gene_expression_increases_in_cultures_shifted_to_a_lower_temperature YKL186C MTR2 None poly(A)+_mRNA_export_from_nucleus protein_binding nuclear_pore None None 11 93303 92749 YKL186C S000001669 "ORF,_Verified" "mRNA_transport_regulator,_essential_nuclear_protein;_Mex67p_and_Mtr2p_form_a_mRNA_export_complex_which_binds_to_RNA" YKL187C None None biological_process_unknown molecular_function_unknown mitochondrion None None 11 91541 89289 YKL187C S000001670 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_a_phosphorylated_state_in_highly_purified_mitochondria_in_high-throughput_studies" YKL189W HYM1 None regulation_of_transcription* molecular_function_unknown intracellular* None None 11 84709 85908 YKL189W S000001672 "ORF,_Verified" "Component_of_the_RAM_signaling_network_that_is_involved_in_regulation_of_Ace2p_activity_and_cellular_morphogenesis,_interacts_with_Kic1p_and_Sog2p,_localizes_to_sites_of_polarized_growth_during_budding_and_during_the_mating_response" YKL191W DPH2 None peptidyl-diphthamide_biosynthesis_from_peptidyl-histidine molecular_function_unknown cytoplasm None None 11 81040 82644 YKL191W S000001674 "ORF,_Verified" "Protein_required,_along_with_Dph1p,_Kti11p,_Jjj3p,_and_Dph5p,_for_synthesis_of_diphthamide,_which_is_a_modified_histidine_residue_of_translation_elongation_factor_2_(Eft1p_or_Eft2p);_may_act_in_a_complex_with_Dph1p_and_Kti11p" YKL192C ACP1 None fatty_acid_biosynthesis acyl_carrier_activity mitochondrion None None 11 80542 80165 YKL192C S000001675 "ORF,_Verified" "Mitochondrial_matrix_acyl_carrier_protein,_involved_in_biosynthesis_of_octanoate,_which_is_a_precursor_to_lipoic_acid;_activated_by_phosphopantetheinylation_catalyzed_by_Ppt2p" YKL195W MIA40 TIM40|FMP15 protein_targeting* molecular_function_unknown mitochondrion* None None 11 75826 77037 YKL195W S000001678 "ORF,_Verified" Essential_protein_of_the_mitochondrial_intermembrane_space_(IMS);_promotes_retention_of_newly_imported_proteins;_may_do_so_by_stabilizing_client_protein_folding_as_part_of_a_disulfide_relay_system_or_transferring_metal_to_client_proteins YKL196C YKT6 None vesicle_fusion* v-SNARE_activity* mitochondrion* None None 11 75539 74937 YKL196C S000001679 "ORF,_Verified" "Vesicle_membrane_protein_(v-SNARE)_with_acyltransferase_activity;_involved_in_trafficking_to_and_within_the_Golgi,_endocytic_trafficking_to_the_vacuole,_and_vacuolar_fusion;_membrane_localization_due_to_prenylation_at_the_carboxy-terminus" YKL197C PEX1 PAS1 peroxisome_organization_and_biogenesis ATPase_activity peroxisome None None 11 73870 70739 YKL197C S000001680 "ORF,_Verified" AAA-peroxin_that_heterodimerizes_with_AAA-peroxin_Pex6p_and_participates_in_the_recycling_of_peroxisomal_signal_receptor_Pex5p_from_the_peroxisomal_membrane_to_the_cystosol;_induced_by_oleic_acid_and_upregulated_during_anaerobiosis YKL198C PTK1 POT1|YKT9|YKL199C|STK1|KKT8 polyamine_transport protein_kinase_activity cellular_component_unknown None None 11 70223 68274 YKL198C S000001681 "ORF,_Verified" Putative_serine/threonine_protein_kinase_that_regulates_spermine_uptake;_involved_in_polyamine_transport;_possible_mitochondrial_protein YKL203C TOR2 DRR2 endocytosis* protein_binding* mitochondrion* None None 11 63360 55936 YKL203C S000001686 "ORF,_Verified" "PIK-related_protein_kinase_and_rapamycin_target;_subunit_of_TORC1,_a_complex_that_regulates_growth_in_response_to_nutrients_and_TORC2,_a_complex_that_regulates_cell-cycle_dependent_polarization_of_the_actin_cytoskeleton;_involved_in_meiosis" YKL205W LOS1 None tRNA_export_from_nucleus* tRNA_binding* mitochondrion* None None 11 50052 53354 YKL205W S000001688 "ORF,_Verified" Nuclear_pore_protein_involved_in_nuclear_export_of_pre-tRNA YKL206C ADD66 POC2|PBA2 biological_process_unknown molecular_function_unknown cytoplasm None None 11 49810 49007 YKL206C S000001689 "ORF,_Verified" Protein_involved_in_20S_proteasome_assembly;_forms_a_heterodimer_with_Pba1p_that_binds_to_proteasome_precursors;_similar_to_human_PAC2_constituent_of_the_PAC1-PAC2_complex_involved_in_proteasome_assembly YKL207W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 48195 48956 YKL207W S000001690 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene;_null_mutant_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation)_and_severe_growth_defect_in_minimal_glycerol_media YKL208W CBT1 SOC1 mRNA_processing* molecular_function_unknown mitochondrion None None 11 47158 47973 YKL208W S000001691 "ORF,_Verified" "Protein_involved_in_5'_end_processing_of_mitochondrial_COB,_15S_rRNA,_and_RPM1_transcripts;_may_also_have_a_role_in_3'_end_processing_of_the_COB_pre-mRNA;_displays_genetic_interaction_with_cell_cycle-regulated_kinase_Dbf2p" YKL210W UBA1 None ubiquitin_cycle ubiquitin_activating_enzyme_activity cytoplasm* None Up 11 39164 42238 YKL210W S000001693 "ORF,_Verified" "Ubiquitin_activating_enzyme_(E1),_involved_in_ubiquitin-mediated_protein_degradation_and_essential_for_viability" YKL213C DOA1 ZZZ4|UFD3 ubiquitin-dependent_protein_catabolism* molecular_function_unknown cytoplasm* None None 11 34108 31961 YKL213C S000001696 "ORF,_Verified" "WD_repeat_protein_required_for_ubiquitin-mediated_protein_degradation,_forms_complex_with_Cdc48p,_plays_a_role_in_controlling_cellular_ubiquitin_concentration;_also_promotes_efficient_NHEJ_in_postdiauxic/stationary_phase" YKL214C YRA2 None poly(A)+_mRNA_export_from_nucleus RNA_binding nucleus None None 11 31694 31083 YKL214C S000001697 "ORF,_Verified" "Member_of_the_REF_(RNA_and_export_factor_binding_proteins)_family;_when_overexpressed,_can_substitute_for_the_function_of_Yra1p_in_export_of_poly(A)+_mRNA_from_the_nucleus" YKL216W URA1 None de_novo'_pyrimidine_base_biosynthesis dihydroorotate_dehydrogenase_activity cytoplasm None Down 11 25216 26160 YKL216W S000001699 "ORF,_Verified" "Dihydroorotate_dehydrogenase,_catalyzes_the_fourth_enzymatic_step_in_the_de_novo_biosynthesis_of_pyrimidines,_converting_dihydroorotic_acid_into_orotic_acid" YKL218C SRY1 None amino_acid_derivative_catabolism threo-3-hydroxyaspartate_ammonia-lyase_activity* cellular_component_unknown None Up 11 18339 17359 YKL218C S000001701 "ORF,_Verified" "3-hydroxyaspartate_dehydratase,_deaminates_L-threo-3-hydroxyaspartate_to_form_oxaloacetate_and_ammonia;_required_for_survival_in_the_presence_of_hydroxyaspartate" YKL219W COS9 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 14485 15708 YKL219W S000001702 "ORF,_Verified" "Protein_of_unknown_function,_member_of_the_DUP380_subfamily_of_conserved,_often_subtelomerically-encoded_proteins" YKL221W MCH2 None transport transporter_activity* membrane None None 11 6108 7529 YKL221W S000001704 "ORF,_Verified" "Protein_with_similarity_to_mammalian_monocarboxylate_permeases,_which_are_involved_in_transport_of_monocarboxylic_acids_across_the_plasma_membrane;_mutant_is_not_deficient_in_monocarboxylate_transport" YKL222C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 5621 3504 YKL222C S000001705 "ORF,_Verified" "Protein_of_unknown_function_that_may_interact_with_ribosomes,_based_on_co-purification_experiments;_similar_to_transcriptional_regulators_from_the_zinc_cluster_(binuclear_cluster)_family;_null_mutant_is_sensitive_to_caffeine" YKL224C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 2182 1811 YKL224C S000001707 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YKR001C VPS1 VPT26|VPL1|SPO15|LAM1|GRD1 protein_targeting_to_vacuole* GTPase_activity cytoplasm* None None 11 442365 440251 YKR001C S000001709 "ORF,_Verified" "Dynamin-like_GTPase_required_for_vacuolar_sorting;_also_involved_in_actin_cytoskeleton_organization,_late_Golgi-retention_of_some_proteins,_regulating_peroxisome_biogenesis" YKR003W OSH6 None steroid_biosynthesis oxysterol_binding cellular_component_unknown None None 11 445024 446370 YKR003W S000001711 "ORF,_Verified" "Member_of_an_oxysterol-binding_protein_family_with_overlapping,_redundant_functions_in_sterol_metabolism_and_which_collectively_perform_a_function_essential_for_viability;_GFP-fusion_protein_localizes_to_the_cell_periphery" YKR006C MRPL13 YK105 protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 11 450860 450066 YKR006C S000001714 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_large_subunit,_not_essential_for_mitochondrial_translation" YKR007W MEH1 GSE2|EGO1 vacuolar_acidification* molecular_function_unknown vacuolar_membrane_(sensu_Fungi)* None None 11 451077 451631 YKR007W S000001715 "ORF,_Verified" "Component_of_the_EGO_complex,_which_is_involved_in_the_regulation_of_microautophagy,_and_of_the_GSE_complex,_which_is_required_for_proper_sorting_of_amino_acid_permease_Gap1p;_loss_results_in_a_defect_in_vacuolar_acidification" YKR008W RSC4 None chromatin_remodeling molecular_function_unknown RSC_complex None Up 11 451844 453721 YKR008W S000001716 "ORF,_Verified" Component_of_the_RSC_chromatin_remodeling_complex;_found_in_close_proximity_to_nucleosomal_DNA;_displaced_from_the_surface_of_nucleosomal_DNA_after_chromatin_remodeling YKR009C FOX2 POX2 fatty_acid_beta-oxidation 3-hydroxyacyl-CoA_dehydrogenase_activity* peroxisomal_matrix None Up 11 456697 453995 YKR009C S000001717 "ORF,_Verified" Multifunctional_enzyme_of_the_peroxisomal_fatty_acid_beta-oxidation_pathway;_has_3-hydroxyacyl-CoA_dehydrogenase_and_enoyl-CoA_hydratase_activities YKR013W PRY2 YFW12 biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi)* G1 None 11 463602 464591 YKR013W S000001721 "ORF,_Verified" "Protein_of_unknown_function,_has_similarity_to_Pry1p_and_Pry3p_and_to_the_plant_PR-1_class_of_pathogen_related_proteins" YKR014C YPT52 None endocytosis* GTPase_activity late_endosome None None 11 465714 465010 YKR014C S000001722 "ORF,_Verified" "GTPase,_similar_to_Ypt51p_and_Ypt53p_and_to_mammalian_rab5;_required_for_vacuolar_protein_sorting_and_endocytosis" YKR016W None FMP13 biological_process_unknown molecular_function_unknown mitochondrion None None 11 469360 470982 YKR016W S000001724 "ORF,_Uncharacterized" Protein_of_unknown_function;_non-tagged_protein_is_detected_in_purified_mitochondria_in_high-throughput_studies;_null_mutant_displays_decreased_frequency_of_mitochondrial_genome_loss_and_severe_growth_defect_in_minimal_glycerol_media YKR017C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 11 472992 471337 YKR017C S000001725 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_contains_a_RING_finger_motif YKR018C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 11 475543 473366 YKR018C S000001726 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus YKR019C IRS4 None cell_wall_organization_and_biogenesis* molecular_function_unknown mitochondrion None None 11 477706 475859 YKR019C S000001727 "ORF,_Verified" "EH_domain-containing_protein_involved_in_regulating_phosphatidylinositol_4,5-bisphosphate_levels_and_autophagy;_Irs4p_and_Tax4p_bind_and_activate_the_PtdIns_phosphatase_Inp51p;_Irs4p_and_Tax4p_are_involved_in_localizing_Atg17p_to_the_PAS" YKR020W VPS51 VPS67|API3|WHI6 protein_targeting_to_vacuole* protein_binding Golgi_apparatus* None None 11 477981 478475 YKR020W S000001728 "ORF,_Verified" "Component_of_the_GARP_(Golgi-associated_retrograde_protein)_complex,_Vps51p-Vps52p-Vps53p-Vps54p,_which_is_required_for_the_recycling_of_proteins_from_endosomes_to_the_late_Golgi;_links_the_(VFT/GARP)_complex_to_the_SNARE_Tlg1p" YKR021W ALY1 None biological_process_unknown molecular_function_unknown cytoplasm G2/M None 11 478877 481624 YKR021W S000001729 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YKR023W None None biological_process_unknown molecular_function_unknown cytoplasm* None Up 11 483062 484654 YKR023W S000001731 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YKR025W RPC37 None transcription_from_RNA_polymerase_III_promoter DNA-directed_RNA_polymerase_activity DNA-directed_RNA_polymerase_III_complex None None 11 487413 488261 YKR025W S000001733 "ORF,_Verified" RNA_polymerase_III_subunit_C37 YKR027W BCH2 FMP50 biological_process_unknown molecular_function_unknown mitochondrion* None None 11 491007 493304 YKR027W S000001735 "ORF,_Verified" "Member_of_the_ChAPs_family_of_proteins_(Chs5p-Arf1p-binding_proteins:_Bch1p,_Bch2p,_Bud7p,_Chs6p),_that_forms_the_exomer_complex_with_Chs5p_to_mediate_export_of_specific_cargo_proteins,_including_Chs3p,_from_the_Golgi_to_the_plasma_membrane" YKR029C SET3 None histone_deacetylation* NAD-dependent_histone_deacetylase_activity* histone_deacetylase_complex None None 11 499475 497220 YKR029C S000001737 "ORF,_Verified" Defining_member_of_the_SET3_histone_deacetylase_complex_which_is_a_meiosis-specific_repressor_of_sporulation_genes;_necessary_for_efficient_transcription_by_RNAPII;_one_of_two_yeast_proteins_that_contains_both_SET_and_PHD_domains YKR030W GMH1 MSG1 transport molecular_function_unknown integral_to_Golgi_membrane None None 11 499924 500745 YKR030W S000001738 "ORF,_Verified" "Golgi_membrane_protein_of_unknown_function,_interacts_with_Gea1p_and_Gea2p;_required_for_localization_of_Gea2p;_computational_analysis_suggests_a_possible_role_in_either_cell_wall_synthesis_or_protein-vacuolar_targeting" YKR031C SPO14 PLD1 sporulation_(sensu_Fungi)* phospholipase_D_activity endosome* None None 11 506037 500986 YKR031C S000001739 "ORF,_Verified" "Phospholipase_D,_catalyzes_the_hydrolysis_of_phosphatidylcholine,_producing_choline_and_phosphatidic_acid;_involved_in_Sec14p-independent_secretion;_required_for_meiosis_and_spore_formation;_differently_regulated_in_secretion_and_meiosis" YKR034W DAL80 UGA43 transcription* transcription_factor_activity nucleus None None 11 506540 507349 YKR034W S000001742 "ORF,_Verified" "Negative_regulator_of_genes_in_multiple_nitrogen_degradation_pathways;_expression_is_regulated_by_nitrogen_levels_and_by_Gln3p;_member_of_the_GATA-binding_family,_forms_homodimers_and_heterodimers_with_Deh1p" YKR035W-A DID2 VPS46|CHM1|FTI1 protein_targeting_to_vacuole* molecular_function_unknown cytoplasm* None None 11 507581 508195 YKR035W-A S000006435 "ORF,_Verified" Class_E_protein_of_the_vacuolar_protein-sorting_(Vps)_pathway;_binds_Vps4p_and_directs_it_to_dissociate_ESCRT-III_complexes;_forms_a_functional_and_physical_complex_with_Ist1p;_human_ortholog_may_be_altered_in_breast_tumors YKR036C CAF4 None "regulation_of_transcription,_DNA-dependent" protein_binding mitochondrion* None None 11 510275 508344 YKR036C S000001744 "ORF,_Verified" "WD40_repeat-containing_protein_associated_with_the_CCR4-NOT_complex,_interacts_in_a_Ccr4p-dependent_manner_with_Ssn2p;_also_interacts_with_Fis1p,_Mdv1p_and_Dnm1p_and_plays_a_role_in_mitochondrial_fission" YKR037C SPC34 None mitotic_spindle_organization_and_biogenesis_in_nucleus* structural_constituent_of_cytoskeleton spindle_pole_body* S None 11 511439 510552 YKR037C S000001745 "ORF,_Verified" "Essential_subunit_of_the_Dam1_complex_(aka_DASH_complex),_couples_kinetochores_to_the_force_produced_by_MT_depolymerization_thereby_aiding_in_chromosome_segregation;_also_localized_to_nuclear_side_of_spindle_pole_body" YKR039W GAP1 None amino_acid_transport* L-proline_permease_activity* plasma_membrane* S/G2 None 11 514705 516513 YKR039W S000001747 "ORF,_Verified" General_amino_acid_permease;_localization_to_the_plasma_membrane_is_regulated_by_nitrogen_source YKR042W UTH1 None mitochondrion_organization_and_biogenesis* molecular_function_unknown cell_wall_(sensu_Fungi)* G2/M None 11 519169 520266 YKR042W S000001750 "ORF,_Verified" "Mitochondrial_outer_membrane_and_cell_wall_localized_SUN_family_member_required_for_mitochondrial_autophagy;_involved_in_the_oxidative_stress_response,_life_span_during_starvation,_mitochondrial_biogenesis,_and_cell_death" YKR043C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 11 521354 520539 YKR043C S000001751 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_nucleus YKR045C None None biological_process_unknown molecular_function_unknown cytoplasm None None 11 523611 523060 YKR045C S000001753 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_epitope-tagged_protein_localizes_to_the_cytoplasm YKR046C PET10 None aerobic_respiration molecular_function_unknown lipid_particle G2/M Up 11 524716 523865 YKR046C S000001754 "ORF,_Verified" Protein_of_unknown_function_that_co-purifies_with_lipid_particles;_expression_pattern_suggests_a_role_in_respiratory_growth;_computational_analysis_of_large-scale_protein-protein_interaction_data_suggests_a_role_in_ATP/ADP_exchange YKR049C FMP46 None biological_process_unknown oxidoreductase_activity mitochondrion None None 11 526873 526472 YKR049C S000001757 "ORF,_Verified" "Putative_redox_protein_containing_a_thioredoxin_fold;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YKR050W TRK2 RPD2 potassium_ion_homeostasis potassium_ion_transporter_activity plasma_membrane None None 11 527457 530126 YKR050W S000001758 "ORF,_Verified" Component_of_the_Trk1p-Trk2p_potassium_transport_system YKR052C MRS4 None RNA_splicing* iron_ion_transporter_activity* mitochondrion None None 11 533106 532192 YKR052C S000001760 "ORF,_Verified" "Mitochondrial_iron_transporter_of_the_mitochondrial_carrier_family_(MCF),_very_similar_to_and_functionally_redundant_with_Mrs3p;_functions_under_low-iron_conditions;_may_transport_other_cations_in_addition_to_iron" YKR053C YSR3 LBP2 sphingolipid_biosynthesis sphingosine-1-phosphate_phosphatase_activity endoplasmic_reticulum None None 11 534923 533709 YKR053C S000001761 "ORF,_Verified" "Dihydrosphingosine_1-phosphate_phosphatase,_membrane_protein_involved_in_sphingolipid_metabolism;_has_similarity_to_Lcb3p" YKR056W TRM2 RNC1|NUD1|NUC2 tRNA_modification tRNA_(m5U54)_methyltransferase_activity cellular_component_unknown None None 11 549090 551009 YKR056W S000001764 "ORF,_Verified" "tRNA_methyltransferase,_5-methylates_the_uridine_residue_at_position_54_of_tRNAs_and_may_also_have_a_role_in_tRNA_stabilization_or_maturation;_endo-exonuclease_with_a_role_in_DNA_repair" YKR057W RPS21A RPS25 protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 11 551299 551884 YKR057W S000001765 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps21Bp_and_has_similarity_to_rat_S21_ribosomal_protein YKR058W GLG1 None glycogen_biosynthesis glycogenin_glucosyltransferase_activity cellular_component_unknown None None 11 552412 554262 YKR058W S000001766 "ORF,_Verified" "Self-glucosylating_initiator_of_glycogen_synthesis,_also_glucosylates_n-dodecyl-beta-D-maltoside;_similar_to_mammalian_glycogenin" YKR059W TIF1 None translational_initiation translation_initiation_factor_activity ribosome* None None 11 554629 555816 YKR059W S000001767 "ORF,_Verified" "Translation_initiation_factor_eIF4A,_identical_to_Tif2p;_DEA(D/H)-box_RNA_helicase_that_couples_ATPase_activity_to_RNA_binding_and_unwinding;_forms_a_dumbbell_structure_of_two_compact_domains_connected_by_a_linker;_interacts_with_eIF4G" YKR060W UTP30 None 35S_primary_transcript_processing snoRNA_binding nucleus* None None 11 556160 556984 YKR060W S000001768 "ORF,_Verified" "Possible_U3_snoRNP_protein_involved_in_maturation_of_pre-18S_rRNA,_based_on_computational_analysis_of_large-scale_protein-protein_interaction_data" YKR061W KTR2 None protein_amino_acid_N-linked_glycosylation* mannosyltransferase_activity Golgi_apparatus None None 11 557319 558596 YKR061W S000001769 "ORF,_Verified" Mannosyltransferase_involved_in_N-linked_protein_glycosylation;_member_of_the_KRE2/MNT1_mannosyltransferase_family YKR062W TFA2 None transcription_initiation_from_RNA_polymerase_II_promoter general_RNA_polymerase_II_transcription_factor_activity transcription_factor_TFIIE_complex None None 11 559308 560294 YKR062W S000001770 "ORF,_Verified" "TFIIE_small_subunit,_involved_in_RNA_polymerase_II_transcription_initiation" YKR064W OAF3 None biological_process_unknown molecular_function_unknown cytoplasm* None None 11 562189 564780 YKR064W S000001772 "ORF,_Verified" "Zinc_cluster_protein;_regulates_transcription_in_response_to_oleate_levels;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YKR065C PAM17 FMP18 protein_import_into_mitochondrial_matrix molecular_function_unknown mitochondrion* None None 11 565534 564941 YKR065C S000001773 "ORF,_Verified" "Presequence_translocase-associated_motor_subunit,_required_for_stable_complex_formation_between_cochaperones_Pam16p_and_Pam18p,_promotes_association_of_Pam16p-Pam18p_with_the_presequence_translocase" YKR066C CCP1 None response_to_oxidative_stress cytochrome-c_peroxidase_activity mitochondrion* None None 11 566840 565755 YKR066C S000001774 "ORF,_Verified" "Mitochondrial_cytochrome-c_peroxidase;_degrades_reactive_oxygen_species_in_mitochondria,_involved_in_the_response_to_oxidative_stress" YKR068C BET3 None ER_to_Golgi_transport molecular_function_unknown Golgi_apparatus* None None 11 570551 569970 YKR068C S000001776 "ORF,_Verified" Hydrophilic_protein_that_acts_in_conjunction_with_SNARE_proteins_in_targeting_and_fusion_of_ER_to_Golgi_transport_vesicles;_component_of_the_TRAPP_(transport_protein_particle)_complex YKR070W None None biological_process_unknown molecular_function_unknown mitochondrion None None 11 573216 574274 YKR070W S000001778 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YKR072C SIS2 HAL3 G1/S_transition_of_mitotic_cell_cycle* phosphopantothenoylcysteine_decarboxylase_activity* cytoplasm* None None 11 577765 576077 YKR072C S000001780 "ORF,_Verified" Negative_regulatory_subunit_of_the_protein_phosphatase_1_Ppz1p;_involved_in_ion_homeostasis_and_cell_cycle_progression YKR074W None None biological_process_unknown molecular_function_unknown cytoplasm None None 11 578851 579318 YKR074W S000001782 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_epitope-tagged_protein_localizes_to_the_cytoplasm;_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation) YKR076W ECM4 GTO2 cell_wall_organization_and_biogenesis molecular_function_unknown cytoplasm None Up 11 581925 583037 YKR076W S000001784 "ORF,_Verified" Omega_class_glutathione_transferase;_not_essential;_similar_to_Ygr154cp;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm YKR077W MSA2 None biological_process_unknown molecular_function_unknown cytoplasm* G1 None 11 583295 584386 YKR077W S000001785 "ORF,_Verified" "Putative_transcriptional_activator,_that_interacts_with_G1-specific_transcription_factor,_MBF_and_G1-specific_promoters;_ortholog_of_Msa2p,_an_MBF_and_SBF_activator_that_regulates_G1-specific_transcription_and_cell_cycle_initiation" YKR080W MTD1 None one-carbon_compound_metabolism* methylenetetrahydrofolate_dehydrogenase_(NAD+)_activity cytosol None None 11 590037 590999 YKR080W S000001788 "ORF,_Verified" "NAD-dependent_5,10-methylenetetrahydrafolate_dehydrogenase,_plays_a_catalytic_role_in_oxidation_of_cytoplasmic_one-carbon_units;_expression_is_regulated_by_Bas1p_and_Bas2p,_repressed_by_adenine,_and_may_be_induced_by_inositol_and_choline" YKR081C RPF2 None ribosomal_large_subunit_assembly_and_maintenance* rRNA_binding* nucleolus None Down 11 592182 591148 YKR081C S000001789 "ORF,_Verified" Essential_protein_involved_in_the_processing_of_pre-rRNA_and_the_assembly_of_the_60S_ribosomal_subunit;_interacts_with_ribosomal_protein_L11;_localizes_predominantly_to_the_nucleolus;_constituent_of_66S_pre-ribosomal_particles YKR082W NUP133 RAT3 mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 11 592467 595940 YKR082W S000001790 "ORF,_Verified" "Subunit_of_the_Nup84p_subcomplex_of_the_nuclear_pore_complex_(NPC),_localizes_to_both_sides_of_the_NPC,_required_to_establish_a_normal_nucleocytoplasmic_concentration_gradient_of_the_GTPase_Gsp1p" YKR088C TVP38 None biological_process_unknown molecular_function_unknown cytoplasm* None None 11 605060 604047 YKR088C S000001796 "ORF,_Verified" Integral_membrane_protein_localized_to_late_Golgi_vesicles_along_with_the_v-SNARE_Tlg2p;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_in_a_punctate_pattern YKR089C TGL4 STC1 triacylglycerol_mobilization triacylglycerol_lipase_activity lipid_particle None None 11 608007 605275 YKR089C S000001797 "ORF,_Verified" Triacylglycerol_lipase_involved_in_triacylglycerol_mobilization_and_degradation;_found_in_lipid_particles;_potential_Cdc28p_substrate YKR090W PXL1 None maintenance_of_cell_polarity_(sensu_Fungi) protein_binding cytoplasm* G1 None 11 608588 610708 YKR090W S000001798 "ORF,_Verified" "LIM_domain-containing_protein_that_localizes_to_sites_of_polarized_growth,_required_for_selection_and/or_maintenance_of_polarized_growth_sites,_may_modulate_signaling_by_the_GTPases_Cdc42p_and_Rho1p;_has_similarity_to_metazoan_paxillin" YKR093W PTR2 None peptide_transport peptide_transporter_activity plasma_membrane None None 11 615372 617177 YKR093W S000001801 "ORF,_Verified" "Integral_membrane_peptide_transporter,_mediates_transport_of_di-_and_tri-peptides;_conserved_protein_that_contains_12_transmembrane_domains;_PTR2_expression_is_regulated_by_the_N-end_rule_pathway_via_repression_by_Cup9p" YKR094C RPL40B UB12|CEP52B|UBI2 protein_biosynthesis* structural_constituent_of_ribosome* mitochondrion* None None 11 618392 617638 YKR094C S000001802 "ORF,_Verified" "Fusion_protein,_identical_to_Rpl40Ap,_that_is_cleaved_to_yield_ubiquitin_and_a_ribosomal_protein_of_the_large_(60S)_ribosomal_subunit_with_similarity_to_rat_L40;_ubiquitin_may_facilitate_assembly_of_the_ribosomal_protein_into_ribosomes" YKR095W MLP1 MPL1 mRNA_export_from_nucleus* ribonucleoprotein_binding nuclear_envelope* None None 11 619447 625074 YKR095W S000001803 "ORF,_Verified" "Myosin-like_protein_associated_with_the_nuclear_envelope,_connects_the_nuclear_pore_complex_with_the_nuclear_interior;_involved_with_Tel1p_in_telomere_length_control;_involved_with_Pml1p_and_Pml39p_in_nuclear_retention_of_unspliced_mRNAs" YKR096W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 11 626435 630022 YKR096W S000001804 "ORF,_Verified" "Protein_of_unknown_function_that_may_interact_with_ribosomes,_based_on_co-purification_experiments;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus_and_cytoplasm;_predicted_to_contain_a_PINc_(PilT_N_terminus)_domain" YKR097W PCK1 PPC1|JPM2 gluconeogenesis phosphoenolpyruvate_carboxykinase_(ATP)_activity cytosol None None 11 630790 632439 YKR097W S000001805 "ORF,_Verified" "Phosphoenolpyruvate_carboxykinase,_key_enzyme_in_gluconeogenesis,_catalyzes_early_reaction_in_carbohydrate_biosynthesis,_glucose_represses_transcription_and_accelerates_mRNA_degradation,_regulated_by_Mcm1p_and_Cat8p,_located_in_the_cytosol" YKR098C UBP11 None biological_process_unknown ubiquitin-specific_protease_activity cellular_component_unknown None None 11 634817 632664 YKR098C S000001806 "ORF,_Verified" Ubiquitin-specific_protease_that_cleaves_ubiquitin_from_ubiquitinated_proteins YKR101W SIR1 None chromatin_silencing_at_silent_mating-type_cassette* DNA_binding* chromatin_silencing_complex None None 11 640178 642142 YKR101W S000001809 "ORF,_Verified" "Protein_involved_in_repression_of_transcription_at_the_silent_mating-type_loci_HML_and_HMR;_recruitment_to_silent_chromatin_requires_interactions_with_Orc1p_and_with_Sir4p,_through_a_common_Sir1p_domain;_binds_to_centromeric_chromatin" YKR102W FLO10 None flocculation_(sensu_Saccharomyces) mannose_binding cell_wall_(sensu_Fungi) None None 11 645994 649503 YKR102W S000001810 "ORF,_Verified" "Lectin-like_protein_with_similarity_to_Flo1p,_thought_to_be_involved_in_flocculation" YKR104W None NFT1 transport "ATPase_activity,_coupled_to_transmembrane_movement_of_substances" membrane None None 11 656474 657394 YKR104W S000001812 "ORF,_Verified" Putative_transporter_of_the_multidrug_resistance-associated_protein_(MRP)_subfamily;_contains_a_stop_codon_in_S288C;_adjacent_ORFs_YKR103W_and_YKR104W_are_merged_in_different_strain_backgrounds YKR106W None None transport transporter_activity membrane None None 11 661080 662927 YKR106W S000001814 "ORF,_Uncharacterized" Protein_of_unconfirmed_function;_displays_a_topology_characteristic_of_the_Major_Facilitators_Superfamily_of_membrane_proteins;_coding_sequence_98%_identical_to_that_of_YCL073C YLL002W RTT109 REM50|KIM2 negative_regulation_of_DNA_transposition molecular_function_unknown nucleus G1 None 12 146290 147600 YLL002W S000003925 "ORF,_Verified" Histone_acetyltransferase_critical_for_cell_survival_in_the_presence_of_DNA_damage_during_S_phase;_acetylates_H3-K56_and_H3-K9;_involved_in_non-homologous_end_joining_and_in_regulation_of_Ty1_transposition;_interacts_physically_with_Vps75p YLL003W SFI1 None G2/M_transition_of_mitotic_cell_cycle* molecular_function_unknown half_bridge_of_spindle_pole_body None None 12 143200 146040 YLL003W S000003926 "ORF,_Verified" "Centrin_(Cdc31p)-binding_protein_required_for_spindle_pole_body_(SPB)_duplication,_localizes_to_the_half-bridge_of_the_SPB,_required_for_progression_through_G(2)-M_transition,_has_similarity_to_Xenopus_laevis_XCAP-C" YLL004W ORC3 None DNA_replication_initiation* DNA_replication_origin_binding pre-replicative_complex* None None 12 141072 142922 YLL004W S000003927 "ORF,_Verified" "Subunit_of_the_origin_recognition_complex,_which_directs_DNA_replication_by_binding_to_replication_origins_and_is_also_involved_in_transcriptional_silencing" YLL005C SPO75 None sporulation_(sensu_Fungi)* molecular_function_unknown cellular_component_unknown None None 12 140545 137939 YLL005C S000003928 "ORF,_Verified" "Meiosis-specific_protein_of_unknown_function,_required_for_spore_wall_formation_during_sporulation;_dispensable_for_both_nuclear_divisions_during_meiosis" YLL006W MMM1 YME6 mitochondrion_organization_and_biogenesis* molecular_function_unknown mitochondrial_outer_membrane None None 12 136585 137865 YLL006W S000003929 "ORF,_Verified" "Mitochondrial_outer_membrane_protein,_component_of_the_Mdm10-Mdm12-Mmm1_complex_involved_in_import_and_assembly_of_outer_membrane_beta-barrel_proteins" YLL007C None None biological_process_unknown molecular_function_unknown cytoplasm None None 12 136298 134301 YLL007C S000003930 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YLL007C_is_not_an_essential_gene YLL009C COX17 None cytochrome_c_oxidase_complex_assembly* thioredoxin_peroxidase_activity* cytosol* None None 12 131413 131204 YLL009C S000003932 "ORF,_Verified" Copper_metallochaperone_that_transfers_copper_to_Sco1p_and_Cox11p_for_eventual_delivery_to_cytochrome_c_oxidase YLL011W SOF1 None rRNA_modification* snoRNA_binding nucleolus* None None 12 127522 128991 YLL011W S000003934 "ORF,_Verified" Essential_protein_required_for_biogenesis_of_40S_(small)_ribosomal_subunit;_has_similarity_to_the_beta_subunit_of_trimeric_G-proteins_and_the_splicing_factor_Prp4p YLL012W YEH1 None sterol_metabolism sterol_esterase_activity integral_to_membrane* G1 None 12 125533 127254 YLL012W S000003935 "ORF,_Verified" "Steryl_ester_hydrolase,_one_of_three_gene_products_(Yeh1p,_Yeh2p,_Tgl1p)_responsible_for_steryl_ester_hydrolase_activity_and_involved_in_sterol_homeostasis;_localized_to_lipid_particle_membranes" YLL016W SDC25 None Ras_protein_signal_transduction Ras_guanyl-nucleotide_exchange_factor_activity cellular_component_unknown None None 12 112846 115992 YLL016W S000003939 "pseudogene,_None" Non-essential_Ras_guanine_nucleotide_exchange_factor_(GEF)_localized_to_the_membrane;_expressed_in_poor_nutrients_and_on_non-fermentable_carbon_sources;_homologous_to_CDC25;_contains_a_stop_codon_in_S288C;_full-length_gene_includes_YLL017W YLL018C DPS1 None protein_biosynthesis RNA_binding* cytoplasm None None 12 111574 109901 YLL018C S000003941 "ORF,_Verified" "Cytoplasmic_aspartyl-tRNA_synthetase,_homodimeric_enzyme_that_catalyzes_the_specific_aspartylation_of_tRNA(Asp);_class_II_aminoacyl_tRNA_synthetase;_binding_to_its_own_mRNA_may_confer_autoregulation" YLL018C-A COX19 None cytochrome_c_oxidase_complex_assembly* metal_ion_transporter_activity cytosol* None None 12 108971 108675 YLL018C-A S000007245 "ORF,_Verified" "Protein_required_for_cytochrome_c_oxidase_assembly,_located_in_the_cytosol_and_mitochondrial_intermembrane_space;_putative_copper_metallochaperone_that_delivers_copper_to_cytochrome_c_oxidase" YLL019C KNS1 L124 protein_amino_acid_phosphorylation protein_serine/threonine_kinase_activity* cellular_component_unknown None Up 12 107898 105685 YLL019C S000003942 "ORF,_Verified" "Nonessential_putative_protein_kinase_of_unknown_cellular_role;_member_of_the_LAMMER_family_of_protein_kinases,_which_are_serine/threonine_kinases_also_capable_of_phosphorylating_tyrosine_residues" YLL021W SPA2 PEA1|FUS6 actin_filament_organization* cytoskeletal_regulatory_protein_binding bud_neck* None None 12 100946 105346 YLL021W S000003944 "ORF,_Verified" "Component_of_the_polarisome,_which_functions_in_actin_cytoskeletal_organization_during_polarized_growth;_acts_as_a_scaffold_for_Mkk1p_and_Mpk1p_cell_wall_integrity_signaling_components;_potential_Cdc28p_substrate" YLL022C HIF1 None chromatin_silencing_at_telomere molecular_function_unknown nucleus* G1 None 12 100200 99043 YLL022C S000003945 "ORF,_Verified" "Non-essential_component_of_the_HAT-B_histone_acetyltransferase_complex_(Hat1p-Hat2p-Hif1p),_localized_to_the_nucleus;_has_a_role_in_telomeric_silencing" YLL023C None None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 12 98835 97996 YLL023C S000003946 "ORF,_Verified" "Protein_of_unknown_function;_highly_conserved_across_species_and_orthologous_to_human_TMEM33;_may_interact_with_ribosomes,_based_on_co-purification_experiments;_GFP-fusion_protein_localizes_to_the_endoplasmic_reticulum" YLL024C SSA2 YG102 protein_folding ATP_binding cytoplasm* None None 12 97484 95565 YLL024C S000003947 "ORF,_Verified" "ATP_binding_protein_involved_in_protein_folding_and_vacuolar_import_of_proteins;_member_of_heat_shock_protein_70_(HSP70)_family;_associated_with_the_chaperonin-containing_T-complex;_present_in_the_cytoplasm,_vacuolar_membrane_and_cell_wall" YLL026W HSP104 None response_to_stress* chaperone_binding* cytoplasm* None None 12 88622 91348 YLL026W S000003949 "ORF,_Verified" "Heat_shock_protein_that_cooperates_with_Ydj1p_(Hsp40)_and_Ssa1p_(Hsp70)_to_refold_and_reactivate_previously_denatured,_aggregated_proteins;_responsive_to_stresses_including:_heat,_ethanol,_and_sodium_arsenite;_involved_in_[PSI+]_propagation" YLL027W ISA1 None iron_ion_transport molecular_function_unknown mitochondrial_matrix None None 12 87402 88154 YLL027W S000003950 "ORF,_Verified" "Mitochondrial_matrix_protein_involved_in_biogenesis_of_the_iron-sulfur_(Fe/S)_cluster_of_Fe/S_proteins,_isa1_deletion_causes_loss_of_mitochondrial_DNA_and_respiratory_deficiency;_depletion_reduces_growth_on_nonfermentable_carbon_sources" YLL029W FRA1 RUP2 biological_process_unknown molecular_function_unknown cytoplasm None Up 12 81460 83709 YLL029W S000003952 "ORF,_Verified" "Protein_involved_in_negative_regulation_of_transcription_of_iron_regulon;_forms_an_iron_independent_complex_with_Fra2p,_Grx3p,_and_Grx4p;_cytosolic;_mutant_fails_to_repress_transcription_of_iron_regulon_and_is_defective_in_spore_formation" YLL031C GPI13 MPC1 GPI_anchor_biosynthesis "transferase_activity,_transferring_phosphorus-containing_groups" endoplasmic_reticulum None None 12 80204 77151 YLL031C S000003954 "ORF,_Verified" ER_membrane_localized_phosphoryltransferase_that_adds_phosphoethanolamine_onto_the_third_mannose_residue_of_the_glycosylphosphatidylinositol_(GPI)_anchor_precursor;_similar_to_human_PIG-O_protein YLL034C RIX7 None ribosomal_large_subunit_export_from_nucleus ATPase_activity* nucleus* None None 12 73145 70632 YLL034C S000003957 "ORF,_Verified" "Putative_ATPase_of_the_AAA_family,_required_for_export_of_pre-ribosomal_large_subunits_from_the_nucleus;_distributed_between_the_nucleolus,_nucleoplasm,_and_nuclear_periphery_depending_on_growth_conditions" YLL035W GRC3 None rRNA_processing molecular_function_unknown cellular_component_unknown None None 12 68579 70477 YLL035W S000003958 "ORF,_Verified" "Protein_of_unknown_function,_required_for_cell_growth_and_possibly_involved_in_rRNA_processing;_mRNA_is_cell_cycle_regulated" YLL036C PRP19 PSO4 "nuclear_mRNA_splicing,_via_spliceosome*" "RNA_splicing_factor_activity,_transesterification_mechanism" cytoplasm* None None 12 68255 66744 YLL036C S000003959 "ORF,_Verified" "Splicing_factor_associated_with_the_spliceosome;_contains_a_U-box,_a_motif_found_in_a_class_of_ubiquitin_ligases" YLL038C ENT4 None endocytosis* clathrin_binding actin_cortical_patch None Up 12 66517 65774 YLL038C S000003961 "ORF,_Verified" "Protein_of_unknown_function,_contains_an_N-terminal_epsin-like_domain" YLL039C UBI4 UB14|SCD2 response_to_stress* protein_tag* cytoplasm None Up 12 65206 64061 YLL039C S000003962 "ORF,_Verified" "Ubiquitin,_becomes_conjugated_to_proteins,_marking_them_for_selective_degradation_via_the_ubiquitin-26S_proteasome_system;_essential_for_the_cellular_stress_response;_encoded_as_a_polyubiquitin_precursor_comprised_of_5_head-to-tail_repeats" YLL040C VPS13 VPT2|SOI1 sporulation_(sensu_Fungi)* molecular_function_unknown mitochondrion* None None 12 63644 54210 YLL040C S000003963 "ORF,_Verified" "Protein_of_unknown_function;_heterooligomeric_or_homooligomeric_complex;_peripherally_associated_with_membranes;_homologous_to_human_COH1;_involved_in_sporulation,_vacuolar_protein_sorting_and_protein-Golgi_retention" YLL041C SDH2 ACN17 tricarboxylic_acid_cycle* succinate_dehydrogenase_(ubiquinone)_activity respiratory_chain_complex_II_(sensu_Eukaryota) None None 12 53930 53130 YLL041C S000003964 "ORF,_Verified" "Iron-sulfur_protein_subunit_of_succinate_dehydrogenase_(Sdh1p,_Sdh2p,_Sdh3p,_Sdh4p),_which_couples_the_oxidation_of_succinate_to_the_transfer_of_electrons_to_ubiquinone" YLL042C ATG10 APG10 protein_targeting_to_vacuole* APG12_conjugating_enzyme_activity cytoplasm None None 12 52589 52086 YLL042C S000003965 "ORF,_Verified" "Conserved_E2-like_conjugating_enzyme_that_mediates_formation_of_the_Atg12p-Atg5p_conjugate,_which_is_a_critical_step_in_autophagy" YLL043W FPS1 None transport* transporter_activity* cytoplasm* None None 12 49937 51946 YLL043W S000003966 "ORF,_Verified" "Plasma_membrane_channel,_member_of_major_intrinsic_protein_(MIP)_family;_involved_in_efflux_of_glycerol_and_in_uptake_of_acetic_acid_and_the_trivalent_metalloids_arsenite_and_antimonite;_phosphorylated_by_Hog1p_MAPK_under_acetate_stress" YLL045C RPL8B SCL41|KRB1 protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 12 48628 47858 YLL045C S000003968 "ORF,_Verified" "Ribosomal_protein_L4_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl8Ap_and_has_similarity_to_rat_L7a_ribosomal_protein;_mutation_results_in_decreased_amounts_of_free_60S_subunits" YLL048C YBT1 BAT1 bile_acid_transport "ATPase_activity,_coupled_to_transmembrane_movement_of_substances*" vacuole_(sensu_Fungi) None None 12 46264 41279 YLL048C S000003971 "ORF,_Verified" Transporter_of_the_ATP-binding_cassette_(ABC)_family_involved_in_bile_acid_transport;_similar_to_mammalian_bile_transporters YLL049W LDB18 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 40665 41204 YLL049W S000003972 "ORF,_Verified" Protein_of_unknown_function;_null_mutant_shows_a_reduced_affinity_for_the_alcian_blue_dye_suggesting_a_decreased_net_negative_charge_of_the_cell_surface YLL050C COF1 None actin_filament_organization* protein_binding actin_cortical_patch None None 12 40413 39803 YLL050C S000003973 "ORF,_Verified" "Cofilin,_promotes_actin_filament_depolarization_in_a_pH-dependent_manner;_binds_both_actin_monomers_and_filaments_and_severs_filaments;_thought_to_be_regulated_by_phosphorylation_at_SER4;_ubiquitous_and_essential_in_eukaryotes" YLL051C FRE6 None biological_process_unknown ferric-chelate_reductase_activity vacuole_(sensu_Fungi) None None 12 39470 37332 YLL051C S000003974 "ORF,_Verified" Putative_ferric_reductase_with_similarity_to_Fre2p;_expression_induced_by_low_iron_levels YLL053C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 35960 35502 YLL053C S000003976 "ORF,_Uncharacterized" Putative_protein;_in_the_Sigma_1278B_strain_background_YLL053C_is_contiguous_with_AQY2_which_encodes_an_aquaporin YLL055W YCT1 None biological_process_unknown ion_transporter_activity endoplasmic_reticulum None None 12 30109 31704 YLL055W S000003978 "ORF,_Verified" High-affinity_cysteine-specific_transporter_with_similarity_to_the_Dal5p_family_of_transporters;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_endoplasmic_reticulum;_YCT1_is_not_an_essential_gene YLL056C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 28305 27409 YLL056C S000003979 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_transcription_is_activated_by_paralogous_transcription_factors_Yrm1p_and_Yrr1p_along_with_genes_involved_in_pleiotropic_drug_resistance_(PDR)_phenomenon;_YLL056C_is_not_an_essential_gene" YLL058W None None sulfur_metabolism cystathionine_gamma-synthase_activity cellular_component_unknown None Up 12 23569 25296 YLL058W S000003981 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function_with_similarity_to_Str2p,_which_is_a_cystathionine_gamma-synthase_important_in_sulfur_metabolism;_YLL058W_is_not_an_essential_gene" YLL061W MMP1 None S-methylmethionine_transport S-methylmethionine_transporter_activity plasma_membrane S None 12 17956 19707 YLL061W S000003984 "ORF,_Verified" "High-affinity_S-methylmethionine_permease,_required_for_utilization_of_S-methylmethionine_as_a_sulfur_source;_has_similarity_to_S-adenosylmethionine_permease_Sam3p" YLL064C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 13445 13083 YLL064C S000003987 "ORF,_Uncharacterized" Hypothetical_protein YLL066C None None biological_process_unknown helicase_activity cellular_component_unknown G1 None 12 9836 6120 YLL066C S000003989 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_helicases;_YLL066C_is_not_an_essential_gene YLL067C None None biological_process_unknown helicase_activity cellular_component_unknown G1 None 12 4301 585 YLL067C S000003990 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_helicases YLR003C CMS1 None regulation_of_DNA_replication molecular_function_unknown nucleus None None 12 157729 156854 YLR003C S000003993 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_that_may_participate_in_DNA_replication;_green_fluorescent_protein_(GFP)-fusion_protein_is_localized_to_the_nucleus;_YLR003C_is_not_an_essential_gene YLR006C SSK1 None osmosensory_signaling_pathway_via_two-component_system* enzyme_activator_activity* cytoplasm None None 12 163892 161754 YLR006C S000003996 "ORF,_Verified" "Cytoplasmic_response_regulator,_part_of_a_two-component_signal_transducer_that_mediates_osmosensing_via_a_phosphorelay_mechanism;_dephosphorylated_form_is_degraded_by_the_ubiquitin-proteasome_system;_potential_Cdc28p_substrate" YLR007W NSE1 None DNA_repair* molecular_function_unknown nucleus* None None 12 164391 165401 YLR007W S000003997 "ORF,_Verified" Essential_subunit_of_the_Mms21-Smc5-Smc6_complex;_nuclear_protein_required_for_DNA_repair_and_growth;_has_a_nonstructural_role_in_the_maintenance_of_chromosomes YLR010C TEN1 None telomere_capping molecular_function_unknown nuclear_telomere_cap_complex None None 12 167801 167319 YLR010C S000004000 "ORF,_Verified" Protein_that_regulates_telomeric_length;_protects_telomeric_ends_in_a_complex_with_Cdc13p_and_Stn1p YLR012C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 170280 169981 YLR012C S000004002 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YLR012C_is_not_an_essential_gene YLR014C PPR1 None "regulation_of_transcription,_DNA-dependent*" transcription_factor_activity nucleus None None 12 174981 172267 YLR014C S000004004 "ORF,_Verified" "Zinc_finger_transcription_factor_containing_a_Zn(2)-Cys(6)_binuclear_cluster_domain,_positively_regulates_transcription_of_genes_involved_in_uracil_biosynthesis;_activity_may_be_modulated_by_interaction_with_Tup1p" YLR015W BRE2 CPS60 chromatin_silencing_at_telomere* transcription_regulator_activity* COMPASS_complex None None 12 175226 176743 YLR015W S000004005 "ORF,_Verified" "Subunit_of_the_COMPASS_(Set1C)_complex,_which_methylates_histone_H3_on_lysine_4_and_is_required_in_transcriptional_silencing_near_telomeres;_involved_in_telomere_maintenance;_similar_to_trithorax-group_protein_ASH2L" YLR016C PML1 None "nuclear_mRNA_splicing,_via_spliceosome*" molecular_function_unknown cytoplasm* None None 12 177415 176801 YLR016C S000004006 "ORF,_Verified" "Subunit_of_the_RES_complex,_which_is_required_for_nuclear_retention_of_unspliced_pre-mRNAs;_acts_in_the_same_pathway_as_Pml39p_and_Mlp1p" YLR018C POM34 None nucleocytoplasmic_transport molecular_function_unknown nuclear_pore None None 12 179605 178706 YLR018C S000004008 "ORF,_Verified" Integral_membrane_protein_of_the_nuclear_pore;_has_an_important_role_in_maintaining_the_architecture_of_the_pore_complex YLR019W PSR2 None response_to_stress phosphoprotein_phosphatase_activity plasma_membrane None None 12 180287 181480 YLR019W S000004009 "ORF,_Verified" "Functionally_redundant_Psr1p_homolog,_a_plasma_membrane_phosphatase_involved_in_the_general_stress_response;_required_with_Psr1p_and_Whi2p_for_full_activation_of_STRE-mediated_gene_expression,_possibly_through_dephosphorylation_of_Msn2p" YLR020C YEH2 None cell_wall_mannoprotein_biosynthesis* sterol_esterase_activity plasma_membrane* None None 12 183404 181788 YLR020C S000004010 "ORF,_Verified" "Steryl_ester_hydrolase,_catalyzes_steryl_ester_hydrolysis_at_the_plasma_membrane;_involved_in_sterol_metabolism" YLR021W IRC25 DMP2|PBA3|POC3 biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 183622 184161 YLR021W S000004011 "ORF,_Verified" Component_of_a_heterodimeric_Poc4p-Irc25p_chaperone_involved_in_assembly_of_alpha_subunits_into_the_20S_proteasome;_may_regulate_formation_of_proteasome_isoforms_with_alternative_subunits_under_different_conditions YLR022C SDO1 None 35S_primary_transcript_processing* molecular_function_unknown cytoplasm* None None 12 184925 184173 YLR022C S000004012 "ORF,_Verified" Essential_protein_involved_in_60S_ribosome_maturation;_ortholog_of_the_human_protein_(SBDS)_responsible_for_autosomal_recessive_Shwachman-Bodian-Diamond_Syndrome;_highly_conserved_across_archae_and_eukaryotes YLR023C IZH3 None lipid_metabolism* metal_ion_binding endoplasmic_reticulum* None None 12 187128 185497 YLR023C S000004013 "ORF,_Verified" "Membrane_protein_involved_in_zinc_metabolism,_member_of_the_four-protein_IZH_family,_expression_induced_by_zinc_deficiency;_deletion_reduces_sensitivity_to_elevated_zinc_and_shortens_lag_phase,_overexpression_reduces_Zap1p_activity" YLR024C UBR2 None protein_monoubiquitination* ubiquitin-protein_ligase_activity cytoplasm None None 12 193282 187664 YLR024C S000004014 "ORF,_Verified" Cytoplasmic_ubiquitin-protein_ligase_(E3);_required_for_ubiquitylation_of_Rpn4p;_mediates_formation_of_a_Mub1p-Ubr2p-Rad6p_complex YLR025W SNF7 RNS4|VPS32|DID1 late_endosome_to_vacuole_transport* molecular_function_unknown cytoplasm* None None 12 194453 195175 YLR025W S000004015 "ORF,_Verified" One_of_four_subunits_of_the_endosomal_sorting_complex_required_for_transport_III_(ESCRT-III);_involved_in_the_sorting_of_transmembrane_proteins_into_the_multivesicular_body_(MVB)_pathway;_recruited_from_the_cytoplasm_to_endosomal_membranes YLR026C SED5 None ER_to_Golgi_transport* t-SNARE_activity Golgi_cis-face None None 12 196473 195451 YLR026C S000004016 "ORF,_Verified" "cis-Golgi_t-SNARE_syntaxin_required_for_vesicular_transport_between_the_ER_and_the_Golgi_complex,_binds_at_least_9_SNARE_proteins" YLR027C AAT2 ASP5 nitrogen_compound_metabolism* aspartate_transaminase_activity cytoplasm* None None 12 198086 196830 YLR027C S000004017 "ORF,_Verified" "Cytosolic_aspartate_aminotransferase,_involved_in_nitrogen_metabolism;_localizes_to_peroxisomes_in_oleate-grown_cells" YLR028C ADE16 None aerobic_respiration* IMP_cyclohydrolase_activity* cytosol None None 12 201316 199541 YLR028C S000004018 "ORF,_Verified" "Enzyme_of_'de_novo'_purine_biosynthesis_containing_both_5-aminoimidazole-4-carboxamide_ribonucleotide_transformylase_and_inosine_monophosphate_cyclohydrolase_activities,_isozyme_of_Ade17p;_ade16_ade17_mutants_require_adenine_and_histidine" YLR029C RPL15A RPL10A protein_biosynthesis structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 12 202591 201977 YLR029C S000004019 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl15Bp_and_has_similarity_to_rat_L15_ribosomal_protein;_binds_to_5.8_S_rRNA" YLR030W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 203291 204082 YLR030W S000004020 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YLR031W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 204226 204786 YLR031W S000004021 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YLR032W RAD5 SNM2|REV2 DNA_repair* ATPase_activity* nuclear_chromatin G1 None 12 204992 208501 YLR032W S000004022 "ORF,_Verified" DNA_helicase_proposed_to_promote_replication_fork_regression_during_postreplication_repair_by_template_switching;_contains_RING_finger_domain YLR033W RSC58 None chromatin_remodeling molecular_function_unknown RSC_complex None None 12 208762 210270 YLR033W S000004023 "ORF,_Verified" "Component_of_the_RSC_chromatin_remodeling_complex;_RSC_functions_in_transcriptional_regulation_and_elongation,_chromosome_stability,_and_establishing_sister_chromatid_cohesion;_involved_in_telomere_maintenance" YLR034C SMF3 None intracellular_sequestering_of_iron_ion iron_ion_transporter_activity vacuolar_membrane_(sensu_Fungi) G2/M None 12 211934 210513 YLR034C S000004024 "ORF,_Verified" Putative_divalent_metal_ion_transporter_involved_in_iron_homeostasis;_transcriptionally_regulated_by_metal_ions;_member_of_the_Nramp_family_of_metal_transport_proteins YLR035C MLH2 None DNA_repair molecular_function_unknown nucleus None None 12 214457 212370 YLR035C S000004025 "ORF,_Verified" Protein_involved_in_the_mismatch_repair_of_certain_frameshift_intermediates_and_involved_in_meiotic_recombination;_forms_a_complex_with_Mlh1p YLR035C-A None None None None None None None 12 218908 215441 YLR035C-A S000007225 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_YLR035C-A_is_part_of_a_mutant_retrotransposon" YLR036C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 222133 221522 YLR036C S000004026 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_predicted_to_have_transmembrane_domains;_interacts_with_HSP90_by_yeast_two-hybrid_analysis;_YLR036C_is_not_an_essential_protein YLR039C RIC1 None intracellular_protein_transport guanyl-nucleotide_exchange_factor_activity nucleus* None None 12 228597 225427 YLR039C S000004029 "ORF,_Verified" Protein_involved_in_retrograde_transport_to_the_cis-Golgi_network;_forms_heterodimer_with_Rgp1p_that_acts_as_a_GTP_exchange_factor_for_Ypt6p;_involved_in_transcription_of_rRNA_and_ribosomal_protein_genes YLR040C None None biological_process_unknown molecular_function_unknown cell_wall_(sensu_Fungi) M/G1 None 12 229583 228909 YLR040C S000004030 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_localizes_to_the_cell_wall;_predicted_to_be_a_GPI-attached_protein;_upregulated_by_Mcm1p-Alpha1p_transcription_factor;_partially_overlaps_the_dubious_ORF_YLR041W;_YLR040C_is_not_essential YLR042C None None biological_process_unknown molecular_function_unknown cell_wall_(sensu_Fungi) None None 12 230452 229967 YLR042C S000004032 "ORF,_Uncharacterized" Protein_of_unknown_function;_localizes_to_the_cytoplasm;_YLL042C_is_not_an_essential_gene YLR043C TRX1 LMA1 ER_to_Golgi_transport* thiol-disulfide_exchange_intermediate_activity cytosol* None None 12 232014 231703 YLR043C S000004033 "ORF,_Verified" "Cytoplasmic_thioredoxin_isoenzyme_of_the_thioredoxin_system_which_protects_cells_against_oxidative_and_reductive_stress,_forms_LMA1_complex_with_Pbi2p,_acts_as_a_cofactor_for_Tsa1p,_required_for_ER-Golgi_transport_and_vacuole_inheritance" YLR044C PDC1 None pyruvate_metabolism* pyruvate_decarboxylase_activity cytoplasm* None None 12 234082 232391 YLR044C S000004034 "ORF,_Verified" "Major_of_three_pyruvate_decarboxylase_isozymes,_key_enzyme_in_alcoholic_fermentation,_decarboxylates_pyruvate_to_acetaldehyde;_subject_to_glucose-,_ethanol-,_and_autoregulation;_involved_in_amino_acid_catabolism" YLR045C STU2 None mitotic_spindle_organization_and_biogenesis_in_nucleus* structural_constituent_of_cytoskeleton* spindle_pole_body* S None 12 237704 235038 YLR045C S000004035 "ORF,_Verified" Microtubule-associated_protein_(MAP)_of_the_XMAP215/Dis1_family;_regulates_microtubule_dynamics_during_spindle_orientation_and_metaphase_chromosome_alignment;_interacts_with_spindle_pole_body_component_Spc72p YLR046C None RLA1 biological_process_unknown molecular_function_unknown integral_to_membrane None Up 12 238814 238002 YLR046C S000004036 "ORF,_Uncharacterized" "Putative_membrane_protein,_transcription_is_activated_by_paralogous_transcription_factors_Yrm1p_and_Yrr1p_along_with_genes_involved_in_multidrug_resistance" YLR047C FRE8 None metal_ion_homeostasis "oxidoreductase_activity,_oxidizing_metal_ions" membrane None None 12 241408 239348 YLR047C S000004037 "ORF,_Verified" "Protein_with_sequence_similarity_to_iron/copper_reductases,_involved_in_iron_homeostasis;_deletion_mutant_has_iron_deficiency/accumulation_growth_defects;_expression_increased_in_the_absence_of_copper-responsive_transcription_factor_Mac1p" YLR048W RPS0B YST2|NAB1B protein_biosynthesis* structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None Down 12 242233 243350 YLR048W S000004038 "ORF,_Verified" "Protein_component_of_the_small_(40S)_ribosomal_subunit,_nearly_identical_to_Rps0Ap;_required_for_maturation_of_18S_rRNA_along_with_Rps0Ap;_deletion_of_either_RPS0_gene_reduces_growth_rate,_deletion_of_both_genes_is_lethal" YLR049C None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 12 245173 243887 YLR049C S000004039 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YLR050C None None biological_process_unknown molecular_function_unknown endoplasmic_reticulum G1 None 12 246073 245588 YLR050C S000004040 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_endoplasmic_reticulum;_YLR050C_is_not_an_essential_gene YLR051C FCF2 None biological_process_unknown molecular_function_unknown nucleus* None None 12 246978 246325 YLR051C S000004041 "ORF,_Verified" Essential_nucleolar_protein_involved_in_the_early_steps_of_35S_rRNA_processing;_interacts_with_Faf1p;_member_of_a_transcriptionally_co-regulated_set_of_genes_called_the_RRB_regulon YLR052W IES3 None chromatin_remodeling molecular_function_unknown nucleus* None None 12 247202 247954 YLR052W S000004042 "ORF,_Verified" Subunit_of_the_INO80_chromatin_remodeling_complex YLR053C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 248427 248101 YLR053C S000004043 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YLR054C OSW2 None spore_wall_assembly_(sensu_Fungi) molecular_function_unknown cytoplasm* None None 12 250979 248718 YLR054C S000004044 "ORF,_Uncharacterized" Protein_of_unknown_function_proposed_to_be_involved_in_the_assembly_of_the_spore_wall YLR055C SPT8 None histone_acetylation* transcription_cofactor_activity nucleus* None None 12 253081 251273 YLR055C S000004045 "ORF,_Verified" "Subunit_of_the_SAGA_transcriptional_regulatory_complex_but_not_present_in_SAGA-like_complex_SLIK/SALSA,_required_for_SAGA-mediated_inhibition_at_some_promoters" YLR056W ERG3 PSO6|SYR1 ergosterol_biosynthesis C-5_sterol_desaturase_activity endoplasmic_reticulum S/G2 Down 12 253862 254959 YLR056W S000004046 "ORF,_Verified" "C-5_sterol_desaturase,_catalyzes_the_introduction_of_a_C-5(6)_double_bond_into_episterol,_a_precursor_in_ergosterol_biosynthesis;_mutants_are_viable,_but_cannot_grow_on_non-fermentable_carbon_sources" YLR057W None None biological_process_unknown molecular_function_unknown cellular_component_unknown G2/M None 12 255307 257856 YLR057W S000004047 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YLR050C_is_not_an_essential_gene YLR058C SHM2 SHMT2 one-carbon_compound_metabolism glycine_hydroxymethyltransferase_activity cytoplasm S/G2 None 12 259402 257993 YLR058C S000004048 "ORF,_Verified" "Cytosolic_serine_hydroxymethyltransferase,_converts_serine_to_glycine_plus_5,10_methylenetetrahydrofolate;_major_isoform_involved_in_generating_precursors_for_purine,_pyrimidine,_amino_acid,_and_lipid_biosynthesis" YLR059C REX2 YNT20 RNA_processing 3'-5'_exonuclease_activity mitochondrion None None 12 260548 259739 YLR059C S000004049 "ORF,_Verified" "3'-5'_RNA_exonuclease;_involved_in_3'-end_processing_of_U4_and_U5_snRNAs,_5S_and_5.8S_rRNAs,_and_RNase_P_and_RNase_MRP_RNA;_localized_to_mitochondria_and_null_suppresses_escape_of_mtDNA_to_nucleus_in_yme1_yme2_mutants;_RNase_D_exonuclease" YLR061W RPL22A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 12 263195 263949 YLR061W S000004051 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_Rpl22Bp_and_to_rat_L22_ribosomal_protein" YLR063W None None biological_process_unknown molecular_function_unknown cytoplasm None None 12 264158 265255 YLR063W S000004053 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YLR063W_is_not_an_essential_gene YLR065C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 266919 266374 YLR065C S000004055 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YLR065C_is_not_an_essential_gene YLR066W SPC3 None signal_peptide_processing signal_peptidase_activity signal_peptidase_complex None None 12 267170 267724 YLR066W S000004056 "ORF,_Verified" "Subunit_of_signal_peptidase_complex_(Spc1p,_Spc2p,_Spc3p,_Sec11p),_which_catalyzes_cleavage_of_N-terminal_signal_sequences_of_proteins_targeted_to_the_secretory_pathway;_homologous_to_mammalian_SPC22/23" YLR067C PET309 None protein_biosynthesis* translation_regulator_activity integral_to_membrane* None None 12 270711 267814 YLR067C S000004057 "ORF,_Verified" "Specific_translational_activator_for_the_COX1_mRNA,_also_influences_stability_of_intron-containing_COX1_primary_transcripts;_localizes_to_the_mitochondrial_inner_membrane;_contains_seven_pentatricopeptide_repeats_(PPRs)" YLR069C MEF1 None translational_elongation translation_elongation_factor_activity mitochondrion None None 12 273916 271631 YLR069C S000004059 "ORF,_Verified" Mitochondrial_elongation_factor_involved_in_translational_elongation YLR071C RGR1 MED14 transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_mediator_activity mediator_complex None None 12 278627 275379 YLR071C S000004061 "ORF,_Verified" "Subunit_of_the_RNA_polymerase_II_mediator_complex;_associates_with_core_polymerase_subunits_to_form_the_RNA_polymerase_II_holoenzyme;_required_for_glucose_repression,_HO_repression,_RME1_repression_and_sporulation" YLR073C None None biological_process_unknown molecular_function_unknown endosome None None 12 281622 281020 YLR073C S000004063 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_endosomes;_YLR073C_is_not_an_esssential_gene YLR074C BUD20 None bud_site_selection molecular_function_unknown nucleus None None 12 282457 281957 YLR074C S000004064 "ORF,_Verified" Protein_involved_in_bud-site_selection;_diploid_mutants_display_a_random_budding_pattern_instead_of_the_wild-type_bipolar_pattern YLR075W RPL10 QSR1|GRC5 protein_biosynthesis* structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 12 282928 283593 YLR075W S000004065 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_responsible_for_joining_the_40S_and_60S_subunits;_regulates_translation_initiation;_has_similarity_to_rat_L10_ribosomal_protein_and_to_members_of_the_QM_gene_family" YLR077W None None biological_process_unknown molecular_function_unknown mitochondrion None None 12 283873 285624 YLR077W S000004067 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YLR078C BOS1 SEC32 ER_to_Golgi_transport v-SNARE_activity endoplasmic_reticulum_membrane None None 12 286560 285737 YLR078C S000004068 "ORF,_Verified" "v-SNARE_(vesicle_specific_SNAP_receptor),_localized_to_the_endoplasmic_reticulum_membrane_and_necessary_for_vesicular_transport_from_the_ER_to_the_Golgi" YLR079W SIC1 SDB25 G1/S_transition_of_mitotic_cell_cycle* protein_binding* cytoplasm* M/G1 None 12 286821 287675 YLR079W S000004069 "ORF,_Verified" "Inhibitor_of_Cdc28-Clb_kinase_complexes_that_controls_G1/S_phase_transition,_preventing_premature_S_phase_and_ensuring_genomic_integrity;_phosphorylation_targets_Sic1p_for_SCF(CDC4)-dependent_turnover;_functional_homolog_of_mammalian_Kip1" YLR080W EMP46 None ER_to_Golgi_transport molecular_function_unknown COPII-coated_vesicle* None Up 12 287917 289251 YLR080W S000004070 "ORF,_Verified" "Integral_membrane_component_of_endoplasmic_reticulum-derived_COPII-coated_vesicles,_which_function_in_ER_to_Golgi_transport" YLR081W GAL2 None galactose_metabolism* glucose_transporter_activity* plasma_membrane None None 12 290213 291937 YLR081W S000004071 "ORF,_Verified" "Galactose_permease,_required_for_utilization_of_galactose;_also_able_to_transport_glucose" YLR082C SRL2 None "nucleobase,_nucleoside,_nucleotide_and_nucleic_acid_metabolism" molecular_function_unknown cytoplasm* None None 12 293573 292395 YLR082C S000004072 "ORF,_Verified" Protein_of_unknown_function;_overexpression_suppresses_the_lethality_caused_by_a_rad53_null_mutation YLR083C EMP70 TMN1|p24a transport transporter_activity membrane_fraction* None None 12 296095 294092 YLR083C S000004073 "ORF,_Verified" Protein_with_a_role_in_cellular_adhesion_and_filamentous_growth;_similar_to_Tmn2p_and_Tmn3p;_member_of_Transmembrane_Nine_family_of_proteins_with_9_transmembrane_segments;_24kDa_cleavage_product_found_in_endosome-enriched_membrane_fractions YLR084C RAX2 None bud_site_selection molecular_function_unknown mitochondrion* G2/M None 12 300252 296590 YLR084C S000004074 "ORF,_Verified" N-glycosylated_protein_involved_in_the_maintenance_of_bud_site_selection_during_bipolar_budding;_localization_requires_Rax1p YLR085C ARP6 None protein_targeting_to_vacuole* molecular_function_unknown cytoplasm* None None 12 301990 300674 YLR085C S000004075 "ORF,_Verified" "Actin-related_protein_that_binds_nucleosomes;_a_component_of_the_SWR1_complex,_which_exchanges_histone_variant_H2AZ_(Htz1p)_for_chromatin-bound_histone_H2A" YLR086W SMC4 None mitotic_sister_chromatid_segregation* ATPase_activity* nuclear_condensin_complex None None 12 302244 306500 YLR086W S000004076 "ORF,_Verified" "Subunit_of_the_condensin_complex,_which_reorganizes_chromosomes_during_cell_division,_forms_a_stable_complex_with_Smc2p_that_has_ATP-hydrolyzing_and_DNA-binding_activity_and_promotes_knotting_of_circular_DNA;_potential_Cdc28p_substrate" YLR087C CSF1 None fermentation molecular_function_unknown mitochondrion None None 12 315732 306856 YLR087C S000004077 "ORF,_Verified" "Protein_required_for_fermentation_at_low_temperature;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YLR088W GAA1 END2 attachment_of_GPI_anchor_to_protein GPI-anchor_transamidase_activity GPI-anchor_transamidase_complex None None 12 316108 317952 YLR088W S000004078 "ORF,_Verified" "Subunit_of_the_GPI_(glycosylphosphatidylinositol):protein_transamidase_complex,_removes_the_GPI-anchoring_signal_and_attaches_GPI_to_proteins_in_the_ER" YLR089C ALT1 None biological_process_unknown transaminase_activity mitochondrion None None 12 320016 318238 YLR089C S000004079 "ORF,_Uncharacterized" "Putative_alanine_transaminase_(glutamic_pyruvic_transaminase);_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YLR091W None None biological_process_unknown molecular_function_unknown mitochondrion None None 12 322298 323179 YLR091W S000004081 "ORF,_Uncharacterized" "Protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_YLR091W_is_not_an_esssential_gene" YLR092W SUL2 None sulfate_transport sulfate_transporter_activity plasma_membrane None None 12 323545 326226 YLR092W S000004082 "ORF,_Verified" "High_affinity_sulfate_permease;_sulfate_uptake_is_mediated_by_specific_sulfate_transporters_Sul1p_and_Sul2p,_which_control_the_concentration_of_endogenous_activated_sulfate_intermediates" YLR093C NYV1 MAM2 vesicle_fusion v-SNARE_activity vacuolar_membrane None None 12 327416 326514 YLR093C S000004083 "ORF,_Verified" v-SNARE_component_of_the_vacuolar_SNARE_complex_involved_in_vesicle_fusion;_inhibits_ATP-dependent_Ca(2+)_transport_activity_of_Pmc1p_in_the_vacuolar_membrane YLR095C IOC2 None chromatin_remodeling protein_binding ISW1_complex G2/M None 12 332116 329678 YLR095C S000004085 "ORF,_Verified" "Member_of_a_complex_(Isw1b)_with_Isw1p_and_Ioc4p_that_exhibits_nucleosome-stimulated_ATPase_activity_and_acts_within_coding_regions_to_coordinate_transcription_elongation_with_termination_and_processing,_contains_a_PHD_finger_motif" YLR096W KIN2 None exocytosis protein_kinase_activity plasma_membrane* None None 12 332591 336034 YLR096W S000004086 "ORF,_Verified" Serine/threonine_protein_kinase_involved_in_regulation_of_exocytosis;_localizes_to_the_cytoplasmic_face_of_the_plasma_membrane;_closely_related_to_Kin1p YLR097C HRT3 None ubiquitin-dependent_protein_catabolism ubiquitin-protein_ligase_activity nuclear_ubiquitin_ligase_complex None None 12 337266 336232 YLR097C S000004087 "ORF,_Verified" "Putative_SCF-ubiquitin_ligase_F-box_protein,_based_on_both_genetic_and_physical_interactions_and_sequence_similarity;_identified_in_association_with_Cdc53p,_Skp1p_and_Ubi4_in_large_and_small-scale_studies" YLR098C CHA4 SIL3|SIL2 "regulation_of_transcription,_DNA-dependent*" transcription_factor_activity nucleus G2/M None 12 339474 337528 YLR098C S000004088 "ORF,_Verified" "DNA_binding_transcriptional_activator,_mediates_serine/threonine_activation_of_the_catabolic_L-serine_(L-threonine)_deaminase_(CHA1);_Zinc-finger_protein_with_Zn[2]-Cys[6]_fungal-type_binuclear_cluster_domain" YLR099C ICT1 None biological_process_unknown molecular_function_unknown cellular_component_unknown S/G2 None 12 340929 339745 YLR099C S000004089 "ORF,_Verified" "Lysophosphatidic_acid_acyltransferase,_responsible_for_enhanced_phospholipid_synthesis_during_organic_solvent_stress;_null_displays_increased_sensitivity_to_Calcofluor_white;_highly_expressed_during_organic_solvent_stress" YLR100W ERG27 None ergosterol_biosynthesis 3-keto_sterol_reductase_activity endoplasmic_reticulum* G2/M None 12 341811 342854 YLR100W S000004090 "ORF,_Verified" "3-keto_sterol_reductase,_catalyzes_the_last_of_three_steps_required_to_remove_two_C-4_methyl_groups_from_an_intermediate_in_ergosterol_biosynthesis;_mutants_are_sterol_auxotrophs" YLR102C APC9 None mitotic_sister_chromatid_segregation* protein_binding* anaphase-promoting_complex None None 12 343768 342971 YLR102C S000004092 "ORF,_Verified" "Subunit_of_the_Anaphase-Promoting_Complex/Cyclosome_(APC/C),_which_is_a_ubiquitin-protein_ligase_required_for_degradation_of_anaphase_inhibitors,_including_mitotic_cyclins,_during_the_metaphase/anaphase_transition" YLR103C CDC45 SLD4 DNA_replication_initiation* DNA_binding pre-replicative_complex* G1 None 12 345942 343990 YLR103C S000004093 "ORF,_Verified" "DNA_replication_initiation_factor;_recruited_to_MCM_pre-RC_complexes_at_replication_origins;_promotes_release_of_MCM_from_Mcm10p,_recruits_elongation_machinery;_mutants_in_human_homolog_may_cause_velocardiofacial_and_DiGeorge_syndromes" YLR104W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 346586 346981 YLR104W S000004094 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_mutant_is_deficient_in_amounts_of_cell_wall_mannosylphosphate YLR105C SEN2 None tRNA_splicing tRNA-intron_endonuclease_activity mitochondrial_outer_membrane* None None 12 348181 347048 YLR105C S000004095 "ORF,_Verified" "Subunit_of_the_tRNA_splicing_endonuclease,_which_is_composed_of_Sen2p,_Sen15p,_Sen34p,_and_Sen54p;_Sen2p_contains_the_active_site_for_tRNA_5'_splice_site_cleavage_and_has_similarity_to_Sen34p_and_to_Archaeal_tRNA_splicing_endonuclease" YLR106C MDN1 REA1 rRNA_processing* ATPase_activity nucleus* None None 12 363739 349007 YLR106C S000004096 "ORF,_Verified" "Huge_dynein-related_AAA-type_ATPase_(midasin),_forms_extended_pre-60S_particle_with_the_Rix1_complex_(Rix1p-Ipi1p-Ipi3p),_may_mediate_ATP-dependent_remodeling_of_60S_subunits_and_subsequent_export_from_nucleoplasm_to_cytoplasm" YLR107W REX3 None RNA_processing 3'-5'_exonuclease_activity cytoplasm* None None 12 364117 365331 YLR107W S000004097 "ORF,_Verified" RNA_exonuclease;_required_for_maturation_of_the_RNA_component_of_RNase_MRP;_functions_redundantly_with_Rnh70p_and_Rex2p_in_processing_of_U5_snRNA_and_RNase_P_RNA;_member_of_RNase_D_family_of_exonucleases YLR108C None None biological_process_unknown molecular_function_unknown nucleus None Up 12 368125 366668 YLR108C S000004098 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus;_YLR108C_is_not_an_esssential_gene YLR109W AHP1 None regulation_of_cell_redox_homeostasis* thioredoxin_peroxidase_activity cytoplasm None None 12 368782 369312 YLR109W S000004099 "ORF,_Verified" "Thiol-specific_peroxiredoxin,_reduces_hydroperoxides_to_protect_against_oxidative_damage;_function_in_vivo_requires_covalent_conjugation_to_Urm1p" YLR110C CCW12 None cell_wall_organization_and_biogenesis* molecular_function_unknown cell_wall_(sensu_Fungi) None None 12 370099 369698 YLR110C S000004100 "ORF,_Verified" "Cell_wall_mannoprotein,_mutants_are_defective_in_mating_and_agglutination,_expression_is_downregulated_by_alpha-factor" YLR113W HOG1 SSK3 protein_amino_acid_phosphorylation* MAP_kinase_activity cytoplasm* None None 12 371621 372928 YLR113W S000004103 "ORF,_Verified" Mitogen-activated_protein_kinase_involved_in_osmoregulation_via_three_independent_osmosensors;_mediates_the_recruitment_and_activation_of_RNA_Pol_II_at_Hot1p-dependent_promoters;_localization_regulated_by_Ptp2p_and_Ptp3p YLR114C AVL9 None biological_process_unknown molecular_function_unknown cytoplasm None None 12 377239 374945 YLR114C S000004104 "ORF,_Verified" Conserved_protein_involved_in_exocytic_transport_from_the_Golgi;_mutation_is_synthetically_lethal_with_apl2_vps1_double_mutation;_member_of_a_protein_superfamily_with_orthologs_in_diverse_organisms YLR115W CFT2 YDH1 mRNA_polyadenylylation* RNA_binding mRNA_cleavage_and_polyadenylation_specificity_factor_complex* None None 12 377986 380565 YLR115W S000004105 "ORF,_Verified" "Subunit_of_the_mRNA_cleavage_and_polyadenlylation_factor_(CPF);_required_for_pre-mRNA_cleavage,_polyadenylation_and_poly(A)_site_recognition,_43%_similarity_with_the_mammalian_CPSF-100_protein." YLR116W MSL5 None "nuclear_mRNA_splicing,_via_spliceosome" RNA_binding commitment_complex None None 12 380823 382253 YLR116W S000004106 "ORF,_Verified" "Component_of_the_commitment_complex,_which_defines_the_first_step_in_the_splicing_pathway;_essential_protein_that_interacts_with_Mud2p_and_Prp40p,_forming_a_bridge_between_the_intron_ends;_also_involved_in_nuclear_retention_of_pre-mRNA" YLR117C CLF1 NTC77|SYF3 "nuclear_mRNA_splicing,_via_spliceosome*" protein_binding chromatin None None 12 384535 382472 YLR117C S000004107 "ORF,_Verified" "Essential_splicesome_assembly_factor;_contains_multiple_tetratricopeptide_repeat_(TPR)_protein-binding_motifs_and_interacts_specifically_with_many_spliceosome_components,_may_serve_as_a_scaffold_during_splicesome_assembly" YLR118C None APT1 biological_process_unknown "hydrolase_activity,_acting_on_ester_bonds" cytoplasm* None None 12 385409 384726 YLR118C S000004108 "ORF,_Verified" Acyl-protein_thioesterase_responsible_for_depalmitoylation_of_Gpa1p;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_both_the_cytoplasm_and_nucleus_and_is_induced_in_response_to_the_DNA-damaging_agent_MMS YLR119W SRN2 VPS37|SRN10 protein_targeting_to_vacuole* molecular_function_unknown endosome* None None 12 385535 386176 YLR119W S000004109 "ORF,_Verified" "Component_of_the_ESCRT-I_complex,_which_is_involved_in_ubiquitin-dependent_sorting_of_proteins_into_the_endosome;_suppressor_of_rna1-1_mutation;_may_be_involved_in_RNA_export_from_nucleus" YLR120C YPS1 YAP3 protein_processing aspartic-type_endopeptidase_activity cell_wall_(sensu_Fungi) None None 12 388221 386512 YLR120C S000004110 "ORF,_Verified" "Aspartic_protease,_attached_to_the_plasma_membrane_via_a_glycosylphosphatidylinositol_(GPI)_anchor" YLR121C YPS3 YPS4 protein_metabolism aspartic-type_endopeptidase_activity plasma_membrane G1 None 12 390271 388745 YLR121C S000004111 "ORF,_Verified" "Aspartic_protease,_attached_to_the_plasma_membrane_via_a_glycosylphosphatidylinositol_(GPI)_anchor" YLR125W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 393485 393895 YLR125W S000004115 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_mutant_has_decreased_Ty3_transposition;_YLR125W_is_not_an_essential_gene YLR126C None None biological_process_unknown molecular_function_unknown cytoplasm None None 12 395521 394766 YLR126C S000004116 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_glutamine_amidotransferase_proteins;_has_Aft1p-binding_motif_in_the_promoter;_may_be_involved_in_copper_and_iron_homeostasis;_YLR126C_is_not_an_essential_protein YLR127C APC2 TID2|RSI1 mitotic_sister_chromatid_segregation* protein_binding* anaphase-promoting_complex None None 12 398320 395759 YLR127C S000004117 "ORF,_Verified" "Subunit_of_the_Anaphase-Promoting_Complex/Cyclosome_(APC/C),_which_is_a_ubiquitin-protein_ligase_required_for_degradation_of_anaphase_inhibitors,_including_mitotic_cyclins,_during_the_metaphase/anaphase_transition;_similar_to_cullin_Cdc53p" YLR128W DCN1 None protein_neddylation* enzyme_activator_activity cellular_component_unknown None None 12 398531 399434 YLR128W S000004118 "ORF,_Verified" Putative_Nedd8_ligase;_binds_Nedd8;_involved_in_cullin_neddylation;_not_essential;_similar_to_C.elegans_DCN-1;_contains_UBA-like_ubiquitin-binding_domain_and_a_DUF298_domain YLR129W DIP2 UTP12 processing_of_20S_pre-rRNA snoRNA_binding small_nucleolar_ribonucleoprotein_complex None None 12 399658 402489 YLR129W S000004119 "ORF,_Verified" "Nucleolar_protein,_specifically_associated_with_the_U3_snoRNA,_part_of_the_large_ribonucleoprotein_complex_known_as_the_small_subunit_(SSU)_processome,_required_for_18S_rRNA_biogenesis,_part_of_the_active_pre-rRNA_processing_complex" YLR130C ZRT2 None low-affinity_zinc_ion_transport low-affinity_zinc_ion_transporter_activity plasma_membrane None None 12 404063 402795 YLR130C S000004120 "ORF,_Verified" Low-affinity_zinc_transporter_of_the_plasma_membrane;_transcription_is_induced_under_low-zinc_conditions_by_the_Zap1p_transcription_factor YLR131C ACE2 None G1-specific_transcription_in_mitotic_cell_cycle transcriptional_activator_activity nucleus* G2/M None 12 406823 404511 YLR131C S000004121 "ORF,_Verified" "Transcription_factor_that_activates_expression_of_early_G1-specific_genes,_localizes_to_daughter_cell_nuclei_after_cytokinesis_and_delays_G1_progression_in_daughters,_localization_is_regulated_by_phosphorylation;_potential_Cdc28p_substrate" YLR133W CKI1 None phosphatidylcholine_biosynthesis choline_kinase_activity cytosol None None 12 408446 410194 YLR133W S000004123 "ORF,_Verified" "Choline_kinase,_catalyzing_the_first_step_in_phosphatidylcholine_synthesis_via_the_CDP-choline_(Kennedy_pathway);_exhibits_some_ethanolamine_kinase_activity_contributing_to_phosphatidylethanolamine_synthesis_via_the_CDP-ethanolamine_pathway" YLR134W PDC5 None pyruvate_metabolism* pyruvate_decarboxylase_activity cytoplasm* None None 12 410724 412415 YLR134W S000004124 "ORF,_Verified" "Minor_isoform_of_pyruvate_decarboxylase,_key_enzyme_in_alcoholic_fermentation,_decarboxylates_pyruvate_to_acetaldehyde,_regulation_is_glucose-_and_ethanol-dependent,_repressed_by_thiamine,_involved_in_amino_acid_catabolism" YLR135W SLX4 None DNA_replication* 5'-flap_endonuclease_activity nucleus G1 None 12 413282 415528 YLR135W S000004125 "ORF,_Verified" "Subunit_of_a_complex,_with_Slx1p,_that_hydrolyzes_5'_branches_from_duplex_DNA_in_response_to_stalled_or_converging_replication_forks;_function_overlaps_with_that_of_Sgs1p-Top3p" YLR136C TIS11 CTH2 mRNA_catabolism* mRNA_binding cytoplasm* None Up 12 416659 415802 YLR136C S000004126 "ORF,_Verified" mRNA-binding_protein_expressed_during_iron_starvation;_binds_to_a_sequence_element_in_the_3'-untranslated_regions_of_specific_mRNAs_to_mediate_their_degradation;_involved_in_iron_homeostasis YLR137W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None Up 12 417007 418110 YLR137W S000004127 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YLR138W NHA1 None monovalent_inorganic_cation_homeostasis cation:cation_antiporter_activity* plasma_membrane None None 12 418438 421395 YLR138W S000004128 "ORF,_Verified" Na+/H+_antiporter_involved_in_sodium_and_potassium_efflux_through_the_plasma_membrane;_required_for_alkali_cation_tolerance_at_acidic_pH YLR139C SLS1 None protein_biosynthesis* molecular_function_unknown integral_to_membrane* None None 12 423474 421543 YLR139C S000004129 "ORF,_Verified" Mitochondrial_membrane_protein_that_coordinates_expression_of_mitochondrially-encoded_genes;_may_facilitate_delivery_of_mRNA_to_membrane-bound_translation_machinery YLR141W RRN5 None transcription_from_RNA_polymerase_I_promoter RNA_polymerase_I_transcription_factor_activity* RNA_polymerase_I_upstream_activating_factor_complex None None 12 423684 424775 YLR141W S000004131 "ORF,_Verified" "Protein_involved_in_transcription_of_rDNA_by_RNA_polymerase_I;_transcription_factor,_member_of_UAF_(upstream_activation_factor)_family_along_with_Rrn9p_and_Rrn10p" YLR142W PUT1 None glutamate_biosynthesis* proline_dehydrogenase_activity mitochondrion S/G2 None 12 425187 426617 YLR142W S000004132 "ORF,_Verified" "Proline_oxidase,_nuclear-encoded_mitochondrial_protein_involved_in_utilization_of_proline_as_sole_nitrogen_source;_PUT1_transcription_is_induced_by_Put3p_in_the_presence_of_proline_and_the_absence_of_a_preferred_nitrogen_source" YLR143W None None biological_process_unknown molecular_function_unknown cytoplasm None None 12 427330 429387 YLR143W S000004133 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-tagged_protein_localizes_to_the_cytoplasm;_YLR143W_is_not_an_essential_gene YLR145W RMP1 None rRNA_processing* molecular_function_unknown cytoplasm* None None 12 432169 432774 YLR145W S000004135 "ORF,_Verified" "Subunit_of_RNase_MRP,_which_processes_pre-rRNA_and_has_a_role_in_cell_cycle-regulated_degradation_of_daughter_cell-specific_mRNAs;_unlike_most_subunits,_not_shared_between_RNase_MRP_and_nuclear_RNase_P" YLR146C SPE4 None pantothenate_biosynthesis* spermine_synthase_activity cytoplasm None None 12 433726 432824 YLR146C S000004136 "ORF,_Verified" "Spermine_synthase,_required_for_the_biosynthesis_of_spermine_and_also_involved_in_biosynthesis_of_pantothenic_acid" YLR147C SMD3 SLT16 "nuclear_mRNA_splicing,_via_spliceosome" "RNA_splicing_factor_activity,_transesterification_mechanism*" U4/U6_x_U5_tri-snRNP_complex* None None 12 434464 434159 YLR147C S000004137 "ORF,_Verified" "Core_Sm_protein_Sm_D3;_part_of_heteroheptameric_complex_(with_Smb1p,_Smd1p,_Smd2p,_Sme1p,_Smx3p,_and_Smx2p)_that_is_part_of_the_spliceosomal_U1,_U2,_U4,_and_U5_snRNPs;_homolog_of_human_Sm_D3" YLR148W PEP3 VPT18|VPS18|VAM8 late_endosome_to_vacuole_transport* protein_binding vacuolar_membrane_(sensu_Fungi)* None None 12 434642 437398 YLR148W S000004138 "ORF,_Verified" "Component_of_CORVET_tethering_complex;_vacuolar_peripheral_membrane_protein_that_promotes_vesicular_docking/fusion_reactions_in_conjunction_with_SNARE_proteins,_required_for_vacuolar_biogenesis" YLR149C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None Up 12 439824 437632 YLR149C S000004139 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_overexpression_causes_a_cell_cycle_delay_or_arrest;_null_mutation_results_in_a_decrease_in_plasma_membrane_electron_transport;_YLR149C_is_not_an_essential_gene YLR150W STM1 MPT4 telomere_maintenance* DNA_binding* cytoplasm* None None 12 440468 441289 YLR150W S000004140 "ORF,_Verified" Protein_required_for_optimal_translation_under_nutrient_stress;_involved_in_TOR_signaling_pathway;_binds_G4_quadruplex_and_purine_motif_triplex_nucleic_acid;_acts_with_Cdc13p_to_maintain_telomere_structure YLR151C PCD1 None biological_process_unknown pyrophosphatase_activity peroxisome G1 None 12 442738 441716 YLR151C S000004141 "ORF,_Verified" "Peroxisomal_nudix_pyrophosphatase_with_specificity_for_coenzyme_A_and_CoA_derivatives,_may_function_to_remove_potentially_toxic_oxidized_CoA_disulfide_from_peroxisomes_to_maintain_the_capacity_for_beta-oxidation_of_fatty_acids" YLR154C RNH203 None DNA_replication ribonuclease_H_activity cytoplasm* G1 None 12 448315 447983 YLR154C S000004144 "ORF,_Verified" "Ribonuclease_H2_subunit,_required_for_RNase_H2_activity" YLR155C ASP3-1 ASP3 asparagine_catabolism* asparaginase_activity endoplasmic_reticulum* None Up 12 470406 469318 YLR155C S000004145 "ORF,_Verified" "Cell-wall_L-asparaginase_II,_involved_in_asparagine_catabolism;_expression_is_induced_during_nitrogen_starvation;_four_copies_of_ASP3_are_present_in_the_genome_reference_strain_S288C" YLR156W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 472114 472458 YLR156W S000004146 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_exhibits_a_two-hybrid_interaction_with_Jsn1p_in_a_large-scale_analysis YLR157C-A None None None None None None None 12 481602 480280 YLR157C-A S000007373 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YLR157C-B None None None None None None None 12 481602 476334 YLR157C-B S000007374 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YLR158C ASP3-3 ASP3 asparagine_catabolism* asparaginase_activity periplasmic_space_(sensu_Fungi) None Up 12 483638 482550 YLR158C S000004148 "ORF,_Verified" "Cell-wall_L-asparaginase_II,_involved_in_asparagine_catabolism;_expression_is_induced_during_nitrogen_starvation;_four_copies_of_ASP3_are_present_in_the_genome_reference_strain_S288C" YLR159W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 485346 485690 YLR159W S000004149 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_YLR156W,_YLR159W,_and_YLR161W_are_three_identical_open_reading_frames_encoded_near_the_ribosomal_DNA_region_of_chromosome_12" YLR161W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 488998 489342 YLR161W S000004151 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_YLR156W,_YLR159W,_and_YLR161W_are_three_identical_open_reading_frames_encoded_near_the_ribosomal_DNA_region_of_chromosome_12" YLR162W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 489574 489930 YLR162W S000004152 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_overexpression_confers_resistance_to_the_antimicrobial_peptide_MiAMP1 YLR164W None None biological_process_unknown molecular_function_unknown mitochondrial_inner_membrane None Up 12 493885 494391 YLR164W S000004154 "ORF,_Verified" "Mitochondrial_inner_membrane_of_unknown_function;_similar_to_Tim18p_and_Sdh4p;_expression_induced_by_nitrogen_limitation_in_a_GLN3,_GAT1-dependent_manner" YLR165C PUS5 None rRNA_modification* pseudouridylate_synthase_activity mitochondrion None None 12 495260 494496 YLR165C S000004155 "ORF,_Verified" "Pseudouridine_synthase,_catalyzes_only_the_formation_of_pseudouridine_(Psi)-2819_in_mitochondrial_21S_rRNA;_not_essential_for_viability" YLR166C SEC10 None establishment_of_cell_polarity_(sensu_Fungi)* protein_binding exocyst None None 12 498046 495431 YLR166C S000004156 "ORF,_Verified" "Essential_100kDa_subunit_of_the_exocyst_complex_(Sec3p,_Sec5p,_Sec6p,_Sec8p,_Sec10p,_Sec15p,_Exo70p,_and_Exo84p),_which_has_the_essential_function_of_mediating_polarized_targeting_of_secretory_vesicles_to_active_sites_of_exocytosis" YLR167W RPS31 UBI3|RPS37 protein_biosynthesis* structural_constituent_of_ribosome* cytoplasm* None None 12 498949 499407 YLR167W S000004157 "ORF,_Verified" Fusion_protein_that_is_cleaved_to_yield_a_ribosomal_protein_of_the_small_(40S)_subunit_and_ubiquitin;_ubiquitin_may_facilitate_assembly_of_the_ribosomal_protein_into_ribosomes;_interacts_genetically_with_translation_factor_eIF2B YLR168C None MSF1|MSF1' biological_process_unknown molecular_function_unknown mitochondrion None None 12 500272 499580 YLR168C S000004158 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_that_may_be_involved_in_intramitochondrial_sorting;_similar_to_Ups1p_and_to_human_PRELI;_GFP-tagged_protein_localizes_to_mitochondria;_required_for_wild-type_respiratory_growth YLR170C APS1 YAP19 vesicle-mediated_transport clathrin_binding AP-1_adaptor_complex None None 12 501051 500581 YLR170C S000004160 "ORF,_Verified" "Small_subunit_of_the_clathrin-associated_adaptor_complex_AP-1,_which_is_involved_in_protein_sorting_at_the_trans-Golgi_network;_homolog_of_the_sigma_subunit_of_the_mammalian_clathrin_AP-1_complex" YLR172C DPH5 None peptidyl-diphthamide_biosynthesis_from_peptidyl-histidine diphthine_synthase_activity cytoplasm None None 12 502164 501262 YLR172C S000004162 "ORF,_Verified" "Methyltransferase_required_for_synthesis_of_diphthamide,_which_is_a_modified_histidine_residue_of_translation_elongation_factor_2_(Eft1p_or_Eft2p);_not_essential_for_viability;_GFP-Dph5p_fusion_protein_localizes_to_the_cytoplasm" YLR173W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 502423 504249 YLR173W S000004163 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YLR174W IDP2 None glutamate_biosynthesis* isocitrate_dehydrogenase_(NADP+)_activity cytosol None None 12 504593 505831 YLR174W S000004164 "ORF,_Verified" "Cytosolic_NADP-specific_isocitrate_dehydrogenase,_catalyzes_oxidation_of_isocitrate_to_alpha-ketoglutarate;_levels_are_elevated_during_growth_on_non-fermentable_carbon_sources_and_reduced_during_growth_on_glucose" YLR175W CBF5 None rRNA_modification* pseudouridylate_synthase_activity small_nucleolar_ribonucleoprotein_complex None None 12 506136 507587 YLR175W S000004165 "ORF,_Verified" "Pseudouridine_synthase_catalytic_subunit_of_box_H/ACA_small_nucleolar_ribonucleoprotein_particles_(snoRNPs),_acts_on_both_large_and_small_rRNAs_and_on_snRNA_U2" YLR176C RFX1 CRT1 negative_regulation_of_transcription_from_RNA_polymerase_II_promoter* specific_transcriptional_repressor_activity cytoplasm* None None 12 510234 507799 YLR176C S000004166 "ORF,_Verified" "Major_transcriptional_repressor_of_DNA-damage-regulated_genes,_recruits_repressors_Tup1p_and_Cyc8p_to_their_promoters;_involved_in_DNA_damage_and_replication_checkpoint_pathway;_similar_to_a_family_of_mammalian_DNA_binding_RFX1-4_proteins" YLR177W None None biological_process_unknown molecular_function_unknown cytoplasm None None 12 511056 512942 YLR177W S000004167 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_phosphorylated_by_Dbf2p-Mob1p_in_vitro;_some_strains_contain_microsatellite_polymophisms_at_this_locus;_YLR177W_is_not_an_essential_gene YLR178C TFS1 DKA1 regulation_of_proteolysis lipid_binding* soluble_fraction None Up 12 513823 513164 YLR178C S000004168 "ORF,_Verified" "Carboxypeptidase_Y_inhibitor,_function_requires_acetylation_by_the_NatB_N-terminal_acetyltransferase;_phosphatidylethanolamine-binding_protein_involved_in_protein_kinase_A_signaling_pathway" YLR180W SAM1 ETH10 methionine_metabolism methionine_adenosyltransferase_activity cytoplasm S/G2 Down 12 515264 516412 YLR180W S000004170 "ORF,_Verified" "S-adenosylmethionine_synthetase,_catalyzes_transfer_of_the_adenosyl_group_of_ATP_to_the_sulfur_atom_of_methionine;_one_of_two_differentially_regulated_isozymes_(Sam1p_and_Sam2p)" YLR181C VTA1 None late_endosome_to_vacuole_transport molecular_function_unknown endosome* None None 12 517672 516680 YLR181C S000004171 "ORF,_Verified" "Multivesicular_body_(MVB)_protein_involved_in_endosomal_protein_sorting;_regulates_Vps4p_activity_by_promoting_its_oligomerization;_has_an_N-terminal_Vps60-_and_Did2-_binding_domain,_a_linker_region,_and_a_C-terminal_Vps4p_binding_domain" YLR182W SWI6 SDS11|PSL8 meiosis* protein_binding* cytoplasm* None None 12 517942 520353 YLR182W S000004172 "ORF,_Verified" "Transcription_cofactor,_forms_complexes_with_DNA-binding_proteins_Swi4p_and_Mbp1p_to_regulate_transcription_at_the_G1/S_transition;_involved_in_meiotic_gene_expression;_localization_regulated_by_phosphorylation;_potential_Cdc28p_substrate" YLR183C TOS4 None G1/S-specific_transcription_in_mitotic_cell_cycle transcription_factor_activity cytoplasm* G1 None 12 522014 520545 YLR183C S000004173 "ORF,_Verified" "Transcription_factor_that_binds_to_a_number_of_promoter_regions,_particularly_promoters_of_some_genes_involved_in_pheromone_response_and_cell_cycle;_potential_Cdc28p_substrate;_expression_is_induced_in_G1_by_bound_SBF" YLR185W RPL37A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 12 522665 523290 YLR185W S000004175 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_Rpl37Bp_and_to_rat_L37_ribosomal_protein" YLR186W EMG1 NEP1 35S_primary_transcript_processing* snoRNA_binding cytoplasm* None None 12 523634 524392 YLR186W S000004176 "ORF,_Verified" Member_of_the_alpha/beta_knot_fold_methyltransferase_superfamily;_required_for_maturation_of_18S_rRNA_and_for_40S_ribosome_production;_interacts_with_RNA_and_with_S-adenosylmethionine;_associates_with_spindle/microtubules;_forms_homodimers YLR187W SKG3 None biological_process_unknown molecular_function_unknown cytoplasm* None None 12 524867 527947 YLR187W S000004177 "ORF,_Uncharacterized" "Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cell_periphery,_cytoplasm,_bud,_and_bud_neck;_potential_Cdc28p_substrate;_similar_to_Caf120p_and_Skg4p" YLR189C ATG26 UGT51 sterol_metabolism sterol_3-beta-glucosyltransferase_activity cytoplasm None Up 12 534395 530799 YLR189C S000004179 "ORF,_Verified" "UDP-glucose:sterol_glucosyltransferase,_conserved_enzyme_involved_in_synthesis_of_sterol_glucoside_membrane_lipids;_in_contrast_to_ATG26_from_P._pastoris,_S._cerevisiae_ATG26_is_not_involved_in_autophagy" YLR190W MMR1 None mitochondrion_inheritance molecular_function_unknown mitochondrion* G2/M None 12 535216 536691 YLR190W S000004180 "ORF,_Verified" "Phosphorylated_protein_of_the_mitochondrial_outer_membrane,_localizes_only_to_mitochondria_of_the_bud;_interacts_with_Myo2p_to_mediate_mitochondrial_distribution_to_buds;_mRNA_is_targeted_to_the_bud_via_the_transport_system_involving_She2p" YLR191W PEX13 PAS20 peroxisome_organization_and_biogenesis* protein_binding peroxisomal_membrane None None 12 537274 538434 YLR191W S000004181 "ORF,_Verified" "Integral_peroxisomal_membrane_required_for_the_translocation_of_peroxisomal_matrix_proteins,_interacts_with_the_PTS1_signal_recognition_factor_Pex5p_and_the_PTS2_signal_recognition_factor_Pex7p,_forms_a_complex_with_Pex14p_and_Pex17p" YLR192C HCR1 None protein_biosynthesis* translation_initiation_factor_activity* eukaryotic_translation_initiation_factor_3_complex None None 12 539591 538794 YLR192C S000004182 "ORF,_Verified" Dual_function_protein_involved_in_translation_initiation_as_a_substoichiometric_component_of_eukaryotic_translation_initiation_factor_3_(eIF3)_and_required_for_processing_of_20S_pre-rRNA;_binds_to_eIF3_subunits_Rpg1p_and_Prt1p_and_18S_rRNA YLR193C UPS1 None biological_process_unknown molecular_function_unknown mitochondrion None None 12 540538 540011 YLR193C S000004183 "ORF,_Verified" Mitochondrial_intermembrane_space_protein_that_regulates_alternative_processing_and_sorting_of_Mgm1p_and_other_proteins;_required_for_normal_mitochondrial_morphology;_ortholog_of_human_PRELI YLR194C None None biological_process_unknown molecular_function_unknown cell_wall_(sensu_Fungi) M/G1 None 12 541575 540811 YLR194C S000004184 "ORF,_Uncharacterized" Structural_constituent_of_the_cell_wall_attached_to_the_plasma_membrane_by_a_GPI-anchor;_expression_is_upregulated_in_response_to_cell_wall_stress YLR195C NMT1 CDC72 N-terminal_peptidyl-glycine_N-myristoylation glycylpeptide_N-tetradecanoyltransferase_activity cytosol None None 12 543306 541939 YLR195C S000004185 "ORF,_Verified" "N-myristoyl_transferase,_catalyzes_the_cotranslational,_covalent_attachment_of_myristic_acid_to_the_N-terminal_glycine_residue_of_several_proteins_involved_in_cellular_growth_and_signal_transduction" YLR196W PWP1 None rRNA_processing molecular_function_unknown cytoplasm* None None 12 543970 545700 YLR196W S000004186 "ORF,_Verified" Protein_with_WD-40_repeats_involved_in_rRNA_processing;_associates_with_trans-acting_ribosome_biogenesis_factors;_similar_to_beta-transducin_superfamily YLR197W SIK1 NOP56 rRNA_modification* molecular_function_unknown nucleus* None Down 12 546099 547613 YLR197W S000004187 "ORF,_Verified" Essential_evolutionarily-conserved_nucleolar_protein_component_of_the_box_C/D_snoRNP_complexes_that_direct_2'-O-methylation_of_pre-rRNA_during_its_maturation;_overexpression_causes_spindle_orientation_defects YLR199C PBA1 POC1 biological_process_unknown molecular_function_unknown cytoplasm None Up 12 548771 547855 YLR199C S000004189 "ORF,_Verified" Protein_involved_in_20S_proteasome_assembly;_forms_a_heterodimer_with_Add66p_that_binds_to_proteasome_precursors;_similar_to_human_PAC1_constituent_of_the_PAC1-PAC2_complex_involved_in_proteasome_assembly YLR200W YKE2 PFD6|GIM1 protein_folding* tubulin_binding cytoplasm* None None 12 549014 549358 YLR200W S000004190 "ORF,_Verified" "Subunit_of_the_heterohexameric_Gim/prefoldin_protein_complex_involved_in_the_folding_of_alpha-tubulin,_beta-tubulin,_and_actin" YLR203C MSS51 None protein_biosynthesis* molecular_function_unknown mitochondrion* None None 12 551962 550652 YLR203C S000004193 "ORF,_Verified" Nuclear_encoded_protein_required_for_translation_of_COX1_mRNA;_binds_to_Cox1_protein YLR204W QRI5 COX24 biological_process_unknown molecular_function_unknown mitochondrion None None 12 552272 552607 YLR204W S000004194 "ORF,_Verified" "Mitochondrial_inner_membrane_protein,_required_for_accumulation_of_spliced_COX1_mRNA;_may_have_an_additional_role_in_translation_of_COX1_mRNA" YLR205C HMX1 None iron_ion_homeostasis* heme_binding* endoplasmic_reticulum* None None 12 553679 552726 YLR205C S000004195 "ORF,_Verified" "ER_localized,_heme-binding_peroxidase_involved_in_the_degradation_of_heme;_does_not_exhibit_heme_oxygenase_activity_despite_similarity_to_heme_oxygenases;_expression_regulated_by_AFT1" YLR206W ENT2 None endocytosis* clathrin_binding actin_cortical_patch None None 12 554580 556421 YLR206W S000004196 "ORF,_Verified" Epsin-like_protein_required_for_endocytosis_and_actin_patch_assembly_and_functionally_redundant_with_Ent1p;_contains_clathrin-binding_motif_at_C-terminus YLR207W HRD3 None ER-associated_protein_catabolism ubiquitin-protein_ligase_activity endoplasmic_reticulum None None 12 556790 559291 YLR207W S000004197 "ORF,_Verified" "Resident_protein_of_the_ER_membrane_that_plays_a_central_role_in_ER-associated_protein_degradation_(ERAD),_forms_HRD_complex_with_Hrd1p_and_ERAD_determinants_that_engages_in_lumen_to_cytosol_communication_and_coordination_of_ERAD_events" YLR208W SEC13 ANU3 ER_to_Golgi_transport* structural_molecule_activity cytoplasm* None None 12 559553 560446 YLR208W S000004198 "ORF,_Verified" "Component_of_both_the_Nup84_nuclear_pore_sub-complex_and_of_the_COPII_complex_(Sar1p,_Sec13p,_Sec16p,_Sec23p,_Sec24p,_Sec31p,_Sfb2p,_and_Sfb3p)_which_is_important_for_the_formation_of_ER_to_Golgi_transport_vesicles" YLR210W CLB4 None G2/M_transition_of_mitotic_cell_cycle* cyclin-dependent_protein_kinase_regulator_activity cytoplasm* S/G2 None 12 562010 563392 YLR210W S000004200 "ORF,_Verified" "B-type_cyclin_involved_in_cell_cycle_progression;_activates_Cdc28p_to_promote_the_G2/M_transition;_may_be_involved_in_DNA_replication_and_spindle_assembly;_accumulates_during_S_phase_and_G2,_then_targeted_for_ubiquitin-mediated_degradation" YLR211C None None biological_process_unknown molecular_function_unknown cytoplasm None None 12 564533 563794 YLR211C S000004201 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YLR211C_is_not_an_essential_gene;_ORF_contains_an_intron YLR212C TUB4 None mitotic_spindle_organization_and_biogenesis_in_nucleus* structural_constituent_of_cytoskeleton outer_plaque_of_spindle_pole_body* G1 None 12 566283 564862 YLR212C S000004202 "ORF,_Verified" "Gamma-tubulin,_involved_in_nucleating_microtubules_from_both_the_cytoplasmic_and_nuclear_faces_of_the_spindle_pole_body" YLR213C CRR1 None spore_wall_assembly_(sensu_Fungi) "hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds" spore_wall_(sensu_Fungi) None None 12 567924 566656 YLR213C S000004203 "ORF,_Verified" "Putative_glycoside_hydrolase_of_the_spore_wall_envelope;_required_for_normal_spore_wall_assembly,_possibly_for_cross-linking_between_the_glucan_and_chitosan_layers;_expressed_during_sporulation" YLR214W FRE1 None iron_ion_transport* ferric-chelate_reductase_activity plasma_membrane G2/M Up 12 568569 570629 YLR214W S000004204 "ORF,_Verified" "Ferric_reductase_and_cupric_reductase,_reduces_siderophore-bound_iron_and_oxidized_copper_prior_to_uptake_by_transporters;_expression_induced_by_low_copper_and_iron_levels" YLR215C CDC123 None regulation_of_progression_through_mitotic_cell_cycle molecular_function_unknown cytoplasm None Up 12 571860 570778 YLR215C S000004205 "ORF,_Verified" Protein_involved_in_nutritional_control_of_the_cell_cycle;_regulates_abundance_of_the_translation_initiation_factor_eIF2;_ortholog_of_human_D123_protein YLR216C CPR6 CYP40 protein_folding unfolded_protein_binding* cytoplasm None None 12 573213 572098 YLR216C S000004206 "ORF,_Verified" "Peptidyl-prolyl_cis-trans_isomerase_(cyclophilin),_catalyzes_the_cis-trans_isomerization_of_peptide_bonds_N-terminal_to_proline_residues;_binds_to_Hsp82p_and_contributes_to_chaperone_activity" YLR218C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 12 573920 573468 YLR218C S000004208 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YLR218C_is_not_essential;_mutants_exhibit_glycogen_storage_defects_and_growth_defects_on_a_non-fermentable_carbon_source YLR219W MSC3 None meiotic_recombination molecular_function_unknown cellular_component_unknown None None 12 574153 576339 YLR219W S000004209 "ORF,_Verified" "Protein_of_unknown_function,_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cell_periphery;_msc3_mutants_are_defective_in_directing_meiotic_recombination_events_to_homologous_chromatids;_potential_Cdc28p_substrate" YLR220W CCC1 None iron_ion_homeostasis* manganese_ion_transporter_activity* vacuolar_membrane_(sensu_Fungi)* None None 12 576827 577795 YLR220W S000004210 "ORF,_Verified" "Putative_vacuolar_Fe2+/Mn2+_transporter;_suppresses_respiratory_deficit_of_yfh1_mutants,_which_lack_the_ortholog_of_mammalian_frataxin,_by_preventing_mitochondrial_iron_accumulation" YLR221C RSA3 None ribosomal_large_subunit_assembly_and_maintenance molecular_function_unknown nucleolus* None None 12 579026 578364 YLR221C S000004211 "ORF,_Verified" "Protein_with_a_likely_role_in_ribosomal_maturation,_required_for_accumulation_of_wild-type_levels_of_large_(60S)_ribosomal_subunits;_binds_to_the_helicase_Dbp6p_in_pre-60S_ribosomal_particles_in_the_nucleolus" YLR222C UTP13 None processing_of_20S_pre-rRNA snoRNA_binding small_nucleolar_ribonucleoprotein_complex None None 12 581773 579320 YLR222C S000004212 "ORF,_Verified" "Nucleolar_protein,_component_of_the_small_subunit_(SSU)_processome_containing_the_U3_snoRNA_that_is_involved_in_processing_of_pre-18S_rRNA" YLR223C IFH1 None rRNA_processing* transcription_factor_activity nucleus* None None 12 585492 582235 YLR223C S000004213 "ORF,_Verified" "Essential_protein_with_a_highly_acidic_N-terminal_domain;_IFH1_exhibits_genetic_interactions_with_FHL1,_overexpression_interferes_with_silencing_at_telomeres_and_HM_loci;_potential_Cdc28p_substrate" YLR224W None None ubiquitin-dependent_protein_catabolism protein_binding ubiquitin_ligase_complex None None 12 586466 587575 YLR224W S000004214 "ORF,_Uncharacterized" F-box_protein_and_component_of_SCF_ubiquitin_ligase_complexes_involved_in_ubiquitin-dependent_protein_catabolism;_readily_monoubiquitinated_in_vitro_by_SCF-Ubc4_complexes;_YLR224W_is_not_an_essential_gene YLR225C None None biological_process_unknown molecular_function_unknown cytoplasm S/G2 None 12 588920 587697 YLR225C S000004215 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YLR225C_is_not_an_essential_gene YLR227C ADY4 None sporulation structural_molecule_activity spindle_pole_body None None 12 592045 590564 YLR227C S000004217 "ORF,_Verified" "Structural_component_of_the_meiotic_outer_plaque,_which_is_a_membrane-organizing_center_that_assembles_on_the_cytoplasmic_face_of_the_spindle_pole_body_during_meiosis_II_and_triggers_the_formation_of_the_prospore_membrane" YLR227W-A None None None None None None None 12 593440 594762 YLR227W-A S000007375 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YLR227W-B None None None None None None None 12 593440 598708 YLR227W-B S000007376 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YLR228C ECM22 None sterol_biosynthesis RNA_polymerase_II_transcription_factor_activity nucleus None None 12 602465 600021 YLR228C S000004218 "ORF,_Verified" "Sterol_regulatory_element_binding_protein,_regulates_transcription_of_the_sterol_biosynthetic_genes_ERG2_and_ERG3;_member_of_the_fungus-specific_Zn[2]-Cys[6]_binuclear_cluster_family_of_transcription_factors;_homologous_to_Upc2p" YLR231C BNA5 None NAD_biosynthesis kynureninase_activity cytoplasm* G1 None 12 607121 605760 YLR231C S000004221 "ORF,_Verified" "Kynureninase,_required_for_the_de_novo_biosynthesis_of_NAD_from_tryptophan_via_kynurenine;_expression_regulated_by_Hst1p" YLR233C EST1 None telomerase-dependent_telomere_maintenance RNA_binding* nucleus* G1 None 12 609526 607427 YLR233C S000004223 "ORF,_Verified" "TLC1_RNA-associated_factor_involved_in_telomere_length_regulation_as_the_recruitment_subunit_of_the_telomerase_holoenzyme,_has_a_possible_role_in_activating_Est2p-TLC1-RNA_bound_to_the_telomere" YLR237W THI7 THI10 thiamin_transport thiamin_transporter_activity plasma_membrane None None 12 612369 614165 YLR237W S000004227 "ORF,_Verified" "Plasma_membrane_transporter_responsible_for_the_uptake_of_thiamine,_member_of_the_major_facilitator_superfamily_of_transporters;_mutation_of_human_ortholog_causes_thiamine-responsive_megaloblastic_anemia" YLR239C LIP2 None protein-lipoylation ligase_activity mitochondrion None None 12 617320 616334 YLR239C S000004229 "ORF,_Verified" "Lipoyl_ligase,_involved_in_the_modification_of_mitochondrial_enzymes_by_the_attachment_of_lipoic_acid_groups" YLR240W VPS34 STT8|VPT29|VPL7|PEP15|END12 protein_amino_acid_phosphorylation* protein_kinase_activity* membrane_fraction None None 12 617535 620162 YLR240W S000004230 "ORF,_Verified" Phosphatidylinositol_3-kinase_responsible_for_the_synthesis_of_phosphatidylinositol_3-phosphate;_forms_membrane-associated_signal_transduction_complex_with_Vps15p_to_regulate_protein_sorting;_activated_by_the_GTP-bound_form_of_Gpa1p YLR241W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None Up 12 620475 622823 YLR241W S000004231 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_may_be_involved_in_detoxification" YLR242C ARV1 None sphingolipid_metabolism* molecular_function_unknown endoplasmic_reticulum* None None 12 623885 622920 YLR242C S000004232 "ORF,_Verified" Protein_functioning_in_transport_of_glycosylphosphatidylinositol_intermediates_into_the_ER_lumen;_required_for_normal_intracellular_sterol_distribution_and_for_sphingolipid_metabolism;_similar_to_Nup120p_and_C._elegans_R05H5.5_protein YLR243W None None biological_process_unknown signal_sequence_binding cellular_component_unknown None None 12 624205 625023 YLR243W S000004233 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YLR243W_is_an_essential_gene YLR245C CDD1 None cytidine_catabolism* cytidine_deaminase_activity cytoplasm* None None 12 626932 626504 YLR245C S000004235 "ORF,_Verified" "Cytidine_deaminase;_catalyzes_the_modification_of_cytidine_to_uridine_in_vitro_but_native_RNA_substrates_have_not_been_identified,_localizes_to_both_the_nucleus_and_cytoplasm" YLR246W ERF2 None protein_amino_acid_palmitoylation* protein-cysteine_S-palmitoleyltransferase_activity integral_to_endoplasmic_reticulum_membrane* None None 12 627120 628199 YLR246W S000004236 "ORF,_Verified" "Subunit_of_a_palmitoyltransferase,_composed_of_Erf2p_and_Shr5p,_that_adds_a_palmitoyl_lipid_moiety_to_heterolipidated_substrates_such_as_Ras1p_and_Ras2p_through_a_thioester_linkage;_mutants_partially_mislocalize_Ras2p_to_the_vacuole" YLR247C IRC20 None biological_process_unknown helicase_activity nucleus* None None 12 633356 628686 YLR247C S000004237 "ORF,_Verified" Putative_helicase;_localizes_to_the_mitochondrion_and_the_nucleus;_YLR247C_is_not_an_essential_gene;_null_mutant_displays_increased_levels_of_spontaneous_Rad52p_foci YLR248W RCK2 CMK3|CLK1 protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity cytoplasm None None 12 634254 636086 YLR248W S000004238 "ORF,_Verified" Protein_kinase_involved_in_the_response_to_oxidative_and_osmotic_stress;_identified_as_suppressor_of_S._pombe_cell_cycle_checkpoint_mutations YLR249W YEF3 TEF3 translational_elongation translation_elongation_factor_activity ribosome None None 12 636782 639916 YLR249W S000004239 "ORF,_Verified" "Translational_elongation_factor_3,_stimulates_the_binding_of_aminoacyl-tRNA_(AA-tRNA)_to_ribosomes_by_releasing_EF-1_alpha_from_the_ribosomal_complex;_contains_two_ABC_cassettes;_binds_and_hydrolyses_ATP" YLR251W SYM1 None ethanol_metabolism molecular_function_unknown mitochondrial_inner_membrane None None 12 641466 642059 YLR251W S000004241 "ORF,_Verified" Protein_required_for_ethanol_metabolism;_induced_by_heat_shock_and_localized_to_the_inner_mitochondrial_membrane;_homologous_to_mammalian_peroxisomal_membrane_protein_Mpv17 YLR253W None None biological_process_unknown molecular_function_unknown mitochondrion None None 12 642629 644338 YLR253W S000004243 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_transcription_is_periodic_during_the_metabolic_cycle;_YLR253W_is_not_an_essential_gene" YLR254C NDL1 None "nuclear_migration,_microtubule-mediated" molecular_function_unknown cytoplasm* G2/M None 12 644975 644406 YLR254C S000004244 "ORF,_Verified" "Homolog_of_nuclear_distribution_factor_NudE,_NUDEL;_interacts_with_Pac1p_and_regulates_dynein_targeting_to_microtubule_plus_ends" YLR256W HAP1 CYP1 aerobic_respiration* specific_RNA_polymerase_II_transcription_factor_activity nucleus None None 12 646417 650925 YLR256W S000004246 "ORF,_Verified" Zinc_finger_transcription_factor_involved_in_the_complex_regulation_of_gene_expression_in_response_to_levels_of_heme_and_oxygen;_the_S288C_sequence_differs_from_other_strain_backgrounds_due_to_a_Ty1_insertion_in_the_carboxy_terminus YLR256W-A None None None None None None None 12 651119 652441 YLR256W-A S000007377 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YLR257W None None biological_process_unknown molecular_function_unknown cytoplasm None None 12 658828 659793 YLR257W S000004247 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YLR258W GSY2 None glycogen_biosynthesis glycogen_(starch)_synthase_activity cytoplasm None None 12 660718 662835 YLR258W S000004248 "ORF,_Verified" "Glycogen_synthase,_similar_to_Gsy1p;_expression_induced_by_glucose_limitation,_nitrogen_starvation,_heat_shock,_and_stationary_phase;_activity_regulated_by_cAMP-dependent,_Snf1p_and_Pho85p_kinases_as_well_as_by_the_Gac1p-Glc7p_phosphatase" YLR259C HSP60 MNA2|MIF4|CPN60 protein_folding* single-stranded_DNA_binding mitochondrion* None None 12 665004 663286 YLR259C S000004249 "ORF,_Verified" Tetradecameric_mitochondrial_chaperonin_required_for_ATP-dependent_folding_of_precursor_polypeptides_and_complex_assembly;_prevents_aggregation_and_mediates_protein_refolding_after_heat_shock;_role_in_mtDNA_transmission;_phosphorylated YLR262C YPT6 None intracellular_protein_transport* GTPase_activity Golgi_apparatus None None 12 668893 668246 YLR262C S000004252 "ORF,_Verified" "GTPase,_Ras-like_GTP_binding_protein_involved_in_the_secretory_pathway,_required_for_fusion_of_endosome-derived_vesicles_with_the_late_Golgi,_maturation_of_the_vacuolar_carboxypeptidase_Y;_has_similarity_to_the_human_GTPase,_Rab6" YLR262C-A TMA7 RBF7 biological_process_unknown molecular_function_unknown cytoplasm* None None 12 669664 669470 YLR262C-A S000007246 "ORF,_Verified" "Protein_of_unknown_that_associates_with_ribosomes;_null_mutant_exhibits_translation_defects,_altered_polyribosome_profiles,_and_resistance_to_the_translation_inhibitor_anisomcyin" YLR263W RED1 None synaptonemal_complex_formation* protein_binding* synaptonemal_complex None None 12 670342 672825 YLR263W S000004253 "ORF,_Verified" "Protein_component_of_the_axial_elements_of_the_synaptonemal_complex,_involved_in_chromosome_segregation_during_the_first_meiotic_division;_interacts_with_Hop1p;_required_for_wild-type_levels_of_Mek1p_kinase_activity" YLR264W RPS28B RPS33B protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 12 673133 673336 YLR264W S000004254 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps28Ap_and_has_similarity_to_rat_S28_ribosomal_protein YLR267W BOP2 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 678214 679926 YLR267W S000004257 "ORF,_Uncharacterized" "Protein_of_unknown_function,_overproduction_suppresses_a_pam1_slv3_double_null_mutation" YLR270W DCS1 DcpS deadenylylation-dependent_decapping "hydrolase_activity,_acting_on_acid_anhydrides,_in_phosphorus-containing_anhydrides" cytoplasm* None None 12 681188 682240 YLR270W S000004260 "ORF,_Verified" "Non-essential_hydrolase_involved_in_mRNA_decapping,_may_function_in_a_feedback_mechanism_to_regulate_deadenylation,_contains_pyrophosphatase_activity_and_a_HIT_(histidine_triad)_motif;_interacts_with_neutral_trehalase_Nth1p" YLR271W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 12 682739 683563 YLR271W S000004261 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm_and_the_nucleus_and_is_induced_in_response_to_the_DNA-damaging_agent_MMS YLR272C YCS4 LOC7 mitotic_sister_chromatid_segregation* molecular_function_unknown nucleolus* None None 12 687204 683674 YLR272C S000004262 "ORF,_Verified" "Non-SMC_subunit_of_the_condensin_complex_(Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p);_required_for_establishment_and_maintenance_of_chromosome_condensation,_chromosome_segregation,_chromatin_binding_of_condensin_and_silencing_at_the_mating_type_locus" YLR273C PIG1 None regulation_of_glycogen_biosynthesis protein_phosphatase_type_1_regulator_activity protein_phosphatase_type_1_complex M/G1 None 12 691031 689085 YLR273C S000004263 "ORF,_Verified" Putative_targeting_subunit_for_the_type-1_protein_phosphatase_Glc7p_that_tethers_it_to_the_Gsy2p_glycogen_synthase YLR274W MCM5 CDC46|BOB1 DNA_replication_initiation* chromatin_binding* cytoplasm* M/G1 None 12 691557 693884 YLR274W S000004264 "ORF,_Verified" "Component_of_the_hexameric_MCM_complex,_which_is_important_for_priming_origins_of_DNA_replication_in_G1_and_becomes_an_active_ATP-dependent_helicase_that_promotes_DNA_melting_and_elongation_when_activated_by_Cdc7p-Dbf4p_in_S-phase" YLR275W SMD2 None "nuclear_mRNA_splicing,_via_spliceosome" "RNA_splicing_factor_activity,_transesterification_mechanism" U4/U6_x_U5_tri-snRNP_complex* None None 12 694380 694802 YLR275W S000004265 "ORF,_Verified" "Core_Sm_protein_Sm_D2;_part_of_heteroheptameric_complex_(with_Smb1p,_Smd1p,_Smd3p,_Sme1p,_Smx3p,_and_Smx2p)_that_is_part_of_the_spliceosomal_U1,_U2,_U4,_and_U5_snRNPs;_homolog_of_human_Sm_D2" YLR276C DBP9 None 35S_primary_transcript_processing* ATP-dependent_RNA_helicase_activity nucleolus None None 12 696832 695048 YLR276C S000004266 "ORF,_Verified" ATP-dependent_RNA_helicase_of_the_DEAD-box_family_involved_in_biogenesis_of_the_60S_ribosomal_subunit YLR277C YSH1 BRR5 mRNA_polyadenylylation* RNA_binding* mRNA_cleavage_and_polyadenylation_specificity_factor_complex* None None 12 699497 697158 YLR277C S000004267 "ORF,_Verified" "Putative_endoribonuclease,_subunit_of_the_mRNA_cleavage_and_polyadenylation_specificity_complex_required_for_3'_processing_of_mRNAs" YLR278C None None biological_process_unknown molecular_function_unknown nucleus None None 12 704026 700001 YLR278C S000004268 "ORF,_Uncharacterized" Zinc-cluster_protein;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus;_mutant_shows_moderate_growth_defect_on_caffeine;_YLR278C_is_not_an_essential_gene YLR281C None None biological_process_unknown molecular_function_unknown mitochondrion None None 12 704962 704495 YLR281C S000004271 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_mitochondria;_YLR281C_is_not_an_essential_gene YLR285W NNT1 None chromatin_silencing_at_rDNA* nicotinamide_N-methyltransferase_activity cytoplasm None None 12 707362 708147 YLR285W S000004275 "ORF,_Verified" "Putative_nicotinamide_N-methyltransferase,_has_a_role_in_rDNA_silencing_and_in_lifespan_determination" YLR286C CTS1 None "cytokinesis,_completion_of_separation*" endochitinase_activity endoplasmic_reticulum* M/G1 None 12 710138 708450 YLR286C S000004276 "ORF,_Verified" "Endochitinase,_required_for_cell_separation_after_mitosis;_transcriptional_activation_during_late_G_and_early_M_cell_cycle_phases_is_mediated_by_transcription_factor_Ace2p" YLR287C None None biological_process_unknown molecular_function_unknown cytoplasm None None 12 712060 710993 YLR287C S000004277 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YLR287C_is_not_an_essential_gene YLR287C-A RPS30A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 12 713160 712539 YLR287C-A S000004278 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps30Bp_and_has_similarity_to_rat_S30_ribosomal_protein YLR288C MEC3 PSO9|PIP3 chromatin_silencing_at_telomere* DNA_binding nucleus S/G2 None 12 714906 713482 YLR288C S000004279 "ORF,_Verified" "DNA_damage_and_meiotic_pachytene_checkpoint_protein;_subunit_of_a_heterotrimeric_complex_(Rad17p-Mec3p-Ddc1p)_that_forms_a_sliding_clamp,_loaded_onto_partial_duplex_DNA_by_a_clamp_loader_complex;_homolog_of_human_and_S._pombe_Hus1" YLR290C None None biological_process_unknown molecular_function_unknown mitochondrion None None 12 717980 717147 YLR290C S000004281 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_YLR290C_is_not_an_essential_gene" YLR291C GCD7 None translational_initiation translation_initiation_factor_activity* mitochondrion* None None 12 719464 718319 YLR291C S000004282 "ORF,_Verified" "Beta_subunit_of_the_translation_initiation_factor_eIF2B,_the_guanine-nucleotide_exchange_factor_for_eIF2;_activity_subsequently_regulated_by_phosphorylated_eIF2;_first_identified_as_a_negative_regulator_of_GCN4_expression" YLR293C GSP1 CST17|CNR1 rRNA_processing* GTPase_activity cytoplasm* None None 12 721432 720773 YLR293C S000004284 "ORF,_Verified" "Ran_GTPase,_GTP_binding_protein_(mammalian_Ranp_homolog)_involved_in_the_maintenance_of_nuclear_organization,_RNA_processing_and_transport;_regulated_by_Prp20p,_Rna1p,_Yrb1p,_Yrb2p,_Yrp4p,_Yrb30p,_Cse1p_and_Kap95p;_yeast_Gsp2p_homolog" YLR295C ATP14 None ATP_synthesis_coupled_proton_transport "hydrogen-transporting_ATP_synthase_activity,_rotational_mechanism" "proton-transporting_ATP_synthase_complex,_coupling_factor_F(o)_(sensu_Eukaryota)" None None 12 722375 722001 YLR295C S000004286 "ORF,_Verified" "Subunit_h_of_the_F0_sector_of_mitochondrial_F1F0_ATP_synthase,_which_is_a_large,_evolutionarily_conserved_enzyme_complex_required_for_ATP_synthesis" YLR297W None None biological_process_unknown molecular_function_unknown vacuole_(sensu_Fungi) G2/M None 12 724046 724435 YLR297W S000004288 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_vacuole;_YLR297W_is_not_an_essential_gene;_induced_by_treatment_with_8-methoxypsoralen_and_UVA_irradiation YLR298C YHC1 None "nuclear_mRNA_splicing,_via_spliceosome" mRNA_binding snRNP_U1* None None 12 725418 724723 YLR298C S000004289 "ORF,_Verified" "Component_of_the_U1_snRNP_complex_required_for_pre-mRNA_splicing;_putative_ortholog_of_human_U1C_protein,_which_is_involved_in_formation_of_a_complex_between_U1_snRNP_and_the_pre-mRNA_5'_splice_site" YLR299W ECM38 CIS2 glutathione_catabolism protein-glutamine_gamma-glutamyltransferase_activity intracellular None Up 12 726071 728053 YLR299W S000004290 "ORF,_Verified" "Gamma-glutamyltranspeptidase,_major_glutathione-degrading_enzyme;_involved_in_detoxification_of_electrophilic_xenobiotics;_expression_induced_mainly_by_nitrogen_starvation" YLR300W EXG1 BGL1 cell_wall_organization_and_biogenesis* "glucan_1,3-beta-glucosidase_activity" cell_wall_(sensu_Fungi) G1 None 12 728957 730303 YLR300W S000004291 "ORF,_Verified" "Major_exo-1,3-beta-glucanase_of_the_cell_wall,_involved_in_cell_wall_beta-glucan_assembly;_exists_as_three_differentially_glycosylated_isoenzymes" YLR301W None None cotranslational_protein_targeting_to_membrane molecular_function_unknown endoplasmic_reticulum_membrane None None 12 730827 731561 YLR301W S000004292 "ORF,_Uncharacterized" Protein_of_unknown_function_that_interacts_with_Sec72p YLR303W MET17 MET25|MET15 methionine_metabolism* cysteine_synthase_activity* cytoplasm S/G2 None 12 732544 733878 YLR303W S000004294 "ORF,_Verified" "Methionine_and_cysteine_synthase_(O-acetyl_homoserine-O-acetyl_serine_sulfhydrylase),_required_for_sulfur_amino_acid_synthesis" YLR304C ACO1 GLU1 mitochondrial_genome_maintenance* aconitate_hydratase_activity cytosol* None None 12 737550 735214 YLR304C S000004295 "ORF,_Verified" "Aconitase,_required_for_the_tricarboxylic_acid_(TCA)_cycle_and_also_independently_required_for_mitochondrial_genome_maintenance;_phosphorylated;_component_of_the_mitochondrial_nucleoid;_mutation_leads_to_glutamate_auxotrophy" YLR305C STT4 None actin_cytoskeleton_organization_and_biogenesis* 1-phosphatidylinositol_4-kinase_activity mitochondrion* None None 12 743865 738163 YLR305C S000004296 "ORF,_Verified" "Phosphatidylinositol-4-kinase_that_functions_in_the_Pkc1p_protein_kinase_pathway;_required_for_normal_vacuole_morphology,_cell_wall_integrity,_and_actin_cytoskeleton_organization" YLR306W UBC12 None protein_neddylation NEDD8_conjugating_enzyme_activity cellular_component_unknown None None 12 744153 744853 YLR306W S000004297 "ORF,_Verified" "Enzyme_that_mediates_the_conjugation_of_Rub1p,_a_ubiquitin-like_protein,_to_other_proteins;_related_to_E2_ubiquitin-conjugating_enzymes" YLR308W CDA2 None spore_wall_assembly_(sensu_Fungi) chitin_deacetylase_activity chitosan_layer_of_spore_wall None None 12 747939 748877 YLR308W S000004299 "ORF,_Verified" "Chitin_deacetylase,_together_with_Cda1p_involved_in_the_biosynthesis_ascospore_wall_component,_chitosan;_required_for_proper_rigidity_of_the_ascospore_wall" YLR309C IMH1 SYS3 vesicle-mediated_transport molecular_function_unknown cytosol* None None 12 751771 749036 YLR309C S000004300 "ORF,_Verified" "Protein_involved_in_vesicular_transport,_mediates_transport_between_an_endosomal_compartment_and_the_Golgi,_contains_a_Golgi-localization_(GRIP)_domain_that_interacts_with_activated_Arl1p-GTP_to_localize_Imh1p_to_the_Golgi" YLR310C CDC25 CDC25'|CTN1 regulation_of_progression_through_cell_cycle* Ras_guanyl-nucleotide_exchange_factor_activity cytoplasm* None None 12 756995 752226 YLR310C S000004301 "ORF,_Verified" Membrane_bound_guanine_nucleotide_exchange_factor_(GEF_or_GDP-release_factor);_indirectly_regulates_adenylate_cyclase_through_activation_of_Ras1p_and_Ras2p_by_stimulating_the_exchange_of_GDP_for_GTP;_required_for_progression_through_G1 YLR312C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 758835 757639 YLR312C S000004303 "ORF,_Uncharacterized" Protein_of_unknown_function;_null_mutant_quiescent_and_non-quiescent_cells_exhibit_reduced_reproductive_capacity YLR312W-A MRPL15 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 12 759482 760243 YLR312W-A S000004304 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YLR313C SPH1 YLR312C-B actin_filament_organization* cytoskeletal_regulatory_protein_binding bud_neck* G1 None 12 762342 760357 YLR313C S000004305 "ORF,_Verified" "Protein_involved_in_shmoo_formation_and_bipolar_bud_site_selection;_homologous_to_Spa2p,_localizes_to_sites_of_polarized_growth_in_a_cell_cycle_dependent-_and_Spa2p-dependent_manner,_interacts_with_MAPKKs_Mkk1p,_Mkk2p,_and_Ste7p" YLR314C CDC3 None cell_wall_organization_and_biogenesis* structural_constituent_of_cytoskeleton* prospore_membrane* None None 12 764137 762575 YLR314C S000004306 "ORF,_Verified" "Component_of_the_septin_ring_of_the_mother-bud_neck_that_is_required_for_cytokinesis;_septins_recruit_proteins_to_the_neck_and_can_act_as_a_barrier_to_diffusion_at_the_membrane,_and_they_comprise_the_10nm_filaments_seen_with_EM" YLR315W NKP2 None biological_process_unknown molecular_function_unknown spindle_pole_body* None None 12 764808 765269 YLR315W S000004307 "ORF,_Verified" "Non-essential_kinetochore_protein,_subunit_of_the_Ctf19_central_kinetochore_complex_(Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p)" YLR316C TAD3 None tRNA_modification tRNA_specific_adenosine_deaminase_activity cytoplasm* None None 12 766358 765266 YLR316C S000004308 "ORF,_Verified" "Subunit_of_tRNA-specific_adenosine-34_deaminase,_forms_a_heterodimer_with_Tad2p_that_converts_adenosine_to_inosine_at_the_wobble_position_of_several_tRNAs" YLR319C BUD6 AIP3 actin_filament_organization* cytoskeletal_regulatory_protein_binding actin_cap* None None 12 771684 769318 YLR319C S000004311 "ORF,_Verified" "Actin-_and_formin-interacting_protein,_involved_in_actin_cable_nucleation_and_polarized_cell_growth;_isolated_as_bipolar_budding_mutant;_potential_Cdc28p_substrate" YLR320W MMS22 SLM2 double-strand_break_repair molecular_function_unknown nucleus None None 12 771940 776304 YLR320W S000004312 "ORF,_Verified" Protein_that_acts_with_Mms1p_in_a_repair_pathway_that_may_be_involved_in_resolving_replication_intermediates_or_preventing_the_damage_caused_by_blocked_replication_forks;_required_for_accurate_meiotic_chromosome_segregation YLR321C SFH1 None chromatin_remodeling protein_binding RSC_complex None None 12 777864 776584 YLR321C S000004313 "ORF,_Verified" Component_of_the_RSC_chromatin_remodeling_complex;_essential_gene_required_for_cell_cycle_progression_and_maintenance_of_proper_ploidy;_phosphorylated_in_the_G1_phase_of_the_cell_cycle;_Snf5p_paralog YLR323C CWC24 None biological_process_unknown molecular_function_unknown spliceosome_complex None None 12 778952 778173 YLR323C S000004315 "ORF,_Verified" "Essential_protein,_component_of_a_complex_containing_Cef1p;_has_similarity_to_S._pombe_Cwf24p" YLR324W PEX30 None peroxisome_organization_and_biogenesis molecular_function_unknown peroxisome* None Up 12 779215 780786 YLR324W S000004316 "ORF,_Verified" "Peroxisomal_integral_membrane_protein,_involved_in_negative_regulation_of_peroxisome_number;_partially_functionally_redundant_with_Pex31p;_genetic_interactions_suggest_action_at_a_step_downstream_of_steps_mediated_by_Pex28p_and_Pex29p" YLR325C RPL38 None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 12 781379 781143 YLR325C S000004317 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_rat_L38_ribosomal_protein" YLR326W None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 12 782174 782896 YLR326W S000004318 "ORF,_Uncharacterized" Hypothetical_protein YLR327C TMA10 RBF9 biological_process_unknown molecular_function_unknown cytoplasm* None None 12 783387 783127 YLR327C S000004319 "ORF,_Verified" Protein_of_unknown_function_that_associates_with_ribosomes YLR328W NMA1 None NAD_metabolism nicotinamide-nucleotide_adenylyltransferase_activity cytoplasm* None None 12 784913 786118 YLR328W S000004320 "ORF,_Verified" "Nicotinic_acid_mononucleotide_adenylyltransferase,_involved_in_pathways_of_NAD_biosynthesis,_including_the_de_novo,_NAD(+)_salvage,_and_nicotinamide_riboside_salvage_pathways" YLR329W REC102 None meiotic_recombination* protein_binding nucleus None None 12 786442 787333 YLR329W S000004321 "ORF,_Verified" Protein_involved_in_early_stages_of_meiotic_recombination;_required_for_chromosome_synapsis;_forms_a_complex_with_Rec104p_and_Spo11p_necessary_during_the_initiation_of_recombination YLR330W CHS5 CAL3 spore_wall_assembly_(sensu_Fungi)* molecular_function_unknown cytoplasm None None 12 787664 789679 YLR330W S000004322 "ORF,_Verified" "Component_of_the_exomer_complex,_which_also_contains_Csh6p,_Bch1p,_Bch2p,_and_Bud7p_and_is_involved_in_export_of_selected_proteins,_such_as_chitin_synthase_Chs3p,_from_the_Golgi_to_the_plasma_membrane" YLR332W MID2 KAI1 cell_wall_organization_and_biogenesis* transmembrane_receptor_activity integral_to_plasma_membrane None None 12 790676 791806 YLR332W S000004324 "ORF,_Verified" "O-glycosylated_plasma_membrane_protein_that_acts_as_a_sensor_for_cell_wall_integrity_signaling_and_activates_the_pathway;_interacts_with_Rom2p,_a_guanine_nucleotide_exchange_factor_for_Rho1p,_and_with_cell_integrity_pathway_protein_Zeo1p" YLR333C RPS25B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 12 795899 795573 YLR333C S000004325 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps25Ap_and_has_similarity_to_rat_S25_ribosomal_protein YLR336C SGD1 None osmoregulation molecular_function_unknown nucleus* None None 12 802396 799697 YLR336C S000004328 "ORF,_Verified" Essential_nuclear_protein_with_a_possible_role_in_the_osmoregulatory_glycerol_response;_interacts_with_phospholipase_C_(Plc1p);_putative_homolog_of_human_NOM1_which_is_implicated_in_acute_myeloid_leukemia YLR337C VRP1 YLR337W|MDP2|END5 endocytosis* actin_binding actin_cortical_patch None None 12 805106 802653 YLR337C S000004329 "ORF,_Verified" Proline-rich_actin-associated_protein_involved_in_cytoskeletal_organization_and_cytokinesis;_related_to_mammalian_Wiskott-Aldrich_syndrome_protein_(WASP)-interacting_protein_(WIP) YLR340W RPP0 RPL10E translational_elongation* structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 12 805887 806825 YLR340W S000004332 "ORF,_Verified" "Conserved_ribosomal_protein_P0_similar_to_rat_P0,_human_P0,_and_E._coli_L10e;_shown_to_be_phosphorylated_on_serine_302" YLR341W SPO77 None sporulation_(sensu_Fungi)* molecular_function_unknown intracellular None None 12 807385 808818 YLR341W S000004333 "ORF,_Verified" "Meiosis-specific_protein_of_unknown_function,_required_for_spore_wall_formation_during_sporulation;_dispensable_for_both_nuclear_divisions_during_meiosis" YLR342W FKS1 PBR1|GSC1|ETG1|CWH53|CND1 cell_wall_organization_and_biogenesis* "1,3-beta-glucan_synthase_activity" actin_cortical_patch* G1 None 12 809997 815627 YLR342W S000004334 "ORF,_Verified" "Catalytic_subunit_of_1,3-beta-D-glucan_synthase,_functionally_redundant_with_alternate_catalytic_subunit_Gsc2p;_binds_to_regulatory_subunit_Rho1p;_involved_in_cell_wall_synthesis_and_maintenance;_localizes_to_sites_of_cell_wall_remodeling" YLR343W GAS2 None biological_process_unknown "1,3-beta-glucanosyltransferase_activity" cytoplasm G1 None 12 816094 817761 YLR343W S000004335 "ORF,_Verified" "1,3-beta-glucanosyltransferase,_involved_with_Gas4p_in_spore_wall_assembly;_has_similarity_to_Gas1p" YLR344W RPL26A None protein_biosynthesis structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 12 819312 820142 YLR344W S000004336 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl26Bp_and_has_similarity_to_E._coli_L24_and_rat_L26_ribosomal_proteins;_binds_to_5.8S_rRNA" YLR345W None None biological_process_unknown molecular_function_unknown cytoplasm None None 12 820511 822040 YLR345W S000004337 "ORF,_Uncharacterized" "Similar_to_6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase_enzymes_responsible_for_the_metabolism_of_fructoso-2,6-bisphosphate;_mRNA_expression_is_repressed_by_the_Rfx1p-Tup1p-Ssn6p_repressor_complex;_YLR345W_is_not_an_essential_gene" YLR348C DIC1 None dicarboxylic_acid_transport dicarboxylic_acid_transporter_activity mitochondrial_envelope None Up 12 827872 826976 YLR348C S000004340 "ORF,_Verified" "Mitochondrial_dicarboxylate_carrier,_integral_membrane_protein,_catalyzes_a_dicarboxylate-phosphate_exchange_across_the_inner_mitochondrial_membrane,_transports_cytoplasmic_dicarboxylates_into_the_mitochondrial_matrix" YLR350W ORM2 None response_to_unfolded_protein molecular_function_unknown endoplasmic_reticulum None None 12 828729 829379 YLR350W S000004342 "ORF,_Verified" "Evolutionarily_conserved_protein_with_similarity_to_Orm1p,_required_for_resistance_to_agents_that_induce_the_unfolded_protein_response;_human_ortholog_is_located_in_the_endoplasmic_reticulum" YLR351C NIT3 None biological_process_unknown "hydrolase_activity,_acting_on_carbon-nitrogen_(but_not_peptide)_bonds" cytoplasm* None None 12 830363 829488 YLR351C S000004343 "ORF,_Verified" "Nit_protein,_one_of_two_proteins_in_S._cerevisiae_with_similarity_to_the_Nit_domain_of_NitFhit_from_fly_and_worm_and_to_the_mouse_and_human_Nit_protein_which_interacts_with_the_Fhit_tumor_suppressor;_nitrilase_superfamily_member" YLR352W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 831115 833538 YLR352W S000004344 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_F-box_proteins;_interacts_with_Skp1p_and_Cdc53p;_YLR352W_is_not_an_essential_gene YLR354C TAL1 None pentose-phosphate_shunt transaldolase_activity cytoplasm None None 12 837356 836349 YLR354C S000004346 "ORF,_Verified" "Transaldolase,_enzyme_in_the_non-oxidative_pentose_phosphate_pathway;_converts_sedoheptulose_7-phosphate_and_glyceraldehyde_3-phosphate_to_erythrose_4-phosphate_and_fructose_6-phosphate" YLR355C ILV5 None mitochondrial_genome_maintenance* ketol-acid_reductoisomerase_activity mitochondrion* None None 12 839252 838065 YLR355C S000004347 "ORF,_Verified" "Acetohydroxyacid_reductoisomerase,_mitochondrial_protein_involved_in_branched-chain_amino_acid_biosynthesis,_also_required_for_maintenance_of_wild-type_mitochondrial_DNA_and_found_in_mitochondrial_nucleoids" YLR356W None None biological_process_unknown molecular_function_unknown mitochondrion None None 12 840320 840913 YLR356W S000004348 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_SCM4;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_mitochondria;_YLR356W_is_not_an_essential_gene YLR360W VPS38 VPL17 late_endosome_to_vacuole_transport molecular_function_unknown cellular_component_unknown None None 12 846102 847421 YLR360W S000004352 "ORF,_Verified" Part_of_a_Vps34p_phosphatidylinositol_3-kinase_complex_that_functions_in_carboxypeptidase_Y_(CPY)_sorting;_binds_Vps30p_and_Vps34p_to_promote_production_of_phosphatidylinositol_3-phosphate_(PtdIns3P)_which_stimulates_kinase_activity YLR361C DCR2 None traversing_start_control_point_of_mitotic_cell_cycle "hydrolase_activity,_acting_on_ester_bonds" cellular_component_unknown None None 12 849123 847387 YLR361C S000004353 "ORF,_Verified" "Phosphoesterase_involved_in_downregulation_of_the_unfolded_protein_response,_at_least_in_part_via_dephosphorylation_of_Ire1p;_dosage-dependent_positive_regulator_of_the_G1/S_phase_transition_through_control_of_the_timing_of_START" YLR362W STE11 None protein_amino_acid_phosphorylation* MAP_kinase_kinase_kinase_activity cytoplasm None Up 12 849865 852018 YLR362W S000004354 "ORF,_Verified" "Signal_transducing_MEK_kinase_involved_in_pheromone_response_and_pseudohyphal/invasive_growth_pathways_where_it_phosphorylates_Ste7p,_and_the_high_osmolarity_response_pathway,_via_phosphorylation_of_Pbs2p;_regulated_by_Ste20p_and_Ste50p" YLR363C NMD4 None "mRNA_catabolism,_nonsense-mediated_decay" molecular_function_unknown cytoplasm None None 12 853150 852494 YLR363C S000004355 "ORF,_Verified" "Protein_interacting_with_Nam7p,_may_be_involved_in_the_nonsense-mediated_mRNA_decay_pathway" YLR364W GRX8 None biological_process_unknown molecular_function_unknown cytoplasm None None 12 854061 854390 YLR364W S000004356 "ORF,_Uncharacterized" Putative_cytosolic_dithiol_glutaredoxin;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_non-essential_gene_that_is_strongly_induced_by_arsenic YLR367W RPS22B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 12 856441 857316 YLR367W S000004359 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps22Ap_and_has_similarity_to_E._coli_S8_and_rat_S15a_ribosomal_proteins YLR368W MDM30 DSG1 mitochondrion_organization_and_biogenesis* molecular_function_unknown mitochondrion None None 12 857539 859335 YLR368W S000004360 "ORF,_Verified" "F-box_protein;_physically_associates_with_mitochondria_and_is_required_for_normal_mitochondrial_fusion_in_rich_medium,_during_sporulation,_and_in_mating_cells;_promotes_ubiquitin-mediated_degradation_of_Gal4p_in_some_strains" YLR369W SSQ1 SSC2 DNA-dependent_DNA_replication* unfolded_protein_binding mitochondrial_matrix None None 12 859551 861524 YLR369W S000004361 "ORF,_Verified" "Mitochondrial_hsp70-type_molecular_chaperone,_required_for_assembly_of_iron/sulfur_clusters_into_proteins_at_a_step_after_cluster_synthesis,_and_for_maturation_of_Yfh1p,_which_is_a_homolog_of_human_frataxin_implicated_in_Friedreich's_ataxia" YLR370C ARC18 None actin_filament_organization* structural_constituent_of_cytoskeleton Arp2/3_protein_complex None None 12 862253 861717 YLR370C S000004362 "ORF,_Verified" "Subunit_of_the_ARP2/3_complex,_which_is_required_for_the_motility_and_integrity_of_cortical_actin_patches" YLR371W ROM2 None cell_wall_organization_and_biogenesis* signal_transducer_activity* bud_tip None None 12 862713 866783 YLR371W S000004363 "ORF,_Verified" "GDP/GTP_exchange_protein_(GEP)_for_Rho1p_and_Rho2p;_mutations_are_synthetically_lethal_with_mutations_in_rom1,_which_also_encodes_a_GEP" YLR372W SUR4 APA1|VBM1|SRE1|ELO3 sphingolipid_biosynthesis* fatty_acid_elongase_activity endoplasmic_reticulum* G1 Down 12 867353 868390 YLR372W S000004364 "ORF,_Verified" "Elongase,_involved_in_fatty_acid_and_sphingolipid_biosynthesis;_synthesizes_very_long_chain_20-26-carbon_fatty_acids_from_C18-CoA_primers;_involved_in_regulation_of_sphingolipid_biosynthesis" YLR375W STP3 None biological_process_unknown molecular_function_unknown nucleus None None 12 871696 872727 YLR375W S000004367 "ORF,_Verified" "Zinc-finger_protein_of_unknown_function,_possibly_involved_in_pre-tRNA_splicing_and_in_uptake_of_branched-chain_amino_acids" YLR377C FBP1 ACN8 gluconeogenesis fructose-bisphosphatase_activity cytosol None None 12 874791 873745 YLR377C S000004369 "ORF,_Verified" "Fructose-1,6-bisphosphatase,_key_regulatory_enzyme_in_the_gluconeogenesis_pathway,_required_for_glucose_metabolism;_undergoes_either_proteasome-mediated_or_autophagy-mediated_degradation_depending_on_growth_conditions;_interacts_with_Vid30p" YLR380W CSR1 SFH2 cell_wall_organization_and_biogenesis* phosphatidylinositol_transporter_activity cytoplasm* G1 None 12 878282 879508 YLR380W S000004372 "ORF,_Verified" Phosphatidylinositol_transfer_protein_with_a_potential_role_in_regulating_lipid_and_fatty_acid_metabolism_under_heme-depleted_conditions;_interacts_specifically_with_thioredoxin_peroxidase;_may_have_a_role_in_oxidative_stress_resistance YLR382C NAM2 MSL1 Group_I_intron_splicing* mRNA_binding* mitochondrion None None 12 884751 882067 YLR382C S000004374 "ORF,_Verified" "Mitochondrial_leucyl-tRNA_synthetase,_also_has_a_direct_role_in_splicing_of_several_mitochondrial_group_I_introns;_indirectly_required_for_mitochondrial_genome_maintenance" YLR383W SMC6 RHC18 DNA_repair* molecular_function_unknown nucleus* G1 None 12 885288 888632 YLR383W S000004375 "ORF,_Verified" "Protein_involved_in_structural_maintenance_of_chromosomes;_essential_subunit_of_Mms21-Smc5-Smc6_complex;_required_for_growth,_DNA_repair,_interchromosomal_and_sister_chromatid_recombination;_homologous_to_S._pombe_rad18" YLR384C IKI3 KTI7|TOT1|ELP1 regulation_of_transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_elongation_factor_activity* transcription_elongation_factor_complex* None None 12 892900 888851 YLR384C S000004376 "ORF,_Verified" "Subunit_of_Elongator_complex,_which_is_required_for_modification_of_wobble_nucleosides_in_tRNA;_maintains_structural_integrity_of_Elongator;_homolog_of_human_IKAP,_mutations_in_which_cause_familial_dysautonomia_(FD)" YLR385C SWC7 AWS1 chromatin_remodeling molecular_function_unknown nucleus* None None 12 893390 892992 YLR385C S000004377 "ORF,_Verified" "Protein_of_unknown_function,_component_of_the_Swr1p_complex_that_incorporates_Htz1p_into_chromatin" YLR386W VAC14 None vacuole_inheritance* enzyme_activator_activity vacuolar_membrane_(sensu_Fungi)* None None 12 893628 896270 YLR386W S000004378 "ORF,_Verified" "Protein_involved_in_regulated_synthesis_of_PtdIns(3,5)P(2),_in_control_of_trafficking_of_some_proteins_to_the_vacuole_lumen_via_the_MVB,_and_in_maintenance_of_vacuole_size_and_acidity;_interacts_with_Fig4p;_activator_of_Fab1p" YLR387C REH1 None biological_process_unknown* molecular_function_unknown cytoplasm None Up 12 897672 896374 YLR387C S000004379 "ORF,_Verified" "Protein_of_unknown_function,_similar_to_Rei1p_but_not_involved_in_bud_growth;_contains_dispersed_C2H2_zinc_finger_domains" YLR388W RPS29A YS29A protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 12 898651 898821 YLR388W S000004380 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps29Bp_and_has_similarity_to_rat_S29_and_E._coli_S14_ribosomal_proteins YLR390W ECM19 None cell_wall_organization_and_biogenesis molecular_function_unknown cellular_component_unknown None None 12 903066 903404 YLR390W S000004382 "ORF,_Verified" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies" YLR390W-A CCW14 YLR391W|SSR1|YLR391W-A cell_wall_organization_and_biogenesis structural_constituent_of_cell_wall mitochondrion* None None 12 903724 904440 YLR390W-A S000006429 "ORF,_Verified" "Covalently_linked_cell_wall_glycoprotein,_present_in_the_inner_layer_of_the_cell_wall" YLR393W ATP10 None protein_complex_assembly chaperone_binding mitochondrial_envelope None None 12 907079 907918 YLR393W S000004385 "ORF,_Verified" "Mitochondrial_inner_membrane_protein_required_for_assembly_of_the_F0_sector_of_mitochondrial_F1F0_ATP_synthase,_interacts_genetically_with_ATP6" YLR394W CST9 ZIP3 synapsis* DNA_binding nuclear_chromosome None None 12 907950 909398 YLR394W S000004386 "ORF,_Verified" SUMO_E3_ligase;_required_for_synaptonemal_complex_formation;_localizes_to_synapsis_initiation_sites_on_meiotic_chromosomes;_potential_Cdc28p_substrate YLR395C COX8 None aerobic_respiration* cytochrome-c_oxidase_activity respiratory_chain_complex_IV_(sensu_Eukaryota) None None 12 909965 909729 YLR395C S000004387 "ORF,_Verified" "Subunit_VIII_of_cytochrome_c_oxidase,_which_is_the_terminal_member_of_the_mitochondrial_inner_membrane_electron_transport_chain" YLR396C VPS33 VPT33|VPL25|VAM5|SLP1|PEP14|MET27|CLS14 late_endosome_to_vacuole_transport* ATP_binding cytosol* None None 12 912310 910235 YLR396C S000004388 "ORF,_Verified" ATP-binding_protein_that_is_a_subunit_of_the_HOPS_complex_and_the_CORVET_tethering_complex;_essential_for_membrane_docking_and_fusion_at_both_the_Golgi-to-endosome_and_endosome-to-vacuole_stages_of_protein_transport YLR397C AFG2 DRG1 response_to_drug ATPase_activity intracellular None None 12 914892 912550 YLR397C S000004389 "ORF,_Verified" "ATPase_of_the_CDC48/PAS1/SEC18_(AAA)_family,_forms_a_hexameric_complex;_may_be_involved_in_degradation_of_aberrant_mRNAs" YLR398C SKI2 None mRNA_catabolism* RNA_helicase_activity* cytoplasm* None None 12 919019 915156 YLR398C S000004390 "ORF,_Verified" "Putative_RNA_helicase,_involved_in_exosome_mediated_3'_to_5'_mRNA_degradation_and_translation_inhibition_of_non-poly(A)_mRNAs;_forms_complex_with_Ski3p_and_Ski8p;_required_for_repressing_propagation_of_dsRNA_viruses" YLR399C BDF1 None DNA_repair* transcription_regulator_activity nucleus* None None 12 921596 919536 YLR399C S000004391 "ORF,_Verified" Protein_involved_in_transcription_initiation_at_TATA-containing_promoters;_associates_with_the_basal_transcription_factor_TFIID;_contains_two_bromodomains;_corresponds_to_the_C-terminal_region_of_mammalian_TAF1;_redundant_with_Bdf2p YLR401C DUS3 None tRNA_modification tRNA_dihydrouridine_synthase_activity cytoplasm* None None 12 924448 922442 YLR401C S000004393 "ORF,_Verified" "Dihydrouridine_synthase,_member_of_a_widespread_family_of_conserved_proteins_including_Smm1p,_Dus1p,_and_Dus4p;_contains_a_consensus_oleate_response_element_(ORE)_in_its_promoter_region" YLR404W FLD1 SEI1 biological_process_unknown molecular_function_unknown integral_to_membrane None None 12 928742 929599 YLR404W S000004396 "ORF,_Verified" "Seipin_protein_involved_in_lipid_droplet_morphology,_number,_and_size;_proposed_to_be_involved_in_lipid_metabolism;_related_to_the_human_BSCL2_which_is_associated_with_lipodystrophy" YLR405W DUS4 None tRNA_modification tRNA_dihydrouridine_synthase_activity cellular_component_unknown None None 12 929788 930891 YLR405W S000004397 "ORF,_Verified" "Dihydrouridine_synthase,_member_of_a_widespread_family_of_conserved_proteins_including_Smm1p,_Dus1p,_and_Dus3p" YLR406C RPL31B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 12 931754 931064 YLR406C S000004398 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl31Ap_and_has_similarity_to_rat_L31_ribosomal_protein;_associates_with_the_karyopherin_Sxm1p" YLR410W VIP1 None actin_cytoskeleton_organization_and_biogenesis molecular_function_unknown cytoplasm None None 12 937539 940979 YLR410W S000004402 "ORF,_Verified" "Inositol_hexakisphosphate_(IP6)_and_inositol_heptakisphosphate_(IP7)_kinase;_generation_of_IP7_by_Vip1p_is_important_for_phosphate_signaling;_likely_involved_in_cortical_actin_cytoskeleton_function,_by_analogy_with_S._pombe_ortholog_asp1" YLR410W-A None None None None None None None 12 941481 942797 YLR410W-A S000007379 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YLR410W-B None None None None None None None 12 941481 946794 YLR410W-B S000007380 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YLR411W CTR3 None copper_ion_import copper_uptake_transporter_activity integral_to_plasma_membrane None None 12 947251 947976 YLR411W S000004403 "ORF,_Verified" "High-affinity_copper_transporter_of_the_plasma_membrane,_acts_as_a_trimer;_gene_is_disrupted_by_a_Ty2_transposon_insertion_in_many_laboratory_strains_of_S._cerevisiae" YLR413W None None biological_process_unknown molecular_function_unknown cellular_component_unknown G2/M None 12 951153 953180 YLR413W S000004405 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YLR413W_is_not_an_essential_gene YLR414C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 12 954141 953350 YLR414C S000004406 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_bud_and_cytoplasm;_Hog1p_is_required_for_transcriptional_induction_in_response_to_cell_wall_damage;_YLR414C_is_not_an_essential_gene YLR415C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 954594 954256 YLR415C S000004407 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YLR415C_is_not_an_essential_gene YLR417W VPS36 VPL11|VAC3|GRD12 protein_targeting_to_vacuole* regulator_of_G-protein_signaling_activity ESCRT_II_complex None None 12 955007 956707 YLR417W S000004409 "ORF,_Verified" Component_of_the_ESCRT-II_complex;_contains_the_GLUE_(GRAM_Like_Ubiquitin_binding_in_EAP45)_domain_which_is_involved_in_interactions_with_ESCRT-I_and_ubiquitin-dependent_sorting_of_proteins_into_the_endosome YLR418C CDC73 None DNA_recombination* RNA_polymerase_II_transcription_elongation_factor_activity nucleus* None None 12 958092 956911 YLR418C S000004410 "ORF,_Verified" "Constituent_of_Paf1_complex_with_RNA_polymerase_II,_Paf1p,_Hpr1p,_Ctr9,_Leo1,_Rtf1_and_Ccr4p,_distinct_from_Srb-containing_Pol_II_complexes;_required_for_expression_of_certain_genes,_modification_of_some_histones,_and_telomere_maintenance" YLR419W None None biological_process_unknown helicase_activity cytoplasm* None None 12 958425 962732 YLR419W S000004411 "ORF,_Uncharacterized" "Putative_helicase_with_limited_sequence_similarity_to_human_Rb_protein;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_YLR419W_is_not_an_essential_gene" YLR420W URA4 None de_novo'_pyrimidine_base_biosynthesis* dihydroorotase_activity cytoplasm* None None 12 963782 964876 YLR420W S000004412 "ORF,_Verified" "Dihydroorotase,_catalyzes_the_third_enzymatic_step_in_the_de_novo_biosynthesis_of_pyrimidines,_converting_carbamoyl-L-aspartate_into_dihydroorotate" YLR421C RPN13 None proteolysis endopeptidase_activity "proteasome_regulatory_particle,_lid_subcomplex_(sensu_Eukaryota)" None None 12 965557 965087 YLR421C S000004413 "ORF,_Verified" Subunit_of_the_19S_regulatory_particle_of_the_26S_proteasome_lid;_acts_as_a_ubiquitin_receptor_for_the_proteasome YLR422W None None biological_process_unknown molecular_function_unknown cytoplasm None None 12 965894 971692 YLR422W S000004414 "ORF,_Uncharacterized" "Protein_of_unknown_function_with_similarity_to_human_DOCK_proteins_(guanine_nucleotide_exchange_factors);_interacts_with_Ino4p;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm,_YLR422W_is_not_an_essential_protein" YLR423C ATG17 APG17 autophagy kinase_activator_activity cytoplasm None None 12 973167 971914 YLR423C S000004415 "ORF,_Verified" Scaffold_protein_responsible_for_phagophore_assembly_site_organization;_regulatory_subunit_of_an_autophagy-specific_complex_that_includes_Atg1p_and_Atg13p;_stimulates_Atg1p_kinase_activity YLR424W SPP382 NTR1|CCF8 "nuclear_mRNA_splicing,_via_spliceosome" RNA_binding cytoplasm* None None 12 973392 975518 YLR424W S000004416 "ORF,_Verified" "Essential_protein_that_forms_a_dimer_with_Ntr2p;_also_forms_a_trimer,_with_Ntr2p_and_Prp43p,_that_is_involved_in_spliceosome_disassembly;_found_also_in_a_multisubunit_complex_with_the_splicing_factor_Clf1p;_suppressor_of_prp38-1_mutation" YLR425W TUS1 SOP10 cell_wall_organization_and_biogenesis* Rho_guanyl-nucleotide_exchange_factor_activity cellular_component_unknown None None 12 982891 986814 YLR425W S000004417 "ORF,_Verified" Guanine_nucleotide_exchange_factor_(GEF)_that_functions_to_modulate_Rho1p_activity_as_part_of_the_cell_integrity_signaling_pathway;_multicopy_suppressor_of_tor2_mutation_and_ypk1_ypk2_double_mutation;_potential_Cdc28p_substrate YLR426W None None biological_process_unknown molecular_function_unknown mitochondrion None None 12 987059 988110 YLR426W S000004418 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_proposed_to_be_involved_in_resistance_to_mechlorethamine_and_streptozotocin" YLR427W MAG2 None DNA_dealkylation alkylbase_DNA_N-glycosylase_activity cytoplasm None None 12 988425 990437 YLR427W S000004419 "ORF,_Verified" Cytoplasmic_protein_of_unknown_function_predicted_to_encode_a_DNA-3-methyladenine_glycosidase_II_that_catalyzes_the_hydrolysis_of_alkylated_DNA YLR429W CRN1 None actin_filament_organization* "protein_binding,_bridging*" actin_cortical_patch None None 12 990774 992729 YLR429W S000004421 "ORF,_Verified" "Coronin,_cortical_actin_cytoskeletal_component_that_associates_with_the_Arp2p/Arp3p_complex_to_regulate_its_activity;_plays_a_role_in_regulation_of_actin_patch_assembly" YLR430W SEN1 NRD2|CIK3 35S_primary_transcript_processing ATP-dependent_RNA_helicase_activity nucleus None None 12 993431 1000126 YLR430W S000004422 "ORF,_Verified" Presumed_helicase_required_for_RNA_polymerase_II_transcription_termination_and_processing_of_RNAs;_homolog_of_Senataxin_which_causes_Ataxia-Oculomotor_Apraxia_2_and_a_dominant_form_of_amyotrophic_lateral_sclerosis YLR431C ATG23 CVT23 protein_targeting_to_vacuole* molecular_function_unknown extrinsic_to_membrane None None 12 1001700 1000339 YLR431C S000004423 "ORF,_Verified" Peripheral_membrane_protein_required_for_the_cytoplasm-to-vacuole_targeting_(Cvt)_pathway_and_efficient_macroautophagy;_cycles_between_the_phagophore_assembly_site_(PAS)_and_non-PAS_locations;_forms_a_complex_with_Atg9p_and_Atg27p YLR432W IMD3 None GTP_biosynthesis IMP_dehydrogenase_activity cytoplasm None None 12 1002554 1004125 YLR432W S000004424 "ORF,_Verified" "Inosine_monophosphate_dehydrogenase,_catalyzes_the_first_step_of_GMP_biosynthesis,_member_of_a_four-gene_family_in_S._cerevisiae,_constitutively_expressed" YLR433C CNA1 CMP1 cell_wall_organization_and_biogenesis* calcium-dependent_protein_serine/threonine_phosphatase_activity cytoplasm* None None 12 1006005 1004344 YLR433C S000004425 "ORF,_Verified" "Calcineurin_A;_one_isoform_(the_other_is_CMP2)_of_the_catalytic_subunit_of_calcineurin,_a_Ca++/calmodulin-regulated_protein_phosphatase_which_regulates_Crz1p_(a_stress-response_transcription_factor),_the_other_calcineurin_subunit_is_CNB1" YLR435W TSR2 None processing_of_20S_pre-rRNA molecular_function_unknown cytoplasm* None None 12 1006375 1006992 YLR435W S000004427 "ORF,_Verified" Protein_with_a_potential_role_in_pre-rRNA_processing YLR436C ECM30 None cell_wall_organization_and_biogenesis molecular_function_unknown cytoplasm None None 12 1011242 1007418 YLR436C S000004428 "ORF,_Verified" Non-essential_protein_of_unknown_function YLR437C None None biological_process_unknown molecular_function_unknown cytoplasm S/G2 None 12 1012020 1011619 YLR437C S000004429 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_epitope_tagged_protein_localizes_to_the_cytoplasm YLR438C-A LSM3 USS2|SMX4 "nuclear_mRNA_splicing,_via_spliceosome*" RNA_binding nucleolus* None None 12 1014175 1013906 YLR438C-A S000006434 "ORF,_Verified" "Lsm_(Like_Sm)_protein;_part_of_heteroheptameric_complexes_(Lsm2p-7p_and_either_Lsm1p_or_8p):_cytoplasmic_Lsm1p_complex_involved_in_mRNA_decay;_nuclear_Lsm8p_complex_part_of_U6_snRNP_and_possibly_involved_in_processing_tRNA,_snoRNA,_and_rRNA" YLR438W CAR2 cargB arginine_catabolism ornithine-oxo-acid_transaminase_activity cytoplasm* G2/M None 12 1012498 1013772 YLR438W S000004430 "ORF,_Verified" "L-ornithine_transaminase_(OTAse),_catalyzes_the_second_step_of_arginine_degradation,_expression_is_dually-regulated_by_allophanate_induction_and_a_specific_arginine_induction_process;_not_nitrogen_catabolite_repression_sensitive" YLR439W MRPL4 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 12 1014488 1015447 YLR439W S000004431 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YLR440C SEC39 DSL3 secretory_pathway molecular_function_unknown endoplasmic_reticulum* None None 12 1017694 1015565 YLR440C S000004432 "ORF,_Verified" Protein_of_unknown_function_proposed_to_be_involved_in_protein_secretion;_interacts_with_Dsl1p_and_localizes_to_the_ER_and_nuclear_envelope YLR441C RPS1A RP10A protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 12 1018905 1018138 YLR441C S000004433 "ORF,_Verified" Ribosomal_protein_10_(rp10)_of_the_small_(40S)_subunit;_nearly_identical_to_Rps1Bp_and_has_similarity_to_rat_S3a_ribosomal_protein YLR442C SIR3 STE8|MAR2|CMT1 double-strand_break_repair_via_nonhomologous_end-joining* histone_binding* mitochondrion* None None 12 1022248 1019312 YLR442C S000004434 "ORF,_Verified" "Silencing_protein_that_interacts_with_Sir2p_and_Sir4p,_and_histone_H3_and_H4_tails,_to_establish_a_transcriptionally_silent_chromatin_state;_required_for_spreading_of_silenced_chromatin;_recruited_to_chromatin_through_interaction_with_Rap1p" YLR443W ECM7 ZRG15 cell_wall_organization_and_biogenesis molecular_function_unknown integral_to_membrane None None 12 1022622 1023968 YLR443W S000004435 "ORF,_Verified" Non-essential_putative_integral_membrane_protein;_mutant_has_cell_wall_defects;_transcription_is_induced_under_conditions_of_zinc_deficiency YLR445W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 1024186 1024834 YLR445W S000004437 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_transcription_is_regulated_by_Ume6p_and_induced_in_response_to_alpha_factor YLR446W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 1025211 1026512 YLR446W S000004438 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_hexokinases;_transcript_is_upregulated_during_sporulation_and_the_unfolded_protein_response;_YLR446W_is_not_an_essential_gene YLR447C VMA6 None vacuolar_acidification* "hydrogen-transporting_ATPase_activity,_rotational_mechanism" vacuolar_membrane* None None 12 1027890 1026853 YLR447C S000004439 "ORF,_Verified" "Subunit_d_of_the_five-subunit_V0_integral_membrane_domain_of_vacuolar_H+-ATPase_(V-ATPase),_an_electrogenic_proton_pump_found_in_the_endomembrane_system;_stabilizes_VO_subunits;_required_for_V1_domain_assembly_on_the_vacuolar_membrane" YLR448W RPL6B None protein_biosynthesis* structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 12 1028850 1029764 YLR448W S000004440 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_Rpl6Ap_and_to_rat_L6_ribosomal_protein;_binds_to_5.8S_rRNA" YLR449W FPR4 None biological_process_unknown peptidyl-prolyl_cis-trans_isomerase_activity nucleus None None 12 1030830 1032008 YLR449W S000004441 "ORF,_Verified" "Peptidyl-prolyl_cis-trans_isomerase_(PPIase)_(proline_isomerase)_localized_to_the_nucleus;_catalyzes_isomerization_of_proline_residues_in_histones_H3_and_H4,_which_affects_lysine_methylation_of_those_histones" YLR450W HMG2 None ergosterol_biosynthesis hydroxymethylglutaryl-CoA_reductase_(NADPH)_activity endoplasmic_reticulum_membrane* None None 12 1032624 1035761 YLR450W S000004442 "ORF,_Verified" "One_of_two_isozymes_of_HMG-CoA_reductase_that_convert_HMG-CoA_to_mevalonate,_a_rate-limiting_step_in_sterol_biosynthesis;_overproduction_induces_assembly_of_peripheral_ER_membrane_arrays_and_short_nuclear-associated_membrane_stacks" YLR451W LEU3 None regulation_of_transcription_from_RNA_polymerase_II_promoter* specific_RNA_polymerase_II_transcription_factor_activity nucleus None None 12 1036090 1038750 YLR451W S000004443 "ORF,_Verified" "Zinc-finger_transcription_factor_that_regulates_genes_involved_in_branched_chain_amino_acid_biosynthesis_and_ammonia_assimilation;_positively_regulated_by_alpha-isopropylmalate,_an_intermediate_in_leucine_biosynthesis" YLR452C SST2 None signal_transduction* GTPase_activator_activity plasma_membrane M/G1 None 12 1041364 1039268 YLR452C S000004444 "ORF,_Verified" "GTPase-activating_protein_for_Gpa1p,_regulates_desensitization_to_alpha_factor_pheromone;_also_required_to_prevent_receptor-independent_signaling_of_the_mating_pathway;_member_of_the_RGS_(regulator_of_G-protein_signaling)_family" YLR455W None None biological_process_unknown molecular_function_unknown nucleus S None 12 1053627 1054541 YLR455W S000004447 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus;_deletion_confers_sensitivity_to_4-(N-(S-glutathionylacetyl)amino)_phenylarsenoxide_(GSAO) YLR456W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 1055068 1055682 YLR456W S000004448 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_null_mutant_displays_increased_resistance_to_antifungal_agents_gliotoxin,_cycloheximide_and_H2O2" YLR459W GAB1 CDC91 attachment_of_GPI_anchor_to_protein GPI-anchor_transamidase_activity GPI-anchor_transamidase_complex G1 None 12 1057332 1058516 YLR459W S000004451 "ORF,_Verified" "GPI_transamidase_subunit,_involved_in_attachment_of_glycosylphosphatidylinositol_(GPI)_anchors_to_proteins;_may_have_a_role_in_recognition_of_the_attachment_signal_or_of_the_lipid_portion_of_GPI" YLR461W PAU4 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 12 1062917 1063279 YLR461W S000004453 "ORF,_Verified" "Part_of_23-member_seripauperin_multigene_family_encoded_mainly_in_subtelomeric_regions,_active_during_alcoholic_fermentation,_regulated_by_anaerobiosis,_negatively_regulated_by_oxygen,_repressed_by_heme" YLR462W None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 12 1065954 1066562 YLR462W S000004454 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_helicases;_YLR462W_is_within_the_telomere_on_the_right_arm_of_chromosome_XII YLR464W None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 12 1066570 1067499 YLR464W S000004456 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_intron_is_predicted_but_not_detected_experimentally;_YLR464W_overlaps_the_verified_gene_YRF1-4/YLR466W_and_two_dubious_ORFs_YLR463C_and_YLR465C YLR466W YRF1-4 YRF1 telomerase-independent_telomere_maintenance DNA_helicase_activity nucleus M/G1 None 12 1067085 1071233 YLR466W S000004458 "ORF,_Verified" "Helicase_encoded_by_the_Y'_element_of_subtelomeric_regions,_highly_expressed_in_the_mutants_lacking_the_telomerase_component_TLC1;_potentially_phosphorylated_by_Cdc28p" YLR467W YRF1-5 YRF1 telomerase-independent_telomere_maintenance DNA_helicase_activity nucleus G1 None 12 1072506 1077896 YLR467W S000004459 "ORF,_Verified" "Helicase_encoded_by_the_Y'_element_of_subtelomeric_regions,_highly_expressed_in_the_mutants_lacking_the_telomerase_component_TLC1;_potentially_phosphorylated_by_Cdc28p" YML001W YPT7 VAM4|AST4 vesicle-mediated_transport* GTPase_activity vacuole None None 13 267174 267800 YML001W S000004460 "ORF,_Verified" "GTPase;_GTP-binding_protein_of_the_rab_family;_required_for_homotypic_fusion_event_in_vacuole_inheritance,_for_endosome-endosome_fusion,_similar_to_mammalian_Rab7" YML002W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 264541 266754 YML002W S000004461 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_expression_induced_by_heat_and_by_calcium_shortage YML003W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 263483 264355 YML003W S000004462 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YML004C GLO1 None glutathione_metabolism* lactoylglutathione_lyase_activity cytoplasm* None None 13 262685 261705 YML004C S000004463 "ORF,_Verified" "Monomeric_glyoxalase_I,_catalyzes_the_detoxification_of_methylglyoxal_(a_by-product_of_glycolysis)_via_condensation_with_glutathione_to_produce_S-D-lactoylglutathione;_expression_regulated_by_methylglyoxal_levels_and_osmotic_stress" YML005W TRM12 TYW2 tRNA_methylation S-adenosylmethionine-dependent_methyltransferase_activity cytoplasm None None 13 260221 261609 YML005W S000004464 "ORF,_Verified" S-adenosylmethionine-dependent_methyltransferase_of_the_seven_beta-strand_family;_required_for_wybutosine_formation_in_phenylalanine-accepting_tRNA YML006C GIS4 None intracellular_signaling_cascade molecular_function_unknown cytoplasm None None 13 258416 256092 YML006C S000004465 "ORF,_Verified" "CAAX_box_containing_protein_of_unknown_function,_proposed_to_be_involved_in_the_RAS/cAMP_signaling_pathway" YML007W YAP1 SNQ3|PAR1 response_to_oxidative_stress* transcription_factor_activity cytoplasm* None Up 13 253848 255800 YML007W S000004466 "ORF,_Verified" Basic_leucine_zipper_(bZIP)_transcription_factor_required_for_oxidative_stress_tolerance;_activated_by_H2O2_through_the_multistep_formation_of_disulfide_bonds_and_transit_from_the_cytoplasm_to_the_nucleus;_mediates_resistance_to_cadmium YML008C ERG6 VID1|SED6|LIS1|ISE1 ergosterol_biosynthesis sterol_24-C-methyltransferase_activity mitochondrion* None None 13 252990 251839 YML008C S000004467 "ORF,_Verified" "Delta(24)-sterol_C-methyltransferase,_converts_zymosterol_to_fecosterol_in_the_ergosterol_biosynthetic_pathway_by_methylating_position_C-24;_localized_to_both_lipid_particles_and_mitochondrial_outer_membrane" YML009C MRPL39 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 13 251516 251304 YML009C S000004468 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YML010W SPT5 None "regulation_of_transcription,_DNA-dependent*" RNA_polymerase_II_transcription_elongation_factor_activity nucleus* None None 13 247677 250868 YML010W S000004470 "ORF,_Verified" Protein_that_forms_a_complex_with_Spt4p_and_mediates_both_activation_and_inhibition_of_transcription_elongation;_Spt4p-Spt5p_complex_also_plays_a_role_in_pre-mRNA_processing YML011C RAD33 None biological_process_unknown molecular_function_unknown nucleus None None 13 247428 246895 YML011C S000004472 "ORF,_Verified" Protein_involved_in_nucleotide_excision_repair;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus YML012W ERV25 None ER_to_Golgi_transport molecular_function_unknown COPII-coated_vesicle S None 13 246116 246751 YML012W S000004473 "ORF,_Verified" "Protein_that_forms_a_heterotrimeric_complex_with_Erp1,_Erp2p,_and_Emp24,_member_of_the_p24_family_involved_in_endoplasmic_reticulum_to_Golgi_transport" YML013W UBX2 SEL1 protein_secretion* molecular_function_unknown endoplasmic_reticulum None Up 13 244149 245903 YML013W S000004475 "ORF,_Verified" Protein_involved_in_ER-associated_protein_degradation;_proposed_to_coordinate_the_assembly_of_proteins_involved_in_ERAD;_contains_a_UBX_(ubiquitin_regulatory_X)_domain_and_a_ubiquitin-associated_(UBA)_domain YML014W TRM9 KTI1 response_to_stress* tRNA_(uridine)_methyltransferase_activity cytoplasm* None None 13 243225 244064 YML014W S000004476 "ORF,_Verified" "tRNA_methyltransferase,_catalyzes_esterification_of_modified_uridine_nucleotides_in_tRNA(Arg3)_and_tRNA(Glu),_likely_as_part_of_a_complex_with_Trm112p;_deletion_confers_resistance_to_zymocin" YML015C TAF11 TAF40 transcription_initiation_from_RNA_polymerase_II_promoter* general_RNA_polymerase_II_transcription_factor_activity transcription_factor_TFIID_complex None None 13 243029 241989 YML015C S000004477 "ORF,_Verified" "TFIID_subunit_(40_kDa),_involved_in_RNA_polymerase_II_transcription_initiation,_similar_to_histone_H3_with_atypical_histone_fold_motif_of_Spt3-like_transcription_factors" YML016C PPZ1 None sodium_ion_homeostasis protein_serine/threonine_phosphatase_activity cytoplasm* None None 13 241536 239458 YML016C S000004478 "ORF,_Verified" "Serine/threonine_protein_phosphatase_Z,_isoform_of_Ppz2p;_involved_in_regulation_of_potassium_transport,_which_affects_osmotic_stability,_cell_cycle_progression,_and_halotolerance" YML017W PSP2 MRS15 biological_process_unknown molecular_function_unknown cytoplasm None None 13 236588 238731 YML017W S000004479 "ORF,_Verified" Asn_rich_cytoplasmic_protein_that_contains_RGG_motifs;_high-copy_suppressor_of_group_II_intron-splicing_defects_of_a_mutation_in_MRS2_and_of_a_conditional_mutation_in_POL1_(DNA_polymerase_alpha);_possible_role_in_mitochondrial_mRNA_splicing YML018C None None biological_process_unknown molecular_function_unknown vacuolar_membrane_(sensu_Fungi) None None 13 235952 234771 YML018C S000004480 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_membrane_of_the_vacuole;_physical_interaction_with_Atg27p_suggests_a_possible_role_in_autophagy;_YML018C_is_not_an_essential_gene YML019W OST6 None protein_complex_assembly* dolichyl-diphosphooligosaccharide-protein_glycotransferase_activity oligosaccharyl_transferase_complex None None 13 233457 234455 YML019W S000004481 "ORF,_Verified" "Subunit_of_the_oligosaccharyltransferase_complex_of_the_ER_lumen,_which_catalyzes_asparagine-linked_glycosylation_of_newly_synthesized_proteins;_similar_to_and_partially_functionally_redundant_with_Ost3p" YML020W None None biological_process_unknown molecular_function_unknown cellular_component_unknown G1 None 13 231149 233143 YML020W S000004482 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YML021C UNG1 None DNA_repair uracil_DNA_N-glycosylase_activity nucleus* G1 None 13 230813 229734 YML021C S000004483 "ORF,_Verified" "Uracil-DNA_glycosylase,_required_for_repair_of_uracil_in_DNA_formed_by_spontaneous_cytosine_deamination,_not_required_for_strand-specific_mismatch_repair,_cell-cycle_regulated,_expressed_in_late_G1,_localizes_to_mitochondria_and_nucleus" YML022W APT1 None AMP_biosynthesis* adenine_phosphoribosyltransferase_activity cytoplasm* None None 13 228937 229500 YML022W S000004484 "ORF,_Verified" "Adenine_phosphoribosyltransferase,_catalyzes_the_formation_of_AMP_from_adenine_and_5-phosphoribosylpyrophosphate;_involved_in_the_salvage_pathway_of_purine_nucleotide_biosynthesis" YML023C NSE5 None DNA_repair molecular_function_unknown nucleus None None 13 228664 226994 YML023C S000004485 "ORF,_Verified" Essential_subunit_of_the_Mms21-Smc5-Smc6_complex;_required_for_cell_viability_and_DNA_repair YML024W RPS17A RPL51A|RP51A protein_biosynthesis* structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota)* None None 13 225889 226697 YML024W S000004486 "ORF,_Verified" Ribosomal_protein_51_(rp51)_of_the_small_(40s)_subunit;_nearly_identical_to_Rps17Bp_and_has_similarity_to_rat_S17_ribosomal_protein YML025C YML6 None protein_biosynthesis* structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 13 225365 224406 YML025C S000004487 "ORF,_Verified" "Mitochondrial_ribosomal_protein_of_the_large_subunit,_has_similarity_to_E._coli_L4_ribosomal_protein_and_human_mitoribosomal_MRP-L4_protein;_essential_for_viability,_unlike_most_other_mitoribosomal_proteins" YML026C RPS18B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None Down 13 223828 222987 YML026C S000004488 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_nearly_identical_to_Rps18Ap_and_has_similarity_to_E._coli_S13_and_rat_S18_ribosomal_proteins YML027W YOX1 None negative_regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus G1 None 13 221406 222563 YML027W S000004489 "ORF,_Verified" "Homeodomain-containing_transcriptional_repressor,_binds_to_Mcm1p_and_to_early_cell_cycle_boxes_(ECBs)_in_the_promoters_of_cell_cycle-regulated_genes_expressed_in_M/G1_phase;_expression_is_cell_cycle-regulated;_potential_Cdc28p_substrate" YML028W TSA1 TPX1|ZRG14 response_to_oxidative_stress* thioredoxin_peroxidase_activity cytoplasm None None 13 220138 220728 YML028W S000004490 "ORF,_Verified" "Thioredoxin_peroxidase,_acts_as_both_a_ribosome-associated_and_free_cytoplasmic_antioxidant;_self-associates_to_form_a_high-molecular_weight_chaperone_complex_under_oxidative_stress;_deletion_results_in_mutator_phenotype" YML029W USA1 None "nuclear_mRNA_splicing,_via_spliceosome" molecular_function_unknown cellular_component_unknown None None 13 217362 219878 YML029W S000004491 "ORF,_Verified" "Protein_involved_in_ER-associated_protein_degradation_(ERAD);_component_of_the_Hrd1p_complex;_interacts_with_the_U1_snRNP-specific_protein,_Snp1p" YML030W None None biological_process_unknown molecular_function_unknown mitochondrion None None 13 216435 216914 YML030W S000004492 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_GFP-fusion_protein_localizes_to_mitochondria;_null_mutant_is_viable_and_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation)_and_severe_growth_rate_in_minimal_glycerol_media YML032C RAD52 None telomerase-independent_telomere_maintenance* recombinase_activity* nucleus* None None 13 213930 212515 YML032C S000004494 "ORF,_Verified" Protein_that_stimulates_strand_exchange_by_facilitating_Rad51p_binding_to_single-stranded_DNA;_anneals_complementary_single-stranded_DNA;_involved_in_the_repair_of_double-strand_breaks_in_DNA_during_vegetative_growth_and_meiosis YML034W SRC1 HEH1|YML033W mitotic_sister_chromatid_segregation molecular_function_unknown cellular_component_unknown G2/M None 13 209525 212155 YML034W S000004497 "ORF,_Verified" "Inner_nuclear_membrane_(INM)_protein_with_a_putative_role_in_sister_chromatid_segregation,_potentially_phosphorylated_by_Cdc28p;_contains_helix-extension-helix_(HEH)_motif,_nuclear_localization_signal_sequence" YML035C AMD1 AMD3 purine_nucleotide_metabolism AMP_deaminase_activity cytoplasm None None 13 208860 206428 YML035C S000004498 "ORF,_Verified" "AMP_deaminase,_tetrameric_enzyme_that_catalyzes_the_deamination_of_AMP_to_form_IMP_and_ammonia;_may_be_involved_in_regulation_of_intracellular_adenine_nucleotide_pools" YML037C None None biological_process_unknown molecular_function_unknown clathrin-coated_vesicle None None 13 205408 204386 YML037C S000004501 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_some_characteristics_of_a_transcriptional_activator;_may_be_a_target_of_Dbf2p-Mob1p_kinase;_GFP-fusion_protein_co-localizes_with_clathrin-coated_vesicles;_YML037C_is_not_an_essential_gene YML038C YMD8 None nucleotide-sugar_transport nucleotide-sugar_transporter_activity COPI-coated_vesicle None None 13 204103 202775 YML038C S000004502 "ORF,_Verified" "Putative_nucleotide_sugar_transporter,_has_similarity_to_Vrg4p" YML039W None None None None None None None 13 196628 201896 YML039W S000004503 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YML040W None None None None None None None 13 196628 197950 YML040W S000004504 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YML041C VPS71 SWC6 protein_targeting_to_vacuole* molecular_function_unknown nucleus* None None 13 195755 194913 YML041C S000004505 "ORF,_Verified" "Nucleosome-binding_component_of_the_SWR1_complex,_which_exchanges_histone_variant_H2AZ_(Htz1p)_for_chromatin-bound_histone_H2A;_required_for_vacuolar_protein_sorting" YML042W CAT2 YCAT carnitine_metabolism carnitine_O-acetyltransferase_activity mitochondrion* None None 13 192788 194800 YML042W S000004506 "ORF,_Verified" "Carnitine_acetyl-CoA_transferase_present_in_both_mitochondria_and_peroxisomes,_transfers_activated_acetyl_groups_to_carnitine_to_form_acetylcarnitine_which_can_be_shuttled_across_membranes" YML045W None None None None None None None 13 184461 189729 YML045W S000004508 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YML045W-A None None None None None None None 13 184461 185783 YML045W-A S000007381 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YML046W PRP39 None nuclear_mRNA_5'-splice_site_recognition "RNA_splicing_factor_activity,_transesterification_mechanism*" snRNP_U1* None None 13 181474 183363 YML046W S000004509 "ORF,_Verified" "U1_snRNP_protein_involved_in_splicing,_contains_multiple_tetriatricopeptide_repeats" YML049C RSE1 None "nuclear_mRNA_splicing,_via_spliceosome*" U2_snRNA_binding snRNP_U2 None None 13 178305 174220 YML049C S000004513 "ORF,_Verified" Protein_involved_in_pre-mRNA_splicing;_component_of_the_pre-spliceosome;_associates_with_U2_snRNA;_involved_in_ER_to_Golgi_transport YML050W None None biological_process_unknown molecular_function_unknown cellular_component_unknown G2/M None 13 173139 174074 YML050W S000004514 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_non-essential_gene;_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss_(petite_formation) YML051W GAL80 None "regulation_of_transcription,_DNA-dependent*" transcription_corepressor_activity cytoplasm* None None 13 171594 172901 YML051W S000004515 "ORF,_Verified" Transcriptional_regulator_involved_in_the_repression_of_GAL_genes_in_the_absence_of_galactose;_inhibits_transcriptional_activation_by_Gal4p;_inhibition_relieved_by_Gal3p_or_Gal1p_binding YML052W SUR7 None sporulation_(sensu_Fungi) molecular_function_unknown mitochondrion* G2/M None 13 170402 171310 YML052W S000004516 "ORF,_Verified" "Putative_integral_membrane_protein;_component_of_eisosomes;_associated_with_endocytosis,_along_with_Pil1p_and_Lsp1p;_sporulation_and_plasma_membrane_sphingolipid_content_are_altered_in_mutants" YML054C CYB2 None electron_transport L-lactate_dehydrogenase_(cytochrome)_activity mitochondrial_intermembrane_space None None 13 167308 165533 YML054C S000004518 "ORF,_Verified" "Cytochrome_b2_(L-lactate_cytochrome-c_oxidoreductase),_component_of_the_mitochondrial_intermembrane_space,_required_for_lactate_utilization;_expression_is_repressed_by_glucose_and_anaerobic_conditions" YML055W SPC2 SPY1 signal_peptide_processing protein_binding signal_peptidase_complex None None 13 164790 165326 YML055W S000004519 "ORF,_Verified" "Subunit_of_signal_peptidase_complex_(Spc1p,_Spc2p,_Spc3p,_Sec11p),_which_catalyzes_cleavage_of_N-terminal_signal_sequences_of_proteins_targeted_to_the_secretory_pathway;_homologous_to_mammalian_SPC25" YML056C IMD4 None biological_process_unknown IMP_dehydrogenase_activity cytoplasm None Down 13 164176 162194 YML056C S000004520 "ORF,_Verified" "Inosine_monophosphate_dehydrogenase,_catalyzes_the_first_step_of_GMP_biosynthesis,_member_of_a_four-gene_family_in_S._cerevisiae,_constitutively_expressed" YML057W CMP2 CNA2 cell_ion_homeostasis* calcium-dependent_protein_serine/threonine_phosphatase_activity cytoplasm* None None 13 160180 161994 YML057W S000004521 "ORF,_Verified" "Calcineurin_A;_one_isoform_(the_other_is_CNA1)_of_the_catalytic_subunit_of_calcineurin,_a_Ca++/calmodulin-regulated_protein_phosphatase_which_regulates_Crz1p_(a_stress-response_transcription_factor),_the_other_calcineurin_subunit_is_CNB1" YML058W SML1 None mitochondrion_organization_and_biogenesis* enzyme_inhibitor_activity cytoplasm* S/G2 None 13 159383 159697 YML058W S000004523 "ORF,_Verified" Ribonucleotide_reductase_inhibitor_involved_in_regulating_dNTP_production;_regulated_by_Mec1p_and_Rad53p_during_DNA_damage_and_S_phase YML058W-A HUG1 None response_to_DNA_damage_stimulus* molecular_function_unknown cytoplasm None None 13 158760 158966 YML058W-A S000007472 "ORF,_Verified" "Protein_involved_in_the_Mec1p-mediated_checkpoint_pathway_that_responds_to_DNA_damage_or_replication_arrest,_transcription_is_induced_by_DNA_damage" YML059C NTE1 None phosphatidylcholine_metabolism hydrolase_activity* endoplasmic_reticulum None None 13 158258 153219 YML059C S000004524 "ORF,_Verified" "Serine_esterase_that_deacylates_exogenous_lysophospholipids,_homolog_of_human_neuropathy_target_esterase_(NTE);_mammalian_NTE1_deacylates_phosphatidylcholine_to_glycerophosphocholine" YML060W OGG1 None DNA_repair* purine-specific_oxidized_base_lesion_DNA_N-glycosylase_activity mitochondrion G1 None 13 151871 153001 YML060W S000004525 "ORF,_Verified" "Mitochondrial_glycosylase/lyase_that_specifically_excises_7,8-dihydro-8-oxoguanine_residues_located_opposite_cytosine_or_thymine_residues_in_DNA,_repairs_oxidative_damage_to_mitochondrial_DNA" YML061C PIF1 TST1 mitochondrial_genome_maintenance* DNA_helicase_activity nucleus* G1 None 13 151532 148953 YML061C S000004526 "ORF,_Verified" DNA_helicase_involved_in_telomere_formation_and_elongation;_acts_as_a_catalytic_inhibitor_of_telomerase;_also_plays_a_role_in_repair_and_recombination_of_mitochondrial_DNA YML062C MFT1 MFT52 mRNA_export_from_nucleus* nucleic_acid_binding THO_complex None Up 13 148683 147505 YML062C S000004527 "ORF,_Verified" "Subunit_of_the_THO_complex,_which_is_a_nuclear_complex_comprised_of_Hpr1p,_Mft1p,_Rlr1p,_and_Thp2p,_that_is_involved_in_transcription_elongation_and_mitotic_recombination;_involved_in_telomere_maintenance" YML063W RPS1B RP10B|PLC2 protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 13 146482 147249 YML063W S000004528 "ORF,_Verified" Ribosomal_protein_10_(rp10)_of_the_small_(40S)_subunit;_nearly_identical_to_Rps1Ap_and_has_similarity_to_rat_S3a_ribosomal_protein YML064C TEM1 None signal_transduction* protein_binding* spindle_pole_body G2/M None 13 145876 145139 YML064C S000004529 "ORF,_Verified" GTP-binding_protein_of_the_ras_superfamily_involved_in_termination_of_M-phase;_controls_actomyosin_and_septin_dynamics_during_cytokinesis YML065W ORC1 None DNA_replication_initiation* ATPase_activity* pre-replicative_complex* S/G2 None 13 142210 144954 YML065W S000004530 "ORF,_Verified" "Largest_subunit_of_the_origin_recognition_complex,_which_directs_DNA_replication_by_binding_to_replication_origins_and_is_also_involved_in_transcriptional_silencing;_exhibits_ATPase_activity" YML067C ERV41 None ER_to_Golgi_transport molecular_function_unknown integral_to_endoplasmic_reticulum_membrane* None None 13 140214 139063 YML067C S000004532 "ORF,_Verified" "Protein_localized_to_COPII-coated_vesicles,_forms_a_complex_with_Erv46p;_involved_in_the_membrane_fusion_stage_of_transport;_has_homology_to_human_ERGIC2_(PTX1)_protein" YML068W ITT1 None regulation_of_translational_termination molecular_function_unknown cellular_component_unknown None None 13 137550 138944 YML068W S000004533 "ORF,_Verified" "Protein_that_modulates_the_efficiency_of_translation_termination,_interacts_with_translation_release_factors_eRF1_(Sup45p)_and_eRF3_(Sup35p)_in_vitro,_contains_a_zinc_finger_domain_characteristic_of_the_TRIAD_class_of_proteins" YML069W POB3 None chromatin_remodeling* chromatin_binding nucleus* None None 13 135500 137158 YML069W S000004534 "ORF,_Verified" "Subunit_of_the_heterodimeric_FACT_complex_(Spt16p-Pob3p),_which_facilitates_RNA_Pol_II_transcription_elongation_through_nucleosomes_by_destabilizing_and_then_reassembling_nucleosome_structure;_interacts_with_DNA_polymerase_alpha_(Pol1p)" YML070W DAK1 None response_to_stress* glycerone_kinase_activity cytoplasm None Up 13 133475 135229 YML070W S000004535 "ORF,_Verified" "Dihydroxyacetone_kinase,_required_for_detoxification_of_dihydroxyacetone_(DHA);_involved_in_stress_adaptation" YML071C COG8 DOR1 intra-Golgi_transport molecular_function_unknown Golgi_transport_complex None None 13 131572 129749 YML071C S000004536 "ORF,_Verified" "Component_of_the_conserved_oligomeric_Golgi_complex_(Cog1p_through_Cog8p),_a_cytosolic_tethering_complex_that_functions_in_protein_trafficking_to_mediate_fusion_of_transport_vesicles_to_Golgi_compartments" YML072C TCB3 None biological_process_unknown lipid_binding mitochondrion* S/G2 None 13 129367 124730 YML072C S000004537 "ORF,_Verified" "Lipid-binding_protein,_localized_to_the_bud_via_specific_mRNA_transport;_non-tagged_protein_detected_in_a_phosphorylated_state_in_mitochondria;_GFP-fusion_protein_localizes_to_the_cell_periphery;_C-termini_of_Tcb1p,_Tcb2p_and_Tcb3p_interact" YML073C RPL6A YL16A protein_biosynthesis* structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 13 124172 123227 YML073C S000004538 "ORF,_Verified" "N-terminally_acetylated_protein_component_of_the_large_(60S)_ribosomal_subunit,_has_similarity_to_Rpl6Bp_and_to_rat_L6_ribosomal_protein;_binds_to_5.8S_rRNA" YML074C FPR3 NPI46 biological_process_unknown peptidyl-prolyl_cis-trans_isomerase_activity nucleolus None None 13 121324 120089 YML074C S000004539 "ORF,_Verified" Nucleolar_peptidyl-prolyl_cis-trans_isomerase_(PPIase);_FK506_binding_protein;_phosphorylated_by_casein_kinase_II_(Cka1p-Cka2p-Ckb1p-Ckb2p)_and_dephosphorylated_by_Ptp1p YML076C WAR1 None response_to_acid transcription_factor_activity nucleus* None None 13 115347 112513 YML076C S000004541 "ORF,_Verified" "Homodimeric_Zn2Cys6_zinc_finger_transcription_factor;_binds_to_a_weak_acid_response_element_to_induce_transcription_of_PDR12_and_FUN34,_encoding_an_acid_transporter_and_a_putative_ammonia_transporter,_respectively" YML077W BET5 None ER_to_Golgi_transport molecular_function_unknown TRAPP_complex None None 13 111865 112344 YML077W S000004542 "ORF,_Verified" "Component_of_the_TRAPP_(transport_protein_particle)_complex,_which_plays_an_essential_role_in_the_vesicular_transport_from_endoplasmic_reticulum_to_Golgi" YML079W None None biological_process_unknown molecular_function_unknown cytoplasm* None None 13 110247 110852 YML079W S000004544 "ORF,_Uncharacterized" "Non-essential_protein_of_unknown_function_with_structural_resemblance_to_plant_storage_and_ligand_binding_proteins_(canavalin,_glycinin,_auxin_binding_protein)_and_to_some_enzymes_(epimerase,_germin);_localizes_to_the_nucleus_and_cytoplasm" YML080W DUS1 None tRNA_modification tRNA_dihydrouridine_synthase_activity nucleus None None 13 108806 110077 YML080W S000004545 "ORF,_Verified" "Dihydrouridine_synthase,_member_of_a_widespread_family_of_conserved_proteins_including_Smm1p,_Dus3p,_and_Dus4p;_modifies_pre-tRNA(Phe)_at_U17" YML081W None None biological_process_unknown molecular_function_unknown nucleus None None 13 104777 108532 YML081W S000004546 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus;_YML081w_is_not_an_essential_gene YML082W None None sulfur_metabolism carbon-sulfur_lyase_activity cytoplasm* None None 13 101862 103811 YML082W S000004547 "ORF,_Uncharacterized" Putative_protein_predicted_to_have_carbon-sulfur_lyase_activity;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus_and_the_cytoplasm;_YNML082W_is_not_an_essential_gene YML085C TUB1 None mitotic_sister_chromatid_segregation* structural_constituent_of_cytoskeleton spindle_pole_body* None None 13 99400 97941 YML085C S000004550 "ORF,_Verified" "Alpha-tubulin;_associates_with_beta-tubulin_(Tub2p)_to_form_tubulin_dimer,_which_polymerizes_to_form_microtubules" YML086C ALO1 None response_to_oxidative_stress "D-arabinono-1,4-lactone_oxidase_activity" mitochondrion None None 13 97371 95791 YML086C S000004551 "ORF,_Verified" "D-Arabinono-1,4-lactone_oxidase,_catalyzes_the_final_step_in_biosynthesis_of_D-erythroascorbic_acid,_which_is_protective_against_oxidative_stress" YML087C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 95369 94431 YML087C S000004552 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_highly_conserved_across_species_and_orthologous_to_human_CYB5R4;_null_mutant_shows_increased_frequency_of_mitochondrial_genome_loss_(petite_formation)_and_severe_growth_defect_in_minimal_glycerol_media YML088W UFO1 None ubiquitin-dependent_protein_catabolism* protein_binding* cytoplasm* None Up 13 92235 94241 YML088W S000004553 "ORF,_Verified" "F-box_receptor_protein,_subunit_of_the_Skp1-Cdc53-F-box_receptor_(SCF)_E3_ubiquitin_ligase_complex;_binds_to_phosphorylated_Ho_endonuclease,_allowing_its_ubiquitylation_by_SCF_and_subsequent_degradation" YML091C RPM2 None protein_biosynthesis* ribonuclease_P_activity mitochondrion None None 13 90731 87123 YML091C S000004556 "ORF,_Verified" "Protein_subunit_of_mitochondrial_RNase_P,_has_roles_in_nuclear_transcription,_cytoplasmic_and_mitochondrial_RNA_processing,_and_mitochondrial_translation;_distributed_to_mitochondria,_cytoplasmic_processing_bodies,_and_the_nucleus" YML093W UTP14 None processing_of_20S_pre-rRNA snoRNA_binding small_nucleolar_ribonucleoprotein_complex None None 13 83090 85789 YML093W S000004558 "ORF,_Verified" Subunit_of_U3-containing_Small_Subunit_(SSU)_processome_complex_involved_in_production_of_18S_rRNA_and_assembly_of_small_ribosomal_subunit YML094W GIM5 PFD5 tubulin_folding tubulin_binding cytoplasm* None None 13 82275 82849 YML094W S000004559 "ORF,_Verified" Subunit_of_the_heterohexameric_cochaperone_prefoldin_complex_which_binds_specifically_to_cytosolic_chaperonin_and_transfers_target_proteins_to_it YML095C RAD10 None removal_of_nonhomologous_ends* single-stranded_DNA_specific_endodeoxyribonuclease_activity nucleotide-excision_repair_factor_1_complex None None 13 82113 81481 YML095C S000004560 "ORF,_Verified" "Single-stranded_DNA_endonuclease_(with_Rad1p),_cleaves_single-stranded_DNA_during_nucleotide_excision_repair_and_double-strand_break_repair;_subunit_of_Nucleotide_Excision_Repair_Factor_1_(NEF1);_homolog_of_human_ERCC1_protein" YML096W None None biological_process_unknown molecular_function_unknown cytoplasm None None 13 79909 81486 YML096W S000004562 "ORF,_Uncharacterized" Putative_protein_of_unknown_function_with_similarity_to_asparagine_synthetases;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YML096W_is_not_an_essential_gene_and_partially_overlaps_the_verified_gene_RAD10 YML097C VPS9 VPT9|VPL31 protein_targeting_to_vacuole guanyl-nucleotide_exchange_factor_activity cytosol None None 13 79690 78335 YML097C S000004563 "ORF,_Verified" A_guanine_nucleotide_exchange_factor_involved_in_vesicle-mediated_vacuolar_protein_transport;_specifically_stimulates_the_intrinsic_guanine_nucleotide_exchange_activity_of_Vps21p/Rab5:_similar_to_mammalian_ras_inhibitors;_binds_ubiquitin YML098W TAF13 TAF19|FUN81 transcription_initiation_from_RNA_polymerase_II_promoter* general_RNA_polymerase_II_transcription_factor_activity nucleus* None None 13 77267 77770 YML098W S000004564 "ORF,_Verified" "TFIID_subunit_(19_kDa),_involved_in_RNA_polymerase_II_transcription_initiation,_similar_to_histone_H4_with_atypical_histone_fold_motif_of_Spt3-like_transcription_factors" YML099C ARG81 ARGRII|ARGR2 arginine_metabolism* transcription_cofactor_activity nucleus None None 13 77040 74398 YML099C S000004565 "ORF,_Verified" "Zinc-finger_transcription_factor_of_the_Zn(2)-Cys(6)_binuclear_cluster_domain_type,_involved_in_the_regulation_of_arginine-responsive_genes;_acts_with_Arg80p_and_Arg82p" YML100W TSL1 None response_to_stress* enzyme_regulator_activity* "alpha,alpha-trehalose-phosphate_synthase_complex_(UDP-forming)" G1 None 13 70624 73920 YML100W S000004566 "ORF,_Verified" "Large_subunit_of_trehalose_6-phosphate_synthase_(Tps1p)/phosphatase_(Tps2p)_complex,_which_converts_uridine-5'-diphosphoglucose_and_glucose_6-phosphate_to_trehalose,_homologous_to_Tps3p_and_may_share_function" YML100W-A None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 70138 70311 YML100W-A S000028688 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function;_identified_by_gene-trapping,_microarray-based_expression_analysis,_and_genome-wide_homology_searching" YML101C CUE4 None biological_process_unknown molecular_function_unknown cytoplasm* None None 13 70088 69735 YML101C S000004568 "ORF,_Verified" "Protein_of_unknown_function;_has_a_CUE_domain_that_binds_ubiquitin,_which_may_facilitate_intramolecular_monoubiquitination" YML102W CAC2 None DNA_repair* transcription_regulator_activity chromatin_assembly_complex* G1 None 13 68294 69700 YML102W S000004570 "ORF,_Verified" "Component_of_the_chromatin_assembly_complex_(with_Rlf2p_and_Msi1p)_that_assembles_newly_synthesized_histones_onto_recently_replicated_DNA,_required_for_building_functional_kinetochores,_conserved_from_yeast_to_humans" YML103C NUP188 None mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 13 67549 62582 YML103C S000004571 "ORF,_Verified" "Subunit_of_the_nuclear_pore_complex_(NPC),_involved_in_the_structural_organization_of_the_complex_and_of_the_nuclear_envelope,_also_involved_in_nuclear_envelope_permeability,_interacts_with_Pom152p_and_Nic96p" YML104C MDM1 None mitochondrion_organization_and_biogenesis* structural_constituent_of_cytoskeleton cytoplasm* None None 13 62322 58939 YML104C S000004572 "ORF,_Verified" "Intermediate_filament_protein,_required_for_nuclear_and_mitochondrial_transmission_to_daughter_buds;_contains_a_Phox_homology_(PX)_domain_and_specifically_binds_phosphatidylinositol_3-phosphate_(PtdIns-3-P)" YML105C SEC65 None protein_targeting_to_ER* molecular_function_unknown signal_recognition_particle_(sensu_Eukaryota) None None 13 58687 57866 YML105C S000004573 "ORF,_Verified" "Subunit_of_the_signal_recognition_particle_(SRP),_involved_in_protein_targeting_to_the_ER;_interacts_with_Srp54p;_homolog_of_mammalian_SRP19" YML106W URA5 PYR5 de_novo'_pyrimidine_base_biosynthesis orotate_phosphoribosyltransferase_activity cytoplasm* None None 13 56773 57453 YML106W S000004574 "ORF,_Verified" "Major_orotate_phosphoribosyltransferase_(OPRTase)_isozyme_that_catalyzes_the_fifth_enzymatic_step_in_de_novo_biosynthesis_of_pyrimidines,_converting_orotate_into_orotidine-5'-phosphate;_minor_OPRTase_encoded_by_URA10" YML107C PML39 None mRNA_export_from_nucleus molecular_function_unknown nuclear_pore None None 13 56269 55265 YML107C S000004575 "ORF,_Verified" Protein_required_for_nuclear_retention_of_unspliced_pre-mRNAs_along_with_Mlp1p_and_Pml1p;_anchored_to_nuclear_pore_complex_via_Mlp1p_and_Mlp2p;_found_with_the_subset_of_nuclear_pores_farthest_from_the_nucleolus;_may_interact_with_ribosomes YML109W ZDS2 CES4 establishment_of_cell_polarity_(sensu_Fungi)* molecular_function_unknown nucleus G1 None 13 51640 54468 YML109W S000004577 "ORF,_Verified" "Protein_that_interacts_with_silencing_proteins_at_the_telomere,_involved_in_transcriptional_silencing;_paralog_of_Zds1p" YML110C COQ5 DBI56 aerobic_respiration* "2-hexaprenyl-6-methoxy-1,4-benzoquinone_methyltransferase_activity" mitochondrion M/G1 None 13 50954 50031 YML110C S000004578 "ORF,_Verified" "2-hexaprenyl-6-methoxy-1,4-benzoquinone_methyltransferase,_involved_in_ubiquinone_(Coenzyme_Q)_biosynthesis;_localizes_to_the_matrix_face_of_the_mitochondrial_inner_membrane_in_a_large_complex_with_other_ubiquinone_biosynthetic_enzymes" YML111W BUL2 None protein_monoubiquitination* protein_binding cytoplasm* None None 13 46942 49704 YML111W S000004579 "ORF,_Verified" "Component_of_the_Rsp5p_E3-ubiquitin_ligase_complex,_involved_in_intracellular_amino_acid_permease_sorting,_functions_in_heat_shock_element_mediated_gene_expression,_essential_for_growth_in_stress_conditions,_functional_homolog_of_BUL1" YML112W CTK3 None protein_amino_acid_phosphorylation* cyclin-dependent_protein_kinase_activity nucleus None Up 13 45063 45953 YML112W S000004580 "ORF,_Verified" "Gamma_subunit_of_C-terminal_domain_kinase_I_(CTDK-I),_which_phosphorylates_both_RNA_pol_II_subunit_Rpo21p_to_affect_transcription_and_pre-mRNA_3'_end_processing,_and_ribosomal_protein_Rps2p_to_increase_translational_fidelity" YML113W DAT1 None negative_regulation_of_transcription_from_RNA_polymerase_II_promoter AT_DNA_binding nucleus None None 13 44045 44791 YML113W S000004581 "ORF,_Verified" DNA_binding_protein_that_recognizes_oligo(dA).oligo(dT)_tracts;_Arg_side_chain_in_its_N-terminal_pentad_Gly-Arg-Lys-Pro-Gly_repeat_is_required_for_DNA-binding;_not_essential_for_viability YML114C TAF8 TAF65 transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_factor_activity nucleus* None None 13 43575 42043 YML114C S000004582 "ORF,_Verified" "TFIID_subunit_(65_kDa),_involved_in_RNA_polymerase_II_transcription_initiation" YML115C VAN1 LDB13|VRG8|VRG7 protein_amino_acid_N-linked_glycosylation mannosyltransferase_activity membrane* None None 13 41794 40187 YML115C S000004583 "ORF,_Verified" "Component_of_the_mannan_polymerase_I,_which_contains_Van1p_and_Mnn9p_and_is_involved_in_the_first_steps_of_mannan_synthesis;_mutants_are_vanadate-resistant" YML116W ATR1 SNQ1 multidrug_transport multidrug_efflux_pump_activity plasma_membrane G2/M Up 13 38196 39824 YML116W S000004584 "ORF,_Verified" "Multidrug_efflux_pump_of_the_major_facilitator_superfamily,_required_for_resistance_to_aminotriazole_and_4-nitroquinoline-N-oxide" YML117W NAB6 None biological_process_unknown RNA_binding cytoplasm S None 13 34243 37647 YML117W S000004585 "ORF,_Verified" "Putative_RNA-binding_protein,_based_on_computational_analysis_of_large-scale_protein-protein_interaction_data" YML118W NGL3 None biological_process_unknown endonuclease_activity cellular_component_unknown None None 13 32334 33851 YML118W S000004587 "ORF,_Verified" "Putative_endonuclease,_has_a_domain_similar_to_a_magnesium-dependent_endonuclease_motif_in_mRNA_deadenylase_Ccr4p;_similar_to_Ngl1p_and_Ngl2p" YML119W None None biological_process_unknown molecular_function_unknown cellular_component_unknown G2/M None 13 30611 31684 YML119W S000004588 "ORF,_Uncharacterized" Putative_protein_of_unknown_funtion;_YML119W_is_not_an_essential_gene;_potential_Cdc28p_substrate YML120C NDI1 None "mitochondrial_electron_transport,_NADH_to_ubiquinone" "oxidoreductase_activity,_acting_on_NADH_or_NADPH,_quinone_or_similar_compound_as_acceptor" mitochondrial_inner_membrane G2/M None 13 29807 28266 YML120C S000004589 "ORF,_Verified" "NADH:ubiquinone_oxidoreductase,_transfers_electrons_from_NADH_to_ubiquinone_in_the_respiratory_chain_but_does_not_pump_protons,_in_contrast_to_the_higher_eukaryotic_multisubunit_respiratory_complex_I;_phosphorylated;_homolog_of_human_AMID" YML121W GTR1 None phosphate_transport GTPase_activity cytoplasm* None None 13 26930 27862 YML121W S000004590 "ORF,_Verified" "Cytoplasmic_GTP_binding_protein_and_negative_regulator_of_the_Ran/Tc4_GTPase_cycle;_component_of_GSE_complex,_which_is_required_for_sorting_of_Gap1p;_involved_in_phosphate_transport_and_telomeric_silencing;_similar_to_human_RagA_and_RagB" YML123C PHO84 phoT phosphate_transport* manganese_ion_transporter_activity* integral_to_plasma_membrane G2/M Down 13 25801 24038 YML123C S000004592 "ORF,_Verified" High-affinity_inorganic_phosphate_(Pi)_transporter_and_low-affinity_manganese_transporter;_regulated_by_Pho4p_and_Spt7p;_mutation_confers_resistance_to_arsenate;_exit_from_the_ER_during_maturation_requires_Pho86p YML125C PGA3 None biological_process_unknown molecular_function_unknown endoplasmic_reticulum S/G2 None 13 21700 20762 YML125C S000004594 "ORF,_Verified" "Essential_protein_required_for_maturation_of_Gas1p_and_Pho8p,_proposed_to_be_involved_in_protein_trafficking;_GFP-fusion_protein_localizes_to_the_endoplasmic_reticulum;_null_mutants_have_a_cell_separation_defect" YML128C MSC1 None meiotic_recombination molecular_function_unknown mitochondrion* None Up 13 16677 15136 YML128C S000004597 "ORF,_Verified" "Protein_of_unknown_function;_mutant_is_defective_in_directing_meiotic_recombination_events_to_homologous_chromatids;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_and_is_phosphorylated" YML129C COX14 None aerobic_respiration* molecular_function_unknown integral_to_membrane* None None 13 14754 14542 YML129C S000004598 "ORF,_Verified" "Mitochondrial_membrane_protein,_involved_in_translational_regulation_of_Cox1p_and_assembly_of_cytochrome_c_oxidase_(complex_IV);_associates_with_complex_IV_assembly_intermediates_and_complex_III/complex_IV_supercomplexes" YML130C ERO1 None protein_folding* electron_carrier_activity endoplasmic_reticulum None None 13 13175 11484 YML130C S000004599 "ORF,_Verified" Thiol_oxidase_required_for_oxidative_protein_folding_in_the_endoplasmic_reticulum YML131W None None biological_process_unknown molecular_function_unknown cytoplasm None Up 13 10199 11296 YML131W S000004600 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function_with_similarity_to_medium_chain_dehydrogenase/reductases;_expression_induced_by_stresses_including_osmotic_shock,_DNA_damaging_agents,_and_other_chemicals;_GFP-fusion_protein_localizes_to_the_cytoplasm" YML132W COS3 None sodium_ion_homeostasis protein_binding vacuole_(sensu_Fungi)* None None 13 7244 8383 YML132W S000004601 "ORF,_Verified" "Protein_involved_in_salt_resistance;_interacts_with_sodium:hydrogen_antiporter_Nha1p;_member_of_the_DUP380_subfamily_of_conserved,_often_subtelomerically-encoded_proteins" YML133C None None biological_process_unknown helicase_activity mitochondrion G1 None 13 4684 461 YML133C S000004602 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function_with_similarity_to_helicases;_the_authentic,_non-tagged_protein_is_detected_in_highly_purified_mitochondria_in_high-throughput_studies;_YML133C_contains_an_intron" YMR001C CDC5 PKX2|MSD2 protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity nucleus* G2/M None 13 271136 269019 YMR001C S000004603 "ORF,_Verified" "Polo-like_kinase_with_similarity_to_Xenopus_Plx1_and_S._pombe_Plo1p;_found_at_bud_neck,_nucleus_and_SPBs;_has_multiple_functions_in_mitosis_and_cytokinesis_through_phosphorylation_of_substrates;_may_be_a_Cdc28p_substrate" YMR002W MIC17 None biological_process_unknown molecular_function_unknown cytoplasm* S/G2 None 13 272193 272663 YMR002W S000004604 "ORF,_Verified" Mitochondrial_intermembrane_space_cysteine_motif_protein;_MIC17_is_not_an_essential_gene YMR003W None None biological_process_unknown molecular_function_unknown mitochondrion S/G2 None 13 273118 273714 YMR003W S000004605 "ORF,_Uncharacterized" Protein_of_unknown_function;_GFP-fusion_protein_localizes_to_the_mitochondria;_null_mutant_is_viable_and_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation)_and_severe_growth_defect_in_minimal_glycerol_media YMR004W MVP1 None protein_targeting_to_vacuole molecular_function_unknown cytoplasm None Up 13 274017 275552 YMR004W S000004606 "ORF,_Verified" Protein_required_for_sorting_proteins_to_the_vacuole;_overproduction_of_Mvp1p_suppresses_several_dominant_VPS1_mutations;_Mvp1p_and_Vps1p_act_in_concert_to_promote_membrane_traffic_to_the_vacuole YMR005W TAF4 MPT1|TSG2|TAF48 transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_factor_activity transcription_factor_TFIID_complex None None 13 276045 277211 YMR005W S000004607 "ORF,_Verified" "TFIID_subunit_(48_kDa),_involved_in_RNA_polymerase_II_transcription_initiation;_potential_Cdc28p_substrate" YMR006C PLB2 None glycerophospholipid_metabolism lysophospholipase_activity cell_wall_(sensu_Fungi)* None None 13 279681 277561 YMR006C S000004608 "ORF,_Verified" Phospholipase_B_(lysophospholipase)_involved_in_phospholipid_metabolism;_displays_transacylase_activity_in_vitro;_overproduction_confers_resistance_to_lysophosphatidylcholine YMR008C PLB1 None glycerophospholipid_metabolism lysophospholipase_activity cell_wall_(sensu_Fungi) None None 13 282584 280590 YMR008C S000004610 "ORF,_Verified" "Phospholipase_B_(lysophospholipase)_involved_in_lipid_metabolism,_required_for_deacylation_of_phosphatidylcholine_and_phosphatidylethanolamine_but_not_phosphatidylinositol" YMR009W ADI1 None methionine_salvage "oxidoreductase_activity,_acting_on_single_donors_with_incorporation_of_molecular_oxygen,_incorporation_of_two_atoms_of_oxygen" cytoplasm* None None 13 284101 284640 YMR009W S000004611 "ORF,_Verified" Acireductone_dioxygenease_involved_in_the_methionine_salvage_pathway;_ortholog_of_human_MTCBP-1;_transcribed_with_YMR010W_and_regulated_post-transcriptionally_by_RNase_III_(Rnt1p)_cleavage;_ADI1_mRNA_is_induced_in_heat_shock_conditions YMR010W None None metabolism molecular_function_unknown cytoplasm None None 13 285099 286316 YMR010W S000004612 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YMR010W_is_not_an_essential_gene;_YMR010W_mRNA_is_transcribed_with_ADI1 YMR011W HXT2 None hexose_transport glucose_transporter_activity* plasma_membrane M/G1 None 13 288078 289703 YMR011W S000004613 "ORF,_Verified" "High-affinity_glucose_transporter_of_the_major_facilitator_superfamily,_expression_is_induced_by_low_levels_of_glucose_and_repressed_by_high_levels_of_glucose" YMR014W BUD22 None bud_site_selection molecular_function_unknown nucleus None None 13 298867 300426 YMR014W S000004616 "ORF,_Verified" Protein_involved_in_bud-site_selection;_diploid_mutants_display_a_random_budding_pattern_instead_of_the_wild-type_bipolar_pattern YMR015C ERG5 CYP61 ergosterol_biosynthesis C-22_sterol_desaturase_activity endoplasmic_reticulum G2/M None 13 302484 300868 YMR015C S000004617 "ORF,_Verified" "C-22_sterol_desaturase,_a_cytochrome_P450_enzyme_that_catalyzes_the_formation_of_the_C-22(23)_double_bond_in_the_sterol_side_chain_in_ergosterol_biosynthesis;_may_be_a_target_of_azole_antifungal_drugs" YMR016C SOK2 None pseudohyphal_growth transcription_factor_activity nucleus None None 13 305592 303235 YMR016C S000004618 "ORF,_Verified" Nuclear_protein_that_plays_a_regulatory_role_in_the_cyclic_AMP_(cAMP)-dependent_protein_kinase_(PKA)_signal_transduction_pathway;_negatively_regulates_pseudohyphal_differentiation;_homologous_to_several_transcription_factors YMR017W SPO20 DBI9 spore_wall_assembly_(sensu_Fungi)* t-SNARE_activity prospore_membrane None None 13 307488 308681 YMR017W S000004619 "ORF,_Verified" "Meiosis-specific_subunit_of_the_t-SNARE_complex,_required_for_prospore_membrane_formation_during_sporulation;_similar_to_but_not_functionally_redundant_with_Sec9p;_SNAP-25_homolog" YMR020W FMS1 None pantothenate_biosynthesis* amine_oxidase_activity cytoplasm None None 13 315376 316902 YMR020W S000004622 "ORF,_Verified" "Polyamine_oxidase,_converts_spermine_to_spermidine,_which_is_required_for_the_essential_hypusination_modification_of_translation_factor_eIF-5A;_also_involved_in_pantothenic_acid_biosynthesis" YMR021C MAC1 CUA1 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* specific_RNA_polymerase_II_transcription_factor_activity nucleus None None 13 318417 317164 YMR021C S000004623 "ORF,_Verified" Copper-sensing_transcription_factor_involved_in_regulation_of_genes_required_for_high_affinity_copper_transport YMR022W UBC7 QRI8 ER-associated_protein_catabolism* ubiquitin_conjugating_enzyme_activity endoplasmic_reticulum None None 13 318679 319176 YMR022W S000004624 "ORF,_Verified" "Ubiquitin_conjugating_enzyme,_involved_in_the_ER-associated_protein_degradation_pathway;_requires_Cue1p_for_recruitment_to_the_ER_membrane;_proposed_to_be_involved_in_chromatin_assembly" YMR023C MSS1 PET53 protein_biosynthesis* GTP_binding mitochondrial_inner_membrane None None 13 321016 319436 YMR023C S000004625 "ORF,_Verified" "Mitochondrial_protein,_forms_a_heterodimer_complex_with_Mto1p_that_performs_the_5-carboxymethylaminomethyl_modification_of_the_wobble_uridine_base_in_mitochondrial_tRNAs;_similar_to_human_GTPBP3" YMR024W MRPL3 None protein_biosynthesis structural_constituent_of_ribosome mitochondrial_large_ribosomal_subunit None None 13 321874 323046 YMR024W S000004626 "ORF,_Verified" Mitochondrial_ribosomal_protein_of_the_large_subunit YMR025W CSI1 None adaptation_to_pheromone_during_conjugation_with_cellular_fusion* molecular_function_unknown signalosome_complex None None 13 323299 324186 YMR025W S000004627 "ORF,_Verified" "Subunit_of_the_Cop9_signalosome,_which_is_required_for_deneddylation,_or_removal_of_the_ubiquitin-like_protein_Rub1p_from_Cdc53p_(cullin);_involved_in_adaptation_to_pheromone_signaling" YMR026C PEX12 PAS11 peroxisome_organization_and_biogenesis* protein_binding peroxisomal_membrane None None 13 325434 324235 YMR026C S000004628 "ORF,_Verified" C3HC4-type_RING-finger_peroxisomal_membrane_peroxin_required_for_peroxisome_biogenesis_and_peroxisomal_matrix_protein_import;_forms_translocation_subcomplex_with_Pex2p_and_Pex10p;_mutations_in_human_homolog_cause_peroxisomal_disorders YMR028W TAP42 None signal_transduction protein_binding cellular_component_unknown None Up 13 327481 328581 YMR028W S000004630 "ORF,_Verified" Essential_protein_involved_in_the_TOR_signaling_pathway;_physically_associates_with_the_protein_phosphatase_2A_and_the_SIT4_protein_phosphatase_catalytic_subunits YMR029C FAR8 None cell_cycle_arrest_in_response_to_pheromone molecular_function_unknown cellular_component_unknown None None 13 330230 328659 YMR029C S000004631 "ORF,_Verified" "Protein_involved_in_G1_cell_cycle_arrest_in_response_to_pheromone,_in_a_pathway_different_from_the_Far1p-dependent_pathway;_interacts_with_Far3p,_Far7p,_Far9p,_Far10p,_and_Far11p" YMR030W RSF1 None aerobic_respiration* molecular_function_unknown nucleus* None None 13 330792 331922 YMR030W S000004632 "ORF,_Verified" Protein_required_for_respiratory_growth;_localized_to_both_the_nucleus_and_mitochondrion;_mutant_displays_decreased_transcription_of_specific_nuclear_and_mitochondrial_genes_whose_products_are_involved_in_respiratory_growth YMR031C None None biological_process_unknown molecular_function_unknown cytoplasm* G2/M None 13 334742 332211 YMR031C S000004633 "ORF,_Uncharacterized" "Protein_of_unknown_function_with_similarity_to_Ykl050cp_and_Uso1p;_the_authentic,_non-tagged_protein_is_detected_in_a_phosphorylated_state_in_highly_purified_mitochondria_in_high-throughput_studies;_YMR031C_is_not_an_essential_gene" YMR032W HOF1 CYK2 cytokinesis cytoskeletal_protein_binding contractile_ring_(sensu_Saccharomyces) G2/M None 13 335297 337306 YMR032W S000004635 "ORF,_Verified" "Bud_neck-localized,_SH3_domain-containing_protein_required_for_cytokinesis;_regulates_actomyosin_ring_dynamics_and_septin_localization;_interacts_with_the_formins,_Bni1p_and_Bnr1p,_and_with_Cyk3p,_Vrp1p,_and_Bni5p" YMR033W ARP9 RSC12|SWP59 chromatin_remodeling general_RNA_polymerase_II_transcription_factor_activity nucleus* None None 13 337787 339276 YMR033W S000004636 "ORF,_Verified" Component_of_both_the_SWI/SNF_and_RSC_chromatin_remodeling_complexes;_actin-related_protein_involved_in_transcriptional_regulation YMR034C None None biological_process_unknown sterol_transporter_activity cellular_component_unknown None None 13 340721 339417 YMR034C S000004637 "ORF,_Uncharacterized" "Putative_transporter,_member_of_the_SLC10_carrier_family;_identified_in_a_transposon_mutagenesis_screen_as_a_gene_involved_in_azole_resistance;_YMR034C_is_not_an_essential_gene" YMR035W IMP2 None mitochondrial_protein_processing peptidase_activity* mitochondrial_inner_membrane_peptidase_complex None None 13 341141 341674 YMR035W S000004638 "ORF,_Verified" "Catalytic_subunit_of_the_mitochondrial_inner_membrane_peptidase_complex,_required_for_maturation_of_mitochondrial_proteins_of_the_intermembrane_space;_complex_contains_Imp1p_and_Imp2p_(both_catalytic_subunits),_and_Som1p" YMR036C MIH1 None G2/M_transition_of_mitotic_cell_cycle* protein_tyrosine_phosphatase_activity cytoplasm* None None 13 343519 341855 YMR036C S000004639 "ORF,_Verified" Protein_tyrosine_phosphatase_involved_in_cell_cycle_control;_regulates_the_phosphorylation_state_of_Cdc28p;_homolog_of_S._pombe_cdc25 YMR037C MSN2 None response_to_stress* DNA_binding* nucleus* None None 13 346516 344402 YMR037C S000004640 "ORF,_Verified" "Transcriptional_activator_related_to_Msn4p;_activated_in_stress_conditions,_which_results_in_translocation_from_the_cytoplasm_to_the_nucleus;_binds_DNA_at_stress_response_elements_of_responsive_genes,_inducing_gene_expression" YMR038C CCS1 LYS7|CCS intracellular_copper_ion_transport superoxide_dismutase_copper_chaperone_activity cytosol* None None 13 348259 347510 YMR038C S000004641 "ORF,_Verified" "Copper_chaperone_for_superoxide_dismutase_Sod1p,_involved_in_oxidative_stress_protection;_Met-X-Cys-X2-Cys_motif_within_the_N-terminal_portion_is_involved_in_insertion_of_copper_into_Sod1p_under_conditions_of_copper_deprivation" YMR039C SUB1 TSP1 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* transcription_coactivator_activity nucleus None None 13 349521 348643 YMR039C S000004642 "ORF,_Verified" "Transcriptional_coactivator,_facilitates_elongation_by_influencing_enzymes_that_modify_RNAP_II,_acts_in_a_peroxide_resistance_pathway_involving_Rad2p;_suppressor_of_TFIIB_mutations" YMR040W YET2 None biological_process_unknown molecular_function_unknown integral_to_membrane None None 13 350380 350862 YMR040W S000004643 "ORF,_Verified" "Protein_of_unknown_function_that_may_interact_with_ribosomes,_based_on_co-purification_experiments;_homolog_of_human_BAP31_protein" YMR041C ARA2 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 351972 350965 YMR041C S000004644 "ORF,_Verified" "NAD-dependent_arabinose_dehydrogenase,_involved_in_biosynthesis_of_erythroascorbic_acid;_similar_to_plant_L-galactose_dehydrogenase" YMR042W ARG80 ARGRI|ARGR1 positive_regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus None None 13 352602 353135 YMR042W S000004645 "ORF,_Verified" Transcription_factor_involved_in_regulation_of_arginine-responsive_genes;_acts_with_Arg81p_and_Arg82p YMR043W MCM1 FUN80 regulation_of_transcription_from_RNA_polymerase_II_promoter* DNA_binding* nucleus* None None 13 353870 354730 YMR043W S000004646 "ORF,_Verified" Transcription_factor_involved_in_cell-type-specific_transcription_and_pheromone_response;_plays_a_central_role_in_the_formation_of_both_repressor_and_activator_complexes YMR044W IOC4 None chromatin_remodeling protein_binding ISW1_complex None None 13 355383 356810 YMR044W S000004647 "ORF,_Verified" "Member_of_a_complex_(Isw1b)_with_Isw1p_and_Ioc2p_that_exhibits_nucleosome-stimulated_ATPase_activity_and_acts_within_coding_regions_to_coordinate_transcription_elongation_with_termination_and_processing,_contains_a_PWWP_motif" YMR045C None None None None None None None 13 362626 357358 YMR045C S000004648 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YMR046C None None None None None None None 13 362626 361304 YMR046C S000004649 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YMR047C NUP116 NSP116 mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 13 366704 363363 YMR047C S000004650 "ORF,_Verified" Subunit_of_the_nuclear_pore_complex_(NPC)_that_is_localized_to_both_sides_of_the_pore;_contains_a_repetitive_GLFG_motif_that_interacts_with_mRNA_export_factor_Mex67p_and_with_karyopherin_Kap95p;_homologous_to_Nup100p YMR049C ERB1 None rRNA_processing molecular_function_unknown nucleus* None None 13 370516 368093 YMR049C S000004652 "ORF,_Verified" Protein_required_for_maturation_of_the_25S_and_5.8S_ribosomal_RNAs;_constituent_of_66S_pre-ribosomal_particles;_homologous_to_mammalian_Bop1 YMR050C None None None None None None None 13 378324 373056 YMR050C S000004653 "transposable_element_gene,_None" "Retrotransposon_TYA_Gag_and_TYB_Pol_genes;_transcribed/translated_as_one_unit;_polyprotein_is_processed_to_make_a_nucleocapsid-like_protein_(Gag),_reverse_transcriptase_(RT),_protease_(PR),_and_integrase_(IN);_similar_to_retroviral_genes" YMR051C None None None None None None None 13 378324 377002 YMR051C S000004654 "transposable_element_gene,_None" Retrotransposon_TYA_Gag_gene_co-transcribed_with_TYB_Pol;_translated_as_TYA_or_TYA-TYB_polyprotein;_Gag_is_a_nucleocapsid_protein_that_is_the_structural_constituent_of_virus-like_particles_(VLPs);_similar_to_retroviral_Gag YMR052W FAR3 None cell_cycle_arrest_in_response_to_pheromone molecular_function_unknown endoplasmic_reticulum None None 13 379585 380199 YMR052W S000004656 "ORF,_Verified" "Protein_involved_in_G1_cell_cycle_arrest_in_response_to_pheromone,_in_a_pathway_different_from_the_Far1p-dependent_pathway;_interacts_with_Far7p,_Far8p,_Far9p,_Far10p,_and_Far11p" YMR054W STV1 None vacuolar_acidification "hydrogen-transporting_ATPase_activity,_rotational_mechanism" Golgi_apparatus* None None 13 383302 385974 YMR054W S000004658 "ORF,_Verified" "Subunit_a_of_the_vacuolar-ATPase_V0_domain,_one_of_two_isoforms_(Stv1p_and_Vph1p);_Stv1p_is_located_in_V-ATPase_complexes_of_the_Golgi_and_endosomes_while_Vph1p_is_located_in_V-ATPase_complexes_of_the_vacuole" YMR056C AAC1 None aerobic_respiration* ATP:ADP_antiporter_activity mitochondrial_inner_membrane None None 13 388243 387314 YMR056C S000004660 "ORF,_Verified" "Mitochondrial_inner_membrane_ADP/ATP_translocator,_exchanges_cytosolic_ADP_for_mitochondrially_synthesized_ATP;_phosphorylated;_Aac1p_is_a_minor_isoform_while_Pet9p_is_the_major_ADP/ATP_translocator" YMR058W FET3 None high_affinity_iron_ion_transport* ferroxidase_activity plasma_membrane G2/M None 13 388821 390731 YMR058W S000004662 "ORF,_Verified" "Ferro-O2-oxidoreductase_required_for_high-affinity_iron_uptake_and_involved_in_mediating_resistance_to_copper_ion_toxicity,_belongs_to_class_of_integral_membrane_multicopper_oxidases" YMR061W RNA14 None mRNA_polyadenylylation* RNA_binding* nucleus* None Up 13 392754 394787 YMR061W S000004665 "ORF,_Verified" Cleavage_and_polyadenylation_factor_I_(CF_I)_component_involved_in_cleavage_and_polyadenylation_of_mRNA_3'_ends;_bridges_interaction_between_Rna15p_and_Hrp1p_in_the_CF_I_complex YMR062C ECM40 ARG7 cell_wall_organization_and_biogenesis* amino-acid_N-acetyltransferase_activity* mitochondrial_matrix None Up 13 396378 395053 YMR062C S000004666 "ORF,_Verified" "Mitochondrial_ornithine_acetyltransferase,_catalyzes_the_fifth_step_in_arginine_biosynthesis;_also_possesses_acetylglutamate_synthase_activity,_regenerates_acetylglutamate_while_forming_ornithine" YMR064W AEP1 NCA1 protein_biosynthesis molecular_function_unknown mitochondrion None None 13 397902 399458 YMR064W S000004668 "ORF,_Verified" Protein_required_for_expression_of_the_mitochondrial_OLI1_gene_encoding_subunit_9_of_F1-F0_ATP_synthase YMR067C UBX4 CUI1 ubiquitin-dependent_protein_catabolism* molecular_function_unknown cytoplasm* None None 13 405572 404322 YMR067C S000004671 "ORF,_Verified" UBX_(ubiquitin_regulatory_X)_domain-containing_protein_that_interacts_with_Cdc48p YMR068W AVO2 None regulation_of_cell_growth* molecular_function_unknown cytoplasm* None None 13 406303 407583 YMR068W S000004672 "ORF,_Verified" "Component_of_a_complex_containing_the_Tor2p_kinase_and_other_proteins,_which_may_have_a_role_in_regulation_of_cell_growth" YMR070W MOT3 ROX7 transcription DNA_binding* nucleus None None 13 409153 410625 YMR070W S000004674 "ORF,_Verified" "Nuclear_transcription_factor_with_two_Cys2-His2_zinc_fingers;_involved_in_repression_of_a_subset_of_hypoxic_genes_by_Rox1p,_repression_of_several_DAN/TIR_genes_during_aerobic_growth,_and_repression_of_ergosterol_biosynthetic_genes" YMR071C TVP18 None biological_process_unknown molecular_function_unknown clathrin-coated_vesicle* None None 13 411264 410761 YMR071C S000004675 "ORF,_Verified" "Integral_membrane_protein_localized_to_late_Golgi_vesicles_along_with_the_v-SNARE_Tlg2p;_may_interact_with_ribosomes,_based_on_co-purification_experiments" YMR072W ABF2 None mitochondrial_genome_maintenance* DNA_binding* mitochondrial_nucleoid* None None 13 411568 412119 YMR072W S000004676 "ORF,_Verified" "Mitochondrial_DNA-binding_protein_involved_in_mitochondrial_DNA_replication_and_recombination,_member_of_HMG1_DNA-binding_protein_family;_activity_may_be_regulated_by_protein_kinase_A_phosphorylation" YMR073C IRC21 None biological_process_unknown molecular_function_unknown cytoplasm None None 13 412872 412267 YMR073C S000004677 "ORF,_Verified" Putative_protein_of_unknown_function;_proposed_to_be_involved_in_resistance_to_carboplatin_and_cisplatin;_shares_similarity_to_a_human_cytochrome_oxidoreductase;_null_mutant_displays_increased_levels_of_spontaneous_Rad52p_foci YMR075W RCO1 None biological_process_unknown molecular_function_unknown nucleus None None 13 413981 416035 YMR075W S000004680 "ORF,_Verified" Essential_subunit_of_the_histone_deacetylase_Rpd3S_complex;_interacts_with_Eaf3p YMR077C VPS20 VPL10|VPT20|CHM6 late_endosome_to_vacuole_transport* molecular_function_unknown cytoplasm* None None 13 422148 421483 YMR077C S000004682 "ORF,_Verified" "Myristoylated_subunit_of_ESCRTIII,_the_endosomal_sorting_complex_required_for_transport_of_transmembrane_proteins_into_the_multivesicular_body_pathway_to_the_lysosomal/vacuolar_lumen;_cytoplasmic_protein_recruited_to_endosomal_membranes" YMR078C CTF18 CHL12 mitotic_sister_chromatid_cohesion molecular_function_unknown mitochondrion* G1 None 13 424727 422502 YMR078C S000004683 "ORF,_Verified" Subunit_of_a_complex_with_Ctf8p_that_shares_some_subunits_with_Replication_Factor_C_and_is_required_for_sister_chromatid_cohesion;_may_have_overlapping_functions_with_Rad24p_in_the_DNA_damage_replication_checkpoint YMR080C NAM7 UPF1|MOF4|IFS2 mRNA_catabolism* ATP-dependent_RNA_helicase_activity* cytoplasm* None None 13 429626 426711 YMR080C S000004685 "ORF,_Verified" "ATP-dependent_RNA_helicase_of_the_SFI_superfamily,_required_for_nonsense_mediated_mRNA_decay_and_for_efficient_translation_termination_at_nonsense_codons;_involved_in_telomere_maintenance;_potentially_has_E3_ubiquitin_ligase_activity" YMR081C ISF1 MBR3 aerobic_respiration molecular_function_unknown cellular_component_unknown None None 13 431094 430078 YMR081C S000004686 "ORF,_Verified" "Serine-rich,_hydrophilic_protein_with_similarity_to_Mbr1p;_overexpression_suppresses_growth_defects_of_hap2,_hap3,_and_hap4_mutants;_expression_is_under_glucose_control;_cotranscribed_with_NAM7_in_a_cyp1_mutant" YMR083W ADH3 None fermentation alcohol_dehydrogenase_activity mitochondrial_matrix* None None 13 434787 435914 YMR083W S000004688 "ORF,_Verified" Mitochondrial_alcohol_dehydrogenase_isozyme_III;_involved_in_the_shuttling_of_mitochondrial_NADH_to_the_cytosol_under_anaerobic_conditions_and_ethanol_production YMR085W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 437490 438788 YMR085W S000004690 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YMR085W_and_adjacent_ORF_YMR084W_are_merged_in_related_strains YMR086W None None biological_process_unknown molecular_function_unknown cytoplasm None None 13 439207 442089 YMR086W S000004692 "ORF,_Verified" "Protein_of_unknown_function_that_may_interact_with_ribosomes,_based_on_co-purification_experiments;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cell_periphery;_cAMP_represses_YMR086W_expression" YMR087W None None tRNA_splicing phosphoric_monoester_hydrolase_activity cellular_component_unknown None Up 13 442526 443380 YMR087W S000004693 "ORF,_Verified" Putative_ADP-ribose-1''-monophosphatase_that_converts_ADP-ribose-1''-monophosphate_to_ADP-ribose;_may_have_a_role_in_tRNA_splicing;_contains_an_A1pp_domain YMR088C VBA1 None basic_amino_acid_transport basic_amino_acid_permease_activity vacuolar_membrane_(sensu_Fungi) None None 13 445101 443413 YMR088C S000004694 "ORF,_Verified" Permease_of_basic_amino_acids_in_the_vacuolar_membrane YMR089C YTA12 RCA1 protein_complex_assembly* ATPase_activity* cytoplasm* None Up 13 448085 445608 YMR089C S000004695 "ORF,_Verified" "Component,_with_Afg3p,_of_the_mitochondrial_inner_membrane_m-AAA_protease_that_mediates_degradation_of_misfolded_or_unassembled_proteins_and_is_also_required_for_correct_assembly_of_mitochondrial_enzyme_complexes" YMR090W None None biological_process_unknown molecular_function_unknown cytoplasm None Up 13 449244 449927 YMR090W S000004696 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function_with_similarity_to_DTDP-glucose_4,6-dehydratases;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cytoplasm;_YMR090W_is_not_an_essential_gene" YMR091C NPL6 RSC7 protein_import_into_nucleus molecular_function_unknown nucleus* None None 13 451364 450057 YMR091C S000004697 "ORF,_Verified" "Component_of_the_RSC_chromatin_remodeling_complex;_interacts_with_Rsc3p,_Rsc30p,_Ldb7p,_and_Htl1p_to_form_a_module_important_for_a_broad_range_of_RSC_functions;_involved_in_nuclear_protein_import_and_maintenance_of_proper_telomere_length" YMR092C AIP1 None response_to_osmotic_stress* protein_binding cytoplasm* None Up 13 453478 451631 YMR092C S000004698 "ORF,_Verified" "Actin_cortical_patch_component,_interacts_with_the_actin_depolymerizing_factor_cofilin;_required_to_restrict_cofilin_localization_to_cortical_patches;_contains_WD_repeats" YMR093W UTP15 None processing_of_20S_pre-rRNA snoRNA_binding small_nucleolar_ribonucleoprotein_complex None None 13 454014 455555 YMR093W S000004699 "ORF,_Verified" "Nucleolar_protein,_component_of_the_small_subunit_(SSU)_processome_containing_the_U3_snoRNA_that_is_involved_in_processing_of_pre-18S_rRNA" YMR094W CTF13 CBF3C kinetochore_assembly DNA_bending_activity* condensed_nuclear_chromosome_kinetochore* None None 13 455824 457260 YMR094W S000004700 "ORF,_Verified" "Subunit_of_the_CBF3_complex,_which_binds_to_the_CDE_III_element_of_centromeres,_bending_the_DNA_upon_binding,_and_may_be_involved_in_sister_chromatid_cohesion_during_mitosis" YMR095C SNO1 None pyridoxine_metabolism* molecular_function_unknown cytoplasm None Up 13 457958 457284 YMR095C S000004701 "ORF,_Verified" "Protein_of_unconfirmed_function,_involved_in_pyridoxine_metabolism;_expression_is_induced_during_stationary_phase;_forms_a_putative_glutamine_amidotransferase_complex_with_Snz1p,_with_Sno1p_serving_as_the_glutaminase" YMR096W SNZ1 None pyridoxine_metabolism* protein_binding cellular_component_unknown None Up 13 458407 459300 YMR096W S000004702 "ORF,_Verified" "Protein_involved_in_vitamin_B6_biosynthesis;_member_of_a_stationary_phase-induced_gene_family;_coregulated_with_SNO1;_interacts_with_Sno1p_and_with_Yhr198p,_perhaps_as_a_multiprotein_complex_containing_other_Snz_and_Sno_proteins" YMR097C MTG1 None protein_biosynthesis* GTPase_activity mitochondrial_inner_membrane None None 13 460526 459423 YMR097C S000004703 "ORF,_Verified" "Peripheral_GTPase_of_the_mitochondrial_inner_membrane,_essential_for_respiratory_competence,_likely_functions_in_assembly_of_the_large_ribosomal_subunit,_has_homologs_in_plants_and_animals" YMR098C ATP25 LRC4 biological_process_unknown molecular_function_unknown mitochondrion None None 13 462608 460770 YMR098C S000004704 "ORF,_Verified" Mitochondrial_protein_required_for_the_stability_of_Oli1p_(Atp9p)_mRNA_and_for_the_Oli1p_ring_formation;_null_mutant_displays_decreased_frequency_of_mitochondrial_genome_loss_(petite_formation) YMR099C None None biological_process_unknown molecular_function_unknown cytoplasm* None None 13 464826 463933 YMR099C S000004705 "ORF,_Verified" "Glucose-6-phosphate_1-epimerase_(hexose-6-phosphate_mutarotase),_likely_involved_in_carbohydrate_metabolism;_GFP-fusion_protein_localizes_to_both_the_nucleus_and_cytoplasm_and_is_induced_in_response_to_the_DNA-damaging_agent_MMS" YMR100W MUB1 None regulation_of_cell_budding molecular_function_unknown cellular_component_unknown None None 13 466299 468161 YMR100W S000004706 "ORF,_Verified" Protein_that_interacts_with_E2_and_E3_enzymes_Ubr2p_and_Rad6p_and_is_required_for_ubiquitylation_and_degradation_of_Rpn4p;_contains_a_MYND_domain_(residues_512_to_555);_has_a_short_half-life;_has_similarity_to_Aspergillus_nidulans_samB_gene YMR102C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 472351 469847 YMR102C S000004708 "ORF,_Uncharacterized" Protein_of_unknown_function;_transcription_is_activated_by_paralogous_transcription_factors_Yrm1p_and_Yrr1p_along_with_genes_involved_in_multidrug_resistance;_mutant_shows_increased_resistance_to_azoles;_YMR102C_is_not_an_essential_gene YMR104C YPK2 YKR2 protein_amino_acid_phosphorylation protein_kinase_activity cytoplasm* None None 13 475452 473419 YMR104C S000004710 "ORF,_Verified" Protein_kinase_with_similarityto_serine/threonine_protein_kinase_Ypk1p;_functionally_redundant_with_YPK1_at_the_genetic_level;_participates_in_a_signaling_pathway_required_for_optimal_cell_wall_integrity;_homolog_of_mammalian_kinase_SGK YMR106C YKU80 HDF2 double-strand_break_repair_via_nonhomologous_end-joining* RNA_binding* nuclear_chromatin* None None 13 480189 478300 YMR106C S000004712 "ORF,_Verified" "Subunit_of_the_telomeric_Ku_complex_(Yku70p-Yku80p),_involved_in_telomere_length_maintenance,_structure_and_telomere_position_effect;_relocates_to_sites_of_double-strand_cleavage_to_promote_nonhomologous_end_joining_during_DSB_repair" YMR108W ILV2 THI1|SMR1 branched_chain_family_amino_acid_biosynthesis acetolactate_synthase_activity* mitochondrion* None None 13 484083 486146 YMR108W S000004714 "ORF,_Verified" "Acetolactate_synthase,_catalyses_the_first_common_step_in_isoleucine_and_valine_biosynthesis_and_is_the_target_of_several_classes_of_inhibitors,_localizes_to_the_mitochondria;_expression_of_the_gene_is_under_general_amino_acid_control" YMR109W MYO5 None cell_wall_organization_and_biogenesis* microfilament_motor_activity actin_cortical_patch None None 13 486586 490245 YMR109W S000004715 "ORF,_Verified" "One_of_two_type_I_myosins;_contains_proline-rich_tail_homology_2_(TH2)_and_SH3_domains;_MYO5_deletion_has_little_effect_on_growth,_but_myo3_myo5_double_deletion_causes_severe_defects_in_growth_and_actin_cytoskeleton_organization" YMR110C HFD1 None biological_process_unknown molecular_function_unknown mitochondrion* None None 13 491991 490393 YMR110C S000004716 "ORF,_Verified" "Putative_fatty_aldehyde_dehydrogenase,_located_in_the_mitochondrial_outer_membrane_and_also_in_lipid_particles;_has_similarity_to_human_fatty_aldehyde_dehydrogenase_(FALDH)_which_is_implicated_in_Sjogren-Larsson_syndrome" YMR111C None None biological_process_unknown molecular_function_unknown nucleus None Up 13 493791 492403 YMR111C S000004717 "ORF,_Uncharacterized" Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus;_YMR111C_is_not_an_essential_gene YMR112C MED11 None transcription_from_RNA_polymerase_II_promoter RNA_polymerase_II_transcription_mediator_activity mediator_complex None None 13 494494 494099 YMR112C S000004718 "ORF,_Verified" Subunit_of_the_RNA_polymerase_II_mediator_complex;_associates_with_core_polymerase_subunits_to_form_the_RNA_polymerase_II_holoenzyme;_essential_protein YMR113W FOL3 None folic_acid_and_derivative_biosynthesis dihydrofolate_synthase_activity cytoplasm None None 13 494998 496281 YMR113W S000004719 "ORF,_Verified" "Dihydrofolate_synthetase,_involved_in_folic_acid_biosynthesis;_catalyzes_the_conversion_of_dihydropteroate_to_dihydrofolate_in_folate_coenzyme_biosynthesis" YMR114C None None biological_process_unknown molecular_function_unknown cytoplasm* None Up 13 497448 496342 YMR114C S000004720 "ORF,_Verified" "Protein_of_unknown_function;_may_interact_with_ribosomes,_based_on_co-purification_experiments;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_nucleus_and_cytoplasm;_YMR114C_is_not_an_essential_gene" YMR115W None FMP24 biological_process_unknown molecular_function_unknown mitochondrion None Up 13 497703 499208 YMR115W S000004721 "ORF,_Uncharacterized" Putative_protein_involved_in_mitochondrial_protein_degradation;_required_for_viability_of_cells_lacking_a_mitochondrial_genome;_detected_in_highly_purified_mitochondria_in_high-throughput_studies YMR116C ASC1 CPC2 negative_regulation_of_translation molecular_function_unknown cytoplasm* None None 13 500687 499455 YMR116C S000004722 "ORF,_Verified" G-protein_beta_subunit_and_guanine_nucleotide_dissociation_inhibitor_for_Gpa2p;_ortholog_of_RACK1_that_inhibits_translation;_core_component_of_the_small_(40S)_ribosomal_subunit;_represses_Gcn4p_in_the_absence_of_amino_acid_starvation YMR117C SPC24 None chromosome_segregation* structural_constituent_of_cytoskeleton condensed_nuclear_chromosome_kinetochore* None None 13 501890 501249 YMR117C S000004723 "ORF,_Verified" "Component_of_the_evolutionarily_conserved_kinetochore-associated_Ndc80_complex_(Ndc80p-Nuf2p-Spc24p-Spc25p);_involved_in_chromosome_segregation,_spindle_checkpoint_activity_and_kinetochore_clustering" YMR118C None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 502733 502143 YMR118C S000004724 "ORF,_Uncharacterized" Protein_of_unknown_function_with_similarity_to_succinate_dehydrogenase_cytochrome_b_subunit;_YMR118C_is_not_an_essential_gene YMR119W ASI1 None ubiquitin-dependent_protein_catabolism ubiquitin-protein_ligase_activity endoplasmic_reticulum_membrane None None 13 505332 507206 YMR119W S000004725 "ORF,_Verified" Putative_integral_membrane_E3_ubiquitin_ligase;_acts_with_Asi2p_and_Asi3p_to_ensure_the_fidelity_of_SPS-sensor_signalling_by_maintaining_the_dormant_repressed_state_of_gene_expression_in_the_absence_of_inducing_signals YMR120C ADE17 None de_novo'_IMP_biosynthesis* IMP_cyclohydrolase_activity* cytosol None None 13 509279 507501 YMR120C S000004727 "ORF,_Verified" "Enzyme_of_'de_novo'_purine_biosynthesis_containing_both_5-aminoimidazole-4-carboxamide_ribonucleotide_transformylase_and_inosine_monophosphate_cyclohydrolase_activities,_isozyme_of_Ade16p;_ade16_ade17_mutants_require_adenine_and_histidine" YMR121C RPL15B None protein_biosynthesis structural_constituent_of_ribosome* cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 13 510347 509733 YMR121C S000004728 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl15Ap_and_has_similarity_to_rat_L15_ribosomal_protein;_binds_to_5.8_S_rRNA" YMR123W PKR1 None biological_process_unknown molecular_function_unknown endoplasmic_reticulum None None 13 513592 513960 YMR123W S000004730 "ORF,_Verified" "V-ATPase_assembly_factor,_functions_with_other_V-ATPase_assembly_factors_in_the_ER_to_efficiently_assemble_the_V-ATPase_membrane_sector_(V0);_overproduction_confers_resistance_to_Pichia_farinosa_killer_toxin" YMR124W None None biological_process_unknown molecular_function_unknown cytoplasm None None 13 514455 517286 YMR124W S000004731 "ORF,_Uncharacterized" "Protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_cell_periphery,_cytoplasm,_bud,_and_bud_neck;_interacts_with_Crm1p_in_two-hybrid_assay;_YMR124W_is_not_an_essential_gene" YMR125W STO1 SUT1|CBP80|GCR3|CBC1 "nuclear_mRNA_splicing,_via_spliceosome*" mRNA_binding commitment_complex* None None 13 517538 520445 YMR125W S000004732 "ORF,_Verified" "Large_subunit_of_the_nuclear_mRNA_cap-binding_protein_complex,_interacts_with_Npl3p_to_carry_nuclear_poly(A)+_mRNA_to_cytoplasm;_also_involved_in_nuclear_mRNA_degradation_and_telomere_maintenance;_orthologous_to_mammalian_CBP80" YMR126C DLT1 None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 521788 520760 YMR126C S000004733 "ORF,_Uncharacterized" "Protein_of_unknown_function,_mutant_sensitive_to_6-azauracil_(6AU)_and_mycophenolic_acid_(MPA)" YMR127C SAS2 None chromatin_silencing_at_telomere acetyltransferase_activity* nuclear_chromatin* None None 13 523344 522328 YMR127C S000004734 "ORF,_Verified" "Histone_acetyltransferase_(HAT)_catalytic_subunit_of_the_SAS_complex_(Sas2p-Sas4p-Sas5p),_which_acetylates_free_histones_and_nucleosomes_and_regulates_transcriptional_silencing;_member_of_the_MYSTacetyltransferase_family" YMR128W ECM16 DHR1 processing_of_20S_pre-rRNA* RNA_helicase_activity mitochondrion* None None 13 523695 527498 YMR128W S000004735 "ORF,_Verified" "Essential_DEAH-box_ATP-dependent_RNA_helicase_specific_to_the_U3_snoRNP,_predominantly_nucleolar_in_distribution,_required_for_18S_rRNA_synthesis" YMR129W POM152 None mRNA_export_from_nucleus* structural_molecule_activity mitochondrion* None None 13 527803 531816 YMR129W S000004736 "ORF,_Verified" Nuclear_pore_membrane_glycoprotein;_may_be_involved_in_duplication_of_nuclear_pores_and_nuclear_pore_complexes_during_S-phase; YMR130W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 532118 533026 YMR130W S000004737 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_YMR130W_is_not_an_essential_gene YMR131C RRB1 None ribosome_biogenesis molecular_function_unknown nucleolus None None 13 534697 533162 YMR131C S000004738 "ORF,_Verified" Essential_nuclear_protein_involved_in_early_steps_of_ribosome_biogenesis;_physically_interacts_with_the_ribosomal_protein_Rpl3p YMR132C JLP2 None biological_process_unknown molecular_function_unknown cytoplasm None None 13 535569 534943 YMR132C S000004739 "ORF,_Uncharacterized" "Protein_of_unknown_function,_contains_sequence_that_closely_resembles_a_J_domain_(typified_by_the_E._coli_DnaJ_protein)" YMR134W None None mitochondrion_organization_and_biogenesis* molecular_function_unknown cytoplasm* None None 13 537837 538550 YMR134W S000004741 "ORF,_Uncharacterized" Protein_that_binds_to_and_regulates_Erg25p;_localized_to_the_ER;_null_mutant_is_viable_in_a_respiratory_defective_background;_synthetic_lethal_with_mmt1_and_mmt2_mutations;_highly_conserved_in_ascomycetes YMR135C GID8 DCR1 negative_regulation_of_gluconeogenesis* molecular_function_unknown cytoplasm* None Up 13 540055 538688 YMR135C S000004742 "ORF,_Verified" "Protein_of_unknown_function,_involved_in_proteasome-dependent_catabolite_inactivation_of_fructose-1,6-bisphosphatase;_contains_LisH_and_CTLH_domains,_like_Vid30p;_dosage-dependent_regulator_of_START" YMR136W GAT2 None transcription transcription_factor_activity nucleus None None 13 541198 542880 YMR136W S000004744 "ORF,_Verified" Protein_containing_GATA_family_zinc_finger_motifs;_similar_to_Gln3p_and_Dal80p;_expression_repressed_by_leucine YMR138W CIN4 UGX1|GTP1 microtubule-based_process GTP_binding cytoplasm None None 13 545154 545729 YMR138W S000004746 "ORF,_Verified" "GTP-binding_protein_involved_in_beta-tubulin_(Tub2p)_folding;_isolated_as_mutant_with_increased_chromosome_loss_and_sensitivity_to_benomyl;_regulated_by_the_GTPase-activating_protein,_Cin2p,_the_human_retinitis_pigmentosa_2_(RP2)_homolog" YMR139W RIM11 MDS1|GSK3 protein_amino_acid_phosphorylation* protein_serine/threonine_kinase_activity* cytoplasm None None 13 546124 547236 YMR139W S000004747 "ORF,_Verified" Protein_kinase_required_for_signal_transduction_during_entry_into_meiosis;_promotes_the_formation_of_the_Ime1p-Ume6p_complex_by_phosphorylating_Ime1p_and_Ume6p;_shares_similarity_with_mammalian_glycogen_synthase_kinase_3-beta YMR140W SIP5 None cellular_response_to_glucose_starvation molecular_function_unknown cytoplasm None None 13 547713 549182 YMR140W S000004748 "ORF,_Verified" Protein_of_unknown_function;_interacts_with_both_the_Reg1p/Glc7p_phosphatase_and_the_Snf1p_kinase YMR142C RPL13B None protein_biosynthesis structural_constituent_of_ribosome cytosolic_large_ribosomal_subunit_(sensu_Eukaryota) None None 13 551206 550205 YMR142C S000004750 "ORF,_Verified" "Protein_component_of_the_large_(60S)_ribosomal_subunit,_nearly_identical_to_Rpl13Ap;_not_essential_for_viability;_has_similarity_to_rat_L13_ribosomal_protein" YMR143W RPS16A None protein_biosynthesis structural_constituent_of_ribosome cytosolic_small_ribosomal_subunit_(sensu_Eukaryota) None None 13 551927 552902 YMR143W S000004751 "ORF,_Verified" Protein_component_of_the_small_(40S)_ribosomal_subunit;_identical_to_Rps16Bp_and_has_similarity_to_E._coli_S9_and_rat_S16_ribosomal_proteins YMR144W None None biological_process_unknown molecular_function_unknown nucleus S None 13 553361 554389 YMR144W S000004752 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_localized_to_the_nucleus;_YMR144W_is_not_an_essential_gene YMR145C NDE1 NDH1 ethanol_fermentation* NADH_dehydrogenase_activity mitochondrion G2/M None 13 556474 554792 YMR145C S000004753 "ORF,_Verified" "Mitochondrial_external_NADH_dehydrogenase,_a_type_II_NAD(P)H:quinone_oxidoreductase_that_catalyzes_the_oxidation_of_cytosolic_NADH;_Nde1p_and_Nde2p_provide_cytosolic_NADH_to_the_mitochondrial_respiratory_chain" YMR146C TIF34 None translational_initiation translation_initiation_factor_activity eukaryotic_translation_initiation_factor_3_complex None None 13 558523 557480 YMR146C S000004754 "ORF,_Verified" "Subunit_of_the_core_complex_of_translation_initiation_factor_3(eIF3),_which_is_essential_for_translation" YMR147W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 559198 559869 YMR147W S000004755 "ORF,_Uncharacterized" Putative_protein_of_unknown_function YMR148W None None biological_process_unknown molecular_function_unknown integral_to_membrane None None 13 560365 560811 YMR148W S000004756 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_predicted_to_contain_a_transmembrane_domain;_YMR148W_is_not_an_essential_gene YMR149W SWP1 None protein_amino_acid_N-linked_glycosylation dolichyl-diphosphooligosaccharide-protein_glycotransferase_activity oligosaccharyl_transferase_complex None None 13 560995 561855 YMR149W S000004757 "ORF,_Verified" "Delta_subunit_of_the_oligosaccharyl_transferase_glycoprotein_complex,_which_is_required_for_N-linked_glycosylation_of_proteins_in_the_endoplasmic_reticulum" YMR150C IMP1 PET-TS2858 mitochondrial_protein_processing peptidase_activity* mitochondrial_inner_membrane_peptidase_complex None None 13 562527 561955 YMR150C S000004758 "ORF,_Verified" "Catalytic_subunit_of_the_mitochondrial_inner_membrane_peptidase_complex,_required_for_maturation_of_mitochondrial_proteins_of_the_intermembrane_space;_complex_contains_Imp1p_and_Imp2p_(both_catalytic_subunits),_and_Som1p" YMR153W NUP53 None mRNA_export_from_nucleus* structural_molecule_activity nuclear_pore None None 13 564434 565861 YMR153W S000004762 "ORF,_Verified" "Subunit_of_the_nuclear_pore_complex_(NPC),_interacts_with_karyopherin_Kap121p_or_with_Nup170p_via_overlapping_regions_of_Nup53p,_involved_in_activation_of_the_spindle_checkpoint_mediated_by_the_Mad1p-Mad2p_complex" YMR154C RIM13 CPL1 protein_processing cysteine-type_endopeptidase_activity cellular_component_unknown None None 13 568181 565998 YMR154C S000004763 "ORF,_Verified" Calpain-like_cysteine_protease_involved_in_proteolytic_activation_of_Rim101p_in_response_to_alkaline_pH;_has_similarity_to_A._nidulans_palB YMR155W None None biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 568550 570193 YMR155W S000004764 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_identified_as_interacting_with_Hsp82p_in_a_high-throughput_two-hybrid_screen YMR156C TPP1 None DNA_repair polynucleotide_3'-phosphatase_activity cellular_component_unknown None None 13 571015 570299 YMR156C S000004765 "ORF,_Verified" "DNA_3'-phosphatase_that_functions_in_repair_of_endogenous_damage_of_double-stranded_DNA,_activity_is_specific_for_removal_of_3'_phosphates_at_strand_breaks;_has_similarity_to_the_l-2-haloacid_dehalogenase_superfamily" YMR157C None FMP39 biological_process_unknown molecular_function_unknown mitochondrion None None 13 572043 571276 YMR157C S000004766 "ORF,_Uncharacterized" Protein_of_unknown_function;_non-tagged_protein_is_detected_in_purified_mitochondria_in_high-throughput_studies;_null_mutant_displays_increased_frequency_of_mitochondrial_genome_loss_and_reduced_growth_rate_in_minimal_glycerol_media YMR158C-A None YMR158C-B biological_process_unknown molecular_function_unknown cellular_component_unknown None None 13 573330 573193 YMR158C-B S000007249 "ORF,_Uncharacterized" "Putative_protein_of_unknown_function,_may_contain_a_lipid_attachment_site;_YMR158C-A_is_not_an_essential_gene" YMR159C ATG16 APG15|APG16|CVT11|SAP18 autophagy molecular_function_unknown membrane_fraction None None 13 574927 574475 YMR159C S000004769 "ORF,_Verified" "Conserved_protein_that_interacts_with_Atg12p-Atg5p_conjugates_to_form_Atg12p-Atg5p-Atg16p_multimers,_which_localize_to_the_pre-autophagosomal_structure_and_are_required_for_autophagy" YMR160W None None biological_process_unknown molecular_function_unknown vacuolar_membrane_(sensu_Fungi) None None 13 575065 577515 YMR160W S000004770 "ORF,_Uncharacterized" Putative_protein_of_unknown_function;_green_fluorescent_protein_(GFP)-fusion_protein_localizes_to_the_membrane_of_the_vacuole;_mutant_has_enhanced_sensitivity_to_overexpression_of_mutant_huntingtin;_YMR160W_is_not_an_essential_gene YMR161W HLJ1 None protein_folding* chaperone_regulator_activity* endoplasmic_reticulum* None None 13 577717 578391 YMR161W S000004771 "ORF,_Verified" "Co-chaperone_for_Hsp40p,_anchored_in_the_ER_membrane;_with_its_homolog_Hdj1p_promotes_ER-associated_protein_degradation_(ERAD)_of_integral_membrane_substrates;_similar_to_E._coli_DnaJ" YMR163C INP2 None biological_process_unknown molecular_function_unknown cytoplasm S/G2 None 13 586387 584270 YMR163C S000004773 "ORF,_Verified" Peroxisome-specific_receptor_important_for_peroxisome_inheritance;_co-fractionates_with_peroxisome_membranes_and_co-localizes_with_peroxisomes_in_vivo;_physically_interacts_with_the_myosin_V_motor_Myo2p;_INP2_is_not_an_essential_gene YMR164C MSS11 None pseudohyphal_growth* specific_RNA_polymerase_II_transcription_factor_activity nucleus None None 13 589549 587273 YMR164C S000004774 "ORF,_Verified" Transcription_factor_involved_in_regulation_of_invasive_growth_and_starch_degradation;_controls_the_activation_of_MUC1_and_STA2_in_response_to_nutritional_signals YMR165C PAH1 SMP2 aerobic_respiration* molecular_function_unknown cytoplasm None None 13 592627 590039 YMR165C S000004775 "ORF,_Verified" "Mg2+-dependent_phosphatidate_(PA)_phosphatase,_catalyzes_the_dephosphorylation_of_PA_to_yield_diacylglycerol_and_Pi,_responsible_for_de_novo_lipid_synthesis;_homologous_to_mammalian_lipin_1" YMR166C None None transport transporter_activity mitochondrial_inner_membrane None None 13 594472 593366 YMR166C S000004776 "ORF,_Uncharacterized" Predicted_transporter_of_the_mitochondrial_inner_membrane;_has_similarity_to_human_mitochondrial_ATP-Mg/Pi_carriers;_YMR166C_is_not_an_essential_gene YMR167W MLH1 PMS2 meiotic_recombination DNA_binding* nucleus* None None 13 594885 597194 YMR167W S000004777 "ORF,_Verified" Protein_required_for_mismatch_repair_in_mitosis_and_meiosis_as_well_as_crossing_over_during_meiosis;_forms_a_complex_with_Pms1p_and_Msh2p-Msh3p_during_mismatch_repair;_human_homolog_is_associated_with_hereditary_non-polyposis_colon_cancer YMR169C ALD3 None response_to_stress* aldehyde_dehydrogenase_activity cytoplasm None None 13 600871 599351 YMR169C S000004779 "ORF,_Verified" "Cytoplasmic_aldehyde_dehydrogenase,_involved_in_beta-alanine_synthesis;_uses_NAD+_as_the_preferred_coenzyme;_very_similar_to_Ald2p;_expression_is_induced_by_stress_and_repressed_by_glucose" YMR170C ALD2 None aldehyde_metabolism* aldehyde_dehydrogenase_activity cytoplasm None None 13 603081 601561 YMR170C S000004780 "ORF,_Verified" "Cytoplasmic_aldehyde_dehydrogenase,_involved_in_ethanol_oxidation_and_beta-alanine_biosynthesis;_uses_NAD+_as_the_preferred_coenzyme;_expression_is_stress_induced_and_glucose_repressed;_very_similar_to_Ald3p" YMR171C EAR1 None biological_process_unknown molecular_function_unknown endosome None None 13 605519 603867 YMR171C S000004781 "ORF,_Verified" Specificity_factor_required_for_Rsp5p-dependent_ubiquitination_and_sorting_of_specific_cargo_proteins_at_the_multivesicular_body;_mRNA_is_targeted_to_the_bud_via_the_mRNA_transport_system_involving_She2p YMR172W HOT1 None regulation_of_transcription_from_RNA_polymerase_II_promoter* specific_RNA_polymerase_II_transcription_factor_activity nuclear_chromosome None None 13 605980 608139 YMR172W S000004783 "ORF,_Verified" Transcription_factor_required_for_the_transient_induction_of_glycerol_biosynthetic_genes_GPD1_and_GPP2_in_response_to_high_osmolarity;_targets_Hog1p_to_osmostress_responsive_promoters;_has_similarity_to_Msn1p_and_Gcr1p YMR173W DDR48 FSP DNA_repair ATPase_activity* cytoplasm None Up 13 608688 609980 YMR173W S000004784 "ORF,_Verified" "DNA_damage-responsive_protein,_expression_is_increased_in_response_to_heat-shock_stress_or_treatments_that_produce_DNA_lesions;_contains_multiple_repeats_of_the_amino_acid_sequence_NNNDSYGS" YMR174C PAI3 None vacuolar_protein_catabolism endopeptidase_inhibitor_activity cytoplasm None Up 13 610364 610158 YMR174C S000004786 "ORF,_Verified" "Cytoplasmic_proteinase_A_(Pep4p)_inhibitor,_dependent_on_Pbs2p_and_Hog1p_protein_kinases_for_osmotic_induction;_intrinsically_unstructured,_N-terminal_half_becomes_ordered_in_the_active_site_of_proteinase_A_upon_contact" YMR17